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Research

Publications: Ms Cristina Perez Ternero

Lowe VJ, Aubdool AA, Moyes AJ, Dignam JP, Perez-Ternero C, Baliga RS, Smart N, Hobbs AJ ( 2024 ) . Cardiomyocyte-derived C-type natriuretic peptide diminishes myocardial ischaemic injury by promoting revascularisation and limiting fibrotic burden . Pharmacological Research vol. 209 ,
Andresen H, Pérez‐Ternero C, Robinson J, Dickey DM, Hobbs AJ, Potter LR, Levy FO, Cataliotti A et al. ( 2023 ) . Novel enhancers of guanylyl cyclase‐A activity acting via allosteric modulation . British Journal of Pharmacology vol. 180 , ( 24 ) 3254 - 3270 .
Dignam JP, Perez-Ternero C, Aubdool AA, Hobbs AJ ( 2023 ) . C-Type Natriuretic Peptide Signalling Attenuates the Development of Pulmonary Hypertension and Right Ventricular Remodelling . Presented at: A14. THIS IS GETTING COMPLICATED: EPIGENETICS, -OMICS, AND CELL SIGNALING IN PULMONARY HYPERTENSION ,
Moyes A, Sand C, Aubdool A, Perez-Ternero C, Mohammad S, Thiemermann C, Hobbs A ( 2023 ) . C-type Natriuretic Peptide Attenuates Endothelial and Cardiac Dysfunction During Endotoxemia and Polymicrobial Sepsis . Conference: B45. NEW STUDIES IN SEPSIS AND INFECTIOUS DISEASESa3433 - a3433 .
Dignam JP, Perez-Ternero C, Aubdool A, Hobbs AJ ( 2023 ) . C-type natriuretic peptide offsets the development of pulmonary hypertension . JOURNAL OF TRANSLATIONAL MEDICINE . vol. 21 ,
Perez-Ternero C, Aubdool A, Makwana R, Sanger G, Stimson R, Chan L, Moyes A, Hobbs A ( 2023 ) . C-type natriuretic peptide regulates metabolic homeostasis . JOURNAL OF TRANSLATIONAL MEDICINE . vol. 21 ,
Andresen H, Perez-Ternero C, Robinson J, Dickey D, Hobbs A, Potter LR, Levy FO, Cataliotti A et al. ( 2023 ) . Small molecules enhance natriuretic peptide activity through a novel allosteric site on the natriuretic peptide receptor guanylyl cyclase-A . JOURNAL OF TRANSLATIONAL MEDICINE . vol. 21 ,
Dignam JP, Perez-Ternero C, Aubdool A, Hobbs AJ ( 2023 ) . C-type natriuretic peptide offsets the development of pulmonary hypertension . JOURNAL OF TRANSLATIONAL MEDICINE . vol. 21 ,
Perez-Ternero C, Li W, Aubdool A, Goldin R, Alazawi W, Hobbs A ( 2023 ) . C-type natriuretic peptide protects against the development of non-alcoholic steatohepatitis and portal hypertension . BRITISH JOURNAL OF PHARMACOLOGY . vol. 180 , 6 - 7 .
Perez-Ternero C, Aubdool A, Makwana R, Sanger G, Stimson R, Chan L, Moyes A, Hobbs A ( 2023 ) . C-type natriuretic peptide regulates metabolic homeostasis . JOURNAL OF TRANSLATIONAL MEDICINE . vol. 21 ,
Andresen H, Perez-Ternero C, Robinson J, Dickey D, Hobbs A, Potter LR, Levy FO, Cataliotti A et al. ( 2023 ) . Small molecules enhance natriuretic peptide activity through a novel allosteric site on the natriuretic peptide receptor guanylyl cyclase-A . JOURNAL OF TRANSLATIONAL MEDICINE . vol. 21 ,
Perez-Ternero C, Pallier PN, Tremoleda JL, Delogu A, Fernandes C, Michael-Titus AT, Hobbs AJ ( 2022 ) . C-type natriuretic peptide preserves central neurological function by maintaining blood-brain barrier integrity . Frontiers in Molecular Neuroscience vol. 15 ,
Zarenkiewicz J, Perez-Ternero C, Kojasoy V, McGinity C, Khodade VS, Lin J, Tantillo DJ, Toscano JP et al. ( 2022 ) . The reaction of hydropersulfides (RSSH) with S-nitrosothiols (RS-NO) and the biological/physiological implications . Free Radical Biology and Medicine vol. 188 , 459 - 467 .
