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Publications:  Prof Antal Rot

GIRBL T, Lenn T, Perez L, ROLAS L, BARKAWAY A, Thiriot A, del Fresno C, Lynam E et al.(2018). Distinct compartmentalization of the chemokines CXCL1 and CXCL2 and the atypical receptor ACKR1 determine discrete stages of neutrophil diapedesis. Immunity
10.1016/j.immuni.2018.09.018
https://qmro.qmul.ac.uk/xmlui/handle/123456789/50484
Ameti R, Melgrati S, Radice E, Cameroni E, Hub E, Thelen S, Rot A, Thelen M(2018). Characterization of a chimeric chemokine as a specific ligand for ACKR3. Journal of Leukocyte Biology vol. 104, (2) 391-400.
10.1002/JLB.2MA1217-509R
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38943
Rot A, Massberg S, Khandoga AG, von Andrian UH(2018). Chemokines and Hematopoietic Cell Trafficking. Hematology: Basic Principles and Practice,
Duchene J, Novitzky-Basso I, Thiriot A, Casanova-Acebes M, Bianchini M, Etheridge SL, Hub E, Nitz K et al.(2017). Atypical chemokine receptor 1 on nucleated erythroid cells regulates hematopoiesis. Nature Immunology vol. 18, (7) 753-761.
10.1038/ni.3763
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38963
Thiriot A, Perdomo C, Cheng G, Novitzky-Basso I, McArdle S, Kishimoto JK, Barreiro O, Mazo I et al.(2017). Differential DARC/ACKR1 expression distinguishes venular from non-venular endothelial cells in murine tissues. BMC Biology vol. 15, (1)
10.1186/s12915-017-0381-7
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38965
Patten DA, Wilson GK, Bailey D, Shaw RK, Jalkanen S, Salmi M, Rot A, Weston CJ et al.(2017). Human liver sinusoidal endothelial cells promote intracellular crawling of lymphocytes during recruitment: A new step in migration. Hepatology vol. 65, (1) 294-309.
10.1002/hep.28879
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38966
Friess M, Proulx S, Rot A, Halin C (2017). Investigating the Role of ACKR4 on Leukocyte Trafficking Within Lymphatic Vessels and on Lymphatic Vessel Biology. JOURNAL OF VASCULAR RESEARCH. vol. 54, 32-32.
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38983
Cordeiro OG, Chypre M, Brouard N, Rauber S, Alloush F, Romera-Hernandez M, Bénézech C, Li Z et al.(2016). Integrin-alpha IIb identifies murine lymph node lymphatic endothelial cells responsive to RANKL. PLoS ONE vol. 11, (3)
10.1371/journal.pone.0151848
https://qmro.qmul.ac.uk/xmlui/handle/123456789/38967
Alampour-Rajabi S, El Bounkari O, Rot A, Müller-Newen G, Bachelerie F, Gawaz M, Weber C, Schober A et al.(2015). MIF interacts with CXCR7 to promote receptor internalization, ERK1/2 and ZAP-70 signaling, and lymphocyte chemotaxis. FASEB Journal vol. 29, (11) 4497-4511.
10.1096/fj.15-273904
Bachelerie F, Graham GJ, Locati M, Mantovani A, Murphy PM, Nibbs R, Rot A, Sozzani S et al.(2015). An atypical addition to the chemokine receptor nomenclature: IUPHAR Review 15. British Journal of Pharmacology vol. 172, (16) 3945-3949.
10.1111/bph.13182
Lucas B, White AJ, Ulvmar MH, Nibbs RJB, Sitnik KM, Agace WW, Jenkinson WE, Anderson G et al.(2015). CCRL1/ACKR4 is expressed in key thymic microenvironments but is dispensable for T lymphopoiesis at steady state in adult mice. European Journal of Immunology vol. 45, (2) 574-583.
10.1002/eji.201445015
Ward ST, Li KK, Hepburn E, Weston CJ, Curbishley SM, Reynolds GM, Hejmadi RK, Bicknell R et al.(2015). The effects of CCR5 inhibition on regulatory T-cell recruitment to colorectal cancer. British Journal of Cancer vol. 112, (2) 319-328.
10.1038/bjc.2014.572
Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH et al.(2014). International Union of Pharmacology. LXXXIX. Update on the Extended Family of Chemokine Receptors and Introducing a New Nomenclature for Atypical Chemokine Receptors (vol 66, pg 1, 2014). PHARMACOLOGICAL REVIEWS vol. 66, (2) 467-467.
Bachelerie F, Graham GJ, Locati M, Mantovani A, Murphy PM, Nibbs R, Rot A, Sozzani S et al.(2014). New nomenclature for atypical chemokine receptors. Nature Immunology vol. 15, (3) 207-208.
10.1038/ni.2812
Minten C, Alt C, Gentner M, Frei E, Deutsch U, Lyck R, Schaeren-Wiemers N, Rot A et al.(2014). DARC shuttles inflammatory chemokines across the blood-brain barrier during autoimmune central nervous system inflammation. Brain vol. 137, (5) 1454-1469.
10.1093/brain/awu045
Bachelerie F, Ben-Baruch A, Burkhardt AM, Combadiere C, Farber JM, Graham GJ, Horuk R, Sparre-Ulrich AH et al.(2014). International union of pharmacology. LXXXIX. Update on the extended family of chemokine receptors and introducing a new nomenclature for atypical chemokine receptors. Pharmacological Reviews vol. 66, (1) 1-79.
