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Publications:  Prof Rob Krams

Krams IA, Luoto S, Krama T, Krams R, Sieving K, Trakimas G, Elferts D, Rantala MJ et al.(2020). Egalitarian mixed-species bird groups enhance winter survival of subordinate group members but only in high-quality forests. Scientific Reports vol. 10, (1)
10.1038/s41598-020-60144-w
Bourantas CV, Zanchin T, Torii R, Serruys PW, Karagiannis A, Ramasamy A, Safi H, Coskun AU et al.(2020). Shear Stress Estimated by Quantitative Coronary Angiography Predicts Plaques Prone to Progress and Cause Events. JACC: Cardiovascular Imaging
10.1016/j.jcmg.2020.02.028
Evans RJ, Lavin B, Phinikaridou A, Chooi KY, Mohri Z, Wong E, Boyle JJ, Krams R et al.(2020). Targeted Molecular Iron Oxide Contrast Agents for Imaging Atherosclerotic Plaque. Nanotheranostics vol. 4, (4) 184-194.
10.7150/ntno.44712
Gijsen F, Katagiri Y, Barlis P, Bourantas C, Collet C, Coskun U, Daemen J, Dijkstra J et al.(2019). Expert recommendations on the assessment of wall shear stress in human coronary arteries: existing methodologies, technical considerations, and clinical applications. European Heart Journal
10.1093/eurheartj/ehz551
https://qmro.qmul.ac.uk/xmlui/handle/123456789/60081
Baumbach A(2019). Reliable in Vivo Intravascular Imaging Plaque Characterisation: A Challenge Unmet. American Heart Journal
10.1016/j.ahj.2019.07.008
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59756
Mohri Z, Del Rio Hernandez A, Krams R(2019). The emerging role of YAP/TAZ in mechanotransduction. J Thorac Dis vol. 9, (5) E507-E509.
10.21037/jtd.2017.03.179
Baeriswyl DC, Prionisti I, Peach T, Tsolkas G, Chooi KY, Vardakis J, Morel S, Diagbouga MR et al.(2019). Disturbed flow induces a sustained, stochastic NF-κB activation which may support intracranial aneurysm growth in vivo. Sci Rep vol. 9, (1) 4738-4738.
10.1038/s41598-019-40959-y
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58202
Poulsen CB, Pedrigi RM, Pareek N, Kilic ID, Holm NR, Bentzon JF, Bøtker HE, Falk E et al.(2019). Plaque burden influences accurate classification of fibrous cap atheroma by in vivo optical coherence tomography in a porcine model of advanced coronary atherosclerosis. EuroIntervention vol. 14, (10) 1129-1135.
10.4244/EIJ-D-17-01028
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58296
Evans RJ, Hernandez-Gil J, Mohri Z, Chooi KY, Lavin-Plaza B, Phinikaridou A, Pease JE, Krams R et al. (2018). DEVELOPING NEW TARGETED MOLECULAR CONTRAST AGENTS FOR IMAGING INFLAMMATION OF VULNERABLE PLAQUES. CARDIOVASCULAR RESEARCH. vol. 114, S3-S4.
10.1093/cvr/cvy216.014
Yang P, Silva R, Pedrigi R, Patel M, Chooi Y, Ahmed R, Naser J, Krams R (2018). FLUID-STRUCTURE INTERACTION MODELLING FOR ANALYSING ADVANCED CORONARY ATHEROSCLEROTIC PLAQUE FORMATION IN TRANSGENIC HYPERLIPIDAEMIC MINIPIGS. CARDIOVASCULAR RESEARCH. vol. 114, S10-S10.
10.1093/cvr/cvy216.037
Abuammah A, Maimari N, Towhidi L, Frueh J, Chooi KY, Warboys C, Krams R(2018). New developments in mechanotransduction: Cross talk of the Wnt, TGF-β and Notch signalling pathways in reaction to shear stress. Current Opinion in Biomedical Engineering vol. 5, 96-104.
10.1016/j.cobme.2018.03.003
Seneviratne AN, Edsfeldt A, Cole JE, Kassiteridi C, Swart M, Park I, Green P, Khoyratty T et al.(2017). Interferon Regulatory Factor 5 Controls Necrotic Core Formation in Atherosclerotic Lesions by Impairing Efferocytosis. Circulation vol. 136, (12) 1140-1154.
10.1161/CIRCULATIONAHA.117.027844
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49545
Denis J-F, Scheckenbach KEL, Pfenniger A, Meens MJ, Krams R, Miquerol L, Taffet S, Chanson M et al.(2017). Connexin40 controls endothelial activation by dampening NFκB activation. Oncotarget vol. 8, (31) 50972-50986.
10.18632/oncotarget.16438
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58297
Poulsen CB, Pedrigi R, Holm N, Pareek N, Kilic I, Post AL, Di Mario C, Bentzon J et al. (2017). COMPARISON OF IN VIVO OPTICAL COHERENCE TOMOGRAPHY DERIVED PLAQUE PHENOTYPE AND BURDEN WITH HISTOLOGY IN A PORCINE MODEL OF ADVANCED CORONARY ATHEROSCLEROSIS. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 69, 1072-1072.
Serbanovic-Canic J, de Luca A, Warboys C, Ferreira PF, Luong LA, Hsiao S, Gauci I, Mahmoud M et al.(2016). Zebrafish Model for Functional Screening of Flow-Responsive Genes. Arterioscler Thromb Vasc Biol vol. 37, (1) 130-143.
10.1161/ATVBAHA.116.308502
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49547
Pedrigi RM, Papadimitriou KI, Kondiboyina A, Sidhu S, Chau J, Patel MB, Baeriswyl DC, Drakakis EM et al.(2016). Disturbed Cyclical Stretch of Endothelial Cells Promotes Nuclear Expression of the Pro-Atherogenic Transcription Factor NF-κB. Ann Biomed Eng vol. 45, (4) 898-909.
10.1007/s10439-016-1750-z
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58325
Pedrigi RM, Mehta V, Bovens SM, Mohri Z, Poulsen CB, Gsell W, Tremoleda JL, Towhidi L et al.(2016). Influence of shear stress magnitude and direction on atherosclerotic plaque composition. Royal Society Open Science vol. 3, (10)
10.1098/rsos.160588
https://qmro.qmul.ac.uk/xmlui/handle/123456789/17883
Kis Z, Rodin T, Zafar A, Lai Z, Freke G, Fleck O, Del Rio Hernandez A, Towhidi L et al.(2016). Development of a synthetic gene network to modulate gene expression by mechanical forces. Sci Rep vol. 6, 29643-29643.
10.1038/srep29643
https://qmro.qmul.ac.uk/xmlui/handle/123456789/49546
Krams RM, Pedrigi RM, Kis Z (2016). A novel assay for regulating transcription factors by flow. CARDIOVASCULAR RESEARCH. vol. 111, S117-S117.
Towhidi L, Khodadadi D, Maimari N, Pedrigi RM, Ip H, Kis Z, Kwak BR, Petrova TW et al.(2016). Comparison between direct and reverse electroporation of cells in situ: A simulation study. Physiological Reports vol. 4, (6) 1-14.
10.14814/phy2.12673
Seneviratne AN, Cole JE, Goddard ME, Park I, Mohri Z, Sansom S, Udalova I, Krams R et al.(2016). Corrigendum to "Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques" [J Mol Cell Cardiol, 89B (2015) 168-172]. Journal of Molecular and Cellular Cardiology vol. 91,
10.1016/j.yjmcc.2015.12.029
Maimari N, Pedrigi RM, Russo A, Broda K, Krams R(2016). Integration of flow studies for robust selection of mechanoresponsive genes. Thrombosis and Haemostasis vol. 115, (3) 474-483.
10.1160/TH15-09-0704
Antonacci G, Pedrigi R, Krams R, Torok P (2016). Quantification of plaque stiffness by Brillouin microscopy (Conference Presentation). OPTICAL ELASTOGRAPHY AND TISSUE BIOMECHANICS III. vol. 9710,
10.1117/12.2228312
Seneviratne AN, Cole JE, Goddard ME, Park I, Mohri Z, Sansom S, Udalova I, Krams R et al.(2015). Low shear stress induces M1 macrophage polarization in murine thin-cap atherosclerotic plaques. Journal of Molecular and Cellular Cardiology vol. 89, 168-172.
10.1016/j.yjmcc.2015.10.034
Antonacci G, Pedrigi RM, Kondiboyina A, Mehta VV, De Silva R, Paterson C, Krams R, Török P(2015). Quantification of plaque stiffness by Brillouin microscopy in experimental thin cap fibroatheroma. Journal of the Royal Society Interface vol. 12, (112)
10.1098/rsif.2015.0843
Pfenniger A, Meens MJ, Pedrigi RM, Foglia B, Sutter E, Pelli G, Rochemont V, Petrova TV et al.(2015). Shear stress-induced atherosclerotic plaque composition in ApoE<sup>-/-</sup> mice is modulated by connexin37. Atherosclerosis vol. 243, (1) 1-10.
10.1016/j.atherosclerosis.2015.08.029
Shamout FE, Pouliopoulos AN, Lee P, Bonaccorsi S, Towhidi L, Krams R, Choi JJ(2015). Enhancement of Non-Invasive Trans-Membrane Drug Delivery Using Ultrasound and Microbubbles During Physiologically Relevant Flow. Ultrasound in Medicine and Biology vol. 41, (9) 2435-2448.
10.1016/j.ultrasmedbio.2015.05.003
Dent MR, López-Duarte I, Dickson CJ, Geoghegan ND, Cooper JM, Gould IR, Krams R, Bull JA et al.(2015). Imaging phase separation in model lipid membranes through the use of BODIPY based molecular rotors. Physical Chemistry Chemical Physics vol. 17, (28) 18393-18402.
10.1039/c5cp01937k
Pereira GDC, Krams R (2015). FLOW CHARACTERISTICS ENHANCED BY THE COMPLIANT ARTERIES AND THEIR EFFECTS IN VULNERABLE PLAQUE FORMATION. HEART. vol. 101,
10.1136/heartjnl-2015-308066.182
Kis Z, Pereira HSA, Homma T, Pedrigi RM, Krams R(2015). Mammalian synthetic biology: Emerging medical applications. Journal of the Royal Society Interface vol. 12, (106)
10.1098/rsif.2014.1000
Poulsen CB, Pedrigi RM, Mehta VV, Post A, Pareek N, Holm NR, Kilic D, El-Bahnasawi M et al. (2015). INDUCTION OF PERTURBED SHEAR STRESS LEADS TO FOCAL ADVANCED ATHEROSCLEROTIC PLAQUE FORMATION IN TRANSGENIC MINIPIGS WITH HYPERCHOLESTEROLEMIA. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 65, A1927-A1927.
10.1016/S0735-1097(15)61927-1
Villanueva ME, Pereira HSA, Rajyaguru J, Krams R, Chachuat B (2015). Bifurcation and stability analysis of nonlinear dynamic systems using complete search. Computing and Systems Technology Division 2015 - Core Programming Area at the 2015 AIChE Annual Meeting. vol. 2, 627-628.
Poulsen CB, Mehta VV, Holm NR, Pareek N, Post AL, Kilic ID, Banya WAS, Dall'Ara G et al.(2015). Inducing persistent flow disturbances accelerates atherogenesis and promotes thin cap fibroatheroma development in D374Y-PCSK9 hypercholesterolemic minipigs. Circulation vol. 132, (11) 1003-1012.