Smith RJ, Perez-Ternero C, Conole D, Martin C, Myers SH, Hobbs AJ, Selwood DL ( 2022 ) . A Series of Substituted Bis-Aminotriazines Are Activators of the Natriuretic Peptide Receptor C . Journal of Medicinal Chemistry vol. 65 , ( 7 ) 5495 - 5513 .
Perez-Ternero C, Aubdool AA, Makwana R, Sanger GJ, Stimson RH, Chan LF, Moyes AJ, Hobbs AJ ( 2022 ) . C-type natriuretic peptide is a pivotal regulator of metabolic homeostasis . Proceedings of the National Academy of Sciences of the United States of America vol. 119 , ( 13 )
Fukuto JM, Perez-Ternero C, Zarenkiewicz J, Lin J, Hobbs AJ, Toscano JP ( 2022 ) . Hydropersulfides (RSSH) and Nitric Oxide (NO) Signaling: Possible Effects on S-Nitrosothiols (RS-NO) . Antioxidants vol. 11 , ( 1 )
Grange RMH, Preedy MEJ, Renukanthan A, Dignam JP, Lowe VJ, Moyes AJ, Pérez‐Ternero C, Aubdool AA et al. ( 2021 ) . Multidrug resistance proteins preferentially regulate natriuretic peptide‐driven cGMP signalling in the heart and vasculature . British Journal of Pharmacology vol. 179 , ( 11 ) 2443 - 2459 .
Perez-Ternero C, Aubdool AA, Moyes AJ, Hobbs AJ ( 2019 ) . C-Type Natriuretic Peptide (CNP) Regulates Adipogenesis, Thermogenesis and Glucose Sensitivity via Natriuretic Peptide Receptor (NPR)-C Signalling . CIRCULATION . Conference: American Heart Association vol. 140 ,
Ternero CP, Macià A, Parrado J, Motilva MJ, de Sotomayor MA, Herrera MD ( 2017 ) . Rice bran enzymatic extract, a source of ferulic acid, protects endothelial function and inhibits NADPHox activity . Atherosclerosis vol. 263 , e76 - e77 .
Perez-Ternero C, Werner CM, Nickel AG, Herrera MD, Motilva M-J, Böhm M, de Sotomayor MA, Laufs U ( 2017 ) . Ferulic acid, a bioactive component of rice bran, improves oxidative stress and mitochondrial biogenesis and dynamics in mice and in human mononuclear cells . The Journal of Nutritional Biochemistry vol. 48 , 51 - 61 .
Perez-Ternero C, Macià A, de Sotomayor MA, Parrado J, Motilva M-J, Herrera M-D ( 2017 ) . Bioavailability of the ferulic acid-derived phenolic compounds of a rice bran enzymatic extract and their activity against superoxide production . Food Funct vol. 8 , ( 6 ) 2165 - 2174 .
Perez-Ternero C, Alvarez de Sotomayor M, Herrera MD ( 2017 ) . Contribution of ferulic acid, γ-oryzanol and tocotrienols to the cardiometabolic protective effects of rice bran . Journal of Functional Foods vol. 32 , 58 - 71 .
Perez-Ternero C, Macià A, de Sotomayor MA, Parrado J, Motilva M-J, Herrera M-D ( 2017 ) . Bioavailability of the ferulic acid-derived phenolic compounds of a rice bran enzymatic extract and their activity against superoxide production . Food & Function vol. 8 , ( 6 ) 2165 - 2174 .
Perez-Ternero C, Claro C, Parrado J, Herrera MD, de Sotomayor MA ( 2016 ) . Rice bran enzymatic extract reduces atherosclerotic plaque development and steatosis in high-fat fed ApoE−/− mice . Nutrition vol. 37 , 22 - 29 .
Perez-Ternero C, Pulgarin BB, de Sotomayor MA, Herrera MD ( 2016 ) . Atherosclerosis-related inflammation and oxidative stress are improved by rice bran enzymatic extract . Journal of Functional Foods vol. 26 , 610 - 621 .