10.1124/pr.113.007724
Ulvmar MH, Werth K, Braun A, Kelay P, Hub E, Eller K, Chan L, Lucas B et al.(2014). The atypical chemokine receptor CCRL1 shapes functional CCL21 gradients in lymph nodes. Nature Immunology vol. 15, (7) 623-630.
10.1038/ni.2889
Baldwin HM, Pallas K, King V, Jamieson T, McKimmie CS, Nibbs RJB, Carballido JM, Jaritz M et al.(2013). Microarray analyses demonstrate the involvement of type 1 interferons in psoriasiform pathology development in D6-Deficient mice. Journal of Biological Chemistry vol. 288, (51) 36473-36483.
10.1074/jbc.M113.491563
Cook SL, George LA, Marshall JL, Zhang Y, Ulvmar MH, Rot A, Toellner K-M (2013). A novel role for the atypical chemoattractant receptor CCRL2 in the B cell antibody response. IMMUNOLOGY. vol. 140, 64-64.
Lucas B, Anderson G, Rot A (2013). Expression and function of atypical chemokine receptor CCRL1 in the thymus. IMMUNOLOGY. vol. 140, 157-157.
Nawaf MG, Ulvmar M, McConnell F, Gaspal F, Yagita H, Allison J, Anderson G, Withers D et al. (2013). Successful CD8 driven anti-tumour immunity: a novel approach?. IMMUNOLOGY. vol. 140, 193-193.
Novitzky-Basso IN, Ulvmar MH, Bacon A, Chaganti S, Moss PAH, Rot A (2013). The Development Of The Humanized Darc Transgenic Mouse. BLOOD. vol. 122,
10.1182/blood.V122.21.2188.2188
Rot A, McKimmie C, Burt CL, Pallas KJ, Jamieson T, Pruenster M, Horuk R, Nibbs RJB et al.(2013). Cell-autonomous regulation of neutrophil migration by the D6 chemokine decoy receptor. Journal of Immunology vol. 190, (12) 6450-6456.
10.4049/jimmunol.1201429
Ward ST, Hepburn E, Li K, Curbishley SM, Hejmadi R, Ismail T, Bicknell R, Rot A et al. (2013). Selective recruitment and retainment of regulatory T cells in human colorectal cancer. LANCET. vol. 381, 113-113.
Whittall C, Kehoe O, King S, Rot A, Patterson A, Middleton J(2013). A chemokine self-presentation mechanism involving formation of endothelial surface microstructures. Journal of Immunology vol. 190, (4) 1725-1736.
10.4049/jimmunol.1200867
Ward ST, Hepburn EA, Li K-K, Curbishley SM, Hejmadi RK, Ismail T, Bicknell R, Rot A et al. (2013). The selective recruitment and retainment of regulatory T cells in human colorectal cancer. CANCER RESEARCH. vol. 73,
10.1158/1538-7445.TUMIMM2012-A73
Novitzky-Basso I, Rot A(2012). Duffy antigen receptor for chemokines and its involvement in patterning and control of inflammatory chemokines. Frontiers in Immunology vol. 3, (AUG)
10.3389/fimmu.2012.00266
Serre K, Cunningham AF, Coughlan RE, Lino AC, Rot A, Hub E, Moser K, Manz R et al.(2012). CD8 T cells induce T-bet-dependent migration toward CXCR3 ligands by differentiated B cells produced during responses to alum-protein vaccines. Blood vol. 120, (23) 4552-4559.
10.1182/blood-2012-03-417733
Singh MD, King V, Baldwin H, Burden D, Thorrat A, Holmes S, McInnes IB, Nicoll R et al.(2012). Elevated expression of the chemokine-scavenging receptor D6 is associated with impaired lesion development in psoriasis. American Journal of Pathology vol. 181, (4) 1158-1164.
10.1016/j.ajpath.2012.06.042
Graham GJ, Locati M, Mantovani A, Rot A, Thelen M(2012). The biochemistry and biology of the atypical chemokine receptors. Immunology Letters vol. 145, (1-2) 30-38.
10.1016/j.imlet.2012.04.004
Novitzky-Basso IN, Ulvmar MH, Bacon A, Moss PAH, Rot A (2012). The development of humanized DARC FYB(ES) transgenic mouse. BRITISH JOURNAL OF HAEMATOLOGY. vol. 157, 20-20.
Sallmann E, Reininger B, Brandt S, Duschek N, Hoflehner E, Garner-Spitzer E, Platzer B, Dehlink E et al.(2011). High-affinity IgE receptors on dendritic cells exacerbate Th2-dependent inflammation. Journal of Immunology vol. 187, (1) 164-171.
10.4049/jimmunol.1003392
Ulvmar MH, Hub E, Rot A(2011). Atypical chemokine receptors. Experimental Cell Research vol. 317, (5) 556-568.
10.1016/j.yexcr.2011.01.012
Thiriot A, Perdomo C, Omid S, Puyraimond-Zemmour D, Rot A, Siu J, von Andrian U (2011). Understanding the role of segmental specialization of venular endothelial cells in the regulation of lymphocyte trafficking. JOURNAL OF VASCULAR RESEARCH. vol. 48, 252-252.
Cowan J, Desanti G, Jenkinson W, White A, Rot A, Lane P, Jenkinson E, Anderson G (2010). Dynamic changes in chemokine receptor expression reveals multiple checkpoints in the intrathymic positive selection of CD4(+) T-cells. IMMUNOLOGY. vol. 131, 157-157.
