Publications:   Ioanna Keklikoglou

Martinez-Usatorre A, Kadioglu E, Cianciaruso C, Torchia B, Faget J, Meylan E, Schmittnaegel M, Keklikoglou I et al.(2020). O4 Mechanisms of lung cancer hyper-progression promoted by PD-1 immune checkpoint blockade. Journal for ImmunoTherapy of Cancer vol. 8, (Suppl 2) a5.1-a5a5.

Keklikoglou I, Cianciaruso C, Güç E, Squadrito ML, Spring LM, Tazzyman S, Lambein L, Poissonnier A et al.(2019). Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nature Cell Biology vol. 21, (2) 190-202.

Keklikoglou I, Kadioglu E, Bissinger S, Langlois B, Bellotti A, Orend G, Ries CH, De Palma M(2018). Periostin Limits Tumor Response to VEGFA Inhibition. Cell Reports vol. 22, (10) 2530-2540.

Bissinger S, Schmittnaegel M, Keklikoglou I, De Palma M, Hoves S, Ries C (2017). CSF1/CSF1R signaling blockade triggers release of matrix-degrading proteases in mouse models. JOURNAL FOR IMMUNOTHERAPY OF CANCER. vol. 5,

Keklikoglou I, Hosaka K, Bender C, Bott A, Koerner C, Mitra D, Will R, Woerner A et al.(2015). MicroRNA-206 functions as a pleiotropic modulator of cell proliferation, invasion and lymphangiogenesis in pancreatic adenocarcinoma by targeting ANXA2 and KRAS genes. Oncogene vol. 34, (37) 4867-4878.

Hughes R, Qian BZ, Rowan C, Muthana M, Keklikoglou I, Olson OC, Tazzyman S, Danson S et al.(2015). Perivascular M2 macrophages stimulate tumor relapse after chemotherapy. Cancer Research vol. 75, (17) 3479-3491.

Russell H, Qian B, Keklikoglou I, Oakley O, Muthana M, De Palma M, Joyce J, Pollard J et al. (2015). A distinct subset of perivascular macrophages drive tumour relapse after chemotherapy. CLINICAL & EXPERIMENTAL METASTASIS. vol. 32, 184-184.

Shukla K, Sharma AK, Ward A, Will R, Hielscher T, Balwierz A, Breunig C, Münstermann E et al.(2015). MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer. Molecular Oncology vol. 9, (6) 1106-1119.

Keklikoglou I, De Palma M(2014). Cancer: Metastasis risk after anti-macrophage therapy. Nature vol. 515, (7525) 46-47.

Rigamonti N, Kadioglu E, Keklikoglou I, Rmili CW, Leow CC, de Palma M(2014). Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade. Cell Reports vol. 8, (3) 696-706.

Wiemann S, Bott A, Keklikoglou I, Giacomelli C, Balwierz A, Uhlmann S, Mannsperger H, Korf U et al. (2014). 53: miRNA-protein interaction networks in cancer. European Journal of Cancer. vol. 50,

Keklikoglou I, De Palma M(2014). Vascular modulatory functions of macrophages. Macrophages: Biology and Role in the Pathology of Diseases,

Keklikoglou I, Ward A(2014). MIR373 (microRNA 373). Atlas of Genetics and Cytogenetics in Oncology and Haematology (3)

Wiemann S, Keklikoglou I, Uhlmann S, Giacomelli C, Mannsperger H, Korf U(2014). SP-0606: miRNA-protein interaction networks in cancer. Radiotherapy and Oncology vol. 111,

Garding A, Bhattacharya N, Claus R, Ruppel M, Tschuch C, Filarsky K, Idler I, Zucknick M et al.(2013). Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB. PLoS Genetics vol. 9, (4)

Körner C, Keklikoglou I, Bender C, Wörner A, Münstermann E, Wiemann S(2013). MicroRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C ε (PKCε). Journal of Biological Chemistry vol. 288, (12) 8750-8761.

Keklikoglou I, Koerner C, Schmidt C, Zhang JD, Heckmann D, Shavinskaya A, Allgayer H, Gückel B et al.(2012). MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-B and TGF-Β signaling pathways. Oncogene vol. 31, (37) 4150-4163.

Mertens D, Bhattacharya N, Garding A, Claus R, Zucknick M, Filarsky K, Keklikoglou I, Idler I et al. (2012). EPIGENETIC UPREGULATION OF LNCRNAS AT 13Q14.3 IN LEUKEMIA CORRELATES WITH DOWNREGULATION IN CIS OF A GENE CLUSTER REGULATING NF-KB. HAEMATOLOGICA. vol. 97, 450-450.

Jurmeister S, Baumann M, Balwierz A, Keklikoglou I, Ward A, Uhlmann S, Zhang JD, Wiemann S et al.(2012). MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. Molecular and Cellular Biology vol. 32, (3) 633-651.

Gorska K, Keklikoglou I, Tschulena U, Winssinger N(2011). Rapid fluorescence imaging of miRNAs in human cells using templated Staudinger reaction. Chemical Science vol. 2, (10) 1969-1975.

Zhang JD, Koerner C, Bechtel S, Bender C, Keklikoglou I, Schmidt C, Irsigler A, Ernst U et al.(2011). Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation. PLoS ONE vol. 6, (7)

Tschulena U, Keklikoglou I, Horwedel C, Zhang D, Diederichs S, Wiemann S (2010). 684 A novel large-scale screen to identify modulators of oncomir miR-21. European Journal of Cancer Supplements. vol. 8,

Arrizubieta MJ, Kanata E, Keklikoglou I, Papasavva-Stylianou P, Toumazos P, Panagiotidis CH, Sklaviadis T(2009). Design and validation of a high-throughput assay to detect codon 146 polymorphisms in the caprine prion protein gene. Analytical Biochemistry vol. 393, (2) 229-233.