Publications: Prof Yongjie Lu

Chang Q, Chen P, Yin J, Liang G, Dai Y, Guan Y, Chen Y, Zhao Y et al. ( 2023 ) . Discovery and validation of bladder cancer related excreted nucleosides biomarkers by dilution approach in cell culture supernatant and urine using UHPLC-MS/MS . Journal of Proteomics vol. 270 ,

Zhang Y, Wang K, Yang D, Liu F, Xu X, Feng Y, Wang Y, Zhu S et al. ( 2022 ) . Hsa_circ_0094606 promotes malignant progression of prostate cancer by inducing M2 polarization of macrophages through PRMT1-mediated arginine methylation of ILF3 . Carcinogenesis

Burns D, Anokian E, Saunders EJ, Bristow RG, Fraser M, Reimand J, Schlomm T, Sauter G et al. ( 2022 ) . Rare Germline Variants Are Associated with Rapid Biochemical Recurrence After Radical Prostate Cancer Treatment: A Pan Prostate Cancer Group Study . European Urology vol. 82 , ( 2 ) 201 - 211 .

Huynh-Le MP, Karunamuni R, Fan CC, Asona L, Thompson WK, Martinez ME, Eeles RA, Kote-Jarai Z et al. ( 2022 ) . Prostate cancer risk stratification improvement across multiple ancestries with new polygenic hazard score . Prostate cancer and prostatic diseases vol. 25 , ( 4 ) 755 - 761 .

Morales Berstein F, McCartney DL, Lu AT, Tsilidis KK, Bouras E, Haycock P, Burrows K, Phipps AI et al. ( 2022 ) . Assessing the causal role of epigenetic clocks in the development of multiple cancers: a Mendelian randomization study . Elife vol. 11 ,

Zhang Y, Hollis D, Ross R, Snow T, Terrill NJ, Lu Y, Wang W, Connelly J et al. ( 2022 ) . Investigating the Fibrillar Ultrastructure and Mechanics in Keloid Scars Using In Situ Synchrotron X-ray Nanomechanical Imaging . Materials (Basel) vol. 15 , ( 5 )

Xue X, Dong L, Burke E, Xue L, Lu Y-J ( 2022 ) . The interaction of p53 and DNA repair gene mutations and their impact on tumor mutation burden and immune response in human malignancies . Am J Cancer Res vol. 12 , ( 4 ) 1866 - 1883 .

Huynh-Le MP, Fan CC, Karunamuni R, Thompson WK, Martinez ME, Eeles RA, Kote-Jarai Z, Muir K et al. ( 2021 ) . Polygenic hazard score is associated with prostate cancer in multi-ethnic populations . Nature Communications vol. 12 , ( 1 )

Martin K, Zhang T, Lin TT, Habowski AN, Zhao R, Tsai CF, Chrisler WB, Sontag RL et al. ( 2021 ) . Facile One-Pot Nanoproteomics for Label-Free Proteome Profiling of 50-1000 Mammalian Cells . Journal of Proteome Research vol. 20 , ( 9 ) 4452 - 4461 .

Guo Y, Yin J, Dai Y, Guan Y, Chen P, Chen Y, Huang C, Lu YJ et al. ( 2021 ) . A Novel CpG Methylation Risk Indicator for Predicting Prognosis in Bladder Cancer . Frontiers in Cell and Developmental Biology vol. 9 ,

Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA et al. ( 2021 ) . Publisher Correction: Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction (Nature Genetics, (2021), 53, 1, (65-75), 10.1038/s41588-020-00748-0) . Nature Genetics vol. 53 , ( 3 )

Guo T, Wang Y, Jia J, Mao X, Stankiewicz E, Scandura G, Burke E, Xu L et al. ( 2021 ) . The Identification of Plasma Exosomal miR-423-3p as a Potential Predictive Biomarker for Prostate Cancer Castration-Resistance Development by Plasma Exosomal miRNA Sequencing . Frontiers in Cell and Developmental Biology vol. 8 ,

Marzec J, Ross-Adams H, Pirrò S, Wang J, Zhu Y, Mao X, Gadaleta E, Ahmad AS et al. ( 2021 ) . The transcriptomic landscape of prostate cancer development and progression: An integrative analysis . Cancers vol. 13 , ( 2 ) 1 - 24 .

