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Publications:  Dr James Griffin

Verity R, Okell LC, Dorigatti I, Winskill P, Whittaker C, Imai N, Cuomo-Dannenburg G, Thompson H et al.(2020). Estimates of the severity of coronavirus disease 2019: a model-based analysis. The Lancet Infectious Diseases
Bretscher MT, Dahal P, Griffin J, Stepniewska K, Bassat Q, Baudin E, D'alessandro U, Djimde AA et al.(2020). The duration of chemoprophylaxis against malaria after treatment with artesunate-amodiaquine and artemether-lumefantrine and the effects of pfmdr1 86Y and pfcrt 76T: A meta-analysis of individual patient data. BMC Medicine vol. 18, (1)
Sherrard-Smith E, Skarp JE, Beale AD, Fornadel C, Norris LC, Moore SJ, Mihreteab S, Charlwood JD et al.(2019). Mosquito feeding behavior and how it influences residual malaria transmission across Africa. Proceedings of the National Academy of Sciences of the United States of America vol. 116, (30) 15086-15096.
Sherrard-Smith E, Griffin JT, Winskill P, Corbel V, Pennetier C, Djénontin A, Moore S, Richardson JH et al.(2018). Systematic review of indoor residual spray efficacy and effectiveness against Plasmodium falciparum in Africa. Nature Communications vol. 9, (1)
Hogan AB, Winskill P, Verity R, Griffin JT, Ghani AC(2018). Modelling population-level impact to inform target product profiles for childhood malaria vaccines. BMC Medicine vol. 16, (1)
Winskill P, Slater HC, Griffin JT, Ghani AC, Walker PGT(2017). The US President's Malaria Initiative, Plasmodium falciparum transmission and mortality: A modelling study. PLoS Medicine vol. 14, (11)
Bretscher MT, Griffin JT, Ghani AC, Okell LC(2017). Modelling the benefits of long-acting or transmission-blocking drugs for reducing Plasmodium falciparum transmission by case management or by mass treatment. Malaria Journal vol. 16, Article 1, 341-341.
Okell LC, Griffin JT, Roper C(2017). Mapping sulphadoxine-pyrimethamine-resistant Plasmodium falciparum malaria in infected humans and in parasite populations in Africa. Scientific Reports vol. 7,
Patouillard E, Griffin J, Bhatt S, Ghani A, Cibulskis R(2017). Global investment targets for malaria control and elimination between 2016 and 2030. BMJ Global Health vol. 2, Article 2,
Winskill P, Walker PGT, Griffin JT, Ghani AC(2017). Modelling the cost-effectiveness of introducing the RTS,S malaria vaccine relative to scaling up other malaria interventions in sub-Saharan Africa. BMJ Global Health vol. 2, (1) e000090-e000090.
Churcher TS, Sinden RE, Edwards NJ, Poulton ID, Rampling TW, Brock PM, Griffin JT, Upton LM et al.(2017). Probability of Transmission of Malaria from Mosquito to Human Is Regulated by Mosquito Parasite Density in Naïve and Vaccinated Hosts. PLOS Pathogens vol. 13, (1) e1006108-e1006108.
Churcher TS, Lissenden N, Griffin JT, Worrall E, Ranson H(2016). The impact of pyrethroid resistance on the efficacy and effectiveness of bednets for malaria control in Africa. eLife vol. 5, Article e16090,
Griffin JT(2016). Is a reproduction number of one a threshold for Plasmodium falciparum malaria elimination?. Malaria Journal vol. 15, (1) 389-389.
Walker PG, Griffin JT, Ferguson NM, Ghani AC(2016). Estimating the most efficient allocation of interventions to achieve reductions in Plasmodium falciparum malaria burden and transmission in Africa: a modelling study. Lancet Glob Health vol. 4, (7) e474-e484.
Marshall JM, Touré M, Ouédraogo AL, Ndhlovu M, Kiware SS, Rezai A, Nkhama E, Griffin JT et al.(2016). Key traveller groups of relevance to spatial malaria transmission: a survey of movement patterns in four sub-Saharan African countries. Malaria Journal vol. 15, 200-200.
