Publications:  Dr Sergey Krysov

Krysov S, Odabashian M, Carlotti E, Araf S, Okosun J, Spada F, Gribben J, Forconi F et al.(2020). IGHV sequencing reveals acquired N-glycosylation sites as a clonal and stable event during follicular lymphoma evolution. Blood vol. 135, (11) 834-844.

Yeomans A, Lemm E, Wilmore S, Cavell BE, Valle-Argos B, Krysov S, Hidalgo MS, Leonard E et al.(2016). PEITC-mediated inhibition of mRNA translation is associated with both inhibition of mTORC1 and increased eIF2α phosphorylation in established cell lines and primary human leukemia cells. Oncotarget vol. 7, (46) 74807-74819.

Yeomans A, Thirdborough SM, Valle-Argos B, Linley A, Krysov S, Hidalgo MS, Leonard E, Ishfaq M et al.(2016). Engagement of the B-cell receptor of chronic lymphocytic leukemia cells drives global and MYC-specific mRNA translation. Blood vol. 127, (4) 449-457.

Linley A, Krysov S, Ponzoni M, Johnson PW, Packham G, Stevenson FK(2015). Lectin binding to surface Ig variable regions provides a universal persistent activating signal for follicular lymphoma cells. Blood vol. 126, (16) 1902-1910.

Oldreive CE, Skowronska A, Davies NJ, Parry H, Agathanggelou A, Krysov S, Packham G, Rudzki Z et al.(2015). T-cell number and subtype influence the disease course of primary chronic lymphocytic leukaemia xenografts in alymphoid mice. Disease Models & Mechanisms vol. 8, (11) 1401-1412.

Schneider D, Dühren-von Minden M, Alkhatib A, Setz C, van Bergen CAM, Benkißer-Petersen M, Wilhelm I, Villringer S et al.(2015). Lectins from opportunistic bacteria interact with acquired variable-region glycans of surface immunoglobulin in follicular lymphoma. Blood vol. 125, (21) 3287-3296.

Krysov S, Steele AJ, Coelho V, Linley A, Hidalgo MS, Carter M, Potter KN, Kennedy B et al.(2014). Stimulation of surface IgM of chronic lymphocytic leukemia cells induces an unfolded protein response dependent on BTK and SYK. Blood vol. 124, (20) 3101-3109.

Packham G, Krysov S, Allen A, Savelyeva N, Steele AJ, Forconi F, Stevenson FK(2014). The outcome of B-cell receptor signaling in chronic lymphocytic leukemia: proliferation or anergy. Haematologica vol. 99, (7) 1138-1148.

Coelho V, Krysov S, Steele A, Sanchez Hidalgo M, Johnson PW, Chana PS, Packham G, Stevenson FK et al.(2013). Identification in CLL of circulating intraclonal subgroups with varying B-cell receptor expression and function. Blood vol. 122, (15) 2664-2672.

Paterson A, Mockridge CI, Adams JE, Krysov S, Potter KN, Duncombe AS, Cook SJ, Stevenson FK et al.(2012). Mechanisms and clinical significance of BIM phosphorylation in chronic lymphocytic leukemia. Blood vol. 119, (7) 1726-1736.

Krysov S, Dias S, Paterson A, Mockridge CI, Potter KN, Smith K-A, Ashton-Key M, Stevenson FK et al.(2012). Surface IgM stimulation induces MEK1/2-dependent MYC expression in chronic lymphocytic leukemia cells. Blood vol. 119, (1) 170-179.

Stevenson FK, Krysov S, Davies AJ, Steele AJ, Packham G(2011). B-cell receptor signaling in chronic lymphocytic leukemia. Blood vol. 118, (16) 4313-4320.

Coelho V, Krysov S, Ghaemmaghami AM, Emara M, Potter KN, Johnson P, Packham G, Martinez-Pomares L et al.(2010). Glycosylation of surface Ig creates a functional bridge between human follicular lymphoma and microenvironmental lectins. Proceedings of the National Academy of Sciences vol. 107, (43) 18587-18592.

Krysov S, Potter KN, Mockridge CI, Coelho V, Wheatley I, Packham G, Stevenson FK(2010). Surface IgM of CLL cells displays unusual glycans indicative of engagement of antigen in vivo. Blood vol. 115, (21) 4198-4205.

Ivanov A, Krysov S, Cragg MS, Illidge T(2008). Radiation therapy with tositumomab (B1) anti-CD20 monoclonal antibody initiates extracellular signal-regulated kinase/mitogen-activated protein kinase-dependent cell death that overcomes resistance to apoptosis. Clinical Cancer Research vol. 14, (15)

Krysov SV, Rowley TF, Al-Shamkhani A(2007). Inhibition of p38 mitogen-activated protein kinase unmasks a CD30-triggered apoptotic pathway in anaplastic large cell lymphoma cells. Molecular Cancer Therapeutics vol. 6, (2) 703-711.