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Research
  1. Queen Mary University of London
  2. Research
  3. Publications

Publications: Dr Andrew Durham

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Durham AL, Jaaly EA, Graham R, Brook PO, Bae JH, Heesom KJ, Postle AD, Lavender P et al. ( 2020 ) . Multi-omic analysis of the effects of low frequency ventilation during cardiopulmonary bypass surgery . International Journal of Cardiology vol. 309 , 40 - 47 .
McKiernan PJ, Smith SGJ, Durham AL, Adcock IM, McElvaney NG, Greene CM ( 2019 ) . The Estrogen-Induced miR-19 Downregulates Secretory Leucoprotease Inhibitor Expression in Monocytes . Journal of Innate Immunity vol. 12 , ( 1 ) 90 - 102 .
Durham AL, Speer MY, Scatena M, Giachelli CM, Shanahan CM ( 2018 ) . Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness . Cardiovascular Research vol. 114 , ( 4 ) 590 - 600 .
Rossios C, Pavlidis S, Gibeon D, Mumby S, Durham A, Ojo O, Horowitz D, Loza M et al. ( 2017 ) . Impaired innate immune gene profiling in airway smooth muscle cells from chronic cough patients . Bioscience Reports vol. 37 , ( 6 )
Rossios C, Pavlidis S, Hoda U, Kuo C-H, Wiegman C, Russell K, Sun K, Loza MJ et al. ( 2017 ) . Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma . Journal of Allergy and Clinical Immunology vol. 141 , ( 2 ) 560 - 570 .
Shim JM, Lee JS, Russell KE, Wiegman CH, Barnes PJ, Fear D, Adcock IM, Durham AL ( 2017 ) . BET proteins are a key component of immunoglobulin gene expression . Epigenomics vol. 9 , ( 4 ) 393 - 406 .
Caramori G, Casolari P, Barczyk A, Durham AL, Di Stefano A, Adcock I ( 2016 ) . COPD immunopathology . Seminars in Immunopathology vol. 38 , ( 4 ) 497 - 515 .
Lee J, Machin M, Russell KE, Pavlidis S, Zhu J, Barnes PJ, Chung KF, Adcock IM et al. ( 2016 ) . Corticosteroid modulation of immunoglobulin expression and B‐cell function in COPD . The FASEB Journal vol. 30 , ( 5 ) 2014 - 2026 .
Footitt J, Mallia P, Durham AL, Ho WE, Trujillo-Torralbo M-B, Telcian AG, Del Rosario A, Chang C et al. ( 2016 ) . Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD . CHEST Journal vol. 149 , ( 1 ) 62 - 73 .
Brook PO, Perry MM, Adcock IM, Durham AL ( 2015 ) . Epigenome-modifying tools in asthma . Epigenomics vol. 7 , ( 6 ) 1017 - 1032 .
Durham AL, Adcock IM ( 2015 ) . The relationship between COPD and lung cancer . Lung Cancer vol. 90 , ( 2 ) 121 - 127 .
Ngkelo A, Hoffmann RF, Durham AL, Marwick JA, Brandenburg SM, de Bruin HG, Jonker MR, Rossios C et al. ( 2015 ) . Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD . American Journal of Physiology - Lung Cellular and Molecular Physiology vol. 309 , ( 10 ) l1112 - l1123 .
Durham AL, Caramori G, Chung KF, Adcock IM ( 2015 ) . Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease . Translational Research vol. 167 , ( 1 ) 192 - 203 .
Perry MM, Durham AL, Austin PJ, Adcock IM, Chung KF ( 2015 ) . BET bromodomains regulate TGF-β-induced proliferation and cytokine release in asthmatic airway smooth muscle . Journal of Biological Chemistry vol. 290 , ( 14 ) 9111 - 9121 .
Di Stefano A, Caramori G, Barczyk A, Vicari C, Brun P, Zanini A, Cappello F, Garofano E et al. ( 2014 ) . Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD . Thorax vol. 69 , ( 6 )
Durham AL, Adcock IM ( 2013 ) . Basic science: Epigenetic programming and the respiratory system . Breathe vol. 9 , ( 4 ) 278 - 288 .
Durham AL, McLaren A, Hayes BP, Caramori G, Clayton CL, Barnes PJ, Chung KF, Adcock IM ( 2013 ) . Regulation of Wnt4 in chronic obstructive pulmonary disease . The FASEB Journal vol. 27 , ( 6 ) 2367 - 2381 .
Yao X, Zha W, Song W, He H, Huang M, Jazrawi E, Lavender P, Barnes PJ et al. ( 2011 ) . Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping . Biochemical and Biophysical Research Communications vol. 417 , ( 3 ) 996 - 1001 .
Durham AL, Wiegman C, Adcock IM ( 2011 ) . Epigenetics of asthma . Biochimica et Biophysica Acta vol. 1810 , ( 11 ) 1103 - 1109 .
Durham A, Adcock IM, Tliba O ( 2011 ) . Steroid resistance in severe asthma: current mechanisms and future treatment . Current Pharmaceutical Design vol. 17 , ( 7 ) 674 - 684 .
Durham A, Chou P-C, Kirkham P, Adcock IM ( 2010 ) . Epigenetics in asthma and other inflammatory lung diseases . Epigenomics vol. 2 , ( 4 ) 523 - 537 .
Ford PA, Durham AL, Russell REK, Gordon F, Adcock IM, Barnes PJ ( 2010 ) . Treatment Effects of Low-Dose Theophylline Combined With an Inhaled Corticosteroid in COPD . CHEST Journal vol. 137 , ( 6 ) 1338 - 1344 .
Bossé JT, Durham AL, Rycroft AN, Kroll JS, Langford PR ( 2009 ) . New Plasmid Tools for Genetic Analysis of Actinobacillus pleuropneumoniae and Other Pasteurellaceae▿ . Applied and Environmental Microbiology vol. 75 , ( 19 ) 6124 - 6131 .
Adcock IM, Chou P-C, Durham A, Ford P ( 2009 ) . Overcoming steroid unresponsiveness in airways disease . Biochemical Society Transactions vol. 37 , ( 4 ) 824 - 829 .
Williams AS, Issa R, Durham A, Leung S-Y, Kapoun A, Medicherla S, Higgins LS, Adcock IM et al. ( 2008 ) . Role of p38 mitogen-activated protein kinase in ozone-induced airway hyperresponsiveness and inflammation . European Journal of Pharmacology vol. 600 , ( 1-3 ) 117 - 122 .
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