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Research

Publications: Dr Deepti Gurdasani

Gurdasani D, Akrami A, Bradley VC, Costello A, Greenhalgh T, Flaxman S, McKee M, Michie S et al. ( 2022 ) . Long COVID in children . The Lancet Child and Adolescent Health vol. 6 , ( 1 )
Ziauddeen H, Subramaniam N, Gurdasani D ( 2021 ) . Modelling the impact of lockdown-easing measures on cumulative COVID-19 cases and deaths in England . BMJ Open vol. 11 , ( 9 )
Gurdasani D, Drury J, Greenhalgh T, Griffin S, Haque Z, Hyde Z, Katzourakis A, McKee M et al. ( 2021 ) . Mass infection is not an option: we must do more to protect our young . The Lancet vol. 398 , ( 10297 ) 297 - 298 .
Gurdasani D, Alwan NA, Greenhalgh T, Hyde Z, Johnson L, McKee M, Michie S, Prather KA et al. ( 2021 ) . School reopening without robust COVID-19 mitigation risks accelerating the pandemic . The Lancet vol. 397 , ( 10280 ) 1177 - 1178 .
Gurdasani D, Bear L, Bogaert D, Burgess RA, Busse R, Cacciola R, Charpak Y, Colbourn T et al. ( 2020 ) . The UK needs a sustainable strategy for COVID-19 . The Lancet vol. 396 , ( 10265 ) 1800 - 1801 .
Sallah N, Miley W, Labo N, Carstensen T, Fatumo S, Gurdasani D, Pollard MO, Dilthey AT et al. ( 2020 ) . Distinct genetic architectures and environmental factors associate with host response to the γ2-herpesvirus infections . Nature Communications vol. 11 , ( 1 )
Alwan NA, Burgess RA, Ashworth S, Beale R, Bhadelia N, Bogaert D, Dowd J, Eckerle I et al. ( 2020 ) . Scientific consensus on the COVID-19 pandemic: we need to act now . The Lancet vol. 396 , ( 10260 ) e71 - e72 .
Gurdasani D, Ziauddeen H ( 2020 ) . On the fallibility of simulation models in informing pandemic responses . The Lancet Global Health vol. 8 , ( 6 ) e776 - e777 .
Mathieson I, Abascal F, Vinner L, Skoglund P, Pomilla C, Mitchell P, Arthur C, Gurdasani D et al. ( 2020 ) . An ancient baboon genome demonstrates long-term population continuity in Southern Africa . Genome Biology and Evolution vol. 12 , ( 4 ) 407 - 412 .
Kuchenbaecker K, Telkar N, Reiker T, Walters RG, Lin K, Eriksson A, Gurdasani D, Gilly A et al. ( 2019 ) . The transferability of lipid loci across African, Asian and European cohorts . Nature Communications vol. 10 , ( 1 )
Gurdasani D, Carstensen T, Fatumo S, Chen G, Franklin CS, Prado-Martinez J, Bouman H, Abascal F et al. ( 2019 ) . Uganda Genome Resource Enables Insights into Population History and Genomic Discovery in Africa . Cell vol. 179 , ( 4 ) 984 - 1002.e36 .
Lule SA, Mentzer AJ, Namara B, Muwenzi AG, Nassanga B, kizito D, Akurut H, Lubyayi L et al. ( 2019 ) . A genome-wide association and replication study of blood pressure in Ugandan early adolescents . Molecular Genetics and Genomic Medicine vol. 7 , ( 10 )
Muriuki JM, Mentzer AJ, Band G, Gilchrist JJ, Carstensen T, Lule SA, Goheen MM, Joof F et al. ( 2019 ) . The ferroportin Q248H mutation protects from anemia, but not malaria or bacteremia . Science Advances vol. 5 , ( 9 )
Gurdasani D, Barroso I, Zeggini E, Sandhu MS ( 2019 ) . Author Correction: Genomics of disease risk in globally diverse populations (Nature Reviews Genetics, (2019), 20, 9, (520-535), 10.1038/s41576-019-0144-0) . Nature Reviews Genetics vol. 20 , ( 9 )
Gurdasani D, Barroso I, Zeggini E, Sandhu MS ( 2019 ) . Genomics of disease risk in globally diverse populations . Nature Reviews Genetics vol. 20 , ( 9 ) 520 - 535 .
Kuchenbaecker K, Reiker T, Gilly A, Gurdasani D, Prins B, Suveges D, Southam L, Asiki G et al. ( 2019 ) . Associations of polygenic scores with lipid biomarkers in diverse populations . EUROPEAN JOURNAL OF HUMAN GENETICS . vol. 27 , 856 - 857 .