Conti DV, Darst BF, Moss LC, Saunders EJ, Sheng X, Chou A, Schumacher FR, Olama AAA et al. ( 2021 ) . Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction . Nature Genetics vol. 53 , ( 1 ) 65 - 75 .

Wu L, Yang Y, Guo X, Shu XO, Cai Q, Shu X, Li B, Tao R et al. ( 2020 ) . An integrative multi-omics analysis to identify candidate DNA methylation biomarkers related to prostate cancer risk . Nature Communications vol. 11 , ( 1 )

Bailey MH, Meyerson WU, Dursi LJ, Wang LB, Dong G, Liang WW, Weerasinghe A, Li S et al. ( 2020 ) . Author Correction: Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples (Nature Communications, (2020), 11, 1, (4748), 10.1038/s41467-020-18151-y) . Nature Communications vol. 11 , ( 1 )

Hollis B, Day FR, Busch AS, Thompson DJ, Soares ALG, Timmers PRHJ, Kwong A, Easton DF et al. ( 2020 ) . Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan . Nature Communications vol. 11 , ( 1 )

Bailey MH, Meyerson WU, Dursi LJ, Wang LB, Dong G, Liang WW, Weerasinghe A, Li S et al. ( 2020 ) . Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples . Nature Communications vol. 11 , ( 1 )

Li CH, Prokopec SD, Sun RX, Yousif F, Schmitz N, Al-Shahrour F, Atwal G, Bailey PJ et al. ( 2020 ) . Sex differences in oncogenic mutational processes . Nature Communications vol. 11 , ( 1 )

Campbell PJ, Getz G, Korbel JO, Stuart JM, Jennings JL, Stein LD, Perry MD, Nahal-Bose HK et al. ( 2020 ) . Pan-cancer analysis of whole genomes . Nature vol. 578 , ( 7793 ) 82 - 93 .

Xu L, Mao X, Grey A, Scandura G, Guo T, Burke E, Marzec J, Abdu S et al. ( 2020 ) . Reply by Authors . The Journal of urology vol. 203 , ( 1 ) 81 - 82 .

Law PJ, Timofeeva M, Fernandez-Rozadilla C, Broderick P, Studd J, Fernandez-Tajes J, Farrington S, Svinti V et al. ( 2019 ) . Association analyses identify 31 new risk loci for colorectal cancer susceptibility . Nature Communications vol. 10 , ( 1 )

Matejcic M, Saunders EJ, Dadaev T, Brook MN, Wang K, Sheng X, Olama AAA, Schumacher FR et al. ( 2019 ) . Erratum to: Germline variation at 8q24 and prostate cancer risk in men of European ancestry (Nature Communications, (2018), 9, 1, (4616), 10.1038/s41467-018-06863-1) . Nature Communications vol. 10 , ( 1 )

Mancuso N, Gayther S, Gusev A, Zheng W, Penney KL, Henderson BE, Benlloch S, Schumacher FR et al. ( 2019 ) . Erratum to: Large-scale transcriptome-wide association study identifies new prostate cancer risk regions (Nature Communications, (2018), 9, 1, (4079), 10.1038/s41467-018-06302-1) . Nature Communications vol. 10 , ( 1 )

Song D, Powles T, Shi L, Zhang L, Ingersoll MA, Lu YJ ( 2019 ) . Bladder cancer, a unique model to understand cancer immunity and develop immunotherapy approaches . Journal of Pathology vol. 249 , ( 2 ) 151 - 165 .

Stankiewicz E, Guo T, Mao X, Lu YJ ( 2019 ) . Fluorescence in situ hybridization and rehybridization using bacterial artificial chromosome probes . Methods in Molecular Biology vol. 2054 , 243 - 261 .

Guo T, Stankiewicz E, Mao X, Lu YJ ( 2019 ) . The isolation and analysis of circulating tumor cells . Methods in Molecular Biology vol. 2054 , 115 - 128 .

