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Research

Publications: Prof Ahuva Nissim

Gigout A, Harazin D, Topping LM, Merciris D, Lindemann S, Brenneis C, Nissim A ( 2021 ) . Early detection of osteoarthritis in the rat with an antibody specific to type II collagen modified by reactive oxygen species . Arthritis Research and Therapy vol. 23 , ( 1 )
Vinci C, Infantino M, Raturi S, Tindell A, Topping LM, Strollo R, Amital H, Shoenfeld Y et al. ( 2020 ) . Immunoglobulin A antibodies to oxidized collagen type II as a potential biomarker for the stratification of spondyloarthritis from rheumatoid arthritis . Scandinavian Journal of Rheumatology vol. 49 , ( 4 ) 281 - 291 .
Topping LM, Thomas BL, Rhys HI, Tremoleda JL, Foster M, Seed M, Voisin MB, Vinci C et al. ( 2020 ) . Targeting Extracellular Vesicles to the Arthritic Joint Using a Damaged Cartilage-Specific Antibody . Frontiers in Immunology vol. 11 ,
Strollo R, Vinci C, Napoli N, Fioriti E, Maddaloni E, Åkerman L, Casas R, Pozzilli P et al. ( 2019 ) . Antibodies to oxidized insulin improve prediction of type 1 diabetes in children with positive standard islet autoantibodies . Diabetes/Metabolism Research and Reviews vol. 35 , ( 4 )
Nissim A ( 2019 ) . TARGETING COMBINED TREATMENT TO ARTHRITIC JOINTS BY ANTIBODY SPECIFIC TO DAMAGED CARTILAGE . RHEUMATOLOGY . vol. 58 ,
Strollo R, Vinci C, Napoli N, Fioriti E, Maddaloni E, Akerman L, Casas R, Pozzilli P et al. ( 2018 ) . Antibodies to oxidised insulin improve prediction of type 1 diabetes in children with positive standard islet-autoantibodies . DIABETOLOGIA . vol. 61 , S105 - S106 .
Smallwood MJ, Nissim A, Knight AR, Whiteman M, Haigh R, Winyard PG ( 2018 ) . Oxidative stress in autoimmune rheumatic diseases . Free Radical Biology and Medicine vol. 125 , 3 - 14 .
Strollo R, Vinci C, Napoli N, Pozzilli P, Ludvigsson J, Nissim A ( 2017 ) . Antibodies to post-translationally modified insulin as a novel biomarker for prediction of type 1 diabetes in children . Diabetologia vol. 60 , ( 8 ) 1467 - 1474 .
Strollo R, Vinci C, Napoli N, Pozzilli P, Ludvigsson J, Nissim A ( 2017 ) . Antibodies to Posttranslationally Modified Insulin for Prediction of Type 1 Diabetes in Children . DIABETES . vol. 66 , A58 - A58 .
Nissim A, Hughes C, Faurholm B, Lim NH, Vinchi C, Topping LM ( 2017 ) . 06.09 Targeting therapeutic and regenerative biomedicine specifically to arthritic joints . Annals of the Rheumatic Diseases . vol. 76 ,
Rizzo P, Pitocco D, Zaccardi F, Di Stasio E, Strollo R, Rizzi A, Scavone G, Costantini F et al. ( 2017 ) . Autoantibodies to post-translationally modified type I and II collagen in Charcot neuroarthropathy in subjects with type 2 diabetes mellitus . Diabetes/Metabolism Research and Reviews vol. 33 , ( 2 )
Hughes C, Nissim A ( 2016 ) . Progress and clinical potential of antibody-targeted therapy for arthritic damage . Expert Review of Proteomics vol. 13 , ( 6 ) 539 - 543 .
Lim NH, Vincent TL, Nissim A ( 2016 ) . Detection of early osteoarthritis by in vivo optical imaging of an antibody specific to type II collagen damaged by reactive oxidants . Osteoarthritis and Cartilage . vol. 24 ,
Lim NH, Vincent TL, Nissim A ( 2015 ) . In vivo optical imaging of early osteoarthritis using an antibody specific to damaged arthritic cartilage . Arthritis Research and Therapy vol. 17 , ( 1 )
Strollo R, Vinci C, Arshad MH, Perrett D, Tiberti C, Chiarelli F, Napoli N, Pozzilli P et al. ( 2015 ) . Antibodies to post-translationally modified insulin in type 1 diabetes . Diabetologia vol. 58 , ( 12 ) 2851 - 2860 .