10.1161/CIRCULATIONAHA.115.016270
Mohri Z, Rowland EM, Clarke LA, De Luca A, Peiffer V, Krams R, Sherwin SJ, Weinberg PD(2014). Elevated uptake of plasma macromolecules by regions of arterial wall predisposed to plaque instability in a mouse model. PLoS ONE vol. 9, (12)
10.1371/journal.pone.0115728
Homma T, Caurette P, Silva HJ, Yamada I, Makrydaki E, Bovens S, Pedrigi R, Petretto EG et al. (2014). TRANSCRIPTOME ANALYSIS OF LOCAL SHEAR DEPENDENT GENE EXPRESSION IN ENDOTHELIAL CELLS DURING THIN-CAP FIBROATHEROMA(TCFA) DEVELOPMENT. ATHEROSCLEROSIS. vol. 237, E9-E9.
10.1016/j.atherosclerosis.2014.10.057
Maimari N, Broda K, Kakas A, Krams R, Russo A(2014). Symbolic Representation and Inference of Regulatory Network Structures. Logical Modeling of Biological Systems,
Cuhlmann S, Gsell W, Van der Heiden K, Habib J, Tremoleda JL, Khalil M, Turkheimer F, Meens MJ et al.(2014). In Vivo Mapping of Vascular Inflammation Using the Translocator Protein Tracer 18F-FEDAA1106. Mol Imaging vol. 13, (6)
10.2310/7290.2014.00014
Caro CG, Seneviratne A, Heraty KB, Monaco C, Burke MG, Krams R, Chang CC, Gilson P et al.(2014). Erratum: Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: Influence of intraluminal flow (Journal of the Royal Society Interface (2013) 10, (20130578) DOI: 10.1098/rsif.2013.0578). Journal of the Royal Society Interface vol. 11, (92)
10.1098/rsif.2013.1156
Mohri Z, Rowland E, Clarke LA, De Luca A, Krams R, Weinberg PD (2014). ELEVATED ARTERIAL WALL PERMEABILITY MAY CAUSE VULNERABLE PLAQUE FORMATION IN MICE. ATHEROSCLEROSIS. vol. 232, E6-E6.
10.1016/j.atherosclerosis.2013.11.015
Pereira G, Krams R, van Wachem B (2014). Modelling the Mechanics of the Circulation: Blood Rheology and Atherosclerosis. BIOPHYSICAL JOURNAL. vol. 106, 376A-376A.
10.1016/j.bpj.2013.11.2127
Kis Z, Towhidi L, Ip H, Drakakis E, Bharath A, Krams R(2014). An In situ electroporation and flow device for mechanotransduction studies. Microarrays: Principles, Applications and Technologies,
Kwak BR, Bäck M, Bochaton-Piallat ML, Caligiuri G, Daemen MJAP, Davies PF, Hoefer IE, Holvoet P et al.(2014). Biomechanical factors in atherosclerosis: Mechanisms and clinical implications. European Heart Journal vol. 35, (43) 3013-3020.
10.1093/eurheartj/ehu353
Cuhlmann S, Gsell W, Van Der Heiden K, Habib J, Tremoleda JL, Khalil M, Turkheimer F, Meens MJ et al.(2014). In vivo mapping of vascular inflammation using the translocator protein tracer <sup>18</sup>F-FEDAA1106. Molecular Imaging vol. 13, (6)
10.2310/7290.2014.00014
Pedrigi RM, De Silva R, Bovens SM, Mehta VV, Petretto E, Krams R(2014). Thin-cap fibroatheroma rupture is associated with a fine interplay of shear and wall stress. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 34, (10) 2224-2231.
10.1161/ATVBAHA.114.303426
Caro CG, Seneviratne A, Heraty KB, Monaco C, Burke MG, Krams R, Chang CC, Coppola G et al.(2013). Intimal hyperplasia following implantation of helical-centreline and straight-centreline stents in common carotid arteries in healthy pigs: Influence of intraluminal flow. Journal of the Royal Society Interface vol. 10, (89)
10.1098/rsif.2013.0578
Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Jauhiainen S et al.(2013). Stabilization of atherosclerotic plaques: An update. European Heart Journal vol. 34, (42) 3251-3258.
10.1093/eurheartj/eht301
Maimari N, Turliuc CR, Broda K, Kakas A, Krams R, Russo A (2013). ARNI: Abductive inference of complex regulatory network structures. Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). vol. 8130 LNBI, 235-237.
Seneviratne AN, Cole JE, Goddard ME, Udalova I, Krams R, Monaco C (2013). M1 macrophages are an early feature of shear stress modulated vulnerable atherosclerotic plaques. EUROPEAN HEART JOURNAL. vol. 34, 443-443.
Foin N, Sen S, Petraco R, Nijjer S, Torii R, Kousera C, Broyd C, Mehta V et al.(2013). Method for percutaneously introducing, and removing, anatomical stenosis of predetermined severity in vivo: The "stenotic stent". Journal of Cardiovascular Translational Research vol. 6, (4) 640-648.
10.1007/s12265-013-9476-x
Bovens SM, Foin N, O'Clery N, Van der Heiden K, Cuhlmann S, Carlsen H, Barahona M, Evans PC et al. (2013). Shear stress and nitric oxide transport affect NFkB dynamics in endothelial cells. EUROPEAN HEART JOURNAL. vol. 34, 110-110.
Frueh J, Maimari N, Homma T, Bovens SM, Pedrigi RM, Towhidi L, Krams R(2013). Systems biology of the functional and dysfunctional endothelium. Cardiovascular Research vol. 99, (2) 334-341.
10.1093/cvr/cvt108
Seneviratne A, Cole J, Goddard M, Udalova I, Krams R, Monaco C (2013). M1 MACROPHAGES AND IRF5 EXACERBATE ATHEROSCLEROTIC DISEASE. HEART. vol. 99, A103-A103.
10.1136/heartjnl-2013-304019.181
Olivon VC, Fraga-Silva RA, Segers D, Demougeot C, de Oliveira AM, Savergnini SS, Berthelot A, de Crom R et al.(2013). Arginase inhibition prevents the low shear stress-induced development of vulnerable atherosclerotic plaques in ApoE-/- mice. Atherosclerosis vol. 227, (2) 236-243.
10.1016/j.atherosclerosis.2012.12.014
Harrison M, Smith E, Ross E, Krams R, Segers D, Buckley CD, Nash GB, Rainger GE(2013). The role of platelet-endothelial cell adhesion molecule-1 in atheroma formation varies depending on the site-specific hemodynamic environment. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 33, (4) 694-701.
10.1161/ATVBAHA.112.300379
Shami A, Gustafsson R, Kalamajski S, Krams R, Segers D, Rauch U, Roos G, Nilsson J et al.(2013). Fibromodulin deficiency reduces low-density lipoprotein accumulation in atherosclerotic plaques in apolipoprotein E-null mice. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 33, (2) 354-361.
10.1161/ATVBAHA.112.300723
Da Silva RF, Gambillara V, Krams R, Stergiopulos N(2012). Modulation of arginases by different patterns of shear stress: New signaling pathway in atherogenesis?. Computer Methods in Biomechanics and Biomedical Engineering vol. 10, (SUPPL. 1) 77-78.
10.1080/10255840701478497
Falck-Hansen MA, Goddard ME, Cole JE, Astola N, Cross AJ, Krams R, Monaco C (2012). MACROPHAGE ACTIVATION DURING CHRONIC INFLAMMATION IN ATHEROSCLEROSIS. ATHEROSCLEROSIS. vol. 225, E3-E3.
10.1016/j.atherosclerosis.2012.10.010
Seneviratne AN, Cole JE, Goddard ME, Mohri Z, Krams R, Monaco C (2012). MACROPHAGE POLARISATION IN SHEAR STRESS MODULATED ATHEROSCLEROTIC PLAQUE VULNERABILITY. ATHEROSCLEROSIS. vol. 225, E2-E2.
10.1016/j.atherosclerosis.2012.10.005
Foin N, Sen S, Petraco R, Torii R, Nijjer S, Xu YX, Mehta V, Mayet J et al. (2012). Investigation of Fractional Flow Reserve Correlation with Direct Anatomical Parameters Using a Percutaneous Model of Coronary Artery Stenosis. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 60, B67-B67.
10.1016/j.jacc.2012.08.254
Pfenniger A, Wong C, Sutter E, Cuhlmann S, Dunoyer-Geindre S, Mach F, Horrevoets AJ, Evans PC et al.(2012). Shear stress modulates the expression of the atheroprotective protein Cx37 in endothelial cells. Journal of Molecular and Cellular Cardiology vol. 53, (2) 299-309.
10.1016/j.yjmcc.2012.05.011
Frueh J, Maimari N, Lui Y, Kis Z, Mehta V, Pormehr N, Grant C, Chalkias E et al.(2012). Systems and synthetic biology of the vessel wall. FEBS Letters vol. 586, (15) 2164-2170.
10.1016/j.febslet.2012.04.031
Van Bochove GS, Sanders HMHF, De Smet M, Keizer HM, Mulder WJM, Krams R, Strijkers GJ, Nicolay K(2012). Molecular MR imaging of collagen in mouse atherosclerosis by using paramagnetic CNA35 micelles. European Journal of Inorganic Chemistry (12) 2115-2125.
10.1002/ejic.201200010
Caro CG, Seneviratne A, Monaco C, Hou D, Singh J, Gilson P, Burke MG, Heraty KB et al. (2012). Arterial stent-associated intimal hyperplasia and wall hypoxia. CARDIOVASCULAR RESEARCH. vol. 93, S116-S116.
Falck-Hansen M, Goddard ME, Cole JE, Astola N, Cross AJ, Krams R, Monaco C (2012). Expression of the regulatory receptor CD200R on macrophages is regulated by polarization signals in atherosclerosis. CARDIOVASCULAR RESEARCH. vol. 93, S19-S19.
Seneviratne AN, Cole JE, Goddard ME, Mohri Z, Cross AJ, Krams R, Monaco C (2012). Macrophage heterogeneity in shear stress modulated atherosclerotic plaque development. CARDIOVASCULAR RESEARCH. vol. 93, S51-S51.
Kuhlmann MT, Cuhlmann S, Hoppe I, Krams R, Evans PC, Strijkers GJ, Nicolay K, Hermann S et al.(2012). Implantation of a carotid cuff for triggering shear-stress induced atherosclerosis in mice. Journal of Visualized Experiments (59) 1-6.
10.3791/3308
Foin N, Torii R, Mortier P, De Beule M, Viceconte N, Chan PH, Davies JE, Xu XY et al.(2012). Kissing balloon or sequential dilation of the side branch and main vessel for provisional stenting of bifurcations: Lessons from micro-computed tomography and computational simulations. JACC: Cardiovascular Interventions vol. 5, (1) 47-56.
10.1016/j.jcin.2011.08.019
Falck-Hansen M, Goddard ME, Cole JE, Astola N, Cross AJ, Krams R, Monaco C (2011). Expression of the regulatory receptor CD200R on macrophages is regulated by polarization signals in atherosclerosis. IMMUNOLOGY. vol. 135, 109-109.
Foin N, Secco G, Sen S, Davies JE, Krams R, Di Mario C (2011). Bench Micro-CT study and OCT Experience of a Final Proximal Post-dilatation to Optimize Results in Bifurcation Stenting. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 58, B87-B87.
Foin N, Torii R, Mortier P, De Beule M, Viceconte N, Davies JE, Xu XY, Krams R et al. (2011). Sequential Side Branch and Main Vessel Dilatation instead of Kissing Balloon after Provisional Bifurcation Stenting: Lessons from Micro-CT and Computational Simulations. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 58, B82-B82.