Madigan J, Freeman DJ, Menzies F, Forrow S, Nelson SM, Young A, Sharkey A, Moffett A et al.(2010). Chemokine scavenger D6 is expressed by trophoblasts and aids the survival of mouse embryos transferred into allogeneic recipients. Journal of Immunology vol. 184, (6) 3202-3212.
10.4049/jimmunol.0902118
Naumann U, Cameroni E, Pruenster M, Mahabaleshwar H, Raz E, Zerwes HG, Rot A, Thelen M(2010). CXCR7 functions as a scavenger for CXCL12 and CXCL11. PLoS ONE vol. 5, (2)
10.1371/journal.pone.0009175
Eller K, Weber T, Pruenster M, Wolf AM, Mayer G, Rosenkranz AR, Rot A(2010). CCR7 deficiency exacerbates injury in acute nephritis due to aberrant localization of regulatory T cells. Journal of the American Society of Nephrology vol. 21, (1) 42-52.
10.1681/ASN.2009020133
Rot A(2010). Chemokine patterning by glycosaminoglycans and interceptors. Frontiers in Bioscience vol. 15, (2) 645-660.
10.2741/3638
McKimmie CS, Fraser AR, Hansell C, Gutiérrez L, Philipsen S, Connell L, Rot A, Kurowska-Stolarska M et al.(2009). Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1 (Journal of Immunology (2008) 181, (3353-3363)). Journal of Immunology vol. 181, (11) 8170-8181.
Rot A, Horuk R(2009). Chapter 9 The Duffy Antigen Receptor for Chemokines. Methods in Enzymology vol. 461, (B) 191-206.
10.1016/S0076-6879(09)05409-3
Pruenster M, Dimitrova S, Middleton J, Richmond A, Graham GJ, Segerer S, Nibbs RJB, Rot A (2009). Duffy antigen/receptor for chemokines transports chemokines and supports their pro-migratory activity 'in vitro' and 'in vivo'. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. vol. 39, 23-24.
Széles L, Keresztes G, Töröcsik D, Balajthy Z, Krenács L, Póliska S, Steinmeyer A, Zuegel U et al.(2009). 1,25-Dihydroxyvitamin D<inf>3</inf> Is an autonomous regulator of the transcriptional changes leading to a tolerogenic dendritic cell phenotype. Journal of Immunology vol. 182, (4) 2074-2083.
10.4049/jimmunol.0803345
Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M, Middleton J, Richmond A, Graham GJ et al.(2009). Erratum: The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity (Nature Immunology (2009) vol. 10 (101-108)). Nature Immunology vol. 10, (2)
10.1038/ni0209-223d
Vielhauer V, Allam R, Lindenmeyer MT, Cohen CD, Draganovici D, Mandelbaum J, Eltrich N, Nelson PJ et al.(2009). Efficient renal recruitment of macrophages and T cells in mice lacking the duffy antigen/receptor for chemokines. American Journal of Pathology vol. 175, (1) 119-131.
10.2353/ajpath.2009.080590
Pruenster M, Mudde L, Bombosi P, Dimitrova S, Zsak M, Middleton J, Richmond A, Graham GJ et al.(2009). The Duffy antigen receptor for chemokines transports chemokines and supports their promigratory activity. Nature Immunology vol. 10, (1) 101-108.
10.1038/ni.1675
McKimmie CS, Fraser AR, Hansell C, Gutierrez L, Philipsen S, Connell L, Rot A, Kurowska-Stolarska M et al.(2008). Hemopoietic Cell Expression of the Chemokine Decoy Receptor D6 Is Dynamic and Regulated by GATA1 (vol 181, pg 3353, 2008). JOURNAL OF IMMUNOLOGY vol. 181, (11) 8170-8181.
10.4049/jimmunol.181.11.8170-a
Rubic T, Lametschwandtner G, Jost S, Hinteregger S, Kund J, Carballido-Perrig N, Schwärzler C, Junt T et al.(2008). Triggering the succinate receptor GPR91 on dendritic cells enhances immunity. Nature Immunology vol. 9, (11) 1261-1269.
10.1038/ni.1657
McKimmie CS, Fraser AR, Hansell C, Gutiérrez L, Philipsen S, Connell L, Rot A, Kurowska-Stolarska M et al.(2008). Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. Journal of Immunology vol. 181, (5) 3353-3363.
10.4049/jimmunol.181.5.3353
Chamberlain G, Wright K, Rot A, Ashton B, Middleton J(2008). Murine mesenchymal stem cells exhibit a restricted repertoire of functional chemokine receptors: Comparison with human. PLoS ONE vol. 3, (8)
10.1371/journal.pone.0002934
Hochegger K, Rosenkranz A, Rot A (2008). CCR7 is essential for regulatory T cell function in anti-GBM glomerulonephritis. WIENER KLINISCHE WOCHENSCHRIFT. vol. 120, 51-51.
Förster R, Davalos-Misslitz AC, Rot A(2008). CCR7 and its ligands: Balancing immunity and tolerance. Nature Reviews Immunology vol. 8, (5) 362-371.
10.1038/nri2297
Chamberlain G, Rot A, Ashton B, Middleton J (2008). Chemokine receptors on human and murine mesenchymal stem cells. RHEUMATOLOGY. vol. 47, II61-II62.
