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Publications:  Dr Andrew Durham

Durham AL, Al Jaaly E, Graham R, Brook PO, Bae JH, Heesom KJ, Postle AD, Lavender P et al.(2020). Multi-omic analysis of the effects of low frequency ventilation during cardiopulmonary bypass surgery. International Journal of Cardiology vol. 309, 40-47.
10.1016/j.ijcard.2020.03.054
https://qmro.qmul.ac.uk/xmlui/handle/123456789/65156
McKiernan PJ, Smith SGJ, Durham AL, Adcock IM, McElvaney NG, Greene CM(2019). The Estrogen-Induced miR-19 Downregulates Secretory Leucoprotease Inhibitor Expression in Monocytes. Journal of Innate Immunity vol. 12, (1) 90-102.
10.1159/000500419
Durham AL, Speer MY, Scatena M, Giachelli CM, Shanahan CM(2018). Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness. Cardiovascular Research vol. 114, (4) 590-600.
10.1093/cvr/cvy010
Rossios C, Pavlidis S, Hoda U, Kuo C-H, Wiegman C, Russell K, Sun K, Loza MJ et al.(2018). Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma. J Allergy Clin Immunol vol. 141, (2) 560-570.
10.1016/j.jaci.2017.02.045
Rossios C, Pavlidis S, Gibeon D, Mumby S, Durham A, Ojo O, Horowitz D, Loza M et al.(2017). Impaired innate immune gene profiling in airway smooth muscle cells from chronic cough patients. Bioscience Reports vol. 37, (6)
10.1042/bsr20171090
Shim JM, Lee JS, Russell KE, Wiegman CH, Barnes PJ, Fear D, Adcock IM, Durham AL(2017). BET proteins are a key component of immunoglobulin gene expression. Epigenomics vol. 9, (4) 393-406.
10.2217/epi-2016-0147
Caramori G, Casolari P, Barczyk A, Durham AL, Di Stefano A, Adcock I(2016). COPD immunopathology. Seminars in Immunopathology vol. 38, (4) 497-515.
10.1007/s00281-016-0561-5
Lee J, Machin M, Russell KE, Pavlidis S, Zhu J, Barnes PJ, Chung KF, Adcock IM et al.(2016). Corticosteroid modulation of immunoglobulin expression and B‐cell function in COPD. The FASEB Journal vol. 30, (5) 2014-2026.
10.1096/fj.201500135
Footitt J, Mallia P, Durham AL, Ho WE, Trujillo-Torralbo M-B, Telcian AG, Del Rosario A, Chang C et al.(2016). Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD. Chest vol. 149, (1) 62-73.
10.1378/chest.14-2637
Durham AL, Caramori G, Chung KF, Adcock IM(2016). Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease. Translational Research vol. 167, (1) 192-203.
10.1016/j.trsl.2015.08.004
Ngkelo A, Hoffmann RF, Durham AL, Marwick JA, Brandenburg SM, de Bruin HG, Jonker MR, Rossios C et al.(2015). Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD. American Journal of Physiology-Lung Cellular and Molecular Physiology vol. 309, (10) L1112-L1123.
10.1152/ajplung.00077.2015
Durham AL, Adcock IM(2015). The relationship between COPD and lung cancer. Lung Cancer vol. 90, (2) 121-127.
10.1016/j.lungcan.2015.08.017
Brook PO, Perry MM, Adcock IM, Durham AL(2015). Epigenome-modifying tools in asthma. Epigenomics vol. 7, (6) 1017-1032.
10.2217/epi.15.53
Perry MM, Durham AL, Austin PJ, Adcock IM, Chung KF(2015). BET bromodomains regulate TGF-β-induced proliferation and cytokine release in asthmatic airway smooth muscle. Journal of Biological Chemistry vol. 290, (14) 9111-9121.
10.1074/jbc.M114.612671
Di Stefano A, Caramori G, Barczyk A, Vicari C, Brun P, Zanini A, Cappello F, Garofano E et al.(2014). Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD. Thorax vol. 69, (6) 516-524.
10.1136/thoraxjnl-2012-203062
Durham AL, Adcock IM(2013). Basic science: Epigenetic programming and the respiratory system. Breathe vol. 9, (4) 278-288.
10.1183/20734735.000413
Durham AL, McLaren A, Hayes BP, Caramori G, Clayton CL, Barnes PJ, Chung KF, Adcock IM(2013). Regulation of Wnt4 in chronic obstructive pulmonary disease. The FASEB Journal vol. 27, (6) 2367-2381.
10.1096/fj.12-217083
Yao X, Zha W, Song W, He H, Huang M, Jazrawi E, Lavender P, Barnes PJ et al.(2012). Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping. Biochemical and Biophysical Research Communications vol. 417, (3) 996-1001.
10.1016/j.bbrc.2011.12.069
Durham AL, Wiegman C, Adcock IM(2011). Epigenetics of asthma. Biochimica et Biophysica Acta (BBA) - General Subjects vol. 1810, (11) 1103-1109.
10.1016/j.bbagen.2011.03.006
Durham A, Adcock IM, Tliba O(2011). Steroid Resistance in Severe Asthma: Current Mechanisms and Future Treatment. Current Pharmaceutical Design vol. 17, (7) 674-684.
10.2174/138161211795428984
Durham A, Chou P-C, Kirkham P, Adcock IM(2010). Epigenetics in asthma and other inflammatory lung diseases. Epigenomics vol. 2, (4) 523-537.
10.2217/epi.10.27
Ford PA, Durham AL, Russell REK, Gordon F, Adcock IM, Barnes PJ(2010). Treatment Effects of Low-Dose Theophylline Combined With an Inhaled Corticosteroid in COPD. Chest vol. 137, (6) 1338-1344.
10.1378/chest.09-2363
Bosse¿ JT, Durham AL, Rycroft AN, Kroll JS, Langford PR(2009). New Plasmid Tools for Genetic Analysis of Actinobacillus pleuropneumoniae and Other Pasteurellaceae. Applied and Environmental Microbiology vol. 75, (19) 6124-6131.
10.1128/aem.00809-09
Adcock IM, Chou P-C, Durham A, Ford P(2009). Overcoming steroid unresponsiveness in airways disease. Biochemical Society Transactions vol. 37, (4) 824-829.
10.1042/bst0370824
Williams AS, Issa R, Durham A, Leung S-Y, Kapoun A, Medicherla S, Higgins LS, Adcock IM et al.(2008). Role of p38 mitogen-activated protein kinase in ozone-induced airway hyperresponsiveness and inflammation. European Journal of Pharmacology vol. 600, (1-3) 117-122.
10.1016/j.ejphar.2008.09.031
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