Publications:  Dr Donato Iacovazzo

Pepe S, Korbonits M, Iacovazzo D(2019). Germline and mosaic mutations causing pituitary tumours: genetic and molecular aspects. J Endocrinol vol. 240, (2) R21-R45.

Caimari F, Hernández-Ramírez LC, Dang MN, Gabrovska P, Iacovazzo D, Stals K, Ellard S, Korbonits M et al.(2018). Risk category system to identify pituitary adenoma patients with AIP mutations. J Med Genet vol. 55, (4) 254-260.

Imran SA, Aldahmani KA, Penney L, Croul SE, Clarke DB, Collier DM, Iacovazzo D, Korbonits M(2018). Unusual AIP mutation and phenocopy in the family of a young patient with acromegalic gigantism. Endocrinol Diabetes Metab Case Rep vol. 2018,

Iacovazzo D, Flanagan SE, Walker E, Quezado R, de Sousa Barros FA, Caswell R, Johnson MB, Wakeling M et al.(2018). MAFA missense mutation causes familial insulinomatosis and diabetes mellitus. Proc Natl Acad Sci U S A vol. 115, (5) 1027-1032.

Salvatori R, Radian S, Diekmann Y, Iacovazzo D, David A, Gabrovska P, Grassi G, Bussell A-M et al.(2017). In-frame seven amino-acid duplication in AIP arose over the last 3000 years, disrupts protein interaction and stability and is associated with gigantism. Eur J Endocrinol vol. 177, (3) 257-266.

Koehler VF, Jungheim K, Groß U, Iacovazzo D, Mann A, Korbonits M(2017). Novel Germline p.Gly42Val MEN1 Mutation in a Family with Multiple Endocrine Neoplasia Type 1 - Excellent Response of Prolactinoma to Cabergoline. Ann Clin Lab Sci vol. 47, (5) 606-610.

Kiefer FW, Winhofer Y, Iacovazzo D, Korbonits M, Wolfsberger S, Knosp E, Trautinger F, Höftberger R et al.(2017). PRKAR1A mutation causing pituitary-dependent Cushing disease in a patient with Carney complex. Eur J Endocrinol vol. 177, (2) K7-K12.

Amarawardena WKMG, Liyanarachchi KD, Newell-Price JDC, Ross RJM, Iacovazzo D, Debono M(2017). Pasireotide: successful treatment of a sparsely granulated tumour in a resistant case of acromegaly. Endocrinol Diabetes Metab Case Rep vol. 2017,

Tufton N, Ghelani R, Srirangalingam U, Kumar AV, Drake WM, Iacovazzo D, Skordilis K, Berney D et al.(2017). SDHA mutated paragangliomas may be at high risk of metastasis. Endocr Relat Cancer vol. 24, (7) L43-L49.

Iacovazzo D, Hernández-Ramírez LC, Korbonits M(2017). Sporadic pituitary adenomas: the role of germline mutations and recommendations for genetic screening. Expert Review of Endocrinology and Metabolism vol. 12, (2) 143-153.

Roncaroli F, Iacovazzo D, Rodd C, Gurlek A, Dutta P, Ellard S, Sampson J, Trouillas J et al. (2017). Distinct pathological features of pituitary adenomas in patients with X-linked acrogigantism (XLAG). NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY. Conference: 118th Meeting of the British-Neuropathological-Society vol. 43, 20-20.

Iacovazzo D, Caswell R, Bunce B, Jose S, Yuan B, Hernández-Ramírez LC, Kapur S, Caimari F et al.(2016). Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study. Acta Neuropathologica Communications vol. 4, (1)

Iacovazzo D, Korbonits M(2016). Gigantism: X-linked acrogigantism and GPR101 mutations. Growth Horm IGF Res vol. 30-31, 64-69.

Ramírez-Rentería C, Hernández-Ramírez LC, Portocarrero-Ortiz L, Vargas G, Melgar V, Espinosa E, Espinosa-de-Los-Monteros AL, Sosa E et al.(2016). AIP mutations in young patients with acromegaly and the Tampico Giant: the Mexican experience. Endocrine vol. 53, (2) 402-411.

