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Research

Publications: Dr Eva Crosas Molist

Crosas-Molist E, Samain R, Kohlhammer L, Orgaz JL, George SL, Maiques O, Barcelo J, Sanz-Moreno V ( 2022 ) . RHO GTPase SIGNALING IN CANCER PROGRESSION AND DISSEMINATION . Physiological Reviews vol. 102 , ( 1 ) 455 - 510 .
Peñuelas-Haro I, Espinosa-Sotelo R, Crosas-Molist E, Herranz-Itúrbide M, Caballero-Díaz D, Alay A, Solé X, Ramos E et al. ( 2022 ) . The NADPH oxidase NOX4 regulates redox and metabolic homeostasis preventing HCC progression . Hepatology
de Winde CM, George SL, Crosas-Molist E, Hari-Gupta Y, Arp AB, Benjamin AC, Millward LJ, Makris S et al. ( 2021 ) . Podoplanin drives dedifferentiation and amoeboid invasion of melanoma . iScience vol. 24 , ( 9 )
Maiques O, Fanshawe B, Crosas-Molist E, Rodriguez-Hernandez I, Volpe A, Cantelli G, Boehme L, Orgaz JL et al. ( 2021 ) . A preclinical pipeline to evaluate migrastatics as therapeutic agents in metastatic melanoma . British Journal of Cancer vol. 125 , ( 5 ) 699 - 713 .
Herranz-Itúrbide M, López-Luque J, Gonzalez-Sanchez E, Caballero-Díaz D, Crosas-Molist E, Martín-Mur B, Gut M, Esteve-Codina A et al. ( 2021 ) . NADPH oxidase 4 (Nox4) deletion accelerates liver regeneration in mice . Redox Biology vol. 40 ,
Herranz-Itúrbide M, López-Luque J, Gonzalez-Sanchez E, Caballero-Díaz D, Crosas-Molist E, Martín-Mur B, Gut M, Esteve-Codina A et al. ( 2021 ) . NADPH oxidase 4 (Nox4) deletion accelerates liver regeneration in mice . Free Radical Biology and Medicine . vol. 165 ,
Peñuelas-Haro I, Bertran E, Crosas-Molist E, Santacatterina F, Sebastian D, Marin S, Martínez-Chantar M-L, Cascante M et al. ( 2021 ) . The NADPH oxidase NOX4 regulates metabolism in hepatocellular carcinoma cells . Free Radical Biology and Medicine . vol. 165 ,
Penuelas-Haro I, Bertran E, Crosas-Molist E, Santacatterina F, Marin S, Isabel Hernandez-Alvarez M, Luz Martinez-Chantar M, Cascante M et al. ( 2020 ) . The NADPH oxidase NOX4 regulates lipid metabolism, which contributes to its tumour suppressor actions in hepatocellular carcinoma . JOURNAL OF HEPATOLOGY . vol. 73 , S89 - S89 .
Orgaz JL, Crosas-Molist E, Sadok A, Perdrix-Rosell A, Maiques O, Rodriguez-Hernandez I, Monger J, Mele S et al. ( 2020 ) . Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance . Cancer Cell vol. 37 , ( 1 ) 85 - 103.e9 .
Valcarcel-Jimenez L, Macchia A, Crosas-Molist E, Schaub-Clerigue A, Camacho L, Martín-Martín N, Cicogna P, Viera-Bardon C et al. ( 2019 ) . PGC1a suppresses prostate cancer cell invasion through ERRA transcriptional control . Cancer Research vol. 79 , ( 24 ) 6153 - 6165 .
López-Luque J, Bertran E, Crosas-Molist E, Maiques O, Malfettone A, Caja L, Serrano T, Ramos E et al. ( 2019 ) . Downregulation of Epidermal Growth Factor Receptor in hepatocellular carcinoma facilitates Transforming Growth Factor-β-induced epithelial to amoeboid transition . Cancer Letters vol. 464 , 15 - 24 .
Georgouli M, Herraiz C, Crosas-Molist E, Fanshawe B, Maiques O, Perdrix A, Pandya P, Rodriguez-Hernandez I et al. ( 2019 ) . Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment . Cell vol. 176 , ( 4 ) 757 - 774.e23 .