Kuchenbaecker K, Reiker T, Gilly A, Gurdasani D, Southam L, Asiki G, Seeley J, Kamali A et al. ( 2019 ) . 28GENETIC ASSOCIATION ANALYSES IN DIVERSE ANCESTRY POPULATIONS . European Neuropsychopharmacology . vol. 29 ,
Fatumo S, Carstensen T, Nashiru O, Gurdasani D, Sandhu M, Kaleebu P ( 2019 ) . Complimentary methods for multivariate genome-wide association study identify new susceptibility genes for blood cell traits . Frontiers in Genetics vol. 10 , ( APR )
Pollard MO, Gurdasani D, Mentzer AJ, Porter T, Sandhu MS ( 2018 ) . Long reads: Their purpose and place . Human Molecular Genetics vol. 27 , ( R2 ) R234 - R241 .
Thorne L, Nalwoga A, Mentzer AJ, De Rougemont A, Hosmillo M, Webb E, Nampiija M, Muhwezi A et al. ( 2018 ) . The first norovirus longitudinal seroepidemiological study from sub-Saharan Africa reveals high seroprevalence of diverse genotypes associated with host susceptibility factors . Journal of Infectious Diseases vol. 218 , ( 5 ) 716 - 725 .
Partap U, Allcock SH, Parker E, Gurdasani D, Young EH, Sandhu MS ( 2018 ) . Association between early life antibiotic use and childhood overweight and obesity: a narrative review . Global health, epidemiology and genomics vol. 3 ,
Ekoru K, Young EH, Dillon DG, Gurdasani D, Stehouwer N, Faurholt-Jepsen D, Levitt NS, Crowther NJ et al. ( 2018 ) . HIV treatment is associated with a twofold higher probability of raised triglycerides: Pooled analyses in 21 023 individuals in sub-Saharan Africa . Global Health, Epidemiology and Genomics vol. 3 ,
McLaren PJ, Pulit SL, Gurdasani D, Bartha I, Shea PR, Pomilla C, Gupta N, Gkrania-Klotsas E et al. ( 2017 ) . Evaluating the impact of functional genetic variation on HIV-1 Control . Journal of Infectious Diseases vol. 216 , ( 9 ) 1063 - 1069 .
Lin M, Granka JM, Martin AR, Myrick J, Atkinson EG, Werely CJ, Gurdasani D, Pomilla C et al. ( 2017 ) . High Heritability and Ancestry Dominance are behind the Genetics of Short Stature in South African KhoeSan Populations . AMERICAN JOURNAL OF PHYSICAL ANTHROPOLOGY . vol. 162 , 263 - 264 .
Allcock S, Young EH, Holmes M, Gurdasani D, Dougan G, Sandhu MS, Solomon L, Török ME ( 2017 ) . Antimicrobial resistance in human populations: Challenges and opportunities . Global Health, Epidemiology and Genomics vol. 2 ,
Allcock S, Young EH, Holmes M, Gurdasani D, Dougan G, Sandhu MS, Solomon L, Török ME ( 2017 ) . Erratum: Antimicrobial resistance in human populations: challenges and opportunities - ERRATUM . Global health, epidemiology and genomics vol. 2 ,
Telkar N, Reiker T, Walters RG, Lin K, Eriksson A, Gurdasani D, Gilly A, Southam L et al. ( 2017 ) . The Transferability of Lipid-Associated Loci Across African, Asian and European Cohorts . HUMAN HEREDITY . vol. 83 , 237 - 237 .
Sallah N, Carstensen T, Wakeham K, Bagni R, Labo N, Pollard MO, Gurdasani D, Ekoru K et al. ( 2017 ) . Whole-genome association study of antibody response to Epstein-Barr virus in an African population: a pilot . Global health, epidemiology and genomics vol. 2 ,
Dillon DG ( 2016 ) . Association of HIV and ART with cardiometabolic traits in sub-Saharan Africa: a systematic review and meta-analysis . Int J Epidemiol vol. 45 , ( 6 ) 2210 - 2211 .
Sallah N, Carstensen T, Wakeham K, Bagni R, Labo N, Pollard MO, Gurdasani D, Ekoru K et al. ( 2016 ) . Novel Genome-Wide Sequence Variants Influence Antibody Response to Epstein-Barr Virus in an African Population . GENETIC EPIDEMIOLOGY . vol. 40 , 618 - 618 .
Heckerman D, Gurdasani D, Kadie C, Pomilla C, Carstensen T, Martin H, Ekoru K, Nsubuga RN et al. ( 2016 ) . Linear mixed model for heritability estimation that explicitly addresses environmental variation . Proceedings of the National Academy of Sciences of the United States of America vol. 113 , ( 27 ) 7377 - 7382 .