Penny MA, Verity R, Bever CA, Sauboin C, Galactionova K, Flasche S, White MT, Wenger EA et al.(2016). Public health impact and cost-effectiveness of the RTS,S/AS01 malaria vaccine: A systematic comparison of predictions from four mathematical models. The Lancet vol. 387, (10016) 367-375.
Griffin JT, Bhatt S, Sinka ME, Gething PW, Lynch M, Patouillard E, Shutes E, Newman RD et al.(2016). Potential for reduction of burden and local elimination of malaria by reducing Plasmodium falciparum malaria transmission: a mathematical modelling study. Lancet Infectious Diseases vol. 16, (4) 465-472.
Slater HC, Griffin JT, Ghani AC, Okell LC(2016). Assessing the potential impact of artemisinin and partner drug resistance in sub-Saharan Africa. Malaria Journal vol. 15, (1)
White MT, Verity R, Griffin JT, Asante KP, Owusu-Agyei S, Greenwood B, Drakeley C, Gesase S et al.(2015). Immunogenicity of the RTS,S/AS01 malaria vaccine and implications for duration of vaccine efficacy: Secondary analysis of data from a phase 3 randomised controlled trial. The Lancet Infectious Diseases vol. 15, (12) 1450-1458.
Van Den Hoogen LL, Griffin JT, Cook J, Sepúlveda N, Corran P, Conway DJ, Milligan P, Affara M et al.(2015). Serology describes a profile of declining malaria transmission in Farafenni, the Gambia. Malaria Journal vol. 14, (1)
Bhatt S, Weiss DJ, Cameron E, Bisanzio D, Mappin B, Dalrymple U, Battle KE, Moyes CL et al.(2015). The effect of malaria control on Plasmodium falciparum in Africa between 2000 and 2015. Nature vol. 526, (7572) 207-211.
Cameron E, Battle KE, Bhatt S, Weiss DJ, Bisanzio D, Mappin B, Dalrymple U, Hay SI et al.(2015). Defining the relationship between infection prevalence and clinical incidence of Plasmodium falciparum malaria. Nature Communications vol. 6,
Cairns ME, Walker PGT, Okell LC, Griffin JT, Garske T, Asante KP, Owusu-Agyei S, Diallo D et al.(2015). Seasonality in malaria transmission: Implications for case-management with long-acting artemisinin combination therapy in sub-Saharan Africa. Malaria Journal vol. 14, (1)
Griffin JT, Hollingsworth TD, Reyburn H, Drakeley CJ, Riley EM, Ghani AC(2015). Gradual acquisition of immunity to severe malaria with increasing exposure. Proceedings. Biological sciences / The Royal Society vol. 282, (1801)
Griffin JT(2015). The interaction between seasonality and pulsed interventions against malaria in their effects on the reproduction number. PLoS Comput Biol vol. 11, (1) e1004057-e1004057.
Walker PGT, White MT, Griffin JT, Reynolds A, Ferguson NM, Ghani AC(2015). Malaria morbidity and mortality in Ebola-affected countries caused by decreased health-care capacity, and the potential effect of mitigation strategies: A modelling analysis. The Lancet Infectious Diseases vol. 15, (7) 825-832.
Pinsent A, Read JM, Griffin JT, Smith V, Gething PW, Ghani AC, Pasvol G, Hollingsworth TD(2014). Risk factors for UK Plasmodium falciparum cases. Malaria Journal vol. 13, (1)
White MT, Bejon P, Olotu A, Griffin JT, Bojang K, Lusingu J, Salim N, Abdulla S et al.(2014). A combined analysis of immunogenicity, antibody kinetics and vaccine efficacy from phase 2 trials of the RTS,S malaria vaccine. BMC Medicine vol. 12, (1)
Griffin JT, Ferguson NM, Ghani AC(2014). Estimates of the changing age-burden of Plasmodium falciparum malaria disease in sub-Saharan Africa. Nature Communications vol. 5,
Okell LC, Cairns M, Griffin JT, Ferguson NM, Tarning J, Jagoe G, Hugo P, Baker M et al.(2014). Contrasting benefits of different artemisinin combination therapies as first-line malaria treatments using model-based cost-effectiveness analysis. Nature Communications vol. 5,
White MT, Griffin JT, Akpogheneta O, Conway DJ, Koram KA, Riley EM, Ghani AC(2014). Dynamics of the antibody response to Plasmodium falciparum infection in African children. Journal of Infectious Diseases vol. 210, (7) 1115-1122.