Gsell W, Cuhlmann S, Van der Heiden K, Tremoleda JL, Khalil M, Clark J, Bird J, Jones H et al.(2011). (18)FEDAA is a more specific probe than (18)FDG for imaging vascular inflammation. EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING vol. 38, S210-S210.
Foin N, Secco GG, Ghilencea L, Krams R, Di Mario C(2011). Final proximal post-dilatation is necessary after kissing balloon in bifurcation stenting. EuroIntervention vol. 7, (5) 597-604.
10.4244/EIJV7I5A96
Halliday I, Atherton M, Care CM, Collins MW, Evans D, Evans PC, Hose DR, Khir AW et al.(2011). Multi-scale interaction of particulate flow and the artery wall. Medical Engineering and Physics vol. 33, (7) 840-848.
10.1016/j.medengphy.2010.09.007
Pfenniger A, Sutter E, Cuhlmann S, Evans PC, Krams R, Kwak BR (2011). Endothelial Cx37 expression is regulated by the shear stress responsive transcription factor KLF2. EUROPEAN HEART JOURNAL. vol. 32, 937-937.
Foin N, Viceconte N, Chan PH, Lindsay AC, Krams R, Di Mario C(2011). Jailed side branches: Fate of unapposed struts studied with 3D frequency-domain optical coherence tomography. Journal of Cardiovascular Medicine vol. 12, (8) 581-582.
10.2459/JCM.0b013e32834916e3
De Crom R, Leenen P, Nicolay K, Krams R(2011). Shear stress is a major determinant for getting a heart attack. Hart Bulletin vol. 42, (3) 67-70.
Cuhlmann S, Van Der Heiden K, Saliba D, Tremoleda JL, Khalil M, Zakkar M, Chaudhury H, Luong LA et al.(2011). Disturbed blood flow induces rela expression via c-Jun N-terminal kinase 1: A novel mode of NF-κB regulation that promotes arterial inflammation. Circulation Research vol. 108, (8) 950-959.
10.1161/CIRCRESAHA.110.233841
Foin N, Secco G, Ghilencea L, Krams R, Di Mario C (2011). FINAL PROXIMAL POST-DILATATION IS NECESSARY AFTER KISSING BALLOON IN BIFURCATIONS STENTING. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 57, E1721-E1721.
10.1016/S0735-1097(11)61721-X
Poelma C, Mari JM, Foin N, Tang MX, Krams R, Caro CG, Weinberg PD, Westerweel J (2011). 3D Flow reconstruction using ultrasound PIV. Experiments in Fluids. vol. 50, 777-785.
10.1007/s00348-009-0781-8
Olivon VC, Segers D, de Oliveira AM, Demougeot C, Bertholet A, de Crom R, Krams R, Stergiopulos N et al. (2011). Effects of arginase inhibition on shear stress-induced plaque size and composition. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. vol. 41, 6-6.
Zakkar M, Luong LA, Chaudhury H, Ruud O, Punjabi PP, Anderson JR, Mullholand JW, Clements AT et al.(2011). Dexamethasone arterializes venous endothelial cells by inducing mitogen-activated protein kinase phosphatase-1: A novel antiinflammatory treatment for vein grafts?. Circulation vol. 123, (5) 524-532.
10.1161/CIRCULATIONAHA.110.979542
Segers D, Lipton JA, Leenen PJM, Cheng C, Tempel D, Pasterkamp G, Moll FL, de Crom R et al.(2011). Atherosclerotic Plaque Stability Is Affected by the Chemokine CXCL10 in Both Mice and Humans. Int J Inflam vol. 2011,
10.4061/2011/936109
Van Bochove GS, Paulis LEM, Segers D, Mulder WJM, Krams R, Nicolay K, Strijkers GJ(2011). Contrast enhancement by differently sized paramagnetic MRI contrast agents in mice with two phenotypes of atherosclerotic plaque. Contrast Media and Molecular Imaging vol. 6, (1) 35-45.
10.1002/cmmi.402
Ylä-Herttuala S, Bentzon JF, Daemen M, Falk E, Garcia-Garcia HM, Herrmann J, Hoefer I, Wouter Jukema J et al.(2011). Stabilisation of atherosclerotic plaques position paper of the european society of cardiology (ESC) working group on atherosclerosis and vascular biology. Thrombosis and Haemostasis vol. 106, (1) 1-19.
10.1160/TH10-12-0784
Debernardi N, Roijers RB, Krams R, De Crom R, Mutsaers PHA, Van Der Vusse GJ(2010). Microcalcifications in atherosclerotic lesion of apolipoprotein E-deficient mouse. International Journal of Experimental Pathology vol. 91, (6) 485-494.
10.1111/j.1365-2613.2010.00729.x
Pfenniger A, Galan K, Wong C, Cuhlmann S, Evans PC, Krams R, Kwak BR (2010). Shear Stress Modulates the Expression of the Vasoprotective Protein Cx37 in Endothelial Cells. CIRCULATION. vol. 122,
Da Silva RF, Olivon VC, Segers D, De Crom R, Krams R, Stergiopuloss N (2010). Ex vivo and in vivo regulation of arginase in response to wall shear stress. IFMBE Proceedings. vol. 29, 753-756.
10.1007/978-3-642-13039-7_190
Plata AM, Sherwin SJ, Krams R(2010). Endothelial nitric oxide production and transport in flow chambers: The importance of convection. Annals of Biomedical Engineering vol. 38, (9) 2805-2816.
10.1007/s10439-010-0039-x
Zakkar M, Punjabi P, Anderson J, Smith P, Krams R, Haskard D, Evans P (2010). Dexamethasone arterializes venous endothelial cells by inducing MAP Kinase phosphatase-1 (MKP-1). A novel anti-inflammatory treatment for vein grafts. BRITISH JOURNAL OF SURGERY. vol. 97, S12-S13.
Krams R, Cuhlmann S, Foin N, Evans P(2010). Shear stress, inflammation and Atherosclerosis. Artery Research vol. 4, (2) 41-46.
10.1016/j.artres.2010.03.002
Van Bochove GS, Straathof R, Krams R, Nicolay K, Strijkers GJ(2010). MRI-determined carotid artery flow velocities and wall shear stress in a mouse model of vulnerable and stable atherosclerotic plaque. Magnetic Resonance Materials in Physics, Biology and Medicine vol. 23, (2) 77-84.
10.1007/s10334-010-0200-4
Friedman MH, Krams R, Chandran KB (2010). Flow Interactions with Cells and Tissues: Cardiovascular Flows and Fluid-Structure Interactions. ANNALS OF BIOMEDICAL ENGINEERING. vol. 38, 1178-1187.
10.1007/s10439-010-9900-1
Friedman MH, Krams R, Chandran KB(2010). Flow interactions with cells and tissues: Cardiovascular flows and fluid-structure interactions: Sixth international bio-fluid mechanics symposium and workshop, March 28-30, 2008, Pasadena, California. Annals of Biomedical Engineering vol. 38, (3) 1178-1187.
10.1007/s10439-010-9900-1
Chaudhury H, Zakkar M, Boyle J, Cuhlmann S, Van Der Heiden K, Luong LA, Davis J, Platt A et al.(2010). C-Jun N-terminal kinase primes endothelial cells at atheroprone sites for apoptosis. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 30, (3) 546-553.
10.1161/ATVBAHA.109.201368
Helderman F, Manoch IJ, Breeuwer, Kose U, Boersma H, Van Sambeek MRHM, Pattynama PMT, SchoutenO. et al.(2010). Predicting patient-specific expansion of abdominal aortic aneurysms. European Journal of Vascular and Endovascular Surgery vol. 40, (1) 47-53.
10.1016/j.ejvs.2010.02.017
Zakkar M, van der Heiden K, Chaudhury H, Krams R, Haskard DO, Mason JC, Evans PC (2009). ACTIVATION OF NF-E2 RELATED FACTOR-2 (NRF2) PROTECTS ARTERIES FROM EXHIBITING A PRO-INFLAMMATORY STATE. HEART. vol. 95,
10.1136/hrt.2009.181669m
Chaudhury HA, Zakkar M, Boyle J, Dennis J, van der Heiden K, Luong L, Cuhlmann S, Mason JM et al. (2009). ENDOTHELIAL CELLS AT ATHEROSUSCEPTIBLE SITES EXPRESS ACTIVATED C-JUN N-TERMINAL KINASE WHICH INDUCES PRO-APOPTOTIC MOLECULES. HEART. vol. 95,
10.1136/hrt.2009.178137f
Cuhlmann S, van der Heiden K, Zakkar M, Chaudhury H, Luong LA, Mason JM, Haskard DO, Krams R et al. (2009). HIGH SHEAR STRESS SUPPRESSES THE EXPRESSION AND ACTIVITY OF NF-KAPPAB TRANSCRIPTION FACTORS IN ARTERIAL ENDOTHELIUM. HEART. vol. 95,
10.1136/hrt.2009.178137h
Foin N, Plata-Garcia A, Cuhlmann S, Evans PC, Caro CG, Krams R (2009). SHEAR STRESS AND NITRIC OXIDE TRANSPORT AFFECT NF-KB DYNAMICS IN ENDOTHELIAL CELLS. HEART. vol. 95,
10.1136/hrt.2009.178137m
Zakkar M, Van Der Heiden K, Luong LA, Chaudhury H, Cuhlmann S, Hamdulay SS, Krams R, Edirisinghe I et al.(2009). Activation of Nrf2 in endothelial cells protects arteries from exhibiting a proinflammatory state. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 29, (11) 1851-1857.
10.1161/ATVBAHA.109.193375
Foin N, Plata-Garcia A, Qin Q, Cuhlmann S, Evans PC, Caro CG, Krams R (2009). Shear Stress and Nitric Oxide Transport Affect NF-kappa B Dynamics In Endothelial Cells. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. vol. 29, E78-E78.
Cheng C, Tempel D, van Haperen R, van Damme L, Algür M, Krams R, de Crom R(2009). Activation of MMP8 and MMP13 by angiotensin II correlates to severe intra-plaque hemorrhages and collagen breakdown in atherosclerotic lesions with a vulnerable phenotype. Atherosclerosis vol. 204, (1) 26-33.
10.1016/j.atherosclerosis.2009.01.025
de Crom R, Cheng C, Helderman F, Krams R(2009). Large variations in absolute wall shear stress levels within one species and between species. Atherosclerosis vol. 204, (1) 16-17.
10.1016/j.atherosclerosis.2008.08.010
Susa D, van de Engel S, van Damme LCA, Roest HP, Krams R, IJzermans JNM, de Bruin RWF(2009). Donor pre-treatment with tacrolimus reduces transplant vasculopathy. Pharmacological Research vol. 59, (4) 273-278.
10.1016/j.phrs.2008.12.006
Foin N, Plata-Garcia A, Cuhlmann S, Evans P, Caro C, Krams R(2009). SHEAR STRESS AND MASS TRANSPORT AFFECTS NF kappa B DYNAMICS IN ENDOTHELIAL CELLS. JOURNAL OF PHYSIOLOGICAL SCIENCES vol. 59, 324-324.
Segers D, Weinberg P, Krams R(2008). Atherosclerosis: Cell biology and lipoproteins - Shear stress and inflammation in plaque formation: New evidence. Current Opinion in Lipidology vol. 19, (6) 627-628.
10.1097/MOL.0b013e328318db32
Krams R, Breeuwer M, van de Vosse F(2008). Personalised imaging and biomechanical modelling of large vessels. Medical and Biological Engineering and Computing vol. 46, (11) 1057-1058.