Hernández-Ramírez LC, Martucci F, Morgan RML, Trivellin G, Tilley D, Ramos-Guajardo N, Iacovazzo D, D'Acquisto F et al.(2016). Rapid Proteasomal Degradation of Mutant Proteins Is the Primary Mechanism Leading to Tumorigenesis in Patients With Missense AIP Mutations. Journal of Clinical Endocrinology and Metabolism vol. 101, (8) 3144-3154.

Rodd C, Millette M, Iacovazzo D, Stiles CE, Barry S, Evanson J, Albrecht S, Caswell R et al.(2016). Somatic GPR101 Duplication Causing X-Linked Acrogigantism (XLAG)—Diagnosis and Management. The Journal of Clinical Endocrinology & Metabolism vol. 101, (5) 1927-1930.

Koehler VF, Jungheim K, Gross U, Iacovazzo D, Korbonits M, Mann WA (2016). Novel germline p.Gly42Val MEN1 mutation in a family with multiple endocrine neoplasia type 1.

Iacovazzo D, Carlsen E, Lugli F, Chiloiro S, Piacentini S, Bianchi A, Giampietro A, Mormando M et al.(2016). Factors predicting pasireotide responsiveness in somatotroph pituitary adenomas resistant to first-generation somatostatin analogues: an immunohistochemical study. Eur J Endocrinol vol. 174, (2) 241-250.

Losa M, Bogazzi F, Cannavo S, Ceccato F, Curtò L, De Marinis L, Iacovazzo D, Lombardi G et al.(2016). Temozolomide therapy in patients with aggressive pituitary adenomas or carcinomas. Journal of Neuro-Oncology vol. 126, (3) 519-525.

Losa M, Bogazzi F, Cannavo S, Ceccato F, Curtò L, De Marinis L, Iacovazzo D, Lombardi G et al.(2016). Temozolomide therapy in patients with aggressive pituitary adenomas or carcinomas. J Neurooncol vol. 126, (3) 519-525.

Farchione A, Rufini V, Brizi MG, Iacovazzo D, Larghi A, Massara RM, Petrone G, Poscia A et al.(2016). Evaluation of the added value of diffusion-weighted imaging to conventional magnetic resonance imaging in pancreatic neuroendocrine tumors and comparison with ⁶⁸Ga-DOTANOC positron emission tomography/computed tomography. Pancreas vol. 45, (3) 345-354.

Farchione A, Rufini V, Brizi MG, Iacovazzo D, Larghi A, Massara RM, Petrone G, Poscia A et al.(2015). Evaluation of the Added Value of Diffusion-Weighted Imaging to Conventional Magnetic Resonance Imaging in Pancreatic Neuroendocrine Tumors and Comparison With 68Ga-DOTANOC Positron Emission Tomography/Computed Tomography. Pancreas

Chiloiro S, Doglietto F, Trapasso B, Iacovazzo D, Giampietro A, Di Nardo F, De Waure C, Lauriola L et al.(2015). Typical and atypical pituitary adenomas: A single-center analysis of outcome and prognosis. Neuroendocrinology vol. 101, (2) 143-150.

Iacovazzo D, Lugli F, Piacentini S, Bianchi A, Inzani F, Larocca LM, Pagano L, De Marinis L(2015). Systemic mastocytosis mimicking carcinoid syndrome. Endocrine vol. 48, (2) 718-719.

Iacovazzo D, Lugli F, Piacentini S, Bianchi A, Inzani F, Larocca LM, Pagano L, De Marinis L(2015). Systemic mastocytosis mimicking carcinoid syndrome. Endocrine vol. 48, (2) 718-719.

Iacovazzo D, De Marinis L(2015). Treatment of hyperprolactinemia in post-menopausal women: pros. Endocrine vol. 48, (1) 76-78.

Iacovazzo D, Piacentini S, Lugli F, Bianchi A, Gabrovska P, Persiani R, Rindi G, Ellard S et al. (2015). A Novel MEN1 Gene Variant in a Sporadic Case of Multiple Endocrine Neoplasia Type 1. NEUROENDOCRINOLOGY. vol. 102, 150-150.

