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Publications:  Dr Louisa James

Bucaite G, Kang-Pettinger T, Moreira J, Gould HJ, James LK, Sutton BJ, McDonnell JM(2019). Interplay between affinity and valency in effector cell degranulation: A model system with polcalcin allergens and human patient–derived IgE antibodies. Journal of Immunology vol. 203, (7) 1693-1700.
Gould HJ, James LK(2019). Orchestration of immunoglobulin isotypes, subclasses, and specificities in patients receiving intravenous IgG or subcutaneous immunotherapy and those with chronic rhinosinusitis with nasal polyps: Toward precision medicine. Journal of Allergy and Clinical Immunology
Baker D, Pryce G, James LK, Schmierer K, Giovannoni G(2019). Failed B cell survival factor trials support the importance of memory B cells in multiple sclerosis. European Journal of Neurology
Upton NEG, Hayday TS, James LK(2019). Isolation and characterization of lymphocytes from human mucosal biopsies. Methods in Molecular Biology, vol. 2020,
Mitropoulou AN, Bowen H, Dodev TS, Davies AM, Bax HJ, Beavil RL, Beavil AJ, Gould HJ et al.(2018). Structure of a patient-derived antibody in complex with allergen reveals simultaneous conventional and superantigen-like recognition. Proceedings of the National Academy of Sciences of the United States of America vol. 115, (37) E8707-E8716.
Dhaliwal B, Pang MOY, Keeble AH, James LK, Gould HJ, McDonnell JM, Sutton BJ, Beavil AJ(2017). IgE binds asymmetrically to its B cell receptor CD23. Scientific Reports vol. 7,
Chen J-B, James LK, Davies AM, Wu Y-CB, Rimmer J, Lund VJ, Chen J-H, McDonnell JM et al.(2017). Antibodies and superantibodies in patients with chronic rhinosinusitis with nasal polyps. Journal of Allergy and Clinical Immunology vol. 139, (4) 1195-1204.e11.
James LK, Till SJ(2016). Potential Mechanisms for IgG4 Inhibition of Immediate Hypersensitivity Reactions. Current Allergy and Asthma Reports vol. 16, (3) Article 23,
James LK(2016). The Cloning and Expression of Human Monoclonal Antibodies: Implications for Allergen Immunotherapy. Current Allergy and Asthma Reports vol. 16, (2) Article 15,
Steveling EH, Lao-Araya M, Koulias C, Scadding G, Eifan A, James LK, Dumitru A, Penagos M et al.(2015). Protocol for a randomised, double-blind, placebo-controlled study of grass allergen immunotherapy tablet for seasonal allergic rhinitis: time course of nasal, cutaneous and immunological outcomes. Clinical and Translational Allergy vol. 5, (1) Article 43,
Gadermaier E, James LK, Shamji MH, Blatt K, Fauland K, Zieglmayer P, Garmatiuk T, Focke-Tejkl M et al.(2016). Epitope specificity determines cross-protection of a SIT-induced IgG4antibody. Allergy vol. 71, (1) 36-46.
Santos AF, James LK, Bahnson HT, Shamji MH, Couto-Francisco NC, Islam S, Houghton S, Clark AT et al.(2015). IgG4 inhibits peanut-induced basophil and mast cell activation in peanut-tolerant children sensitized to peanut major allergens. Journal of Allergy and Clinical Immunology vol. 135, (5) 1249-1256.
Dodev TS, Bowen H, Shamji MH, Bax HJ, Beavil AJ, McDonnell JM, Durham SR, Sutton BJ et al.(2015). Inhibition of allergen-dependent IgE activity by antibodies of the same specificity but different class. Allergy vol. 70, (6) 720-724.
Wu Y-CB, James LK, Vander Heiden JA, Uduman M, Durham SR, Kleinstein SH, Kipling D, Gould HJ(2014). Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis. Journal of Allergy and Clinical Immunology vol. 134, (3) 604-612.
Dodev TS, Karagiannis P, Gilbert AE, Josephs DH, Bowen H, James LK, Bax HJ, Beavil R et al.(2015). A tool kit for rapid cloning and expression of recombinant antibodies. Scientific Reports vol. 4, (1) Article 5885,
James LK, Bowen H, Calvert RA, Dodev TS, Shamji MH, Beavil AJ, McDonnell JM, Durham SR et al.(2012). Allergen specificity of IgG4-expressing B cells in patients with grass pollen allergy undergoing immunotherapy. Journal of Allergy and Clinical Immunology vol. 130, (3) 663-670.e3.
Shamji MH, James LK, Durham SR(2011). Serum Immunologic Markers for Monitoring Allergen-Specific Immunotherapy. Immunology and Allergy Clinics of North America vol. 31, (2) 311-323.
James LK, Shamji MH, Walker SM, Wilson DR, Wachholz PA, Francis JN, Jacobson MR, Kimber I et al.(2011). Long-term tolerance after allergen immunotherapy is accompanied by selective persistence of blocking antibodies. Journal of Allergy and Clinical Immunology vol. 127, (2) 509-516.e5.
James LK, Durham SR(2009). Rhinitis with negative skin tests and absent serum allergen-specific IgE: More evidence for local IgE?. Journal of Allergy and Clinical Immunology vol. 124, (5) 1012-1013.
Thrower SL, James L, Hall W, Green KM, Arif S, Allen JS, Van-Krinks C, Lozanoska-Ochser B et al.(2009). Proinsulin peptide immunotherapy in type 1 diabetes: Report of a first-in-man Phase I safety study. Clinical and Experimental Immunology vol. 155, (2) 156-165.
James LK, Durham SR(2008). Update on mechanisms of allergen injection immunotherapy. Clinical & Experimental Allergy vol. 38, (7) 1074-1088.
Francis JN, James LK, Paraskevopoulos G, Wong C, Calderon MA, Durham SR, Till SJ(2008). Grass pollen immunotherapy: IL-10 induction and suppression of late responses precedes IgG4 inhibitory antibody activity. Journal of Allergy and Clinical Immunology vol. 121, (5) 1120-1125.e2.
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