10.1007/s11517-008-0417-9
Robbers-Visser D, Helderman F, Strengers JL, Van Osch-Gevers L, Kapusta L, Pattynama PM, Bogers AJ, Krams R et al.(2008). Pulmonary artery size and function after fontan operation at a young age. Journal of Magnetic Resonance Imaging vol. 28, (5) 1101-1107.
10.1002/jmri.21544
Ridger V, Krams R, Carpi A, Evans PC(2008). Hemodynamic parameters regulating vascular inflammation and atherosclerosis: A brief update. Biomedicine and Pharmacotherapy vol. 62, (8) 536-540.
10.1016/j.biopha.2008.07.053
Zakkar M, Chaudhury H, Sandvik G, Enesa K, Luong LA, Cuhlmann S, Mason JC, Krams R et al.(2008). Increased endothelial mitogen-activated protein kinase phosphatase-1 expression suppresses proinflammatory activation at sites that are resistant to atherosclerosis. Circulation Research vol. 103, (7) 726-732.
10.1161/CIRCRESAHA.108.183913
Breeuwer M, de Putter S, Kose U, Speelman L, Visser K, Gerritsen F, Hoogeveen R, Krams R et al.(2008). Towards patient-specific risk assessment of abdominal aortic aneurysm. Medical and Biological Engineering and Computing vol. 46, (11) 1085-1095.
10.1007/s11517-008-0393-0
Zakkar M, Chaudhury H, Krams R, Mason JC, Clark AR, Haskard DO, Evans PC (2008). Map kinase phosphatase-1 suppresses endothelial activation in regions of the arterial tree that are resistant to atherosclerosis. ATHEROSCLEROSIS. vol. 199, 465-465.
10.1016/j.atherosclerosis.2008.05.006
Helderman F, Manoch IJ, Breeuwer M, Kose U, Schouten O, Sambeek MRM, Poldermans D, Pattynama PTM et al.(2008). A numerical model to predict abdominal aortic aneurysm expansion based on local wall stress and stiffness. Medical and Biological Engineering and Computing vol. 46, (11) 1121-1127.
10.1007/s11517-008-0358-3
Cheng C, Tempel D, Oostlander A, Helderman F, Gijsen F, Wentzel J, Van Haperen R, Haitsma DB et al.(2008). Rapamycin modulates the eNOS vs. shear stress relationship. Cardiovascular Research vol. 78, (1) 123-129.
10.1093/cvr/cvm103
da Silva RF, Olivon VC, Segers D, de Crom R, Krams R, Stergiopulos N (2008). Role of arginase pathway in response to shear stress: new potential therapeutic targets for atherosclerosis?. EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. vol. 38, 36-36.
Foin N, Evans P, Krams R(2008). Atherosclerosis: Cell biology and lipoproteins - New developments in imaging of inflammation of the vulnerable plaque. Current Opinion in Lipidology vol. 19, (1) 98-100.
10.1097/MOL.0b013e3282f41b60
Van der Heiden K, Hierck BP, Krams R, de Crom R, Cheng C, Baiker M, Pourquie MJBM, Alkemade FE et al.(2008). Endothelial primary cilia in areas of disturbed flow are at the base of atherosclerosis. Atherosclerosis vol. 196, (2) 542-550.
10.1016/j.atherosclerosis.2007.05.030
Segers D, Garcia-Garcia HM, Cheng C, De Crom R, Krams R, Wentzel JJ, Van der Steen AFW, Serruys PW et al.(2008). A primer on the immune system in the pathogenesis and treatment of atherosclerosis. EuroIntervention vol. 4, (3) 378-390.
10.4244/EIJV4I3A67
Cheng C, Helderman F, Tempel D, Segers D, Hierck B, Poelmann R, van Tol A, Duncker DJ et al.(2007). Large variations in absolute wall shear stress levels within one species and between species. Atherosclerosis vol. 195, (2) 225-235.
10.1016/j.atherosclerosis.2006.11.019
Goertz DE, Frijlink ME, Tempel D, Bhagwandas V, Gisolf A, Krams R, de Jong N, van der Steen AFW(2007). Subharmonic Contrast Intravascular Ultrasound for Vasa Vasorum Imaging. Ultrasound in Medicine and Biology vol. 33, (12) 1859-1872.
10.1016/j.ultrasmedbio.2007.05.023
Goertz DE, Frijlink ME, Tempel D, Krams R, De Jong N, Van Der Steen AFW (2007). Subharmonic contrast intravascular ultrasound. Proceedings - IEEE Ultrasonics Symposium. 1065-1068.
10.1109/ULTSYM.2007.269
Segers D, de Crom R, Leenen P, Pasterkamp G, Krams R (2007). The chemokine CXCL10 is involved in the development of atherosclerotic plaque vulnerability. CIRCULATION. vol. 116, 172-172.
Helderman F, Segers D, De Crom R, Hierck BP, Poelmann RE, Evans PC, Krams R(2007). Effect of shear stress on vascular inflammation and plaque development. Current Opinion in Lipidology vol. 18, (5) 527-533.
10.1097/MOL.0b013e3282ef7716
Susa D, van den Engel S, van Damme LA, Roest HP, Krams R, IJiermans JNM, De Bruin RWF (2007). Donor pre-treatment with tacrolimus reduces transplant vasculopathy. TRANSPLANT INTERNATIONAL. vol. 20, 141-141.
Jackson CL, Bennett MR, Biessen EAL, Johnson JL, Krams R(2007). Assessment of unstable atherosclerosis in mice. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 27, (4) 714-720.
10.1161/01.ATV.0000261873.86623.e1
Cheng C, Tempel D, Van Haperen R, De Boer HC, Segers D, Huisman M, Van Zonneveld AJ, Leenen PJM et al.(2007). Shear stress-induced changes in atherosclerotic plaque composition are modulated by chemokines. Journal of Clinical Investigation vol. 117, (3) 616-626.
10.1172/JCI28180
Segers D, Helderman F, Cheng C, Van Damme LCA, Tempel D, Boersma E, Serruys PW, De Crom R et al.(2007). Gelatinolytic activity in atherosclerotic plaques is highly localized and is associated with both macrophages and smooth muscle cells in vivo. Circulation vol. 115, (5) 609-616.
10.1161/CIRCULATIONAHA.106.636415
Kofflard MJ, Michels M, Krams R, Kliffen M, Geleijnse ML, Ten Cate FJ, Serruys PW(2007). Coronary flow reserve in hypertrophic cardiomyopathy: Relation with microvascular dysfunction and pathophysiological characteristics. Netherlands Heart Journal vol. 15, (6) 209-215.
10.1007/BF03085982
Wentzel JJ, Gijsen FJH, Krams R, de Crom R, Cheng C, Groen HC, Van Der Giessen AG, Van Der Steen AFW et al.(2007). Shear stress and the vulnerable plaque. Handbook of the Vulnerable Plaque, Second Edition,
Goertz DE, Frijlink ME, Krams R, De Jong N, Van Der Steen AFW(2007). Vasa vasorum and molecular imaging of atherosclerotic plaques using nonlinear contrast intravascular ultrasound. Netherlands Heart Journal vol. 15, (2) 77-80.
10.1007/BF03085959
Krams R, Schaar J, Helderman F, Cheng C, Gourabi BM, Van Damme LCA, Segers D, Regar E et al.(2006). Visualization of the vulnerable plaque. Cardiovascular Research: New Technologies, Methods, and Applications,
Frijlink ME, Goertz DE, Vos HJ, Tesselaar E, Blacquière G, Gisolf A, Krams R, van der Steen AFW(2006). Harmonic intravascular ultrasound imaging with a dual-frequency catheter. Ultrasound in Medicine and Biology vol. 32, (11) 1649-1654.
10.1016/j.ultrasmedbio.2006.05.024
Cheng C, Tempel D, Van Der Baan A, Krams R, Daemen MJAP, Van Haperen R, Grosveld F, De Crom R(2006). Response to letter regarding article, "atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress" [2]. Circulation vol. 114, (22)
10.1161/CIRCULATIONAHA.106.658302
Lipton J, Segers D, Cheng C, Duckers H, Krams R, Tempel D, Busser E, De Kleijn D et al. (2006). High IP-10 levels identify plaques with a vulnerable phenotype. CIRCULATION. vol. 114, 287-288.
Frijlink ME, Goertz DE, Van Damme LCA, Krams R, Van Der Steen AFW(2006). Intravascular ultrasound tissue harmonic imaging in vivo. IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control vol. 53, (10) 1844-1851.
10.1109/TUFFC.2006.116
Goertz DE, Frijlink ME, Tempel D, Van Damme LCA, Krams R, Schaar JA, Ten Cate FJ, Serruys PW et al.(2006). Contrast harmonic intravascular ultrasound: A feasibility study for vasa vasorum imaging. Investigative Radiology vol. 41, (8) 631-638.
10.1097/01.rli.0000229773.11715.da
Krams R, Cheng C, Helderman F, Verheye S, van Damme LCA, Mousavi Gourabi B, Tempel D, Segers D et al.(2006). Shear stress is associated with markers of plaque vulnerability and MMP-9 activity. EuroIntervention vol. 2, (2) 250-256.
Cheng C, Tempel D, van Haperen R, van der Baan A, Grosveld F, Daemen MJAP, Krams R, de Crom R(2006). Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. CIRCULATION vol. 113, (23) 2744-2753.
10.1161/CIRCULATIONAHA.105.590018
Cheng C, Tempel D, Van Haperen R, Van Der Baan A, Grosveld F, Daemen MJAP, Krams R, De Crom R(2006). Atherosclerotic lesion size and vulnerability are determined by patterns of fluid shear stress. Circulation vol. 113, (23) 2744-2753.
10.1161/CIRCULATIONAHA.105.590018
Nette RW, Ie EHY, Vletter WB, Krams R, Weimar W, Zietse R(2006). Norepinephrine-induced vasoconstriction results in decreased blood volume in dialysis patients. Nephrology Dialysis Transplantation vol. 21, (5) 1305-1311.
10.1093/ndt/gfk070
Cheng C, Van Haperen R, De Waard M, Van Damme LCA, Tempel D, Hanemaaijer L, Van Cappellen GWA, Bos J et al.(2005). Shear stress affects the intracellular distribution of eNOS: Direct demonstration by a novel in vivo technique. Blood vol. 106, (12) 3691-3698.
10.1182/blood-2005-06-2326
Davies PF, Spaan JA, Krams R(2005). Shear stress biology of the endothelium. Annals of Biomedical Engineering vol. 33, (12 SPEC. ISS.) 1714-1718.
10.1007/s10439-005-8774-0
Ie EHY, Krams R, Vletter WB, Nette RW, Weimar W, Zietse R(2005). Myocardial contractility does not determine the haemodynamic response during dialysis. Nephrology Dialysis Transplantation vol. 20, (11) 2465-2471.
10.1093/ndt/gfi088
Cheng C, Tempel D, van Damme L, van Gaalen K, van Haperen R, Krams R, de Crom R (2005). Angiotensin II induces severe intra-plaque hemorrhages in lesions with a vulnerable plaque phenotype in apoE KO mice. CIRCULATION. vol. 112, U221-U221.
Cheng C, Tempel D, van Damme L, van Haperen R, Krams R, de Crom R (2005). Patterns of fluid shear stress determine Atherosclerotic lesion size and vulnerability. CIRCULATION. vol. 112, U347-U347.
Cheng C, Tempel D, van Haperen R, de Crom R, Krams R (2005). Vulnerable lesions induced by low shear stress are characterized by expression of specific inflammatory chemokines. CIRCULATION. vol. 112, U136-U136.
