Publications: Prof Jude Fitzgibbon

Lin WY, Fordham SE, Hungate E, Sunter NJ, Elstob C, Xu Y, Park C, Quante A et al. ( 2022 ) . Author Correction: Genome-wide association study identifies susceptibility loci for acute myeloid leukemia (Nature Communications, (2021), 12, 1, (6233), 10.1038/s41467-021-26551-x) . Nature Communications vol. 13 , ( 1 )

Hug N, Aitken S, Longman D, Raab M, Armes H, Mann AR, Rio-Machin A, Fitzgibbon J et al. ( 2022 ) . A dual role for the RNA helicase DHX34 in NMD and pre-mRNA splicing and its function in hematopoietic differentiation . RNA vol. 28 , ( 9 ) 1224 - 1238 .

Rio‐Machin A, Fitzgibbon J ( 2022 ) . DDX41: the poster child for familial AML . Blood vol. 140 , ( 7 ) 667 - 669 .

Grey W, Rio-Machin A, Casado P, Grönroos E, Ali S, Miettinen JJ, Bewicke-Copley F, Parsons A et al. ( 2022 ) . CKS1 inhibition depletes leukemic stem cells and protects healthy hematopoietic stem cells in acute myeloid leukemia . Science Translational Medicine vol. 14 , ( 650 )

Armes H, Rio-Machin A, Krizsán S, Bödör C, Kaya F, Bewicke-Copley F, Alnajar J, Walne A et al. ( 2022 ) . Acquired somatic variants in inherited myeloid malignancies . Leukemia vol. 36 , ( 5 ) 1377 - 1381 .

Armes H, Bewicke-Copley F, Rio-Machin A, Di Bella D, Philippe C, Wozniak A, Tummala H, Wang J et al. ( 2022 ) . Germline ERCC excision repair 6 like 2 (ERCC6L2) mutations lead to impaired erythropoiesis and reshaping of the bone marrow microenvironment . British Journal of Haematology

Gerdes H, Casado P, Dokal A, Hijazi M, Akhtar N, Osuntola R, Rajeeve V, Fitzgibbon J et al. ( 2021 ) . Drug ranking using machine learning systematically predicts the efficacy of anti-cancer drugs . Nature Communications vol. 12 , ( 1 )

Lin WY, Fordham SE, Hungate E, Sunter NJ, Elstob C, Xu Y, Park C, Quante A et al. ( 2021 ) . Genome-wide association study identifies susceptibility loci for acute myeloid leukemia . Nature Communications vol. 12 , ( 1 )

Homan CC, King-Smith SL, Lawrence DM, Arts P, Feng J, Andrews J, Armstrong M, Ha T et al. ( 2021 ) . The RUNX1 database (RUNX1db): Establishment of an expert curated RUNX1 registry and genomics database as a public resource for familial platelet disorder with myeloid malignancy . Haematologica vol. 106 , ( 11 ) 3004 - 3007 .

Heward J, Konali L, D'Avola A, Close K, Yeomans A, Philpott M, Dunford J, Rahim T et al. ( 2021 ) . KDM5 inhibition offers a novel therapeutic strategy for the treatment of KMT2D mutant lymphomas . Blood vol. 138 , ( 5 ) 370 - 381 .

Rio-Machin A, Fitzgibbon J ( 2021 ) . Germline ETV6 variants: not ALL created equally . Blood vol. 137 , ( 3 ) 288 - 289 .

Maybury BD, Saavedra-Torres Y, Snoeks TJA, Fitzgibbon J, Calado DP ( 2021 ) . Generation and Surgical Analysis of Genetic Mouse Models to Study NF-κB-Driven Pathogenesis of Diffuse Large B Cell Lymphoma . vol. 2366 , 321 - 342 .

Fitzgibbon J, Weigert O ( 2021 ) . Molecular genetics in indolent lymphomas . Hematologic Malignancies ,

Fitzgibbon J ( 2020 ) . Inherited Myeloid Malignancies . EUROPEAN JOURNAL OF HUMAN GENETICS . vol. 28 , 17 - 17 .

Rio-Machin A, Vulliamy T, Hug N, Walne A, Tawana K, Cardoso S, Ellison A, Pontikos N et al. ( 2020 ) . The complex genetic landscape of familial MDS and AML reveals pathogenic germline variants . Nature Communications vol. 11 , ( 1 )

Rio-Machin A, Casado-Izquierdo P, Miettinen J, Bewicke-Copley F, Khan N, Demeulemeester J, Krizsán S, Zheng J et al. ( 2020 ) . Integration of Deep Multi-Omics Profiling Veals New Insights into the Biology of Poor-Risk Acute Myeloid Leukemia . Blood vol. 136 , ( Supplement 1 ) 39 - 40 .

Uyulur F, Bewicke-Copley F, Anene CA, Schlesner M, MMML-Seq Project I, Siebert R, Okosun J, Fitzgibbon J et al. ( 2020 ) . Systematic Evaluation of Somatic Cis -Regulatory Mutations in Follicular Lymphoma . Blood vol. 136 , ( Supplement 1 ) 26 - 27 .

Larrea E, Fernandez‐mercado M, Guerra‐assunção JA, Wang J, Goicoechea I, Gaafar A, Ceberio I, Lobo C et al. ( 2020 ) . Identification of recurrent mutations in the microrna‐binding sites of b‐cell lymphoma‐ associated genes in follicular lymphoma . International Journal of Molecular Sciences vol. 21 , ( 22 ) 1 - 12 .

Kumar EA, Okosun J, Fitzgibbon J ( 2020 ) . The Biological Basis of Histologic Transformation . Hematology/Oncology Clinics of North America vol. 34 , ( 4 ) 771 - 784 .

Dokal I, Tummala H, Vulliamy T, Walne A ( 2020 ) . A frameshift variant in the specificity protein 1 triggers superactivation of SP1-mediated transcription in familial bone marrow failure . Proceedings of the National Academy of Sciences of USA Article 32636268 ,

Fitzgibbon J, Park S, Cook G, Paiva B, Gloghini A, Van Breda E, Busti F, Garderet L et al. ( 2020 ) . Recent Advancements in Hematology: Knowledge, Methods and Dissemination, Part 1 . Hemato vol. 1 , ( 1 )

Araf S, Korfi K, Bewicke-Copley F, Wang J, Cogliatti S, Kumar E, Forrer F, Barrington SF et al. ( 2020 ) . Genetic heterogeneity highlighted by differential FDG-PET response in diffuse large B-cell lymphoma . Haematologica vol. 105 , ( 6 ) E318 - E321 .

