Publications:  Prof Victoria Marta Sanz-Moreno

McLeod R, Kumar R, Papadatos-Pastos D, Mateo J, Brown JS, Garces AHI, Ruddle R, Decordova S et al.(2020). First-in-Human Study of AT13148, a Dual ROCK-AKT Inhibitor in Patients with Solid Tumors. Clin Cancer Res vol. 26, (18) 4777-4784.

Wong PP, Muñoz-Félix JM, Hijazi M, Kim H, Robinson SD, De Luxán-Delgado B, Rodríguez-Hernández I, Maiques O et al.(2020). Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells. Cell vol. 181, (6) 1346-1363.e21.

Samain R, Sanz-Moreno V(2020). Cancer-associated fibroblasts: activin A adds another string to their bow. EMBO Molecular Medicine vol. 12, (4)

Orgaz JL, Crosas-Molist E, Sadok A, Perdrix-Rosell A, Maiques O, Rodriguez-Hernandez I, Monger J, Mele S et al.(2020). Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance. Cancer Cell vol. 37, (1) 85-103.e9.

Valcarcel-Jimenez L, Macchia A, Crosas-Molist E, Schaub-Clerigue A, Camacho L, Martín-Martín N, Cicogna P, Viera-Bardon C et al.(2019). PGC1a suppresses prostate cancer cell invasion through ERRA transcriptional control. Cancer Research vol. 79, (24) 6153-6165.

Foxall E, Staszowska A, Hirvonen LM, Georgouli M, Ciccioli M, Rimmer A, Williams L, Calle Y et al.(2019). PAK4 Kinase Activity Plays a Crucial Role in the Podosome Ring of Myeloid Cells. Cell Reports vol. 29, (11) 3385-3393.e6.

Rosel D, Fernandes M, Sanz-Moreno V, Brábek J(2019). Migrastatics: Redirecting R&D in Solid Cancer Towards Metastasis?. Trends Cancer vol. 5, (12) 755-756.

Dukinfield M, Maniati E, Reynolds LE, Aubdool A, Baliga RS, D'Amico G, Maiques O, Wang J et al.(2019). Repurposing an anti-cancer agent for the treatment of hypertrophic heart disease. Journal of Pathology vol. 249, (4) 523-535.

López-Luque J, Bertran E, Crosas-Molist E, Maiques O, Malfettone A, Caja L, Serrano T, Ramos E et al.(2019). Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition. Cancer Letters vol. 464, 15-24.

Georgouli M, Herraiz C, Crosas-Molist E, Fanshawe B, Maiques O, Perdrix A, Pandya P, Rodriguez-Hernandez I et al.(2019). Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell vol. 176, (4) 757-774.e23.

Sanz-Moreno V, Balkwill FR(2018). Mets and NETs: The Awakening Force. Immunity vol. 49, (5) 798-800.

Muliaditan T, Caron J, Okesola M, Opzoomer JW, Kosti P, Georgouli M, Gordon P, Lall S et al.(2018). Macrophages are exploited from an innate wound healing response to facilitate cancer metastasis. Nat Commun vol. 9, (1)

Maiques O, Barceló C, Panosa A, Pijuan J, Orgaz JL, Rodriguez-Hernandez I, Matas-Nadal C, Tell G et al.(2018). T-type calcium channels drive migration/invasion in BRAFV600E melanoma cells through Snail1. Pigment Cell and Melanoma Research vol. 31, (4) 484-495.

Krupina K, Kleiss C, Awal S, Rodriguez-Hernandez I, Sanz-Moreno V, Sumara I(2018). UBASH3B-mediated silencing of the mitotic checkpoint: Therapeutic perspectives in cancer. Molecular and Cellular Oncology vol. 5, (2)

Crosas-Molist E, Bertran E, Rodriguez-Hernandez I, Herraiz C, Cantelli G, Fabra A, Sanz-Moreno V, Fabregat I(2017). The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination. Oncogene vol. 36, (21) 3002-3014.

Cantelli G, Crosas-Molist E, Georgouli M, Sanz-Moreno V(2017). TGFΒ-induced transcription in cancer. Seminars in Cancer Biology vol. 42, 60-69.

Saul L, Ilieva KM, Bax HJ, Karagiannis P, Correa I, Rodriguez-Hernandez I, Josephs DH, Tosi I et al. (2016). Abstract A116: IgG antibody switching and clonal expansion in melanoma and normal skin microenvironments. Conference: Cancer Immunology Research AACRa116-a116.

Saul L, Ilieva KM, Bax HJ, Karagiannis P, Correa I, Rodriguez-Hernandez I, Josephs DH, Tosi I et al.(2016). IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin. Scientific Reports vol. 6,

Herraiz C, Crosas-Molist E, Sanz-Moreno V(2016). Reactive oxygen species and tumor dissemination: Allies no longer. Molecular and Cellular Oncology vol. 3, (2)

Herraiz C, Calvo F, Pandya P, Cantelli G, Rodriguez-Hernandez I, Orgaz JL, Kang N, Chu T et al.(2016). Reactivation of p53 by a Cytoskeletal Sensor to Control the Balance between DNA Damage and Tumor Dissemination. Journal of the National Cancer Institute vol. 108, (1)

Rodriguez-Hernandez I, Cantelli G, Bruce F, Sanz-Moreno V(2016). Rho, ROCK and actomyosin contractility in metastasis as drug targets [version 1; referees: 2 approved]. F1000Research vol. 5,

Albrengues J, Bertero T, Grasset E, Bonan S, Maiel M, Bourget I, Philippe C, Herraiz Serrano C et al.(2015). Epigenetic switch drives the conversion of fibroblasts into proinvasive cancer-associated fibroblasts. Nat Commun vol. 6,

Cantelli G, Orgaz JL, Rodriguez-Hernandez I, Karagiannis P, Maiques O, Matias-Guiu X, Nestle FO, Marti RM et al.(2015). TGF-β-Induced Transcription Sustains Amoeboid Melanoma Migration and Dissemination. Current Biology vol. 25, (22) 2899-2914.

Orgaz JL, Pandya P, Dalmeida R, Karagiannis P, Sanchez-Laorden B, Viros A, Albrengues J, Nestle FO et al.(2014). Diverse matrix metalloproteinase functions regulate cancer amoeboid migration. Nat Commun vol. 5,