White MT, Griffin JT, Ghani AC(2013). The design and statistical power of treatment re-infection studies of the association between pre-erythrocytic immunity and infection with Plasmodium falciparum. Malaria Journal vol. 12, (1)
White MT, Bejon P, Olotu A, Griffin JT, Riley EM, Kester KE, Ockenhouse CF, Ghani AC(2013). The Relationship between RTS,S Vaccine-Induced Antibodies, CD4<sup>+</sup> T Cell Responses and Protection against Plasmodium falciparum Infection. PLoS ONE vol. 8, (4)
Walker PGT, Griffin JT, Cairns M, Rogerson SJ, Van Eijk AM, Ter Kuile F, Ghani AC(2013). A model of parity-dependent immunity to placental malaria. Nature Communications vol. 4,
Bousema T, Stevenson J, Baidjoe A, Stresman G, Griffin JT, Kleinschmidt I, Remarque EJ, Vulule J et al.(2013). The impact of hotspot-targeted interventions on malaria transmission: Study protocol for a cluster-randomized controlled trial. Trials vol. 14, (1)
Okell LC, Bousema T, Griffin JT, Ouédraogo AL, Ghani AC, Drakeley CJ(2012). Factors determining the occurrence of submicroscopic malaria infections and their relevance for control. Nature Communications vol. 3,
Bousema T, Griffin JT, Sauerwein RW, Smith DL, Churcher TS, Takken W, Ghani A, Drakeley C et al.(2012). Hitting hotspots: Spatial targeting of malaria for control and elimination. PLoS Medicine vol. 9, (1)
Opatowski L, Fraser C, Griffin J, de Silva E, van Kerkhove MD, Lyons EJ, Cauchemez S, Ferguson NM(2011). Transmission characteristics of the 2009 h1n1 influenza pandemic: Comparison of 8 southern hemisphere countries. PLoS Pathogens vol. 7, (9)
White MT, Griffin JT, Churcher TS, Ferguson NM, Basáñez MG, Ghani AC(2011). Modelling the impact of vector control interventions on Anopheles gambiae population dynamics. Parasites and Vectors vol. 4, (1)
Okell LC, Griffin JT, Kleinschmidt I, Hollingsworth TD, Churcher TS, White MJ, Bousema T, Drakeley CJ et al.(2011). The potential contribution of mass treatment to the control of plasmodium falciparum malaria. PLoS ONE vol. 6, (5)
Griffin JT, Garske T, Ghani AC, Clarke PS(2011). Joint estimation of the basic reproduction number and generation time parameters for infectious disease outbreaks. Biostatistics vol. 12, (2) 303-312.
White MT, Griffin JT, Riley EM, Drakeley CJ, Moorman AM, Sumba PO, Kazura JW, Ghani AC et al.(2011). Efficacy model for antibody-mediated pre-erythrocytic malaria vaccines. Proceedings of the Royal Society B: Biological Sciences vol. 278, (1710) 1298-1305.
Griffin JT, Cairns M, Ghani AC, Roper C, Schellenberg D, Carneiro I, Newman RD, Grobusch MP et al.(2010). Protective efficacy of intermittent preventive treatment of malaria in infants (IPTi) using sulfadoxine- pyrimethamine and parasite resistance. PLoS ONE vol. 5, (9) 1-11.