Waclawiczek A, Hamilton A, Rouault-Pierre K, Abarrategi A, Albornoz MG, Miraki-Moud F, Bah N, Gribben J et al. ( 2020 ) . Mesenchymal niche remodeling impairs hematopoiesis via stanniocalcin 1 in acute myeloid leukemia . Journal of Clinical Investigation vol. 130 , ( 6 ) 3038 - 3050 .

Cucco F, Barrans S, Sha C, Clipson A, Crouch S, Dobson R, Chen Z, Thompson JS et al. ( 2020 ) . Distinct genetic changes reveal evolutionary history and heterogeneous molecular grade of DLBCL with MYC/BCL2 double-hit . Leukemia vol. 34 , ( 5 ) 1329 - 1341 .

Maybury B, Fitzgibbon J, Calado D ( 2020 ) . An immunocompetent, spontaneous mouse model of DLBCL for studying the response to R-CHOP and identifying new treatment targets . BRITISH JOURNAL OF HAEMATOLOGY . vol. 189 , 110 - 111 .

Fitzgibbon J, Busca A, Gloghini A, López-Guillermo A, Orazi A, Carlo-Stella C, Andrès E, Van Breda E et al. ( 2020 ) . Recent Advancements in Hematology: Knowledge, Methods and Dissemination . Hemato vol. 1 , ( 1 ) 5 - 6 .

Charrot S, Armes H, Rio-Machin A, Fitzgibbon J ( 2020 ) . AML through the prism of molecular genetics . British Journal of Haematology vol. 188 , ( 1 ) 49 - 62 .

Carbone A, Roulland S, Gloghini A, Younes A, von Keudell G, López-Guillermo A, Fitzgibbon J ( 2019 ) . Follicular lymphoma . Nature Reviews Disease Primers vol. 5 , ( 1 )

Jurinovic V, Passerini V, Oestergaard MZ, Knapp A, Mundt K, Araf S, Richter J, Fitzgibbon J et al. ( 2019 ) . Evaluation of the m7-FLIPI in Patients with Follicular Lymphoma Treated within the Gallium Trial: EZH2 mutation Status May be a Predictive Marker for Differential Efficacy of Chemotherapy . Blood . vol. 134 , 122 - 122 .

Bewicke-Copley F, Korfi K, Araf S, Kumar EA, Cummin TEC, Ashton-Key M, Barrans S, Van Hoppe S et al. ( 2019 ) . Longitudinal Analyses of Diagnostic-Relapse Biopsies of Diffuse Large B Cell Lymphoma Reveal a Poor Risk Subset of ABC Patients Based on the Expression of a 30 Gene Panel . Blood vol. 134 , ( Supplement_1 ) 2769 - 2769 .

Ortega-Molina A, Deleyto-Seldas N, Carreras J, Sanz A, Lebrero-Fernández C, Menéndez C, Vandenberg A, Fernández-Ruiz B et al. ( 2019 ) . Oncogenic Rag GTPase signalling enhances B cell activation and drives follicular lymphoma sensitive to pharmacological inhibition of mTOR . Nature Metabolism vol. 1 , ( 8 ) 775 - 789 .

Okosun J, Bödör C, Batlevi C, Nagy N, Michot J, Schneider T, Alizadeh H, Simon Z et al. ( 2019 ) . EZH2 GAIN‐OF‐FUNCTION MUTATIONS ARE NOT ASSOCIATED WITH MORE FAVORABLE PROGNOSIS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA (FL): A PRELIMINARY ANALYSIS ON 590 PATIENTS . Hematological Oncology vol. 37 , 192 - 193 .

Korfi K, Araf S, Bewicke‐Copley F, Kumar E, Cummin T, Ashton‐Key M, Barrans S, Van Hoppe S et al. ( 2019 ) . LONGITUDINAL ANALYSES OF DIAGNOSTIC‐RELAPSE BIOPSIES OF DIFFUSE LARGE B CELL LYMPHOMA SUGGEST THAT RELAPSE IS MEDIATED BY DISTINCT MECHANISMS IN ABC AND GCB LYMPHOMA . Hematological Oncology vol. 37 , 142 - 143 .

Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al. ( 2019 ) . Correction: Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma (Leukemia, (2018), 32, 5, (1261-1265), 10.1038/s41375-018-0043-y) . Leukemia vol. 33 , ( 6 )

Kumar E, Korfi K, Bewicke-Copley F, Witzig T, Leukam M, Ansell S, Scott J, Rallis K et al. ( 2019 ) . MUTATIONS AFFECTING THE CREBBP HAT DOMAIN PREDICT RESPONSE TO MTOR INHIBITORS EVEROLIMUS AND TEMSIROLIMUS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA . HemaSphere vol. 3 ,

Rio-Machin A, Vulliamy T, Hug N, Caceres JF, Fitzgibbon J, Dokal I ( 2019 ) . PF213 THE GENETIC LANDSCAPE OF FAMILIAL MDS/AML; RECURRING MUTATIONS IN THE RNA HELICASE DHX34 LEADING TO DEFECTS IN NONSENSE-MEDIATED RNA DECAY . HemaSphere vol. 3 , ( S1 )

Kumar E, Korfi K, Bewicke-Copley F, Witzig T, Leukam M, Ansell S, Scott J, Rallis K et al. ( 2019 ) . PF513 MUTATIONS AFFECTING THE CREBBP HAT DOMAIN PREDICT RESPONSE TO MTOR INHIBITORS EVEROLIMUS AND TEMSIROLIMUS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA . HemaSphere vol. 3 , ( S1 )

Bödör C, Batlevi C, Nagy N, Michot J-M, Schneider T, Alizadeh H, Simon Z, Vose J et al. ( 2019 ) . PS1247 EZH2 GAIN-OF-FUNCTION MUTATIONS ARE NOT ASSOCIATED WITH MORE FAVORABLE PROGNOSIS IN RELAPSED/REFRACTORY FOLLICULAR LYMPHOMA: A PRELIMINARY ANALYSIS ON 590 PATIENTS . HemaSphere vol. 3 , ( S1 ) 568 - 569 .

