Publications:  Dr Kevin Rouault-Pierre

Rio-Machin A, Casado-Izquierdo P, Miettinen J, Bewicke-Copley F, Khan N, Demeulemeester J, Krizsán S, Zheng J et al.(2020). Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia. Blood vol. 136, (Supplement 1) 39-40.

Caye A, Rouault-Pierre K, Strullu M, Lainey E, Abarrategi A, Fenneteau O, Arfeuille C, Osman J et al.(2020). Correction: Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment (Leukemia, (2020), 34, 6, (1658-1668), 10.1038/s41375-019-0662-y). Leukemia vol. 34, (7)

Caye A, Rouault-Pierre K, Strullu M, Lainey E, Abarrategi A, Fenneteau O, Arfeuille C, Osman J et al.(2020). Despite mutation acquisition in hematopoietic stem cells, JMML-propagating cells are not always restricted to this compartment. Leukemia vol. 34, (6) 1658-1668.

Waclawiczek A, Hamilton A, Rouault-Pierre K, Abarrategi A, Albornoz MG, Miraki-Moud F, Bah N, Gribben J et al.(2020). Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia. Journal of Clinical Investigation vol. 130, (6) 3038-3050.

Jaud M, Philippe C, Di Bella D, Tang W, Pyronnet S, Laurell H, Mazzolini L, Rouault-Pierre K et al.(2020). Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers. Cells vol. 9, (3)

Saunderson EA, Rouault-Pierre K, Gribben JG, Ficz G(2019). CRISPR/Cas9-Targeted De Novo DNA Methylation Is Maintained and Impacts the Colony Forming Potential of Human Hematopoietic CD34+ Cells. Blood vol. 134, (Supplement_1) 2517-2517.

Abarrategi A, Gambera S, Alfranca A, Rodriguez-Milla MA, Perez-Tavarez R, Rouault-Pierre K, Waclawiczek A, Chakravarty P et al.(2018). c-Fos induces chondrogenic tumor formation in immortalized human mesenchymal progenitor cells. Scientific Reports vol. 8, (1)

Abarrategi A, Mian SA, Passaro D, Rouault-Pierre K, Grey W, Bonnet D(2018). Modeling the human bone marrow niche in mice: From host bone marrow engraftment to bioengineering approaches. Journal of Experimental Medicine vol. 215, (3) 729-743.

Mian SA, Rouault-Pierre K, Smith AE, Abarrategi A, Coats T, McLornan D, Mufti G, Bonnet D (2017). Bone Marrow Stem Cells from Patients with Myelodysplastic Syndrome (MDS) Engraft and Migrate in-between the Humanized Niches in Immuno-Compromised Mouse Models. BLOOD. vol. 130,

Di Tullio A, Rouault-Pierre K, Abarrategi A, Mian S, Grey W, Gribben J, Stewart A, Blackwood E et al.(2017). The combination of CHK1 inhibitor with G-CSF overrides cytarabine resistance in human acute myeloid leukemia. Nat Commun vol. 8, (1) 1679-1679.

Mian S, Rouault-Pierre K, Goulard M, Fenaux P, Dosquet C, Mufti G, Bonnet D(2017). Preclinical modeling of myelodysplastic syndromes. Experimental Hematology vol. 53,

Waclawiczek A, Hamilton A, Rouault-Pierre K, Abarrategi A, Bonnet D(2017). Regulation of human stem and progenitor cells by acute myeloid leukaemia in the human niche. Experimental Hematology vol. 53,

Passaro D, Di Tullio A, Abarrategi A, Rouault-Pierre K, Foster K, Ariza-McNaughton L, Montaner B, Chakravarty P et al.(2017). Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Disease Progression and Drug Response in Acute Myeloid Leukemia. Cancer Cell vol. 32, (3) 324-341.e6.

Das A, Rouault-Pierre K, Kamdar S, Gomez-Tourino I, Wood K, Donaldson I, Mein CA, Bonnet D et al.(2017). Adaptive from Innate: Human IFN-γ+CD4+T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults. J Immunol vol. 199, (5) 1696-1705.

Di Tullio A, Passaro D, Rouault-Pierre K, Purewal S, Bonnet D(2017). Nuclear Factor Erythroid 2 Regulates Human HSC Self-Renewal and T Cell Differentiation by Preventing NOTCH1 Activation. Stem Cell Reports vol. 9, (1) 5-11.

Passaro D, Di Tullio A, Abarrategi A, Rouault-Pierre K, Foster K, Ariza-McNaughton L, Chakravarty P, Bhaw L et al. (2017). ACUTE MYELOID LEUKEMIA ALTERS THE PERMEABILITY OF THE BONE MARROW VASCULAR MICROENVIRONMENT, FOSTERING DISEASE PROGRESSION AND DRUG RESISTANCE. HAEMATOLOGICA. vol. 102, 78-78.

Rouault-Pierre K, Smith AE, Mian SA, Pizzitola I, Kulasekararaj AG, Mufti GJ, Bonnet D(2017). Myelodysplastic syndrome can propagate from the multipotent progenitor compartment. Haematologica vol. 102, (1) e7-e10.

Rouault-Pierre K, Mian SA, Goulard M, Abarrategi A, Di Tulio A, Smith AE, Mohamedali A, Best S et al.(2017). Preclinical modeling of myelodysplastic syndromes. Leukemia vol. 31, (12) 2702-2708.