McLaren PJ, Coulonges C, Bartha I, Lenz TL, Deutsch AJ, Bashirova A, Buchbinder S, Carrington MN et al. ( 2015 ) . Polymorphisms of large effect explain the majority of the host genetic contribution to variation of HIV-1 virus load . Proceedings of the National Academy of Sciences of the United States of America vol. 112 , ( 47 ) 14658 - 14663 .
Pagani L, Schiffels S, Gurdasani D, Danecek P, Scally A, Chen Y, Xue Y, Haber M et al. ( 2015 ) . Tracing the Route of Modern Humans out of Africa by Using 225 Human Genome Sequences from Ethiopians and Egyptians . American Journal of Human Genetics vol. 96 , ( 6 ) 986 - 991 .
Gurdasani D, Carstensen T, Tekola-Ayele F, Pagani L, Tachmazidou I, Hatzikotoulas K, Karthikeyan S, Iles L et al. ( 2015 ) . The African Genome Variation Project shapes medical genetics in Africa . Nature vol. 517 , ( 7534 ) 327 - 332 .
Olson AD, Meyer L, Prins M, Thiebaut R, Gurdasani D, Guiguet M, Chaix ML, Amornkul P et al. ( 2014 ) . An evaluation of HIV elite controller definitions within a large seroconverter cohort collaboration . PLoS ONE vol. 9 , ( 1 )
Gurdasani D, Iles L, Dillon DG, Young EH, Olson AD, Naranbhai V, Fidler S, Gkrania-Klotsas E et al. ( 2014 ) . A systematic review of definitions of extreme phenotypes of HIV control and progression . AIDS vol. 28 , ( 2 ) 149 - 162 .
O'Connell J, Gurdasani D, Delaneau O, Pirastu N, Ulivi S, Cocca M, Traglia M, Huang J et al. ( 2014 ) . A General Approach for Haplotype Phasing across the Full Spectrum of Relatedness . PLoS Genetics vol. 10 , ( 4 )
Ye Z, Haycock PC, Gurdasani D, Pomilla C, Boekholdt SM, Tsimikas S, Khaw KT, Wareham NJ et al. ( 2014 ) . The association between circulating lipoprotein(a) and type 2 diabetes: Is it causal? . Diabetes vol. 63 , ( 1 ) 332 - 342 .
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S et al. ( 2013 ) . Common variants associated with plasma triglycerides and risk for coronary artery disease . Nature Genetics vol. 45 , ( 11 ) 1345 - 1353 .
Global Lipids Genetics Consortium, Willer CJ, Schmidt EM, Sengupta S, Peloso GM, Gustafsson S, Kanoni S, Ganna A et al. ( 2013 ) . Discovery and refinement of loci associated with lipid levels . Nat Genet vol. 45 , ( 11 ) 1274 - 1283 .
Dillon DG, Gurdasani D, Riha J, Ekoru K, Asiki G, Mayanja BN, Levitt NS, Crowther NJ et al. ( 2013 ) . Association of HIV and ART with cardiometabolic traits in sub-Saharan Africa: A systematic review and meta-analysis . International Journal of Epidemiology vol. 42 , ( 6 ) 1754 - 1771 .
Do R, Willer CJ, Schmidt EM, Sengupta S, Gao C, Peloso GM, Gustafsson S, Kanoni S et al. ( 2013 ) . Common variants associated with plasma triglycerides and risk for coronary artery disease . Nature Genetics
Gurdasani D, Sjouke B, Tsimikas S, Hovingh GK, Luben RN, Wainwright NWJ, Pomilla C, Wareham NJ et al. ( 2012 ) . Lipoprotein(a) and risk of coronary, cerebrovascular, and peripheral artery disease: The EPIC-norfolk prospective population study . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 32 , ( 12 ) 3058 - 3065 .
Manson AL, Gurugama P, Colston J, Gurdasani D, Sandhu MS, Breuer J, Seneviratne SL ( 2011 ) . Familial recurrent herpes-simplex type 1 infection: an approach to characterise the molecular basis . IMMUNOLOGY . vol. 135 , 162 - 162 .
Gurdasani D, Surendrababu NRS, Paul TV ( 2008 ) . An interesting case of hypogonadism . Hong Kong Medical Journal vol. 14 , ( 3 ) 244 - 245 .
Paul TV, Gurdasani D, Spurgeon R ( 2008 ) . Visual vignette . Endocrine Practice vol. 14 , ( 2 )