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Publications:  Dr Helen Warren

Ntalla I, Weng LC, Cartwright JH, Hall AW, Sveinbjornsson G, Tucker NR, Choi SH, Chaffin MD et al.(2020). Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction. Nature Communications vol. 11, (1)
10.1038/s41467-020-15706-x
de las Fuentes L, Sung YJ, Noordam R, Winkler T, Feitosa MF, Schwander K, Bentley AR, Brown MR et al.(2020). Gene-educational attainment interactions in a multi-ancestry genome-wide meta-analysis identify novel blood pressure loci. Molecular Psychiatry
10.1038/s41380-020-0719-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/64748
Smit RAJ, Trompet S, Leong A, Goodarzi MO, Postmus I, Warren H, Theusch E, Barnes MR et al.(2019). Statin-induced LDL cholesterol response and type 2 diabetes: a bidirectional two-sample Mendelian randomization study. Pharmacogenomics Journal
10.1038/s41397-019-0125-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62179
Fung K, Ramírez J, Warren HR, Aung N, Lee AM, Tzanis E, Petersen SE, Munroe PB(2019). Genome-wide association study identifies loci for arterial stiffness index in 127,121 UK Biobank participants. Scientific Reports vol. 9, (1)
10.1038/s41598-019-45703-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58757
Marouli E, Del Greco MF, Astley CM, Yang J, Ahmad S, Berndt SI, Caulfield MJ, Evangelou E et al.(2019). Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease. Communications Biology vol. 2, (1)
10.1038/s42003-019-0361-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57678
Irvin MR, Sitlani CM, Floyd JS, Psaty BM, Bis JC, Wiggins KL, Whitsel EA, Sturmer T et al.(2019). Genome-Wide Association Study of Apparent Treatment-Resistant Hypertension in the CHARGE Consortium: The CHARGE Pharmacogenetics Working Group. American Journal of Hypertension vol. 32, (12) 1146-1153.
10.1093/ajh/hpz150
Clark DW, Okada Y, Moore KHS, Mason D, Pirastu N, Gandin I, Mattsson H, Barnes CLK et al.(2019). Associations of autozygosity with a broad range of human phenotypes. Nature Communications vol. 10, (1) 4957-4957.
10.1038/s41467-019-12283-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61102
Teumer A, Trenkwalder T, Kessler T, Jamshidi Y, van den Berg ME, Kaess B, Nelson CP, Bastiaenen R et al.(2019). KCND3 potassium channel gene variant confers susceptibility to electrocardiographic early repolarization pattern. JCI insight
10.1172/jci.insight.131156
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62342
Petersen S, Munroe P, Aung N, Fung K, Vargas J, Yang C, Cabrera CP, Warren H et al.(2019). Genome-wide analysis of left ventricular image-derived phenotypes identifies fourteen loci associated with cardiac morphogenesis and heart failure development. Circulation
10.1161/CIRCULATIONAHA.119.041161
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59778
Iniesta R, Campbell D, Venturini C, Faconti L, Singh S, Irvin MR, Cooper-DeHoff RM, Johnson JA et al.(2019). Gene Variants at Loci Related to Blood Pressure Account for Variation in Response to Antihypertensive Drugs Between Black and White Individuals. Hypertension vol. 74, (3) 614-622.
10.1161/HYPERTENSIONAHA.118.12177
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59345
Singh S, Warren HR, Hiltunen TP, McDonough CW, El Rouby N, Salvi E, Wang Z, Garofalidou T et al.(2019). Genome-Wide Meta-Analysis of Blood Pressure Response to β<inf>1</inf>-Blockers: Results From ICAPS (International Consortium of Antihypertensive Pharmacogenomics Studies). Journal of the American Heart Association vol. 8, (16)
10.1161/JAHA.119.013115
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60742
Sung YJ, De Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR et al.(2019). A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Human Molecular Genetics vol. 28, (15) 2615-2633.
