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Publications:  Dr Alice Shia

Schmid P, Pinder S, Wheatley D, Zummit C, Macaskill EJ, Hu J, Price R, Bundred N et al. (2019). Interaction of PIK3CA mutation subclasses with response to preoperative treatment with the PI3K inhibitor pictilisib in patients with estrogen receptor-positive breast cancer. CANCER RESEARCH. vol. 79,
10.1158/1538-7445.SABCS18-P2-08-02
O'Leary K, Shia A, Schmid P(2017). Epigenetic Regulation of EMT in Non-Small Cell Lung Cancer. Curr Cancer Drug Targets vol. 18, (1) 89-96.
10.2174/1568009617666170203162556
Lenihan C, Bouchekioua-Bouzaghou K, Abdulghani R, Chupin J, Shia A, Schmid P (2017). CDK4/6 inhibitor resistant ER-positive cells remain dependent on estrogen signalling and retain sensitivity to endocrine therapy. CANCER RESEARCH. vol. 77,
10.1158/1538-7445.SABCS16-P3-03-12
Bouchekioua-Bouzaghou K, Lenihan C, Shia A, Wilkes E, Casado-Izquierdo P, Cutillas P, Schmid P (2016). Characterization of the mechanisms of early and later stages of resistance to the selective CDK4/6 inhibitor palbociclib. CANCER RESEARCH. vol. 76,
10.1158/1538-7445.AM2016-2819
Lenihan C, Cavicchioli F, O'Leary K, Shia A, Schmid P (2016). The role of VAV-interacting Kruppel-like factor (VIK) in resistance to palbociclib in estrogen receptor-positive breast cancer. CANCER RESEARCH. vol. 76,
10.1158/1538-7445.AM2016-2110
Schmid P, Pinder SE, Wheatley D, Macaskill J, Zammit C, Hu J, Price R, Bundred N et al.(2016). Phase II randomized preoperative window-of-opportunity study of the PI3K inhibitor pictilisib plus anastrozole compared with anastrozole alone in patients with estrogen receptor-positive breast cancer. Journal of Clinical Oncology vol. 34, (17) 1987-1994.
10.1200/JCO.2015.63.9179
https://qmro.qmul.ac.uk/xmlui/handle/123456789/14490
Lenihan C, Bouchekioua-Bouzaghou K, Shia A, Wilkes E, Casado-Izguierdo P, Cutillas P, Schmid P (2016). Characterization of resistance to the selective CDK4/6 inhibitor palbociclib in ER positive breast cancer. CANCER RESEARCH. vol. 76,
10.1158/1538-7445.SABCS15-P3-06-02
Schmid P, Pinder SE, Bundred N, Wheatley D, Macaskill J, Zammit C, Hu J, Price R et al. (2016). Transcript analysis of PI3K and immune-related genes and gene signatures in the pre- and post-treatment samples from the window of opportunity study of anastrozole and anastrozole with pictilisib (GDC-0941) in patients with HR-positive early breast cancer (OPPORTUNE study). CANCER RESEARCH. vol. 76,
10.1158/1538-7445.SABCS15-P5-13-01
O Leary K, Shia A, Cavicchioli F, Haley V, Comino A, Merlano M, Mauri F, Walter K et al.(2015). Identification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer. British Journal of Cancer
10.1038/bjc.2015.302
Schmid P, Pinder SE, Wheatley D, Macaskill J, Zammit C, Hu J, Price R, Bundred N et al. (2015). Preoperative window of opportunity study of the PI3K inhibitor pictilisib (GDC-0941) plus anastrozole vs anastrozole alone in patients with ER+, HER2-negative operable breast cancer (OPPORTUNE study). CANCER RESEARCH. vol. 75,
10.1158/1538-7445.SABCS14-S2-03
O'Leary K, Shia A, Cavicchioli F, Haley V, Comino A, Merlano M, Mauri F, Walter K et al.(2015). Identification of Endoglin as an epigenetically regulated tumour-suppressor gene in lung cancer. British Journal of Cancer vol. 113, (6) 970-978.
10.1038/bjc.2015.302
Progatzky F, Sangha NJ, Yoshida N, McBrien M, Cheung J, Shia A, Scott J, Marchesi JR et al. (2014). Intestinal inflammation induced by dietary cholesterol in Zebrafish. IMMUNOLOGY. vol. 143, 27-28.
Progatzky F, Sangha NJ, Yoshida N, McBrien M, Cheung J, Shia A, Scott J, Marchesi JR et al.(2014). Dietary cholesterol directly induces acute inflammasome-dependent intestinal inflammation. Nature communications vol. 5,
10.1038/ncomms6864
Denne L, Shia A, Komulainen E, Haley V, Lenihan C, Cavicchioli F, O'Leary K, Schmid P(2013). The potent anti-androgen enzalutamide demonstrates broad anti-tumour activity across all androgen receptor-positive triple-negative breast cancer subtypes. CANCER RESEARCH vol. 73,
10.1158/0008-5472.SABCS13-P2-09-05
Cavicchioli F, Shia A, O'Leary K, Haley V, Crook T, Thompson AM, Lackner M, Jones LJ et al. (2013). Sensitivity to glutamine deprivation is dependent on the interplay between epigenetic regulation of Glutamine synthetase (Glul) and induction of autophagy. EUROPEAN JOURNAL OF CANCER. vol. 49, S141-S141.
Haley V, Cavicchioli F, Shia A, O'Leary K, Balakrishnan L, Lo Nigro C, Schmid R (2013). miRNAs in resistance to lapatinib in HER2-positive breast cancer. EUROPEAN JOURNAL OF CANCER. vol. 49, S121-S121.
Cavicchioli F, Shia A, O'Leary K, Haley V, Crook TR, Thompson AM, Lackner M, Lo NC et al. (2012). Epigenetic silencing of glutamine synthetase (Glul) defines glutamine depletion therapy. CANCER RESEARCH. vol. 72,
10.1158/0008-5472.SABCS12-P4-06-10
Lara R, Mauri FA, Taylor H, Derua R, Shia A, Gray C, Nicols A, Shiner RJ et al.(2011). An siRNA screen identifies RSK1 as a key modulator of lung cancer metastasis. ONCOGENE vol. 30, (32) 3513-3521.
10.1038/onc.2011.61
Shia AKH, Glittenberg M, Thompson G, Weber AN, Reichhart JM, Ligoxygakis P(2009). Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes. Journal of Cell Science vol. 122, (24) 4505-4515.
10.1242/jcs.049155
Shia AKH, Glittenberg M, Thompson G, Weber AN, Reichhart J-M, Ligoxygakis P(2009). Toll-dependent antimicrobial responses in Drosophila larval fat body require Spätzle secreted by haemocytes. J Cell Sci vol. 122, (Pt 24) 4505-4515.
10.1242/jcs.049155
Shia AKH, Gan GG, Jairaman S, Peh SC(2005). High frequency of germinal centre derivation in diffuse large B cell lymphoma from Asian patients. Journal of Clinical Pathology vol. 58, (9) 962-967.
10.1136/jcp.2004.022624
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