Strollo R, Vinci C, Arshad MH, Perrett D, Tiberti C, Chiarelli F, Napoli N, Pozzilli P et al. ( 2015 ) . Autoantibodies to posttranslationally modified insulin in type 1 diabetes . DIABETOLOGIA . vol. 58 , S102 - S103 .
Maggiore C, Giovannoni G, Martin JE, Nissim A ( 2015 ) . Combinatorial antibody phage display libraries constructed from B-cells infiltrating brain tissue of people with progressive multiple sclerosis . MULTIPLE SCLEROSIS JOURNAL . vol. 21 , 464 - 465 .
Cohen-Saidon C, Nechushtan H, Kahlon S, Livni N, Nissim A, Razin E ( 2015 ) . Errata: A novel strategy using single-chain antibody to show the importance of Bcl-2 in mast cell survival (Blood (2003) 102, 7 (2506-2512)) . Blood vol. 125 , ( 15 )
Kuhle J, Gaiottino J, Leppert D, Petzold A, Bestwick JP, Malaspina A, Lu CH, Dobson R et al. ( 2015 ) . Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome . Journal of Neurology, Neurosurgery and Psychiatry vol. 86 , ( 3 ) 273 - 279 .
Kuhle J, Gaiottino J, Leppert D, Petzold A, Bestwick JP, Malaspina A, Lu C-H, Dobson R et al. ( 2015 ) . Serum neurofilament light chain is a biomarker of human spinal cord injury severity and outcome . J Neurol Neurosurg Psychiatry vol. 86 , ( 3 ) 273 - 279 .
Hughes C, Sette A, Seed M, D'Acquisto F, Manzo A, Vincent TL, Lim NH, Nissim A ( 2014 ) . Targeting of viral interleukin-10 with an antibody fragment specific to damaged arthritic cartilage improves its therapeutic potency . Arthritis Res Ther vol. 16 , ( 4 )
Burska AN, Hunt L, Boissinot M, Strollo R, Ryan BJ, Vital E, Nissim A, Winyard PG et al. ( 2014 ) . Autoantibodies to Posttranslational Modifications in Rheumatoid Arthritis . MEDIATORS OF INFLAMMATION vol. 2014 , Article ARTN 492873 ,
Ryan BJ, Nissim A, Winyard PG ( 2014 ) . Oxidative post-translational modifications and their involvement in the pathogenesis of autoimmune diseases . Redox Biol vol. 2 , 715 - 724 .
Kuhle J, Plattner K, Bestwick JP, Lindberg RL, Ramagopalan SV, Norgren N, Nissim A, Malaspina A et al. ( 2013 ) . A comparative study of CSF neurofilament light and heavy chain protein in MS . Mult Scler vol. 19 , ( 12 ) 1597 - 1603 .
Strollo R, Ponchel F, Malmström V, Rizzo P, Bombardieri M, Wenham CY, Landy R, Perret D et al. ( 2013 ) . Autoantibodies to posttranslationally modified type II collagen as potential biomarkers for rheumatoid arthritis . Arthritis Rheum vol. 65 , ( 7 ) 1702 - 1712 .
Rizzo P, Pitocco D, Scavone G, Di Stasio E, Costantini F, Strollo R, Galli M, Pozzilli P et al. ( 2013 ) . The Role of Collagen Neoepitopes Generated by Oxidative Stress in the Pathogenesis of Charcot Neuroarthropathy . DIABETES . vol. 62 , A619 - A619 .
Maggiore C, Giovannoni G, Martin J, Nissim A ( 2013 ) . Construction of an antibody phage display library from B-cells infiltrating brain tissue of people with progressive multiple sclerosis . JOURNAL OF NEUROLOGY vol. 260 , S39 - S39 .
Eggleton P, Nissim A, Ryan BJ, Whiteman M, Winyard PG ( 2013 ) . Detection and isolation of human serum autoantibodies that recognize oxidatively modified autoantigens . Free Radic Biol Med vol. 57 , 79 - 91 .