10.1093/hmg/ddz070
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59202
Ramirez J, van Duijvenboden S, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A et al. (2019). Identification of novel loci for heart rate response to exercise and recovery. EUROPEAN JOURNAL OF HUMAN GENETICS. vol. 27, 135-135.
Ntalla I, Weng L, Warren HR, Jamshidi Y, Munroe PB, Lubitz SA, Consortium CHARGEEKG (2019). Multi-ancestry genome-wide association meta-analysis of 293,000 individuals identifies 217 regions for the electrocardiographic PR interval. EUROPEAN JOURNAL OF HUMAN GENETICS. vol. 27, 158-159.
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2019). Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Nature Genetics, (2018), 50, 1, (26-41), 10.1038/s41588-017-0011-x). Nature Genetics vol. 51, (7) 1191-1192.
10.1038/s41588-019-0447-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61615
Noordam R, Young WJ, Salman R, Kanters JK, van den Berg ME, van Heemst D, Lin HJ, Barreto SM et al.(2019). Effects of Calcium, Magnesium, and Potassium Concentrations on Ventricular Repolarization in Unselected Individuals. Journal of the American College of Cardiology vol. 73, (24) 3118-3131.
10.1016/j.jacc.2019.03.519
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62235
Aung N, Vargas JD, Manichaikul AW, Yang C, Cabrera CP, Warren HR, Fung K, Tzanis E et al. (2019). Genetic architecture of left ventricular phenotypes derived from 17,000 CMR studies in the UK Biobank population imaging cohort. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING. vol. 20, 155-156.
van Setten J, Verweij N, Mbarek H, Niemeijer MN, Trompet S, Arking DE, Brody JA, Gandin I et al.(2019). Genome-wide association meta-analysis of 30,000 samples identifies seven novel loci for quantitative ECG traits. European Journal of Human Genetics vol. 27, (6) 952-962.
10.1038/s41431-018-0295-z
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56172
Aung N, Vargas JD, Manichaikul AW, Yang CP, Cabrera CP, Warren HR, Fung K, Tzanis E et al. (2019). Heritability and genotypic correlation of CMR-derived LV phenotypes in the UK Biobank population imaging study. EUROPEAN HEART JOURNAL-CARDIOVASCULAR IMAGING. vol. 20, 377-378.
Marouli E, Del Greco MF, Astley CM, Yang J, Ahmad S, Berndt SI, Caulfield MJ, Evangelou E et al.(2019). Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease. Commun Biol vol. 2, (1)
10.1038/s42003-019-0361-2
Bastiaenen R, Nolte IM, Munroe PB, Riese H, Nelson C, O'Connor H, Gang Y, Warren HR et al.(2019). The narrow-sense and common single nucleotide polymorphism heritability of early repolarization. International Journal of Cardiology vol. 279, 135-140.
10.1016/j.ijcard.2018.09.119
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54484
McDonough CW, Warren HR, Jack JR, Motsinger-Reif AA, El Rouby NM, Gong Y, Mychaleckyj JC, Benavente OR et al. (2019). DRUG-SNP INTERACTIONS AND CARDIOVASCULAR OUTCOMES: A GENOME-WIDE META-ANALYSIS IN THE INTERNATIONAL CONSORTIUM FOR ANTIHYPERTENSIVE PHARMACOGENOMICS STUDIES. CLINICAL PHARMACOLOGY & THERAPEUTICS. vol. 105, S105-S106.
Singh S, Warren HR, Hiltunen TP, Salvi E, El Rouby N, Garofalidou T, Fyhrquist F, Kontula KK et al. (2019). GENOME WIDE META-ANALYSIS OF BLOOD PRESSURE RESPONSE TO B-BLOCKERS: RESULTS FROM INTERNATIONAL CONSORTIUM OF ANTIHYPERTENSIVE PHARMACOGENOMICS STUDIES. CLINICAL PHARMACOLOGY & THERAPEUTICS. vol. 105, S16-S16.
