Publications: Ms Celine Philippe

Philippe C, Mian S, Maniati E, Protopapa P, Bergot T, Piganeau M, Nemkov T, Di Bella D et al. ( 2023 ) . O20 TARGETING THE DEFECTIVE COA PATHWAY TO IMPROVE ERYTHROPOIESIS IN SF3B1-MUTANT MDS-RS PATIENTS . Leukemia Research vol. 128 ,

Woodley K, Dillingh LS, Giotopoulos G, Madrigal P, Rattigan KM, Philippe C, Dembitz V, Magee AMS et al. ( 2023 ) . Mannose metabolism inhibition sensitizes acute myeloid leukaemia cells to therapy by driving ferroptotic cell death . Nature Communications vol. 14 , ( 1 )

Mian SA, Philippe C, Maniati E, Protopapa P, Bergot T, Piganeau M, Nemkov T, Di Bella D et al. ( 2023 ) . Vitamin B5 and succinyl-CoA improve ineffective erythropoiesis in SF3B1-mutated myelodysplasia . Science Translational Medicine vol. 15 , ( 685 ) eabn5135 - eabn5135 .

Berastegui N, Ainciburu M, Romero JP, Garcia-Olloqui P, Alfonso-Pierola A, Philippe C, Vilas-Zornoza A, San Martin-Uriz P et al. ( 2022 ) . The transcription factor DDIT3 is a potential driver of dyserythropoiesis in myelodysplastic syndromes . Nature Communications vol. 13 , ( 1 )

Dembitz V, Lawson H, Philippe C, Burt RJ, James S, Magee ASM, Woodley K, Durko J et al. ( 2022 ) . Inhibition of Stearoyl-CoA Desaturase Has Anti-Leukemic Properties in Acute Myeloid Leukemia . Blood vol. 140 , ( Supplement 1 ) 3058 - 3060 .

Armes H, Bewicke‐Copley F, Rio‐Machin A, Di Bella D, Philippe C, Wozniak A, Tummala H, Wang J et al. ( 2022 ) . Germline ERCC excision repair 6 like 2 (ERCC6L2) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment . British Journal of Haematology vol. 199 , ( 5 ) 754 - 764 .

Woodley K, Dillingh LS, Giotopoulos G, Madrigal P, Tzelepis K, Philippe C, Rattigan K, Asby R et al. ( 2021 ) . Mannose Metabolism Is a Metabolic Vulnerability Unveiled By Standard and Novel Therapies in Acute Myeloid Leukemia . Blood vol. 138 , ( Supplement 1 )

Mian S, Philippe C, Maniati E, Bergot T, Piganeau M, Di Bella D, Morales V, Finch A et al. ( 2021 ) . Vitamin B5 and Succinyl-CoA Improve Ineffective Erythropoiesis in SF3B1 Mutated Myelodysplasia . Blood vol. 138 , ( Supplement 1 )

Féral K, Jaud M, Philippe C, Di Bella D, Pyronnet S, Rouault-Pierre K, Mazzolini L, Touriol C ( 2021 ) . ER Stress and Unfolded Protein Response in Leukemia: Friend, Foe, or Both? . Biomolecules vol. 11 , ( 2 )

Jaud M, Philippe C, Di Bella D, Tang W, Pyronnet S, Laurell H, Mazzolini L, Rouault-Pierre K et al. ( 2020 ) . Translational Regulations in Response to Endoplasmic Reticulum Stress in Cancers . Cells vol. 9 , ( 3 )

Jaud M, Philippe C, Van Den Berghe L, Ségura C, Mazzolini L, Pyronnet S, Laurell H, Touriol C ( 2019 ) . The PERK Branch of the Unfolded Protein Response Promotes DLL4 Expression by Activating an Alternative Translation Mechanism . Cancers vol. 11 , ( 2 )

Bonnet-Magnaval F, Philippe C, Van Den Berghe L, Prats H, Touriol C, Lacazette E ( 2016 ) . Hypoxia and ER stress promote Staufen1 expression through an alternative translation mechanism . Biochemical and Biophysical Research Communications vol. 479 , ( 2 ) 365 - 371 .

Philippe C, Dubrac A, Quelen C, Desquesnes A, Van Den Berghe L, Ségura C, Filleron T, Pyronnet S et al. ( 2016 ) . PERK mediates the IRES-dependent translational activation of mRNAs encoding angiogenic growth factors after ischemic stress . Science Signaling vol. 9 , ( 426 )

Vaysse C, Philippe C, Martineau Y, Quelen C, Hieblot C, Renaud C, Nicaise Y, Desquesnes A et al. ( 2015 ) . Key contribution of eIF4H-mediated translational control in tumor promotion . Oncotarget vol. 6 , ( 37 ) 39924 - 39940 .