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Publications:  Dr Andrew Durham

Durham AL, Al Jaaly E, Graham R, Brook PO, Bae JH, Heesom KJ, Postle AD, Lavender P et al.(2020). Multi-omic analysis of the effects of low frequency ventilation during cardiopulmonary bypass surgery. International Journal of Cardiology vol. 309, 40-47.
McKiernan PJ, Smith SGJ, Durham AL, Adcock IM, McElvaney NG, Greene CM(2019). The Estrogen-Induced miR-19 Downregulates Secretory Leucoprotease Inhibitor Expression in Monocytes. Journal of Innate Immunity vol. 12, (1) 90-102.
Durham AL, Speer MY, Scatena M, Giachelli CM, Shanahan CM(2018). Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness. Cardiovascular Research vol. 114, (4) 590-600.
Rossios C, Pavlidis S, Hoda U, Kuo C-H, Wiegman C, Russell K, Sun K, Loza MJ et al.(2018). Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma. J Allergy Clin Immunol vol. 141, (2) 560-570.
Rossios C, Pavlidis S, Gibeon D, Mumby S, Durham A, Ojo O, Horowitz D, Loza M et al.(2017). Impaired innate immune gene profiling in airway smooth muscle cells from chronic cough patients. Bioscience Reports vol. 37, (6)
Shim JM, Lee JS, Russell KE, Wiegman CH, Barnes PJ, Fear D, Adcock IM, Durham AL(2017). BET proteins are a key component of immunoglobulin gene expression. Epigenomics vol. 9, (4) 393-406.
Caramori G, Casolari P, Barczyk A, Durham AL, Di Stefano A, Adcock I(2016). COPD immunopathology. Seminars in Immunopathology vol. 38, (4) 497-515.
Lee J, Machin M, Russell KE, Pavlidis S, Zhu J, Barnes PJ, Chung KF, Adcock IM et al.(2016). Corticosteroid modulation of immunoglobulin expression and B‐cell function in COPD. The FASEB Journal vol. 30, (5) 2014-2026.
Footitt J, Mallia P, Durham AL, Ho WE, Trujillo-Torralbo M-B, Telcian AG, Del Rosario A, Chang C et al.(2016). Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD. Chest vol. 149, (1) 62-73.
Durham AL, Caramori G, Chung KF, Adcock IM(2016). Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease. Translational Research vol. 167, (1) 192-203.
Ngkelo A, Hoffmann RF, Durham AL, Marwick JA, Brandenburg SM, de Bruin HG, Jonker MR, Rossios C et al.(2015). Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD. American Journal of Physiology-Lung Cellular and Molecular Physiology vol. 309, (10) L1112-L1123.
Durham AL, Adcock IM(2015). The relationship between COPD and lung cancer. Lung Cancer vol. 90, (2) 121-127.
Brook PO, Perry MM, Adcock IM, Durham AL(2015). Epigenome-modifying tools in asthma. Epigenomics vol. 7, (6) 1017-1032.
Perry MM, Durham AL, Austin PJ, Adcock IM, Chung KF(2015). BET bromodomains regulate TGF-β-induced proliferation and cytokine release in asthmatic airway smooth muscle. Journal of Biological Chemistry vol. 290, (14) 9111-9121.
Di Stefano A, Caramori G, Barczyk A, Vicari C, Brun P, Zanini A, Cappello F, Garofano E et al.(2014). Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD. Thorax vol. 69, (6) 516-524.
Durham AL, Adcock IM(2013). Basic science: Epigenetic programming and the respiratory system. Breathe vol. 9, (4) 278-288.
Durham AL, McLaren A, Hayes BP, Caramori G, Clayton CL, Barnes PJ, Chung KF, Adcock IM(2013). Regulation of Wnt4 in chronic obstructive pulmonary disease. The FASEB Journal vol. 27, (6) 2367-2381.
Yao X, Zha W, Song W, He H, Huang M, Jazrawi E, Lavender P, Barnes PJ et al.(2012). Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping. Biochemical and Biophysical Research Communications vol. 417, (3) 996-1001.
Durham AL, Wiegman C, Adcock IM(2011). Epigenetics of asthma. Biochimica et Biophysica Acta (BBA) - General Subjects vol. 1810, (11) 1103-1109.
Durham A, Adcock IM, Tliba O(2011). Steroid Resistance in Severe Asthma: Current Mechanisms and Future Treatment. Current Pharmaceutical Design vol. 17, (7) 674-684.
Durham A, Chou P-C, Kirkham P, Adcock IM(2010). Epigenetics in asthma and other inflammatory lung diseases. Epigenomics vol. 2, (4) 523-537.
Ford PA, Durham AL, Russell REK, Gordon F, Adcock IM, Barnes PJ(2010). Treatment Effects of Low-Dose Theophylline Combined With an Inhaled Corticosteroid in COPD. Chest vol. 137, (6) 1338-1344.
Bosse¿ JT, Durham AL, Rycroft AN, Kroll JS, Langford PR(2009). New Plasmid Tools for Genetic Analysis of Actinobacillus pleuropneumoniae and Other Pasteurellaceae. Applied and Environmental Microbiology vol. 75, (19) 6124-6131.
Adcock IM, Chou P-C, Durham A, Ford P(2009). Overcoming steroid unresponsiveness in airways disease. Biochemical Society Transactions vol. 37, (4) 824-829.
Williams AS, Issa R, Durham A, Leung S-Y, Kapoun A, Medicherla S, Higgins LS, Adcock IM et al.(2008). Role of p38 mitogen-activated protein kinase in ozone-induced airway hyperresponsiveness and inflammation. European Journal of Pharmacology vol. 600, (1-3) 117-122.
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