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  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Anne O'Loghlen Velicia

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Carpintero-Fernández P, Borghesan M, Eleftheriadou O, Pan-Castillo B, Fafián-Labora JA, Mitchell TP, Yuste A, Ogrunc M et al. ( 2022 ) . Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence . Cell Death and Disease vol. 13 , ( 2 )
O’Loghlen A ( 2022 ) . The potential of aging rejuvenation . Cell Cycle vol. 21 , ( 2 ) 111 - 116 .
Prasanna PG, Citrin DE, Hildesheim J, Ahmed MM, Venkatachalam S, Riscuta G, Xi D, Zheng G et al. ( 2021 ) . Therapy-Induced Senescence: Opportunities to Improve Anticancer Therapy . Journal of the National Cancer Institute vol. 113 , ( 10 ) 1285 - 1298 .
Fafián-Labora JA, O’Loghlen A ( 2021 ) . NF-κB/IKK activation by small extracellular vesicles within the SASP . Aging Cell vol. 20 , ( 7 )
Alarcon-Gil J, Posada-Gracia M, Pascual-Guerra J, Fafian-Labora JA, Paino CL, Escobar-Peso A, Casarejos MJ, O'Loghlen A et al. ( 2021 ) . Small extracellular vesicles from primary astrocytes exert a neuroprotective effect on damaged primary neuronal cultures . GLIA . vol. 69 , E304 - E305 .
O'Loghlen A ( 2021 ) . Small extracellular vesicles regulate senescence and ageing . EUROPEAN JOURNAL OF CLINICAL INVESTIGATION . vol. 51 , 122 - 122 .
Guerrini L, Garcia-Rico E, O’loghlen A, Giannini V, Alvarez-Puebla RA ( 2021 ) . Surface-enhanced raman scattering (Sers) spectroscopy for sensing and characterization of exosomes in cancer diagnosis . Cancers vol. 13 , ( 9 )
Rodriguez-Navarro JA, Pascual-Guerra J, Sacristan S, Nogales MDC, Fafián-Labora JA, O’Loghlen A ( 2020 ) . Extracellular vesicles as potential tools for regenerative therapy . Molecular and Cellular Oncology vol. 7 , ( 6 )
Fafián-Labora JA, O'Loghlen A ( 2020 ) . Classical and Nonclassical Intercellular Communication in Senescence and Ageing . Trends in Cell Biology vol. 30 , ( 8 ) 628 - 639 .
Fafián-Labora JA, Rodríguez-Navarro JA, O'Loghlen A ( 2020 ) . Small Extracellular Vesicles Have GST Activity and Ameliorate Senescence-Related Tissue Damage . Cell Metabolism vol. 32 , ( 1 ) 71 - 86.e5 .
Borghesan M, Fafián-Labora J, Eleftheriadou O, Carpintero-Fernández P, Paez-Ribes M, Vizcay-Barrena G, Swisa A, Kolodkin-Gal D et al. ( 2019 ) . Small Extracellular Vesicles Are Key Regulators of Non-cell Autonomous Intercellular Communication in Senescence via the Interferon Protein IFITM3 . Cell Reports vol. 27 , ( 13 ) 3956 - 3971.e6 .
Fafián-Labora J, Carpintero-Fernández P, Jordan SJD, Shikh-Bahaei T, Abdullah SM, Mahenthiran M, Rodríguez-Navarro JA, Niklison-Chirou MV et al. ( 2019 ) . FASN activity is important for the initial stages of the induction of senescence . Cell Death and Disease vol. 10 , ( 4 )
O'Loghlen A ( 2018 ) . Role for extracellular vesicles in the tumour microenvironment . Philos Trans R Soc Lond B Biol Sci vol. 373 , ( 1737 )
Théry C, Witwer KW, Aikawa E, Alcaraz MJ, Anderson JD, Andriantsitohaina R, Antoniou A, Arab T et al. ( 2018 ) . Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines . Journal of Extracellular Vesicles vol. 7 , ( 1 )
Carpintero-Fernández P, Fafián-Labora J, O'Loghlen A ( 2017 ) . Technical Advances to Study Extracellular Vesicles . Front Mol Biosci vol. 4 , 79 - 79 .
Borghesan M, O'Loghlen A ( 2017 ) . Integrins in senescence and aging . Cell Cycle vol. 16 , ( 10 ) 909 - 910 .
( 2017 ) . Erratum . Aging Cell vol. 16 , ( 2 )
Rapisarda V, Borghesan M, Miguela V, Encheva V, Snijders AP, Lujambio A, O'Loghlen A ( 2017 ) . Integrin Beta 3 Regulates Cellular Senescence by Activating the TGF-β Pathway . Cell Reports vol. 18 , ( 10 ) 2480 - 2493 .
O'Loghlen A, Brookes S, Martin N, Rapisarda V, Peters G, Gil J ( 2015 ) . CBX7 and miR-9 are part of an autoregulatory loop controlling p16<sup>INK</sup><sup>4a</sup> . Aging Cell vol. 14 , ( 6 ) 1113 - 1121 .
O'Loghlen A, Martin N, Krusche B, Pemberton H, Alonso MM, Chandler H, Brookes S, Parrinello S et al. ( 2015 ) . The nuclear receptor NR2E1/TLX controls senescence . Oncogene vol. 34 , ( 31 ) 4069 - 4077 .
Gil J, O'Loghlen A ( 2014 ) . PRC1 complex diversity: where is it taking us? . Trends Cell Biol vol. 24 , ( 11 ) 632 - 641 .
