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Research

Publications: Dr Jane Sosabowski

Borràs J, Foster J, Kashani R, Meléndez-Alafort L, Sosabowski J, Suades J, Barnadas-Rodríguez R ( 2021 ) . New bioconjugated technetium and rhenium folates synthesized by transmetallation reaction with zinc derivatives . Molecules vol. 26 , ( 8 )
Borràs J, Lecina J, Foster J, Kashani R, Melendez-Alafort L, Sosabowski J, Suades J ( 2021 ) . Bioconjugated technetium carbonyls by transmetalation reaction with zinc derivatives . Bioorganic and Medicinal Chemistry Letters vol. 37 ,
Dexter K, BROWN N, Foster J, Kashani R, CHUPIN J, Cleaver J, Cutmore L, Marshall J et al. ( 2020 ) . Simultaneous dual isotope PET-SPECT/CT imaging of pancreatic cancer . Presented at: EMIM 2020 , Abstract: java.sql.Clob org.hibernate.engine.jdbc.WrappedClob java.io.Serializable ,
Demircioglu F, Wang J, Candido J, Costa ASH, Casado P, de Luxan Delgado B, Reynolds LE, Gomez-Escudero J et al. ( 2020 ) . Cancer associated fibroblast FAK regulates malignant cell metabolism . Nature Communications vol. 11 , ( 1 ) 1290 - 1290 .
Wang JTW, Klippstein R, Martincic M, Pach E, Feldman R, Šefl M, Michel Y, Asker D et al. ( 2020 ) . Neutron Activated <sup>153</sup>Sm Sealed in Carbon Nanocapsules for in Vivo Imaging and Tumor Radiotherapy . ACS Nano vol. 14 , ( 1 ) 129 - 141 .
Kee CW, Tack O, Guibbal F, Wilson TC, Isenegger PG, Imiołek M, Verhoog S, Tilby M et al. ( 2020 ) . 18F-Trifluoromethanesulfinate Enables Direct C–H 18F-Trifluoromethylation of Native Aromatic Residues in Peptides . Journal of the American Chemical Society vol. 142 , ( 3 ) 1180 - 1185 .
Wang JTW, Hodgins NO, Al-Jamal WT, Maher J, Sosabowski JK, Al-Jamal KT ( 2020 ) . Organ biodistribution of radiolabelled δγ t cells following liposomal alendronate administration in different mice tumour models . Nanotheranostics vol. 4 , ( 2 ) 71 - 82 .
Stella Man YK, Foster J, Carapuça E, Davies JA, Parker AL, Sosabowski J, Halldén G ( 2019 ) . Systemic delivery and SPECT/CT in vivo imaging of <sup>125</sup>I-labelled oncolytic adenoviral mutants in models of pancreatic cancer . Scientific Reports vol. 9 , ( 1 )
Wang J, Kafa H, Rubio N, Bansal S, Festy F, Sosabowski J, Abbott J, Al-Jamal K ( 2019 ) . Functionalised LRP1 targeted carbon nanotubes across the blood-brain barrier in vitro and in vivo after intravenous injection . Neuro-Oncology . vol. 21 , iv3 - iv3 .
Crnogorac-Jurcevic T, Radon T, Shah S, Weeks M, Foster J, Sosabowski J, Dumartin L ( 2019 ) . AGR2, a unique tumor-associated antigen, is a promising candidate for antibody targeting . Oncotarget
Martinez O, Sosabowski J, Maher J, Papa S ( 2019 ) . New developments in imaging cell-based therapy . Journal of Nuclear Medicine vol. 60 , ( 6 ) 730 - 735 .
Zhai C, He S, Chen X, Lu J, Rangger C, Summer D, Haas H, Foster J et al. ( 2019 ) . Synthesis and comparison of novel fusarinine C-based chelators for Zr-89-labeling . JOURNAL OF LABELLED COMPOUNDS & RADIOPHARMACEUTICALS . vol. 62 , S35 - S36 .
Zhai C, He S, Ye Y, Rangger C, Kaeopookum P, Summer D, Haas H, Kremser L et al. ( 2019 ) . Rational design, synthesis and preliminary evaluation of novel fusarinine C-based chelators for radiolabeling with Zirconium-89 . Biomolecules vol. 9 , ( 3 )
Klingler M, Summer D, Rangger C, Haubner R, Foster J, Sosabowski J, Decristoforo C, Virgolini I et al. ( 2019 ) . DOTA-MGS5, a new cholecystokinin-2 receptor-targeting peptide analog with an optimized targeting profile for theranostic use . Journal of Nuclear Medicine vol. 60 , ( 7 ) 1010 - 1016 .
