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Publications:  Prof Victoria Marta Sanz-Moreno

McLeod R, Kumar R, Papadatos-Pastos D, Mateo J, Brown J, Ingles Garces AH, Ruddle R, Decordova SA et al.(2020). First-in-human study of AT13148, a dual ROCK-AKT inhibitor in patients with solid tumors. Clin Cancer Res
10.1158/1078-0432.CCR-20-0700
Wong PP, Muñoz-Félix JM, Hijazi M, Kim H, Robinson SD, De Luxán-Delgado B, Rodríguez-Hernández I, Maiques O et al.(2020). Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells. Cell vol. 181, (6) 1346-1363.e21.
10.1016/j.cell.2020.02.003
Samain R, Sanz-Moreno V(2020). Cancer-associated fibroblasts: activin A adds another string to their bow. EMBO Molecular Medicine vol. 12, (4)
10.15252/emmm.202012102
Orgaz JL, Crosas-Molist E, Sadok A, Perdrix-Rosell A, Maiques O, Rodriguez-Hernandez I, Monger J, Mele S et al.(2020). Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance. Cancer Cell vol. 37, (1) 85-103.e9.
10.1016/j.ccell.2019.12.003
Valcarcel-Jimenez L, Macchia A, Crosas-Molist E, Schaub-Clerigue A, Camacho L, Martín-Martín N, Cicogna P, Viera-Bardon C et al.(2019). PGC1a suppresses prostate cancer cell invasion through ERRA transcriptional control. Cancer Research vol. 79, (24) 6153-6165.
10.1158/0008-5472.CAN-19-1231
Foxall E, Staszowska A, Hirvonen LM, Georgouli M, Ciccioli M, Rimmer A, Williams L, Calle Y et al.(2019). PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells. Cell Reports vol. 29, (11) 3385-3393.e6.
10.1016/j.celrep.2019.11.016
Rosel D, Fernandes M, Sanz-Moreno V, Brábek J(2019). Migrastatics: Redirecting R&D in Solid Cancer Towards Metastasis?. Trends Cancer vol. 5, (12) 755-756.
10.1016/j.trecan.2019.10.011
Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J et al.(2019). Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease. Journal of Pathology vol. 249, (4) 523-535.
10.1002/path.5340
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59784
López-Luque J, Bertran E, Crosas-Molist E, Maiques O, Malfettone A, Caja L, Serrano T, Ramos E et al.(2019). Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition. Cancer Letters vol. 464, 15-24.
10.1016/j.canlet.2019.08.011
Georgouli M, Herraiz C, Crosas-Molist E, Fanshawe B, Maiques O, Perdrix A, Pandya P, Rodriguez-Hernandez I et al.(2019). Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell vol. 176, (4) 757-774.e23.
10.1016/j.cell.2018.12.038
https://qmro.qmul.ac.uk/xmlui/handle/123456789/58916
Sanz-Moreno V, Balkwill FR(2018). Mets and NETs: The Awakening Force. Immunity vol. 49, (5) 798-800.
10.1016/j.immuni.2018.11.009
https://qmro.qmul.ac.uk/xmlui/handle/123456789/61448
Muliaditan T, Caron J, Okesola M, Opzoomer JW, Kosti P, Georgouli M, Gordon P, Lall S et al.(2018). Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis. Nature Communications vol. 9, (1) Article 2951,
10.1038/s41467-018-05346-7
Maiques O, Barceló C, Panosa A, Pijuan J, Orgaz JL, Rodriguez-Hernandez I, Matas-Nadal C, Tell G et al.(2018). T-type calcium channels drive migration/invasion in BRAFV600E melanoma cells through Snail1. Pigment Cell and Melanoma Research vol. 31, (4) 484-495.
10.1111/pcmr.12690
Krupina K, Kleiss C, Awal S, Rodriguez-Hernandez I, Sanz-Moreno V, Sumara I(2018). UBASH3B-mediated silencing of the mitotic checkpoint: Therapeutic perspectives in cancer. Molecular and Cellular Oncology vol. 5, (2)
10.1080/23723556.2016.1271494
Crosas-Molist E, Bertran E, Rodriguez-Hernandez I, Herraiz C, Cantelli G, Fabra A, Sanz-Moreno V, Fabregat I(2017). The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination. Oncogene vol. 36, (21) 3002-3014.
10.1038/onc.2016.454
Cantelli G, Crosas-Molist E, Georgouli M, Sanz-Moreno V(2017). TGFΒ-induced transcription in cancer. Seminars in Cancer Biology vol. 42, 60-69.
10.1016/j.semcancer.2016.08.009
Saul L, Ilieva KM, Bax HJ, Karagiannis P, Correa I, Rodriguez-Hernandez I, Josephs DH, Tosi I et al.(2016). IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin. Scientific Reports vol. 6,
10.1038/srep29736
Herraiz C, Crosas-Molist E, Sanz-Moreno V(2016). Reactive oxygen species and tumor dissemination: Allies no longer. Molecular and Cellular Oncology vol. 3, (2)
10.1080/23723556.2015.1127313
Herraiz C, Calvo F, Pandya P, Cantelli G, Rodriguez-Hernandez I, Orgaz JL, Kang N, Chu T et al.(2016). Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance between DNA Damage and Tumor Dissemination. Journal of the National Cancer Institute vol. 108, (1)
10.1093/jnci/djv289
Rodriguez-Hernandez I, Cantelli G, Bruce F, Sanz-Moreno V(2016). Rho, ROCK and actomyosin contractility in metastasis as drug targets [version 1; referees: 2 approved]. F1000Research vol. 5,
10.12688/F1000RESEARCH.7909.1
Albrengues J, Bertero T, Grasset E, Bonan S, Maiel M, Bourget I, Philippe C, Herraiz Serrano C et al.(2015). Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts. Nature Communications vol. 6, (1) Article 10204,
10.1038/ncomms10204
Cantelli G, Orgaz JL, Rodriguez-Hernandez I, Karagiannis P, Maiques O, Matias-Guiu X, Nestle FO, Marti RM et al.(2015). TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination. Current Biology vol. 25, (22) 2899-2914.
10.1016/j.cub.2015.09.054
Orgaz JL, Pandya P, Dalmeida R, Karagiannis P, Sanchez-Laorden B, Viros A, Albrengues J, Nestle FO et al.(2014). Diverse matrix metalloproteinase functions regulate cancer amoeboid migration. Nature Communications vol. 5, (1) Article 4255,
10.1038/ncomms5255
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