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Research

Publications: Prof Rizgar Mageed

Clanchy FIL, Borghese F, Bystrom J, Balog A, Penn H, Taylor PC, Stone TW, Mageed RA et al. ( 2022 ) . Disease status in human and experimental arthritis, and response to TNF blockade, is associated with MHC class II invariant chain (CD74) isoform expression . Journal of Autoimmunity vol. 128 , 102810 - 102810 .
Clanchy FIL, Borghese F, Bystrom J, Balog A, Penn H, Hull DN, Wells GMA, Kiriakidis S et al. ( 2021 ) . TLR expression profiles are a function of disease status in rheumatoid arthritis and experimental arthritis . Journal of Autoimmunity vol. 118 ,
Al-Bogami M, Bystrom J, Clanchy F, Taher TE, Mangat P, Williams RO, Jawad AS, Mageed RA ( 2021 ) . TNFα inhibitors reduce bone loss in rheumatoid arthritis independent of clinical response by reducing osteoclast precursors and IL-20 . Rheumatology (United Kingdom) vol. 60 , ( 2 ) 947 - 957 .
Taher TE, Bystrom J, Mignen O, Pers JO, Renaudineau Y, Mageed RA ( 2020 ) . CD5 and B lymphocyte responses: multifaceted effects through multitudes of pathways and channels . Cellular and Molecular Immunology vol. 17 , ( 11 ) 1201 - 1203 .
Bystrom J, Taher TE, Mageed RA ( 2020 ) . Metabolic Pathways Underpinning Lymphocyte Differentiation and Responses in Health and Disease . Immunometabolism vol. 2 , ( 3 )
Bystrom J, Clanchy FIL, Taher TE, Al-Bogami M, Ong VH, Abraham DJ, Williams RO, Mageed RA ( 2019 ) . Functional and phenotypic heterogeneity of Th17 cells in health and disease . European Journal of Clinical Investigation vol. 49 , ( 1 )
Garaud S, Taher TE, Debant M, Burgos M, Melayah S, Berthou C, Parikh K, Pers JO et al. ( 2018 ) . CD5 expression promotes IL-10 production through activation of the MAPK/Erk pathway and upregulation of TRPC1 channels in B lymphocytes . Cellular and Molecular Immunology vol. 15 , ( 2 ) 158 - 170 .
Bystrom J, Clanchy FI, Taher TE, Mangat P, Jawad AS, Williams RO, Mageed RA ( 2018 ) . TNFα in the regulation of Treg and Th17 cells in rheumatoid arthritis and other autoimmune inflammatory diseases . Cytokine vol. 101 , 4 - 13 .
Taher TE, Ong VH, Bystrom J, Hillion S, Simon Q, Denton CP, Pers J-O, Abraham DJ et al. ( 2017 ) . Defective regulation of autoreactive IL-6-producing transitional B lymphocytes is associated with disease in patients with systemic sclerosis . Arthritis Rheumatol
Taher TE, Bystrom J, Ong VH, Isenberg DA, Renaudineau Y, Abraham DJ, Mageed RA ( 2017 ) . Intracellular B Lymphocyte Signalling and the Regulation of Humoral Immunity and Autoimmunity . Clin Rev Allergy Immunol vol. 53 , ( 2 ) 237 - 264 .
Bystrom J, Clanchy FI, Taher TE, Al-Bogami MM, Muhammad HA, Alzabin S, Mangat P, Jawad AS et al. ( 2017 ) . Response to Treatment with TNFα Inhibitors in Rheumatoid Arthritis Is Associated with High Levels of GM-CSF and GM-CSF+ T Lymphocytes . Clin Rev Allergy Immunol vol. 53 , ( 2 ) 265 - 276 .
Clanchy FI, Williams RO, Mageed RA ( 2017 ) . Lymphocytes: Precursor Frequencies . eLS ,
Al-Bogami MM, Alkhorayef MA, Bystrom J, Akanle OA, Al-Adhoubi NK, Jawad AS, Mageed RA ( 2015 ) . Favorable therapeutic response of osteoporosis patients to treatment with intravenous zoledronate compared with oral alendronate . Saudi Medical Journal vol. 36 , ( 11 ) 1305 - 1311 .
