Publications:  Dr Bela Wrench

WRENCH BR(2017). Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukemia. Nature Communications vol. 7, Article 13331,

WRENCH BR(2016). Pegylated-asparaginase during induction therapy for adult acute lymphoblastic leukaemia: toxicity data from the UKALL14 trial. leukaemia

Dey A, Zhang Y, Castleton AZ, Bailey K, Beaton B, Patel B, Fielding AK(2016). The role of neutrophils in measles virus-mediated oncolysis differs between B-cell malignancies and is not always enhanced by GCSF. Molecular Therapy vol. 24, (1) 184-192.

Roberts KG, Payne-Turner D, McCastlain K, Gu Z, Iacobucci I, Harvey RC, Chen I-M, Valentine M et al. (2015). High Frequency and Poor Outcome of Ph-like Acute Lymphoblastic Leukemia in Adults. BLOOD. vol. 126,

Patel B, Dey A, Castleton AZ, Schwab C, Samuel E, Sivakumaran J, Beaton B, Zareian N et al.(2014). Mouse xenograft modeling of human adult acute lymphoblastic leukemia provides mechanistic insights into adult LIC biology. Blood vol. 124, (1) 96-105.

Castleton A, Dey A, Beaton B, Patel B, Aucher A, Davis DM, Fielding AK(2014). Human mesenchymal stromal cells deliver systemic oncolytic measles virus to treat acute lymphoblastic leukemia in the presence of humoral immunity. Blood vol. 123, (9) 1327-1335.

Fielding AK, Rowe JM, Buck G, Foroni L, Gerrard G, Litzow MR, Lazarus H, Luger SM et al.(2014). UKALLXII/ECOG2993: Addition of imatinib to a standard treatment regimen enhances long-term outcomes in Philadelphia positive acute lymphoblastic leukemia. Blood vol. 123, (6) 843-850.

Moorman AV, Schwab C, Ensor HM, Russell LJ, Morrison H, Jones L, Masic D, Patel B et al.(2012). IGH@ translocations, CRLF2 deregulation, and microdeletions in adolescents and adults with acute lymphoblastic leukemia. Journal of Clinical Oncology vol. 30, (25) 3100-3108.

Zhang Y, Patel B, Dey A, Ghorani E, Rai L, Elham M, Castleton AZ, Fielding AK(2012). Attenuated, oncolytic, but not wild-type measles virus infection has pleiotropic effects on human neutrophil function. Journal of Immunology vol. 188, (3) 1002-1010.

Patel B, Dey A, Ghorani E, Kumar S, Malam Y, Rai L, Steele AJ, Thomson J et al.(2011). Differential cytopathology and kinetics of measles oncolysis in two primary B-cell malignancies provides mechanistic insights. Molecular Therapy vol. 19, (6) 1034-1040.

Patel B, Rai L, Buck G, Richards SM, Mortuza Y, Mitchell W, Gerrard G, Moorman AV et al.(2010). Minimal residual disease is a significant predictor of treatment failure in non T-lineage adult acute lymphoblastic leukaemia: Final results of the international trial UKALL XII/ECOG2993. British Journal of Haematology vol. 148, (1) 80-89.

Patel B, Kirkland KE, Szydlo R, Pearce RM, Clark RE, Craddock C, Liakopoulou E, Fielding AK et al.(2009). Favorable outcomes with alemtuzumab-conditioned unrelated donor stem cell transplantation in adults with high-risk Philadelphia chromosome-negative acute lymphoblastic leukemia in first complete remission. Haematologica vol. 94, (10) 1399-1406.

Mansour MR, Duke V, Foroni L, Patel B, Allen CG, Ancliff PJ, Gale RE, Linch DC(2007). Notch-1 mutations are secondary events in some patients with T-cell acute lymphoblastic leukemia. Clinical Cancer Research vol. 13, (23) 6964-6969.