Publications: Dr Miguel Ganuza Fernandez
Gorur V, Kranc KR, Ganuza M, Telfer P
(
2023
)
.
Haematopoietic stem cell health in sickle cell disease and its implications for stem cell therapies and secondary haematological disorders
.
Blood Reviews
vol.
63
,
Ganuza M, Hall T, Myers J, Nevitt C, Sánchez-Lanzas R, Chabot A, Ding J, Kooienga E et al.
(
2022
)
.
Murine foetal liver supports limited detectable expansion of life-long haematopoietic progenitors
.
Nature Cell Biology
vol.
24
,
(
10
)
1475
-
1486
.
Bogeska R, Mikecin A-M, Kaschutnig P, Fawaz M, Büchler-Schäff M, Le D, Ganuza M, Vollmer A et al.
(
2022
)
.
Inflammatory exposure drives long-lived impairment of hematopoietic stem cell self-renewal activity and accelerated aging
.
Cell Stem Cell
vol.
29
,
(
8
)
1273
-
1284.e8
.
Sánchez‐Lanzas R, Kalampalika F, Ganuza M
(
2022
)
.
Diversity in the bone marrow niche: Classic and novel strategies to uncover niche composition
.
British Journal of Haematology
vol.
199
,
(
5
)
647
-
664
.
Ganuza M, Clements W, McKinney-Freeman S
(
2021
)
.
Specification of hematopoietic stem cells in mammalian embryos: a rare or frequent event?
.
Blood
vol.
140
,
(
4
)
309
-
320
.
Ganuza M, Hall T, Obeng EA, McKinney-Freeman S
(
2020
)
.
Clones assemble! The clonal complexity of blood during ontogeny and disease
.
Experimental Hematology
vol.
83
,
35
-
47
.
Ganuza M, Hall T, Finkelstein D, Wang Y-D, Chabot A, Kang G, Bi W, Wu G et al.
(
2019
)
.
The global clonal complexity of the murine blood system declines throughout life and after serial transplantation
.
Blood
vol.
133
,
(
18
)
1927
-
1942
.
Ganuza M, Chabot A, Tang X, Bi W, Natarajan S, Carter R, Gawad C, Kang G et al.
(
2018
)
.
Murine hematopoietic stem cell activity is derived from pre-circulation embryos but not yolk sacs
.
Nature Communications
vol.
9
,
(
1
)
5405
-
5405
.
Hall T, Walker M, Ganuza M, Holmfeldt P, Bordas M, Kang G, Bi W, Palmer LE et al.
(
2018
)
.
Nfix Promotes Survival of Immature Hematopoietic Cells via Regulation of c-Mpl
.
Stem Cells
vol.
36
,
(
6
)
943
-
950
.
Ganuza M, Hall T, Finkelstein D, Chabot A, Kang G, McKinney-Freeman S
(
2017
)
.
Lifelong haematopoiesis is established by hundreds of precursors throughout mammalian ontogeny
.
Nature Cell Biology
vol.
19
,
(
10
)
1153
-
1163
.
Ganuza M, McKinney-Freeman S
(
2017
)
.
Hematopoietic stem cells under pressure
.
Curr Opin Hematol
vol.
24
,
(
4
)
314
-
321
.
Ganuza M, Hadland B, Chabot A, Li C, Kang G, Bernstein I, McKinney-Freeman S
(
2017
)
.
Murine hemogenic endothelial precursors display heterogeneous hematopoietic potential ex vivo
.
Experimental Hematology
vol.
51
,
25
-
35.e6
.
Holmfeldt P, Ganuza M, Marathe H, He B, Hall T, Kang G, Moen J, Pardieck J et al.
(
2016
)
.
Correction: Functional screen identifies regulators of murine hematopoietic stem cell repopulation
.
Journal of Experimental Medicine
vol.
213
,
(
11
)
2525
-
2525
.
Holmfeldt P, Ganuza M, Marathe H, He B, Hall T, Kang G, Moen J, Pardieck J et al.
(
2016
)
.
Functional screen identifies regulators of murine hematopoietic stem cell repopulation
.
Journal of Experimental Medicine
vol.
213
,
(
3
)
433
-
449
.
Fernandez MG, Holmfeldt P, Marathe H, Hall T, Pardieck J, McKinney-Freeman S
(
2014
)
.
Functional Screen Identifies Novel Regulators of Murine Hematopoietic Stem Cell Engraftment
.
Blood
vol.
124
,
(
21
)
Ganuza M, Santamaría D
(
2012
)
.
Cdk7: Open questions beyond the prevailing model
.
Cell Cycle
vol.
11
,
(
19
)
3519
-
3520
.
Ganuza M, Sáiz‐Ladera C, Cañamero M, Gómez G, Schneider R, Blasco MA, Pisano D, Paramio JM et al.
(
2012
)
.
Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion
.
The EMBO Journal
vol.
31
,
(
11
)
2498
-
2510
.