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  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Sergey Krysov

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Edwards K, Manoussaka M, Sayed U, Tsertsvadze T, Deyn LD, Nathwani A, Gribben JG, Krysov S et al. ( 2024 ) . MD-1 downregulation is associated with reduced cell surface CD180 expression in CLL . Leukemia Research vol. 143 ,
Repschlaeger C, Odabashian M, Spada F, Almutairi Z, Gribben JG, Forconi F, Sayan E, Alves AC et al. ( 2022 ) . EMT-like Activation in CLL Provides Novel Therapeutic Target . Blood . vol. 140 , 12375 - 12376 .
Edwards K, Zaitseva K, Sayed U, Volpi EV, Nathwani A, Gribben JG, Lydyard P, Krysov S et al. ( 2021 ) . Expression patterns of CD180 in the lymph nodes of patients with chronic lymphocytic leukaemia . British Journal of Haematology vol. 195 , ( 2 ) e131 - e134 .
Krysov S, Odabashian M, Carlotti E, Araf S, Okosun J, Spada F, Gribben J, Forconi F et al. ( 2020 ) . IGHV sequencing reveals acquired N-glycosylation sites as a clonal and stable event during follicular lymphoma evolution . Blood vol. 135 , ( 11 ) 834 - 844 .
Odabashian M, Carlotti E, Araf S, Okosun J, Forconi F, Stevenson FK, Gribben JG, Calaminici M et al. ( 2018 ) . Immunoglobulin Variable Region Gene Sequences Reveal N-Glycosylation Motifs As an Early and Stable Event in Follicular Lymphoma Pathology . Blood . Conference: Search Results Web results ASH Meeting on Lymphoma Biology vol. 132 , 4101 - 4101 .
Yeomans A, Lemm E, Wilmore S, Cavell BE, Valle-Argos B, Krysov S, Hidalgo MS, Leonard E et al. ( 2016 ) . PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells . Oncotarget vol. 7 , ( 46 ) 74807 - 74819 .
Yeomans A, Thirdborough SM, Valle-Argos B, Linley A, Krysov S, Hidalgo MS, Leonard E, Ishfaq M et al. ( 2015 ) . Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation . Blood vol. 127 , ( 4 ) 449 - 457 .
Oldreive CE, Skowronska A, Davies NJ, Parry H, Agathanggelou A, Krysov S, Packham G, Rudzki Z et al. ( 2015 ) . T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice . Disease Models & Mechanisms vol. 8 , ( 11 ) 1401 - 1412 .
Linley A, Krysov S, Ponzoni M, Johnson PW, Packham G, Stevenson FK ( 2015 ) . Lectin binding to surface Ig variable regions provides a universal persistent activating signal for follicular lymphoma cells . Blood vol. 126 , ( 16 ) 1902 - 1910 .
Schneider D, Dühren-von Minden M, Alkhatib A, Setz C, van Bergen CAM, Benkißer-Petersen M, Wilhelm I, Villringer S et al. ( 2015 ) . Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma . Blood vol. 125 , ( 21 ) 3287 - 3296 .
Krysov S, Steele AJ, Coelho V, Linley A, Sanchez Hidalgo M, Carter M, Potter KN, Kennedy B et al. ( 2014 ) . Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK . Blood vol. 124 , ( 20 ) 3101 - 3109 .
Packham G, Krysov S, Allen A, Savelyeva N, Steele AJ, Forconi F, Stevenson FK ( 2014 ) . The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy . Haematologica vol. 99 , ( 7 ) 1138 - 1148 .
Coelho V, Krysov S, Steele A, Hidalgo MS, Johnson PW, Chana PS, Packham G, Stevenson FK et al. ( 2013 ) . Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function . Blood vol. 122 , ( 15 ) 2664 - 2672 .
Paterson A, Mockridge CI, Adams JE, Krysov S, Potter KN, Duncombe AS, Cook SJ, Stevenson FK et al. ( 2011 ) . Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia . Blood vol. 119 , ( 7 ) 1726 - 1736 .
Krysov S, Dias S, Paterson A, Mockridge CI, Potter KN, Smith K-A, Ashton-Key M, Stevenson FK et al. ( 2011 ) . Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells . Blood vol. 119 , ( 1 ) 170 - 179 .