Krams R, Verheye S, Van Damme LCA, Tempel D, Gourabi BM, Boersma E, Kockx MM, Knaapen MWM et al.(2005). In vivo temperature heterogeneity is associated with plaque regions of increased MMP-9 activity. European Heart Journal vol. 26, (20) 2200-2205.
10.1093/eurheartj/ehi461
Wentzel JJ, Gijsen FJH, Schuurbiers JCH, Krams R, Serruys PW, De Feyter PJ, Slager CJ(2005). Geometry guided data averaging enables the interpretation of shear stress related plaque development in human coronary arteries. Journal of Biomechanics vol. 38, (7) 1551-1555.
10.1016/j.jbiomech.2004.06.022
Segers D, Cheng C, De Crom R, Kirschbaum SWM, Oostlander AE, Helderman F, Van Wamel A, Slager CJ et al.(2005). Monocyte adhesion in atherosclerosis: A biomechanical approach. Vascular Disease Prevention vol. 2, (3) 227-235.
10.2174/1567270054368998
Susa D, de Engel SV, van Damme LCA, Roest HP, Krams R, Ijzermans JNM, de Bruin RWF (2005). Donor pre-treatment with tacrolimus reduces matrix metallo proteinase activity and transplant arteriosclerosis. AMERICAN JOURNAL OF TRANSPLANTATION. vol. 5, 442-443.
Schaar JA, De Korte CL, Mastik F, Van Damme LCA, Krams R, Serruys PW, Van Der Steen AFW(2005). Three-dimensional palpography of human coronary arteries: Ex vivo validation and in-patient evaluation. Herz vol. 30, (2) 125-133.
10.1007/s00059-005-2642-4
Krams R, Bambi G, Guidi F, Helderman F, Van Der Steen AFW, Tortoli P(2005). Effect of vessel curvature on Doppler derived velocity profiles and fluid flow. Ultrasound in Medicine and Biology vol. 31, (5) 663-671.
10.1016/j.ultrasmedbio.2005.01.011
Wentzel JJ, Krams R, Slager CJ(2005). Letter regarding article by Korshunov and Berk, "Strain-dependent vascular remodeling: the 'Glagov phenomenon' is genetically determined". Circulation vol. 111, (9)
10.1161/01.CIR.0000157072.64410.01
Frijlink ME, Goertz DE, Van Damme LCA, Krams R, Van Der Steen AFW (2004). Intravascular Ultrasound Tissue Harmonic Imaging in vivo. Proceedings - IEEE Ultrasonics Symposium. vol. 2, 1118-1121.
10.1109/ULTSYM.2004.1417976
Cheng C, de Waard M, van Haperen R, Tempel D, van der Baan A, Krams R, de Crom R (2004). In vivo induction of low shear stress and oscillatory shear stress causes atherosclerosis. CIRCULATION. vol. 110, 39-39.
Cheng C, De Crom R, Van Haperen R, Helderman F, Gourabi BM, Van Damme LCA, Kirschbaum SW, Slager CJ et al.(2004). The role of shear stress in atherosclerosis: Action through gene expression and inflammation?. Cell Biochemistry and Biophysics vol. 41, (2) 279-294.
10.1385/CBB:41:2:279
Krams R, Ten Cate FJ, Carlier SG, Van Der Steen AFW, Serruys PW(2004). Diastolic coronary vascular reserve: A new index to detect changes in the coronary microcirculation in hypertrophic cardiomyopathy. Journal of the American College of Cardiology vol. 43, (4) 670-677.
10.1016/j.jacc.2003.09.046
Cheng C, van Haperen R, de Waard M, de Crom R, Krams R (2004). In vivo induced changes in shear stress patterns affect the expression and the intracellular localization of endothelial nitric oxide synthase. EUROPEAN HEART JOURNAL. vol. 25, 58-58.
Verheye S, De Meyer GRY, Krams R, Kockx MM, Van Damme LCA, Gourabi BM, Knaapen MWM, Van Langenhove G et al.(2004). Intravascular thermography: Immediate functional and morphological vascular findings. European Heart Journal vol. 25, (2) 158-165.
10.1016/j.ehj.2003.10.023
Krams R, van Damme L, Tempel D, Gourabi BM, van der Steen AF (2003). Shear stress is associated with markers of plaque vulnerability. CIRCULATION. vol. 108, 225-225.
Cheng C, van Haperen R, de Waard M, de Crom R, Krams R (2003). eNOS expression responds to changes in shear stress: Direct demonstration in a novel in vivo mouse model. CIRCULATION. vol. 108, 151-151.
Van Haperen R, Cheng C, Mees BME, Van Deel E, De Waard M, Van Damme LCA, Van Gent T, Van Aken T et al.(2003). Functional expression of endothelial nitric oxide synthase fused to green fluorescent protein in transgenic mice. American Journal of Pathology vol. 163, (4) 1677-1686.
10.1016/S0002-9440(10)63524-9
Diamantopoulos L, Liu X, De Scheerder I, Krams R, Li S, Van Cleemput J, Desmet W, Serruys PW(2003). The effect of reduced blood-flow on the coronary wall temperature: Are significant lesions suitable for intravascular thermography?. European Heart Journal vol. 24, (19) 1788-1795.
10.1016/S0195-668X(03)00440-8
de Feyter PJ, Serruys PW, Nieman K, Mollet N, Cademartiri F, van Geuns RJ, Slager C, van der Steen AFW et al.(2003). Imaging of coronary atherosclerosis and identification of the vulnerable plaque. Neth Heart J vol. 11, (9) 347-358.
Wentzel JJ, Janssen E, Vos J, Schuurbiers JCH, Krams R, Serruys PW, De Feyter PJ, Slager CJ(2003). Extension of increased atherosclerotic wall thickness into high shear stress regions is associated with loss of compensatory remodeling. Circulation vol. 108, (1) 17-23.
10.1161/01.CIR.0000078637.21322.D3
Carlier SG, Van Damme LCA, Blommerde CP, Wentzel JJ, Van Langehove G, Verheye S, Kockx MM, Knaapen MWM et al.(2003). Augmentation of wall shear stress inhibits neointimal hyperplasia after stent implantation: Inhibition through reduction of inflammation?. Circulation vol. 107, (21) 2741-2746.
10.1161/01.CIR.0000066914.95878.6D
Wentzel JJ, Gijsen FJH, Stergiopulos N, Serruys PW, Slager CJ, Krams R(2003). Shear stress, vascular remodeling and neointimal formation. Journal of Biomechanics vol. 36, (5) 681-688.
10.1016/S0021-9290(02)00446-3
Krams R, Van Damme LCA, Blommerde CP, Wentzel JJ, Stager C, Knaapen MWM, Serruys PW (2003). Augmentation of wall shear stress inhibits neo intimal hyperplasia and inflammation after stent implantation. EUROPEAN HEART JOURNAL. vol. 24, 427-427.
10.1016/S0195-668X(03)95236-5
Krams R, Van Damme LCA, Gourabi BM, Tempel D, Slager K, Hussain AK, Cheng C, Serruys PW (2003). High shear stress is predictive for markers of plaque inflammation. EUROPEAN HEART JOURNAL. vol. 24, 418-418.
10.1016/S0195-668X(03)95201-8
Krams R, Segers D, Gourabi BM, Maat W, Cheng C, Van Pelt C, Van Damme LCA, De Feyter P et al.(2003). Inflammation and atherosclerosis: Mechanisms underlying vulnerable plaque. Journal of Interventional Cardiology vol. 16, (2) 107-113.
10.1046/j.1540-8183.2003.08021.x
Gourabi BM, Segers D, Van Damme LCA, Cheng C, Knaapen MWM, Kockx MM, Serruys PW, Krams R (2003). Local macrophage accumulation in atherosclerotic rabbit aortas as determined by a novel three-dimensional histology technique. EUROPEAN HEART JOURNAL. vol. 24, 337-337.
10.1016/S0195-668X(03)94898-6
Krams R, Van Damme LCA, Verheye S, Gourabi BM, Strijder C, Pasterkamp G, Knaapen MWM, Serruys PW (2003). Plaque temperature heterogeneity is associated with macrophage accumulation and metalloproteinase activity. EUROPEAN HEART JOURNAL. vol. 24, 153-153.
10.1016/S0195-668X(03)94221-7
de Korte CL, Schaar JA, Mastik F, van Damme LCA, Krams R, Serruys PW, van der Steen AFW (2002). Vulnerable plaque detection with 3-dimensional palpography. CIRCULATION. vol. 106, 1-2.
Ie EHY, Krams R, Vletter WB, ten Cate FJ, Nette RW, Weimar W, Zietse R (2002). Reduced end-systolic elastance indicating poor left ventricular contractility in hemodialysis patients. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. vol. 13, 213A-213A.
Thury A, Wentzel JJ, Vinke RVH, Gijsen FJH, Schuurbiers JCH, Krams R, de Feyter PJ, Serruys PW et al.(2002). Focal in-stent restenosis near step-up - Roles of low and oscillating shear stress?. CIRCULATION vol. 105, (23) E185-E187.
10.1161/01.CIR.0000018282.32332.13
Wentzel JJ, Janssen EH, Krams R, Schuurbiers JCH, van der Giessen WJ, Serruys PW, de Feyter PJ, Slager CJ (2002). Determination of shear stress in patients confirms that lumen preservation in atherosclerosis is associated with shear stress regulation. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 39, 217A-217A.
Trines SAIP, Smits CAG, Van der Moer J, Slager CJ, Verdouw PD, Krams R(2002). Calcium sensitizer EMD 57033, but not the β<inf>1</inf>-adrenoreceptor agonist dobutamine, increases mechanical efficiency in stunned myocardium. Journal of Cardiovascular Pharmacology vol. 39, (1) 61-72.
10.1097/00005344-200201000-00008
Thury A, Van Langenhove G, Carlier SG, Albertal M, Kozuma K, Regar E, Sianos G, Wentzel JJ et al.(2002). High shear stress after successful balloon angioplasty is associated with restenosis and target lesion revascularization. American Heart Journal vol. 144, (1) 136-143.
10.1067/mhj.2002.123110
Thury A, Wentzel JJ, Vinke RVH, Gijsen FJH, Schuurbiers JCH, Krams R, de Feyter PJ, Serruys PW et al.(2002). Images in cardiovascular medicine. Focal in-stent restenosis near step-up: roles of low and oscillating shear stress?. Circulation vol. 105, (23)
10.1161/01.cir.0000018282.32332.13
Wentzel JJ, Janssen E, Vos J, Schuurbiers JCH, Krams R, Serruys PW, de Feyter PJ, Slager CJ (2002). The relationship between wall thickness and shear stress in coronary arteries of patients. EUROPEAN HEART JOURNAL. vol. 23, 415-415.
Carlier SG, van Damme LC, Blommerde CP, Van Langenhove G, Wentzel JJ, van der Giessen WJ, Verdouw PD, Krams R et al. (2001). An increased wall shear stress inhibits neointimal hyperplasia after stent implantation: preliminary in vivo experience of the ARED flow divider in a rabbit model of restenosis. EUROPEAN HEART JOURNAL. vol. 22, 278-278.
Krams R, van Damme LCA, Wentzel JJ, De Crom R, Haperen R, Van Aken T (2001). Functional assessment of eNOS transgenesis in mice aortas. EUROPEAN HEART JOURNAL. vol. 22, 60-60.
Trines SAIP, Slager CJ, Onderwater TAM, Lamers JMJ, Verdouw PD, Krams R (2001). Oxygen wastage of stunned myocardium in vivo is due to an increased oxygen cost of contractility and a decreased myofibrillar efficiency. EUROPEAN HEART JOURNAL. vol. 22, 516-516.