Xu L, Mao X, Grey A, Scandura G, Guo T, Burke E, Marzec J, Abdu S et al. ( 2019 ) . Noninvasive Detection of Clinically Significant Prostate Cancer Using Circulating Tumor Cells . The Journal of Urology vol. 203 , 101097JU000000000000 - 101097JU000000000000 .

Guo T, Wang Y, Mao X, Xu L, Marzec J, Burke E, Scandura G, Stankiewicz E et al. ( 2019 ) . Abstract 2580: Investigation of plasma exosomal miRNA as a biomarker and its potential function in prostate cancer castration resistant development . Conference: Molecular and Cellular Biology / Genetics2580 - 2580 .

Wu L, Wang J, Cai Q, Cavazos TB, Emami NC, Long J, Shu X-O, Lu Y et al. ( 2019 ) . Identification of Novel Susceptibility Loci and Genes for Prostate Cancer Risk: A Transcriptome-Wide Association Study in Over 140,000 European Descendants . Cancer Res vol. 79 , ( 13 ) 3192 - 3204 .

Loveday C, Sud A, Litchfield K, Levy M, Holroyd A, Broderick P, Kote-Jarai Z, Dunning AM et al. ( 2019 ) . Runs of homozygosity and testicular cancer risk . Andrology vol. 7 , ( 4 ) 555 - 564 .

Yeste-Velasco M, Guo T, Mao X, Stankiewicz E, Scandura G, Li H, Wang CS, Kudahetti S et al. ( 2019 ) . The potential of brentuximab vedotin, alone or in combination with current clinical therapies, in the treatment of testicular germ cell tumors . American Journal of Cancer Research vol. 9 , ( 5 ) 855 - 871 .

Xue X, Shi F, Dong L, Rong L, Li L, Zheng B, Liu X, Liu W et al. ( 2019 ) . Predisposition of Adrenocortical Carcinoma by Loss of Function of Mismatch Repair Genes and The Role of TP53 In Cancer Development . LABORATORY INVESTIGATION . vol. 99 ,

Schumacher FR, Olama AAA, Berndt SI, Benlloch S, Ahmed M, Saunders EJ, Dadaev T, Leongamornlert D et al. ( 2019 ) . Correction to: Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci (Nature Genetics, (2018), 50, 7, (928-936), 10.1038/s41588-018-0142-8) . Nature Genetics vol. 51 , ( 2 )

Xu L, Bastus NC, Lu Y-J ( 2019 ) . Chapter 15 Sequencing a Single Circulating Tumor Cell for Genomic Assessment . Oncogenomics ,

Adams CD, Richmond R, Santos Ferreira DL, Spiller W, Tan V, Zheng J, Würtz P, Donovan J et al. ( 2019 ) . Circulating metabolic biomarkers of screen-detected prostate cancer in the ProtecT study . Cancer Epidemiology Biomarkers and Prevention vol. 28 , ( 1 ) 208 - 216 .

Lin HY, Huang PY, Chen DT, Tung HY, Sellers TA, Pow-Sang JM, Eeles R, Easton D et al. ( 2018 ) . AA9int: SNP interaction pattern search using non-hierarchical additive model set . Bioinformatics vol. 34 , ( 24 ) 4141 - 4150 .

Dadaev T, Saunders EJ, Newcombe PJ, Anokian E, Leongamornlert DA, Brook MN, Cieza-Borrella C, Mijuskovic M et al. ( 2018 ) . Fine-mapping of prostate cancer susceptibility loci in a large meta-analysis identifies candidate causal variants . Nature Communications vol. 9 , ( 1 )

Vijayakrishnan J, Studd J, Broderick P, Kinnersley B, Holroyd A, Law PJ, Kumar R, Allan JM et al. ( 2018 ) . Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia . Nature Communications vol. 9 , ( 1 )

Matejcic M, Saunders EJ, Dadaev T, Brook MN, Wang K, Sheng X, Olama AAA, Schumacher FR et al. ( 2018 ) . Germline variation at 8q24 and prostate cancer risk in men of European ancestry . Nature Communications vol. 9 , ( 1 )