Gil J, O'Loghlen A ( 2014 ) . PRC1 complex diversity: Where is it taking us? . Trends in Cell Biology vol. 24 , ( 11 ) 632 - 641 .
Martin N, Popov N, Aguilo F, O'Loghlen A, Raguz S, Snijders AP, Dharmalingam G, Li S et al. ( 2013 ) . Interplay between Homeobox proteins and Polycomb repressive complexes in p16INK⁴a regulation . EMBO J vol. 32 , ( 7 ) 982 - 995 .
O'Loghlen A, Muñoz-Cabello AM, Gaspar-Maia A, Wu H-A, Banito A, Kunowska N, Racek T, Pemberton HN et al. ( 2012 ) . MicroRNA regulation of Cbx7 mediates a switch of Polycomb orthologs during ESC differentiation . Cell Stem Cell vol. 10 , ( 1 ) 33 - 46 .
O''LOGHLEN VELICIA AP, Gil J ( 2011 ) . CBX7 (chromobox homolog 7) . Atlas of Genetics and Cytogenetics in Oncology and Haematology
Lazzerini G, Del Turco S, Basta G, O'Loghlen A, Zampolli A, Caterina RD ( 2009 ) . Prominent role of NF-kappaB in the induction of endothelial activation by endogenous nitric oxide inhibition . Nitric Oxide vol. 21 , ( 3-4 ) 184 - 191 .
Acosta JC, O'Loghlen A, Banito A, Raguz S, Gil J ( 2008 ) . Control of senescence by CXCR2 and its ligands . Cell Cycle vol. 7 , ( 19 ) 2956 - 2959 .
Acosta JC, O'Loghlen A, Banito A, Guijarro MV, Augert A, Raguz S, Fumagalli M, Da Costa M et al. ( 2008 ) . Chemokine signaling via the CXCR2 receptor reinforces senescence . Cell vol. 133 , ( 6 ) 1006 - 1018 .
Dinarina A, Ruiz EJ, O'Loghlen A, Mouron S, Perez L, Nebreda AR ( 2008 ) . Negative regulation of cell-cycle progression by RINGO/Speedy E . Biochem J vol. 410 , ( 3 ) 535 - 542 .
O'Loghlen A, González VM, Jurado T, Salinas M, Martín ME ( 2007 ) . Characterization of the activity of human MAP kinase-interacting kinase Mnk1b . Biochim Biophys Acta vol. 1773 , ( 9 ) 1416 - 1427 .
O'Loghlen A, Pérez-Morgado MI, Salinas M, Martín ME ( 2006 ) . N-acetyl-cysteine abolishes hydrogen peroxide-induced modification of eukaryotic initiation factor 4F activity via distinct signalling pathways . Cell Signal vol. 18 , ( 1 ) 21 - 31 .
O'Loghlen A, Perez-Morgado MI, Salinas M, Martin ME ( 2005 ) . Reversion of the hydrogen peroxide-induced modification of eukaryotic initiation factor 4F activity by N-acetyl-cysteine involves distinct signaling pathways . FEBS JOURNAL . vol. 272 , 427 - 428 .
O'Loghlen A, González VM, Salinas M, Martín ME ( 2004 ) . Suppression of human Mnk1 by small interfering RNA increases the eukaryotic initiation factor 4F activity in HEK293T cells . FEBS Lett vol. 578 , ( 1-2 ) 31 - 35 .
O'Loghlen A, González VM, Piñeiro D, Pérez-Morgado MI, Salinas M, Martín ME ( 2004 ) . Identification and molecular characterization of Mnk1b, a splice variant of human MAP kinase-interacting kinase Mnk1 . Exp Cell Res vol. 299 , ( 2 ) 343 - 355 .
García L, O'Loghlen A, Martín ME, Burda J, Salinas M ( 2004 ) . Does phosphorylation of eukaryotic elongation factor eEF2 regulate protein synthesis in ischemic preconditioning? . J Neurosci Res vol. 77 , ( 2 ) 292 - 298 .
Martin ME, O'Loghlen A, Perez-Morgado MI, Salinas M ( 2003 ) . Reversible inhibition of the protein phosphatase 1 by oxidation. Potential regulation of EIF2 phosphorylation . JOURNAL OF NEUROCHEMISTRY . vol. 87 , 160 - 160 .
O'Loghlen A, Pérez-Morgado MI, Salinas M, Martín ME ( 2003 ) . Reversible inhibition of the protein phosphatase 1 by hydrogen peroxide. Potential regulation of eIF2 alpha phosphorylation in differentiated PC12 cells . Arch Biochem Biophys vol. 417 , ( 2 ) 194 - 202 .
Basta G, Lazzerini G, Del Turco S, O'Loghlen A, Schmidt AM, Ratto GM, De Caterina R ( 2001 ) . NAD(P)H oxidase-mediated generation of reactive oxygen species is implicated in the endothelial induction of VCAM-1 and ICAM-1, but not E-selectin, by advanced glycation endproducts . CIRCULATION vol. 104 , ( 17 ) 231 - 231 .
Basta G, Lazzerini G, Del Turco S, O'Loghlen A, Schmidt AM, Ratto GM, De Caterina R ( 2001 ) . Effects of NAD(P)H oxidase inhibitors on AGEs-induced adhesion proteins expression in endothelial cells . EUROPEAN HEART JOURNAL vol. 22 , 369 - 369 .
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