Klingler M, Decristoforo C, Rangger C, Summer D, Foster J, Sosabowski JK, Von Guggenberg E ( 2019 ) . Erratum: Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting (Theranostics(2018) 8:11 (2896-2908) DOI: 10.7150/thno.24378) . Theranostics vol. 9 , ( 16 ) 4595 - 4596 .
Faruqu FN, Wang JTW, Xu L, McNickle L, Chong EMY, Walters A, Gurney M, Clayton A et al. ( 2019 ) . Membrane radiolabelling of exosomes for comparative biodistribution analysis in immunocompetent and immunodeficient mice – A novel and universal approach . Theranostics vol. 9 , ( 6 ) 1666 - 1682 .
Rudran B, Reader C, Foster J, Hodivala-Dilke K, Sosabowski J, Marshall J ( 2018 ) . P1.03-19 Antibody Blockade of Integrin Alpha-V-Beta-6 (avb6) as a Novel Treatment for NSCLC . Journal of Thoracic Oncology . vol. 13 , s518 - s519 .
Pouget J, Deshayes E, Ladjohounlou R, le Fur P, Pichard A, Lozza C, Kashani R, Koch J et al. ( 2018 ) . Theranostic approach in ovarian cancer using Anti-MISRII radiolabeled antibodies . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 45 , S616 - S617 .
Deshayes E, Ladjohounlou R, Le Fur P, Pichard A, Lozza C, Boudousq V, Sevestre S, Jarlier M et al. ( 2018 ) . Radiolabeled antibodies against Müllerian-inhibiting substance receptor, type II: New tools for a theranostic approach in ovarian cancer . Journal of Nuclear Medicine vol. 59 , ( 8 ) 1234 - 1242 .
Klingler M, Decristoforo C, Rangger C, Summer D, Foster J, Sosabowski JK, von Guggenberg E ( 2018 ) . Site-specific stabilization of minigastrin analogs against enzymatic degradation for enhanced cholecystokinin-2 receptor targeting . Theranostics vol. 8 , ( 11 ) 2896 - 2908 .
Emami-Shahri N, Foster J, Kashani R, Gazinska P, Cook C, Sosabowski J, Maher J, Papa S ( 2018 ) . Clinically compliant spatial and temporal imaging of chimeric antigen receptor T-cells . Nature Communications vol. 9 , ( 1 ) 1081 - 1081 .
Rudran B, Reader C, Foster J, Hodivala-Dilke K, Sosabowski J, Marshall J ( 2018 ) . 12 Blockade of integrin alpha-v-beta-6 (αvβ6) reduces the invasive potential of NSCLC . Lung Cancer vol. 115 , s5 - s6 .
Tremoleda JL, Macholl S, Sosabowski JK ( 2018 ) . Anesthesia and monitoring of animals during MRI studies . Methods in Molecular Biology , vol. 1718 ,
Rudran B, Reader C, Foster J, Hodivala-Dilke K, Sosabowski J, Marshall J ( 2018 ) . Blockade of integrin alpha-v-beta-6 (alpha v beta 6) reduces the invasive potential of NSCLC . LUNG CANCER . vol. 115 , S5 - S6 .
Costa PM, Wang JTW, Morfin JF, Khanum T, To W, Sosabowski J, Tóth E, Al-Jamal KT ( 2018 ) . Functionalised carbon nanotubes enhance brain delivery of amyloid-targeting pittsburgh compound b (Pib)-derived ligands . Nanotheranostics vol. 2 , ( 2 ) 168 - 183 .
Ahmed W, Barker SA, Sosabowski J, Foster JM, Soanes R, Hartman N ( 2017 ) . Evaluation of the physicochemical properties of (99m)Technetium-Exametazime (Medi-Exametazime (TM)) and its biodistribution in a pre-clinical mouse model . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 44 , S544 - S544 .
Klingler M, Rangger C, Summer D, Foster J, Sosabowski JK, von Guggenberg E ( 2017 ) . New radiolabelled minigastrin analogues with improved CCK2R targeting for diagnostic and therapeutic use . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 44 , S228 - S228 .