McKimmie CS, Fraser AR, Hansell C, Gutiérrez L, Philipsen S, Connell L, Rot A, Kurowska-Stolarska M et al.(2008). Hemopoietic cell expression of the chemokine decoy receptor D6 is dynamic and regulated by GATA1. Journal of immunology (Baltimore, Md. : 1950) vol. 181, (11) 8171-8181.
10.4049/jimmunol.181.11.8170-a
Koehn J, Huesken D, Jaritz M, Rot A, Zurini M, Dwertmann A, Beutler B, Korthäuer U(2007). Assessing the function of human UNC-93B in Toll-like receptor signaling and major histocompatibility complex II response. Human Immunology vol. 68, (11) 871-878.
10.1016/j.humimm.2007.07.007
Winter D, Moser J, Kriehuber E, Wiesner C, Knobler R, Trautinger F, Bombosi P, Stingl G et al.(2007). Down-modulation of CXCR3 surface expression and function in CD8<sup>+</sup> T cells from cutaneous T cell lymphoma patients. Journal of Immunology vol. 179, (6) 4272-4282.
10.4049/jimmunol.179.6.4272
Colditz IG, Schneider MA, Pruenster M, Rot A(2007). Chemokines at large: In-vivo mechanisms of their transport, presentation and clearance. Thrombosis and Haemostasis vol. 97, (5) 688-693.
10.1160/TH07-02-0105
Schneider MA, Meingassner JG, Lipp M, Moore HD, Rot A(2007). CCR7 is required for the in vivo function of CD4<sup>+</sup> CD25 <sup>+</sup> regulatory T cells. Journal of Experimental Medicine vol. 204, (4) 735-745.
10.1084/jem.20061405
Pruenster M, Rot A(2006). Throwing light on DARC. Biochemical Society Transactions vol. 34, (6) 1005-1008.
10.1042/BST0341005
Biedermann T, Lametschwandtner G, Tangemann K, Kund J, Hinteregger S, Carballido-Perrig N, Rot A, Schwärzler C et al.(2006). IL-12 instructs skin homing of human Th2 cells. Journal of Immunology vol. 177, (6) 3763-3770.
10.4049/jimmunol.177.6.3763
Haraldsen G, Rot A(2006). Coy decoy with a new ploy: Interceptor controls the levels of homeostatic chemokines. European Journal of Immunology vol. 36, (7) 1659-1661.
10.1002/eji.200636327
Floess S, Rot A(2006). Chemokines Drive Inflammatory Leukocyte Recruitment. Leukocyte Trafficking: Molecular Mechanisms, Therapeutic Targets, and Methods,
Jamieson T, Cook DN, Nibbs RJB, Rot A, Nixon C, Mclean P, Alcami A, Lira SA et al.(2005). The chemokine receptor D6 limits the inflammatory response in vivo. Nature Immunology vol. 6, (4) 403-411.
10.1038/ni1182
Rot A(2005). Contribution of Duffy antigen to chemokine function. Cytokine and Growth Factor Reviews vol. 16, (6) 687-694.
10.1016/j.cytogfr.2005.05.011
Dar A, Goichberg P, Shinder V, Kalinkovich A, Kollet O, Netzer N, Margalit R, Zsak M et al.(2005). Chemokine receptor CXCR4-dependent internalization and resecretion of functional chemokine SDF-1 by bone marrow endothelial and stromal cells. Nature Immunology vol. 6, (10) 1038-1046.
10.1038/ni1251
Dar A, Kollet O, Shinder V, Goichberg P, Kalinkovich A, Zsak M, Rot A, Lapidot T (2005). CXCR4-dependent internalization and secretion of functional SDF-1 by bone marrow endothelial and stromal cells. EXPERIMENTAL HEMATOLOGY. vol. 33, 118-118.
Meindl S, Rot A, Hoetzenecker W, Kato S, Cross HS, Elbe-Bürger A(2005). Vitamin D receptor ablation alters skin architecture and homeostasis of dendritic epidermal T cells. British Journal of Dermatology vol. 152, (2) 231-241.
10.1111/j.1365-2133.2005.06392.x
Kohrgruber N, Gröger M, Meraner P, Kriehuber E, Petzelbauer P, Brandt S, Stingl G, Rot A et al.(2004). Plasmacytoid dendritic cell recruitment by immobilized CXCR3 ligands. Journal of Immunology vol. 173, (11) 6592-6602.
10.4049/jimmunol.173.11.6592
McKeever U, Baier K, Pecanka R, Kowalsky E, Rot A (2004). Pimecrolimus ameliorates disease in a prophylactic mouse model of lupus. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 123,
Rot A, Von Andrian UH(2004). Chemokines in innate and adaptive host defense: Basic chemokinese grammar for immune cells. Annual Review of Immunology vol. 22, 891-928.
10.1146/annurev.immunol.22.012703.104543
Weber M, Blair E, Simpson CV, O'Hara M, Blackburn PE, Rot A, Graham GJ, Nibbs RJB(2004). The Chemokine Receptor D6 Constitutively Traffics to and from the Cell Surface to Internalize and Degrade Chemokines. Molecular Biology of the Cell vol. 15, (5) 2492-2508.
10.1091/mbc.E03-09-0634
McKeever U, Baier K, Rot A (2004). Beneficial effects of Pimecrolimus in the Mrl/lpr mouse lupus model. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 122, A5-A5.