Simon Q, Pers J-O, Cornec D, Le Pottier L, Mageed RA, Hillion S ( 2015 ) . In-depth characterization of CD24highCD38high transitional human B cells reveals different regulatory profiles . Journal of Allergy and Clinical Immunology vol. 137 , ( 5 ) 1577 - 1584.e10 .
Simon Q, Pers J-O, Cornec D, Rizgar MA, Hillion S ( 2015 ) . AB0032 In-Depth Characterization of Cd24Highcd38High Transitional Human B Cells Reveals Different Regulatory Profiles and Are Abnormally Distributed in Autoimmune Diseases . Annals of the Rheumatic Diseases vol. 74 , ( Suppl 2 )
Simon Q, Cornec D, Mageed R, Pers JO, Hillion S ( 2015 ) . In-Depth Characterization of CD24(high)CD38(high) Transitional Human B Cells Reveals Different Regulatory Profiles and are Abnormally Distributed in Sjogren's Syndrome . SCANDINAVIAN JOURNAL OF IMMUNOLOGY . vol. 81 , 378 - 378 .
Hillion S, Simon Q, Cornec D, Mageed R, Pers J ( 2015 ) . A1.21 In-depth characterisation of CD24highCD38high transitional human B cells reveals different regulatory profiles . Annals of the Rheumatic Diseases . vol. 74 , a9 - a9 .
Bystrom J, Taher TE, Muhyaddin MS, Clanchy FI, Mangat P, Jawad AS, Williams RO, Mageed RA ( 2015 ) . Harnessing the Therapeutic Potential of Th17 Cells . Mediators of Inflammation vol. 2015 ,
Bystrom J, Taher T, Al-Bogami M, Alzabin S, Kelly S, Mangat P, Williams R, Jawad A et al. ( 2014 ) . THU0500 Cytokine Production Identifies A Subset of Rheumatoid Arthritis Patients T Lymphocytes That is Associated with Responsiveness to Biologic Anti-TNF-Alpha Agents . Annals of the Rheumatic Diseases . vol. 73 ,
Muhammad H, Taher T, Mullen L, Pastan I, Marshall J, Chernajovsky Y, Gould D, Mageed R ( 2014 ) . Development of a novel approach for targeted delivery of siRNA to B lymphocytes with a potential application in cancer . HUMAN GENE THERAPY . vol. 25 , A5 - A5 .
Albogami MM, Jawad AS, Mageed RA ( 2014 ) . Bone loss in osteoporosis and arthritis . SAUDI MEDICAL JOURNAL vol. 35 , ( 3 ) 224 - 233 .
Albogami MM, Jawad AS, Mageed RA ( 2014 ) . Bone loss in osteoporosis and arthritis. Pathogenesis and therapeutic strategies . Saudi Med J vol. 35 , ( 3 ) 224 - 233 .
Taher TE, Muhammad HA, Rahim A, Flores-Borja F, Renaudineau Y, Isenberg DA, Mageed RA ( 2013 ) . Aberrant B-lymphocyte responses in lupus: inherent or induced and potential therapeutic targets . Eur J Clin Invest vol. 43 , ( 8 ) 866 - 880 .
Taher TE, Muhammad HA, Bariller E, Flores-Borja F, Renaudineau Y, Isenberg DA, Mageed RA ( 2013 ) . B-lymphocyte signalling abnormalities and lupus immunopathology . Int Rev Immunol vol. 32 , ( 4 ) 428 - 444 .
Muhammad H, Taher T, Mullen L, Pastan I, Chernajovsky Y, Gould D, Mageed R ( 2013 ) . Generation of a secreted scFv for specific delivery of siRNA to B-lymphocytes . HUMAN GENE THERAPY . vol. 24 , A36 - A36 .
Bystrom J, Al-Adhoubi N, Al-Bogami M, Jawad AS, Mageed RA ( 2013 ) . Th17 lymphocytes in respiratory syncytial virus infection . Viruses vol. 5 , ( 3 ) 777 - 791 .
Nordin NI, Gibbons S, Perrett D, Mageed RA, Nafiah MA ( 2013 ) . Immunomodulatory Effects of Roscoe var. (Halia Bara) ON Inflammatory Responses Relevant to Psoriasis . The Open Conference Proceedings Journal vol. 4 , ( 1 ) 76 - 76 .
Al-Bogami MM, Alkhorayef MA, Akanle OA, Jawad AS, Mageed RA ( 2013 ) . The effects of smoking on response of osteoporosis treatment using dual energy X-ray absorptiometry scans, invited . Transactions of the American Nuclear Society . vol. 109 , 51 - 52 .