Passaro D, Di Tullio A, Abarrategi A, Rouault-Pierre K, Foster K, McNaughton LA, Lassailly F, Bonnet D (2016). Increased Vascular Permeability in the Bone Marrow Microenvironment Contributes to Acute Myeloid Leukemia Progression and Drug Response. Blood. vol. 128, 2662-2662.

Rouault-Pierre K, Hamilton A, Bonnet D(2016). Effect of hypoxia-inducible factors in normal and leukemic stem cell regulation and their potential therapeutic impact. Expert Opinion on Biological Therapy vol. 16, (4) 463-476.

Mian SA, Rouault-Pierre K, Smith AE, Seidl T, Pizzitola I, Kizilors A, Kulasekararaj AG, Bonnet D et al.(2015). SF3B1 mutant MDS-initiating cells may arise from the haematopoietic stem cell compartment. Nature Communications vol. 6,

Foster K, Lassailly F, Anjos-Afonso F, Currie E, Rouault-Pierre K, Bonnet D(2015). Different motile behaviors of human hematopoietic stem versus progenitor cells at the osteoblastic niche. Stem Cell Reports vol. 5, (5) 690-701.

Tettamanti S, Pizzitola I, Marin V, Anjos-Afonso F, Rouault-Pierre K, Lassailly F, Spinelli O, Biondi A et al. (2015). Chimeric Antigen Receptors for Specific Targeting of Acute Myeloid Leukemia. ANNALS OF HEMATOLOGY. vol. 94, 55-56.

Das A, Furness C, White A, Hayday T, Rouault-Pierre K, Greaves M, Hayday AC, Gibbons DL (2014). T-cell production of interleukin-8 (CXCL8) is enriched in recent thymic emigrants. IMMUNOLOGY. vol. 143, 46-47.

Pizzitola I, Anjos-Afonso F, Rouault-Pierre K, Lassailly F, Tettamanti S, Biondi A, Biagi E, Bonnet D (2014). Chimeric Antigen Receptor for Specific Targeting of Acute Myeloid Leukaemia. JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY. vol. 36, 324-325.

Griessinger E, Anjos-Afonso F, Pizzitola I, Rouault-Pierre K, Vargaftig J, Taussig D, Gribben J, Lassailly F et al.(2014). A niche-like culture system allowing the maintenance of primary human acute myeloid leukemia-initiating cells: A new tool to decipher their chemoresistance and self-renewal mechanisms. Stem Cells Translational Medicine vol. 3, (4) 520-529.

Pizzitola I, Anjos-Afonso F, Rouault-Pierre K, Lassailly F, Tettamanti S, Spinelli O, Biondi A, Biagi E et al.(2014). Chimeric antigen receptors against CD33/CD123 antigens efficiently target primary acute myeloid leukemia cells in vivo. Leukemia vol. 28, (8) 1596-1605.

Mian SA, Rouault-Pierre K, Smith AE, Seidl T, Kulasekararaj AG, Mohamedali AM, Shinde S, Bonnet D et al. (2013). SF3B1 Mutant Clones From Patients With Refractory Anaemia With Ringed Sideroblasts (RARS) Originate From The Early Haematopoietic Stem Cells and Maintain Their Engraftment Potential. Blood. vol. 122, 262-262.

Rouault-Pierre K, Lopez-Onieva L, Foster K, Anjos-Afonso F, Lamrissi-Garcia I, Serrano-Sanchez M, Mitter R, Ivanovic Z et al.(2013). HIF-2α Protects Human Hematopoietic Stem/Progenitors and Acute Myeloid Leukemic Cells from Apoptosis Induced by Endoplasmic Reticulum Stress. Cell Stem Cell vol. 13, (5) 549-563.

Rouault-Pierre K, Lopez-Onieva L, Foster K, Anjos-Afonso F, Lamrissi-Garcia I, Serrano-Sanchez M, Mitter R, Ivanovic Z et al.(2013). HIF-2α Protects Human Hematopoietic Stem/ Progenitors and Acute Myeloid Leukemic Cells from Apoptosis Induced by Endoplasmic Reticulum Stress. Cell Stem Cell

Pizzitola I, Anjos-Afonso F, Rouault-Pierre K, Lassailly F, Tettamanti S, Biondi A, Biagi E, Bonnet D (2013). CHIMERIC ANTIGEN RECEPTOR FOR SPECIFIC TARGETING OF ACUTE MYELOID LEUKAEMIA. PEDIATRIC BLOOD & CANCER. vol. 60, 29-29.

Pizzitola I, Anjos-Afonso F, Rouault-Pierre K, Lassailly F, Biondi A, Biagi E, Bonnet D (2013). Chimeric antigen receptor for specific targeting of acute myeloid leukemia. Cytotherapy. vol. 15,

Pizzitola I, Anjos-Afonso F, Rouault-Pierre K, Lassailly F, Tettamanti S, Biondi A, Biagi E, Bonnet D (2012). Chimeric Antigen Receptor for Specific Targeting of Acute Myeloid Leukemia. Blood. vol. 120, 4225-4225.

Rouault-Pierre K, Lopez-Onieva L, Rezvani H, Anjos-Afonso F, Lamrissi-Garcia I, Vlaski M, De Verneuil H, Ivanovic Z et al. (2012). HYPOXIA-INDUCIBLE FACTOR 1A IS IMPORTANT TO MAINTAIN HUMAN HSC, BUT HIF-2A IS ESSENTIAL TO PROTECT THEM FROM ROS INDUCED APOPTOSIS. EXPERIMENTAL HEMATOLOGY. vol. 40, S102-S103.