Publications:  Mr Duco Koenis

Van Der Stoel M, Schimmel L, Nawaz K, Van Stalborch AM, De Haan A, Klaus-Bergmann A, Valent ET, Koenis DS et al.(2020). DLC1 is a direct target of activated YAP/TAZ that drives collective migration and sprouting angiogenesis. Journal of Cell Science vol. 133, (3)

Flak MB, Koenis DS, Sobrino A, Smith J, Pistorius K, Palmas F, Dalli J(2020). GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections. Journal of Clinical Investigation vol. 130, (1) 359-373.

Koenis DS, Medzikovic L, Vos M, Beldman TJ, Van Loenen PB, Van Tiel CM, Hamers AAJ, Rubio IO et al.(2018). Nur77 variants solely comprising the amino-terminal domain activate hypoxia-inducible factor-1 α and affect bone marrow homeostasis in mice and humans. Journal of Biological Chemistry vol. 293, (39) 15070-15083.

Koenis DS, Medzikovic L, van Loenen PB, van Weeghel M, Huveneers S, Vos M, Evers-van Gogh IJ, Van den Bossche J et al.(2018). Nuclear Receptor Nur77 Limits the Macrophage Inflammatory Response through Transcriptional Reprogramming of Mitochondrial Metabolism. Cell Reports vol. 24, (8) 2127-2140.e7.

Kurakula K, Koenis DS, Herzik MA, Liu Y, Craft JW, van Loenen PB, Vos M, Tran MK et al.(2018). Structural and cellular mechanisms of peptidyl-prolyl isomerase Pin1-mediated enhancement of tissue factor gene expression, protein half-life, and pro-coagulant activity. Haematologica vol. 103, (6) 1073-1082.

Medzikovic L, van Roomen C, Baartscheer A, van Loenen PB, de Vos J, Bakker ENTP, Koenis DS, Damanafshan A et al.(2018). Nur77 protects against adverse cardiac remodelling by limiting Neuropeptide Y signalling in the sympathoadrenal-cardiac axis. Cardiovasc Res

Nelson JK, Koenis DS, Scheij S, Cook ECL, Moeton M, Santos A, Lobaccaro JMA, Baron S et al.(2017). EEPD1 Is a Novel LXR Target Gene in Macrophages Which Regulates ABCA1 Abundance and Cholesterol Efflux. Arteriosclerosis, Thrombosis, and Vascular Biology vol. 37, (3) 423-432.

Cook ECL, Nelson JK, Sorrentino V, Koenis D, Moeton M, Scheij S, Ottenhoff R, Bleijlevens B et al.(2017). Identification of the ER-resident E3 ubiquitin ligase RNF145 as a novel LXR-regulated gene. PLOS ONE vol. 12, (2) e0172721-e0172721.

Hamers AAJ, Argmann C, Moerland PD, Koenis DS, Marinkovi¿ G, Sokolovi¿ M, de Vos AF, de Vries CJM et al.(2016). Nur77-deficiency in bone marrow-derived macrophages modulates inflammatory responses, extracellular matrix homeostasis, phagocytosis and tolerance. BMC Genomics vol. 17, (1)

Tran MK, Kurakula K, Koenis DS, de Vries CJM(2016). Protein-protein interactions of the LIM-only protein FHL2 and functional implication of the interactions relevant in cardiovascular disease. Biochimica et Biophysica Acta - Molecular Cell Research vol. 1863, (2) 219-228.

Kurakula K, Sommer D, Sokolovic M, Moerland PD, Scheij S, van Loenen PB, Koenis DS, Zelcer N et al.(2015). LIM-only protein FHL2 is a positive regulator of liver X receptors in smooth muscle cells involved in lipid homeostasis. Molecular and Cellular Biology vol. 35, (1) 52-62.

Kurakula K, Koenis DS, van Tiel CM, de Vries CJM(2014). NR4A nuclear receptors are orphans but not lonesome. Biochimica et Biophysica Acta - Molecular Cell Research vol. 1843, (11) 2543-2555.

van Tiel CM, Kurakula K, Koenis DS, van der Wal E, de Vries CJM(2012). Dual function of Pin1 in NR4A nuclear receptor activation: Enhanced activity of NR4As and increased Nur77 protein stability. Biochimica et Biophysica Acta - Molecular Cell Research vol. 1823, (10) 1894-1904.