Singh S, Warren HR, Hiltunen TP, Salvi E, El Rouby N, Garofalidou T, Fyhrquist F, Kontula KK et al. (2019). GENOME WIDE META-ANALYSIS OF BLOOD PRESSURE RESPONSE TO B-BLOCKERS: RESULTS FROM INTERNATIONAL CONSORTIUNI OF ANTIHYPERTENSIVE PHARMACOGENOMICS STUDIES. CLINICAL PHARMACOLOGY & THERAPEUTICS. vol. 105, S27-S27.
Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL et al.(2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics vol. 51, (3) 452-469.
10.1038/s41588-018-0334-2
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56167
Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C et al.(2019). Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Molecular Psychiatry
10.1038/s41380-018-0313-0
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55829
Giri A, Hellwege JN, Keaton JM, Park J, Qiu C, Warren HR, Torstenson ES, Kovesdy CP et al.(2019). Trans-ethnic association study of blood pressure determinants in over 750,000 individuals. Nature Genetics vol. 51, (1) 51-62.
10.1038/s41588-018-0303-9
https://qmro.qmul.ac.uk/xmlui/handle/123456789/55066
Brazel DM, Jiang Y, Hughey JM, Turcot V, Zhan X, Gong J, Batini C, Weissenkampen JD et al.(2018). Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Biological Psychiatry
10.1016/j.biopsych.2018.11.024
https://qmro.qmul.ac.uk/xmlui/handle/123456789/57046
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N et al.(2018). Publisher Correction: Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nat Genet vol. 50, (12) 1755-1755.
10.1038/s41588-018-0297-3
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56068
Ramírez J, Duijvenboden SV, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A et al.(2018). Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system. Nature Communications vol. 9, (1)
10.1038/s41467-018-04148-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39943
Evangelou E, Warren HR, Mosen-Ansorena D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N et al.(2018). Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits. Nature Genetics vol. 50, (10) 1412-1425.
10.1038/s41588-018-0205-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/47343
Ng FL, Warren HR, Caulfield MJ(2018). Hypertension genomics and cardiovascular prevention. Ann Transl Med vol. 6, (15) 291-291.
10.21037/atm.2018.06.34
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49368
Prins BP, Mead TJ, Brody JA, Sveinbjornsson G, Ntalla I, Bihlmeyer NA, van den Berg M, Bork-Jensen J et al.(2018). Exome-chip meta-analysis identifies novel loci associated with cardiac conduction, including ADAMTS6. Genome Biology vol. 19, (1)
10.1186/s13059-018-1457-6
https://qmro.qmul.ac.uk/xmlui/handle/123456789/42707
Feitosa MF, Kraja AT, Chasman DI, Sung YJ, Winkler TW, Ntalla I, Guo X, Franceschini N et al.(2018). Novel genetic associations for blood pressure identified via gene-alcohol interaction in up to 570K individuals across multiple ancestries. PLoS One vol. 13, (6) e0198166-e0198166.
10.1371/journal.pone.0198166
https://qmro.qmul.ac.uk/xmlui/handle/123456789/41963
Warren HR, Evangelou E, Mosen D, Mifsud B, Pazoki R, Gao H, Ntritsos G, Dimou N et al. (2018). GENETIC ANALYSIS OF OVER ONE MILLION PEOPLE IDENTIFIES 535 NOVEL LOCI ASSOCIATED WITH BLOOD PRESSURE AND RISK OF CARDIOVASCULAR DISEASE. JOURNAL OF HYPERTENSION. vol. 36, E229-E229.
10.1097/01.hjh.0000539644.13726.3b
Lin H, van Setten J, Smith AV, Bihlmeyer NA, Warren HR, Brody JA, Radmanesh F, Hall L et al.(2018). Common and Rare Coding Genetic Variation Underlying the Electrocardiographic PR Interval. Circulation. Genomic and precision medicine vol. 11, (5)
10.1161/CIRCGEN.117.002037
https://qmro.qmul.ac.uk/xmlui/handle/123456789/39465
Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H et al.(2018). Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes article. Nature Genetics vol. 50, (4) 559-571.
