Publications:  Dr Ioanna Ntalla

Watson HJ, Yilmaz Z, Thornton LM, Hübel C, Coleman JRI, Gaspar HA, Bryois J, Hinney A et al.(2019). Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa. Nat Genet vol. 51, (8) 1207-1214.

Ntalla I, Kanoni S, Zeng L, Giannakopoulou O, Danesh J, Watkins H, Samani NJ, Deloukas P et al.(2019). Genetic Risk Score for Coronary Disease Identifies Predispositions to Cardiovascular and Noncardiovascular Diseases. J Am Coll Cardiol vol. 73, (23) 2932-2942.

Zeng L, Ntalla I, Kessler T, Kastrati A, Erdmann J, UK Biobank CardioMetabolic Consortium CHD Working Group, Danesh J, Watkins H et al.(2019). Genetically modulated educational attainment and coronary disease risk. Eur Heart J

Warrington NM, Beaumont RN, Horikoshi M, Day FR, Helgeland Ø, Laurin C, Bacelis J, Peng S et al.(2019). Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors. Nat Genet vol. 51, (5) 804-814.

Sung YJ, de Las Fuentes L, Winkler TW, Chasman DI, Bentley AR, Kraja AT, Ntalla I, Warren HR et al.(2019). A multi-ancestry genome-wide study incorporating gene-smoking interactions identifies multiple new loci for pulse pressure and mean arterial pressure. Hum Mol Genet

Bentley AR, Sung YJ, Brown MR, Winkler TW, Kraja AT, Ntalla I, Schwander K, Chasman DI et al.(2019). Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids. Nat Genet vol. 51, (4) 636-648.

Justice AE, Karaderi T, Highland HM, Young KL, Graff M, Lu Y, Turcot V, Auer PL et al.(2019). Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution. Nat Genet vol. 51, (3) 452-469.

Ramírez J, Duijvenboden SV, Ntalla I, Mifsud B, Warren HR, Tzanis E, Orini M, Tinker A et al.(2018). Thirty loci identified for heart rate response to exercise and recovery implicate autonomic nervous system. Nat Commun vol. 9, (1)

Mahajan A, Wessel J, Willems SM, Zhao W, Robertson NR, Chu AY, Gan W, Kitajima H et al.(2018). Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes. Nat Genet vol. 50, (4) 559-571.

Nelson CP, Goel A, Butterworth AS, Kanoni S, Webb TR, Marouli E, Zeng L, Ntalla I et al.(2017). Association analyses based on false discovery rate implicate new loci for coronary artery disease. Nat Genet vol. 49, (9) 1385-1391.

Li D, Chang X, Connolly JJ, Tian L, Liu Y, Bhoj EJ, Robinson N, Abrams D et al.(2017). A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling. Sci Rep vol. 7, (1)

Tachmazidou I, Süveges D, Min JL, Ritchie GRS, Steinberg J, Walter K, Iotchkova V, Schwartzentruber J et al.(2017). Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits. Am J Hum Genet vol. 100, (6) 865-884.

Warren HR, Evangelou E, Cabrera CP, Gao H, Ren M, Mifsud B, Ntalla I, Surendran P et al.(2017). Genome-wide association analysis identifies novel blood pressure loci and offers biological insights into cardiovascular risk. Nat Genet vol. 49, (3) 403-415.

Marouli E, Graff M, Medina-Gomez C, Lo KS, Wood AR, Kjaer TR, Fine RS, Lu Y et al.(2017). Rare and low-frequency coding variants alter human adult height. Nature vol. 542, (7640) 186-190.

Iotchkova V, Huang J, Morris JA, Jain D, Barbieri C, Walter K, Min JL, Chen L et al.(2016). Discovery and refinement of genetic loci associated with cardiometabolic risk using dense imputation maps. Nat Genet vol. 48, (11) 1303-1312.

Horikoshi M, Beaumont RN, Day FR, Warrington NM, Kooijman MN, Fernandez-Tajes J, Feenstra B, van Zuydam NR et al.(2016). Genome-wide associations for birth weight and correlations with adult disease. Nature vol. 538, (7624) 248-252.

Jackson VE, Ntalla I, Sayers I, Morris R, Whincup P, Casas J-P, Amuzu A, Choi M et al.(2016). Exome-wide analysis of rare coding variation identifies novel associations with COPD and airflow limitation in MOCS3, IFIT3 and SERPINA12. Thorax vol. 71, (6) 501-509.

Felix JF, Bradfield JP, Monnereau C, van der Valk RJP, Stergiakouli E, Chesi A, Gaillard R, Feenstra B et al.(2016). Genome-wide association analysis identifies three new susceptibility loci for childhood body mass index. Hum Mol Genet vol. 25, (2) 389-403.

Ntalla I, Yannakoulia M, Dedoussis GV(2016). An Overweight Preventive Score associates with obesity and glycemic traits. Metabolism vol. 65, (1) 81-88.

