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Publications:  Dr Helen Rowe

Gale Hammell M, Rowe HM(2020). Editorial Overview: Endogenous Retroviruses in Development and Disease. Viruses vol. 12, (12) 1446-1446.
Tunbak H, Enriquez-Gasca R, Tie CHC, Gould PA, Mlcochova P, Gupta RK, Fernandes L, Holt J et al.(2020). The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s. Nature Communications vol. 11, (1)
Enriquez-Gasca R, Gould PA, Rowe HM(2020). Host gene regulation by transposable elements: The new, the old and the ugly. Viruses vol. 12, (10)
Gould PA, Rowe HM(2019). A nuclear licence to silence transposons. EMBO reports vol. 20, (12)
Tie CHC, Fernandes L, Conde L, Robbez¿Masson L, Sumner RP, Peacock T, Rodriguez¿Plata MT, Mickute G et al.(2018). KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control. EMBO Reports vol. 19, (10)
Robbez-Masson L, Tie CHC, Conde L, Tunbak H, Husovsky C, Tchasovnikarova IA, Timms RT, Herrero J et al.(2018). The hush complex cooperates with trim28 to repress young retrotransposons and new genes. Genome Research vol. 28, (6) 836-845.
Smith-Moore S, Neil SJD, Fraefel C, Linden RM, Bollen M, Rowe HM, Henckaerts E(2018). Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome. Proceedings of the National Academy of Sciences vol. 115, (15) E3529-E3538.
Robbez-Masson L, Tie CHC, Rowe HM(2017). Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!. Journal of Cell Biology vol. 216, (11) 3429-3431.
Tie CH, Rowe HM(2017). Epigenetic control of retrotransposons in adult tissues: implications for immune regulation. Curr Opin Virol vol. 25, 28-33.
Ecco G, Cassano M, Kauzlaric A, Duc J, Coluccio A, Offner S, Imbeault M, Rowe HM et al.(2016). Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues. Dev Cell vol. 36, (6) 611-623.
Robbez-Masson L, Rowe HM(2015). Retrotransposons shape species-specific embryonic stem cell gene expression. Retrovirology vol. 12,
Friedli M, Turelli P, Kapopoulou A, Rauwel B, Castro-Díaz N, Rowe HM, Ecco G, Unzu C et al.(2014). Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency. Genome Res vol. 24, (8) 1251-1259.
Rowe HM, Kapopoulou A, Corsinotti A, Fasching L, Macfarlan TS, Tarabay Y, Viville S, Jakobsson J et al.(2013). TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells. Genome Res vol. 23, (3) 452-461.
Rowe HM, Friedli M, Offner S, Verp S, Mesnard D, Marquis J, Aktas T, Trono D(2013). De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET. Development vol. 140, (3) 519-529.
Corsinotti A, Kapopoulou A, Gubelmann C, Imbeault M, Santoni de Sio FR, Rowe HM, Mouscaz Y, Deplancke B et al.(2013). Global and stage specific patterns of Krüppel-associated-box zinc finger protein gene expression in murine early embryonic cells. PLoS One vol. 8, (2)
Macfarlan TS, Gifford WD, Driscoll S, Lettieri K, Rowe HM, Bonanomi D, Firth A, Singer O et al.(2012). Embryonic stem cell potency fluctuates with endogenous retrovirus activity. Nature vol. 487, (7405) 57-63.
Rowe HM, Trono D(2011). Dynamic control of endogenous retroviruses during development. Virology vol. 411, (2) 273-287.
Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H et al.(2010). KAP1 controls endogenous retroviruses in embryonic stem cells. Nature vol. 463, (7278) 237-240.
Arce F, Rowe HM, Chain B, Lopes L, Collins MK(2009). Lentiviral vectors transduce proliferating dendritic cell precursors leading to persistent antigen presentation and immunization. Molecular Therapy vol. 17, (9) 1643-1650.
Rowe HM, Lopes L, Brown N, Efklidou S, Smallie T, Karrar S, Kaye PM, Collins MK(2009). Expression of vFLIP in a lentiviral vaccine vector activates NF-{kappa}B, matures dendritic cells, and increases CD8+ T-cell responses. Journal of Virology vol. 83, (4) 1555-1562.
Rowe HM, Lopes L, Ikeda Y, Bailey R, Barde I, Zenke M, Chain BM, Collins MK(2006). Immunization with a lentiviral vector stimulates both CD4 and CD8 T cell responses to an ovalbumin transgene. Mol Ther vol. 13, (2) 310-319.
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