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  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Bela Wrench

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Di Mambro A, Arroyo-Berdugo Y, Fioretti T, Randles M, Cozzuto L, Rajeeve V, Cevenini A, Austin MJ et al. ( 2023 ) . SET-PP2A complex as a new therapeutic target in KMT2A (MLL) rearranged AML . Oncogene vol. 42 , ( 50 ) 3670 - 3683 .
Creasey T, Barretta E, Ryan SL, Butler E, Kirkwood AA, Leongamornlert D, Papaemmanuil E, Patrick P et al. ( 2021 ) . Genetic and genomic analysis of acute lymphoblastic leukaemia in older adults reveals a distinct profile of abnormalities: analysis of 210 patients from the UKALL14 and UKALL60+ clinical trials . Haematologica vol. 107 , ( 9 ) 2051 - 2063 .
Heydt Q, Xintaropoulou C, Clear A, Austin M, Pislariu I, Miraki-Moud F, Cutillas P, Korfi K et al. ( 2021 ) . Adipocytes disrupt the translational programme of acute lymphoblastic leukaemia to favour tumour survival and persistence . Nature Communications
Aries JA, Davies JK, Auer RL, Hallam SL, Montoto S, Smith M, Sevillano B, Foggo V et al. ( 2020 ) . Clinical Outcome of Coronavirus Disease 2019 in Haemato-oncology Patients . British Journal of Haematology
WRENCH BR ( 2017 ) . Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukemia . Nature Communications vol. 7 , Article 13331 ,
WRENCH BR ( 2016 ) . Pegylated-asparaginase during induction therapy for adult acute lymphoblastic leukaemia: toxicity data from the UKALL14 trial . leukaemia
Roberts KG, Payne-Turner D, McCastlain K, Gu Z, Iacobucci I, Harvey RC, Chen I-M, Valentine M et al. ( 2015 ) . High Frequency and Poor Outcome of Ph-like Acute Lymphoblastic Leukemia in Adults . Blood . vol. 126 ,
Dey A, Zhang Y, Castleton AZ, Bailey K, Beaton B, Patel B, Fielding AK ( 2015 ) . The Role of Neutrophils in Measles Virus–mediated Oncolysis Differs Between B-cell Malignancies and Is Not Always Enhanced by GCSF . Molecular Therapy vol. 24 , ( 1 ) 184 - 192 .
Patel B, Dey A, Castleton AZ, Schwab C, Samuel E, Sivakumaran J, Beaton B, Zareian N et al. ( 2014 ) . Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology . Blood vol. 124 , ( 1 ) 96 - 105 .
Castleton A, Dey A, Beaton B, Patel B, Aucher A, Davis DM, Fielding AK ( 2013 ) . Human mesenchymal stromal cells deliver systemic oncolytic measles virus to treat acute lymphoblastic leukemia in the presence of humoral immunity . Blood vol. 123 , ( 9 ) 1327 - 1335 .
Fielding AK, Rowe JM, Buck G, Foroni L, Gerrard G, Litzow MR, Lazarus H, Luger SM et al. ( 2013 ) . UKALLXII/ECOG2993: addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia . Blood vol. 123 , ( 6 ) 843 - 850 .
Moorman AV, Schwab C, Ensor HM, Russell LJ, Morrison H, Jones L, Masic D, Patel B et al. ( 2012 ) . IGH@ Translocations, CRLF2 Deregulation, and Microdeletions in Adolescents and Adults With Acute Lymphoblastic Leukemia . Journal of Clinical Oncology vol. 30 , ( 25 ) 3100 - 3108 .
Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK ( 2012 ) . Attenuated, Oncolytic, but Not Wild-Type Measles Virus Infection Has Pleiotropic Effects on Human Neutrophil Function . The Journal of Immunology vol. 188 , ( 3 ) 1002 - 1010 .
Patel B, Dey A, Ghorani E, Kumar S, Malam Y, Rai L, Steele AJ, Thomson J et al. ( 2011 ) . Differential Cytopathology and Kinetics of Measles Oncolysis in Two Primary B-cell Malignancies Provides Mechanistic Insights . Molecular Therapy vol. 19 , ( 6 ) 1034 - 1040 .
Patel B, Rai L, Buck G, Richards SM, Mortuza Y, Mitchell W, Gerrard G, Moorman AV et al. ( 2009 ) . Minimal residual disease is a significant predictor of treatment failure in non T‐lineage adult acute lymphoblastic leukaemia: final results of the international trial UKALL XII/ECOG2993 . British Journal of Haematology vol. 148 , ( 1 ) 80 - 89 .
Patel B, Kirkland KE, Szydlo R, Pearce RM, Clark RE, Craddock C, Liakopoulou E, Fielding AK et al. ( 2009 ) . Favorable outcomes with alemtuzumab-conditioned unrelated donor stem cell transplantation in adults with high-risk Philadelphia chromosome-negative acute lymphoblastic leukemia in first complete remission . Haematologica vol. 94 , ( 10 ) 1399 - 1406 .
Mansour MR, Duke V, Foroni L, Patel B, Allen CG, Ancliff PJ, Gale RE, Linch DC ( 2007 ) . Notch-1 Mutations Are Secondary Events in Some Patients with T-Cell Acute Lymphoblastic Leukemia . Clinical Cancer Research vol. 13 , ( 23 ) 6964 - 6969 .
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