Portelli MA, Bennett ND, Hankinson J, Ntalla I, Henry A, Billington CK, Shaw D, Pogson ZEK et al. (2016). Determining The Contribution Of Il33 And Il1rl1 Polymorphisms To Clinical And Immunological Features Of Asthma. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 193,

Portelli MA, Bennett ND, Ntalla I, Henry A, Billington CK, Shaw D, Pogson ZEK, Fogarty A et al. (2016). Genome Wide Association Study Of Lung Function And Allergy Related Traits In Subjects With Asthma. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 193,

Soler Artigas M, Wain LV, Miller S, Kheirallah AK, Huffman JE, Ntalla I, Shrine N, Obeidat M et al.(2015). Sixteen new lung function signals identified through 1000 Genomes Project reference panel imputation. Nat Commun vol. 6,

Allen RJ, Wain LV, Shrine N, Miller S, Jackson VE, Ntalla I, Artigas MS, Cook JP et al. (2015). Shared polygenic effects of FEV1 in the first genetic study in UK Biobank. GENETIC EPIDEMIOLOGY. vol. 39, 529-530.

Wain LV, Shrine N, Miller S, Jackson VE, Ntalla I, Soler Artigas M, Billington CK, Kheirallah AK et al.(2015). Novel insights into the genetics of smoking behaviour, lung function, and chronic obstructive pulmonary disease (UK BiLEVE): a genetic association study in UK Biobank. Lancet Respir Med vol. 3, (10) 769-781.

Qi Q, Downer MK, Kilpeläinen TO, Taal HR, Barton SJ, Ntalla I, Standl M, Boraska V et al.(2015). Dietary Intake, FTO Genetic Variants, and Adiposity: A Combined Analysis of Over 16,000 Children and Adolescents. Diabetes vol. 64, (7) 2467-2476.

Horikoshi M, Carstensen L, Strachan DP, Kooijman MN, Boh ETH, Joshi PK, Van Leeuwen EM, Bradfield JP et al. (2015). Large Scale Genome-Wide Association Study for Birth Weight Finds Eight Novel Loci Extending the Genetic Link between Early Growth and Type 2 Diabetes. DIABETES. vol. 64, A6-A7.

van der Valk RJP, Kreiner-Møller E, Kooijman MN, Guxens M, Stergiakouli E, Sääf A, Bradfield JP, Geller F et al.(2015). A novel common variant in DCST2 is associated with length in early life and height in adulthood. Hum Mol Genet vol. 24, (4) 1155-1168.

Wessel J, Chu AY, Willems SM, Wang S, Yaghootkar H, Brody JA, Dauriz M, Hivert M-F et al.(2015). Low-frequency and rare exome chip variants associate with fasting glucose and type 2 diabetes susceptibility. Nat Commun vol. 6,

Miller S, Wain L, Shrine N, Ntalla I, Cook J, Sayers I, Morris A, Zeggini E et al. (2015). The Uk Bileve Study: The First Genetic Study In Uk Biobank Identifies Novel Regions Associated With Airway Obstruction And Smoking Behaviour. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE. vol. 191,

Lazopoulou N, Gkioka E, Ntalla I, Pervanidou P, Magiakou A-M, Roma-Giannikou E, Chrousos GP, Papassotiriou I et al.(2015). The combined effect of MC4R and FTO risk alleles on childhood obesity in Greece. Hormones (Athens) vol. 14, (1) 126-133.

Panoutsopoulou K, Hatzikotoulas K, Xifara DK, Colonna V, Farmaki A-E, Ritchie GRS, Southam L, Gilly A et al.(2014). Genetic characterization of Greek population isolates reveals strong genetic drift at missense and trait-associated variants. Nat Commun vol. 5,

Boraska V, Franklin CS, Floyd JAB, Thornton LM, Huckins LM, Southam L, Rayner NW, Tachmazidou I et al.(2014). A genome-wide association study of anorexia nervosa. Mol Psychiatry vol. 19, (10) 1085-1094.

Cousminer DL, Stergiakouli E, Berry DJ, Ang W, Groen-Blokhuis MM, Körner A, Siitonen N, Ntalla I et al.(2014). Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty. Hum Mol Genet vol. 23, (16) 4452-4464.

Qi Q, Taa HR, Barton S, Dedoussis G, Standl M, Huikari V, Jong JK-D, Koerner A et al. (2014). FTO Genetic Variants, Dietary Intakes, and Adiposity: Results from Over 16,000 Children and Adolescents. DIABETES. vol. 63, A100-A100.

Ntalla I, Giannakopoulou M, Vlachou P, Giannitsopoulou K, Gkesou V, Makridi C, Marougka M, Mikou G et al.(2014). Body composition and eating behaviours in relation to dieting involvement in a sample of urban Greek adolescents from the TEENAGE (TEENs of Attica: Genes & Environment) study. Public Health Nutr vol. 17, (3) 561-568.