Perez Ternero C ( 2016 ) . INCREASED OXIDATIVE STRESS AND IMPAIRED MITOCHONDRIAL BIOGENESIS AND DYNAMICS ARE IMPROVED BY RICE BRAN ENZYMATIC EXTRACT DIET SUPPLEMENTATION .
Perez-Ternero C, Rodriguez-Rodriguez R, Herrera MD, de Sotomayor MA ( 2016 ) . Diet supplementation with rice bran enzymatic extract restores endothelial impairment and wall remodelling of ApoE −/− mice microvessels . Atherosclerosis vol. 250 , 15 - 22 .
Werner C, Perez-Ternero C, Nickel A, Kasakov A, Jakob S, Haendeler J, Altschmied J, Boehm M et al. ( 2016 ) . Telomerase deficiency is associated with impaired diastolic function, mitochondrial dysfunction and increased fibrosis in a murine model of cardiac pressure overload . EUROPEAN HEART JOURNAL . vol. 37 , 423 - 423 .
Perez-Ternero C, Herrera MD, Laufs U, Alvarez de Sotomayor M, Werner C ( 2015 ) . Food supplementation with rice bran enzymatic extract prevents vascular apoptosis and atherogenesis in ApoE−/− mice . European Journal of Nutrition vol. 56 , ( 1 ) 225 - 236 .
Ternero CP, Claro C, de Sotomayor MA, Herrera MD ( 2015 ) . Rice bran enzymatic extract prevents atherosclerotic plaque development through its hipolipidemic and antiinflamatory effects . Atherosclerosis . vol. 241 ,
Perez Ternero C, Werner C, Parrado J, Alvarez de Sotomayor M, Herrera MD, Laufs U ( 2015 ) . FOOD SUPPLEMENTATION WITH RICE BRAN ENZYMATIC EXTRACT PREVENTS VASCULAR SENESCENCE AND ATHEROGENESIS IN APOE-/-MICE . ATHEROSCLEROSIS . vol. 241 , E57 - E57 .
Alvarez de Sotomayor M, Perez-Ternero C, Parrado J, Herrera MD ( 2015 ) . RICE BRAN ENZYMATIC EXTRACT DIET SUPPLEMENTATION REDUCES OXIDATIVE STRESS AND INFLAMMATION ASSOCIATED TO ATHEROSCLEROSIS DISEASE IN APOE<SUP>-/-</SUP> MICE . BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY . vol. 117 , 26 - 26 .
Perez-Ternero C, Rodriguez-Rodriguez R, Alvarez de Sotomayor M, Herrera MD ( 2015 ) . RICE BRAN ENZYMATIC EXTRACT PREVENTS ENDOTHELIAL DYSFUNCTION AND RESTORES STRUCTURAL, MECHANICAL AND MYOGENIC ALTERATIONS OF RESISTANCE ARTERIES IN APOE<SUP>-/-</SUP> MICE . BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY . vol. 117 , 19 - 19 .
Ternero CP, Claro C, Rodriguez-Rodriguez R, de Sotomayor MA, Herrera MD ( 2014 ) . Rice bran enzymatic extract reduces oxidative stress and restores mesenteric endothelium dependant dilatation in apo e (-/-) mice . Atherosclerosis . vol. 235 ,
Perez-Ternero C, Claro C, Parrado J, Herrera MD, Alvarez de Sotomayor M ( 2014 ) . RICE BRAN ENZYMATIC EXTRACT REDUCES ATHEROSCLEROTIC LESIONS IN APO E (-/-) MICE . BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY . vol. 115 , 12 - 12 .
Perez-Ternero C, Rodriguez-Rodriguez R, Parrado J, de Sotomayor MA ( 2013 ) . Grape pomace enzymatic extract restores vascular dysfunction evoked by endothelin-1 and DETCA via NADPH oxidase downregulation and SOD activation . Journal of Functional Foods vol. 5 , ( 4 ) 1673 - 1683 .
Perez-Ternero C, Rodriguez-Rodriguez R, Parrado J, Herrera MD, Alvarez de Sotomayor M ( 2013 ) . ANTIOXIDANT PROTECTION OF GRAPE POMACE ENZYMATIC EXTRACT AND ITS MAJOR POLYPHENOLS UPON NADPH OXIDASE ACTIVATION AND SUPEROXIDE DISMUTASE INHIBITION . BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY . vol. 113 , 21 - 21 .