Publications:   Ioanna Keklikoglou

Keklikoglou I, Cianciaruso C, Güç E, Squadrito ML, Spring LM, Tazzyman S, Lambein L, Poissonnier A et al.(2019). Chemotherapy elicits pro-metastatic extracellular vesicles in breast cancer models. Nature Cell Biology vol. 21, (2) 190-202.

Keklikoglou I, Kadioglu E, Bissinger S, Langlois B, Bellotti A, Orend G, Ries CH, De Palma M(2018). Periostin Limits Tumor Response to VEGFA Inhibition. Cell Reports vol. 22, (10) 2530-2540.

Bissinger S, Schmittnaegel M, Keklikoglou I, De Palma M, Hoves S, Ries C (2017). CSF1/CSF1R signaling blockade triggers release of matrix-degrading proteases in mouse models. JOURNAL FOR IMMUNOTHERAPY OF CANCER. vol. 5,

Keklikoglou I, Hosaka K, Bender C, Bott A, Koerner C, Mitra D, Will R, Woerner A et al.(2015). MicroRNA-206 functions as a pleiotropic modulator of cell proliferation, invasion and lymphangiogenesis in pancreatic adenocarcinoma by targeting ANXA2 and KRAS genes. Oncogene vol. 34, (37) 4867-4878.

Hughes R, Qian BZ, Rowan C, Muthana M, Keklikoglou I, Olson OC, Tazzyman S, Danson S et al.(2015). Perivascular M2 macrophages stimulate tumor relapse after chemotherapy. Cancer Research vol. 75, (17) 3479-3491.

Russell H, Qian B, Keklikoglou I, Oakley O, Muthana M, De Palma M, Joyce J, Pollard J et al. (2015). A distinct subset of perivascular macrophages drive tumour relapse after chemotherapy. CLINICAL & EXPERIMENTAL METASTASIS. vol. 32, 184-184.

Shukla K, Sharma AK, Ward A, Will R, Hielscher T, Balwierz A, Breunig C, Münstermann E et al.(2015). MicroRNA-30c-2-3p negatively regulates NF-κB signaling and cell cycle progression through downregulation of TRADD and CCNE1 in breast cancer. Molecular Oncology vol. 9, (6) 1106-1119.

Keklikoglou I, De Palma M(2014). Cancer: Metastasis risk after anti-macrophage therapy. Nature vol. 515, (7525) 46-47.

Rigamonti N, Kadioglu E, Keklikoglou I, Rmili CW, Leow CC, de Palma M(2014). Role of angiopoietin-2 in adaptive tumor resistance to VEGF signaling blockade. Cell Reports vol. 8, (3) 696-706.

Wiemann S, Bott A, Keklikoglou I, Giacomelli C, Balwierz A, Uhlmann S, Mannsperger H, Korf U et al. (2014). miRNA-protein interaction networks in cancer. EUROPEAN JOURNAL OF CANCER. vol. 50, S13-S13.

Keklikoglou I, De Palma M(2014). Vascular modulatory functions of macrophages. Macrophages: Biology and Role in the Pathology of Diseases,

Garding A, Bhattacharya N, Claus R, Ruppel M, Tschuch C, Filarsky K, Idler I, Zucknick M et al.(2013). Epigenetic Upregulation of lncRNAs at 13q14.3 in Leukemia Is Linked to the In Cis Downregulation of a Gene Cluster That Targets NF-kB. PLoS Genetics vol. 9, (4)

Körner C, Keklikoglou I, Bender C, Wörner A, Münstermann E, Wiemann S(2013). MicroRNA-31 sensitizes human breast cells to apoptosis by direct targeting of protein kinase C ε (PKCε). Journal of Biological Chemistry vol. 288, (12) 8750-8761.

Keklikoglou I, Koerner C, Schmidt C, Zhang JD, Heckmann D, Shavinskaya A, Allgayer H, Gückel B et al.(2012). MicroRNA-520/373 family functions as a tumor suppressor in estrogen receptor negative breast cancer by targeting NF-B and TGF-Β signaling pathways. Oncogene vol. 31, (37) 4150-4163.

Jurmeister S, Baumann M, Balwierz A, Keklikoglou I, Ward A, Uhlmann S, Zhang JD, Wiemann S et al.(2012). MicroRNA-200c represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. Molecular and Cellular Biology vol. 32, (3) 633-651.

Gorska K, Keklikoglou I, Tschulena U, Winssinger N(2011). Rapid fluorescence imaging of miRNAs in human cells using templated Staudinger reaction. Chemical Science vol. 2, (10) 1969-1975.

Zhang JD, Koerner C, Bechtel S, Bender C, Keklikoglou I, Schmidt C, Irsigler A, Ernst U et al.(2011). Time-resolved human kinome RNAi screen identifies a network regulating mitotic-events as early regulators of cell proliferation. PLoS ONE vol. 6, (7)

Tschulena U, Keklikoglou I, Horwedel C, Zhang D, Diederichs S, Wiemann S (2010). A novel large-scale screen to identify modulators of oncomir miR-21. EJC SUPPLEMENTS. vol. 8, 172-172.

Arrizubieta MJ, Kanata E, Keklikoglou I, Papasavva-Stylianou P, Toumazos P, Panagiotidis CH, Sklaviadis T(2009). Design and validation of a high-throughput assay to detect codon 146 polymorphisms in the caprine prion protein gene. Analytical Biochemistry vol. 393, (2) 229-233.