Strollo R, Rizzo P, Spoletini M, Landy R, Hughes C, Ponchel F, Napoli N, Palermo A et al. ( 2013 ) . HLA-dependent autoantibodies against post-translationally modified collagen type II in type 1 diabetes mellitus . Diabetologia vol. 56 , ( 3 ) 563 - 572 .
Gaiottino J, Norgren N, Dobson R, Topping J, Nissim A, Malaspina A, Bestwick JP, Monsch AU et al. ( 2013 ) . Increased neurofilament light chain blood levels in neurodegenerative neurological diseases . PLoS One vol. 8 , ( 9 )
Man YKS, DiCara D, Chan N, Vessillier S, Mather SJ, Rowe ML, Howard MJ, Marshall JF et al. ( 2013 ) . Structural guided scaffold phage display libraries as a source of bio-therapeutics . PLoS One vol. 8 , ( 8 )
Wythe SE, DiCara D, Taher TEI, Finucane CM, Jones R, Bombardieri M, Man YKS, Nissim A et al. ( 2013 ) . Targeted delivery of cytokine therapy to rheumatoid tissue by a synovial targeting peptide . Ann Rheum Dis vol. 72 , ( 1 ) 129 - 135 .
Winyard⁎ PG, Nissim A, Ryan B, Whiteman M, Eggleton P ( 2012 ) . Measurement of serum autoantibodies against oxidatively modified autoantigens in human autoimmune diseases . Free Radical Biology and Medicine vol. 53 , s64 - s65 .
Harel D, Marron A, Nissim A, Weiss G ( 2012 ) . A Software Engineering Framework for Switched Fuzzy Systems . Conference: 2012 IEEE International Conference on Fuzzy Systems1 - 9 .
Hughes C, Faurholm B, Dell'Accio F, Manzo A, Seed M, Eltawil NM, Amarrelli A, Al-Kashi A et al. ( 2012 ) . TARGETING THERAPEUTICS TO ARTHRITIC JOINTS BY ANTIBODY SPECIFIC TO POST-TRANSLATIONALLY MODIFIED COLLAGEN TYPE II . ANNALS OF THE RHEUMATIC DISEASES . vol. 71 ,
Kamperidis P, Kamalati T, Ferrari M, Jones M, Garrood T, Smith MD, Diez-Posada S, Hughes C et al. ( 2011 ) . Development of a novel recombinant biotherapeutic with applications in targeted therapy of human arthritis . Arthritis Rheum vol. 63 , ( 12 ) 3758 - 3767 .
Hughes C, Faurholm B, Dell'Accio F, Manzo A, Seed M, Al-Kashi A, Winyard P, Chernajovsky Y et al. ( 2011 ) . Targeting therapeutics to arthritic joints . IMMUNOLOGY . vol. 135 , 189 - 189 .
Kamperidis P, Kamalati T, Ferrari M, Lee L, Jones R, Garrood T, Smith MD, Diez-Posada S et al. ( 2011 ) . Development of a Novel Recombinant Biotherapeutic with Applications in Targeted Therapy of Human Arthritis . ARTHRITIS AND RHEUMATISM . vol. 63 , S499 - S499 .
Winyard PG, Ryan B, Eggleton P, Nissim A, Taylor E, Lo Faro ML, Burkholz T, Szabó-Taylor KE et al. ( 2011 ) . Measurement and meaning of markers of reactive species of oxygen, nitrogen and sulfur in healthy human subjects and patients with inflammatory joint disease . Biochem Soc Trans vol. 39 , ( 5 ) 1226 - 1232 .
Hughes C, Faurholm B, Dell'Accio F, Manzo A, Seed M, Eltawil N, Marrelli A, Gould D et al. ( 2011 ) . TARGETING THERAPEUTICS TO ARTHRITIC JOINTS . RHEUMATOLOGY . vol. 50 , 127 - 127 .
Anger J, Rogo-Gupta L, Behniwal A, Rashid R, Nissim A, Le T, Smith A, Litwin M et al. ( 2011 ) . IS "OAB-DRY" REALLY DRY? . NEUROUROLOGY AND URODYNAMICS . vol. 30 , 261 - 262 .