Piacentini S, Iacovazzo D, Lugli F, Giampietro A, Bianchi A, Tartaglione L, Mormando M, Chiloiro S et al. (2015). Two Cases of Ectopic ACTH-Secreting Neoplasm of Occult Origin Becoming Overt after Bilateral Adrenalectomy. NEUROENDOCRINOLOGY. vol. 102, 153-153.

Chiloiro S, Doglietto F, Trapasso B, Iacovazzo D, Giampietro A, Di Nardo F, de Waure C, Lauriola L et al.(2015). Typical and atypical pituitary adenomas: a single-center analysis of outcome and prognosis. Neuroendocrinology vol. 101, (2) 143-150.

Iacovazzo D, Sampson JR, Morrison PJ, Foulkes W, Alevizaki M, Lugli F, Gabrovska P, Lucci-Cordisco E et al.(2014). Five families with RET-mutation negative familial medullary thyroid carcinoma: what lies beyond RET?. WIENER KLINISCHE WOCHENSCHRIFT vol. 126, S141-S142.

Chiloiro S, Bianchi A, Giampietro A, Iacovazzo D, Trapasso B, Piacentini S, Tartaglione L, Lugli F et al. (2014). Correlation Between Atypical Pituitary Adenomas and Ki-67 Li: Clinical and Prognostic Aspects. ENDOCRINE REVIEWS. vol. 35,

Bianchi A, Tartaglione L, Giampietro A, Milardi D, Angelini F, Mormando M, Lugli F, Piacentini S et al.(2014). Determinants of IGF-I Response to Rhgh in Adult Ghd: Role of GH Receptor (GHR) Isoforms. ENDOCRINE REVIEWS vol. 35, (3)

Iacovazzo D, Lugli F, Bianchi A, Capoluongo E, Lucci-Cordisco E, Persiani R, Doglietto GB, Pontecorvi A et al. (2014). Efficacy of Lanreotide Autogel in MEN1-Related Gastrinomas: A Case Series. ENDOCRINE REVIEWS. vol. 35,

Lugli F, Iacovazzo D, Lanza P, Inzani F, De Waure C, Rindi G, De Marins L (2014). Evaluation of VEGF and Endocan/Esm-1 Expression in Pnets and Correlation with Ki-67 and Prognosis. ENDOCRINE REVIEWS. vol. 35,

Iacovazzo D, Morrison PJ, Foulkes W, Ross DS, Lugli F, Gabrovska P, Lucci-Cordisco E, De Marinis L et al.(2014). Four Families with RET-Mutation Negative Familial Medullary Thyroid Carcinoma: What Lies Beyond RET?. ENDOCRINE REVIEWS vol. 35, (3)

Chiloiro S, Bianchi A, Doglietto F, de Waure C, Giampietro A, Fusco A, Iacovazzo D, Tartaglione L et al.(2014). Radically resected pituitary adenomas: prognostic role of Ki 67 labeling index in a monocentric retrospective series and literature review. Pituitary vol. 17, (3) 267-276.

Lugli F, Iacovazzo D, Piacentini S, Bianchi A, Giampietro A, Doglietto F, Balducci M, Lauriola L et al. (2014). Temozolomide: A Useful Treatment for an Aggressive ACTH Secreting Pituitary Adenoma. ENDOCRINE REVIEWS. vol. 35,

Iacovazzo D, Lugli F, Bianchi A, Capoluongo E, Lucci-Cordisco E, Persiani R, Doglietto GB, Pontecorvi A et al. (2014). Efficacy of Lanreotide Autogel in MEN1-Related Gastrinoma: A Case Series. NEUROENDOCRINOLOGY. vol. 99, 272-272.

Lugli F, Iacovazzo D, Lanza P, Inzani F, De Waure C, Rindi G, De Marinis L (2014). Evaluation of VEGF and Endocan/ESM-1 Expression in pNETs and Correlation with Ki-67 and Prognosis. NEUROENDOCRINOLOGY. vol. 99, 224-224.

Farchione A, Rufini V, Brizi MG, Lanza F, Iacovazzo D, Larghi A, Massara RM, Petrone G et al. (2014). Evaluation of the Added Value of Diffusion-Weighted Imaging to Conventional MRI in Pancreatic Neuroendocrine Tumors and Comparison with 68Ga-DOTANOC PET/CT. NEUROENDOCRINOLOGY. vol. 99, 260-260.

