Publications: Dr Diu Nguyen

Wakiro I, Huang Y, Yang X, Xie X, Luo H, Chang K, Pierson A, Batchelor E et al. ( 2024 ) . Rbmx Regulates YTHDC1 Nuclear Condensates to Promote Nascent Transcription in Acute Myeloid Leukemia . Blood vol. 144 , ( Supplement 1 ) 627 - 627 .

Xie X, Chavez FH, Baali I, Chu EL, Evans C, Yang X, Wei W, Luo H et al. ( 2024 ) . Uncovering the HOXA9 Translational Regulatory Complex That Promotes AML Leukemic Stem Cells . Blood vol. 144 , ( Supplement 1 ) 4106 - 4106 .

Herrejon Chavez F, Luo H, Cifani P, Pine A, Chu EL, Joshi S, Barin E, Schurer A et al. ( 2023 ) . RNA binding protein SYNCRIP maintains proteostasis and self-renewal of hematopoietic stem and progenitor cells . Nature Communications vol. 14 , ( 1 )

Mlynarczyk C, Teater M, Pae J, Chin CR, Wang L, Arulraj T, Barisic D, Papin A et al. ( 2023 ) . BTG1 mutation yields supercompetitive B cells primed for malignant transformation . Science vol. 379 , ( 6629 )

Prieto C, Nguyen DTT, Liu Z, Wheat J, Perez A, Gourkanti S, Chou T, Barin E et al. ( 2021 ) . Transcriptional control of CBX5 by the RNA-binding proteins RBMX and RBMXL1 maintains chromatin state in myeloid leukemia . Nature Cancer vol. 2 , ( 7 ) 741 - 757 .

Cheng Y, Xie W, Pickering BF, Chu KL, Savino AM, Yang X, Luo H, Nguyen DT et al. ( 2021 ) . N6-Methyladenosine on mRNA facilitates a phase-separated nuclear body that suppresses myeloid leukemic differentiation . Cancer Cell vol. 39 , ( 7 ) 958 - 972.e8 .

Nguyen DTT, Lu Y, Chu EL, Yang X, Park S-M, Choo Z-N, Chin CR, Prieto C et al. ( 2020 ) . HyperTRIBE uncovers increased MUSASHI-2 RNA binding activity and differential regulation in leukemic stem cells . Nature Communications vol. 11 , ( 1 )

Cheng Y, Luo H, Izzo F, Pickering BF, Nguyen D, Myers R, Schurer A, Gourkanti S et al. ( 2019 ) . m6A RNA Methylation Maintains Hematopoietic Stem Cell Identity and Symmetric Commitment . Cell Reports vol. 28 , ( 7 ) 1703 - 1716.e6 .

Vu LP, Pickering BF, Cheng Y, Zaccara S, Nguyen D, Minuesa G, Chou T, Chow A et al. ( 2017 ) . The N6-methyladenosine (m6A)-forming enzyme METTL3 controls myeloid differentiation of normal hematopoietic and leukemia cells . Nature Medicine vol. 23 , ( 11 ) 1369 - 1376 .

Nguyen DT, Voon HPJ, Xella B, Scott C, Clynes D, Babbs C, Ayyub H, Kerry J et al. ( 2017 ) . The chromatin remodelling factor ATRX suppresses R‐loops in transcribed telomeric repeats . EMBO Reports vol. 18 , ( 6 ) 914 - 928 .

Bousquet M, Nguyen D, Chen C, Shields L, Lodish HF ( 2012 ) . MicroRNA-125b transforms myeloid cell lines by repressing multiple mRNA . Haematologica vol. 97 , ( 11 ) 1713 - 1721 .