Went M, Sud A, Försti A, Halvarsson BM, Weinhold N, Kimber S, van Duin M, Thorleifsson G et al. ( 2018 ) . Identification of multiple risk loci and regulatory mechanisms influencing susceptibility to multiple myeloma . Nature Communications vol. 9 , ( 1 )

Mancuso N, Gayther S, Gusev A, Zheng W, Penney KL, Kote-Jarai Z, Eeles R, Freedman M et al. ( 2018 ) . Large-scale transcriptome-wide association study identifies new prostate cancer risk regions . Nature Communications vol. 9 , ( 1 )

Guo T, Wang Y, Mao X, Xu L, Marzec J, Burke E, Shaw G, Hines J et al. ( 2018 ) . Investigation of exosomal miRNA as biomarker for prostate cancer castration resistance development . BRITISH JOURNAL OF CANCER . Conference: NCRI Cancer Conferences vol. 119 , 32 - 32 .

Adimonye A, Stankiewicz E, Touche SL, Kudahetti S, Tinwell B, Corbishley C, Lu Y-J, Watkin N et al. ( 2018 ) . The Prognostic Value of PIK3CA Copy Number Gain in Penile Cancer . Urology

Matejcic M, Saunders EJ, Dadaev T, Brook M, Olama AAA, Schumacher FR, Berndt SI, Benlloch S et al. ( 2018 ) . Abstract 227: Germline variation at 8q24 and prostate cancer risk in men of European ancestry . Cancer Research . vol. 78 , 227 - 227 .

Schumacher FR, Al Olama AA, Berndt SI, Benlloch S, Ahmed M, Saunders EJ, Dadaev T, Leongamornlert D et al. ( 2018 ) . Association analyses of more than 140,000 men identify 63 new prostate cancer susceptibility loci . Nature Genetics vol. 50 , ( 7 ) 928 - 936 .

Adimonye A, Stankiewicz E, La-Touche S, Kudahetti S, Trevisan G, Tinwell B, Corbishley C, Lu Y-J et al. ( 2018 ) . PIK3CA copy number aberration and activation of the PI3K-AKT-mTOR pathway in varied disease states of penile cancer . PLoS ONE vol. 13 , ( 6 ) e0198905 - e0198905 .

Wedge DC, Gundem G, Mitchell T, Woodcock DJ, Martincorena I, Ghori M, Zamora J, Butler A et al. ( 2018 ) . Sequencing of prostate cancers identifies new cancer genes, routes of progression and drug targets . Nature Genetics vol. 50 , ( 5 ) 682 - 692 .

Adimonye A, Stankiewicz E, Kudahetti S, Trevisan G, Tinwell B, Corbishley C, Lu YJ, Watkin N et al. ( 2018 ) . Analysis of the PI3K-AKT-mTOR pathway in penile cancer: Evaluation of a therapeutically targetable pathway . Oncotarget vol. 9 , ( 22 ) 16074 - 16086 .

Aguirre-Hernández C, Maya-Pineda H, Millán JS, Man YKS, Lu YJ, Halldén G ( 2018 ) . Sensitisation to mitoxantrone-induced apoptosis by the oncolytic adenovirus AdΔΔ through Bcl-2-dependent attenuation of autophagy . Oncogenesis vol. 7 , ( 1 )

Xu L, Bastus NC, Lu YJ ( 2018 ) . Sequencing a single circulating tumor cell for genomic assessment . Oncogenomics: From Basic Research to Precision Medicine ,

Sud A, Thomsen H, Law PJ, Försti A, Filho MIDS, Holroyd A, Broderick P, Orlando G et al. ( 2017 ) . Genome-wide association study of classical Hodgkin lymphoma identifies key regulators of disease susceptibility . Nature Communications vol. 8 , ( 1 )

Aguirre-Hernandez C, Maya-Pineda H, Millan JS, Man YKS, Lu YJ, Hallden G ( 2017 ) . Sensitisation to mitoxantrone-induced apoptosis by the oncolytic adenovirus Ad Delta Delta through Bcl-2-dependent attenuation of autophagy . HUMAN GENE THERAPY . Conference: ESGCT workshop Croatia vol. 28 , A26 - A26 .

