Publications: Dr James Griffin

Walker PGT, Cairns M, Slater H, Gutman J, Kayentao K, Williams JE, Coulibaly SO, Khairallah C et al. ( 2020 ) . Modelling the incremental benefit of introducing malaria screening strategies to antenatal care in Africa . Nature Communications vol. 11 , ( 1 )

Verity R, Okell LC, Dorigatti I, Winskill P, Whittaker C, Imai N, Cuomo-Dannenburg G, Thompson H et al. ( 2020 ) . Estimates of the severity of coronavirus disease 2019: a model-based analysis . The Lancet Infectious Diseases

Bretscher MT, Dahal P, Griffin J, Stepniewska K, Bassat Q, Baudin E, D'alessandro U, Djimde AA et al. ( 2020 ) . The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of pfmdr1 86Y and pfcrt 76T: A meta-analysis of individual patient data . BMC Medicine vol. 18 , ( 1 )

Sherrard-Smith E, Skarp JE, Beale AD, Fornadel C, Norris LC, Moore SJ, Mihreteab S, Charlwood JD et al. ( 2019 ) . Mosquito feeding behavior and how it influences residual malaria transmission across Africa . Proceedings of the National Academy of Sciences of the United States of America vol. 116 , ( 30 ) 15086 - 15096 .

Sherrard-Smith E, Griffin JT, Winskill P, Corbel V, Pennetier C, Djénontin A, Moore S, Richardson JH et al. ( 2018 ) . Systematic review of indoor residual spray efficacy and effectiveness against Plasmodium falciparum in Africa . Nature Communications vol. 9 , ( 1 )

Hogan AB, Winskill P, Verity R, Griffin JT, Ghani AC ( 2018 ) . Modelling population-level impact to inform target product profiles for childhood malaria vaccines . BMC Medicine vol. 16 , ( 1 )

Watson OJ, Routledge I, Griffin JT, Ghani AC ( 2018 ) . Predictive Malaria Epidemiology, Models of Malaria Control Interventions and Elimination . Encyclopedia of Malaria ,

Routledge I, Watson OJ, Griffin JT, Ghani AC ( 2018 ) . Predictive Malaria Epidemiology, Models of Malaria Transmission and Elimination . Encyclopedia of Malaria ,

Winskill P, Slater HC, Griffin JT, Ghani AC, Walker PGT ( 2017 ) . The US President's Malaria Initiative, Plasmodium falciparum transmission and mortality: A modelling study . PLoS Medicine vol. 14 , ( 11 )

Bretscher MT, Griffin JT, Ghani AC, Okell LC ( 2017 ) . Modelling the benefits of long-acting or transmission-blocking drugs for reducing Plasmodium falciparum transmission by case management or by mass treatment . Malaria Journal vol. 16 , Article 1 , 341 - 341 .

Okell LC, Griffin JT, Roper C ( 2017 ) . Mapping sulphadoxine-pyrimethamine-resistant Plasmodium falciparum malaria in infected humans and in parasite populations in Africa . Scientific Reports vol. 7 ,

Patouillard E, Griffin J, Bhatt S, Ghani A, Cibulskis R ( 2017 ) . Global investment targets for malaria control and elimination between 2016 and 2030 . BMJ Global Health vol. 2 , Article 2 ,

Winskill P, Walker PGT, Griffin JT, Ghani AC ( 2017 ) . Modelling the cost-effectiveness of introducing the RTS,S malaria vaccine relative to scaling up other malaria interventions in sub-Saharan Africa . BMJ Global Health vol. 2 , ( 1 ) e000090 - e000090 .

Churcher TS, Sinden RE, Edwards NJ, Poulton ID, Rampling TW, Brock PM, Griffin JT, Upton LM et al. ( 2017 ) . Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts . PLOS Pathogens vol. 13 , ( 1 ) e1006108 - e1006108 .

Churcher TS, Lissenden N, Griffin JT, Worrall E, Ranson H ( 2016 ) . The impact of pyrethroid resistance on the efficacy and effectiveness of bednets for malaria control in Africa . eLife vol. 5 , Article e16090 ,

Griffin JT ( 2016 ) . Is a reproduction number of one a threshold for Plasmodium falciparum malaria elimination? . Malaria Journal vol. 15 , ( 1 ) 389 - 389 .