Eggleton P, Ryan B, Brown S, Johnson S, Viner N, Nissim A, Isenberg D, Haigh R et al. ( 2011 ) . POST-TRANSLATIONAL MODIFICATIONS OF C1Q LEAD TO ANTIGENICITY AND BREAKDOWN OF IMMUNE TOLERANCE IN SYSTEMIC LUPUS ERYTHEMATOSUS . CLIN EXP RHEUMATOL vol. 29 , ( 1 ) 176 - 176 .
Hendler A, Mulli TK, Hughes FJ, Perrett D, Bombardieri M, Houri-Haddad Y, Weiss EI, Nissim A ( 2010 ) . Involvement of autoimmunity in the pathogenesis of aggressive periodontitis . Journal of Dental Research vol. 89 , ( 12 ) 1389 - 1394 .
Nissim A, DiCara D ( 2010 ) . Methods for Development of Monoclonal Antibody Therapeutics . Targeted Radionuclide Therapy , Editors: Speer, TW , Lippincott Williams and Wilkins
Hughes C, Faurholm B, Dell'Accio F, Manzo A, Seed M, Eltawil N, Marrelli A, Gould D et al. ( 2010 ) . Human single-chain variable fragment that specifically targets arthritic cartilage . Arthritis Rheum vol. 62 , ( 4 ) 1007 - 1016 .
Wythe SE, DiCara D, Finucane C, Man S, Jones R, Nissim A, Mather SJ, Chernajovsky Y et al. ( 2010 ) . TARGETING THE INFLAMED MICROVASCULATURE IN RHEUMATOID ARTHRITIS . RHEUMATOLOGY . vol. 49 , I12 - I13 .
Ryan B, Eggleton P, Brown S, Viner N, Nissim A, Isenberg D, Haigh R, Winyard PG ( 2010 ) . Oxidative and Nitrative Modification of C1q Affects its Structure, Function and Antigenicity in Systemic Lupus Erythematosus . FREE RADICAL BIOLOGY AND MEDICINE . vol. 49 , S148 - S148 .
Ryan B, Winyard PG, Viner N, Haigh R, Haas M, Nissim A, Isenberg D, Eggleton P ( 2009 ) . OXIDATIVE MODIFICATIONS TO C1Q INCREASE THE SENSITIVITY OF AN ANTI-C1Q ELISA IN THE DIAGNOSIS OF SYSTEMIC LUPUS ERYTHEMATOSUS . RHEUMATOLOGY . vol. 48 , I2 - I2 .
Maggiore C, Meier UC, Marta M, Nissim A, Giovannoni G ( 2009 ) . B Cells and EBV Infection in People with MS . NEUROLOGY . vol. 72 , A37 - A37 .
Nissim A, Chernajovsky Y ( 2008 ) . Preface .
Maggiore C, Trillo-Pazos G, Keir G, Pizzolato G, Edomi P, Nissim A, Giovannoni G ( 2008 ) . Ectopic germinal centres in the brain of people with multiple sclerosis . MULTIPLE SCLEROSIS . vol. 14 , S231 - S231 .
Nissim A, Chernajovsky Y ( 2008 ) . Historical development of monoclonal antibody therapeutics .
Nissim A ( 2008 ) . NOVEL ANTIBODY AND USE IN DIAGNOSIS AND THERAPY OF ARTHROPATHIES .
Ryan B, Szestakowska D, Viner N, Haigh R, Haas M, Nissim A, Isenberg D, Winyard P et al. ( 2007 ) . Autoantibodies target oxidatively modified proteins of the C1q/calreticulin/CD91 apoptotic pathway in systemic lupus erythematosus . ANNALS OF THE RHEUMATIC DISEASES . vol. 66 , 315 - 315 .
Brunton F, Lee L, Nissim A, Grigoriadis AE, Pitzalis C ( 2007 ) . Targeting osteoclasts in rheumatoid arthritis via the alpha(v)beta(3) integrin . JOURNAL OF BONE AND MINERAL RESEARCH . vol. 22 , 1113 - 1113 .
Kamperidis PS, Lee L, Blades M, Garrood T, Nissim A, George A, Pitzalis C ( 2007 ) . Identification of single-chain antibody fragments specific for human synovial microvascular endothelium by in vivo phage display . ANNALS OF THE RHEUMATIC DISEASES . vol. 66 , A12 - A13 .