Alzabin S, Abraham SM, Taher TE, Palfreeman A, Hull D, McNamee K, Jawad A, Pathan E et al. ( 2012 ) . Incomplete response of inflammatory arthritis to TNF alpha blockade is associated with the Th17 pathway . ANNALS OF THE RHEUMATIC DISEASES vol. 71 , ( 10 ) 1741 - 1748 .
Alzabin S, Abraham SM, Taher TE, Palfreeman A, Hull D, McNamee K, Jawad A, Pathan E et al. ( 2012 ) . Incomplete response of inflammatory arthritis to TNFα blockade is associated with the Th17 pathway . Ann Rheum Dis vol. 71 , ( 10 ) 1741 - 1748 .
Thabet Y, Cañas F, Ghedira I, Youinou P, Mageed RA, Renaudineau Y ( 2012 ) . Altered patterns of epigenetic changes in systemic lupus erythematosus and auto-antibody production: is there a link? . J Autoimmun vol. 39 , ( 3 ) 154 - 160 .
Mageed RA, Garaud S, Taher TE, Parikh K, Pers J-O, Jamin C, Renaudineau Y, Youinou P ( 2012 ) . CD5 expression promotes multiple intracellular signaling pathways in B lymphocyte . Autoimmun Rev vol. 11 , ( 11 ) 795 - 798 .
Campbell R, Hofmann D, Hatch S, Gordon P, Lempp H, Das L, Blumbergs P, Limaye V et al. ( 2012 ) . Muscle disorders111. The impact of fatigue in patients with idiopathic inflammatory myopathy: a mixed method study . Rheumatology vol. 51 , ( suppl_3 ) iii93 - iii139 .
Nordin NI, D'acquisto F, Gibbons S, Perrett D, Mageed RA ( 2011 ) . Potent anti-inflammatory compounds identified in Zingiber officinale Roscoe var. rubrum Theilade: Mechanisms of action in psoriasis . PLANTA MEDICA . vol. 77 , 1422 - 1423 .
Garaud S, Morva A, Lemoine S, Hillion S, Bordron A, Pers J-O, Berthou C, Mageed RA et al. ( 2011 ) . CD5 promotes IL-10 production in chronic lymphocytic leukemia B cells through STAT3 and NFAT2 activation . J Immunol vol. 186 , ( 8 ) 4835 - 4844 .
Mittal GA, Mageed RA, Chernajovsky Y ( 2011 ) . HUMAN (H161R) IL-17F MUTANT IS A DUAL ANTAGONIST OF IL-17A AND IL-17F . RHEUMATOLOGY . vol. 50 , 53 - 53 .
Nesbitt A, Fossati G, Whittall CE, Askari A, Middleton J, Astorri E, Bombardi M, Peakman M et al. ( 2011 ) . Cytokines and inflammatory mediators25. Certolizumab Pegol has a Different Profile from the other Anti-TNFS, Including Golimumab, in a Variety of in Vitro Assays . Rheumatology vol. 50 , ( suppl_3 ) iii52 - iii55 .
Nordin NI, D'Acquisto F, Gibbons S, Perrett D, Mageed RA ( 2010 ) . Immune-modulatory effects of compounds isolated from Zingiber officinale Roscoe (var. rubrum Theilade) on immune mechanisms associated with psoriasis . IMMUNOLOGY . vol. 131 , 65 - 65 .
Séïté J-F, Cornec D, Renaudineau Y, Youinou P, Mageed RA, Hillion S ( 2010 ) . IVIg modulates BCR signaling through CD22 and promotes apoptosis in mature human B lymphocytes . Blood vol. 116 , ( 10 ) 1698 - 1704 .
Taher TE, Parikh K, Flores-Borja F, Mletzko S, Isenberg DA, Peppelenbosch MP, Mageed RA ( 2010 ) . Protein phosphorylation and kinome profiling reveal altered regulation of multiple signaling pathways in B lymphocytes from patients with systemic lupus erythematosus . Arthritis Rheum vol. 62 , ( 8 ) 2412 - 2423 .
Mageed RA, Taher TE, Jawad AS ( 2010 ) . Disease mechanisms, genetic susceptibility and therapeutic approaches in lupus disease .