10.1038/s41588-018-0084-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56153
Sung YJ, Winkler TW, de las Fuentes L, Bentley AR, Brown MR, Kraja AT, Schwander K, Ntalla I et al.(2018). A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure. American Journal of Human Genetics vol. 102, (3) 375-400.
10.1016/j.ajhg.2018.01.015
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35963
Pazoki R, Dehghan A, Evangelou E, Warren H, Gao H, Caulfield M, Elliott P, Tzoulaki I(2018). Genetic predisposition to high blood pressure and lifestyle factors: Associations with midlife blood pressure levels and cardiovascular events. Circulation vol. 137, (7) 653-661.
10.1161/CIRCULATIONAHA.117.030898
Bihlmeyer NA, Brody JA, Smith AV, Warren HR, Lin H, Isaacs A, Liu CT, Marten J et al.(2018). ExomeChip-Wide Analysis of 95 626 Individuals Identifies 10 Novel Loci Associated With QT and JT Intervals. Circulation. Genomic and precision medicine vol. 11, (1)
10.1161/CIRCGEN.117.001758
https://qmro.qmul.ac.uk/xmlui/handle/123456789/41884
Munroe PB, Warren HR(2018). Hypertension. Genomic and Precision Medicine: Cardiovascular Disease: Third Edition,
Munroe PB, Addison S, Abrams DJ, Sebire NJ, Cartwright J, Donaldson I, Cohen MM, Mein C et al.(2018). Postmortem Genetic Testing for Cardiac Ion Channelopathies in Stillbirths. Circulation. Genomic and precision medicine vol. 11, (1)
10.1161/CIRCGEN.117.001817
https://qmro.qmul.ac.uk/xmlui/handle/123456789/45703
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2018). Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics vol. 50, (1) 26-35.
10.1038/s41588-017-0011-x
https://qmro.qmul.ac.uk/xmlui/handle/123456789/34563
Ren M, Ng FL, Warren HR, Witkowska K, Baron M, Jia Z, Cabrera C, Zhang R et al.(2018). The biological impact of blood pressure-associated genetic variants in the natriuretic peptide receptor C gene on human vascular smooth muscle. Human Molecular Genetics vol. 27, (1) 199-210.
10.1093/hmg/ddx375
https://qmro.qmul.ac.uk/xmlui/handle/123456789/30823
Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2017). Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nat Genet vol. 50, (5) 765-766.
10.1038/s41588-018-0050-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56169
Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C et al.(2017). Exome-wide association study of plasma lipids in &gt;300,000 individuals. Nature Genetics vol. 49, (12) 1758-1766.
10.1038/ng.3977
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28624
Kraja AT, Cook JP, Warren HR, Surendran P, Liu C, Evangelou E, Manning AK, Grarup N et al.(2017). New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475 000 Individuals. Circulation: Cardiovascular Genetics vol. 10, (5)
10.1161/CIRCGENETICS.117.001778
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56729
Little L, Kraja AT, Cook JP, Warren HR, Newton-Cheh C, Munroe PB, Howson JMM, BP CE et al. (2017). New blood pressure associated loci identified in meta-analyses of 475,000 individuals using the Exome Chip. vol. 31, is. 10, pp. 665-666.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28627
Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P et al.(2017). Corrigendum: Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet vol. 49, (10) 1558-1558.
10.1038/ng1017-1558a
https://qmro.qmul.ac.uk/xmlui/handle/123456789/50805
Sofer T, Wong Q, Hartwig FP, Taylor K, Warren HR, Evangelou E, Cabrera CP, Levy D et al.(2017). Genome-Wide Association Study of Blood Pressure Traits by Hispanic/Latino Background: the Hispanic Community Health Study/Study of Latinos. Sci Rep vol. 7, (1) 10348-10348.
