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Publications:  Mrs Clare Thompson

Torres-Pérez JV, Naeem H, Thompson CL, Knight MM, Novak P(2020). Nanoscale mapping reveals functional differences in ion channels populating the membrane of primary cilia. Cellular Physiology and Biochemistry vol. 54, (1) 15-26.
10.33594/000000202
Fu S, Thompson CL, Ali A, Wang W, Chapple JP, Mitchison HM, Beales PL, Wann AKT et al.(2019). Mechanical loading inhibits cartilage inflammatory signalling via an HDAC6 and IFT-dependent mechanism regulating primary cilia elongation. Osteoarthritis and Cartilage vol. 27, (7) 1064-1074.
10.1016/j.joca.2019.03.003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56961
Harris C, THORPE SD, Rushwan S, Wang W, THOMPSON C, Peacock J, KNIGHT M, Gooptu B et al.(2019). An in vitro investigation of the inflammatory response to the strain amplitudes which occur during high frequency oscillation ventilation and conventional mechanical ventilation. Journal of Biomechanics
10.1016/j.jbiomech.2019.03.024
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56712
O¿Toole SM, Watson DS, Novoselova TV, Romano LEL, King PJ, Bradshaw TY, Thompson CL, Knight MM et al.(2019). Oncometabolite induced primary cilia loss in pheochromocytoma. Endocrine-Related Cancer vol. 26, (1) 165-180.
10.1530/ERC-18-0134
https://qmro.qmul.ac.uk/xmlui/handle/123456789/44923
Gambassi S, Geminiani M, Thorpe SD, Bernardini G, Millucci L, Braconi D, Orlandini M, Thompson CL et al.(2017). Smoothened-antagonists reverse homogentisic acid-induced alterations of Hedgehog signaling and primary cilium length in alkaptonuria. Journal of Cellular Physiology vol. 232, (11) 3103-3111.
10.1002/jcp.25761
https://qmro.qmul.ac.uk/xmlui/handle/123456789/18493
Thompson CL, Plant JC, Wann AK, Bishop CL, Novak P, Mitchison HM, Beales PL, Chapple JP et al.(2017). Chondrocyte expansion is associated with loss of primary cilia and disrupted hedgehog signalling. Eur Cell Mater vol. 34, 128-141.
10.22203/eCM.v034a09
https://qmro.qmul.ac.uk/xmlui/handle/123456789/26203
Schwarz N, Lane A, Jovanovic K, Parfitt DA, Aguila M, Thompson CL, da Cruz L, Coffey PJ et al.(2017). Arl3 and RP2 regulate the trafficking of ciliary tip kinesins. Hum Mol Genet vol. 26, (13) 2480-2492.
10.1093/hmg/ddx143
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56965
Schwarz N, Lane A, Jovanovic K, Parfitt DA, Aguila M, Thompson CL, da Cruz L, Coffey PJ et al.(2017). Arl3 and RP2 regulate the trafficking of ciliary tip kinesins. (CORRIGENDUM). Hum Mol Genet vol. 26, (17) 3451-3451.
10.1093/hmg/ddx245
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56962
THORPE SD, Gambassi S, Thompson CL, Chandrakumar C, Santucci A, Knight MM(2017). Reduced Primary Cilia Length and Altered Arl13b Expression Are Associated with Deregulated Chondrocyte Hedgehog Signalling in Alkaptonuria. Journal of Cellular Physiology
10.1002/jcp.25839
https://qmro.qmul.ac.uk/xmlui/handle/123456789/19413
Thompson CL, Chapple JP, Beales PL, Mitchison HM, Ramachandran M, Knight MM (2017). Polycystins are required for primary cilia-mediated mechanotransduction in chondrocytes. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 98, A14-A14.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/56620
Kelly T-AN, Thompson CL, Tan E, Wann AK, Thorpe SD, Chapple JP, Hung CT, Knight MM (2016). Chondrocyte dedifferentiation down regulates mechano-responsiveness and hedgehog signalling associated with changes in primary cilia structure. Osteoarthritis and Cartilage. Conference: World Congress of the Osteoarthritis-Research-Society-International (OARSI) on Osteoarthritis from: 31/03/2016 to: 03/04/2016, vol. 24, S342-S343.