Stevenson FK, Krysov S, Davies AJ, Steele AJ, Packham G ( 2011 ) . B-cell receptor signaling in chronic lymphocytic leukemia . Blood vol. 118 , ( 16 ) 4313 - 4320 .
Coelho V, Krysov S, Ghaemmaghami AM, Emara M, Potter KN, Johnson P, Packham G, Martinez-Pomares L et al. ( 2010 ) . Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins . Proceedings of the National Academy of Sciences of the United States of America vol. 107 , ( 43 ) 18587 - 18592 .
Krysov S, Potter KN, Mockridge CI, Coelho V, Wheatley I, Packham G, Stevenson FK ( 2010 ) . Surface IgM of CLL cells displays unusual glycans indicative of engagement of antigen in vivo . Blood vol. 115 , ( 21 ) 4198 - 4205 .
Ivanov A, Krysov S, Cragg MS, Illidge T ( 2008 ) . Radiation Therapy with Tositumomab (B1) Anti-CD20 Monoclonal Antibody Initiates Extracellular Signal-Regulated Kinase/Mitogen-Activated Protein Kinase–Dependent Cell Death that Overcomes Resistance to Apoptosis . Clinical Cancer Research vol. 14 , ( 15 ) 4925 - 4934 .
Krysov SV, Rowley TF, Al-Shamkhani A ( 2007 ) . Inhibition of p38 mitogen-activated protein kinase unmasks a CD30-triggered apoptotic pathway in anaplastic large cell lymphoma cells . Molecular Cancer Therapeutics vol. 6 , ( 2 ) 703 - 711 .
Sennikov SV, Injelevskaya TV, Krysov SV, Silkov AN, Kovinev IB, Dyachkova NJ, Zenkov AN, Loseva MI et al. ( 2004 ) . Production of hemo- and immunoregulatory cytokines by erythroblast antigen+ and glycophorin A+ cells from human bone marrow . BMC Molecular and Cell Biology vol. 5 , ( 1 )
Sennikov SV, Krysov SV, Injelevskaya TV, Silkov AN, Grishina LV, Kozlov VA ( 2003 ) . Quantitative analysis of human immunoregulatory cytokines by electrochemiluminescence method . Journal of Immunological Methods vol. 275 , ( 1-2 ) 81 - 88 .
Sennikov SV, Krysov SV, Silkov AN, Injelevskaya TV, Kozlov VA ( 2002 ) . Production of IL-10, TNF-alpha, IFN-gamma, TGF-beta1 by different populations of erythroid cells derived from human embryonal liver . Cytokine vol. 17 , ( 4 ) 221 - 225 .
Kuramshin DK, Tolokonskaia NP, Kozhevnikov VS, Mal'tinskiĭ ML, Krysov SV, Sennikov SV, Kozlov VA ( 2002 ) . Lymphocyte subpopulations and level of the proinflammatory cytokines in the blood of patients with hepatitis C and with combined variant of hepatitis C and B . Zhurnal Mikrobiologii Epidemiologii i Immunobiologii ( 1 ) 42 - 48 .
Sennikov SV, Eremina LV, Injelevskaya TV, Krysov SV, Silkov AN, Kozlov VA ( 2001 ) . Cytokine-Synthesizing Activity of Erythroid Cells . Russian Journal of Immunology vol. 6 , ( 2 ) 193 - 202 .
Kuramshin DK, Tolokonskaia NP, Silkov AN, Krysov SV, Sennikov SV, Kozlov VA ( 2001 ) . Level of Tx1- and Tx2-type cytokines in blood sera of hepatitis C patients . Zhurnal Mikrobiologii Epidemiologii i Immunobiologii ( 1 ) 57 - 61 .
Sennikov SV, Krysov SV, Injelevskaya TV, Silkov AN, Kozlov VA ( 2001 ) . Production of cytokines by immature erythroid cells derived from human embryonic liver . European Cytokine Network vol. 12 , ( 2 ) 274 - 279 .
Krysov SV, Kuramshin DX, Silkov SA, Sennikov SV, Kozlov VA ( 2000 ) . The use of electrochemoluminescent method for detection of cytokines in various media . Laboratornoe Delo ( 12 ) 39 - 43 .
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