10.1038/s41598-017-09019-1
https://qmro.qmul.ac.uk/xmlui/handle/123456789/28593
Wain LV, Vaez A, Jansen R, Joehanes R, Van Der Most PJ, Erzurumluoglu AM, O'Reilly PF, Cabrera CP et al.(2017). Novel Blood Pressure Locus and Gene Discovery Using Genome-Wide Association Study and Expression Data Sets from Blood and the Kidney. Hypertension vol. 70, (3) e4-e19.
10.1161/HYPERTENSIONAHA.117.09438
https://qmro.qmul.ac.uk/xmlui/handle/123456789/26603
Dale CE, Fatemifar G, Palmer TM, White J, Prieto-Merino D, Zabaneh D, Engmann JEL, Shah T et al.(2017). Causal Associations of Adiposity and Body Fat Distribution with Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis. Circulation vol. 135, (24) 2373-2388.
10.1161/CIRCULATIONAHA.116.026560
https://qmro.qmul.ac.uk/xmlui/handle/123456789/24949
MUNROE PB, Caulfield M, Stirrups K, van den Berg M, Warren H, Cabrera CP(2017). Discovery of novel heart rate-associated loci using the exome chip. Human Molecular Genetics
10.1093/hmg/ddx113
https://qmro.qmul.ac.uk/xmlui/handle/123456789/22369
Munroe PB, Warren HR(2017). Hypertension. Genomic and Precision Medicine: Primary Care: Third Edition,
Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P et al.(2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet vol. 49, (3) 403-415.
10.1038/ng.3768
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19169
Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y et al.(2017). Rare and low-frequency coding variants alter human adult height. Nature vol. 542, (7640) 186-190.
10.1038/nature21039
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23049
Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL, Trompet S, Warren HR et al.(2016). A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. J Med Genet
10.1136/jmedgenet-2016-104112
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19162
Nüesch E, Dale C, Palmer TM, White J, Keating BJ, van Iperen EPA, Goel A, Padmanabhan S et al.(2016). Adult height, coronary heart disease and stroke: A multi-locus Mendelian randomization meta-analysis. International Journal of Epidemiology vol. 45, (6) 1927-1937.
10.1093/ije/dyv074
Rathod KS, Jones DA, Van-Eijl TJA, Tsang H, Warren H, Hamshere SM, Kapil V, Jain AK et al.(2016). Randomised, double-blind, placebo-controlled study investigating the effects of inorganic nitrate on vascular function, platelet reactivity and restenosis in stable angina: Protocol of the NITRATE-OCT study. BMJ Open vol. 6, (12)
10.1136/bmjopen-2016-012728
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18455
Warren HR, van den Berg ME, van der Harst P, Verweij N, Eijgelsheim M, Stricker BH, Munroe PB, Grp CHARGECEKGW (2016). Discovery of Novel Loci Associated with Heart Rate from Exome Chip Analysis. GENETIC EPIDEMIOLOGY. Conference: International Genetic Epidemiology Society vol. 40, 670-670.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18150
Jepson RE, Warren HR, Syme HM, Elliott J, Munroe PB(2016). Uromodulin gene variants and their association with renal function and blood pressure in cats: a pilot study. J Small Anim Pract vol. 57, (11) 580-588.
10.1111/jsap.12582
https://qmro.qmul.ac.uk/xmlui/handle/123456789/23567
Warren HR, Surendran P, Manning AK, van den Berg ME, van der Harst P, Verweij N, Eijgelsheim M, Stricker BHC et al.(2016). Novel loci discovery for blood pressure and heart rate using the Exome chip. JOURNAL OF HUMAN HYPERTENSION vol. 30, (10) 653-653.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18151
Smit RA, Postmus I, Trompet S, Barnes MR, Warren H, Arsenault BJ, Chasman DI, Cupples LA et al.(2016). Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment. Pharmacogenomics vol. 17, (15) 1621-1628.