Brunton F, Lee L, Nissim A, Grigoriadis A, Pitzalis C ( 2007 ) . Modulating osteoclast function by targeting the alphavbeta3 integrin . ANNALS OF THE RHEUMATIC DISEASES . vol. 66 , A19 - A19 .
Nissim A, Chernajovsky Y ( 2007 ) . Therapeutic Antibodies . Editors: Nissim, A, Chernajovsky, Y , Springer ( Berlin ),
Eggleton P, Szestakowska D, Winyard PG, Viner N, Nissim A ( 2006 ) . Generation of neo-antigenic epitopes recognised by autoimmune sera after the post-translational modification of human C1q by free radicals . RHEUMATOLOGY . vol. 45 , I103 - I103 .
Winyard PG, Nissim A, Davies C, Rocks S, Benjamin N ( 2006 ) . Nitrosative stress in the inflamed joints of rheumatoid arthritis patients . FREE RADICAL RESEARCH . vol. 40 , S111 - S111 .
Szestakowska D, Young P, Morse R, Viner N, Isenberg D, Nissim A, Eggleton P, Winyard P ( 2006 ) . Role of oxidative protein modifications in the generation of neoantigens recognised by lupus patient sera . FREE RADICAL RESEARCH . vol. 40 , S115 - S115 .
Nissim A, Winyard PG, Corrigall V, Fatah R, Perrett D, Panayi G, Chernajovsky Y ( 2005 ) . Generation of neoantigenic epitopes after posttranslational modification of type II collagen by factors present within the inflamed joint . Arthritis Rheum vol. 52 , ( 12 ) 3829 - 3838 .
Yudkoff M, Daikhin Y, Nissim A, Horyn O, Luhovyy B, Lazarow A, Nissim I ( 2005 ) . Brain amino acid requirements and toxicity: The example of leucine (vol 135, pg 1531S, 2005) . J NUTR vol. 135 , ( 8 ) 2009 - 2009 .
Horyn O, Luhovyy B, Lazarow A, Daikhin Y, Nissim A, Yudkoff M, Nissim I ( 2005 ) . Biosynthesis of agmatine in isolated mitochondria and perfused rat liver: studies with N-15-labelled arginine . BIOCHEM J vol. 388 , 419 - 425 .
Nissim A, Winyard P, Davis C, Cohen G, Chernajovsky Y ( 2005 ) . Development of human antibody fragments against collagen type II autoantigens in rheumatoid arthritis, using phage display libraries . RHEUMATOLOGY . vol. 44 , I43 - I44 .
Inglis JJ, Nissim A, Lees DM, Hunt SP, Chernajovsky Y, Kidd BL ( 2005 ) . The differential contribution of tumour necrosis factor to thermal and mechanical hyperalgesia during chronic inflammation . Arthritis Res Ther vol. 7 , ( 4 ) R807 - R816 .
Nissim A, Winyard P, Fatah R, Perrett D, Chernajovsky Y, Panayi G, Corrigall V ( 2004 ) . Generation of neo-antigenic epitopes after the post-translational modification of type II collagen by factors present within the inflamed joint . ARTHRITIS AND RHEUMATISM . vol. 50 , S223 - S223 .
Nissim A, Gofur Y, Vessillier S, Adams G, Chernajovsky Y ( 2004 ) . Methods for targeting biologicals to specific disease sites . Trends Mol Med vol. 10 , ( 6 ) 269 - 274 .
NISSIM A, Nechushtan H, Cohen-Saidon C, Razin E, Kahlon S, Livni N ( 2003 ) . A novel strategy using single chain antibody to show the importance of Bcl-2 in mast cell survival . Blood vol. 102 , ( 7 ) 2506 - 2512 .
NISSIM A, Loyter A, Piller SC, Graessmann A, Krichevsky A, Zakai N ( 2003 ) . Antibody Fragments Selected by Phage Display Against the Nuclear Localization Signal of the HIV-1 Vpr Protein Inhibit Nuclear Import in Permeabilized and Intact Cultured Cells . Virology vol. 305 , ( 1 ) 77 - 92 .