Heward J, Koniali L, D’Avola A, Close K, Yeomans A, Johnson P, Okosun J, Neve R et al. ( 2019 ) . S844 KDM5 INHIBITION OFFERS A NOVEL THERAPEUTIC STRATEGY FOR THE TREATMENT OF KMT2D MUTANT LYMPHOMAS . HemaSphere vol. 3 , ( S1 ) 376 - 377 .

Araf S, Wang J, Ashton-Key M, Korfi K, Di Bella D, Rio-Machin A, Odabashian M, Foria V et al. ( 2019 ) . Transmission of diffuse large B-cell lymphoma by an allogeneic stem-cell transplant . Haematologica vol. 104 , ( 4 ) e174 - e177 .

Merron B, Kazmi-Stokes S, Cummin T, Barrans S, Araf S, Korfi K, Pascua LDL, Caddy J et al. ( 2019 ) . Precision medicine for patients with lymphoma; the Bloodwise Precision Medicine for Aggressive Lymphomas (PMAL) consortium . Clinical Medicine vol. 19 , ( Suppl 2 ) 100 - 101 .

Jakobsen JS, Laursen LG, Schuster MB, Pundhir S, Schoof E, Ge Y, D'Altri T, Vitting-Seerup K et al. ( 2019 ) . Mutant CEBPA directly drives the expression of the targetable tumor-promoting factor CD73 in AML . Science Advances vol. 5 , ( 7 )

Brown AL, Armstrong M, Lawrence D, Wang P, Arts P, Duployez N, Churpek J, Tawana K et al. ( 2018 ) . Development of a Data Portal for Aggregation and Analysis of Genomics Data in Familial Platelet Disorder with Predisposition to Myeloid Malignancy - the RUNX1.DB . Blood vol. 132 , ( Supplement 1 ) 5241 - 5241 .

DOKAL I, TUMMALA H, VULLIAMY T ( 2018 ) . homozygous OB-fold variants in telomere protein TPP1 are associated with dyskeratosis congenita-like phenotypes . Blood vol. 132 , 1349 - 1353 .

Casado P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Iqbal S et al. ( 2018 ) . Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells . Leukemia vol. 32 , ( 8 ) 1818 - 1822 .

Okosun J, Kridel R, Fitzgibbon J ( 2018 ) . Rituximab as a first step in tackling transformation . The Lancet Haematology vol. 5 , ( 8 ) e326 - e327 .

Heward JA, Kumar EA, Korfi K, Okosun J, Fitzgibbon J ( 2018 ) . Precision medicine and lymphoma . Curr Opin Hematol vol. 25 , ( 4 ) 329 - 334 .

Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward J et al. ( 2018 ) . Genomic profiling reveals spatial intra-tumor heterogeneity in follicular lymphoma . Leukemia vol. 32 , ( 5 ) 1258 - 1263 .

Al Seraihi AF, Rio-Machin A, Tawana K, Bödör C, Wang J, Nagano A, Heward JA, Iqbal S et al. ( 2018 ) . GATA2 monoallelic expression underlies reduced penetrance in inherited GATA2-mutated MDS/AML . Leukemia vol. 32 , ( 11 ) 2502 - 2507 .

Araf S, Okosun J, Fitzgibbon J ( 2018 ) . Predicting early relapse in follicular lymphoma: have we turned a corner? . The Lancet Oncology vol. 19 , ( 4 ) 441 - 442 .

Casado P, Wilkes EH, Miraki-Moud F, Hadi MM, Rio-Machin A, Rajeeve V, Pike R, Iqbal S et al. ( 2017 ) . Proteomic and genomic integration identifies kinase and differentiation determinants of kinase inhibitor sensitivity in leukemia cells . Leukemia

Araf S, Wang J, Korfi K, Pangault C, Kotsiou E, Rio-Machin A, Rahim T, Heward JA et al. ( 2017 ) . Genomic Profiling Reveals Spatial Intra-Tumor Heterogeneity in Follicular Lymphoma . BLOOD . vol. 130 ,

Araf S, Korfi K, Nagano A, Cummin TEC, Bentley M, Thorner AR, Ashton-Key M, Calaminici M et al. ( 2017 ) . Longitudinal Analyses of the Genomic, Transcriptomic, and T Cell Repertoire in Diffuse Large B Cell Lymphoma Demonstrates Changes in Signaling and Immune Recognition at Relapse . BLOOD . vol. 130 ,

Gascoyne RD, Nadel B, Pasqualucci L, Fitzgibbon J, Payton JE, Melnick A, Weigert O, Tarte K et al. ( 2017 ) . Follicular lymphoma: State-of-the-art ICML workshop in Lugano 2015 . Hematological Oncology vol. 35 , ( 4 ) 397 - 407 .

Horton SJ, Giotopoulos G, Yun H, Vohra S, Sheppard O, Bashford-Rogers R, Rashid M, Clipson A et al. ( 2017 ) . Early loss of Crebbp confers malignant stem cell properties on lymphoid progenitors . Nature Cell Biology . vol. 19 , 1093 - 1104 .

Rio-Machin A, Gómez-López G, Muñoz J, Garcia-Martinez F, Maiques-Diaz A, Alvarez S, Salgado RN, Shrestha M et al. ( 2017 ) . The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia . Leukemia vol. 31 , ( 9 ) 2000 - 2005 .

Tawana K, Wang J, Király PA, Kállay K, Benyó G, Zombori M, Csomor J, Al Seraihi A et al. ( 2017 ) . Recurrent somatic JAK-STAT pathway variants within a RUNX1-mutated pedigree . European Journal of Human Genetics vol. 25 , ( 8 ) 1020 - 1024 .

Cummin TE, Araf S, Du M, Barrans S, Bentley MA, Clipson A, Wang M, Ahmed S et al. ( 2017 ) . PROGNOSTIC SIGNIFICANCE AND CORRELATION TO GENE EXPRESSION PROFILE OF EZH2 MUTATIONS IN DIFFUSE LARGE B‐CELL LYMPHOMA (DLBL) IN 2 LARGE PROSPECTIVE STUDIES . Hematological Oncology vol. 35 , ( S2 ) 158 - 159 .