Mak C, Barker SA, Sosabowski JK, Foster JM, Hartman NG ( 2017 ) . Stability assessment after reconstitution and investigation of the biodistribution in a pre-clinical mouse model of 99mTechnetium-Sestamibi (Cardiovis (TM)) . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 44 , S543 - S544 .
Hodgins NO, Al-Jamal WT, Wang JTW, Klippstein R, Costa PM, Sosabowski JK, Marshall JF, Maher J et al. ( 2017 ) . Investigating in vitro and in vivo αvβ6 integrin receptor-targeting liposomal alendronate for combinatory γδ T cell immunotherapy . Journal of Controlled Release vol. 256 , 141 - 152 .
Macholl S, Finucane CM, Hesterman J, Mather SJ, Pauplis R, Scully D, Sosabowski JK, Jouannot E ( 2017 ) . High-throughput high-volume nuclear imaging for preclinical in vivo compound screening§ . EJNMMI Res vol. 7 , ( 1 ) 33 - 33 .
Rudran B, Desai A, Luzarraga M, Hodivala-Dilke K, Foster J, Sosabowski J, Marshall J ( 2017 ) . Development of non-invasive imaging of integrin alpha-v-beta-6 (alpha v beta 6)-positive lung cancers in advance of testing alpha v beta 6-targeted therapies . Lung Cancer . Conference: British Thoracic Oncology Group Conference 2017 ( Dublin, Ireland ) from: 25/01/2017 to: 27/01/2017 , vol. 103 , S4 - S4 .
Rudran B, Desai A, Luzarraga M, Hodivala-Dilke K, Foster J, Sosabowski J, Marshall J ( 2017 ) . 6: Development of non-invasive imaging of integrin alpha-v-beta-6 (αvβ6)-positive lung cancers in advance of testing αvβ6-targeted therapies . Lung Cancer vol. 103 ,
Dubey RD, Klippstein R, Wang JTW, Hodgins N, Mei KC, Sosabowski J, Hider RC, Abbate V et al. ( 2017 ) . Novel hyaluronic acid conjugates for dual nuclear imaging and therapy in cd44-expressing tumors in mice in vivo . Nanotheranostics vol. 1 , ( 1 ) 59 - 79 .
Mohamed Suffian IFB, Wang JT-W, Hodgins NO, Klippstein R, Garcia-Maya M, Brown P, Nishimura Y, Heidari H et al. ( 2016 ) . Engineering hepatitis B virus core particles for targeting HER2 receptors in vitro and in vivo . Biomaterials vol. 120 , 126 - 138 .
Denis-Bacelar AM, Cronin SE, Da Pieve C, Paul RL, Eccles SA, Spinks TJ, Box C, Hall A et al. ( 2016 ) . Pre-clinical quantitative imaging and mouse-specific dosimetry for <sup>111</sup>In-labelled radiotracers . EJNMMI Research vol. 6 , ( 1 )
Paillas S, Ladjohounlou R, Lozza C, Pichard A, Boudousq V, Jarlier M, Deshayes E, Sosabowski J et al. ( 2016 ) . Localized irradiation of cell membrane by Auger electrons is cytotoxic through non-targeted effects involving p38 and JNK signaling pathways . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 43 , S163 - S164 .
Spinks TJ, Flux G, Sosabowski J, Finucane C, Macholl S ( 2016 ) . SPECT Characterisation and Quantification of Preclinical Scanners . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 43 , S524 - S524 .
Denis-Bacelar AM, Cronin SE, Da Pieve C, Paul R, Eccles SA, Spinks T, Box C, Hall A et al. ( 2016 ) . The effect of partial volume in quantitative pre-clinical imaging of In-111-labelled antibodies . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 43 , S490 - S490 .
Al-Jamal KT, Bai J, Wang JT-W, Protti A, Southern P, Bogart L, Heidari H, Li X et al. ( 2016 ) . Magnetic Drug Targeting: Preclinical in Vivo Studies, Mathematical Modeling, and Extrapolation to Humans . Nano Letters: a journal dedicated to nanoscience and nanotechnology
Emami-Shahri N, Foster J, Sosabowski J, Maher J, Papa S ( 2016 ) . Abstract 2315: Dynamic SPECT imaging of PSMA-specific CAR T cells in mice bearing prostate cancer . 2315 - 2315 .