Gargir A, Ofek I, Meron-Sudai S, Tanamy MG, Kabouridis PS, Nissim A ( 2002 ) . Single chain antibodies specific for fatty acids derived from a semi-synthetic phage display library . BBA-GEN SUBJECTS vol. 1569 , ( 1-3 ) 167 - 173 .
Flores-Flores C, Nissim A, Shochat S, Soreq H ( 2002 ) . Development of human antibody fragments directed towards synaptic acetylcholinesterase using a semi-synthetic phage display library . AGEING AND DEMENTIA CURRENT AND FUTURE CONCEPTS . Editors: Jellinger, KA, Schmidt, R, Windisch, M , 165 - 179 .
NISSIM A, Soreq H, Flores-Flores C, Shochat S ( 2002 ) . Phage display selection and characterization of myc-tagged humanized monoclonal antibodies to synaptic acetylcholinesterase . J Neural Transm. vol. 62 , ( Suppl ) 163 - 177 .
Gargir A, Ofek I, Hasty D, Meron-Sudai S, Tsubery H, Keisari Y, Nissim A ( 2001 ) . Inhibition of anti body-dependent stimulation of lipoteichoic acid-treated human monocytes and macrophages by polyglycerolphosphate-reactive peptides . J LEUKOCYTE BIOL vol. 70 , ( 4 ) 537 - 542 .
Kjaer S, Wind T, Ravn P, Ostergaard M, Clark BFC, Nissim A ( 2001 ) . Generation and epitope mapping of high-affinity scFv to eukaryotic elongation factor 1A by dual application of phage display . EUR J BIOCHEM vol. 268 , ( 12 ) 3407 - 3415 .
Vaisman N, Nissim A, Klapper LN, Tirosh B, Yarden Y, Sela M ( 2000 ) . Specific inhibition of the reaction between a tumor-inhibitory antibody and the ErbB-2 receptor by a mimotope derived from a phage display library . Immunol Lett vol. 75 , ( 1 ) 61 - 67 .
Uchanska-Ziegler B, Qiao X, Volz A, Nissim A, Ziegler A ( 2000 ) . Human single-chain Fv fragments specific for natural killer cell receptors from phage display libraries . Methods Mol Biol vol. 121 , 219 - 237 .
Neri D, Pini A, Nissim A ( 1998 ) . Antibodies from phage display libraries as immunochemical reagents . Methods Mol Biol vol. 80 , 475 - 500 .
Neri D, Carnemolla B, Nissim A, Leprini A, Querze G, Balza E, Pini A, Tarli L et al. ( 1997 ) . Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform . NATURE BIOTECHNOLOGY vol. 15 , ( 11 ) 1271 - 1275 .
Neri D, Carnemolla B, Nissim A, Leprini A, Querzè G, Balza E, Pini A, Tarli L et al. ( 1997 ) . Targeting by affinity-matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform . Nat Biotechnol vol. 15 , ( 12 ) 1271 - 1275 .
Oren-Shamir M, Levi-Nissim A ( 1997 ) . UV-light effect on the leaf pigmentation of Cotinus coggygria 'Royal Purple' . SCIENTIA HORTICULTURAE vol. 71 , ( 1-2 ) 59 - 66 .
Evenor D, Levi-Nissim A, Afgin L, Lilien-Kipnis H, Watad AA ( 1997 ) . Regeneration of plantlets and bulblets from explants and callus of Allium aflatunense cultivars and selection from indigenous Israeli Allium ampeloprasum . FLOWER BULBS - SEVENTH INTERNATIONAL SYMPOSIUM, VOLS 1 AND 2 . 325 - 330 .
Nissim A, Neri D, Winter G ( 1996 ) . Development and usage of semi-synthetic scFv repertoires displayed on phage . Human Antibodies and Hybridomas vol. 7 , ( 2 )
Harrison JL, Williams SC, Winter G, Nissim A ( 1996 ) . Screening of phage antibody libraries . Methods Enzymol vol. 267 , 83 - 109 .
Nissim A, Schwarzbaum S, Eshhar Z ( 1995 ) . The use of mouse/human IgE chimeras to map the FcϵR Binding Site of IgE . Methods vol. 8 , ( 2 ) 124 - 132 .
