Publications: Dr Andrew Durham
Durham AL, Al Jaaly E, Graham R, Brook PO, Bae JH, Heesom KJ, Postle AD, Lavender P et al.
(
2020
)
.
Multi-omic analysis of the effects of low frequency ventilation during cardiopulmonary bypass surgery
.
International Journal of Cardiology
vol.
309
,
40
-
47
.
McKiernan PJ, Smith SGJ, Durham AL, Adcock IM, McElvaney NG, Greene CM
(
2019
)
.
The Estrogen-Induced miR-19 Downregulates Secretory Leucoprotease Inhibitor Expression in Monocytes
.
Journal of Innate Immunity
vol.
12
,
(
1
)
90
-
102
.
Durham AL, Speer MY, Scatena M, Giachelli CM, Shanahan CM
(
2018
)
.
Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness
.
Cardiovascular Research
vol.
114
,
(
4
)
590
-
600
.
Rossios C, Pavlidis S, Gibeon D, Mumby S, Durham A, Ojo O, Horowitz D, Loza M et al.
(
2017
)
.
Impaired innate immune gene profiling in airway smooth muscle cells from chronic cough patients
.
Bioscience Reports
vol.
37
,
(
6
)
Rossios C, Pavlidis S, Hoda U, Kuo C-H, Wiegman C, Russell K, Sun K, Loza MJ et al.
(
2017
)
.
Sputum transcriptomics reveal upregulation of IL-1 receptor family members in patients with severe asthma
.
Journal of Allergy and Clinical Immunology
vol.
141
,
(
2
)
560
-
570
.
Shim JM, Lee JS, Russell KE, Wiegman CH, Barnes PJ, Fear D, Adcock IM, Durham AL
(
2017
)
.
BET proteins are a key component of immunoglobulin gene expression
.
Epigenomics
vol.
9
,
(
4
)
393
-
406
.
Caramori G, Casolari P, Barczyk A, Durham AL, Di Stefano A, Adcock I
(
2016
)
.
COPD immunopathology
.
Seminars in Immunopathology
vol.
38
,
(
4
)
497
-
515
.
Lee J, Machin M, Russell KE, Pavlidis S, Zhu J, Barnes PJ, Chung KF, Adcock IM et al.
(
2016
)
.
Corticosteroid modulation of immunoglobulin expression and B‐cell function in COPD
.
The FASEB Journal
vol.
30
,
(
5
)
2014
-
2026
.
Footitt J, Mallia P, Durham AL, Ho WE, Trujillo-Torralbo M-B, Telcian AG, Del Rosario A, Chang C et al.
(
2016
)
.
Oxidative and Nitrosative Stress and Histone Deacetylase-2 Activity in Exacerbations of COPD
.
CHEST Journal
vol.
149
,
(
1
)
62
-
73
.
Brook PO, Perry MM, Adcock IM, Durham AL
(
2015
)
.
Epigenome-modifying tools in asthma
.
Epigenomics
vol.
7
,
(
6
)
1017
-
1032
.
Durham AL, Adcock IM
(
2015
)
.
The relationship between COPD and lung cancer
.
Lung Cancer
vol.
90
,
(
2
)
121
-
127
.
Ngkelo A, Hoffmann RF, Durham AL, Marwick JA, Brandenburg SM, de Bruin HG, Jonker MR, Rossios C et al.
(
2015
)
.
Glycogen synthase kinase-3β modulation of glucocorticoid responsiveness in COPD
.
American Journal of Physiology - Lung Cellular and Molecular Physiology
vol.
309
,
(
10
)
l1112
-
l1123
.
Durham AL, Caramori G, Chung KF, Adcock IM
(
2015
)
.
Targeted anti-inflammatory therapeutics in asthma and chronic obstructive lung disease
.
Translational Research
vol.
167
,
(
1
)
192
-
203
.
Perry MM, Durham AL, Austin PJ, Adcock IM, Chung KF
(
2015
)
.
BET bromodomains regulate TGF-β-induced proliferation and cytokine release in asthmatic airway smooth muscle
.
Journal of Biological Chemistry
vol.
290
,
(
14
)
9111
-
9121
.
Di Stefano A, Caramori G, Barczyk A, Vicari C, Brun P, Zanini A, Cappello F, Garofano E et al.
(
2014
)
.
Innate immunity but not NLRP3 inflammasome activation correlates with severity of stable COPD
.
Thorax
vol.
69
,
(
6
)
Durham AL, Adcock IM
(
2013
)
.
Basic science: Epigenetic programming and the respiratory system
.
Breathe
vol.
9
,
(
4
)
278
-
288
.
Durham AL, McLaren A, Hayes BP, Caramori G, Clayton CL, Barnes PJ, Chung KF, Adcock IM
(
2013
)
.
Regulation of Wnt4 in chronic obstructive pulmonary disease
.
The FASEB Journal
vol.
27
,
(
6
)
2367
-
2381
.
Yao X, Zha W, Song W, He H, Huang M, Jazrawi E, Lavender P, Barnes PJ et al.
(
2011
)
.
Coordinated regulation of IL-4 and IL-13 expression in human T cells: 3C analysis for DNA looping
.
Biochemical and Biophysical Research Communications
vol.
417
,
(
3
)
996
-
1001
.
Durham AL, Wiegman C, Adcock IM
(
2011
)
.
Epigenetics of asthma
.
Biochimica et Biophysica Acta
vol.
1810
,
(
11
)
1103
-
1109
.
Durham A, Adcock IM, Tliba O
(
2011
)
.
Steroid resistance in severe asthma: current mechanisms and future treatment
.
Current Pharmaceutical Design
vol.
17
,
(
7
)
674
-
684
.
Durham A, Chou P-C, Kirkham P, Adcock IM
(
2010
)
.
Epigenetics in asthma and other inflammatory lung diseases
.
Epigenomics
vol.
2
,
(
4
)
523
-
537
.
Ford PA, Durham AL, Russell REK, Gordon F, Adcock IM, Barnes PJ
(
2010
)
.
Treatment Effects of Low-Dose Theophylline Combined With an Inhaled Corticosteroid in COPD
.
CHEST Journal
vol.
137
,
(
6
)
1338
-
1344
.
Bossé JT, Durham AL, Rycroft AN, Kroll JS, Langford PR
(
2009
)
.
New Plasmid Tools for Genetic Analysis of Actinobacillus pleuropneumoniae and Other Pasteurellaceae
.
Applied and Environmental Microbiology
vol.
75
,
(
19
)
6124
-
6131
.
Adcock IM, Chou P-C, Durham A, Ford P
(
2009
)
.
Overcoming steroid unresponsiveness in airways disease
.
Biochemical Society Transactions
vol.
37
,
(
4
)
824
-
829
.
Williams AS, Issa R, Durham A, Leung S-Y, Kapoun A, Medicherla S, Higgins LS, Adcock IM et al.
(
2008
)
.
Role of p38 mitogen-activated protein kinase in ozone-induced airway hyperresponsiveness and inflammation
.
European Journal of Pharmacology
vol.
600
,
(
1-3
)
117
-
122
.