Paillas S, Ladjohounlou R, Lozza C, Pichard A, Boudousq V, Jarlier M, Sevestre S, Le Blay M et al. ( 2016 ) . Localized Irradiation of Cell Membrane by Auger Electrons Is Cytotoxic Through Oxidative Stress-Mediated Nontargeted Effects . Antioxidants and Redox Signaling vol. 25 , ( 8 )
Tremoleda JL, Thau-Zuchman O, Davies M, Foster J, Khan I, Vadivelu KC, Yip PK, Sosabowski J et al. ( 2016 ) . In vivo PET imaging of the neuroinflammatory response in rat spinal cord injury using the TSPO tracer [18F]GE-180 and effect of docosahexaenoic acid . European Journal of Nuclear Medicine and Molecular Imaging
Cabana L, Bourgognon M, Wang JT-W, Protti A, Klippstein R, de Rosales RTM, Shah AM, Fontcuberta J et al. ( 2016 ) . The Shortening of MWNT-SPION Hybrids by Steam Treatment Improves Their Magnetic Resonance Imaging Properties In Vitro and In Vivo . Small vol. 12 , ( 21 ) 2893 - 2905 .
Kafa H, Wang JTW, Rubio N, Klippstein R, Costa PM, Hassan HAFM, Sosabowski JK, Bansal SS et al. ( 2016 ) . Translocation of LRP1 targeted carbon nanotubes of different diameters across the blood-brain barrier in vitro and in vivo . Journal of Controlled Release vol. 225 , 217 - 229 .
Wang JTW, Rubio N, Kafa H, Venturelli E, Fabbro C, Ménard-Moyon C, Da Ros T, Sosabowski JK et al. ( 2016 ) . Kinetics of functionalised carbon nanotube distribution in mouse brain after systemic injection: Spatial to ultra-structural analyses . Journal of Controlled Release vol. 224 , 22 - 32 .
Bai J, Wang JTW, Rubio N, Protti A, Heidari H, Elgogary R, Southern P, Al-Jamal WT et al. ( 2016 ) . Triple-modal imaging of magnetically-targeted nanocapsules in solid tumours in vivo . Theranostics vol. 6 , ( 3 ) 342 - 356 .
Tremoleda JL, Thau-Zuchman O, Davies M, Foster J, Khan I, Trigg W, Sosabowski J, Mather SJ et al. ( 2015 ) . IN VIVO IMAGING OF NEUROINFLAMMATION IN NEUROTRAUMA PRECLINICAL MODELS: POTENTIAL FOR CLINICAL TRANSLATION . SHOCK . vol. 44 , 24 - 25 .
Tremoleda JL, Thau-Zuchman O, Davies M, Foster J, Khan I, Trigg W, Sosabowski J, Mather SJ et al. ( 2015 ) . T-14: IN VIVO IMAGING OF NEUROINFLAMMATION IN NEUROTRAUMA PRECLINICAL MODELS&colon; POTENTIAL FOR CLINICAL TRANSLATION . Shock vol. 44 Suppl 2 , 24 - 25 .
Paillas S, Desai A, Quetier I, Marshall J, Pouget J, Sosabowski J ( 2015 ) . Targeted Radionuclide Therapy using high-LET particle emitter-labeled vectors against alpha-v-beta6-expressing cancers . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 42 , S201 - S201 .
Rycroft D, Sosabowski J, Coulstock E, Davies M, Morrey J, Friel S ( 2015 ) . Correction: Pharmacokinetic characteristics, pharmacodynamic effect and in vivo antiviral efficacy of liver-targeted interferon alpha . PLoS ONE vol. 10 , ( 4 )
Tremoleda JL, Sosabowski J ( 2015 ) . Imaging technologies and basic considerations for welfare of laboratory rodents . LAB ANIMAL vol. 44 , ( 3 ) 101 - 109 .
Tremoleda JL, Sosabowski J ( 2015 ) . Imaging technologies and basic considerations for welfare of laboratory rodents . Lab Animal vol. 44 , ( 3 ) 97 - 105 .