Gruber R, Karreth F, Kandler B, Fuerst G, Rot A, Fischer MB, Watzek G(2004). Platelet-released supernatants increase migration and proliferation, and decrease osteogenic differentiation of bone marrow-derived mesenchymal progenitor cells under in vitro conditions. Platelets vol. 15, (1) 29-35.
10.1080/09537100310001643999
Zemann B, Rot A(2003). What dogs may teach humans about the vertical transmission of allergy predisposition. Immunology vol. 110, (4) 427-429.
10.1111/j.1365-2567.2003.01778.x
Gruber R, Karreth F, Kandler B, Rot A, Fischer M, Furst G, Watzek G (2003). Platelet-released supernatants are mitogenic and chemoattractant for mesenchymal progenitor cells - involvement of PDGF and mitogen-activated protein kinase signaling. BONE. vol. 33, S16-S17.
Rot A(2003). In situ binding assay for studying chemokine interactions with endothelial cells. Journal of Immunological Methods vol. 273, (1-2) 63-71.
10.1016/S0022-1759(02)00502-1
Bacon K, Baggiolini M, Broxmeyer H, Horuk R, Lindley I, Mantovani A, Matsushima K, Murphy P et al.(2003). Chemokine/chemokine receptor nomenclature. Cytokine vol. 21, (1) 48-49.
10.1016/S1043-4666(02)00493-3
Nibbs R, Graham G, Rot A(2003). Chemokines on the move: Control by the chemokine "interceptors" Duffy blood group antigen and D6. Seminars in Immunology vol. 15, (5) 287-294.
10.1016/j.smim.2003.08.006
Biedermann T, Schwärzler C, Lametschwandtner G, Thoma G, Carballido-Perrig N, Kund J, de Vries JE, Rot A et al.(2002). Targeting CLA/E-selectin interactions prevents CCR4-mediated recruitment of human Th2 memory cells to human skin in vivo. European Journal of Immunology vol. 32, (11) 3171-3180.
10.1002/1521-4141(200211)32:11<3171::AID-IMMU3171>3.0.CO;2-4
Biedermann T, Schwärzler C, Lametschwandtner G, Thoma G, Carballido-Perrig N, Kund J, de Vries JE, Rot A et al.(2002). Targeting CLA/E-selectin interactions prevents CCR4-mediated recruitment of human Th2 memory cells to human skin in vivo. Eur J Immunol vol. 32, (11) 3171-3180.
10.1002/1521-4141(200211)32:11<3171::AID-IMMU3171>3.0.CO;2-4
IUIS/WHO Subcommittee on Chemokine Nomenclature(2002). Chemokine/chemokine receptor nomenclature. J Immunol Methods vol. 262, (1-2) 1-3.
10.1016/s0022-1759(02)00042-x
Bacon K, Baggiolini M, Broxmeyer H, Horuk R, Lindley I, Mantovani A, Matsushima K, Murphy P et al.(2002). Chemokine/chemokine receptor nomenclature. Journal of Interferon and Cytokine Research vol. 22, (10) 1067-1068.
10.1089/107999002760624305
Elbe-Bürger A, Egyed A, Olt S, Klubal R, Mann U, Rappersberger K, Rot A, Stingl G(2002). Overexpression of IL-4 alters the homeostasis in the skin. Journal of Investigative Dermatology vol. 118, (5) 767-778.
10.1046/j.1523-1747.2002.01753.x
Bednar-Tantscher E, Mudde GC, Rot A(2001). Maternal antigen stimulation downregulates via mother's milk the specific immune responses in young mice. International Archives of Allergy and Immunology vol. 126, (4) 300-308.
10.1159/000049527
Palframan RT, Jung S, Cheng G, Weninger W, Luo Y, Dorf M, Littman DR, Rollins BJ et al.(2001). Inflammatory chemokine transport and presentation in HEV: A remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues. Journal of Experimental Medicine vol. 194, (9) 1361-1373.
10.1084/jem.194.9.1361
Palframan RT, Jung S, Cheng G, Weninger W, Luo Y, Dorf M, Littman DR, Rollins BJ et al. (2001). Inflammatory chemokine transport and presentation in HEV: A remote control mechanism for monocyte recruitment to lymph nodes in inflamed tissues. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 117, 1003-1003.
Jilma-Stohlawetz P, Homoncik M, Drucker C, Marsik C, Rot A, Mayr WR, Seibold B, Jilma B(2001). Fy phenotype and gender determine plasma levels of monocyte chemotactic protein. Transfusion vol. 41, (3) 378-381.
10.1046/j.1537-2995.2001.41030378.x
Nibbs RJ, Kriehuber E, Ponath PD, Parent D, Qin S, Campbell JD, Henderson A, Kerjaschki D et al.(2001). The beta-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. Am J Pathol vol. 158, (3) 867-877.
10.1016/s0002-9440(10)64035-7
Kopp T, Kieffer JD, Rot A, Strommer S, Stingl G, Kupper TS(2001). Inflammatory skin disease in K14/p40 transgenic mice: Evidence for interleukin-12-like activities of p40. Journal of Investigative Dermatology vol. 117, (3) 618-626.
10.1046/j.1523-1747.2001.01441.x
Hoffmann R, Rot A, Niiyama S, Billich A(2001). Steroid sulfatase in the human hair follicle concentrates in the dermal papilla. Journal of Investigative Dermatology vol. 117, (6) 1342-1348.
