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Publications:  Dr Helen Rowe

Gould PA, Rowe HM(2019). A nuclear licence to silence transposons. EMBO reports vol. 20, (12)
10.15252/embr.201949262
https://qmro.qmul.ac.uk/xmlui/handle/123456789/65000
Tie CHC, Fernandes L, Conde L, Robbez¿Masson L, Sumner RP, Peacock T, Rodriguez¿Plata MT, Mickute G et al.(2018). KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control. EMBO Reports vol. 19, (10)
10.15252/embr.201745000
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63763
Robbez-Masson L, Tie CHC, Conde L, Tunbak H, Husovsky C, Tchasovnikarova IA, Timms RT, Herrero J et al.(2018). The hush complex cooperates with trim28 to repress young retrotransposons and new genes. Genome Research vol. 28, (6) 836-845.
10.1101/gr.228171.117
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63770
Smith-Moore S, Neil SJD, Fraefel C, Linden RM, Bollen M, Rowe HM, Henckaerts E(2018). Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome. Proceedings of the National Academy of Sciences vol. 115, (15) E3529-E3538.
10.1073/pnas.1721883115
https://qmro.qmul.ac.uk/xmlui/handle/123456789/63759
Robbez-Masson L, Tie CHC, Rowe HM(2017). Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!. Journal of Cell Biology vol. 216, (11) 3429-3431.
10.1083/jcb.201710068
Tie CHC, Rowe HM(2017). Epigenetic control of retrotransposons in adult tissues: implications for immune regulation. Current Opinion in Virology vol. 25, 28-33.
10.1016/j.coviro.2017.06.007
Ecco G, Cassano M, Kauzlaric A, Duc J, Coluccio A, Offner S, Imbeault M, Rowe HM et al.(2016). Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues. Developmental Cell vol. 36, (6) 611-623.
10.1016/j.devcel.2016.02.024
Robbez-Masson L, Rowe HM(2015). Retrotransposons shape species-specific embryonic stem cell gene expression. Retrovirology vol. 12, (1) Article 45,
10.1186/s12977-015-0173-5
Friedli M, Turelli P, Kapopoulou A, Rauwel B, Castro-Díaz N, Rowe HM, Ecco G, Unzu C et al.(2014). Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency. Genome Research vol. 24, (8) 1251-1259.
10.1101/gr.172809.114
Corsinotti A, Kapopoulou A, Gubelmann C, Imbeault M, Santoni de Sio FR, Rowe HM, Mouscaz Y, Deplancke B et al.(2013). Global and Stage Specific Patterns of Krüppel-Associated-Box Zinc Finger Protein Gene Expression in Murine Early Embryonic Cells. PLoS ONE vol. 8, (2) e56721-e56721.
10.1371/journal.pone.0056721
Rowe HM, Friedli M, Offner S, Verp S, Mesnard D, Marquis J, Aktas T, Trono D(2013). De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET. Development vol. 140, (3) 519-529.
10.1242/dev.087585
Rowe HM, Kapopoulou A, Corsinotti A, Fasching L, Macfarlan TS, Tarabay Y, Viville S, Jakobsson J et al.(2012). TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells. Genome Research vol. 23, (3) 452-461.
10.1101/gr.147678.112
Macfarlan TS, Gifford WD, Driscoll S, Lettieri K, Rowe HM, Bonanomi D, Firth A, Singer O et al.(2012). Embryonic stem cell potency fluctuates with endogenous retrovirus activity. Nature vol. 487, (7405) 57-63.
10.1038/nature11244
Rowe HM, Trono D(2011). Dynamic control of endogenous retroviruses during development. Virology vol. 411, (2) 273-287.
10.1016/j.virol.2010.12.007
Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H et al.(2010). KAP1 controls endogenous retroviruses in embryonic stem cells. Nature vol. 463, (7278) 237-240.
10.1038/nature08674
Arce F, Rowe HM, Chain B, Lopes L, Collins MK(2009). Lentiviral Vectors Transduce Proliferating Dendritic Cell Precursors Leading to Persistent Antigen Presentation and Immunization. Molecular Therapy vol. 17, (9) 1643-1650.
10.1038/mt.2009.149
Rowe HM, Lopes L, Brown N, Efklidou S, Smallie T, Karrar S, Kaye PM, Collins MK(2009). Expression of vFLIP in a Lentiviral Vaccine Vector Activates NF-κB, Matures Dendritic Cells, and Increases CD8+ T-Cell Responses. Journal of Virology vol. 83, (4) 1555-1562.
10.1128/jvi.00709-08
Rowe HM, Lopes L, Ikeda Y, Bailey R, Barde I, Zenke M, Chain BM, Collins MK(2006). Immunization with a Lentiviral Vector Stimulates both CD4 and CD8 T Cell Responses to an Ovalbumin Transgene. Molecular Therapy vol. 13, (2) 310-319.
10.1016/j.ymthe.2005.08.025
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