Willemsen MJJMF, Duncker DJ, Krams R, Dijkman MA, Lamberts RR, Sipkema P, Westerhof N(2001). Decrease in coronary vascular volume in systole augments cardiac contraction. American Journal of Physiology - Heart and Circulatory Physiology vol. 281, (2 50-2)
Willemsen MJ, Duncker DJ, Krams R, Dijkman MA, Lamberts RR, Sipkema P, Westerhof N(2001). Decrease in coronary vascular volume in systole augments cardiac contraction. Am J Physiol Heart Circ Physiol vol. 281, (2) H731-H737.
10.1152/ajpheart.2001.281.2.H731
Wentzel JJ, Kloet J, Andhyiswara I, Oomen JAF, Schuurbiers JCH, De Smet BJGL, Post MJ, De Kleijn D et al.(2001). Shear-stress and wall-stress regulation of vascular remodeling after balloon angioplasty: Effect of matrix metalloproteinase inhibition. Circulation vol. 104, (1) 91-96.
10.1161/01.CIR.104.1.91
Trines SAIP, Slager CJ, Onderwater TAM, Lamers JMJ, Verdouw PD, Krams R(2001). Oxygen wastage of stunned myocardium in vivo is due to an increased oxygen cost of contractility and a decreased myofibrillar efficiency. Cardiovascular Research vol. 51, (1) 122-130.
10.1016/S0008-6363(01)00277-2
Wentzel JJ, Krams R, Schuurbiers JCH, Oomen JA, Kloet J, Van Der Giessen WJ, Serruys PW, Slager CJ(2001). Relationship between neointimal thickness and shear stress after wallstent implantation in human coronary arteries. Circulation vol. 103, (13) 1740-1745.
10.1161/01.CIR.103.13.1740
Thury A, van Langenhove G, Carlier SG, Albertal M, Kozuma K, Regar E, Wentzel JJ, Krams R et al. (2001). High shear stress after successful balloon angioplasty is associated with restenosis and target lesion revascularization. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 37, 16A-17A.
Thury A, Wentzel JJ, Janssen EH, Krams R, Oomen JA, Schuurbiers JCH, Ligthart JMR, Serruys PW et al. (2001). Novel method for in vivo calculation of absolute sheer stress at any location of a stented human coronary artery. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. vol. 37, 298A-299A.
Wolters BJBM, Slager CJ, Gijsen FJH, Wentzel JJ, Krams R, Van De Vosse FN (2001). On the numerical analysis of coronary artery wall shear stress. Computers in Cardiology. 169-172.
10.1109/CIC.2001.977618
Thury A, Wentzel JJ, Schuurbiers JC, Ligthart JM, Krams R, de Feyter PJ, Serruys PW, Slager CJ(2001). Prominent role of tensile stress in propagation of a dissection after coronary stenting: computational fluid dynamic analysis on true 3d-reconstructed segment. Circulation vol. 104, (11)
10.1161/hc3601.095216
Trines SAIP, Slager CJ, Van Der Moer J, Verdouw PD, Krams R(2000). Efficiency of energy transfer, but not external work, is maximized in stunned myocardium. American Journal of Physiology - Heart and Circulatory Physiology vol. 279, (3 48-3)
Trines SA, Slager CJ, van der Moer J, Verdouw PD, Krams R(2000). Efficiency of energy transfer, but not external work, is maximized in stunned myocardium. Am J Physiol Heart Circ Physiol vol. 279, (3) H1264-H1273.
10.1152/ajpheart.2000.279.3.H1264
De Zeeuw S, Trines SAIP, Krams R, Duncker DJ, Verdouw PD(2000). In vivo evidence that EMD 57033 restores myocardial responsiveness to intracoronary Ca<sup>2+</sup> in stunned myocardium. European Journal of Pharmacology vol. 403, (1-2) 99-109.
10.1016/S0014-2999(00)00513-6
Slager CJ, Wentzel JJ, Schuurbiers JCH, Oomen JAF, Kloet J, Krams R, Von Birgelen C, Van Der Giessen WJ et al.(2000). True 3-dimensional reconstruction of coronary arteries in patients by fusion of angiography and IVUS (ANGUS) and its quantitative validation. Circulation vol. 102, (5) 511-516.
10.1161/01.CIR.102.5.511
Bom N, De Korte CL, Wentzel JJ, Krams R, Carlier SG, Van Der Steen AWF, Slager CJ, Roelandt JRTC(2000). Quantification of plaque volume, shear stress on the endothelium, and mechanical properties of the arterial wall with intravascular ultrasound imaging. Zeitschrift fur Kardiologie vol. 89, (SUPPL. 2)
10.1007/s003920070108
De Zeeuw S, Trines SAIP, Krams R, Verdouw PD, Duncker DJ(2000). Cardiovascular profile of the calcium sensitizer EMD 57033 in open-chest anaesthetized pigs with regionally stunned myocardium. British Journal of Pharmacology vol. 129, (7) 1413-1422.
10.1038/sj.bjp.0703231
Wentzel JJ, Whelan D, Van Der Giessen WJ, Van Beusekom HMM, Andhyiswara I, Serruys PW, Slager CJ, Krams R(2000). Coronary stent implantation changes 3-D vessel geometry and 3-D shear stress distribution. Journal of Biomechanics vol. 33, (10) 1287-1295.
10.1016/S0021-9290(00)00066-X
Willemsen MJJMF, Duncker DJ, Krams R, Dijkman MA, Sipkema P, Westerhof N (2000). Coronary systolic flow impediment is functional in cardiac contraction. EUROPEAN HEART JOURNAL. vol. 21, 667-667.
Van Langenhove G, Wentzel JJ, Krams R, Slager CJ, Hamburger JN, Serruys PW(2000). Helical velocity patterns in a human coronary artery: a three-dimensional computational fluid dynamic reconstruction showing the relation with local wall thickness. Circulation vol. 102, (3)
10.1161/01.cir.102.3.e22
Soei LK, De Zeeuw S, Krams R, Duncker DJ, Verdouw PD(1999). Ca<sup>2+</sup> sensitization and diastolic function of normal and stunned porcine myocardium. European Journal of Pharmacology vol. 386, (1) 55-67.
10.1016/S0014-2999(99)00684-6
Oomen JA, Trines SAIP, Vermeulen WB, Krams R, Schuurbiers JCH, Vletter WB, Roelandt JRTC, Slager CJ (1999). Towards assessment of regional wall stress of the left ventricle using 3D ultrasound imaging. Computers in Cardiology. 129-132.
10.1109/CIC.1999.825923
Trines SA, Van der Moer J, Krams R, Slager CJ, Van Meegen JR, Verdouw PD (1999). External work recruitment can be restored in stunned myocardium without increasing oxygen consumption using EMD 57033, a calcium sensitizer. CIRCULATION. vol. 100, 8-8.
Wentzel JJ, Kloet J, Krams R, Serruys PW, Slager CJ (1999). The relationship between neo intimal thickness and shear stress after wallstent implantation in human coronary arteries at 6 months follow up. CIRCULATION. vol. 100, 727-727.
Krams R, Wentzel JJ, Cespedes I, Vinke R, Carlier S, Van Der Steen AFW, Lancee CT, Slager CJ(1999). Effect of catheter placement on 3-D velocity profiles in curved tubes resembling the human coronary system. Ultrasound in Medicine and Biology vol. 25, (5) 803-810.
10.1016/S0301-5629(99)00018-6
van der Steen AFW, Cespedes EI, de Korte CL, Carlier SG, Li W, Mastik F, Lancee CT, Borsboom J et al. (1998). Novel developments in intravascular imaging. Proceedings of the IEEE Ultrasonics Symposium. vol. 2, 1733-1742.
Osterop AP, Kofflard MJ, Sandkuijl LA, ten Cate FJ, Krams R, Schalekamp MA, Danser AH(1998). AT1 receptor A/C1166 polymorphism contributes to cardiac hypertrophy in subjects with hypertrophic cardiomyopathy. Hypertension vol. 32, (5) 825-830.
10.1161/01.hyp.32.5.825
Stager CJ, Wentzel JJ, Schuurbiers JC, Oomen JA, Krams R, Achterberg H, Kloet J, deFeyter PJ (1998). True 3-D reconstruction of coronary arteries in patients shows accurate correspondence between x-ray and IVUS derived dimensions. CIRCULATION. vol. 98, 508-509.
Krams R, Kofflard MJM, Duncker DJ, Von Birgelen C, Carlier S, Kliffen M, Ten Cate FJ, Serruys PW(1998). Decreased coronary flow reserve in hypertrophic cardiomyopathy is related to remodeling of the coronary microcirculation. Circulation vol. 97, (3) 230-233.
10.1161/01.CIR.97.3.230
Osterop APRM, Kofflard MJM, Sandkuijl LA, Ten Cate FJ, Krams R, Schalekamp MADH, Danser AHJ(1998). AT<inf>1</inf> receptor A/C<sup>1166</sup> polymorphism contributes to cardiac hypertrophy in subjects with hypertrophic cardiomyopathy. Hypertension vol. 32, (5) 825-830.
10.1161/01.HYP.32.5.825
Krams R, Wentzel JJ, Oomen JA, Schuurbiers JC, Andhyiswara I, Kloet J, Post M, de Smet B et al.(1998). Shear stress in atherosclerosis, and vascular remodelling. Seminars in interventional cardiology : SIIC vol. 3, (1) 39-44.
Fan D, Soei LK, Stubenitsky R, Boersma E, Duncker DJ, Verdouw PD, Krams R(1997). Contribution of asynchrony and nonuniformity to mechanical interaction in normal and stunned myocardium. American Journal of Physiology - Heart and Circulatory Physiology vol. 273, (5 42-5)
Dongsheng FA, Kie Soei LO, Stubenitsky R, Boersma E, Duncker DJ, Verdouw PD, Krams ROB(1997). Contribution of asynchrony and nonuniformity to mechanical interaction in normal and stunned myocardium. American Journal of Physiology - Heart and Circulatory Physiology vol. 42, (5)
Wentzel JJ, Krams R, van der Steen AFW, Li W, Cespedes EI, Bom N, Slager CJ (1997). Disturbance of 3D velocity profiles induced by an IVUS catheter: Evaluation with computational fluid dynamics. Computers in Cardiology. 597-600.
10.1109/CIC.1997.648024
Krams R, Wentzel JJ, Oomen J, Schuurbier J, Vinke R, Slager CJ (1997). Evidence for a pivotal role of shear stress on the endothelium in human atherosclerosis. Endothelium: Journal of Endothelial Cell Research. vol. 5,
Fan DS, Soei LK, Stubenitsky R, Boersma E, Duncker DJ, Verdouw PD, Krams R(1997). Contribution of asynchrony and nonuniformity to mechanical interaction in normal and stunned myocardium. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY vol. 273, (5) H2146-H2154.
Fan D, Soei LK, Stubenitsky R, Boersma E, Duncker DJ, Verdouw PD, Krams R(1997). Contribution of asynchrony and nonuniformity to mechanical interaction in normal and stunned myocardium. Am J Physiol vol. 273, (5) H2146-H2154.
10.1152/ajpheart.1997.273.5.H2146
deZeeuw S, Soei L, vanMeegen JR, Trines SA, Krams R, Duncker DJ, Verdouw PD (1997). Recovery of systolic function of stunned myocardium by the Ca2+-sensitizer EMD 57033 is not accompanied by impairment of diastolic function. CIRCULATION. vol. 96, 1109-1109.
