Publications: Dr Helen Rowe
Enriquez-Gasca R, Gould PA, Tunbak H, Conde L, Herrero J, Chittka A, Beck CR, Gifford R et al.
(
2023
)
.
Co-option of endogenous retroviruses through genetic escape from TRIM28 repression
.
Cell Reports
vol.
42
,
(
6
)
Rowe H
(
2023
)
.
Shrouded in genomic heterochromatin are ancient viral-like elements that could jump
.
Open Access Government
vol.
37
,
(
1
)
182
-
183
.
Fernandes LP, Enriquez-Gasca R, Gould PA, Holt JH, Conde L, Ecco G, Herrero J, Gifford R et al.
(
2022
)
.
A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819
.
Science Advances
vol.
8
,
(
43
)
(
2022
)
.
Implications of the first complete human genome assembly
.
Genome Research
vol.
32
,
(
4
)
595
-
598
.
Rowe H
(
2022
)
.
Satellite DNA arrays barcode chromosomes to regulate genes
.
Open Access Government
vol.
36
,
(
1
)
138
-
139
.
Gale Hammell M, Rowe HM
(
2020
)
.
Editorial Overview: Endogenous Retroviruses in Development and Disease
.
Viruses
vol.
12
,
(
12
)
1446
-
1446
.
Tunbak H, Enriquez-Gasca R, Tie CHC, Gould PA, Mlcochova P, Gupta RK, Fernandes L, Holt J et al.
(
2020
)
.
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s
.
Nature Communications
vol.
11
,
(
1
)
Enriquez-Gasca R, Gould PA, Rowe HM
(
2020
)
.
Host Gene Regulation by Transposable Elements: The New, the Old and the Ugly
.
Viruses
vol.
12
,
(
10
)
Gould PA, Rowe HM
(
2019
)
.
A nuclear licence to silence transposons
.
EMBO reports
vol.
20
,
(
12
)
Tie CHC, Fernandes L, Conde L, Robbez‐Masson L, Sumner RP, Peacock T, Rodriguez‐Plata MT, Mickute G et al.
(
2018
)
.
KAP1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control
.
EMBO Reports
vol.
19
,
(
10
)
Robbez-Masson L, Tie CHC, Conde L, Tunbak H, Husovsky C, Tchasovnikarova IA, Timms RT, Herrero J et al.
(
2018
)
.
The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes
.
Genome Research
vol.
28
,
(
6
)
836
-
845
.
Smith-Moore S, Neil SJD, Fraefel C, Linden RM, Bollen M, Rowe HM, Henckaerts E
(
2018
)
.
Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome
.
Proceedings of the National Academy of Sciences
vol.
115
,
(
15
)
E3529
-
E3538
.
Robbez-Masson L, Tie CHC, Rowe HM
(
2017
)
.
Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!
.
Journal of Cell Biology
vol.
216
,
(
11
)
3429
-
3431
.
Tie CH, Rowe HM
(
2017
)
.
Epigenetic control of retrotransposons in adult tissues: implications for immune regulation
.
Current Opinion in Virology
vol.
25
,
28
-
33
.
Ecco G, Cassano M, Kauzlaric A, Duc J, Coluccio A, Offner S, Imbeault M, Rowe HM et al.
(
2016
)
.
Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues
.
Dev Cell
vol.
36
,
(
6
)
611
-
623
.
Ecco G, Rowe HM, Trono D
(
2016
)
.
A Large-Scale Functional Screen to Identify Epigenetic Repressors of Retrotransposon Expression
.
Transposons and Retrotransposons
,
vol.
1400
,
Springer Nature
Robbez-Masson L, Rowe HM
(
2015
)
.
Retrotransposons shape species-specific embryonic stem cell gene expression
.
Retrovirology
vol.
12
,
(
1
)
Friedli M, Turelli P, Kapopoulou A, Rauwel B, Castro-Díaz N, Rowe HM, Ecco G, Unzu C et al.
(
2014
)
.
Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency
.
Genome Research
vol.
24
,
(
8
)
1251
-
1259
.
Corsinotti A, Kapopoulou A, Gubelmann C, Imbeault M, de Sio FRS, Rowe HM, Mouscaz Y, Deplancke B et al.
(
2013
)
.
Global and Stage Specific Patterns of Krüppel-Associated-Box Zinc Finger Protein Gene Expression in Murine Early Embryonic Cells
.
PLOS ONE
vol.
8
,
(
2
)
Rowe HM, Friedli M, Offner S, Verp S, Mesnard D, Marquis J, Aktas T, Trono D
(
2013
)
.
De novo DNA methylation of endogenous retroviruses is shaped by KRAB-ZFPs/KAP1 and ESET
.
Development
vol.
140
,
(
3
)
519
-
529
.
Rowe HM, Kapopoulou A, Corsinotti A, Fasching L, Macfarlan TS, Tarabay Y, Viville S, Jakobsson J et al.
(
2012
)
.
TRIM28 repression of retrotransposon-based enhancers is necessary to preserve transcriptional dynamics in embryonic stem cells
.
Genome Research
vol.
23
,
(
3
)
452
-
461
.
Macfarlan TS, Gifford WD, Driscoll S, Lettieri K, Rowe HM, Bonanomi D, Firth A, Singer O et al.
(
2012
)
.
Embryonic stem cell potency fluctuates with endogenous retrovirus activity
.
Nature
vol.
487
,
(
7405
)
57
-
63
.
Rowe HM, Trono D
(
2011
)
.
Dynamic control of endogenous retroviruses during development
.
Virology
vol.
411
,
(
2
)
273
-
287
.
Rowe HM, Jakobsson J, Mesnard D, Rougemont J, Reynard S, Aktas T, Maillard PV, Layard-Liesching H et al.
(
2010
)
.
KAP1 controls endogenous retroviruses in embryonic stem cells
.
Nature
vol.
463
,
(
7278
)
237
-
240
.
Arce F, Rowe HM, Chain B, Lopes L, Collins MK
(
2009
)
.
Lentiviral vectors transduce proliferating dendritic cell precursors leading to persistent antigen presentation and immunization
.
Molecular Therapy
vol.
17
,
(
9
)
1643
-
1650
.
Rowe HM, Lopes L, Brown N, Efklidou S, Smallie T, Karrar S, Kaye PM, Collins MK
(
2009
)
.
Expression of vFLIP in a lentiviral vaccine vector activates NF-{kappa}B, matures dendritic cells, and increases CD8+ T-cell responses
.
Journal of Virology
vol.
83
,
(
4
)
1555
-
1562
.
Rowe HM, Lopes L, Ikeda Y, Bailey R, Barde I, Zenke M, Chain BM, Collins MK
(
2005
)
.
Immunization with a Lentiviral Vector Stimulates both CD4 and CD8 T Cell Responses to an Ovalbumin Transgene
.
Molecular Therapy
vol.
13
,
(
2
)
310
-
319
.