10.1016/j.joca.2016.01.614
KNIGHT MM, wang W, wang Z, wann A, thompson C, hassen A(2016). IFT88 influences chondrocyte actin organization and biomechanics. Osteoarthritis and Cartilage
10.1016/j.joca.2015.10.003
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9613
KNIGHT MM, Thompson CL, Wiles A, Poole CA(2016). Lithium chloride modulates chondrocyte primary cilia and inhibits hedgehog signalling. The FASEB Journal
10.1096/fj.15-274944
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9616
Sliogeryte K, Thorpe SD, Wang Z, Thompson CL, Gavara N, Knight MM(2016). Differential effects of LifeAct-GFP and actin-GFP on cell mechanics assessed using micropipette aspiration. Journal of Biomechanics vol. 49, (2) 310-317.
10.1016/j.jbiomech.2015.12.034
https://qmro.qmul.ac.uk/xmlui/handle/123456789/35743
Thompson CL, Patel R, Kelly T-AN, Wann AKT, Hung CT, Chapple JP, Knight MM(2015). Hedgehog signalling does not stimulate cartilage catabolism and is inhibited by Interleukin-1β. Arthritis Research & Therapy vol. 17, (1)
10.1186/s13075-015-0891-z
https://qmro.qmul.ac.uk/xmlui/handle/123456789/15847
Thompson CL, Poole CA, Knight MM(2015). Lithium chloride modulates chondrocyte primary cilia and inhibits Hedgehog signaling. The FASEB Journal vol. 100, (4) A39-A40.
10.1096/fj.15-274944
https://qmro.qmul.ac.uk/xmlui/handle/123456789/62499
KNIGHT MM, Thompson CL, Yasmin H, Varone A, Wiles A, Poole CA(2015). Lithium chloride prevents interleukin- 1β induced cartilage degradation and loss of mechanical properties. Journal of Orthopaedic Research
10.1002/jor.22913
https://qmro.qmul.ac.uk/xmlui/handle/123456789/16043
Thompson CL, Poole CA, Knight MM (2015). Lithium chloride triggers primary cilia elongation and inhibits hedgehog signalling in articular chondrocytes. vol. 96, is. 2, pp. A6-A6.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9619
Thompson CL, Chapple JP, Knight MM (2014). Primary cilia disassembly down regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 95, A32-A32.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9657
Thompson CL, Chapple JP, Knight MM(2014). Primary cilia disassembly down-regulates mechanosensitive hedgehog signalling: a feedback mechanism controlling ADAMTS-5 expression in chondrocytes. Osteoarthritis Cartilage vol. 22, (3) 490-498.
10.1016/j.joca.2013.12.016
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9635
McMurray RJ, Wann AKT, Thompson CL, Connelly JT, Knight MM(2013). Surface topography regulates wnt signaling through control of primary cilia structure in mesenchymal stem cells. Sci Rep vol. 3,
10.1038/srep03545
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54206
Wann AK, Thompson CL, Chapple JP, Knight MM(2013). Interleukin-1β sequesters hypoxia inducible factor 2α to the primary cilium. Cilia vol. 2, (1)
10.1186/2046-2530-2-17
https://qmro.qmul.ac.uk/xmlui/handle/123456789/9615
Prodromou NV, Thompson CL, Osborn DPS, Cogger KF, Ashworth R, Knight MM, Beales PL, Chapple JP(2012). Heat shock induces rapid resorption of primary cilia. J Cell Sci vol. 125, (Pt 18) 4297-4305.
10.1242/jcs.100545
Thompson CL, Chapple JP, Knight MM (2012). Mechanical strain reduces primary cilia length and stimulates hedgehog signalling in adult chondrocytes. INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY. vol. 93, A20-A20.
Thompson CL, Chapple JP, Knight MM (2012). MECHANICAL STRAIN STIMULATES HEDGEHOG SIGNALLING IN ADULT ARTICULAR CHONDROCYTES AND REDUCES PRIMARY CILIA LENGTH. OSTEOARTHRITIS AND CARTILAGE. vol. 20, S242-S242.
10.1016/j.joca.2012.02.400
Wann AKT, Thompson C, Knight MM(2012). The role of the primary cilium in chondrocyte response to mechanical loading. Mechanically Gated Channels and their Regulation,
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