10.1046/j.0022-202x.2001.01547.x
Nibbs RJB, Kriehuber E, Ponath PD, Parent D, Qin S, Campbell JDM, Henderson A, Kerjaschki D et al.(2001). The β-chemokine receptor D6 is expressed by lymphatic endothelium and a subset of vascular tumors. American Journal of Pathology vol. 158, (3) 867-877.
10.1016/S0002-9440(10)64035-7
Dawson TC, Lentsch AB, Wang Z, Cowhig JE, Rot A, Maeda N, Peiper SC(2000). Exaggerated response to endotoxin in mice lacking the Duffy antigen/receptor for chemokines (DARC). Blood vol. 96, (5) 1681-1684.
10.1182/blood.V96.5.1681.h8001681a_1681_1684
Rot A, Schwarzinger E, Szakáll S, Radics T, Vályi-Nagy I, Kiss C, Márton IJ(2000). Differential in situ distribution of interleukin-8, monocyte chemoattractant protein-1 and Rantes in human chronic periapical granuloma. Oral Microbiology and Immunology vol. 15, (1) 63-65.
10.1034/j.1399-302X.2000.150111.x
Stein JV, Rot A, Luo Y, Narasimhaswamy M, Nakano H, Gunn MD, Matsuzawa A, Quackenbush EJ et al.(2000). The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function- associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial venules. Journal of Experimental Medicine vol. 191, (1) 61-75.
10.1084/jem.191.1.61
Charbonnier AS, Rot A, Kohrgruber N, Kriehuber E, Stingl G, Maurer D (2000). MIP-3 alpha is involved in the constitutive trafficking of epidermal Langerhans cells. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 114, 226-226.
Charbonnier AS, Kohrgruber N, Kriehuber E, Stingl G, Rot A, Maurer D(1999). Macrophage inflammatory protein 3α is involved in the constitutive trafficking of epidermal langerhans cells. Journal of Experimental Medicine vol. 190, (12) 1755-1767.
10.1084/jem.190.12.1755
Dawson TC, Maeda N, Wang ZX, Rot A, Peiper SC (1999). Evaluation of the pathophysiological role of the Duffy blood group antigen: Generation and characterization of DARC deficient mice. BLOOD. vol. 94, 369A-369A.
Charbonnier AS, Rot A, Kohrgruber N, Kriehuber E, Stingl G, Maurer D (1999). MIP-3 alpha is involved in the constitutive trafficking of epidermal Langerhans cells. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 113, 431-431.
Charbonnier A, Rot A, Stingl G, Maurer D (1999). The chemokine receptor expression profile and chemokine responsiveness of human dendritic cells is dependent on cell subtype and maturational stage. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 112, 627-627.
Wolff B, Burns AR, Middleton J, Rot A(1998). Endothelial cell 'memory' of inflammatory stimulation: Human venular endothelial cells store interleukin 8 in Weibel-Palade bodies. Journal of Experimental Medicine vol. 188, (9) 1757-1762.
10.1084/jem.188.9.1757
Michie CA, Tantscher E, Schall T, Rot A(1998). Physiological secretion of chemokines in human breast milk. European Cytokine Network vol. 9, (2) 123-129.
Lam C, Chujor CSN, Schwarzinger E, Morhenn VB, Rot A (1998). Co-localization of inducible nitric oxide synthase and nitration of tyrosine residues in psoriatic skin. JOURNAL OF INVESTIGATIVE DERMATOLOGY. vol. 110, 634-634.
Hub E, Rot A(1998). Binding of RANTES, MCP-1, MCP-3, and MIP-1α to cells in human skin. American Journal of Pathology vol. 152, (3) 749-757.
Horcher M, Rot A, Aschauer H, Besemer J(1998). IL-8 derivatives with a reduced potential to form homodimers are fully active in vitro and in vivo. Cytokine vol. 10, (1) 1-12.
10.1006/cyto.1997.0251
Charbonnier AS, Rot A, Stingl G, Maurer D (1998). The chemokine receptor expression profile and chemokine responsiveness of human dendritic cells is dependent on cell subtype and maturational stage. JOURNAL OF LEUKOCYTE BIOLOGY. 76-76.
Michie CA, Tantscher E, Rot A(1998). The long term effects of breastfeeding: A role for the cells in breast milk?. Journal of Tropical Pediatrics vol. 44, (1) 2-3.
10.1093/tropej/44.1.2
Middleton J, Neil S, Wintle J, Clark-Lewis I, Moore H, Lam C, Auer M, Hub E et al.(1997). Transcytosis and surface presentation of IL-8 by venular endothelial cells. Cell vol. 91, (3) 385-395.
10.1016/s0092-8674(00)80422-5
Billich A, Winkler G, Aschauer H, Rot A, Peichl P(1997). Presence of cyclophilin A in synovial fluids of patients with rheumatoid arthritis. Journal of Experimental Medicine vol. 185, (5) 975-980.
10.1084/jem.185.5.975
Middlelon J, Wintle J, Rot A(1996). Mechanism of chemokine presentation to leucocytes. Skin Pharmacology vol. 9, (2)
Hub E, Rot A(1996). Methods for Study of Chemokine Receptors in the Tissues. Methods vol. 10, (1) 119-125.
10.1006/meth.1996.0085
Michie CA, Rot A, Fisher C (1996). Do chemokines cause mastitis?. PEDIATRIC RESEARCH. vol. 39, 60-60.
Rot A(1996). In flammatory and physiological roles of chemokines. Pathology &amp; Oncology Research vol. 2, (1-2) 16-20.
