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Publications:  Dr Andrew Finch

Sirey TM, Roberts K, Haerty W, Bedoya-Reina O, Rogatti-Granados S, Tan JY, Li N, Heather LC et al.(2019). Erratum: Correction: The long non-coding RNA Cerox1 is a post transcriptional regulator of mitochondrial complex I catalytic activity (eLife (2019) 8 PII: e50980). eLife vol. 8,
10.7554/eLife.50980
Pantazi A, Quintanilla A, Hari P, Tarrats N, Parasyraki E, Dix FL, Patel J, Chandra T et al.(2019). Inhibition of the 60S ribosome biogenesis GTPase LSG1 causes endoplasmic reticular disruption and cellular senescence. Aging Cell vol. 18, (4)
10.1111/acel.12981
Hari P, Millar FR, Tarrats N, Birch J, Quintanilla A, Rink CJ, Fernández-Duran I, Muir M et al.(2019). The innate immune sensor Toll-like receptor 2 controls the senescence-associated secretory phenotype. Science Advances vol. 5, (6)
10.1126/sciadv.aaw0254
Sirey TM, Roberts K, Haerty W, Bedoya-Reina O, Granados SR, Tan JY, Li N, Heather LC et al.(2019). The long non-coding rna cerox1 is a post transcriptional regulator of mitochondrial complex i catalytic activity. eLife vol. 8,
10.7554/eLife.45051
Handley MT, Reddy K, Wills J, Rosser E, Kamath A, Halachev M, Falkous G, Williams D et al.(2019). ITPase deficiency causes a martsolf-like syndrome with a lethal infantile dilated cardiomyopathy. PLoS Genetics vol. 15, (3)
10.1371/journal.pgen.1007605
Guitart AV, Finch AJ, Kranc KR(2018). Ca<sup>2+</sup>tapulting HSCs into action. Journal of Experimental Medicine vol. 215, (8) 1971-1973.
10.1084/jem.20181097
https://qmro.qmul.ac.uk/xmlui/handle/123456789/65483
Wills J, Edwards-Hicks J, Finch AJ(2017). AssayR: A Simple Mass Spectrometry Software Tool for Targeted Metabolic and Stable Isotope Tracer Analyses. Analytical Chemistry vol. 89, (18) 9616-9619.
10.1021/acs.analchem.7b02401
Yeyati PL, Schiller R, Mali G, Kasioulis I, Kawamura A, Adams IR, Playfoot C, Gilbert N et al.(2017). KDM3A coordinates actin dynamics with intraflagellar transport to regulate cilia stability. Journal of Cell Biology vol. 216, (4) 999-1013.
10.1083/jcb.201607032
Guitart AV, Panagopoulou TI, Villacreces A, Vukovic M, Sepulveda C, Allen L, Carter RN, van de Lagemaat LN et al.(2017). Fumarate hydratase is a critical metabolic regulator of hematopoietic stem cell functions. The Journal of experimental medicine vol. 214, (3) 719-735.
10.1084/jem.20161087
https://qmro.qmul.ac.uk/xmlui/handle/123456789/59365
Meehan J, Ward C, Turnbull A, Bukowski-Wills J, Finch AJ, Jarman EJ, Xintaropoulou C, Martinez-Perez C et al.(2017). Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells. Oncotarget vol. 8, (26) 42857-42875.
10.18632/oncotarget.17143
Gammoh N, Fraser J, Puente C, Syred HM, Kang H, Ozawa T, Lam D, Acosta JC et al.(2016). Suppression of autophagy impedes glioblastoma development and induces senescence. Autophagy vol. 12, (9) 1431-1439.
10.1080/15548627.2016.1190053
Byrne KM, Monsefi N, Dawson JC, Degasperi A, Bukowski-Wills JC, Volinsky N, Dobrzy¿ski M, Birtwistle MR et al.(2016). Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches. Cell Systems vol. 2, (1) 38-48.
10.1016/j.cels.2016.01.003
Rainger J, Pehlivan D, Johansson S, Bengani H, Sanchez-Pulido L, Williamson KA, Ture M, Barker H et al.(2014). Monoallelic and biallelic mutations in MAB21L2 cause a spectrum of major eye malformations. American Journal of Human Genetics vol. 94, (6) 915-923.
10.1016/j.ajhg.2014.05.005
Kasioulis I, Syred HM, Tate P, Finch A, Shaw J, Seawright A, Fuszard M, Botting CH et al.(2014). Kdm3a lysine demethylase is an Hsp90 client required for cytoskeletal rearrangements during spermatogenesis. Molecular Biology of the Cell vol. 25, (8) 1216-1233.
10.1091/mbc.E13-08-0471
Hilcenko C, Simpson PJ, Finch AJ, Bowler FR, Churcher MJ, Jin L, Packman LC, Shlien A et al.(2013). Aberrant 3′ oligoadenylation of spliceosomal U6 small nuclear RNA in poikiloderma with neutropenia. Blood vol. 121, (6) 1028-1038.