Walker PG, Griffin JT, Ferguson NM, Ghani AC ( 2016 ) . Estimating the most efficient allocation of interventions to achieve reductions in Plasmodium falciparum malaria burden and transmission in Africa: a modelling study . The Lancet Global Health vol. 4 , ( 7 ) e474 - e484 .

Marshall JM, Touré M, Ouédraogo AL, Ndhlovu M, Kiware SS, Rezai A, Nkhama E, Griffin JT et al. ( 2016 ) . Key traveller groups of relevance to spatial malaria transmission: a survey of movement patterns in four sub-Saharan African countries . Malaria Journal vol. 15 , 200 - 200 .

Penny MA, Verity R, Bever CA, Sauboin C, Galactionova K, Flasche S, White MT, Wenger EA et al. ( 2016 ) . Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: A systematic comparison of predictions from four mathematical models . The Lancet vol. 387 , ( 10016 ) 367 - 375 .

Griffin JT, Bhatt S, Sinka ME, Gething PW, Lynch M, Patouillard E, Shutes E, Newman RD et al. ( 2016 ) . Potential for reduction of burden and local elimination of malaria by reducing Plasmodium falciparum malaria transmission: a mathematical modelling study . Lancet Infectious Diseases vol. 16 , ( 4 ) 465 - 472 .

Slater HC, Griffin JT, Ghani AC, Okell LC ( 2016 ) . Assessing the potential impact of artemisinin and partner drug resistance in sub-Saharan Africa . Malaria Journal vol. 15 , ( 1 )

White MT, Verity R, Griffin JT, Asante KP, Owusu-Agyei S, Greenwood B, Drakeley C, Gesase S et al. ( 2015 ) . Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: Secondary analysis of data from a phase 3 randomised controlled trial . The Lancet Infectious Diseases vol. 15 , ( 12 ) 1450 - 1458 .

Van Den Hoogen LL, Griffin JT, Cook J, Sepúlveda N, Corran P, Conway DJ, Milligan P, Affara M et al. ( 2015 ) . Serology describes a profile of declining malaria transmission in Farafenni, the Gambia . Malaria Journal vol. 14 , ( 1 )

Bhatt S, Weiss DJ, Cameron E, Bisanzio D, Mappin B, Dalrymple U, Battle KE, Moyes CL et al. ( 2015 ) . The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015 . Nature vol. 526 , ( 7572 ) 207 - 211 .

Cameron E, Battle KE, Bhatt S, Weiss DJ, Bisanzio D, Mappin B, Dalrymple U, Hay SI et al. ( 2015 ) . Defining the relationship between infection prevalence and clinical incidence of Plasmodium falciparum malaria . Nature Communications vol. 6 ,

Cairns ME, Walker PGT, Okell LC, Griffin JT, Garske T, Asante KP, Owusu-Agyei S, Diallo D et al. ( 2015 ) . Seasonality in malaria transmission: Implications for case-management with long-acting artemisinin combination therapy in sub-Saharan Africa . Malaria Journal vol. 14 , ( 1 )

Walker PGT, White MT, Griffin JT, Reynolds A, Ferguson NM, Ghani AC ( 2015 ) . Malaria morbidity and mortality in Ebola-affected countries caused by decreased health-care capacity, and the potential effect of mitigation strategies: A modelling analysis . The Lancet Infectious Diseases vol. 15 , ( 7 ) 825 - 832 .

Griffin JT, Hollingsworth TD, Reyburn H, Drakeley CJ, Riley EM, Ghani AC ( 2015 ) . Gradual acquisition of immunity to severe malaria with increasing exposure . Proceedings. Biological sciences / The Royal Society vol. 282 , ( 1801 )

Griffin JT ( 2015 ) . The interaction between seasonality and pulsed interventions against malaria in their effects on the reproduction number . PLoS Comput Biol vol. 11 , ( 1 ) e1004057 - e1004057 .

White MT, Griffin JT, Akpogheneta O, Conway DJ, Koram KA, Riley EM, Ghani AC ( 2014 ) . Dynamics of the antibody response to Plasmodium falciparum infection in African children . Journal of Infectious Diseases vol. 210 , ( 7 ) 1115 - 1122 .