GRIFFITHS AD, WILLIAMS SC, HARTLEY O, TOMLINSON IM, WATERHOUSE P, CROSBY WL, KONTERMANN RE, JONES PT et al. ( 1994 ) . ISOLATION OF HIGH-AFFINITY HUMAN-ANTIBODIES DIRECTLY FROM LARGE SYNTHETIC REPERTOIRES . EMBO J vol. 13 , ( 14 ) 3245 - 3260 .
Nissim A, Hoogenboom HR, Tomlinson IM, Flynn G, Midgley C, Lane D, Winter G ( 1994 ) . Antibody fragments from a 'single pot' phage display library as immunochemical reagents . EMBO J vol. 13 , ( 3 ) 692 - 698 .
NISSIM A, HOOGENBOOM HR, TOMLINSON IM, FLYNN G, MIDGLEY C, LANE D, WINTER G ( 1994 ) . ANTIBODY FRAGMENTS FROM A SINGLE POT PHAGE DISPLAY LIBRARY AS IMMUNOCHEMICAL REAGENTS . J CELL BIOCHEM203 - 203 .
Nissim A, Schwarzbaum S, Siraganian R, Eshhar Z ( 1993 ) . Fine specificity of the IgE interaction with the low and high affinity Fc receptor . J Immunol vol. 150 , ( 4 ) 1365 - 1374 .
Nissim A, Eshhar Z ( 1992 ) . The human mast cell receptor binding site maps to the third constant domain of immunoglobulin E . Mol Immunol vol. 29 , ( 9 ) 1065 - 1072 .
Rutherford MN, Kumar A, Nissim A, Chebath J, Williams BR ( 1991 ) . The murine 2-5A synthetase locus: three distinct transcripts from two linked genes . Nucleic Acids Res vol. 19 , ( 8 ) 1917 - 1924 .
NISSIM A, ESHHAR Z ( 1991 ) . THE MAST-CELL BINDING-SITE MAPPS TO THE 3RD CONSTANT REGION DOMAIN OF IMMUNOGLOBULIN-E . FASEB J vol. 5 , ( 5 ) A1086 - A1086 .
Nissim A, Eshhar Z ( 1991 ) . Localization of the Fc epsilon RI binding site to the third constant domain of IgE . Int Arch Allergy Appl Immunol vol. 94 , ( 1-4 ) 93 - 95 .
Nissim A, Jouvin MH, Eshhar Z ( 1991 ) . Mapping of the high affinity Fc epsilon receptor binding site to the third constant region domain of IgE . EMBO J vol. 10 , ( 1 ) 101 - 107 .
Coccia EM, Romeo G, Nissim A, Marziali G, Albertini R, Affabris E, Battistini A, Fiorucci G et al. ( 1990 ) . A full-length murine 2-5A synthetase cDNA transfected in NIH-3T3 cells impairs EMCV but not VSV replication . Virology vol. 179 , ( 1 ) 228 - 233 .
Schwarzbaum S, Nissim A, Alkalay I, Ghozi MC, Schindler DG, Bergman Y, Eshhar Z ( 1989 ) . Mapping of murine IgE epitopes involved in IgE-Fc epsilon receptor interactions . Eur J Immunol vol. 19 , ( 6 ) 1015 - 1023 .
David S, Nissim A, Chebath J, Salzberg S ( 1989 ) . 2'-5'-oligoadenylate synthetase gene expression in normal and murine sarcoma virus-transformed NIH 3T3 cells . J Virol vol. 63 , ( 3 ) 1116 - 1122 .
CHITAYAT SD, NISSIM A, COCCIA C, CHEBATH J, SALZBERG S ( 1987 ) . 2-5A SYNTHETASE GENE-EXPRESSION IN NORMAL AND MSV-TRANSFORMED NIH/3T3 CELLS . JOURNAL OF INTERFERON RESEARCH . vol. 7 , 730 - 730 .
NISSIM A, COCCIA E, COHEN B, BENECH P, CHEBATH J ( 1987 ) . 3 DIFFERENT 2'-5'OLIGO A SYNTHETASE GENES ARE ACTIVE IN MOUSE CELLS AND MULTIPLE FORMS OF ENZYMES ARE INDUCED BY INTERFERONS . J INTERFERON RES vol. 7 , ( 6 ) 728 - 728 .