Rycroft D, Sosabowski J, Coulstock E, Davies M, Morrey J, Friel S, Kelly F, Hamatake R et al. ( 2015 ) . Pharmacokinetic characteristics, pharmacodynamic effect and in vivo antiviral efficacy of liver-targeted interferon alpha . PLoS ONE vol. 10 , ( 2 )
Goldstein R, Sosabowski J, Livanos M, Leyton J, Vigor K, Bhavsar G, Nagy-Davidescu G, Rashid M et al. ( 2015 ) . Development of the designed ankyrin repeat protein (DARPin) G3 for HER2 molecular imaging . Eur J Nucl Med Mol Imaging vol. 42 , ( 2 ) 288 - 301 .
Pujatti PB, Foster JM, Finucane C, Hudson CD, Burnet JC, Pasqualoto KFM, Mengatti J, Mather SJ et al. ( 2015 ) . Evaluation and comparison of a new DOTA and DTPA-bombesin agonist in vitro and in vivo in low and high GRPR expressing prostate and breast tumor models . Applied Radiation and Isotopes vol. 96 , 91 - 101 .
Parente-Pereira AC, Shmeeda H, Whilding LM, Zambirinis CP, Foster J, van der Stegen SJC, Beatson R, Zabinski T et al. ( 2014 ) . Adoptive immunotherapy of epithelial ovarian cancer with Vγ9Vδ2 T cells, potentiated by liposomal alendronic acid . J Immunol vol. 193 , ( 11 ) 5557 - 5566 .
Roosenburg S, Laverman P, Joosten L, Cooper MS, Kolenc-Peitl PK, Foster JM, Hudson C, Leyton J et al. ( 2014 ) . PET and SPECT imaging of a radiolabeled minigastrin analogue conjugated with DOTA, NOTA, and NODAGA and labeled with (64)Cu, (68)Ga, and (111)In . Mol Pharm vol. 11 , ( 11 ) 3930 - 3937 .
Wang JT-W, Fabbro C, Venturelli E, Ménard-Moyon C, Chaloin O, Da Ros T, Methven L, Nunes A et al. ( 2014 ) . The relationship between the diameter of chemically-functionalized multi-walled carbon nanotubes and their organ biodistribution profiles in vivo . Biomaterials vol. 35 , ( 35 ) 9517 - 9528 .
Da Pieve C, Cronin SE, Paul RL, Denis-Bacelar AM, Frisch KJ, Hall A, Sosabowski JK, Spinks T et al. ( 2014 ) . Pre-clinical image-based dosimetry using HER2 targeting In-111 labelled antibodies . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 41 , S281 - S281 .
Wang JTW, Cabana L, Bourgognon M, Kafa H, Protti A, Venner K, Shah AM, Sosabowski JK et al. ( 2014 ) . Magnetically decorated multiwalled carbon nanotubes as dual mri and spect contrast agents . Advanced Functional Materials vol. 24 , ( 13 ) 1880 - 1894 .
Allen MD, Luong P, Hudson C, Leyton J, Delage B, Ghazaly E, Cutts R, Yuan M et al. ( 2014 ) . Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging . Cancer Res vol. 74 , ( 3 ) 896 - 907 .
van der Stegen SJC, Davies DM, Wilkie S, Foster J, Sosabowski JK, Burnet J, Whilding LM, Petrovic RM et al. ( 2013 ) . Preclinical in vivo modeling of cytokine release syndrome induced by ErbB-retargeted human T cells: identifying a window of therapeutic opportunity? . J Immunol vol. 191 , ( 9 ) 4589 - 4598 .
Goldstein R, Tolner B, Leyton J, Livanos M, Bhavsar G, Vigor K, Nagy G, Mather S et al. ( 2013 ) . Pre-clinical developments of the G3 Designed ankyrin repeat protein (DARPin) for invivo assessment of HERZ expression . CANCER RESEARCH . vol. 73 ,
Goldstein R, Sosabowski J, Vigor K, Chester K, Meyer T ( 2013 ) . Developments in single photon emission computed tomography and PET-based HER2 molecular imaging for breast cancer . Expert Rev Anticancer Ther vol. 13 , ( 3 ) 359 - 373 .
Coulstock E, Sosabowski J, Ovečka M, Prince R, Goodall L, Mudd C, Sepp A, Davies M et al. ( 2013 ) . Liver-targeting of interferon-alpha with tissue-specific domain antibodies . PLoS One vol. 8 , ( 2 )
Wang JT-W, Cabana L, Bourgognon M, Kafa H, Protti A, Venner K, Shah AM, Sosabowski JK et al. ( 2013 ) . Magnetically Decorated Multiwalled Carbon Nanotubes as Dual MRI and SPECT Contrast Agents . Advanced Functional Materials
Rangger C, Helbok A, Sosabowski J, Kremser C, Koehler G, Prassl R, Andreae F, Virgolini IJ et al. ( 2013 ) . Tumor targeting and imaging with dual-peptide conjugated multifunctional liposomal nanoparticles . Int J Nanomedicine vol. 8 , 4659 - 4671 .
