Publications: Dr Tanya Soliman

Soliman TN, Keifenheim D, Parker PJ, Clarke DJ ( 2023 ) . Cell cycle responses to Topoisomerase II inhibition: Molecular mechanisms and clinical implications . Journal of Cell Biology vol. 222 , ( 12 )

Lockwood N, Martini S, Lopez-Pardo A, Deiss K, Segeren HA, Semple RK, Collins I, Repana D et al. ( 2022 ) . Genome-protective topoisomerase 2a-dependent G2 arrest requires p53 in hTERT-positive cancer cells . Cancer Research vol. 82 , ( 9 ) 1762 - 1773 .

Watson L, Soliman TN, Davis K, Kelly J, Lockwood N, Yang X, Lynham S, Scott JD et al. ( 2021 ) . Co-ordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention . Biochemical Journal vol. 478 , ( 12 ) 2247 - 2263 .

Kelly JR, Martini S, Brownlow N, Joshi D, Federico S, Jamshidi S, Kjaer S, Lockwood N et al. ( 2020 ) . Author Correction: The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition (Nature Communications, (2020), 11, 1, (1396), 10.1038/s41467-020-15163-6) . Nature Communications vol. 11 , ( 1 )

Parker PJ, Brown SJ, Calleja V, Chakravarty P, Cobbaut M, Linch M, Marshall JJT, Martini S et al. ( 2020 ) . Equivocal, explicit and emergent actions of PKC isoforms in cancer . Nature Reviews Cancer

Parker PJ, Lockwood N, Davis K, Kelly JR, Soliman TN, Pardo AL, Marshall JJT, Redmond JM et al. ( 2020 ) . A cancer-associated, genome protective programme engaging PKCε . Advances in Biological Regulation vol. 78 ,

Mcclelland S, Tamura N, Shaikh N, Muliaditan D, Soliman T, McGuinness J, Maniati E, Moralli D et al. ( 2020 ) . Specific mechanisms of chromosomal instability indicate therapeutic sensitivities in high-grade serous ovarian carcinoma . Cancer Research

Kelly JR, Martini S, Brownlow N, Joshi D, Federico S, Jamshidi S, Kjaer S, Lockwood N et al. ( 2020 ) . The Aurora B specificity switch is required to protect from non-disjunction at the metaphase/anaphase transition . Nature Communications vol. 11 , ( 1 )

Deiss K, Lockwood N, Howell M, Segeren HA, Saunders RE, Chakravarty P, Soliman TN, Martini S et al. ( 2018 ) . A genome-wide RNAi screen identifies the SMC5/6 complex as a non-redundant regulator of a Topo2a-dependent G2 arrest . Nucleic Acids Research vol. 47 , ( 6 ) 2906 - 2921 .

Claus J, Patel G, Autore F, Colomba A, Weitsman G, Soliman TN, Roberts S, Zanetti-Domingues LC et al. ( 2018 ) . Inhibitor-induced HER2-HER3 heterodimerisation promotes proliferation through a novel dimer interface . eLife vol. 7 ,

Martini S, Soliman T, Gobbi G, Mirandola P, Carubbi C, Masselli E, Pozzi G, Parker PJ et al. ( 2018 ) . PKCε Controls Mitotic Progression by Regulating Centrosome Migration and Mitotic Spindle Assembly . Molecular Cancer Research vol. 16 , ( 1 )

Pike T, Brownlow N, Kjaer S, Carlton J, Parker PJ ( 2016 ) . PKCɛ switches Aurora B specificity to exit the abscission checkpoint . Nature Communications vol. 7 , ( 1 )

Brownlow N, Pike T, Zicha D, Collinson L, Parker PJ ( 2014 ) . Mitotic catenation is monitored and resolved by a PKCε-regulated pathway . Nature Communications vol. 5 , ( 1 )

Brownlow N, Pike T, Crossland V, Claus J, Parker P ( 2014 ) . Regulation of the cytokinesis cleavage furrow by PKCε . Biochemical Society Transactions vol. 42 , ( 6 ) 1534 - 1537 .

Pike T, Widberg C, Goodall A, Payne E, Giles N, Hancock J, Gabrielli B ( 2013 ) . Truncated MEK1 is required for transient activation of MAPK signalling in G2 phase cells . Cellular Signalling vol. 25 , ( 6 ) 1423 - 1428 .

Astuti P, Pike T, Widberg C, Payne E, Harding A, Hancock J, Gabrielli B ( 2009 ) . MAPK Pathway Activation Delays G2/M Progression by Destabilizing Cdc25B* . Journal of Biological Chemistry vol. 284 , ( 49 ) 33781 - 33788 .

Loh K, Chia JA, Greco S, Cozzi S, Buttenshaw RL, Bond CE, Simms LA, Pike T et al. ( 2008 ) . Bone morphogenic protein 3 inactivation is an early and frequent event in colorectal cancer development . Genes Chromosomes and Cancer vol. 47 , ( 6 ) 449 - 460 .

Spring KJ, Zhao ZZ, Karamatic R, Walsh MD, Whitehall VLJ, Pike T, Simms LA, Young J et al. ( 2006 ) . High Prevalence of Sessile Serrated Adenomas With BRAF Mutations: A Prospective Study of Patients Undergoing Colonoscopy . Gastroenterology vol. 131 , ( 5 ) 1400 - 1407 .