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Research

Publications: Mr Edward Carter

Coetzee AS, Carter EP, Rodríguez-Fernández L, Heward J, Wang Q, Karim SA, Boughetane L, Milton C et al. ( 2023 ) . Correction: Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1 (Oncogene, (2023), 42, 7, (491-500), 10.1038/s41388-022-02513-5) . Oncogene vol. 42 , ( 7 )
Coetzee AS, Carter EP, Rodríguez-Fernández L, Heward J, Wang Q, Karim SA, Boughetane L, Milton C et al. ( 2023 ) . Nuclear FGFR1 promotes pancreatic stellate cell-driven invasion through up-regulation of Neuregulin 1 . Oncogene vol. 42 , ( 7 ) 491 - 500 .
Gibson SV, Roozitalab RM, Allen MD, Jones JL, Carter EP, Grose RP ( 2023 ) . Everybody needs good neighbours: the progressive DCIS microenvironment . Trends Cancer
Hayat A, Carter EP, King HW, Ors A, Doe A, Teijeiro SA, Charrot S, Godinho S et al. ( 2023 ) . Low HER2 expression in normal breast epithelium enables dedifferentiation and malignant transformation via chromatin opening . Disease models & mechanisms vol. 16 , ( 2 )
Bort ET, Joseph M, Wang Q, Carter E, Roth N, Gibson J, Samadi A, Kocher H et al. ( 2022 ) . Extracellular ATP drives pancreatic cancer cell invasion via purinergic receptor-integrin interactions .
Carter E, Yoneten K, Gavara N, Tyler E, Gauthier V, Murray E, Cameron A, Pearce O et al. ( 2022 ) . Opposing roles for ADAMTS2 and ADAMTS14 in myofibroblast differentiation and function .
Hayat A, Carter EP, King HW, Ors A, Doe A, Teijeiro SA, Charrot S, Godinho S et al. ( 2022 ) . Low HER2 enables dedifferentiation and transformation of normal breast epithelial cells via chromatin opening .
Newport E, Pedrosa AR, Lees D, Dukinfield M, Carter E, Gomez-Escudero J, Casado P, Rajeeve V et al. ( 2022 ) . Elucidating the role of the kinase activity of endothelial cell focal adhesion kinase in angiocrine signalling and tumour growth . Journal of Pathology vol. 256 , ( 2 ) 235 - 247 .
Murray ER, Menezes S, Henry JC, Williams JL, Alba-Castellón L, Baskaran P, Quétier I, Desai A et al. ( 2022 ) . Disruption of pancreatic stellate cell myofibroblast phenotype promotes pancreatic tumor invasion . Cell Reports vol. 38 , ( 4 )
Carter EP, Roozitalab R, Gibson SV, Grose RP ( 2021 ) . Tumour microenvironment 3D-modelling: simplicity to complexity and back again . Trends in Cancer vol. 7 , ( 11 ) 1033 - 1046 .
Adams SD, Csere J, D'angelo G, Carter EP, Romao M, Arnandis T, Dodel M, Kocher HM et al. ( 2021 ) . Centrosome amplification mediates small extracellular vesicle secretion via lysosome disruption . Current Biology vol. 31 , ( 7 ) 1403 - 1416.e7 .
Carter EP, Coetzee AS, Bort ET, Wang Q, Kocher HM, Grose RP ( 2021 ) . Dissecting fgf signalling to target cellular crosstalk in pancreatic cancer . Cells vol. 10 , ( 4 )
Adams S, Csere J, D’angelo G, Carter E, Arnandis T, Dodel M, Kocher H, Grose R et al. ( 2020 ) . Centrosome amplification mediates small extracellular vesicles secretion via lysosome disruption .
Wilcz-Villega E, Carter E, Ironside A, Xu R, Mataloni I, Holdsworth J, Jones W, Moreno Béjar R et al. ( 2020 ) . Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway . EMBO Molecular Medicine vol. 12 , ( 2 )
Coetzee A, Carter E, Heward J, Mardakheh F, Grose R, Kocher H ( 2019 ) . Abstract 5170: Targeting FGFR signaling to disrupt cellular cross-talk in pancreatic cancer . Cancer Research . vol. 79 , 5170 - 5170 .
Pedrosa A-R, BODRUG N, Gomez-Escudero J, Carter EP, Reynolds LE, Georgiou PN, Fernandez I, Lees DM et al. ( 2019 ) . Tumour angiogenesis is differentially regulated by endothelial cell Focal Adhesion Kinase tyrosine-397 and -861 phosphorylation . Cancer Research
Fearon AE, Carter EP, Clayton NS, Wilkes EH, Baker AM, Kapitonova E, Bakhouche BA, Tanner Y et al. ( 2018 ) . PHLDA1 Mediates Drug Resistance in Receptor Tyrosine Kinase-Driven Cancer . Cell Reports vol. 22 , ( 9 ) 2469 - 2481 .
Clayton NS, Wilson AS, Laurent EP, Grose RP, Carter EP ( 2017 ) . Fibroblast growth factor-mediated crosstalk in cancer etiology and treatment . Dev Dyn vol. 246 , ( 7 ) 493 - 501 .
Carter EP, Gopsill JA, Gomm JJ, Jones JL, Grose RP ( 2017 ) . A 3D in vitro model of the human breast duct: A method to unravel myoepithelial-luminal interactions in the progression of breast cancer . Breast Cancer Research vol. 19 , ( 1 )
Carter E, Gomm JJ, Jones LJ, Grose RP ( 2016 ) . A 3D in vitro model of the human breast duct: unravelling myoepithelial-luminal interactions in breast cancer . Breast Cancer Research and Treatment . Conference: UK Breast Cancer Research Symposium 2016 vol. 159 , 187 - 188 .
Carter EP, Fearon AE, Grose RP ( 2015 ) . Careless talk costs lives: Fibroblast growth factor receptor signalling and the consequences of pathway malfunction . Trends in Cell Biology vol. 25 , ( 4 ) 221 - 233 .
Cravo AS, Carter E, Erkan M, Harvey E, Furutani-Seiki M, Mrsny R ( 2015 ) . Hippo pathway elements Co-localize with Occludin: A possible sensor system in pancreatic epithelial cells . Tissue Barriers vol. 3 , ( 3 )
Carter E, Miron-Buchacra G, Goldoni S, Danahay H, Westwick J, Watson ML, Tosh D, Ward SG ( 2014 ) . Phosphoinositide 3-kinase alpha-dependent regulation of branching morphogenesis in murine embryonic lung: evidence for a role in determining morphogenic properties of FGF7 . PLoS One vol. 9 , ( 12 )
Carter E, Lau CY, Tosh D, Ward SG, Mrsny RJ ( 2013 ) . Cell penetrating peptides fail to induce an innate immune response in epithelial cells in vitro: implications for continued therapeutic use . Eur J Pharm Biopharm vol. 85 , ( 1 ) 12 - 19 .
Foster JG, Carter E, Kilty I, MacKenzie AB, Ward SG ( 2013 ) . Mitochondrial superoxide generation enhances P2X7R-mediated loss of cell surface CD62L on naive human CD4+ T lymphocytes . J Immunol vol. 190 , ( 4 ) 1551 - 1559 .
Foster JG, Blunt MD, Carter E, Ward SG ( 2012 ) . Inhibition of PI3K signaling spurs new therapeutic opportunities in inflammatory/autoimmune diseases and hematological malignancies . Pharmacol Rev vol. 64 , ( 4 ) 1027 - 1054 .