Tawana K, Rio-Machin A, Preudhomme C, Fitzgibbon J ( 2017 ) . Familial CEBPA-mutated acute myeloid leukemia . Seminars in Hematology vol. 54 , ( 2 ) 87 - 93 .

Korfi K, Ali S, Heward JA, Fitzgibbon J ( 2017 ) . Follicular lymphoma, a B cell malignancy addicted to epigenetic mutations . Epigenetics vol. 12 , ( 5 ) 370 - 377 .

Casado P, Wilkes E, Hadi MM, Rajeeve V, Miraki-Moud F, Pike R, Del Rio-Machin A, Iqbal S et al. ( 2016 ) . Differentiation Status Revealed By Shotgun Phosphoproteomics Determines Sensitivity of Primary AML Cells to Kinase Inhibitors . Blood . vol. 128 , 840 - 840 .

Fitzgibbon J ( 2016 ) . Genomic Discovery, Prognosis, and Target Therapy Development . Blood vol. 128 , ( 22 )

Rio-Machin A, Gomez-Lopez G, Maiques-Diaz A, Alvarez S, Calasanz MJ, Fitzgibbon J, Cigudosa JC ( 2016 ) . HDAC Inhibitors As Novel Targeted Therapies for NUP98-HOXA9 AML Patients . Blood . vol. 128 , 2685 - 2685 .

Noerenberg D, Mansouri L, Young E, Mareike F, Abdulla M, Asmar F, Gonzalez-Farre B, Anna T et al. ( 2016 ) . NFKBIE Deletions: A Novel Marker of Clinical Aggressiveness in Primary Mediastinal B-Cell Lymphoma . BLOOD . vol. 128 ,

Britton DJ, Wilkes E, Casado P, Rajeeve V, Fitzgibbon J, Gribben J, Cutillas PR ( 2016 ) . Proteomic Analysis Directs Effective Drug Selection in Relapsed AML By Quantifying Drug Targets . Blood . vol. 128 , 5265 - 5265 .

Al Seraihi A, Rio-Machin A, Tawana K, Bödör C, Araf S, Heward JA, Smith M, Iqbal S et al. ( 2016 ) . Variable Penetrance Is Linked with Monoallelic Gene Expression in Inherited GATA2-Mutated MDS/AML . Blood . vol. 128 , 3916 - 3916 .

Noerenberg* D, Mansouri* L, Young E, Mareike F, Abdulla M, Asmar F, Gonzalez-Farre B, Anna T et al. ( 2016 ) . ΝFΚΒΙΕ Deletions: A Novel Marker of Clinical Aggressiveness in Primary Mediastinal B-Cell Lymphoma . Blood vol. 128 , ( 22 ) 609 - 609 .

Stunnenberg HG, Abrignani S, Adams D, de Almeida M, Altucci L, Amin V, Amit I, Antonarakis SE et al. ( 2016 ) . The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery . Cell vol. 167 , ( 5 ) 1145 - 1149 .

Mansouri L, Noerenberg D, Young E, Mylonas E, Abdulla M, Frick M, Asmar F, Ljungström V et al. ( 2016 ) . Frequent NFKBIE deletions are associated with poor outcome in primary mediastinal B-cell lymphoma . Blood vol. 128 , ( 23 ) 2666 - 2670 .

Araf S, Korfi K, Rahim T, Davies A, Fitzgibbon J ( 2016 ) . Advances in the molecular diagnosis of diffuse large B-cell lymphoma in the era of precision medicine . Expert Review of Molecular Diagnostics: new diagnostic technologies are set to revolutionise healthcare vol. 16 , ( 10 ) 1093 - 1102 .

Araf S, Fitzgibbon J ( 2016 ) . Pediatric-type FL: Simply different . Blood vol. 128 , ( 8 ) 1030 - 1031 .

Ripperger T, Tawana K, Kratz C, Schlegelberger B, Fitzgibbon J, Steinemann D ( 2016 ) . Clinical utility gene card for: Familial platelet disorder with associated myeloid malignancies . European Journal of Human Genetics vol. 24 , ( 8 ) e1 - e4 .

Tummala H, Walne AJ, Williams M, Bockett N, Collopy L, Cardoso S, Ellison A, Wynn R et al. ( 2016 ) . DNAJC21 Mutations Link a Cancer-Prone Bone Marrow Failure Syndrome to Corruption in 60S Ribosome Subunit Maturation . American Journal of Human Genetics vol. 99 , ( 1 ) 115 - 124 .

Larrea E, Fernandez-Mercado M, Ceberio I, Guerra-Assunção JA, Okosun J, Fitzgibbon J, Lawrie C ( 2016 ) . 110 Follicular lymphoma cases harbour recurrent mutations in micro-RNA binding sites of genes associated with lymphomagenesis . European Journal of Cancer vol. 61 , s11 - s12 .

Larrea E, Fernandez-Mercado M, Ceberio I, Guerra-Assuncao JA, Okosun J, Fitzgibbon J, Lawrie C ( 2016 ) . Follicular lymphoma cases harbour recurrent mutations in microRNA binding sites of genes associated with lymphomagenesis . EUROPEAN JOURNAL OF CANCER . vol. 61 , S11 - S12 .

GROSE RP, Dawkins JBN, Wang J, maniati, heward, koniali, kocher, martin et al. ( 2016 ) . Reduced expression of histone methyltransferases KMT2C and KMT2D correlates with improved outcome in pancreatic ductal adenocarcinoma . Cancer Research

Araf S, Wang J, Pangault C, Kotsiou E, Hoxha E, Iqbal S, Davies J, Johnson P et al. ( 2016 ) . GENOMIC PROFILING REVEALS SPATIAL HETEROGENEITY IN FOLLICULAR LYMPHOMA: IMPLICATIONS FOR PRECISION MEDICINE . HAEMATOLOGICA . vol. 101 , 270 - 270 .

Britton D, Casado P, Rajeeve V, Wilkes E, Smith R, Fitzgibbon J, Gribben J, Cutillas P ( 2016 ) . PROTEOMIC ANALYSIS OF RELAPSE AML IDENTIFIES OPPORTUNITIES FOR THERAPEUTIC INTERVENTION IN INDIVIDUAL PATIENTS . HAEMATOLOGICA . vol. 101 , 373 - 373 .

Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al. ( 2016 ) . Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma (vol 48, pg 183, 2016) . NATURE GENETICS vol. 48 , ( 6 ) 700 - 700 .

Rio-Machin A, Cardoso S, Tawana K, Wang J, Chelala C, Plagnol V, Wallis Y, Ryan G et al. ( 2016 ) . WHOLE EXOME SEQUENCING REVEALS NOVEL CANDIDATE GENES IN FAMILIAL MDS/AML . HAEMATOLOGICA . vol. 101 , 205 - 206 .

Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Seraihi AFA et al. ( 2016 ) . Corrigendum: Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma . Nat Genet vol. 48 , ( 6 ) 700 - 700 .

DOKAL I ( 2016 ) . Germline heterozygous DDX41 vriants in a subset of familial myelodysplasia and acute myeloid leukaemia . Leukemia

Okosun J, Montoto S, Fitzgibbon J ( 2016 ) . The routes for transformation of follicular lymphoma . Current Opinion in Hematology vol. 23 , ( 4 ) 1 - 1 .

Kotsiou E, Okosun J, Besley C, Iqbal S, Matthews J, Fitzgibbon J, Gribben J, DAVIES JK ( 2016 ) . TNFRSF14 aberrations in follicular lymphoma increase clinically significant allogeneic T-cell responses . Blood vol. 128 , ( 1 ) 72 - 81 .

Strefford JC, Fitzgibbon J, Rose-Zerilli MJJ, Bödör C ( 2016 ) . The genetics of mature B-cell malignancies . The Genetic Basis of Haematological Cancers ,

Tawana K, Fitzgibbon J ( 2016 ) . Inherited DDX41 mutations: 11 genes and counting . Blood vol. 127 , ( 8 ) 960 - 961 .

Klapper W, Klein U, De Silva NS, Zha S, Crowe JL, Dai B, Weilemann A, Okosun J et al. ( 2016 ) . 5. Follicular lymphoma . Malignant Lymphomas ,

Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al. ( 2016 ) . Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma . Nature Genetics vol. 48 , ( 2 ) 183 - 188 .

Engert A, Balduini C, Brand A, Coiffier B, Cordonnier C, Döhner H, De Wit TD, Eichinger S et al. ( 2016 ) . The european hematology association roadmap for european hematology research: A consensus document . Haematologica vol. 101 , ( 2 ) 115 - 208 .

Araf S, Okosun J, Koniali L, Fitzgibbon J, Heward J ( 2016 ) . Epigenetic dysregulation in follicular lymphoma . Epigenomics vol. 8 , ( 1 ) 77 - 84 .

Okosun J, Fitzgibbon J ( 2016 ) . Follicular lymphoma . Malignant Lymphomas: Biology and Molecular Pathogenesis ,

Okosun J, Wolfson RL, Wang J, Araf S, Wilkins L, Castellano BM, Escudero-Ibarz L, Al Seraihi AF et al. ( 2015 ) . Recurrent mTORC1-activating RRAGC mutations in follicular lymphoma . Nature Genetics .

Tawana K, Wang J, Renneville A, Bödör C, Hills R, Loveday C, Savic A, Van Delft FW et al. ( 2015 ) . Disease evolution and outcomes in familial AML with germline CEBPA mutations . Blood vol. 126 , ( 10 ) 1214 - 1223 .

Carlotti E, Wrench D, Rosignoli G, Marzec J, Sangaralingam A, Hazanov L, Michaeli M, Hallam S et al. ( 2015 ) . High throughput sequencing analysis of the immunoglobulin heavy chain gene from flow-sorted B cell sub-populations define the dynamics of follicular lymphoma clonal evolution . PLoS ONE vol. 10 , ( 9 )

Tawana K, Wang J, Kiraly PA, Kallay K, Benyo G, Krivan G, Csomor J, Fitzgibbon J et al. ( 2015 ) . CONVERGENCE OF SOMATIC MUTATIONS WITHIN THE JAK-STAT SIGNALLING PATHWAY IN A NOVEL RUNX1-MUTATED PEDIGREE . HAEMATOLOGICA . vol. 100 , 9 - 10 .

Koniali L, Heward J, Loveday C, Wilkins L, Ishfaq M, Wang J, Okosun J, Packham G et al. ( 2015 ) . KDM5 INHIBITION LEADS TO INCREASED H3K4ME3 LEVELS AND CELL DEATH IN GERMINAL CENTRE LYMPHOMA CELL LINES INDEPENDENT OF MLL2 MUTATION STATUS . HAEMATOLOGICA . vol. 100 , 104 - 104 .

Noerenberg D, Frick M, Couronne L, Lenze D, Baldus CD, Bastard C, Okosun J, Fitzgibbon J et al. ( 2015 ) . NFKBIE MUTATIONS OCCUR IN 15% OF GCB DLBCL AND IN VARIOUS OTHER LYMPHOID MALIGNANCIES . HAEMATOLOGICA . vol. 100 , 549 - 549 .

Kotsiou E, Okosun J, Clear AJ, Iqbal S, Fitzgibbon J, Gribben JG, Davies JK ( 2014 ) . TNFRSF14 aberrations in Follicular Lymphoma B Cells Result in Increased Alloresponses in Vitro and in Vivo . Blood . vol. 124 , 2426 - 2426 .

Haider S, Wang J, Nagano A, Desai A, Arumugam P, Dumartin L, Fitzgibbon J, Hagemann T et al. ( 2014 ) . A multi-gene signature predicts outcome in patients with pancreatic ductal adenocarcinoma . Genome Medicine vol. 6 , ( 12 )

Rohatiner AZS, Smith ML, Spinelli O, Rambaldi A, Bassan R, di Bona E, Rodeghiero F, Raimondi R et al. ( 2014 ) . Myeloblative therapy with autologous haematopoietic stem cell support as consolidation of first remission in acute myeloid leukaemia - very long follow-up . British Journal of Haematology vol. 167 , ( 5 ) 724 - 726 .