Iacovazzo D, De Marinis L(2014). Treatment of hyperprolactinemia in post-menopausal women: pros. Endocrine vol. 48, (1) 76-78.

Treglia G, Mormando M, Iacovazzo D, Caldarella C, Muoio B, Bianchi A, Ricci R(2013). A Rare Case of Malignant Granular Cell Tumor of the Colon Incidentally Detected by (18) F-FDG Positron Emission Tomography/Computed Tomography. Nucl Med Mol Imaging vol. 47, (2) 148-150.

Iacovazzo D, Bianchi A, Lugli F, Milardi D, Giampietro A, Lucci-Cordisco E, Doglietto F, Lauriola L et al.(2013). Double pituitary adenomas. Endocrine vol. 43, (2) 452-457.

Iacovazzo D, Lugli F, Giampietro A(2012). Ectopic posterior pituitary causing hyperprolactinemia. Endocrine vol. 42, (2) 449-450.

Iacovazzo D, Lugli F, Bianchi A, Cimino V, Grande G, Perotti G, Treglia G, Rufini V et al. (2012). A Case of ACTH-Secreting Bronchial Carcinoid. NEUROENDOCRINOLOGY. vol. 96, 38-38.

Larghi A, Fusco A, Bianchi A, Lugli F, Iacovazzo D, Celico M, Costamagna G, Pontecorvi A et al. (2012). Endoscopic Ultrasound-Guided Fine Needle Tissue Acquisition (EUS-FNTA) Using a 19-G Needle for Histological Grading of Pancreatic Endocrine Tumors (PETs): A Prospective Study. NEUROENDOCRINOLOGY. vol. 96, 44-44.

Bianchi A, Iacovazzo D, Plastino F, Lugli F, Pontecorvi A, Doglietto GB, Giordano A, Barone CAM et al. (2012). Establishment of a Multidisciplinary Tumor Board for Patients with Neuroendocrine Neoplasms. NEUROENDOCRINOLOGY. vol. 96, 21-21.

Lugli F, Iacovazzo D, Fusco A, Bianchi A, Chiloiro S, Mormando M, Tartaglione L, Piacentini S et al. (2012). Insulin Autoimmune Syndrome Mimicking Insulinoma: A Challenging Diagnosis. NEUROENDOCRINOLOGY. vol. 96, 44-44.

Bianchi A, Iacovazzo D, Fusco A, Lugli F, Giampietro A, Lorusso M, D'Uonnolo A, Perotti G et al. (2011). Medical and Peptide Receptor Radionuclide Therapy (PRRT) with Somatostatin Analogues (SSA) in Well- and Moderately Differentiated Neuroendocrine Tumors. NEUROENDOCRINOLOGY. vol. 94, 16-17.

Iacovazzo D, Lugli F, Fusco A, Bianchi A, Schinzari G, Larghi A, Perotti G, Margaritora S et al. (2011). Pancreatic Metastases from Bronchopulmonary Atypical Carcinoid: An Uncommon Tumor Spreading to a Rare Location. NEUROENDOCRINOLOGY. vol. 94, 27-27.

Fusco A, Bianchi A, Giampietro A, Tilaro L, Cimino V, Veltri F, Piacentini S, D'Uonnolo A et al. (2010). The Clinical Experience at a Single Centre with Pegvisomant Therapy in Acromegaly. ENDOCRINE REVIEWS. vol. 31,

Fusco A, Lugli F, Bianchi A, Iacovazzo D, Larghi A, Tartaglione L, Piacentini S, Perotti G et al. (2010). The Importance of Endoscopic Ultrasound in Detecting Recurrent Gastrinoma in a Case of MEN 1. NEUROENDOCRINOLOGY. vol. 92, 30-31.

Lugli F, Fusco A, Bianchi A, Iacovazzo D, Mormando M, D'Uonnolo A, Rufini V, Doglietto G et al. (2010). The Role of 18F DOPA-PET in a Case of Malignant Pheochromocytoma. NEUROENDOCRINOLOGY. vol. 92, 43-43.

KORBONITS MJ. Germline or somatic GPR101 duplication leads to X-linked acrogigantism: a clinico-pathological and genetic study. Acta Neuropathologica Communications