Jiménez-Altayó F, Meirelles T, Crosas-Molist E, Sorolla MA, del Blanco DG, López-Luque J, Mas-Stachurska A, Siegert AM et al. ( 2018 ) . Redox stress in Marfan syndrome: Dissecting the role of the NADPH oxidase NOX4 in aortic aneurysm . Free Radical Biology and Medicine vol. 118 , 44 - 58 .
Crosas-Molist E, Bertran E, Rodriguez-Hernandez I, Herraiz C, Cantelli G, Fabra A, Sanz-Moreno V, Fabregat I ( 2017 ) . The NADPH oxidase NOX4 represses epithelial to amoeboid transition and efficient tumour dissemination . Oncogene vol. 36 , ( 21 ) 3002 - 3014 .
Malfettone A, Soukupova J, Bertran E, Crosas-Molist E, Lastra R, Fernando J, Koudelkova P, Rani B et al. ( 2017 ) . Transforming growth factor-β-induced plasticity causes a migratory stemness phenotype in hepatocellular carcinoma . Cancer Letters vol. 392 , 39 - 50 .
Cantelli G, Crosas-Molist E, Georgouli M, Sanz-Moreno V ( 2017 ) . TGFΒ-induced transcription in cancer . Seminars in Cancer Biology vol. 42 , 60 - 69 .
Herraiz C, Crosas-Molist E, Sanz-Moreno V ( 2016 ) . Reactive oxygen species and tumor dissemination: Allies no longer . Molecular and Cellular Oncology vol. 3 , ( 2 )
López-Luque J, Caballero-Díaz D, Martinez-Palacián A, Roncero C, Moreno-Càceres J, García-Bravo M, Grueso E, Fernández A et al. ( 2016 ) . Dissecting the role of epidermal growth factor receptor catalytic activity during liver regeneration and hepatocarcinogenesis . Hepatology vol. 63 , ( 2 ) 604 - 619 .
Crosas-Molist E, Fabregat I ( 2015 ) . Role of NADPH oxidases in the redox biology of liver fibrosis . Redox Biology vol. 6 , 106 - 111 .
Crosas-Molist E, Meirelles T, López-Luque J, Serra-Peinado C, Selva J, Caja L, Gorbenko Del Blanco D, Uriarte JJ et al. ( 2015 ) . Vascular smooth muscle cell phenotypic changes in patients with marfan syndrome . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 35 , ( 4 ) 960 - 972 .
Crosas-Molist E, Bertran E, Fabregat I ( 2015 ) . Cross-talk between TGF-β and NADPH oxidases during liver fibrosis and hepatocarcinogenesis . Current Pharmaceutical Design vol. 21 , ( 41 ) 5964 - 5976 .
Crosas-Molist E, Bertran E, Sancho P, López-Luque J, Fernando J, Sánchez A, Fernández M, Navarro E et al. ( 2014 ) . The NADPH oxidase NOX4 inhibits hepatocyte proliferation and liver cancer progression . Free Radical Biology and Medicine vol. 69 , 338 - 347 .
Bertran E, Crosas-Molist E, Sancho P, Caja L, Lopez-Luque J, Navarro E, Egea G, Lastra R et al. ( 2013 ) . Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells . Hepatology vol. 58 , ( 6 ) 2032 - 2044 .
Sancho P, Mainez J, Crosas-Molist E, Roncero C, Fernández-Rodriguez CM, Pinedo F, Huber H, Eferl R et al. ( 2012 ) . NADPH Oxidase NOX4 Mediates Stellate Cell Activation and Hepatocyte Cell Death during Liver Fibrosis Development . PLoS ONE vol. 7 , ( 9 )
Crosas-Molist E, Sánchez A, Fernández M, Sancho P, Bertran E, Fabregat I ( 2012 ) . 409 IMPLICATION OF NADPH OXIDASES (NOXES) IN LIVER REGENERATION . Journal of Hepatology . vol. 56 , s163 - s164 .