Okosun J, Packham G, Fitzgibbon J ( 2014 ) . Investigational epigenetically targeted drugs in early phase trials for the treatment of haematological malignancies . Expert Opin Investig Drugs vol. 23 , ( 10 ) 1321 - 1332 .

Bouska A, McKeithan TW, Deffenbacher KE, Lachel C, Wright GW, Iqbal J, Smith LM, Zhang W et al. ( 2014 ) . Genome-wide copy-number analyses reveal genomic abnormalities involved in transformation of follicular lymphoma . BLOOD vol. 123 , ( 11 ) 1681 - 1690 .

Okosun J, Bödör C, Wang J, Araf S, Yang CY, Pan C, Boller S, Cittaro D et al. ( 2014 ) . Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma . Nature Genetics vol. 46 , ( 2 ) 176 - 181 .

Okosun J, Bödör C, Wang J, Araf S, Yang C-Y, Pan C, Boller S, Cittaro D et al. ( 2014 ) . Integrated genomic analysis identifies recurrent mutations and evolution patterns driving the initiation and progression of follicular lymphoma . Nat Genet vol. 46 , ( 2 ) 176 - 181 .

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Fitzgibbon J, Smith M, Arch R, Smith LL, Bainton N, Neat M, Bonnet D, Cavenagh J et al. ( 2004 ) . Development of a human acute myeloid leukaemia screening panel and identification of novel gene mutations . BLOOD . vol. 104 , 817A - 817A .

Ridler C, Smith M, Milne T, Ebrahim F, Macey M, Lister TA, Fitzgibbon J, Cavenagh JD et al. ( 2004 ) . Flow cytometric FLT3 expression in acute leukaemias is of diagnostic value but does not correlate with ITD/D835Y mutation status . BLOOD . vol. 104 , 823A - 823A .

Fitzgibbon J, Smith M, Cavenagh J, Lister TA ( 2004 ) . Mutation of CEBPA in familial acute myeloid leukaemia . BLOOD . vol. 104 , 555A - 555A .

Davies AJ, Lee AM, Taylor C, Clear AJ, Goff LK, Iqbal S, Cuthbert-Heavens D, Calaminici M et al. ( 2004 ) . Sequential Time-Point Mutational Analysis of TP53 in Follicular Lymphoma Undergoing Transformation to Large B-Cell Lymphoma . Blood vol. 104 , ( 11 ) 1361 - 1361 .

Davies AJ, Lee AM, Taylor C, Clear AJ, Goff LK, Iqbal S, Cuthbert-Heavens D, Calaminici M et al. ( 2004 ) . Sequential time-point mutational analysis of TP53 in follicular lymphoma undergoing transformation to large B-cell lymphoma . BLOOD . vol. 104 , 382A - 382A .

Last K, Perry J, Maharaj L, Strauss S, Davies A, Skoulakis S, Fitzgibbon J, Lister A et al. ( 2004 ) . The induction of apoptosis in lymphoma cells by methylseleninic acid and selenodiglutathione . BLOOD . vol. 104 , 686A - 686A .

Lee A, Davies A, Clear A, Calaminici M, Matthews J, Norton A, Wright G, Staudt LM et al. ( 2004 ) . Tissue microarray is a useful tool in the evaluation of genes implicated in transformation of follicular lymphoma . BLOOD . vol. 104 , 624A - 624A .

Last KW, Rohatiner AZS, Fitzgibbon J, Lister TA ( 2004 ) . Serum selenium in lymphoma - In reply . J CLIN ONCOL vol. 22 , ( 16 ) 3430 - 3430 .

Nilsen H, An Q, Fitzgibbon J, Lister A, Lindahl T ( 2004 ) . Complex phenotypes associated with uracil in DNA in mammals . BRITISH JOURNAL OF CANCER . vol. 91 , S71 - S71 .

Iqbal S, Jenner MJR, Summers KE, Davies AJ, Matthews J, Norton AJ, Calaminici M, Rohatiner AZ et al. ( 2004 ) . Reliable detection of clonal IgH/Bcl2 MBR rearrangement in follicular lymphoma: methodology and clinical significance . Br J Haematol vol. 124 , ( 3 ) 325 - 328 .

Goff LK, Iqbal S, Jenner MJ, Summers KE, Matthews J, Norton AJ, Calaminici M, Rohatiner AZS et al. ( 2003 ) . Reliable detection of clonal IgH/Bcl-2 MBR rearrangement in follicular lymphoma: Methodology and clinical significance . BLOOD . vol. 102 , 633A - 633A .

Debernardi S, Van Delft F, Davies A, Lillington D, Smith M, Lister TA, Saha V, Young BD et al. ( 2003 ) . The Wiskott-Aldrich-Syndrome family member 1 (WASF1) gene on 6q21 is down-regulated in specific AML cytogenetic subtypes . BLOOD . vol. 102 , 582A - 582A .

Last KW, Cornelius V, Delves T, Sieniawska C, Fitzgibbon J, Norton A, Amess J, Wilson A et al. ( 2003 ) . Presentation serum selenium predicts for overall survival, dose delivery, and first treatment response in aggressive non-Hodgkin's lymphoma . J Clin Oncol vol. 21 , ( 12 ) 2335 - 2341 .

Snaddon J, Smith ML, Neat M, Cambal-Parrales M, Dixon-McIver A, Arch R, Amess JA, Rohatiner AZ et al. ( 2003 ) . Mutations of CEBPA in acute myeloid leukemia FAB types M1 and M2 . Genes Chromosomes Cancer vol. 37 , ( 1 ) 72 - 78 .

Smith ML, Snaddon J, Neat M, Cambal-Parrales M, Arch R, Lister TA, Fitzgibbon J ( 2003 ) . Mutation of BRAF is uncommon in AML FAB type M1 and M2 . LEUKEMIA vol. 17 , ( 1 ) 274 - 275 .

Davies A, Rosenwald A, Wright G, Henrickson SE, Hong Z, Fitzgibbon J, Last K, Norton A et al. ( 2002 ) . Gene expression profiling in paired follicular lymphoma samples pre- and post-transformation to large B cell lymphoma . BLOOD . vol. 100 , 315A - 316A .

Jenner M, Summers K, Matthews J, Bradburn M, Dunning A, Wilson G, Lister TA, Fitzgibbon J ( 2002 ) . Genetic risk factor for follicular lymphoma within the MHC region . BLOOD . vol. 100 , 567A - 567A .

