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Publications:  Dr Zuzana Licenikova Horejsi

von Morgen P, Lidak T, Horejsi Z, Macurek L(2018). Nuclear localisation of 53BP1 is regulated by phosphorylation of the nuclear localisation signal. Biol Cell vol. 110, (6) 137-146.
10.1111/boc.201700067
https://qmro.qmul.ac.uk/xmlui/handle/123456789/54772
von Morgen P, Burdova K, Flower TG, O'Reilly NJ, Boulton SJ, Smerdon SJ, Macurek L, Ho¿ejší Z(2017). MRE11 stability is regulated by CK2-dependent interaction with R2TP complex. Oncogene vol. 36, (34) 4943-4950.
10.1038/onc.2017.99
Malinová A, Cva¿ková Z, Mat¿j¿ D, Ho¿ejší Z, Abéza C, Vandermoere F, Bertrand E, Stan¿k D et al.(2017). Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones. J Cell Biol vol. 216, (6) 1579-1596.
10.1083/jcb.201701165
Hiraga S-I, Ly T, Garzón J, Ho¿ejší Z, Ohkubo Y-N, Endo A, Obuse C, Boulton SJ et al.(2017). Human RIF1 and protein phosphatase 1 stimulate DNA replication origin licensing but suppress origin activation. EMBO Rep vol. 18, (3) 403-419.
10.15252/embr.201641983
von Morgen P, Ho¿ejší Z, Macurek L(2015). Substrate recognition and function of the R2TP complex in response to cellular stress. Front Genet vol. 6,
10.3389/fgene.2015.00069
Ho¿ejší Z, Stach L, Flower TG, Joshi D, Flynn H, Skehel JM, O'Reilly NJ, Ogrodowicz RW et al.(2014). Phosphorylation-dependent PIH1D1 interactions define substrate specificity of the R2TP cochaperone complex. Cell Rep vol. 7, (1) 19-26.
10.1016/j.celrep.2014.03.013
Kulkarni A, Oza J, Yao M, Sohail H, Ginjala V, Tomas-Loba A, Horejsi Z, Tan AR et al.(2013). Tripartite Motif-containing 33 (TRIM33) protein functions in the poly(ADP-ribose) polymerase (PARP)-dependent DNA damage response through interaction with Amplified in Liver Cancer 1 (ALC1) protein. J Biol Chem vol. 288, (45) 32357-32369.
10.1074/jbc.M113.459164
Adelman CA, Lolo RL, Birkbak NJ, Murina O, Matsuzaki K, Horejsi Z, Parmar K, Borel V et al.(2013). HELQ promotes RAD51 paralogue-dependent repair to avert germ cell loss and tumorigenesis. Nature vol. 502, (7471) 381-384.
10.1038/nature12565
Horejsí Z, Takai H, Adelman CA, Collis SJ, Flynn H, Maslen S, Skehel JM, de Lange T et al.(2010). CK2 phospho-dependent binding of R2TP complex to TEL2 is essential for mTOR and SMG1 stability. Mol Cell vol. 39, (6) 839-850.
10.1016/j.molcel.2010.08.037
Adamo A, Collis SJ, Adelman CA, Silva N, Horejsi Z, Ward JD, Martinez-Perez E, Boulton SJ et al.(2010). Preventing nonhomologous end joining suppresses DNA repair defects of Fanconi anemia. Mol Cell vol. 39, (1) 25-35.
10.1016/j.molcel.2010.06.026
Novakova Z, Hubackova S, Kosar M, Janderova-Rossmeislova L, Dobrovolna J, Vasicova P, Vancurova M, Horejsi Z et al.(2010). Cytokine expression and signaling in drug-induced cellular senescence. Oncogene vol. 29, (2) 273-284.
10.1038/onc.2009.318
Ahel D, Horejsí Z, Wiechens N, Polo SE, Garcia-Wilson E, Ahel I, Flynn H, Skehel M et al.(2009). Poly(ADP-ribose)-dependent regulation of DNA repair by the chromatin remodeling enzyme ALC1. Science vol. 325, (5945) 1240-1243.
10.1126/science.1177321
Horej¿í Z, Collis SJ, Boulton SJ(2009). FANCM-FAAP24 and HCLK2: roles in ATR signalling and the Fanconi anemia pathway. Cell Cycle vol. 8, (8) 1133-1137.
10.4161/cc.8.8.8204
Collis SJ, Ciccia A, Deans AJ, Horejsí Z, Martin JS, Maslen SL, Skehel JM, Elledge SJ et al.(2008). FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex. Mol Cell vol. 32, (3) 313-324.
10.1016/j.molcel.2008.10.014
Bartkova J, Horejsí Z, Sehested M, Nesland JM, Rajpert-De Meyts E, Skakkebaek NE, Stucki M, Jackson S et al.(2007). DNA damage response mediators MDC1 and 53BP1: constitutive activation and aberrant loss in breast and lung cancer, but not in testicular germ cell tumours. Oncogene vol. 26, (53) 7414-7422.
10.1038/sj.onc.1210553
Bartkova J, Horejsí Z, Koed K, Krämer A, Tort F, Zieger K, Guldberg P, Sehested M et al.(2005). DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis. Nature vol. 434, (7035) 864-870.
10.1038/nature03482
Horejsí Z, Falck J, Bakkenist CJ, Kastan MB, Lukas J, Bartek J(2004). Distinct functional domains of Nbs1 modulate the timing and magnitude of ATM activation after low doses of ionizing radiation. Oncogene vol. 23, (17) 3122-3127.
10.1038/sj.onc.1207447
Pajer P, Pecenka V, Karafiát V, Králová J, Horejsí Z, Dvorák M(2003). The twist gene is a common target of retroviral integration and transcriptional deregulation in experimental nephroblastoma. Oncogene vol. 22, (5) 665-673.
10.1038/sj.onc.1206105
Karafiát V, Dvoráková M, Pajer P, Králová J, Horejsí Z, Cermák V, Bart¿nek P, Zenke M et al.(2001). The leucine zipper region of Myb oncoprotein regulates the commitment of hematopoietic progenitors. Blood vol. 98, (13) 3668-3676.
10.1182/blood.v98.13.3668
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