Griffin JT, Hollingsworth TD, Okell LC, Churcher TS, White M, Hinsley W, Bousema T, Drakeley CJ et al.(2010). Reducing Plasmodium falciparum malaria transmission in Africa: A model-based evaluation of intervention strategies. PLoS Medicine vol. 7, (8)
Ghani A, Baguelin M, Griffin J, Flasche S, van Hoek AJ, Cauchemez S, Donnelly C, Robertson C et al.(2010). The Early Transmission Dynamics of H1N1pdm Influenza in the United Kingdom. PLoS Currents vol. 1, RRN1130-RRN1130.
Carneiro I, Roca-Feltrer A, Griffin JT, Smith L, Tanner M, Schellenberg JA, Greenwood B, Schellenberg D(2010). Age-patterns of malaria vary with severity, transmission intensity and seasonality in sub-Saharan Africa: A systematic review and pooled analysis. PLoS ONE vol. 5, (2)
White MT, Griffin JT, Drakeley CJ, Ghani AC(2010). Heterogeneity in malaria exposure and vaccine response: implications for the interpretation of vaccine efficacy trials. Malaria journal vol. 9,
Bousema T, Okell L, Shekalaghe S, Griffin JT, Omar S, Sawa P, Sutherland C, Sauerwein R et al.(2010). Revisiting the circulation time of Plasmodium falciparum gametocytes: molecular detection methods to estimate the duration of gametocyte carriage and the effect of gametocytocidal drugs. Malaria journal vol. 9,
Stewart L, Gosling R, Griffin J, Gesase S, Campo J, Hashim R, Masika P, Mosha J et al.(2009). Rapid assessment of malaria transmission using age-specific sero-conversion rates. PLoS ONE vol. 4, (6)
Baggaley RF, Griffin JT, Chapman R, Hollingsworth TD, Nagot N, Delany S, Mayaud P, De Wolf F et al.(2009). Estimating the public health impact of the effect of herpes simplex virus suppressive therapy on plasma HIV-1 viral load. AIDS vol. 23, (8) 1005-1013.
Fraser C, Donnelly CA, Cauchemez S, Hanage WP, Van Kerkhove MD, Hollingsworth TD, Griffin J, Baggaley RF et al.(2009). Pandemic Potential of a Strain of Influenza A (H1N1): Early Findings. Science vol. 324, (5934) 1557-1561.
Ghani AC, Sutherland CJ, Riley EM, Drakeley CJ, Griffin JT, Gosling RD, Filipe JAN(2009). Loss of population levels of immunity to malaria as a result of exposure-reducing interventions: Consequences for interpretation of disease trends. PLoS ONE vol. 4, (2)
Corran PH, Cook J, Lynch C, Leendertse H, Manjurano A, Griffin J, Cox J, Abeku T et al.(2008). Dried blood spots as a source of anti-malarial antibodies for epidemiological studies. Malaria Journal vol. 7,
Gras L, Kesselring AM, Griffin JT, Van Sighem AI, Fraser C, Ghani AC, Miedema F, Reiss P et al.(2007). CD4 cell counts of 800 cells/mm3 or greater after 7 years of highly active antiretroviral therapy are feasible in most patients starting with 350 cells/mm3 or greater. Journal of Acquired Immune Deficiency Syndromes vol. 45, (2) 183-192.
Griffin JT, Fraser C, Gras L, De Wolf F, Ghani AC(2006). The effect on treatment comparisons of different measurement frequencies in human immunodeficiency virus observational databases. American Journal of Epidemiology vol. 163, (7) 676-683.
Fidler S, Fraser C, Fox J, Tamm N, Griffin JT, Weber J(2006). Comparative potency of three antiretroviral therapy regimes in primary HIV infection. AIDS vol. 20, (2) 247-252.
Ghani AC, Donnelly CA, Cox DR, Griffin JT, Fraser C, Lam TH, Ho LM, Chan WS et al.(2005). Methods for estimating the case fatality ratio for a novel, emerging infectious disease. American Journal of Epidemiology vol. 162, (5) 479-486.
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