Ntalla I, Panoutsopoulou K, Vlachou P, Southam L, William Rayner N, Zeggini E, Dedoussis GV(2013). Replication of established common genetic variants for adult BMI and childhood obesity in Greek adolescents: the TEENAGE study. Ann Hum Genet vol. 77, (3) 268-274.

Hruby A, Ngwa JS, Renström F, Wojczynski MK, Ganna A, Hallmans G, Houston DK, Jacques PF et al.(2013). Higher magnesium intake is associated with lower fasting glucose and insulin, with no evidence of interaction with select genetic loci, in a meta-analysis of 15 CHARGE Consortium Studies. J Nutr vol. 143, (3) 345-353.

Nettleton JA, Hivert M-F, Lemaitre RN, McKeown NM, Mozaffarian D, Tanaka T, Wojczynski MK, Hruby A et al.(2013). Meta-analysis investigating associations between healthy diet and fasting glucose and insulin levels and modification by loci associated with glucose homeostasis in data from 15 cohorts. Am J Epidemiol vol. 177, (2) 103-115.

Horikoshi M, Yaghootkar H, Mook-Kanamori DO, Sovio U, Taal HR, Hennig BJ, Bradfield JP, St Pourcain B et al.(2013). New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism. Nat Genet vol. 45, (1) 76-82.

Boraska V, Davis OSP, Cherkas LF, Helder SG, Harris J, Krug I, Liao TP-C, Treasure J et al.(2012). Genome-wide association analysis of eating disorder-related symptoms, behaviors, and personality traits. Am J Med Genet B Neuropsychiatr Genet vol. 159B, (7) 803-811.

Taal HR, Pourcain BS, Thiering E, Das S, Mook-Kanamori DO, Warrington NM, Kaakinen M, Kreiner-Møller E et al.(2012). Common variants at 12q15 and 12q24 are associated with infant head circumference. Nat Genet vol. 44, (5) 532-538.

Ikram MA, Fornage M, Smith AV, Seshadri S, Schmidt R, Debette S, Vrooman HA, Sigurdsson S et al.(2012). Common variants at 6q22 and 17q21 are associated with intracranial volume. Nat Genet vol. 44, (5) 539-544.

Papoutsakis C, Yannakoulia M, Ntalla I, Dedoussis GV(2012). Metabolic syndrome in a Mediterranean pediatric cohort: prevalence using International Diabetes Federation-derived criteria and associations with adiponectin and leptin. Metabolism vol. 61, (2) 140-145.

Boraska V, Day-Williams A, Franklin CS, Elliott KS, Panoutsopoulou K, Tachmazidou I, Albrecht E, Bandinelli S et al.(2012). Genome-wide association study to identify common variants associated with brachial circumference: a meta-analysis of 14 cohorts. PLoS One vol. 7, (3)

Barker A, Sharp SJ, Timpson NJ, Bouatia-Naji N, Warrington NM, Kanoni S, Beilin LJ, Brage S et al.(2011). Association of genetic Loci with glucose levels in childhood and adolescence: a meta-analysis of over 6,000 children. Diabetes vol. 60, (6) 1805-1812.

Yannakoulia M, Ntalla I, Papoutsakis C, Farmaki A-E, Dedoussis GV(2010). Consumption of vegetables, cooked meals, and eating dinner is negatively associated with overweight status in children. J Pediatr vol. 157, (5) 815-820.

Ntalla I, Dedoussis G, Yannakoulia M, Smart MC, Louizou E, Sakka SD, Papoutsakis C, Talmud PJ(2009). ADIPOQ gene polymorphism rs1501299 interacts with fibre intake to affect adiponectin concentration in children: the GENe-Diet Attica Investigation on childhood obesity. Eur J Nutr vol. 48, (8) 493-497.

Ntalla I, Smart M, Louizou E, Yiannakoulia M, Papoutsakis K, Talmud P, Dedoussis G (2008). ADIPOQ gene SNP associations with circulating adiponectin, markers of obesity, insulin resistance, and other components of the metabolic syndrome in school-aged children from the GENDAI study. FEBS JOURNAL. vol. 275, 315-315.

Ntalla I, Dedoussis G, Yannakoulia M, Smart M, Louizou E, Papoutsakis C, Talmud P(2008). Dietary Fiber x+276G/T ADIPOQ Gene SNP Interaction Affects Adiponectin Concentration in Children: The Gene and Diet Attica Investigation (GENDAI). JOURNAL OF NUTRIGENETICS AND NUTRIGENOMICS vol. 1, (6) 292-292.

Chiou A, Salta FN, Kalogeropoulos N, Mylona A, Ntalla I, Andrikopoulos NK(2007). Retention and distribution of polyphenols after pan-frying of French fries in oils enriched with olive leaf extract. J Food Sci vol. 72, (8) S574-S584.