Camacho N, Van Loo P, Edwards S, Kay JD, Matthews L, Haase K, Clark J, Dennis N et al. ( 2017 ) . Appraising the relevance of DNA copy number loss and gain in prostate cancer using whole genome DNA sequence data . PLoS Genet vol. 13 , ( 9 ) e1007001 - e1007001 .

Stankiewicz E, Xueying M, Mangham DC, Xu L, Yeste-Velasco M, Fisher G, North B, Chaplin T et al. ( 2017 ) . Identification of FBXL4 as a Metastasis Associated Gene in Prostate Cancer . Scientific Reports Article 5124 ,

Xu L, Mao X, Guo T, Chan PY, Shaw G, Hines J, Stankiewicz E, Wang Y et al. ( 2017 ) . The novel association of circulating tumor cells and circulating megakaryocytes with prostate cancer prognosis . Clin Cancer Res

Adimonye A, Stankiewicz E, Nicholson S, Hall E, Kudahetti S, Rajab R, Corbishley C, Lu Y-J et al. ( 2017 ) . 709 PIK3CA copy number aberration and activation of the PI3K-AKT-mTOR pathway in evolving disease states of penile cancer . European Urology Open Science vol. 16 , ( 3 ) e1228 - e1229 .

Berney DM, Lu YJ, Shamash J, Idrees M ( 2017 ) . Postchemotherapy changes in testicular germ cell tumours: biology and morphology . Histopathology vol. 70 , ( 1 ) 26 - 39 .

Lin HY, Chen DT, Huang PY, Liu YH, Ochoa A, Zabaleta J, Mercante DE, Fang Z et al. ( 2017 ) . SNP interaction pattern identifier (SIPI): An intensive search for SNP-SNP interaction patterns . Bioinformatics vol. 33 , ( 6 ) 822 - 833 .

Behjati S, Gundem G, Wedge DC, Roberts ND, Tarpey PS, Cooke SL, Van Loo P, Alexandrov LB et al. ( 2016 ) . Mutational signatures of ionizing radiation in second malignancies . Nature Communications vol. 7 , Article 12605 , 1 - 8 .

Jiang H, Mao X, Huang X, Zhao J, Wang L, Xu J, Zhang H, Lu Y et al. ( 2016 ) . TMPRSS2:ERG fusion gene occurs less frequently in Chinese patients with prostate cancer . Tumor Biology vol. 37 , ( 9 ) 12397 - 12402 .

Mao X, Luo F, Boyd LK, Zhou B, Zhang Y, Stankiewicz E, Marzec J, Vasiljevic N et al. ( 2016 ) . NKAIN2 functions as a novel tumor suppressor in prostate cancer . Oncotarget

Jiang H, Mao X, Huang X, Zhao J, Wang L, Xu J, Zhang H, Lu Y et al. ( 2016 ) . Erratum to: TMPRSS2:ERG fusion gene occurs less frequently in Chinese patients with prostate cancer . Tumour Biol vol. 37 , ( 10 ) 14331 - 14331 .

Stankiewicz E, Mao X, Mangham DC, Xu L, Fisher G, North B, Moller H, Scardino P et al. ( 2016 ) . Identification of FBXL4 as a bone metastasis-associated gene in prostate cancer . Scientific Reports vol. 7 ,

Winkler TW, Justice AE, Graff M, Barata L, Feitosa MF, Chu S, Czajkowski J, Esko T et al. ( 2016 ) . Correction: The Influence of Age and Sex on Genetic Associations with Adult Body Size and Shape: A Large-Scale Genome-Wide Interaction Study . PLoS Genet vol. 12 , ( 6 ) e1006166 - e1006166 .

Marzec J, Mao X, Li M, Wang M, Feng N, Gou X, Wang G, Sun Z et al. ( 2016 ) . A genetic study and meta-analysis of the genetic predisposition of prostate cancer in a Chinese population . Oncotarget vol. 7 , ( 16 ) 21393 - 21403 .

