Publications:  Prof Victoria Marta Sanz-Moreno

McLeod R, Kumar R, Papadatos-Pastos D, Mateo J, Brown J, Ingles Garces AH, Ruddle R, Decordova SA et al.(2020). First-in-human study of AT13148, a dual ROCK-AKT inhibitor in patients with solid tumors. Clin Cancer Res

Wong PP, Muñoz-Félix JM, Hijazi M, Kim H, Robinson SD, De Luxán-Delgado B, Rodríguez-Hernández I, Maiques O et al.(2020). Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells. Cell vol. 181, (6) 1346-1363.e21.

Samain R, Sanz-Moreno V(2020). Cancer-associated fibroblasts: activin A adds another string to their bow. EMBO Molecular Medicine vol. 12, (4)

Orgaz JL, Crosas-Molist E, Sadok A, Perdrix-Rosell A, Maiques O, Rodriguez-Hernandez I, Monger J, Mele S et al.(2020). Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance. Cancer Cell vol. 37, (1) 85-103.e9.

Valcarcel-Jimenez L, Macchia A, Crosas-Molist E, Schaub-Clerigue A, Camacho L, Martín-Martín N, Cicogna P, Viera-Bardon C et al.(2019). PGC1a suppresses prostate cancer cell invasion through ERRA transcriptional control. Cancer Research vol. 79, (24) 6153-6165.

Foxall E, Staszowska A, Hirvonen LM, Georgouli M, Ciccioli M, Rimmer A, Williams L, Calle Y et al.(2019). PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells. Cell Reports vol. 29, (11) 3385-3393.e6.

Rosel D, Fernandes M, Sanz-Moreno V, Brábek J(2019). Migrastatics: Redirecting R&D in Solid Cancer Towards Metastasis?. Trends Cancer vol. 5, (12) 755-756.

Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J et al.(2019). Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease. Journal of Pathology vol. 249, (4) 523-535.

López-Luque J, Bertran E, Crosas-Molist E, Maiques O, Malfettone A, Caja L, Serrano T, Ramos E et al.(2019). Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition. Cancer Letters vol. 464, 15-24.

Georgouli M, Herraiz C, Crosas-Molist E, Fanshawe B, Maiques O, Perdrix A, Pandya P, Rodriguez-Hernandez I et al.(2019). Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell vol. 176, (4) 757-774.e23.

Sanz-Moreno V, Balkwill FR(2018). Mets and NETs: The Awakening Force. Immunity vol. 49, (5) 798-800.

Muliaditan T, Caron J, Okesola M, Opzoomer JW, Kosti P, Georgouli M, Gordon P, Lall S et al.(2018). Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis. Nature Communications vol. 9, (1) Article 2951,

Maiques O, Barceló C, Panosa A, Pijuan J, Orgaz JL, Rodriguez-Hernandez I, Matas-Nadal C, Tell G et al.(2018). T-type calcium channels drive migration/invasion in BRAFV600E melanoma cells through Snail1. Pigment Cell and Melanoma Research vol. 31, (4) 484-495.

Krupina K, Kleiss C, Awal S, Rodriguez-Hernandez I, Sanz-Moreno V, Sumara I(2018). UBASH3B-mediated silencing of the mitotic checkpoint: Therapeutic perspectives in cancer. Molecular and Cellular Oncology vol. 5, (2)

Crosas-Molist E, Bertran E, Rodriguez-Hernandez I, Herraiz C, Cantelli G, Fabra A, Sanz-Moreno V, Fabregat I(2017). The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination. Oncogene vol. 36, (21) 3002-3014.

Cantelli G, Crosas-Molist E, Georgouli M, Sanz-Moreno V(2017). TGFΒ-induced transcription in cancer. Seminars in Cancer Biology vol. 42, 60-69.

Saul L, Ilieva KM, Bax HJ, Karagiannis P, Correa I, Rodriguez-Hernandez I, Josephs DH, Tosi I et al.(2016). IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin. Scientific Reports vol. 6,

Herraiz C, Crosas-Molist E, Sanz-Moreno V(2016). Reactive oxygen species and tumor dissemination: Allies no longer. Molecular and Cellular Oncology vol. 3, (2)

Herraiz C, Calvo F, Pandya P, Cantelli G, Rodriguez-Hernandez I, Orgaz JL, Kang N, Chu T et al.(2016). Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance between DNA Damage and Tumor Dissemination. Journal of the National Cancer Institute vol. 108, (1)

Rodriguez-Hernandez I, Cantelli G, Bruce F, Sanz-Moreno V(2016). Rho, ROCK and actomyosin contractility in metastasis as drug targets [version 1; referees: 2 approved]. F1000Research vol. 5,

Albrengues J, Bertero T, Grasset E, Bonan S, Maiel M, Bourget I, Philippe C, Herraiz Serrano C et al.(2015). Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts. Nature Communications vol. 6, (1) Article 10204,

Cantelli G, Orgaz JL, Rodriguez-Hernandez I, Karagiannis P, Maiques O, Matias-Guiu X, Nestle FO, Marti RM et al.(2015). TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination. Current Biology vol. 25, (22) 2899-2914.

Orgaz JL, Pandya P, Dalmeida R, Karagiannis P, Sanchez-Laorden B, Viros A, Albrengues J, Nestle FO et al.(2014). Diverse matrix metalloproteinase functions regulate cancer amoeboid migration. Nature Communications vol. 5, (1) Article 4255,