Wentzel JJ, Krams R, vanBeusekom HMN, Whelan DM, vanderGeissen WJ, Krabbendam SC, Andhyiswara I, Tjien ATJ et al. (1997). Stent implantation causes alterations in 3D-geometry and 3D-shear stress distribution at the endothelium of coronary arteries. CIRCULATION. vol. 96, 2349-2349.
Van Blankenstein JH, Slager CJ, Soei LK, Boersma H, Stijnen T, Schuurbiers JCH, Krams R, Lachmann B et al.(1997). Cardiac depression after experimental air embolism in pigs: Role of addition of a surface-active agent. Cardiovascular Research vol. 34, (3) 473-482.
10.1016/S0008-6363(97)00063-1
Van Der Steen AFW, Rijsterborgh H, Lancée CT, Mastik F, Krams R, Verdouw PD, Roelandt JRTC, Bom N(1997). Influence of data processing on cyclic variation of integrated backscatter and wall thickness in stunned porcine myocardium. Ultrasound in Medicine and Biology vol. 23, (3) 405-414.
10.1016/S0301-5629(96)00227-X
Krams R, Wentzel JJ, Oomen JAF, Vinke R, Schuurbiers JCH, De Feyter PJ, Serruys PW, Slager CJ(1997). Evaluation of endothelial shear stress and 3D geometry as factors determining the development of atherosclerosis and remodeling in human coronary arteries in vivo: Combining 3D reconstruction from angiography and IVUS (ANGUS) with computational fluid dynamics. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 17, (10) 2061-2065.
10.1161/01.ATV.17.10.2061
Slager CJ, Wentzel JJ, Oomen JA, Schuurbiers JC, Krams R, von Birgelen C, Tjon A, Serruys PW et al.(1997). True reconstruction of vessel geometry from combined X-ray angiographic and intracoronary ultrasound data. Seminars in interventional cardiology : SIIC vol. 2, (1) 43-47.
Wentzel JJ, Krams R, Oomen JAF, Schuurbiers JCH, Vinke R, Bom N, Slager CJ (1996). Applying computational fluid dynamics to a spatially correct 3D reconstruction of a coronary arterial segment in the individual patient. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 3, 1310-1311.
Soei LK, Krams R, Duncker DJ, Verdouw PD (1996). The ca<sup>2+</sup> sensmser emd 60263 only impairs diastolic function of stunned myocardium at high doses in anesthetized swine. FASEB Journal. vol. 10,
Bezstarosti K, Soei LK, Krams R, Ten Cate FJ, Verdouw PD, Lamers JMJ(1996). The effect of a thiadiazinone derived Ca<sup>2+</sup> sensitizer on the responsiveness of Mg<sup>2+</sup>-ATPase to Ca<sup>2+</sup> in myofibrils isolated from stunned and nonstunned porcine and human myocardium. Biochemical Pharmacology vol. 51, (9) 1211-1220.
10.1016/0006-2952(96)00083-4
Rijsterborgh H, Van Der Steen AFW, Krams R, Mastik F, Lancée CT, Verdouw PD, Roelandt JRTC, Bom N(1996). The relationship between myocardial integrated backscatter, perfusion pressure and wall thickness during isovolumic contraction: An isolated pig heart study. Ultrasound in Medicine and Biology vol. 22, (1) 43-52.
10.1016/0301-5629(95)02030-6
Laban M, Oomen JA, Slager CJ, Wentzel JJ, Krams R, Schuurbiers JCH, den Boer A, von Birgelen C et al. (1995). ANGUS: a new approach to three-dimensional reconstruction of coronary vessels by combined use of angiography and intravascular ultrasound. Computers in Cardiology. 325-328.
10.1109/CIC.1995.482638
VONBIRGELEN C, KRAMS R, GIL R, TENGATE FJ, DIMARIO C (1995). HOW SHOULD WE EVALUATE THE VASODILATORY CAPACITY OF CORONARY RESISTANCE VESSELS IN PATIENTS WITH ASYMMETRIC HYPERTROPHIC CARDIOMYOPATHY. CIRCULATION. vol. 92, 960-960.
VONBIRGELEN C, KRAMS R, DIMARIO C, GIL R, KOFFLARD M, TENCATE FJ, REIMERS B, SLAGER CJ et al. (1995). SYSTEMATIC STUDY OF FLOW VELOCITY PROFILES IN EPICARDIAL CORONARY-ARTERIES OF PATIENTS WITH HYPERTROPHIC CARDIOMYOPATHY AND SUBAORTIC OUTFLOW GRADIENT. CIRCULATION. vol. 92, 1549-1549.
Wilson RA, di Mario C, Krams R, Soei LK, Wenguang L, Laird AC, The SHK, Gussenhoven E et al.(1995). In Vivo Measurement of Regional Large Artery Compliance by Intravascular Ultrasound Under Pentobarbital Anesthesia. Angiology vol. 46, (6) 481-488.
10.1177/000331979504600604
Fan D, Soei LK, Sassen LMA, Krams R, Verdouw PD(1995). Mechanical efficiency of stunned myocardium is modulated by increased afterload dependency. Cardiovascular Research vol. 29, (3) 428-437.
10.1016/0008-6363(96)88602-0
Di Mario C, Gil R, Krams R, De Feyter PJ, Serruys W(1995). New invasive techniques of assessment of the physiological significance of coronary stenoses in humans. European Heart Journal vol. 16, (SUPPL. I) 104-114.
10.1093/eurheartj/16.suppl_i.104
KRAMS R, JANSSEN M, VANDERLEE C, VANMEEGEN J, DEJONG JW, SLAGER CJ, VERDOUW PD(1994). LOSS OF ELASTIC RECOIL IN POSTISCHEMIC MYOCARDIUM INDUCES RIGHTWARD SHIFT OF THE SYSTOLIC PRESSURE-VOLUME RELATIONSHIP. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY vol. 267, (4) H1557-H1564.
Krams R, Janssen M, Van der Lee C, Van Meegen J, De Jong JW, Slager CJ, Verdouw PD(1994). Loss of elastic recoil in postischemic myocardium induces rightward shift of the systolic pressure-volume relationship. Am J Physiol vol. 267, (4 Pt 2) H1557-H1564.
10.1152/ajpheart.1994.267.4.H1557
FAN DS, KRAMS R, SOEI LK, SASSEN LMA, VERDOUW PD (1994). REVERSAL OF INCREASED LOAD-DEPENDENCY OF EFFICIENCY OF ENERGY-CONVERSION IN STUNNED MYOCARDIUM BY INCREASING THE CA2+ SENSITIVITY. CIRCULATION. vol. 90, 645-645.
FAN DS, KRAMS R, SOEI LK, SASSEN LMA, VERDOUW PD (1994). VARIABILITY IN OXYGEN-CONSUMPTION MEASUREMENTS DURING MYOCARDIAL STUNNING CAN BE EXPLAINED BY A PRONOUNCED AFTERLOAD DEPENDENCY OF SEGMENT LENGTH SHORTENING, EXTERNAL WORK AND MECHANICAL EFFICIENCY. CIRCULATION. vol. 90, 645-645.
Fan D, Soei LK, Sassen LM, Krams R, Verdouw PD(1994). Mechanical efficiency of stunned myocardium is modulated by increased afterload dependency. Cardiovascular Research vol. 28, (9) 428-437.
10.1016/S0008-6363(96)88602-0
Loe Kie Soei, Sassen LMA, Dong Sheng Fan, Van Veen T, Krams R, Verdouw PD(1994). Myofibrillar Ca<sup>2+</sup> sensitization predominantly enhances function and mechanical efficiency of stunned myocardium. Circulation vol. 90, (2) 959-969.
10.1161/01.cir.90.2.959
Fan D, Kie Soei L, Sassen LMA, Krams R, Hendrik E, Verdouw PD(1994). On the Reversal of Myocardial Stunning: A Role for Ca2+-Sensitizers. Ann N Y Acad Sci vol. 723, (1) 364-367.
10.1111/j.1749-6632.1994.tb36748.x
Fan D, Sassen LMA, Trines SAIP, Soei LK, Krams R, Verdouw PD(1994). Increasing the Ca<sup>++</sup> sensitivity reverses the increased afterload dependency of external work and the efficiency of energy conversion of stunned myocardium. Applied Cardiopulmonary Pathophysiology vol. 5, (2) 63-72.
Krams R, Janssen M, Van der Lee C, Van Meegen J, De Jong JW, Slager CJ, Verdouw PD(1994). Loss of elastic recoil in postischemic myocardium induces rightward shift of the systolic pressure-volume relationship. American Journal of Physiology - Heart and Circulatory Physiology vol. 267, (4 36-4)
10.1152/ajpheart.1994.267.4.h1557
FAN D, KIE SOEI L, SASSEN LMA, KRAMS R, HENDRIK E, VERDOUW PD(1994). On the Reversal of Myocardial Stunning: A Role for Ca<sup>2+</sup>‐Sensitizers. Annals of the New York Academy of Sciences vol. 723, (1) 364-367.
10.1111/j.1749-6632.1994.tb36748.x
Di Mario C, Krams R, Gil R, Serruys PW(1994). Slope of the instantaneous hyperemic diastolic coronary flow velocity- pressure relation: A new index for assessment of the physiological significance of coronary stenosis in humans. Circulation vol. 90, (3) 1215-1224.
10.1161/01.CIR.90.3.1215
KRAMS R, SOEI LK, MCFALLS EO, PRINS EAW, SASSEN LMA, VERDOUW PD(1993). END-SYSTOLIC PRESSURE LENGTH RELATIONS OF STUNNED RIGHT-AND-LEFT-VENTRICLES AFTER INOTROPIC STIMULATION. AMERICAN JOURNAL OF PHYSIOLOGY vol. 265, (6) H2099-H2109.
Krams R, Loe Kie Soei, McFalls EO, Prins EAW, Sassen LMA, Verdouw PD(1993). End-systolic pressure length relations of stunned right and left ventricles after inotropic stimulation. American Journal of Physiology - Heart and Circulatory Physiology vol. 265, (6 34-6)
Krams R, Soei LK, McFalls EO, Winkler Prins EA, Sassen LM, Verdouw PD(1993). End-systolic pressure length relations of stunned right and left ventricles after inotropic stimulation. Am J Physiol vol. 265, (6 Pt 2) H2099-H2109.
10.1152/ajpheart.1993.265.6.H2099
Bruining N, Krams R, Passchier H, Meij S, de Feijter P, Keane D (1993). Modular hard and software system for the analysis of cardiac signals: application to real time pressure-volume loops. Computers in Cardiology. 161-164.
Koning MMG, Krams R, Xiao CS, van Meegen JR, Bezstarosti K, Lamers JMJ, Verdouw PD(1993). Intracoronary trimetazidine does not improve recovery of regional function in a porcine model of repeated ischemia. Cardiovascular Drugs and Therapy vol. 7, (5) 801-807.
10.1007/BF00878934
DIMARIO C, KRAMS R, BALK A, VERDOUW PD, ROELANDT J (1993). CAN THE ZERO-FLOW PRESSURE BE EXTRAPOLATED FROM THE FLOW VELOCITY-PRESSURE RELATION DURING LONG DIASTOLIC PAUSES IN HUMANS. CIRCULATION. vol. 88, 204-204.
McFalls EO, Duncker DJ, Sassen LMA, Krams R, Man in't Veld AJ, Ruffolo RR, Verdouw PD(1993). Altered coronary flow reserve in the hypertrophied heart: Implications for therapy. Journal of Human Hypertension vol. 7, (SUPPL. 1)
Krams R, Duncker DJ, McFalls EO, Hogendoorn A, Verdouw PD(1993). Dobutamine restores the reduced efficiency of energy transfer from total mechanical work to external mechanical work in stunned porcine myocardium. Cardiovascular Research vol. 27, (5) 740-747.