Fitzgibbon J, Arch R, Davies A, Snaddon J, Neat M, Foot N, Summers K, Goff L et al. ( 2002 ) . Refinement and evaluation of candidate genes within the 13q amplicon in germinal centre lymphoma . BLOOD . vol. 100 , 189B - 190B .

Jenner MJ, Summers KE, Norton AJ, Amess JA, Arch RS, Young BD, Lister TA, Fitzgibbon J et al. ( 2002 ) . JH probe real-time quantitative polymerase chain reaction assay for Bcl-2/IgH rearrangements . Br J Haematol vol. 118 , ( 2 ) 550 - 558 .

Summers KE, Davies AJ, Matthews J, Jenner MJ, Cornelius V, Amess JA, Norton AJ, Rohatiner AZS et al. ( 2002 ) . The relative role of peripheral blood and bone marrow for monitoring molecular evidence of disease in follicular lymphoma by quantitative real-time polymerase chain reaction . Br J Haematol vol. 118 , ( 2 ) 563 - 566 .

Snaddon J, Neat M, Fitzgibbon J, Smith ML, Rohatiner AZ, Lister TA, Amess JA ( 2002 ) . Mutations in the runt homology domain of CBFalpha2 in myeloid malignancies with acquired trisomy 21 . Cancer Genet Cytogenet vol. 136 , ( 2 ) 151 - 152 .

Summers KE, Goff LK, Wilson AG, Gupta RK, Lister TA, Fitzgibbon J ( 2001 ) . The frequency of the Bcl-2/IgH t(14;18)(q32;q21) rearrangement in normal individuals implications for the monitoring of disease in patients with follicular lymphoma . LEUKEMIA vol. 15 , ( 12 ) 2024 - 2024 .

Jenner MJ, Summers KE, Norton AJ, Amess JA, Arch RS, Young BD, Lister TA, Fitzgibbon J et al. ( 2001 ) . A universal strategy for quantifying Bcl-2/IgH breakpoints in follicular lymphoma . BLOOD vol. 98 , ( 11 ) 126A - 126A .

Snaddon J, Arch R, Sutcliffe K, Lister TA, Fitzgibbon J ( 2001 ) . Identification of several novel polymorphisms in the low affinity FC inhibitory receptor FCGR2B . BLOOD vol. 98 , ( 11 ) 164B - 164B .

Snaddon J, Neat M, Smith ML, Rohatiner AZ, Lister TA, Fitzgibbon J ( 2001 ) . Mutations in the runt domain of CBFA2 in myeloid malignancies with acquired trisomy 21 . BLOOD vol. 98 , ( 11 ) 195B - 195B .

Snaddon J, Smith ML, Neat M, Arch R, Cambal-Parrales M, Amess JA, Rohatiner AZ, Lister TA et al. ( 2001 ) . Mutations of CEBPA in acute myeloid leukaemia FAB-type M1 and M2 . BLOOD vol. 98 , ( 11 ) 195B - 195B .

Davies AJ, Summers KE, Matthews J, Jenner MJ, Amess JA, Norton AJ, Rohatiner AZ, Fitzgibbon J et al. ( 2001 ) . The relative role of peripheral blood and bone marrow for monitoring molecular evidence of disease in follicular lymphoma by quantitative real time PCR . BLOOD vol. 98 , ( 11 ) 124A - 125A .

Neat MJ, Foot N, Jenner M, Goff L, Ashcroft K, Burford D, Dunham A, Norton A et al. ( 2001 ) . Localisation of a novel region of recurrent amplification in, follicular lymphoma to an similar to 6.8 Mb region of 13q32-33 . GENE CHROMOSOME CANC vol. 32 , ( 3 ) 236 - 243 .

Foot N, Neat M, Jenner M, Goff L, Dunham I, Ross M, Fitzgibbon J, Lister TA ( 2001 ) . Localisation of a novel region of amplification in follicular lymphoma tumours to a 24cR region of human chromosome 13 . J MED GENET vol. 38 , S44 - S44 .

Last KW, Cornelius V, Delves T, Fitzgibbon J, Wilson A, Rohatiner AZS, Lister TA ( 2001 ) . Presentation serum selenium predicts for overall survival in patients with diffuse large B-cell (DLBC) lymphoma . BRIT J CANCER vol. 85 , 59 - 59 .

Summers KE, Goff LK, Wilson AG, Gupta RK, Lister TA, Fitzgibbon J ( 2001 ) . Frequency of the Bcl-2/IgH rearrangement in normal individuals: implications for the monitoring of disease in patients with follicular lymphoma . J Clin Oncol vol. 19 , ( 2 ) 420 - 424 .

Fitzgibbon J, Hill AS, Arch RS ( 2000 ) . Identification of a novel polymorphism in the human FCGR2B gene: Correlation with response to rituximab treatment in patients with follicular lymphoma . Blood vol. 96 , ( 11 PART II )

Jenner MJ, Matthews J, Summers K, Young BD, Fitzgibbon J, Lister A ( 2000 ) . Application of real time PCR to establishing clonality of Bcl-2 rearrangements in patients with follicular lymphoma . BLOOD vol. 96 , ( 11 ) 332A - 332A .

Fitzgibbon J, Hill AS, Arch RS, Sutcliffe C, Summers KE, Lister A ( 2000 ) . Identification of a novel polymorphism in the human FCGR2B gene: Correlation with response to Rituximab treatment in patients with follicular lymphoma . BLOOD vol. 96 , ( 11 ) 179B - 179B .

Neat M, Foot N, Jenner M, Goff L, Ashcroft K, Burford D, Dunham A, Fitzgibbon J et al. ( 2000 ) . Localisation of a novel region of amplification in follicular lymphoma to an similar to 6.8 Mb region of human chromosome 13q32-33 . BLOOD vol. 96 , ( 11 ) 87A - 87A .

Last KW, Cornelius VR, Delves T, Fitzgibbon J, Wilson A, Rohatiner AZ, Lister A ( 2000 ) . Presentation serum selenium predicts for overall survival in patients with diffuse large B-cell (DLBC) lymphoma . BLOOD vol. 96 , ( 11 ) 335A - 335A .