10.1182/blood-2012-10-461491
Lutzny G, Kocher T, Schmidt-Supprian M, Rudelius M, Klein-Hitpass L, Finch AJ, Dürig J, Wagner M et al.(2013). Protein Kinase C-β-Dependent Activation of NF-κB in Stromal Cells Is Indispensable for the Survival of Chronic Lymphocytic Leukemia B Cells In Vivo. Cancer Cell vol. 23, (1) 77-92.
10.1016/j.ccr.2012.12.003
Finch AJ, Hilcenko C, Basse N, Drynan LF, Goyenechea B, Menne TF, Fernández AG, Simpson P et al.(2011). Uncoupling of GTP hydrolysis from eIF6 release on the ribosome causes shwachman-diamond syndrome. Genes and Development vol. 25, (9) 917-929.
10.1101/gad.623011
Finch AJ, Soucek L, Junttila MR, Swigart LB, Evan GI(2009). Acute overexpression of Myc in intestinal epithelium recapitulates some but not all the changes elicited by Wnt/β-catenin pathway activation. Molecular and Cellular Biology vol. 29, (19) 5306-5315.
10.1128/MCB.01745-08
Soucek L, Whitfield J, Martins CP, Finch AJ, Murphy DJ, Sodir NM, Karnezis AN, Swigart LB et al.(2008). Modelling Myc inhibition as a cancer therapy. Nature vol. 455, (7213) 679-683.
10.1038/nature07260
Cartlidge RA, Thomas GR, Cagnol S, Jong KA, Molton SA, Finch AJ, McMahon M(2008). Oncogenic BRAF<sup>V600E</sup> inhibits BIM expression to promote melanoma cell survival. Pigment Cell and Melanoma Research vol. 21, (5) 534-544.
10.1111/j.1755-148X.2008.00491.x
Ringshausen I, O'Shea CC, Finch AJ, Swigart LB, Evan GI(2006). Mdm2 is critically and continuously required to suppress lethal p53 activity in vivo. Cancer Cell vol. 10, (6) 501-514.
10.1016/j.ccr.2006.10.010
Christophorou MA, Ringshausen I, Finch AJ, Swigart LB, Evan GI(2006). The pathological response to DNA damage does not contribute to p53-mediated tumour suppression. Nature vol. 443, (7108) 214-217.
10.1038/nature05077
Finch A, Prescott J, Shchors K, Hunt A, Soucek L, Dansen TB, Swigart L, Evan GI(2006). Bcl-x<inf>L</inf> gain of function and p19<sup>ARF</sup> loss of function cooperate oncogenically with Myc in vivo by distinct mechanisms. Cancer Cell vol. 10, (2) 113-120.
10.1016/j.ccr.2006.06.017
Evan GI, Christophorou M, Lawlor EA, Ringshausen I, Prescott J, Dansen T, Finch A, Martins C et al. (2005). Oncogene-dependent tumor suppression: Using the dark side of the force for cancer therapy. Cold Spring Harbor Symposia on Quantitative Biology. vol. 70, 263-273.
10.1101/sqb.2005.70.054
Broaddus VC, Dansen TB, Abayasiriwardana KS, Wilson SM, Finch AJ, Swigart LB, Hunt AE, Evan GI(2005). Bid mediates apoptotic synergy between tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and DNA damage. Journal of Biological Chemistry vol. 280, (13) 12486-12493.
10.1074/jbc.M408190200
Finch A, Davis W, Carter WG, Saklatvala J(2001). Analysis of mitogen-activated protein kinase pathways used by interleukin 1 in tissues in vivo: Activation of hepatic c-Jun N-terminal kinases 1 and 2, and mitogen-activated protein kinase kinases 4 and 7. Biochemical Journal vol. 353, (2) 275-281.
10.1042/0264-6021:3530275
Meier P, Finch A, Evan G(2000). Apoptosis in development. Nature vol. 407, (6805) 796-801.
10.1038/35037734
Lasa M, Mahtani KR, Finch A, Brewer G, Saklatvala J, Clark AR(2000). Regulation of cyclooxygenase 2 mRNA stability by the mitogen- activated protein kinase p38 signaling cascade. Molecular and Cellular Biology vol. 20, (12) 4265-4274.
10.1128/MCB.20.12.4265-4274.2000
Saklatvala J, Dean J, Finch A(1999). Protein kinase cascades in intracellular signalling by interleukin-I and tumour necrosis factor. Biochemical Society Symposium vol. 64, 63-77.
Finch A, Holland P, Cooper J, Saklatvala J, Kracht M(1997). Selective activation of JNK/SAPK by interleukin-1 in rabbit liver is mediated by MKK7. FEBS Letters vol. 418, (1-2) 144-148.
10.1016/S0014-5793(97)01364-1
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