Duncker DJ, Sassen LMA, Bartels GL, Van Meegen JR, McFalls EO, Krams R, Bezstarosti K, Lamers JMJ et al.(1993). L-propionylcarnitine does not affect myocardial metabolic or functional response to chronotropic and inotropic stimulation after repetitive ischemia in anesthetized pigs. Journal of Cardiovascular Pharmacology vol. 22, (3) 488-498.
10.1097/00005344-199309000-00022
MCFALLS EO, DUNCKER DJ, KRAMS R, SASSEN LMA, HOOGENDOORN A, VERDOUW PD(1992). RECRUITMENT OF MYOCARDIAL WORK AND METABOLISM IN REGIONALLY STUNNED PORCINE MYOCARDIUM. AMERICAN JOURNAL OF PHYSIOLOGY vol. 263, (6) H1724-H1731.
McFalls EO, Duncker DJ, Krams R, Sassen LMA, Hoogendoorn A, Verdouw PD(1992). Recruitment of myocardial work and metabolism in regionally stunned porcine myocardium. American Journal of Physiology - Heart and Circulatory Physiology vol. 263, (6 32-6)
McFalls EO, Duncker DJ, Krams R, Sassen LM, Hoogendoorn A, Verdouw PD(1992). Recruitment of myocardial work and metabolism in regionally stunned porcine myocardium. Am J Physiol vol. 263, (6 Pt 2) H1724-H1731.
10.1152/ajpheart.1992.263.6.H1724
Sassen LMA, Duncker DJ, Hogendoorn A, McFalls EO, Krams R, Bezstarosti K, Lamers JMJ, Verdouw PD(1992). L-propionylcarnitine and myocardial performance in stunned porcine myocardium. Molecular and Cellular Biochemistry vol. 116, (1-2) 147-153.
10.1007/BF01270582
MCFALLS EO, KRAMS R, DUNCKER DJ, SASSEN LMA, HOOGENDOORN A, VERDOUW PD (1992). RECRUITMENT OF REGIONAL EXTERNAL WORK AND OXYGEN-CONSUMPTION IN STUNNED PORCINE MYOCARDIUM. CIRCULATION. vol. 86, 613-613.
DUNCKER DJ, MCFALLS EO, KRAMS R, VERDOUW PD(1992). PRESSURE-MAXIMAL CORONARY FLOW RELATIONSHIP IN REGIONALLY STUNNED PORCINE MYOCARDIUM. AMERICAN JOURNAL OF PHYSIOLOGY vol. 262, (6) H1744-H1751.
Duncker DJ, McFalls EO, Krams R, Verdouw PD(1992). Pressure-maximal coronary flow relationship in regionally stunned porcine myocardium. Am J Physiol vol. 262, (6 Pt 2) H1744-H1751.
10.1152/ajpheart.1992.262.6.H1744
Duncker DJ, McFalls EO, Krams R, Verdouw PD(1992). Pressure-maximal coronary flow relationship in regionally stunned porcine myocardium. American Journal of Physiology - Heart and Circulatory Physiology vol. 262, (6 31-6)
McFalls EO, Duncker DJ, Krams R, Ward H, Gornick C, Verdouw PD(1991). Endothelium dependent vasodilatation following brief ischaemia and reperfusion in anaesthetised swine. Cardiovascular Research vol. 25, (8) 659-665.
10.1093/cvr/25.8.659
Krams R, McFalls E, van der Giessen WJ, Serruys PW, Verdoun PD, Roelandt J(1991). Does intravenous milrinone have a direct effect on diastolic function?. Am Heart J vol. 121, (6 Pt 2) 1951-1955.
10.1016/0002-8703(91)90831-2
Krams R, McFalls E, van der Giessen WJ, Serruys PW, Verdoun PD, Roelandt J (1991). Does intravenous milrinone have a direct effect on diastolic function?. American Heart Journal. vol. 121, 1951-1955.
10.1016/0002-8703(91)90831-2
Mcfalls EO, Duncker DJ, Krams R, Ward H, Gornick C, Verdouw PD(1991). Endothelium dependent vasodilatation following brief ischaemia and reperfusion in anaesthetised swine. Cardiovascular Research vol. 25, (8) 659-665.
10.1093/cvr/25.8.659
KRAMS R, MCFALLS E, VANDERGIESSEN WJ, SERRUYS PW, ROELANDT J (1991). THE EFFECT OF MILRINONE ON DIASTOLIC FUNCTION - DIRECT OR INDIRECT EFFECT. ACUTE THERAPY OF HEART FAILURE. vol. 2, 35-42.
RESAR J, LIVINGSTON JZ, HALPERIN HR, SIPKEMA P, KRAMS R, YIN FCP(1990). EFFECT OF WALL STRETCH ON CORONARY HEMODYNAMICS IN ISOLATED CANINE INTERVENTRICULAR SEPTUM. AMERICAN JOURNAL OF PHYSIOLOGY vol. 259, (6) H1869-H1880.
Resar J, Livingston JZ, Halperin HR, Sipkema P, Krams R, Yin FC(1990). Effect of wall stretch on coronary hemodynamics in isolated canine interventricular septum. Am J Physiol vol. 259, (6 Pt 2) H1869-H1880.
10.1152/ajpheart.1990.259.6.H1869
WESTERHOF N, SIPKEMA P, KRAMS R(1990). MYOCARDIAL MODULATION OF CORONARY CIRCULATION - REPLY. AMERICAN JOURNAL OF PHYSIOLOGY vol. 259, (6) H1936-H1937.
Westerhof N, Sipkema P, Krams R(1990). Myocardial modulation of coronary circulation Reply). American Journal of Physiology - Heart and Circulatory Physiology vol. 259, (6 28-6)
KRAMS R, SIPKEMA P, WESTERHOF N(1990). CORONARY OSCILLATORY FLOW AMPLITUDE IS MORE AFFECTED BY PERFUSION-PRESSURE THAN VENTRICULAR PRESSURE. AMERICAN JOURNAL OF PHYSIOLOGY vol. 258, (6) H1889-H1898.
Krams R, Sipkema P, Westerhof N(1990). Coronary oscillatory flow amplitude is more affected by perfusion pressure than ventricular pressure. Am J Physiol vol. 258, (6 Pt 2) H1889-H1898.
10.1152/ajpheart.1990.258.6.H1889
Krams R, Sipkema P, Westerhof N(1990). Coronary oscillatory flow amplitude is more affected by perfusion pressure than ventricular pressure. American Journal of Physiology - Heart and Circulatory Physiology vol. 258, (6 27-6)
10.1152/ajpheart.1990.258.6.h1889
Resar J, Livingston JZ, Halperin HR, Sipkema P, Krams R, Yin FCP(1990). Effect of wall stretch on coronary hemodynamics in isolated canine interventricular septum. American Journal of Physiology - Heart and Circulatory Physiology vol. 259, (6 28-6)
10.1152/ajpheart.1990.259.6.h1869
Krams R, Sipkema P, Zegers J, Westerhof N(1989). Contractility is the main determinant of coronary systolic flow impediment. American Journal of Physiology - Heart and Circulatory Physiology vol. 257, (6)
Krams R, Sipkema P, Zegers J, Westerhof N(1989). Contractility is the main determinant of coronary systolic flow impediment. Am J Physiol vol. 257, (6 Pt 2) H1936-H1944.
10.1152/ajpheart.1989.257.6.H1936
Krams R, Sipkema P, Westerhof N(1989). Varying elastance concept may explain coronary systolic flow impediment. Am J Physiol vol. 257, (5 Pt 2) H1471-H1479.
10.1152/ajpheart.1989.257.5.H1471
Krams R, van Haelst ACTA, Sipkema P, Westerhof N(1989). Can coronary systolic-diastolic flow differences be predicted by left ventricular pressure or time-varying intramyocardial elastance?. Basic Research in Cardiology vol. 84, (2) 149-159.
10.1007/BF01907924
Krams R, Sipkema P, Westerhof N(1989). Varying elastance concept may explain coronary systolic flow impediment. American Journal of Physiology - Heart and Circulatory Physiology vol. 257, (5)
Van Dijk LC, Krams R, Sipkema P, Westerhof N(1988). Changes in coronary pressure-flow relation after transition from blood to Tyrode perfusion. Am J Physiol vol. 255, (3 Pt 2) H476-H482.
10.1152/ajpheart.1988.255.3.H476
YIN F, SIPKEMA P, KRAMS R, STRUMPF R, RESAR J (1988). EFFECTS OF STRETCH ON THE PRESSURE-FLOW RELATION OF THE ISOLATED ARRESTED DOG SEPTUM. FASEB JOURNAL. vol. 2, A302-A302.
SIPKEMA P, KRAMS R, WESTERHOF N (1988). SYSTOLIC CORONARY FLOW IMPEDIMENT EXPLAINED ON BASIS OF THE TIME-VARYING ELASTANCE CONCEPT. FASEB JOURNAL. vol. 2, A929-A929.
Van Dijk LC, Krams R, Sipkema P, Westerhof N(1988). Changes in coronary pressure-flow relation after transition from blood to Tyrode perfusion. American Journal of Physiology - Heart and Circulatory Physiology vol. 255, (3)
Westerhof N, Krams R, Canty JM(1986). Comments on 'pressure and tone dependence of coronary diastolic input impedance and capacitance'. American Journal of Physiology - Heart and Circulatory Physiology vol. 250, (2)
Westerhof N, Krams R(1986). Comments on "Pressure and tone dependence of coronary diastolic input impedance and capacitance". Am J Physiol vol. 250, (2 Pt 2) H330-H331.
10.1152/ajpheart.1986.250.2.H330
WESTERHOF N, KRAMS R(1986). PRESSURE AND TONE DEPENDENCE OF CORONARY DIASTOLIC INPUT IMPEDANCE AND CAPACITANCE - COMMENT. AMERICAN JOURNAL OF PHYSIOLOGY vol. 250, (2) H330-H330.
KRAMS R, SIPKEMA P, WESTERHOF N (1985). DOES LEFT-VENTRICULAR PRESSURE INFLUENCE THE CORONARY PRESSURE-FLOW RELATION IN THE CAT. JOURNAL OF PHYSIOLOGY-LONDON. vol. 366, P42-P42.
Sipkema P, Burattini R, van Haelst ACTA, Krams R, Westerhof N (1984). EFFECTS OF CARDIAC CONTRACTION ON CORONARY FLOW. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings.
Borgdorff P, Braakman R, van Haelst AC, van Huis GA, de Jong JP, Krams R, Langewouters GJ, Sipkema P et al.(1984). "Consistent parallel relationships among myocardial oxygen consumption, coronary blood flow, and pericardial infusate adenosine concentration with various interventions and beta-blockade in the dog". Circulation research vol. 54, (3)
10.1161/01.RES.54.3.348
Westerhof N, Krams R, Van Haelst ACTA, Sipkema P (1984). Can left ventricular pressure explain coronary flow impediment?. Federation Proceedings. vol. 43,
BRAAKMAN R, VANDERHORN GJ, VONHUIS GA, KRAMS R, LANGEWOUTERS GJ, SIPKEMA P, WESTERHOF N(1982). THE EFFECTS OF THE CORONARY CAPACITANCE ON THE INTERPRETATION OF DIASTOLIC PRESSURE-FLOW RELATIONSHIPS - COMMENTS. CIRCULATION RESEARCH vol. 51, (6) 822-822.
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