10.1007/BF02893942
Rot A, Hub E, Middleton J, Pons F, Rabeck C, Thierer K, Wintle J, Wolff B et al.(1996). Some aspects of IL-8 pathophysiology III: Chemokine interaction with endothelial cells. Journal of Leukocyte Biology vol. 59, (1) 39-44.
10.1002/jlb.59.1.39
Kukielka GL, Smith CW, LaRosa GJ, Manning AM, Mendoza LH, Daly TJ, Hughes BJ, Youker KA et al.(1995). Interleukin-8 gene induction in the myocardium after ischemia and reperfusion in vivo. Journal of Clinical Investigation vol. 95, (1) 89-103.
10.1172/JCI117680
Jones AP, Webb LMC, Anderson AO, Leonard EJ, Rot A(1995). Normal human sweat contains interleukin-8. Journal of Leukocyte Biology vol. 57, (3) 434-437.
10.1002/jlb.57.3.434
Rot A, ZaksRot I, EUROPE R (1995). Radcure in Russia. RADTECH EUROPE 95 - CONFERENCE PROCEEDINGS. 313-320.
MICHIE CA, WEBB L, ROT A, HARVEY D (1994). THE PHYSIOLOGICAL SECRETION OF AN INFLAMMATORY CYTOKINE IN INFANT TEARS. PEDIATRIC RESEARCH. vol. 35, A188-A188.
MICHIE CA, SOO KS, SCHALL T, ROT A, HARVEY D (1994). A MECHANISM FOR MATERNAL MODIFICATION OF INFANT IMMUNITY. PEDIATRIC RESEARCH. vol. 35, 259-259.
10.1203/00006450-199402000-00029
Karakurum M, Shreeniwas R, Chen J, Pinsky D, Yan SD, Anderson M, Sunouchi K, Major J et al.(1994). Hypoxic induction of interleukin-8 gene expression in human endothelial cells. Journal of Clinical Investigation vol. 93, (4) 1564-1570.
10.1172/JCI117135
Auer M, Owens SR, Pfeffer S, Kallen J, Wasserbauer E, Aschauer H, Ehn G, Rot A et al.(1993). Elucidation of structure function relationships in the IL-8 family by X- ray crystallography. Advances in Experimental Medicine and Biology vol. 351, 171-182.
10.1007/978-1-4615-2952-1_18
Rot A, Jones AP, Webb LMC(1993). Some aspects of NAP-1/IL-8 pathophysiology II: Chemokine secretion by exocrine glands. Advances in Experimental Medicine and Biology vol. 351, 77-85.
10.1007/978-1-4615-2952-1_9
ROT A (1993). ENDOTHELIAL-CELL BINDING OF NAP-1/IL-8 - ROLE IN NEUTROPHIL EMIGRATION. JOURNAL OF CELLULAR BIOCHEMISTRY. 352-352.
Webb LMC, Ehrengruber MU, Clark-Lewis I, Baggiolini M, Rot A(1993). Binding to heparan sulfate or heparin enhances neutrophil responses to interleukin 8. Proceedings of the National Academy of Sciences of the United States of America vol. 90, (15) 7158-7162.
10.1073/pnas.90.15.7158
Zwahlen R, Walz A, Rot A(1993). In Vitro and in Vivo Activity and Pathophysiology of Human Interleukin-8 and Related Peptides. vol. 34, (PB) 27-42.
10.1016/B978-0-12-364935-5.50008-0
Rot A(1993). Neutrophil attractant/activation protein‐1 (interleukin‐8) induces in vitro neutrophil migration by haptotactic mechanism. European Journal of Immunology vol. 23, (1) 303-306.
10.1002/eji.1830230150
Bischoff SC, Krieger M, Brunner T, Rot A, Tscharner VV, Marco Baggiolini, Dahinden CA(1993). RANTES and related chemokines activate human basophil granulocytes through different G protein‐coupled receptors. European Journal of Immunology vol. 23, (3) 761-767.
10.1002/eji.1830230329
Rot A, Krieger M, Brunner T, Bischoff SC, Schall TJ, Dahinden CA(1992). RANTES and macrophage inflammatory protein lot induce the migration and activation of normal human eosinophil granulocytes. Journal of Experimental Medicine vol. 176, (6) 1489-1495.
10.1084/jem.176.6.1489
Rot A(1992). Binding of neutrophil attractant/activation protein-1 (interleukin 8) to resident dermal cells. Cytokine vol. 4, (5) 347-352.
10.1016/1043-4666(92)90077-5
FOSTER CA, MANDAK B, KROMER E, ROT A(1992). Calcitonin Gene‐Related Peptide is Chemotactic for Human T Lymphocytes. Annals of the New York Academy of Sciences vol. 657, (1) 397-404.
10.1111/j.1749-6632.1992.tb22785.x
Rot A(1992). Endothelial cell binding of NAP-1/IL-8: role in neutrophil emigration. Immunology Today vol. 13, (8) 291-294.
10.1016/0167-5699(92)90039-A
Samonigg H, Wilders-Truschnig M, Loibner H, Plot R, Rot A, Kuss I, Werner G, Stöger H et al.(1992). Immune response to tumor antigens in a patient with colorectal cancer after immunization with anti-idiotype antibody. Clinical Immunology and Immunopathology vol. 65, (3) 271-277.