Bretscher MT, Griffin JT, Hugo P, Baker M, Ghani A, Okell L, The AS-AQ Post-Treatment Prophylaxis Study Group ( 2014 ) . A comparison of the duration of post-treatment protection of artemether-lumefantrine, dihydroartemisinin-piperaquine and artesunate-amodiaquine for the treatment of uncomplicated malaria . Malaria Journal vol. 13 , ( Suppl 1 )

Pinsent A, Read JM, Griffin JT, Smith V, Gething PW, Ghani AC, Pasvol G, Hollingsworth TD ( 2014 ) . Risk factors for UK Plasmodium falciparum cases . Malaria Journal vol. 13 , ( 1 )

White MT, Bejon P, Olotu A, Griffin JT, Bojang K, Lusingu J, Salim N, Abdulla S et al. ( 2014 ) . A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine . BMC Medicine vol. 12 , ( 1 )

Griffin JT, Ferguson NM, Ghani AC ( 2014 ) . Estimates of the changing age-burden of Plasmodium falciparum malaria disease in sub-Saharan Africa . Nature Communications vol. 5 ,

Okell LC, Cairns M, Griffin JT, Ferguson NM, Tarning J, Jagoe G, Hugo P, Baker M et al. ( 2014 ) . Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis . Nature Communications vol. 5 ,

White MT, Griffin JT, Ghani AC ( 2013 ) . The design and statistical power of treatment re-infection studies of the association between pre-erythrocytic immunity and infection with Plasmodium falciparum . Malaria Journal vol. 12 , ( 1 )

White MT, Bejon P, Olotu A, Griffin JT, Riley EM, Kester KE, Ockenhouse CF, Ghani AC ( 2013 ) . The Relationship between RTS,S Vaccine-Induced Antibodies, CD4⁺ T Cell Responses and Protection against Plasmodium falciparum Infection . PLoS ONE vol. 8 , ( 4 )

Walker PGT, Griffin JT, Cairns M, Rogerson SJ, Van Eijk AM, Ter Kuile F, Ghani AC ( 2013 ) . A model of parity-dependent immunity to placental malaria . Nature Communications vol. 4 ,

Bousema T, Stevenson J, Baidjoe A, Stresman G, Griffin JT, Kleinschmidt I, Remarque EJ, Vulule J et al. ( 2013 ) . The impact of hotspot-targeted interventions on malaria transmission: Study protocol for a cluster-randomized controlled trial . Trials vol. 14 , ( 1 )

Okell LC, Bousema T, Griffin JT, Ouédraogo AL, Ghani AC, Drakeley CJ ( 2012 ) . Factors determining the occurrence of submicroscopic malaria infections and their relevance for control . Nature Communications vol. 3 ,

Bousema T, Griffin JT, Sauerwein RW, Smith DL, Churcher TS, Takken W, Ghani A, Drakeley C et al. ( 2012 ) . Hitting hotspots: Spatial targeting of malaria for control and elimination . PLoS Medicine vol. 9 , ( 1 )

Opatowski L, Fraser C, Griffin J, de Silva E, van Kerkhove MD, Lyons EJ, Cauchemez S, Ferguson NM ( 2011 ) . Transmission characteristics of the 2009 h1n1 influenza pandemic: Comparison of 8 southern hemisphere countries . PLoS Pathogens vol. 7 , ( 9 )

White MT, Griffin JT, Churcher TS, Ferguson NM, Basáñez MG, Ghani AC ( 2011 ) . Modelling the impact of vector control interventions on Anopheles gambiae population dynamics . Parasites and Vectors vol. 4 , ( 1 )

Okell LC, Griffin JT, Kleinschmidt I, Hollingsworth TD, Churcher TS, White MJ, Bousema T, Drakeley CJ et al. ( 2011 ) . The potential contribution of mass treatment to the control of plasmodium falciparum malaria . PLoS ONE vol. 6 , ( 5 )

Griffin JT, Garske T, Ghani AC, Clarke PS ( 2011 ) . Joint estimation of the basic reproduction number and generation time parameters for infectious disease outbreaks . Biostatistics vol. 12 , ( 2 ) 303 - 312 .

White MT, Griffin JT, Riley EM, Drakeley CJ, Moorman AM, Sumba PO, Kazura JW, Ghani AC et al. ( 2011 ) . Efficacy model for antibody-mediated pre-erythrocytic malaria vaccines . Proceedings of the Royal Society B: Biological Sciences vol. 278 , ( 1710 ) 1298 - 1305 .

Griffin JT, Cairns M, Ghani AC, Roper C, Schellenberg D, Carneiro I, Newman RD, Grobusch MP et al. ( 2010 ) . Protective efficacy of intermittent preventive treatment of malaria in infants (IPTi) using sulfadoxine- pyrimethamine and parasite resistance . PLoS ONE vol. 5 , ( 9 ) 1 - 11 .