Adimonve A, Stankiewicz E, Kudahetti S, Rajab R, Corbishley C, Lu Y-J, Watkin N, Berney D ( 2016 ) . 238 PIK3CA gene copy number and mRNA expression in invasive penile cancer . European Urology Open Science vol. 15 , ( 3 )

Xu L, Mao X, Chan PY, Shamash J, Lu Y-J ( 2016 ) . Analysis of prostate cancer circulating tumour cells isolated with a novel size-based system . The Lancet . vol. 387 ,

Wang Y, Shao N, Mao X, Zhu M, Fan W, Shen Z, Xiao R, Wang C et al. ( 2016 ) . MiR-4638-5p inhibits castration resistance of prostate cancer through repressing kidins220 expression and PI3K/AKT pathway activity . Oncotarget vol. 7 , ( 30 ) 47444 - 47464 .

Imrali A, Mao X, Yeste-Velasco M, Shamash J, Lu Y ( 2016 ) . Rapamycin inhibits prostate cancer cell growth through cyclin D1 and enhances the cytotoxic efficacy of cisplatin . American Journal of Cancer Research vol. 6 , ( 8 ) 1772 - 1784 .

Zhao SC, Zhou BW, Luo F, Mao X, Lu YJ ( 2015 ) . The structure and function of NKAIN2-a candidate tumor suppressor . International Journal of Clinical and Experimental Medicine vol. 8 , ( 10 ) 17072 - 17079 .

Zhang Y, Mao XY, Liu X, Song RR, Berney D, Lu YJ, Ren G ( 2015 ) . High frequency of the SDK1:AMACR fusion transcript in Chinese prostate cancer . International Journal of Clinical and Experimental Medicine vol. 8 , ( 9 ) 15127 - 15136 .

Xu L, Mao X, Imrali A, Syed F, Mutsvangwa K, Berney D, Cathcart P, Hines J et al. ( 2015 ) . Optimization and evaluation of a novel size based circulating tumor cell isolation system . PLoS ONE vol. 10 , ( 9 )

Yeste-Velasco M, Linder ME, Lu YJ ( 2015 ) . Protein S-palmitoylation and cancer . Biochimica et Biophysica Acta - Reviews on Cancer vol. 1856 , ( 1 ) 107 - 120 .

Al Olama AA, Benlloch S, Antoniou AC, Giles G, Severi G, Neal DE, Hamdy FC, Donovan JL et al. ( 2015 ) . Risk analysis of prostate cancer in practical, a multinational consortium, using 25 known prostate cancer susceptibility loci . Cancer Epidemiology Biomarkers and Prevention vol. 24 , ( 7 ) 1121 - 1129 .

Coll-Bastus N, Mao X, Young BD, Sheer D, Lu Y-J ( 2015 ) . DNA replication-dependent induction of gene proximity by androgen . Hum Mol Genet vol. 24 , ( 4 ) 963 - 971 .

Bao JM, He MY, Liu YW, Lu YJ, Hong YQ, Luo HH, Ren ZL, Zhao SC et al. ( 2015 ) . AGE/RAGE/Akt pathway contributes to prostate cancer cell proliferation by promoting Rb phosphorylation and degradation . American Journal of Cancer Research vol. 5 , ( 5 ) 1741 - 1750 .

Lian WQ, Luo F, Song XL, Lu YJ, Zhao SC ( 2015 ) . Gonorrhea and prostate cancer incidence: An updated meta-analysis of 21 epidemiologic studies . Medical Science Monitor vol. 21 , 1895 - 1903 .

Ren G, Zhang Y, Mao X, Liu X, Mercer E, Marzec J, Ding D, Jiao Y et al. ( 2014 ) . Transcription-mediated chimeric RNAs in prostate cancer: time to revisit old hypothesis? . OMICS vol. 18 , ( 10 ) 615 - 624 .

Mercer EJ, Imrali A, Sharpe K, Hallden G, Lu Y-J ( 2014 ) . Abstract 713: Utilizing a potent and selective nonreplicating adenoviral mutant (Ad5-TV-CU), with gene expression controlled by androgen receptor-dependent activation domains in the TMPRSS2 gene, as a novel prodrug-converting enzyme therapy for prostate cancer . Conference: Experimental and Molecular Therapeutics713 - 713 .

Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljević N, Chaplin T et al. ( 2014 ) . Identification of ZDHHC14 as a novel human tumour suppressor gene . J Pathol vol. 232 , ( 5 ) 566 - 577 .

Allen MD, Luong P, Hudson C, Leyton J, Delage B, Ghazaly E, Cutts R, Yuan M et al. ( 2014 ) . Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging . Cancer Res vol. 74 , ( 3 ) 896 - 907 .

Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T et al. ( 2014 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . Cell Death Dis vol. 5 , ( 1 )

Zhang H, Fan Y, Ge N, Wang X, Sun W, Mao R, Bu W, Creighton CJ et al. ( 2014 ) . Amplification and over-expression of MAP3K3 gene in human breast cancer promotes formation and survival of breast cancer cells . Journal of Pathology vol. 232 , ( 1 ) 75 - 86 .

Zhao C-B, Bao J-M, Lu Y-J, Zhao T, Zhou X-H, Zheng D-Y, Zhao S-C ( 2014 ) . Co-expression of RAGE and HMGB1 is associated with cancer progression and poor patient outcome of prostate cancer . Am J Cancer Res vol. 4 , ( 4 ) 369 - 377 .

Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Marzec J, Vasiljevíc N, Chaplin T et al. ( 2014 ) . Erratum:Identification of ZDHHC14 as a novel human tumour suppressor gene. J Pathol (2014); 232: 566-577)) . Journal of Pathology vol. 234 , ( 1 )

Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh MT et al. ( 2014 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . Cell death & disease . vol. 5 ,

Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Marzec J, Vasiljevic N, Chaplin T, Foster JM et al. ( 2014 ) . Identification of ZDHHC14 as a novel human tumour suppressor: gene . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S90 - S90 .

Mao X, Li J, Xu X, Boyd LK, He W, Stankiewicz E, Kudahetti SC, Cao G et al. ( 2014 ) . Involvement of different mechanisms for the association of CAG repeat length polymorphism in androgen receptor gene with prostate cancer . Am J Cancer Res vol. 4 , ( 6 ) 886 - 896 .

Bastus NC, Mao X, Young BD, Sheer D, Lu Y-J ( 2014 ) . Novel function of androgen receptor-the regulation of DNA replication and genomic movement . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S89 - S89 .

Mao X, Marzec J, Li M, Zhang Z, Feng N, Gou X, Sun Z, Xu J et al. ( 2014 ) . Population differences in the genetic risk of prostate cancer and predisposition loci in the Chinese population . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S89 - S89 .

Xu L, Irrami A, Shamash J, Lu Y-J ( 2014 ) . Size-based isolation of circulating tumour cells and its application in advanced prostate cancer . INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE vol. 34 , S89 - S89 .

Sharpe K, Stewart GD, Mackay A, Van Neste C, Rofe C, Berney D, Kayani I, Bex A et al. ( 2013 ) . The effect of VEGF-targeted therapy on biomarker expression in sequential tissue from patients with metastatic clear cell renal cancer . Clin Cancer Res vol. 19 , ( 24 ) 6924 - 6934 .

Vasiljević N, Ahmad AS, Beesley C, Thorat MA, Fisher G, Berney DM, Møller H, Yu Y et al. ( 2013 ) . Association between DNA methylation of HSPB1 and death in low Gleason score prostate cancer . Prostate Cancer Prostatic Dis vol. 16 , ( 1 ) 35 - 40 .

Al Olama AA, Kote-Jarai Z, Schumacher FR, Wiklund F, Berndt SI, Benlloch S, Giles GG, Severi G et al. ( 2013 ) . A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease . HUMAN MOLECULAR GENETICS vol. 22 , ( 2 ) 408 - 415 .

Li J, Mercer E, Gou X, Lu Y-J ( 2013 ) . Ethnical disparities of prostate cancer predisposition: genetic polymorphisms in androgen-related genes . Am J Cancer Res vol. 3 , ( 2 ) 127 - 151 .

Ren G, Liu X, Mao X, Zhang Y, Stankiewicz E, Hylands L, Song R, Berney DM et al. ( 2012 ) . Identification of frequent BRAF copy number gain and alterations of RAF genes in chinese prostate cancer . Genes Chromosomes and Cancer vol. 51 , ( 11 ) 1014 - 1023 .

