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Research

Publications: Dr Natalie McCloskey

Bodkin J, Beyrau M, Woodfin A, Colom B, McCloskey N, Bianchi M, Nourshargh S ( 2013 ) . Dynamics of neutrophil-endothelial interactions governs dissemination of local inflammation . EUROPEAN JOURNAL OF CLINICAL INVESTIGATION vol. 43 , 30 - 30 .
Veninga H, de Groot DM, McCloskey N, Owens BM, Dessing MC, Verbeek JS, Nourshargh S, van Eenennaam H et al. ( 2011 ) . CD97 antibody depletes granulocytes in mice under conditions of acute inflammation via a Fc receptor-dependent mechanism . J Leukoc Biol vol. 89 , ( 3 ) 413 - 421 .
Chowdhury M, Forouhi O, Dayal S, McCloskey N, Gould HJ, Felsenfeld G, Fear DJ ( 2008 ) . Analysis of intergenic transcription and histone modification across the human immunoglobulin heavy-chain locus . Proc Natl Acad Sci U S A vol. 105 , ( 41 ) 15872 - 15877 .
Karagiannis SN, Bracher MG, Beavil RL, Beavil AJ, Hunt J, McCloskey N, Thompson RG, East N et al. ( 2008 ) . Role of IgE receptors in IgE antibody-dependent cytotoxicity and phagocytosis of ovarian tumor cells by human monocytic cells . CANCER IMMUNOL IMMUN vol. 57 , ( 2 ) 247 - 263 .
Karagiannis SN, Bracher MG, Hunt J, McCloskey N, Beavil RL, Beavil AJ, Fear DJ, Thompson RG et al. ( 2007 ) . IgE-antibody-dependent immunotherapy of solid tumors: Cytotoxic and phagocytic mechanisms of eradication of ovarian cancer cells . J IMMUNOL vol. 179 , ( 5 ) 2832 - 2843 .
McCloskey N, Hunt J, Beavil RL, Jutton MR, Grundy GJ, Girardi E, Fabiane SM, Fear DJ et al. ( 2007 ) . Soluble CD23 monomers inhibit and oligomers stimulate IGE synthesis in human B cells . J Biol Chem vol. 282 , ( 33 ) 24083 - 24091 .
Fear DJ, McCloskey N, Lee TH, Felsenfeld G, Gould H ( 2005 ) . Immunoglobulin class switch recombination to IgE is not regulated by DNA methylation . IMMUNOLOGY . vol. 116 , 31 - 31 .
Fear DJ, McCloskey N, O'Connor B, Felsenfeld G, Gould HJ ( 2004 ) . Transcription of Ig germline genes in single human B cells and the role of cytokines in isotype determination . J Immunol vol. 173 , ( 7 ) 4529 - 4538 .
Gould HJ, Sutton BJ, Beavil AJ, Beavil RL, McCloskey N, Coker HA, Fear D, Smurthwaite L ( 2003 ) . The biology of IGE and the basis of allergic disease . Annu Rev Immunol vol. 21 , 579 - 628 .
Zapata JM, Krajewska M, Krajewski S, Kitada S, Welsh K, Monks A, McCloskey N, Gordon J et al. ( 2000 ) . TNFR-associated factor family protein expression in normal tissues and lymphoid malignancies . J Immunol vol. 165 , ( 9 ) 5084 - 5096 .
Gagro A, McCloskey N, Challa A, Holder M, Grafton G, Pound JD, Gordon J ( 2000 ) . CD5-positive and CD5-negative human B cells converge to an indistinguishable population on signalling through B-cell receptors and CD40 . Immunology vol. 101 , ( 2 ) 201 - 209 .
Zapata JM, Krajewska M, Krajewski S, Kitada S, Welsh K, Monks A, McCloskey N, Gordon J et al. ( 2000 ) . TRAF-family protein expression in normal tissues and lymphoid malignancies . BLOOD . vol. 96 , 143B - 143B .
McCloskey N, Pound JD, Holder MJ, Williams JM, Roberts LM, Lord JM, Gordon J ( 1999 ) . The extrafollicular-to-follicular transition of human B lymphocytes: induction of functional globotriaosylceramide (CD77) on high threshold occupancy of CD40 . Eur J Immunol vol. 29 , ( 10 ) 3236 - 3244 .
Goldblatt D, Miller E, McCloskey N, Cartwright K ( 1998 ) . Immunological response to conjugate vaccines in infants: follow up study . BMJ vol. 316 , ( 7144 ) 1570 - 1571 .
Goldblatt D, Miller E, McCloskey N, Cartwright K ( 1998 ) . Immunological response to conjugate vaccines in infants: follow up study . BMJ-BRITISH MEDICAL JOURNAL vol. 316 , ( 7144 ) 1570 - 1571 .
McCloskey N, Turner MW, Goldblatt TD ( 1997 ) . Correlation between the avidity of mouse-human chimeric IgG subclass monoclonal antibodies measured by solid-phase elution ELISA and biospecific interaction analysis (BIA) . J Immunol Methods vol. 205 , ( 1 ) 67 - 72 .
McCloskey N, Turner MW, Steffner P, Owens R, Goldblatt D ( 1996 ) . Human constant regions influence the antibody binding characteristics of mouse-human chimeric IgG subclasses . Immunology vol. 88 , ( 2 ) 169 - 173 .