Joosten L, Sosabowski JK, Cooper MS, Foster J, Burnet J, Oyen WJG, Boerman OC, Blower PJ et al. ( 2012 ) . PET and SPECT Imaging of a CCK2 Receptor-Binding Peptide Comparing Various Chelators and Radionuclides . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 39 , S241 - S241 .
von Guggenberg E, Rangger C, Sosabowski J, Laverman P, Reubi J-C, Virgolini IJ, Decristoforo C ( 2012 ) . Preclinical evaluation of radiolabeled DOTA-derivatized cyclic minigastrin analogs for targeting cholecystokinin receptor expressing malignancies . Mol Imaging Biol vol. 14 , ( 3 ) 366 - 375 .
Laverman P, Sosabowski JK, Boerman OC, Oyen WJG ( 2012 ) . Radiolabelled peptides for oncological diagnosis . Eur J Nucl Med Mol Imaging vol. 39 Suppl 1 , S78 - S92 .
Rangger C, Helbok A, von Guggenberg E, Sosabowski J, Radolf T, Prassl R, Andreae F, Thurner GC et al. ( 2012 ) . Influence of PEGylation and RGD loading on the targeting properties of radiolabeled liposomal nanoparticles . Int J Nanomedicine vol. 7 , 5889 - 5900 .
Laverman P, Joosten L, Eek A, Roosenburg S, Peitl PK, Maina T, Mäcke H, Aloj L et al. ( 2011 ) . Comparative biodistribution of 12 ¹¹¹In-labelled gastrin/CCK2 receptor-targeting peptides . Eur J Nucl Med Mol Imaging vol. 38 , ( 8 ) 1410 - 1416 .
Ocak M, Helbok A, Rangger C, Peitl PK, Nock BA, Morelli G, Eek A, Sosabowski JK et al. ( 2011 ) . Comparison of biological stability and metabolism of CCK2 receptor targeting peptides, a collaborative project under COST BM0607 . Eur J Nucl Med Mol Imaging vol. 38 , ( 8 ) 1426 - 1435 .
Aloj L, Aurilio M, Rinaldi V, D'ambrosio L, Tesauro D, Peitl PK, Maina T, Mansi R et al. ( 2011 ) . Comparison of the binding and internalization properties of 12 DOTA-coupled and ¹¹¹In-labelled CCK2/gastrin receptor binding peptides: a collaborative project under COST Action BM0607 . Eur J Nucl Med Mol Imaging vol. 38 , ( 8 ) 1417 - 1425 .
Sosabowski J, Coulstock E, Walker A, Sepp A, Kashani R, Foster J, Burnet J, Prince R et al. ( 2011 ) . Biodistribution and microSPECT/CT imaging of In-111-radiolabelled dual targeted domain antibodies . JOURNAL OF NUCLEAR MEDICINE . vol. 52 ,
Sosabowski J, Finucane C, Foster J, Ellison D, Burnet J, Laverman P, Mather S ( 2011 ) . Comparative small animal SPECT/CT imaging of twelve In-111-labelled CCK2-receptor targeting peptides . JOURNAL OF NUCLEAR MEDICINE . vol. 52 ,
Finucane CM, Murray I, Sosabowski JK, Foster JM, Mather SJ ( 2011 ) . Quantitative Accuracy of Low-Count SPECT Imaging in Phantom and In Vivo Mouse Studies . Int J Mol Imaging vol. 2011 ,
Naqvi SAR, Sosabowski JK, Nagra SA, Ishfaq MM, Mather SJ, Matzow T ( 2011 ) . Radiopeptide internalisation and externalization assays: cell viability and radioligand integrity . Appl Radiat Isot vol. 69 , ( 1 ) 68 - 74 .
Sosabowski J, Finucane C, Foster J, Ellison D, Burnet J, Mather S ( 2010 ) . Comparison Of 111-In Labelled CCK2-Receptor Targeting Peptides Using Nanospect/CT Imaging, A Collaborative Project Under COST BM0607 . EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING . vol. 37 , S268 - S268 .