10.1016/0090-1229(92)90157-J
FOSTER CA, MANDAK B, KROMER E, ROT A (1991). THE NEUROPEPTIDE SUBSTANCE-P IS CHEMOTACTIC FOR HUMAN T-CELLS. CLINICAL RESEARCH. vol. 39, A535-A535.
Leonard EJ, Yoshimura T, Rot A, Noer K, Walz A, Baggiolini M, Walz DA, Goetzl EJ et al.(1991). Chemotactic activity and receptor binding of neutrophil attractant/activation protein-1 (NAP-1) and structurally related host defense cytokines: Interaction of NAP-2 with the NAP-1 receptor. Journal of Leukocyte Biology vol. 49, (3) 258-265.
10.1002/jlb.49.3.258
Rot A(1991). Chemotactic potency of recombinant human neutrophil attractant/activation protein-1 (interleukin-8) for polymorphonuclear leukocytes of different species. Cytokine vol. 3, (1) 21-27.
10.1016/1043-4666(91)90006-Y
Zalatnai A, Sárosi I, Rot A, Lapsis K(1991). Inhibitory and promoting effects of carbon tetrachloride-induced liver cirrhosis on the diethylnitrosamine hepatocarcinogenesis in rats. Cancer Letters vol. 57, (1) 67-73.
10.1016/0304-3835(91)90065-P
Rot A(1991). Some aspects of NAP-1 pathophysiology: Lung damage caused by a blood-borne cytokine. Advances in Experimental Medicine and Biology vol. 305, 127-136.
10.1007/978-1-4684-6009-4_15
Loibner H, Plot R, Rot A, Werner G, Wrann M, Samonigg H, Schmid M, Stöger H et al.(1990). Immunoreactivity of patient with colorectal cancer metastasis after immunisation with anti-idiotypes. The Lancet vol. 335, (8682)
10.1016/0140-6736(90)90044-6
LINDLEY IJD, ASCHAUER H, LAM C, BESEMER J, ROT A (1990). INVITRO AND INVIVO ACTIVITY OF MUTAGENIZED VERSIONS OF RECOMBINANT HUMAN NAP-1/IL-8 AND IDENTIFICATION OF FUNCTIONALLY IMPORTANT DOMAINS. MOLECULAR AND CELLULAR BIOLOGY OF CYTOKINES. vol. 10, 345-350.
Paku S, Rot A, Ladányi A, Lapis K(1989). Demonstration of the organ preference of liver selected 'high metastatic' Lewis lung tumor cell line. Clinical &amp; Experimental Metastasis vol. 7, (6) 599-607.
10.1007/BF01753671
Rot A, Henderson LE, Sowder R, Leonard EJ(1989). Staphylococcus aureus tetrapeptide with high chemotactic potency and efficacy for human leukocytes. Journal of Leukocyte Biology vol. 45, (2) 114-120.
10.1002/jlb.45.2.114
ROT A, HENDERSON LE, COPELAND TD, LEONARD EJ (1987). A NEW SERIES OF LIGANDS FOR THE HUMAN FORMYL PEPTIDE RECEPTOR - TETRAPEPTIDES WITH HIGH CHEMOTACTIC POTENCY AND EFFICACY. JOURNAL OF LEUKOCYTE BIOLOGY. vol. 42, 387-387.
Rot A, Henderson LE, Copeland TD, Leonard EJ(1987). A series of six ligands for the human formyl peptide receptor: Tetrapeptides with high chemotactic potency and efficacy. Proceedings of the National Academy of Sciences of the United States of America vol. 84, (22) 7967-7971.
10.1073/pnas.84.22.7967
YOSHIMURA T, ROT A, LEONARD EJ (1986). CHEMOTACTIC EFFICACY - OXIDATION OF STIMULUS BY RESPONDING CELLS. JOURNAL OF LEUKOCYTE BIOLOGY. vol. 40, 280-281.
Yoshimura T, Rot A, Leonard EJ(1986). Chemoattractant efficacy: Oxidation of stimulus by responding cells. Biochemical and Biophysical Research Communications vol. 138, (1) 66-71.
10.1016/0006-291X(86)90247-0
Rot A, Henderson LE, Leonard EJ(1986). Staphylococcus aureus-derived chemoattractant activity for human monocytes. Journal of Leukocyte Biology vol. 40, (1) 43-53.
10.1002/jlb.40.1.43
Takacs L, Szende B, Rot A, Diamanstein T(1985). Expression of MHC class II antigens on bile duct epithelium in experimental graft versus host disease. Clinical and Experimental Immunology vol. 60, (3) 449-456.
ROT A, HENDERSON LE, LEONARD EJ (1984). CHEMOATTRACTANT ACTIVITY FOR HUMAN-MONOCYTES DERIVED FROM STAPHYLOCOCCUS-AUREUS CULTURE FILTRATES. JOURNAL OF LEUKOCYTE BIOLOGY. vol. 36, 390-391.
Takacs L, Szende B, Monostori E, Rot A, Lapis K, Szecseny A, Ando I(1983). EXPRESSION OF HLA-DR ANTIGENS ON BILEDUCT CELLS OF REJECTED LIVER TRANSPLANT. The Lancet vol. 322, (8365-8366)
10.1016/S0140-6736(83)90845-0
TAKACS L, SZENDE B, MONOSTORI E, ROT A, LAPIS K, SZECSENY A, ANDO I(1983). EXPRESSION OF HLA-DR ANTIGENS ON BILEDUCT CELLS OF REJECTED LIVER-TRANSPLANT. LANCET vol. 2, (8365) 1500-1500.
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