Publications:  Dr Eirini Marouli

Marouli E, Kus A, Del Greco M F, Chaker L, Peeters R, Teumer A, Deloukas P, Medici M(2020). Thyroid Function Affects the Risk of Stroke via Atrial Fibrillation: A Mendelian Randomization Study. The Journal of clinical endocrinology and metabolism vol. 105, (8)

Marouli E, Del Greco MF, Astley CM, Yang J, Ahmad S, Berndt SI, Caulfield MJ, Evangelou E et al.(2019). Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease. Communications Biology vol. 2, (1)

Ng N, Willems SM, Fernandez J, Fine RS, Wheeler E, Wessel J, Kitajima H, Marenne G et al.(2019). Tissue-Specific Alteration of Metabolic Pathways Influences Glycemic Regulation.

Huang T, Wang T, Zheng Y, Ellervik C, Li X, Gao M, Fang Z, Chai JF et al.(2019). Association of Birth Weight With Type 2 Diabetes and Glycemic Traits: A Mendelian Randomization Study. JAMA network open vol. 2, (9) e1910915-e1910915.

Murphy AM, Smith CE, Murphy LM, Follis JL, Tanaka T, Richardson K, Noordam R, Lemaitre RN et al.(2019). Potential Interplay between Dietary Saturated Fats and Genetic Variants of the NLRP3 Inflammasome to Modulate Insulin Resistance and Diabetes Risk: Insights from a Meta-Analysis of 19 005 Individuals. Molecular Nutrition and Food Research vol. 63, (22)

Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2019). Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity (Nature Genetics, (2018), 50, 1, (26-41), 10.1038/s41588-017-0011-x). Nature Genetics vol. 51, (7) 1191-1192.

Huang T, Sun D, Heianza Y, Bergholdt HKM, Gao M, Fang Z, Ding M, Frazier-Wood AC et al.(2019). Dairy intake and body composition and cardiometabolic traits among adults: Mendelian randomization analysis of 182041 individuals from 18 studies. Clinical Chemistry vol. 65, (6) 751-760.

Marouli E, Del Greco MF, Astley CM, Yang J, Ahmad S, Berndt SI, Caulfield MJ, Evangelou E et al.(2019). Mendelian randomisation analyses find pulmonary factors mediate the effect of height on coronary artery disease. Commun Biol vol. 2, (1)

Xie T, Gorenjak V, Stathopoulou MG, Dadé S, Marouli E, Masson C, Murray H, Lamont J et al.(2019). Epigenome-wide association study (EWAS) of blood lipids in healthy population from STANISLAS family study (SFS). International Journal of Molecular Sciences vol. 20, (5)

Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL et al.(2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nature Genetics vol. 51, (3) 452-469.

Pulit SL, Stoneman C, Morris AP, Wood AR, Glastonbury CA, Tyrrell J, Yengo L, Ferreira T et al.(2019). Meta-Analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestry. Human Molecular Genetics vol. 28, (1) 166-174.

Erzurumluoglu AM, Liu M, Jackson VE, Barnes DR, Datta G, Melbourne CA, Young R, Batini C et al.(2019). Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci. Molecular Psychiatry

Brazel DM, Jiang Y, Hughey JM, Turcot V, Zhan X, Gong J, Batini C, Weissenkampen JD et al.(2018). Exome Chip Meta-analysis Fine Maps Causal Variants and Elucidates the Genetic Architecture of Rare Coding Variants in Smoking and Alcohol Use. Biological Psychiatry

Hackinger S, Prins B, Mamakou V, Zengini E, Marouli E, Br¿i¿ L, Serafetinidis I, Lamnissou K et al.(2018). Evidence for genetic contribution to the increased risk of type 2 diabetes in schizophrenia. Translational Psychiatry vol. 8, (1)

Mamakou V, Hackinger S, Zengini E, Tsompanaki E, Marouli E, Serafetinidis I, Prins B, Karabela A et al.(2018). Combination therapy as a potential risk factor for the development of type 2 diabetes in patients with schizophrenia: The GOMAP study. BMC Psychiatry vol. 18, (1)

Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H et al.(2018). Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes article. Nature Genetics vol. 50, (4) 559-571.

Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2018). Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nature Genetics vol. 50, (1) 26-35.

Turcot V, Lu Y, Highland HM, Schurmann C, Justice AE, Fine RS, Bradfield JP, Esko T et al.(2017). Publisher Correction: Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity. Nat Genet vol. 50, (5) 766-767.

Liu DJ, Peloso GM, Yu H, Butterworth AS, Wang X, Mahajan A, Saleheen D, Emdin C et al.(2017). Exome-wide association study of plasma lipids in >300,000 individuals. Nature Genetics vol. 49, (12) 1758-1766.

Marouli E, Kanoni S, Mamakou V, Hackinger S, Southam L, Prins B, Rentari A, Dimitriou M et al.(2017). Evaluating the glucose raising effect of established loci via a genetic risk score. PLoS One vol. 12, (11) Article 0186669, e0186669-e0186669.

Nelson CP, Goel A, Butterworth AS, Kanoni S, Webb TR, Marouli E, Zeng L, Ntalla I et al.(2017). Association analyses based on false discovery rate implicate new loci for coronary artery disease. Nature Genetics vol. 49, (9) 1385-1391.

Saleheen D, Zhao W, Young R, Nelson CP, Ho W, Ferguson JF, Rasheed A, Ou K et al.(2017). Loss of Cardioprotective Effects at the ADAMTS7 Locus as a Result of Gene-Smoking Interactions. Circulation vol. 135, (24) 2336-2353.

Li M, Li Y, Weeks O, Mijatovic V, Teumer A, Huffman JE, Tromp G, Fuchsberger C et al.(2017). SOS2 and ACP1 Loci Identified through Large-Scale Exome Chip Analysis Regulate Kidney Development and Function. Journal of the American Society of Nephrology vol. 28, (3) 981-994.

Webb TR, Erdmann J, Stirrups KE, Stitziel NO, Masca NGD, Jansen H, Kanoni S, Nelson CP et al.(2017). Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease. J Am Coll Cardiol vol. 69, (7) 823-836.

Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y et al.(2017). Rare and low-frequency coding variants alter human adult height. Nature vol. 542, (7640) 186-190.

Loley C, Alver M, Assimes TL, Bjonnes A, Goel A, Gustafsson S, Hernesniemi J, Hopewell JC et al.(2016). No Association of Coronary Artery Disease with X-Chromosomal Variants in Comprehensive International Meta-Analysis. Sci Rep vol. 6, 35278-35278.

MUNROE PB(2016). Trans-ancestry meta-analyses identify novel rare and common variants associated with blood pressure and hypertension. Nature Genetics

MUNROE PB(2016). The genetics of blood pressure regulation and its target organs from association studies in 342,415 individuals. Nature Genetics

Agiannitopoulos K, Bakalgianni A, Marouli E, Zormpa I, Manginas A, Papamenzelopoulos S, Lamnissou K(2016). Gender Specificity of a Genetic Variant of Androgen Receptor and Risk of Coronary Artery Disease. Journal of Clinical Laboratory Analysis vol. 30, (3) 204-207.

Stitziel NO, Stirrups KE, Masca NGD, Erdmann J, Ferrario PG, König IR, Weeke PE, Webb TR et al.(2016). Coding variation in ANGPTL4, LPL, and SVEP1 and the risk of coronary disease. New England Journal of Medicine vol. 374, (12) 1134-1144.

Marouli E, Kanoni S, Dimitriou M, Kolovou G, Deloukas P, Dedoussis G(2016). Lifestyle may modify the glucose-raising effect of genetic loci. A study in the Greek population. Nutrition, Metabolism and Cardiovascular Diseases vol. 26, (3) 201-206.

Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert MF et al.(2015). Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nature Communications vol. 6,