Menu
 
Research menu
Jump to menu

Publications:  Dr Roberto Bellelli

Bellelli R, Youds J, Borel V, Svendsen J, Pavicic-Kaltenbrunner V, Boulton SJ(2020). Synthetic Lethality between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication. Cell Reports vol. 31, (8)
10.1016/j.celrep.2020.107675
Logan CV, Murray JE, Parry DA, Robertson A, Bellelli R, Tarnauskait¿ Ž, Challis R, Cleal L et al.(2018). DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency. American Journal of Human Genetics vol. 103, (6) 1038-1044.
10.1016/j.ajhg.2018.10.024
Bellelli R, Belan O, Pye VE, Clement C, Maslen SL, Skehel JM, Cherepanov P, Almouzni G et al.(2018). POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication. Molecular Cell vol. 72, (1) 112-126.e5.
10.1016/j.molcel.2018.08.043
Bellelli R, Borel V, Logan C, Svendsen J, Cox DE, Nye E, Metcalfe K, O'Connell SM et al.(2018). Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis. Molecular Cell vol. 70, (4) 707-721.e7.
10.1016/j.molcel.2018.04.008
Margalef P, Kotsantis P, Borel V, Bellelli R, Panier S, Boulton SJ(2018). Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe. Cell vol. 172, (3) 439-453.e14.
10.1016/j.cell.2017.11.047
Bellelli R, Vitagliano D, Federico G, Marotta P, Tamburrino A, Salerno P, Paciello O, Papparella S et al.(2018). Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia. Molecular and Cellular Endocrinology vol. 460, 24-35.
10.1016/j.mce.2017.06.023
Federico G, Bellelli R, Nai A, Silvestri L, Camaschella C, Iolascon A, Santoro M, Carlomagno F (2017). NCOA4 Links Iron Bioavailability to DNA Metabolism. BLOOD. vol. 130,
Stingele J, Bellelli R, Boulton SJ(2017). Mechanisms of DNA-protein crosslink repair. Nature Reviews Molecular Cell Biology vol. 18, (9) 563-573.
10.1038/nrm.2017.56
Stingele J, Bellelli R, Alte F, Hewitt G, Sarek G, Maslen SL, Tsutakawa SE, Borg A et al.(2016). Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN. Molecular Cell vol. 64, (4) 688-703.
10.1016/j.molcel.2016.09.031
Bellelli R, Federico G, Matte' A, Colecchia D, Iolascon A, Chiariello M, Santoro M, De Franceschi L et al.(2016). NCOA4 Deficiency Impairs Systemic Iron Homeostasis. Cell Reports vol. 14, (3) 411-421.
10.1016/j.celrep.2015.12.065
Castellone MD, Laukkanen MO, Teramoto H, Bellelli R, Alì G, Fontanini G, Santoro M, Gutkind JS(2015). Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma. Oncogene vol. 34, (13) 1679-1687.
10.1038/onc.2014.104
Castellone MD, Langella A, Cantara S, Laurila JP, Laatikainen LE, Bellelli R, Pacini F, Salvatore M et al.(2014). Extracellular superoxide dismutase induces mouse embryonic fibroblast proliferative burst, growth arrest, immortalization, and consequent in vivo tumorigenesis. Antioxidants and Redox Signaling vol. 21, (10) 1460-1474.
10.1089/ars.2013.5475
Bellelli R, Castellone MD, Guida T, Limongello R, Dathan NA, Merolla F, Cirafici AM, Affuso A et al.(2014). NCOA4 transcriptional coactivator inhibits activation of DNA replication origins. Molecular Cell vol. 55, (1) 123-137.
10.1016/j.molcel.2014.04.031
Bellelli R, Castellone MD, Garcia-Rostan G, Ugolini C, Nucera C, Sadow PM, Nappi TC, Salerno P et al.(2012). FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma. Endocrine-Related Cancer vol. 19, (5) 695-710.
10.1530/ERC-12-0031
Faraonio R, Salerno P, Passaro F, Sedia C, Iaccio A, Bellelli R, Nappi TC, Comegna M et al.(2012). A set of miRNAs participates in the cellular senescence program in human diploid fibroblasts. Cell Death and Differentiation vol. 19, (4) 713-721.
10.1038/cdd.2011.143
Castellone MD, De Falco V, Rao DM, Bellelli R, Muthu M, Basolo F, Fusco A, Gutkind JS et al.(2009). The β-Catenin axis integrates multiple signals downstream from RET/Papillary thyroid carcinoma leading to cell proliferation. Cancer Research vol. 69, (5) 1867-1876.
10.1158/0008-5472.CAN-08-1982
Return to top