Boyd LK, Mao X, Lu Y-J ( 2012 ) . The complexity of prostate cancer: genomic alterations and heterogeneity . Nat Rev Urol vol. 9 , ( 11 ) 652 - 664 .

Boyd LK, Mao X, Xue L, Lin D, Chaplin T, Kudahetti SC, Stankiewicz E, Yu Y et al. ( 2012 ) . High-resolution genome-wide copy-number analysis suggests a monoclonal origin of multifocal prostate cancer . Genes Chromosomes Cancer vol. 51 , ( 6 ) 579 - 589 .

Yeste-Velasco M, Mao X, Grose R, Kudahetti SC, Lin D, Chaplin T, Xue L, Xu M et al. ( 2012 ) . Abstract 4858: Identification of ZDHHC14 as a novel tumor suppressor gene commonly downregulated in human cancers . Cancer Research vol. 72 , ( 8_Supplement ) 4858 - 4858 .

Mao X, Coll Bastus N, Boyd L, Yu Y, Ren G, Beltran L, Oliver R, Young BD et al. ( 2012 ) . The different genetic alterations between Western and Chinese prostate cancers and the underlying mechanisms . J Clin Oncol vol. 30 , ( 5_suppl )

Lu Y-J, Liu X, Mao X, Hylands L, Clark J, Cooper C, Ren G ( 2012 ) . Truncation of BRAF and Raf1 in prostate cancer in China . JOURNAL OF CLINICAL ONCOLOGY vol. 30 , ( 5 )

Lu YJ, Liu X, Mao X, Hylands L, Clark J, Cooper C, Ren G ( 2012 ) . Truncation of BRAF and Raf1 in prostate cancer in China . J Clin Oncol vol. 30 , ( 5_suppl )

Xue L, Mao X, Ren G, Stankiewicz E, Kudahetti SC, Lin D, Beltran L, Berney DM et al. ( 2012 ) . Chinese and Western prostate cancers show alternate pathogenetic pathways in association with ERG status . Am J Cancer Res vol. 2 , ( 6 ) 736 - 744 .

Ren G, Liu X, Mao X, Zhang Y, Stankiewicz E, Hylands L, Song R, Berney DM et al. ( 2012 ) . Identification of frequent BRAF copy number gain and alterations of RAF genes in chinese prostate cancer . Genes Chromosomes and Cancer

Kote-Jarai Z, Al Olama AA, Giles GG, Severi G, Schleutker J, Weischer M, Campa D, Riboli E et al. ( 2011 ) . Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study . NAT GENET vol. 43 , ( 8 ) 785 - U96 .

Lu YJ, Mao X, Yu Y, Boyd LK, Oliver RTD, Berney DM ( 2011 ) . Distinct genomic differences in prostate cancer between western countries and china . BRITISH JOURNAL OF SURGERY . vol. 98 , E3 - E3 .

Bastus NC, Lu Y-J, Boyd LK, Mao X, Stankiewicz E, Kudahetti SC, Oliver TD, Berney DM ( 2011 ) . Abstract 3048: Enhanced androgen signalling pathway increases the risk of prostate cancer through induction of TMPRSS2:ERG fusion . Cancer Research vol. 71 , ( 8_Supplement ) 3048 - 3048 .

Lu Y-J, Mao X, Xue L, Boyd LK, Kudahetti SC, Yu Y, Ren G, Lin D et al. ( 2011 ) . Abstract 3878: The different genetic alterations between Western and Chinese samples indicate alternate pathways of prostate cancer development . Cancer Research vol. 71 , ( 8_Supplement ) 3878 - 3878 .

Boyd LK, Xue L, Mao X, Lin D, Chaplin T, Kudahetti SC, Stankiewicz E, Bisson I et al. ( 2011 ) . Abstract 4831: Monoclonal origin of multifocal cancer and the step-wise genetic events of prostate carcinogenesis . Cancer Research vol. 71 , ( 8_Supplement ) 4831 - 4831 .

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