Naqvi SAR, Matzow T, Finucane C, Nagra SA, Ishfaq MM, Mather SJ, Sosabowski J ( 2010 ) . Insertion of a lysosomal enzyme cleavage site into the sequence of a radiolabeled neuropeptide influences cell trafficking in vitro and in vivo . Cancer Biother Radiopharm vol. 25 , ( 1 ) 89 - 95 .
Sosabowski JK, Matzow T, Foster JM, Finucane C, Ellison D, Watson SA, Mather SJ ( 2009 ) . Targeting of CCK-2 receptor-expressing tumors using a radiolabeled divalent gastrin peptide . J Nucl Med vol. 50 , ( 12 ) 2082 - 2089 .
Sosabowski J, Matzow T, Foster J, Mather S ( 2009 ) . TARGETING OF CCK2 RECEPTOR EXPRESSING TUMOURS USING AN 111IN-LABELLED MINIGASTRIN DIMER . J LABELLED COMPD RAD vol. 52 , S327 - S327 .
Sosabowski JK, Lee M, Dekker BA, Simmons BP, Singh S, Beresford H, Hagan SA, McKenzie AJ et al. ( 2007 ) . Formulation development and manufacturing of a gastrin/CCK-2 receptor targeting peptide as an intermediate drug product for a clinical imaging study . Eur J Pharm Sci vol. 31 , ( 2 ) 102 - 111 .
Mather SJ, McKenzie AJ, Sosabowski JK, Morris TM, Ellison D, Watson SA ( 2007 ) . Selection of radiolabeled gastrin analogs for peptide receptor-targeted radionuclide therapy . J Nucl Med vol. 48 , ( 4 ) 615 - 622 .
Sosabowski JK, Mather SJ ( 2006 ) . Conjugation of DOTA-like chelating agents to peptides and radiolabeling with trivalent metallic isotopes . Nat Protoc vol. 1 , ( 2 ) 972 - 976 .
Sosabowski J, Mather SJ ( 2005 ) . Radiopharmacy - Overcoming the training barriers . Hospital Pharmacist vol. 12 , ( 8 ) 311 - 313 .
Whelan AN, Elaridi J, Smith SV, Mulder RJ, Robinson AJ, Sosabowski J ( 2005 ) . SYNTHESIS OF DICARBA ANALOGUES OF OCTREOTIDE USING TANDEM HOMOGENEOUS CATALYSIS . J LABELLED COMPD RAD vol. 48 , S238 - S238 .
Sosabowski J, Melendez-Alafort L, Mather S ( 2003 ) . Radiolabelling of peptides for diagnosis and therapy of non-oncological diseases . Q J NUCL MED vol. 47 , ( 4 ) 223 - 237 .
Fowkes RC, Sidhu KK, Sosabowski JK, King P, Burrin JM ( 2003 ) . Absence of pituitary adenylate cyclase-activating polypeptide-stimulated transcription of the human glycoprotein alpha-subunit gene in LbetaT2 gonadotrophs reveals disrupted cAMP-mediated gene transcription . J Mol Endocrinol vol. 31 , ( 2 ) 263 - 278 .
Lewis JS, Dearling JLJ, Sosabowski JK, Zweit J, Carnochan P, Kelland LR, Coley HM, Blower PJ ( 2000 ) . Copper bis(diphosphine) complexes: Radiopharmaceuticals for the detection of multi-drug resistance in tumours by PET . European Journal of Nuclear Medicine vol. 27 , ( 6 ) 638 - 646 .
Decristoforo C, Melendez-Alafort L, Sosabowski JK, Mather SJ ( 2000 ) . <sup>99m</sup>Tc-HYNIC-[Tyr<sup>3</sup>]-octreotide for imaging somatostatin-receptor- positive tumors: Preclinical evaluation and comparison with <sup>111</sup>In- octreotide . Journal of Nuclear Medicine vol. 41 , ( 6 ) 1114 - 1119 .
Brooks RC, Carnochan P, Vollano JF, Powell NA, Zweit J, Sosabowski JK, Martellucci S, Darkes MC et al. ( 1999 ) . Metal complexes of bleomycin: Evaluation of [Rh-105]-bleomycin for use in targeted radiotherapy . Nuclear Medicine and Biology vol. 26 , ( 4 ) 421 - 430 .