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Publications:  Dr Andrejs Brauns

Klymenko T, Bloehdorn J, Bahlo J, Robrecht S, Akylzhanova G, Cox K, Estenfelder S, Wang J et al.(2017). Lamin B1 regulates somatic mutations and progression of B-cell malignancies. Leukemia vol. 32, (2) 364-375.
10.1038/leu.2017.255
Klymenko T, Bloehdorn J, Bahlo J, Robrecht S, Wang J, Fischer K, Akylzhanova G, Edelmann J et al. (2017). NUCLEAR LAMINA REGULATES SOMATIC HYPERMUTATION AND PROGRESSION OF B CELL MALIGNANCIES. HAEMATOLOGICA. vol. 102, 228-228.
Dou Z, Ivanov A, Adams PD, Berger SL(2016). Mammalian autophagy degrades nuclear constituents in response to tumorigenic stress. Autophagy vol. 12, (8) 1416-1417.
10.1080/15548627.2015.1127465
Vilventhraraja E, Gribben J, Ivanov A (2016). EXPLOITING OXIDATIVE PHOSPHORYLATION TO IMPROVE ANTIBODY THERAPY OF LYMPHOMA. HAEMATOLOGICA. vol. 101, 574-575.
Dou Z, Xu C, Donahue G, Shimi T, Pan J-A, Zhu J, Ivanov A, Capell BC et al.(2015). Autophagy mediates degradation of nuclear lamina. Nature vol. 527, (7576) 105-109.
10.1038/nature15548
Rai TS, Cole JJ, Nelson DM, Dikovskaya D, Faller WJ, Vizioli MG, Hewitt RN, Anannya O et al.(2014). HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia. Genes Dev vol. 28, (24) 2712-2725.
10.1101/gad.247528.114
Ivanov A, Pawlikowski J, Manoharan I, van Tuyn J, Nelson DM, Rai TS, Shah PP, Hewitt G et al.(2013). Lysosome-mediated processing of chromatin in senescence. J Cell Biol vol. 202, (1) 129-143.
10.1083/jcb.201212110
Jackson TR, Salmina K, Huna A, Inashkina I, Jankevics E, Riekstina U, Kalnina Z, Ivanov A et al.(2013). DNA damage causes TP53-dependent coupling of self-renewal and senescence pathways in embryonal carcinoma cells. CELL CYCLE vol. 12, (3) 430-441.
10.4161/cc.23285
Honeychurch J, Alduaij W, Azizyan M, Cheadle EJ, Pelicano H, Ivanov A, Huang P, Cragg MS et al.(2012). Antibody-induced nonapoptotic cell death in human lymphoma and leukemia cells is mediated through a novel reactive oxygen species-dependent pathway. Blood vol. 119, (15) 3523-3533.
10.1182/blood-2011-12-395541
Alduaij W, Ivanov A, Honeychurch J, Cheadle EJ, Potluri S, Lim SH, Shimada K, Chan CHT et al.(2011). Novel type II anti-CD20 monoclonal antibody (GA101) evokes homotypic adhesion and actin-dependent, lysosome-mediated cell death in B-cell malignancies. Blood vol. 117, (17) 4519-4529.
10.1182/blood-2010-07-296913
Ivanov A, Adams PD(2011). A damage limitation exercise. Nature Cell Biology vol. 13, (3) 193-195.
10.1038/ncb0311-193
Salmina K, Jankevics E, Huna A, Perminov D, Radovica I, Klymenko T, Ivanov A, Jascenko E et al.(2010). Up-regulation of the embryonic self-renewal network through reversible polyploidy in irradiated p53-mutant tumour cells. Experimental Cell Research vol. 316, (13) 2099-2112.
10.1016/j.yexcr.2010.04.030
Alduau W, Potluri S, Ivanov A, Honeychurch J, Beers SA, Chan C, Shimada K, Glennie MJ et al. (2009). New-Generation Anti-CD20 Monoclonal Antibody (GA101) Evokes Homotypic Adhesion and Actin-Dependent, Lysosome-Mediated Cell Death in B-Cell Lymphoma. BLOOD. vol. 114, 302-303.
Ivanov A, Beers SA, Walshe CA, Honeychurch J, Alduaij W, Cox KL, Potter KN, Murray S et al.(2009). Monoclonal antibodies directed to CD20 and HLA-DR can elicit homotypic adhesion followed by lysosome-mediated cell death in human lymphoma and leukemia cells. J Clin Invest vol. 119, (8) 2143-2159.
10.1172/JCI37884
Illidge T, Ivanov A, Beers SA, Walshe C, Chan C, Alduaij W, Glennie MJ, Cragg MS(2008). Novel Mechanisms of Non-Apoptotic Cell Death Evoked by Type II Anti-CD20 (Tositumomab) and HLA-DR Monoclonal Antibodies. BLOOD vol. 112, (11) 326-326.