Last KW, Goff LK, Summers KE, Neat M, Jenner M, Crawley C, Rohatiner AZ, Fitzgibbon J et al. ( 2000 ) . Familial follicular lymphoma: A case report with molecular analysis [2] . British Journal of Haematology vol. 110 , ( 3 ) 744 - 745 .

Fitzgibbon J, Neat MJ, Jones L, Foot N, Lister TA, Gupta RK ( 2000 ) . Assignment of B-cell lymphoma 6, member B (zinc finger protein) gene (BCL6B) to human chromosome 17p13.1 by in situ hybridization . Cytogenetics and Cell Genetics vol. 89 , ( 3-4 ) 218 - 219 .

Fitzgibbon J, Neat MJ, Foot N, Hill AS, Lister TA, Gupta RK ( 2000 ) . Assignment of brain acid-soluble protein 1 (BASP1) to human chromosome 5p15.1· p14, differential expression in human cancer cell lines as a result of alterations in gene dosage . Cytogenetics and Cell Genetics vol. 89 , ( 3-4 ) 147 - 149 .

Fitzgibbon J, Grenzelias D, Matthews J, Andrew Lister T, Gupta RK ( 1999 ) . Tumour necrosis factor polymorphisms and susceptibility to follicular lymphoma . British Journal of Haematology vol. 107 , ( 2 ) 388 - 391 .

Halford S, Dulai KS, Daw SC, Fitzgibbon J, Hunt DM ( 1998 ) . Isolation and chromosomal localization of two human CDP-diacylglycerol synthase (CDS) genes . Genomics vol. 54 , ( 1 ) 140 - 144 .

Hunt DM, Fitzgibbon J, Slobodyanyuk SJ, Bowmaker JK, Dulai KS ( 1997 ) . Molecular Evolution of the Cottoid Fish Endemic to Lake Baikal Deduced from Nuclear DNA Evidence . Molecular Phylogenetics and Evolution vol. 8 , ( 3 ) 415 - 422 .

Katsanis N, Fitzgibbon J, Fisher EMC ( 1996 ) . Paralogy mapping: Identification of a region in the human MHC triplicated onto human chromosomes 1 and 9 allows the prediction and isolation of novel PBX and NOTCH loci . Genomics vol. 35 , ( 1 ) 101 - 108 .

Fitzgibbon J, Katsanis N, Wells D, Delhanty J, Vallins W, Hunt DM ( 1996 ) . Human guanylate kinase (GUK1): cDNA sequence, expression and chromosomal localisation . FEBS Letters vol. 385 , ( 3 ) 185 - 188 .

Hunt DM, Fitzgibbon J, Slobodyanyuk SJ, Bowmaker JK ( 1996 ) . Spectral tuning and molecular evolution of rod visual pigments in the species flock of cottoid fish in Lake Baikal . Vision Research vol. 36 , ( 9 ) 1217 - 1224 .

Fitzgibbon J, Hope A, Slobodyanyuk SJ, Bellingham J, Bowmaker JK, Hunt DM ( 1995 ) . The rhodopsin-encoding gene of bony fish lacks introns . Gene vol. 164 , ( 2 ) 273 - 277 .

Woodward K, Nahmias J, Hornigold N, West L, Pilz A, Benham F, Kwiatkowski D, Fitzgibbon J et al. ( 1995 ) . Regional localization of 64 cosmid contigs, including 18 genes and 14 markers, to intervals on human chromosome 9q34 . Genomics vol. 29 , ( 1 ) 257 - 260 .

Pilz A, Schaap D, Hunt D, Fitzgibbon J ( 1995 ) . Chromosomal localization of three mouse diacylglycerol kinase (DAGK) genes: genes sharing sequence homology to the Drosophila retinal degeneration A (rdgA) gene . Genomics vol. 26 , ( 3 ) 599 - 601 .

Nahmias J, Hornigold N, Fitzgibbon J, Woodward K, Pilz A, Griffin D, Henske EP, Nakamura Y et al. ( 1995 ) . Cosmid contigs spanning 9q34 including the candidate region for TSC1 . European Journal of Human Genetics vol. 3 , ( 2 ) 65 - 77 .

Fitzgibbon J, Wells D, Pilz A, Delhanty J, Kai M, Kanoh H, Hunt D ( 1995 ) . Localisation of the gene encoding diacylglycerol kinase 3 (DAGK3) to human chromosome 3q27-28 and mouse chromosome 16 . Current Eye Research vol. 14 , ( 11 ) 1041 - 1043 .

Fitzgibbon J, Appukuttan B, Gayther S, Wells D, Delhanty J, Hunt DM ( 1994 ) . Localisation of the human blue cone pigment gene to chromosome band 7q31.3-32 . Human Genetics vol. 93 , ( 1 ) 79 - 80 .

Fitzgibbon J, Pilz A, Gayther S, Appukuttan B, Dulai KS, Delhanty JDA, Helmkamp GM, Yarbrough LR et al. ( 1994 ) . Localization of the gene encoding human phosphatidylinositol transfer protein (PITPIM) to 17p13.3: A gene showing homology to the Drosophila retinal degeneration B gene (rdgB) . Cytogenetic and Genome Research vol. 67 , ( 3 ) 205 - 207 .

JONES KA, FITZGIBBON J, WOODWARD KJ, GOUDIE D, FERGUSON‐SMITH MA, POVEY S, WOLFE J, SOLOMON E ( 1993 ) . Localization of the retinoid X receptor alpha gene (RXRA) to chromosome 9q34 . Annals of Human Genetics vol. 57 , ( 3 ) 195 - 201 .

FITZGIBBON J, GILLETT GT, WOODWARD KJ, BOYLE JM, WOLFE J, POVEY S ( 1993 ) . Mapping of RXRB to human chromosome 6p21. 3 . Annals of Human Genetics vol. 57 , ( 3 ) 203 - 209 .

Degen SJF, Schaefer LA, Jamison CS, Grant SG, Fitzgibbon JJ, Pai JA, Chapman VM, Elliott RW ( 1990 ) . Characterization of the cDNA Coding for Mouse Prothrombin and Localization of the Gene on Mouse Chromosome 2 . DNA and Cell Biology vol. 9 , ( 7 ) 487 - 498 .