Griffin JT, Hollingsworth TD, Okell LC, Churcher TS, White M, Hinsley W, Bousema T, Drakeley CJ et al. ( 2010 ) . Reducing Plasmodium falciparum malaria transmission in Africa: A model-based evaluation of intervention strategies . PLoS Medicine vol. 7 , ( 8 )

Carneiro I, Roca-Feltrer A, Griffin JT, Smith L, Tanner M, Schellenberg JA, Greenwood B, Schellenberg D ( 2010 ) . Age-patterns of malaria vary with severity, transmission intensity and seasonality in sub-Saharan Africa: A systematic review and pooled analysis . PLoS ONE vol. 5 , ( 2 )

White MT, Griffin JT, Drakeley CJ, Ghani AC ( 2010 ) . Heterogeneity in malaria exposure and vaccine response: implications for the interpretation of vaccine efficacy trials . Malaria journal vol. 9 ,

Bousema T, Okell L, Shekalaghe S, Griffin JT, Omar S, Sawa P, Sutherland C, Sauerwein R et al. ( 2010 ) . Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs . Malaria journal vol. 9 ,

Ghani A, Baguelin M, Griffin J, Flasche S, van Hoek AJ, Cauchemez S, Donnelly C, Robertson C et al. ( 2009 ) . The Early Transmission Dynamics of H1N1pdm Influenza in the United Kingdom . PLoS Curr vol. 1 ,

Stewart L, Gosling R, Griffin J, Gesase S, Campo J, Hashim R, Masika P, Mosha J et al. ( 2009 ) . Rapid assessment of malaria transmission using age-specific sero-conversion rates . PLoS ONE vol. 4 , ( 6 )

Fraser C, Donnelly CA, Cauchemez S, Hanage WP, Van Kerkhove MD, Hollingsworth TD, Griffin J, Baggaley RF et al. ( 2009 ) . Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings . Science vol. 324 , ( 5934 ) 1557 - 1561 .

Baggaley RF, Griffin JT, Chapman R, Hollingsworth TD, Nagot N, Delany S, Mayaud P, De Wolf F et al. ( 2009 ) . Estimating the public health impact of the effect of herpes simplex virus suppressive therapy on plasma HIV-1 viral load . AIDS vol. 23 , ( 8 ) 1005 - 1013 .

Ghani AC, Sutherland CJ, Riley EM, Drakeley CJ, Griffin JT, Gosling RD, Filipe JAN ( 2009 ) . Loss of population levels of immunity to malaria as a result of exposure-reducing interventions: Consequences for interpretation of disease trends . PLoS ONE vol. 4 , ( 2 )

Corran PH, Cook J, Lynch C, Leendertse H, Manjurano A, Griffin J, Cox J, Abeku T et al. ( 2008 ) . Dried blood spots as a source of anti-malarial antibodies for epidemiological studies . Malaria Journal vol. 7 ,

Gras L, Kesselring AM, Griffin JT, Van Sighem AI, Fraser C, Ghani AC, Miedema F, Reiss P et al. ( 2007 ) . CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater . Journal of Acquired Immune Deficiency Syndromes vol. 45 , ( 2 ) 183 - 192 .

Griffin JT, Fraser C, Gras L, De Wolf F, Ghani AC ( 2006 ) . The effect on treatment comparisons of different measurement frequencies in human immunodeficiency virus observational databases . American Journal of Epidemiology vol. 163 , ( 7 ) 676 - 683 .

Fidler S, Fraser C, Fox J, Tamm N, Griffin JT, Weber J ( 2006 ) . Comparative potency of three antiretroviral therapy regimes in primary HIV infection . AIDS vol. 20 , ( 2 ) 247 - 252 .

Ghani AC, Donnelly CA, Cox DR, Griffin JT, Fraser C, Lam TH, Ho LM, Chan WS et al. ( 2005 ) . Methods for estimating the case fatality ratio for a novel, emerging infectious disease . American Journal of Epidemiology vol. 162 , ( 5 ) 479 - 486 .

Griffin J ( 2005 ) . Handbook of Statistics, Volume 23, Advances in Survival Analysis . Journal of the Royal Statistical Society Series A (Statistics in Society) vol. 168 , ( 3 ) 630 - 630 .