Erenpreisa J, Ivanov A, Wheatley SP, Kosmacek EA, Ianzini F, Anisimov AP, Mackey M, Davis PJ et al.(2008). Endopolyploidy in irradiated p53-deficient tumour cell lines: Persistence of cell division activity in giant cells expressing Aurora-B kinase. CELL BIOLOGY INTERNATIONAL vol. 32, (9) 1044-1056.
10.1016/j.cellbi.2008.06.003
Ivanov A, Swann R, Illidge T(2008). New insights into the mechanisms of action of radioimmunotherapy in lymphoma. J Pharm Pharmacol vol. 60, (8) 987-998.
10.1211/jpp.60.8.0006
Ivanov A, Krysov S, Cragg MS, Illidge T(2008). Radiation therapy with tositumomab (B1) anti-CD20 monoclonal antibody initiates extracellular signal-regulated kinase/mitogen-activated protein kinase-dependent cell death that overcomes resistance to apoptosis. Clin Cancer Res vol. 14, (15) 4925-4934.
10.1158/1078-0432.CCR-07-5072
Ivanov A, Cragg MS, Illidge TM (2006). Treatment with the anti-CD20 antibody (B1) and irradiation result in synergistic cytotoxicity that is dependent on MAPK activation. BLOOD. vol. 108, 710A-710A.
Kalejs M, Ivanov A, Plakhins G, Cragg MS, Emzinsh D, Lllidge TM, Erenpreisa J(2006). Upregulation of meiosis-specific genes in lymphoma cell lines following genotoxic insult and induction of mitotic catastrophe. BMC Cancer vol. 6,
10.1186/1471-2407-6-6
Erenpreisa J, Kalejs M, Ianzini F, Kosmacek EA, Mackey MA, Emzinsh D, Cragg MS, Ivanov A et al.(2005). Segregation of genomes in polyploid tumour cells following mitotic catastrophe. CELL BIOLOGY INTERNATIONAL vol. 29, (12) 1005-1011.
10.1016/j.cellbi.2005.10.008
Cragg MS, Walshe CA, Ivanov AO, Glennie MJ(2005). The biology of CD20 and its potential as a target for mAb therapy. Curr Dir Autoimmun vol. 8, 140-174.
10.1159/000082102
Ivanov A, Cragg MS, Erenpreisa J, Emzinsh D, Lukman H, Illidge TM(2003). Endopolyploid cells produced after severe genotoxic damage have the potential to repair DNA double strand breaks. J Cell Sci vol. 116, (Pt 20) 4095-4106.
10.1242/jcs.00740
Ivanov A, Cragg MS, Erenpreisa J, Emzinsh D, Lukman H, Illidge TM(2003). Endopolyploid cells produced aftere severe genotoxic damage have the potential to repair DNA double strand breaks. Journal of Cell Science vol. 116, (20) 4095-4106.
10.1242/jcs.00740
Ivanov A, Cragg M, Erenpreisa J, Illidge T (2003). Radiation-induced MAPK activation produces polyploid tumour cells that undergo DNA double strand break repair. BRITISH JOURNAL OF CANCER. vol. 88, S26-S26.
Erenpreisa J, Erenpreiss J, Freivalds T, Slaidina M, Krampe R, Butikova J, Ivanov A, Pjanova D(2003). Toluidine blue test for sperm DNA integrity and elaboration of image cytometry algorithm. Cytometry A vol. 52, (1) 19-27.
10.1002/cyto.a.10015
Erenpreisa J, Ivanov A, Cragg M, Selivanova G, Illidge T(2002). Nuclear envelope-limited chromatin sheets are part of mitotic death. Histochem Cell Biol vol. 117, (3) 243-255.
10.1007/s00418-002-0382-6
Ivanov A, Cragg MS, Illidge TM, Erenpreisa J(2000). The delayed action of the spindle checkpoint in p53 mutated lymphoid tumour cells. BRITISH JOURNAL OF CANCER vol. 83, 58-58.
Erenpreisa JE, Ivanov A, Dekena G, Vitina A, Krampe R, Freivalds T, Selivanova G, Roach HI(2000). Arrest in metaphase and anatomy of mitotic catastrophe: mild heat shock in two human osteosarcoma cell lines. Cell Biol Int vol. 24, (2) 61-70.
10.1006/cbir.1999.0466
BRAUNS A. ONCOGENE-EXPRESSING SENESCENT MELANOCYTES UPREGULATE MHC CLASS II, A CANDIDATE MELANOMA SUPPRESSOR FUNCTION. The Journal of Investigative Dermatology
10.1016/j.jid.2017.05.030
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