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Publications:  Dr Roberto Bellelli

Bellelli R, Youds J, Borel V, Svendsen J, Pavicic-Kaltenbrunner V, Boulton SJ(2020). Synthetic Lethality between DNA Polymerase Epsilon and RTEL1 in Metazoan DNA Replication. Cell Reports vol. 31, (8)
Bellelli R, Boulton SJ(2020). Spotlight on the Replisome: Aetiology of DNA Replication-Associated Genetic Diseases. Trends in Genetics
Logan CV, Murray JE, Parry DA, Robertson A, Bellelli R, Tarnauskait¿ Ž, Challis R, Cleal L et al.(2018). DNA Polymerase Epsilon Deficiency Causes IMAGe Syndrome with Variable Immunodeficiency. American Journal of Human Genetics vol. 103, (6) 1038-1044.
Bellelli R, Belan O, Pye VE, Clement C, Maslen SL, Skehel JM, Cherepanov P, Almouzni G et al.(2018). POLE3-POLE4 Is a Histone H3-H4 Chaperone that Maintains Chromatin Integrity during DNA Replication. Molecular Cell vol. 72, (1) 112-126.e5.
Bellelli R, Borel V, Logan C, Svendsen J, Cox DE, Nye E, Metcalfe K, O'Connell SM et al.(2018). Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis. Molecular Cell vol. 70, (4) 707-721.e7.
Margalef P, Kotsantis P, Borel V, Bellelli R, Panier S, Boulton SJ(2018). Stabilization of Reversed Replication Forks by Telomerase Drives Telomere Catastrophe. Cell vol. 172, (3) 439-453.e14.
Bellelli R, Vitagliano D, Federico G, Marotta P, Tamburrino A, Salerno P, Paciello O, Papparella S et al.(2018). Oncogene-induced senescence and its evasion in a mouse model of thyroid neoplasia. Molecular and Cellular Endocrinology vol. 460, 24-35.
Federico G, Bellelli R, Nai A, Silvestri L, Camaschella C, Iolascon A, Santoro M, Carlomagno F (2017). NCOA4 Links Iron Bioavailability to DNA Metabolism. BLOOD. vol. 130,
Stingele J, Bellelli R, Boulton SJ(2017). Mechanisms of DNA-protein crosslink repair. Nature Reviews Molecular Cell Biology vol. 18, (9) 563-573.
Stingele J, Bellelli R, Alte F, Hewitt G, Sarek G, Maslen SL, Tsutakawa SE, Borg A et al.(2016). Mechanism and Regulation of DNA-Protein Crosslink Repair by the DNA-Dependent Metalloprotease SPRTN. Molecular Cell vol. 64, (4) 688-703.
Bellelli R, Federico G, Matte' A, Colecchia D, Iolascon A, Chiariello M, Santoro M, De Franceschi L et al.(2016). NCOA4 Deficiency Impairs Systemic Iron Homeostasis. Cell Reports vol. 14, (3) 411-421.
Castellone MD, Laukkanen MO, Teramoto H, Bellelli R, Alì G, Fontanini G, Santoro M, Gutkind JS(2015). Cross talk between the bombesin neuropeptide receptor and Sonic hedgehog pathways in small cell lung carcinoma. Oncogene vol. 34, (13) 1679-1687.
Castellone MD, Langella A, Cantara S, Laurila JP, Laatikainen LE, Bellelli R, Pacini F, Salvatore M et al.(2014). Extracellular superoxide dismutase induces mouse embryonic fibroblast proliferative burst, growth arrest, immortalization, and consequent in vivo tumorigenesis. Antioxidants and Redox Signaling vol. 21, (10) 1460-1474.
Bellelli R, Castellone MD, Guida T, Limongello R, Dathan NA, Merolla F, Cirafici AM, Affuso A et al.(2014). NCOA4 transcriptional coactivator inhibits activation of DNA replication origins. Molecular Cell vol. 55, (1) 123-137.
Bellelli R, Castellone MD, Garcia-Rostan G, Ugolini C, Nucera C, Sadow PM, Nappi TC, Salerno P et al.(2012). FOXM1 is a molecular determinant of the mitogenic and invasive phenotype of anaplastic thyroid carcinoma. Endocrine-Related Cancer vol. 19, (5) 695-710.
Faraonio R, Salerno P, Passaro F, Sedia C, Iaccio A, Bellelli R, Nappi TC, Comegna M et al.(2012). A set of miRNAs participates in the cellular senescence program in human diploid fibroblasts. Cell Death and Differentiation vol. 19, (4) 713-721.
Castellone MD, De Falco V, Rao DM, Bellelli R, Muthu M, Basolo F, Fusco A, Gutkind JS et al.(2009). The β-Catenin axis integrates multiple signals downstream from RET/Papillary thyroid carcinoma leading to cell proliferation. Cancer Research vol. 69, (5) 1867-1876.
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