10.2217/pgs-2016-0091
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16224
MUNROE PB(2016). Trans-ancestry meta-analyses identify novel rare and common variants associated with blood pressure and hypertension. Nature Genetics
10.1038/ng.3654
https://qmro.qmul.ac.uk/xmlui/handle/123456789/13707
MUNROE PB(2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics
10.1038/ng.3667
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15563
Postmus I, Warren HR, Trompet S, Arsenault BJ, Avery CL, Bis JC, Chasman DI, de Keyser CE et al.(2016). Meta-analysis of genome-wide association studies of HDL cholesterol response to statins. Journal of Medical Genetics
10.1136/jmedgenet-2016-103966
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15127
Kanoni S, Masca NGD, Stirrups KE, Varga TV, Warren HR, Scott RA, Southam L, Zhang W et al.(2016). Analysis with the exome array identifies multiple new independent variants in lipid loci. Human Molecular Genetics vol. 25, (18) ddw227-ddw227.
10.1093/hmg/ddw227
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14812
HOWARD SR, Guasti L, Ruiz-Babot G, Mancini A, David A, Storr H, Metherell LA, Sternberg MJE et al.(2016). IGSF10 mutations dysregulate gonadotropin‐releasing hormone neuronal migration resulting in delayed puberty. EMBO Molecular Medicine vol. 8, (6) 626-42.
10.15252/emmm.201606250
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18622
Leusink M, Maitland-Van Der Zee AH, Ding B, Drenos F, Van Iperen EPA, Warren HR, Caulfield MJ, Cupples LA et al.(2016). A genetic risk score is associated with statin-induced low-density lipoprotein cholesterol lowering. Pharmacogenomics vol. 17, (6) 583-591.
10.2217/pgs.16.8
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12771
White J, Sofat R, Hemani G, Shah T, Engmann J, Dale C, Shah S, Kruger FA et al.(2016). Plasma urate concentration and risk of coronary heart disease: A Mendelian randomisation analysis. The Lancet Diabetes and Endocrinology vol. 4, (4) 327-336.
10.1016/S2213-8587(15)00386-1
Warren HR, Surendran P, Drenos F, Young R, Cook JP, Manning AK, Grarup N, Sim X et al. (2015). Investigating the Association of Rare Genetic Variants with Blood Pressure traits. GENETIC EPIDEMIOLOGY. vol. 39, 591-591.
Joshi PK, Esko T, Mattsson H, Eklund N, Gandin I, Nutile T, Jackson AU, Schurmann C et al.(2015). Directional dominance on stature and cognition in diverse human populations. Nature vol. 523, (7561) 459-462.
10.1038/nature14618
https://qmro.qmul.ac.uk/xmlui/handle/123456789/12751
Orr N, Dudbridge F, Dryden N, Maguire S, Novo D, Perrakis E, Johnson N, Ghoussaini M et al.(2015). Fine-mapping identifies two additional breast cancer susceptibility loci at 9q31.2. Human Molecular Genetics vol. 24, (10) 2966-2984.
10.1093/hmg/ddv035
Locke AE, Kahali B, Berndt SI, Justice AE, Pers TH, Day FR, Powell C, Vedantam S et al.(2015). Genetic studies of body mass index yield new insights for obesity biology. Nature vol. 518, (7538) 197-206.
10.1038/nature14177
https://qmro.qmul.ac.uk/xmlui/handle/123456789/6989
Cabrera CP, Ng FL, Warren HR, Barnes MR, Munroe PB, Caulfield MJ(2015). Exploring hypertension genome-wide association studies findings and impact on pathophysiology, pathways, and pharmacogenetics. Wiley Interdisciplinary Reviews: Systems Biology and Medicine vol. 7, (2) 73-90.
10.1002/wsbm.1290
Postmus I, Trompet S, Warren HR, Jukema JW, Caulfield MJ, Consortium GIST (2014). Pharmacogenetic GWAS meta-analysis of LDL cholesterol response to statins. JOURNAL OF HUMAN HYPERTENSION. vol. 28, 624-624.
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