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Publications:  Dr Vidya Darbari

Darbari VC, Ciccone J, Patel JS, Islam B, Agarwal PK, Haider S(2020). Electrostatic Switching Controls Channel Dynamics of the Sensor Protein VirB10 in A. tumefaciens Type IV Secretion System. ACS Omega Article acsomega.9b03313,
Fenn K, Wong CT, Darbari VC(2020). Mycobacterium tuberculosis Uses Mce Proteins to Interfere With Host Cell Signaling. Frontiers in Molecular Biosciences vol. 6,
Glyde R, Fuzhou Y, DARBARI VC, Zhang N, Buck M, Zhang X(2017). Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation. Molecular Cell
Zhang N, Darbari VC, Glyde R, Zhang X, Buck M(2016). The bacterial enhancer-dependent RNA polymerase. Biochem J vol. 473, (21) 3741-3753.
Sawicka M, Wanrooij PH, Darbari VC, Tannous E, Hailemariam S, Bose D, Makarova AV, Burgers PM et al.(2016). The dimeric architecture of checkpoint Mec1ATR and Tel1ATM reveal a common structural organization. Journal of Biological Chemistry
Chandran Darbari V, Waksman G(2015). Structural biology of bacterial type IV secretion systems. Annual Reviews
Yang Y, Darbari VC, Zhang N, Lu D, Glyde R, Wang Y-P, Winkelman JT, Gourse RL et al.(2015). Structures of the RNA polymerase-σ54 reveal new and conserved regulatory strategies. Science vol. 349, Article 6250, 882-885.
Darbari VC, Lawton E, Lu D, Burrows PC, Wiesler S, Joly N, Zhang N, Zhang X et al.(2014). Molecular basis of nucleotide-dependent substrate engagement and remodeling by an AAA+ activator. Nucleic Acids Research vol. 42, (14) 9249-9261.
Rivera-Calzada A, Fronzes R, Savva CG, Chandran V, Lian PW, Laeremans T, Pardon E, Steyaert J et al.(2013). Structure of a bacterial type IV secretion core complex at subnanometre resolution. The EMBO journal vol. 32, Article 8, 1195-1204.
Chandran V(2013). Type IV secretion machinery: molecular architecture and function. Biochemical Society Transactions vol. 41, Article 1, 17-28.
Banta LM, Kerr JE, Cascales E, Giuliano ME, Bailey ME, McKay C, Chandran V, Waksman G et al.(2011). An Agrobacterium VirB10 mutation conferring a type IV secretion system gating defect. Journal of bacteriology vol. 193, Article 10, 2566-2574.
Nurmohamed S, Vincent HA, Titman CM, Chandran V, Pears MR, Du D, Griffin JL, Callaghan AJ et al.(2011). Polynucleotide phosphorylase activity may be modulated by metabolites in Escherichia coli. Journal of Biological Chemistry vol. 286, Article 16, 14315-14323.
Rêgo AT, Chandran V, Waksman G(2010). Two-step and one-step secretion mechanisms in Gram-negative bacteria: contrasting the type IV secretion system and the chaperone-usher pathway of pilus biogenesis. Biochemical Journal vol. 425, Article 3, 475-488.
Meng G, Fronzes R, Chandran V, Remaut H, Waksman G(2009). Protein oligomerization in the bacterial outer membrane (Review). Molecular membrane biology vol. 26, Article 3, 136-145.
Durand E, Verger D, Rêgo AT, Chandran V, Meng G, Fronzes R, Waksman G(2009). Structural biology of bacterial secretion systems in Gram-negative pathogens-potential for new drug targets. Infectious Disorders-Drug Targets (Formerly Current Drug Targets-Infectious Disorders) vol. 9, Article 5, 518-547.
Chandran V, Fronzes R, Duquerroy S, Cronin N, Navaza J, Waksman G(2009). Structure of the outer membrane complex of a type IV secretion system. Nature vol. 462, Article 7276, 1011-1015.
Chandran V, Poljak L, Vanzo NF, Leroy A, Miguel RNN, Fernandez-Recio J, Parkinson J, Burns C et al.(2007). Recognition and cooperation between the ATP-dependent RNA helicase RhlB and ribonuclease RNase E. Journal of molecular biology vol. 367, Article 1, 113-132.
Chandran V, Luisi BF(2006). Recognition of enolase in the Escherichia coli RNA degradosome. Journal of molecular biology vol. 358, Article 1, 8-15.
Chandran V (2006). Structural and functional characterisation of the protein-protein and protein-RNA interactions in the RNA degradosome.
Chandran V, Stollar EJ, Lindorff-Larsen K, Harper JF, Chazin WJ, Dobson CM, Luisi BF, Christodoulou J(2006). Structure of the regulatory apparatus of a calcium-dependent protein kinase (CDPK): a novel mode of calmodulin-target recognition. Journal of molecular biology vol. 357, Article 2, 400-410.
Marcaida MJ, DePristo MA, Chandran V, Carpousis AJ, Luisi BF(2006). The RNA degradosome: life in the fast lane of adaptive molecular evolution. Trends in biochemical sciences vol. 31, Article 7, 359-365.
Chandran V, Callaghan A, Long J, Zaid O, Aurikka J, Ilag L, Robinson C, Carpousis AJ et al. (2004). Protein-protein interactions in the RNA degradosome. PROTEIN SCIENCE. vol. 13, 144-144.
Dasgupta S, Chandran V, Bhinge A, Sewlikar S, Nimbkar A, Datta D(2004). Role of L-lysine HCl in adoptive immune therapy towards development of suitable tuberculosis vaccination. Indian journal of experimental biology vol. 42, Article 8, 758-765.
Callaghan AJ, Aurikko JP, Ilag LL, Grossmann JG, Chandran V, Kühnel K, Poljak L, Carpousis AJ et al.(2004). Studies of the RNA degradosome-organizing domain of the Escherichia coli ribonuclease RNase E. Journal of molecular biology vol. 340, Article 5, 965-979.
Calladine CR, Pratap V, Chandran V, Mizuguchi K, Luisi BF(2003). Cylindrical channels from concave helices. Science vol. 299, Article 5607, 661-662.
Dasgupta S, Bhinge A, Chandran V, Sewlikar S, Nimbkar A, Datta D(2003). Role of L-lysine HCl in immunopotentiation towards development of suitable tuberculosis vaccination. Vaccine vol. 21, Article 32, 4722-4727.
Datta D, Bhinge A, Chandran V(2001). Lysine: Is it worth more?. Cytotechnology vol. 36, Article 1-3, 3-32.
Datta D, Kundu PK, Biswas S, Dasgupta S, Bhinge A, Chandran V(2000). Effect of cationic amino acid, l-lysine and its polymers on the growth and secretion of hybridoma cell line OKT-3. Hybridoma vol. 19, Article 4, 339-346.
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