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Research

Publications: Dr Lakxmi Subramanian

Chik JK, Moiseeva V, Goel PK, Meinen BA, Koldewey P, An S, Mellone BG, Subramanian L et al. ( 2019 ) . Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functions for the inner pocket . Journal of Biological Chemistryjbc.RA119.008464 - jbc.RA119.008464 .
An S, Koldewey P, Chik J, SUBRAMANIAN L, Cho U-S ( 2018 ) . Mis16 Switches Function from a Histone H4 Chaperone to a CENP-ACnp1-Specific Assembly Factor through Eic1 Interaction . Structure
Subramanian L, Medina-Pritchard B, Barton R, Spiller F, Kulasegaran-Shylini R, Radaviciute G, Allshire RC, Arockia Jeyaprakash A ( 2016 ) . Centromere localization and function of Mis18 requires Yippee-like domain-mediated oligomerization . EMBO Reports vol. 17 , ( 4 ) 496 - 507 .
Gal C, Murton HE, Subramanian L, Whale AJ, Moore KM, Paszkiewicz K, Codlin S, Bähler J et al. ( 2016 ) . Abo1, a conserved bromodomain AAA-ATPase, maintains global nucleosome occupancy and organisation . EMBO Reports vol. 17 , ( 1 ) 79 - 93 .
Pai CC, Deegan RS, Subramanian L, Gal C, Sarkar S, Blaikley EJ, Walker C, Hulme L et al. ( 2014 ) . A histone H3K36 chromatin switch coordinates DNA double-strand break repair pathway choice . Nature Communications vol. 5 ,
Subramanian L, Toda NRT, Rappsilber J, Allshire RC ( 2014 ) . Eic1 links Mis18 with the CCAN/Mis6/Ctf19 complex to promote CENP-A assembly . Open Biology vol. 4 , ( APRIL )
Lando D, Endesfelder U, Berger H, Subramanian L, Dunne PD, McColl J, Klenerman D, Carr AM et al. ( 2012 ) . Quantitative single-molecule microscopy reveals that CENP-A<sup>Cnp1</sup> deposition occurs during G2 in fission yeast . Open Biology vol. 2 , ( JULY )
Khair L, Chang YT, Subramanian L, Russell P, Nakamura TM ( 2010 ) . Roles of the checkpoint sensor clamp Rad9-Rad1-Hus1 (911)-complex and the clamp loaders Rad17-RFC and Ctf18-RFC in Schizosaccharomyces pombe telomere maintenance . Cell Cycle vol. 9 , ( 11 ) 2237 - 2248 .
Subramanian L, Nakamura TM ( 2010 ) . To fuse or not to fuse: How do checkpoint and DNA repair proteins maintain telomeres? . Frontiers in Bioscience vol. 15 , ( 3 ) 1105 - 1118 .
Khair L, Subramanian L, Moser BA, Nakamura TM ( 2010 ) . Roles of heterochromatin and telomere proteins in regulation of fission yeast telomere recombination and telomerase recruitment . J Biol Chem vol. 285 , ( 8 ) 5327 - 5337 .
Subramanian L, Nakamura TM ( 2010 ) . A kinase-independent role for the rad3<sup>ATR</sup>-Rad26<sup>ATRIP</sup> complex in recruitment of Tel1<sup>ATM</sup> to telomeres in fission yeast . PLoS Genetics vol. 6 , ( 2 )
Moser BA, Subramanian L, Khair L, Chang YT, Nakamura TM ( 2009 ) . Fission yeast Tel1<sup>ATM</sup> and Rad3<sup>ATR</sup> promote telomere protection and telomerase recruitment . PLoS Genetics vol. 5 , ( 8 )
Moser BA, Subramanian L, Chang YT, Noguchi C, Noguchi E, Nakamura TM ( 2009 ) . Differential arrival of leading and lagging strand DNA polymerases at fission yeast telomeres . EMBO Journal vol. 28 , ( 7 ) 810 - 820 .
Subramanian L, Moser BA, Nakamura TM ( 2008 ) . Recombination-based telomere maintenance is dependent on Tel1-MRN and Rap1 and inhibited by telomerase, Taz1, and Ku in fission yeast . Molecular and Cellular Biology vol. 28 , ( 5 ) 1443 - 1455 .
Suseendranathan K, Sengupta K, Rikhy R, D'Souza JS, Kokkanti M, Kulkarni MG, Kamdar R, Changede R et al. ( 2007 ) . Expression pattern of Drosophila translin and behavioral analyses of the mutant . European Journal of Cell Biology vol. 86 , ( 3 ) 173 - 186 .