Garaud S, Le Dantec C, de Mendoza AR, Mageed RA, Youinou P, Renaudineau Y ( 2009 ) . IL-10 production by B cells expressing CD5 with the alternative exon 1B . Ann N Y Acad Sci vol. 1173 , 280 - 285 .
Alard J-E, Dueymes M, Mageed RA, Saraux A, Youinou P, Jamin C ( 2009 ) . Mitochondrial heat shock protein (HSP) 70 synergizes with HSP60 in transducing endothelial cell apoptosis induced by anti-HSP60 autoantibody . FASEB J vol. 23 , ( 8 ) 2772 - 2779 .
Youinou P, Taher TE, Pers J-O, Mageed RA, Renaudineau Y ( 2009 ) . B lymphocyte cytokines and rheumatic autoimmune disease . Arthritis Rheum vol. 60 , ( 7 ) 1873 - 1880 .
Garaud S, Le Dantec C, Jousse-Joulin S, Hanrotel-Saliou C, Saraux A, Mageed RA, Youinou P, Renaudineau Y ( 2009 ) . IL-6 modulates CD5 expression in B cells from patients with lupus by regulating DNA methylation . J Immunol vol. 182 , ( 9 ) 5623 - 5632 .
Rochas C, Hillion S, Saraux A, Mageed RA, Youinou P, Jamin C, Devauchelle V ( 2009 ) . Transmembrane BAFF from rheumatoid synoviocytes requires interleukin-6 to induce the expression of recombination-activating gene in B lymphocytes . Arthritis Rheum vol. 60 , ( 5 ) 1261 - 1271 .
Mageed RA, Mletzko S, Varin M, Duchene J, Taher T, Warnes G, Jawad AS, Isenberg DA ( 2009 ) . ALTERED MEMBRANE CD45 ISOFORM EXPRESSION AND INTRACELLULAR SIGNALLING DEFECTS IN B CELLS FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS(SLE) . RHEUMATOLOGY . vol. 48 , I32 - I32 .
Jawad AS, Taher TE, Rahim A, D'Acquisto F, Gould D, Mageed RA ( 2009 ) . SELECTIVE TARGETING OF THE CANONICAL OR ALTERNATIVE NF-kappa B PATHWAY REVEALS NEW INSIGHTS INTO MECHANISMS OF B-LYMPHOCYTE SURVIVAL AND SELECTION . RHEUMATOLOGY . vol. 48 , I30 - I31 .
Habib HM, Taher TE, Isenberg DA, Mageed RA ( 2009 ) . Enhanced propensity of T lymphocytes in patients with systemic lupus erythematosus to apoptosis in the presence of tumour necrosis factor alpha . Scand J Rheumatol vol. 38 , ( 2 ) 112 - 120 .
Mletzko S, Varin MM, Duchene J, Taher T, Warnes G, Isenberg DA, Mageed RA ( 2008 ) . Altered membrane expression levels of distinct CD45RB isoforms are associated with B cell hyperactivity in systemic lupus erythematosus (SLE) . IMMUNOLOGY . vol. 125 , 41 - 41 .
Youinou P, Taher T, Mankai A, Berthou C, Mageed R ( 2008 ) . Anti-CD20 in Targeting B Lymphocytes for the Treatment of Autoimmune Diseases: Clinical Benefits and Insights into the Role of B Lymphocytes in Pathophysiology . Immunology Endocrine & Metabolic Agents - Medicinal Chemistry vol. 8 , ( 3 ) 222 - 234 .
Mageed RA ( 2008 ) . New strategies and biological agents in the treatment of autoimmune inflammatory diseases. Progress and challenges . Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry vol. 8 , ( 3 ) 191 - 199 .
Taher TE, Tulone C, Fatah R, D'Acquisto F, Gould DJ, Mageed RA ( 2008 ) . Repopulation of B-lymphocytes with restricted gene expression using haematopoietic stem cells engineered with lentiviral vectors . Gene Ther vol. 15 , ( 13 ) 998 - 1006 .
Jawad AS, Mangat P, Perry D, Mageed RA ( 2008 ) . Anti-TNF alpha-based therapy in rheumatoid arthritis (RA): Mechanisms of action and possible causes of non-responsiveness . RHEUMATOLOGY . vol. 47 , II37 - II38 .
Zouali M, Mageed RA ( 2008 ) . Cellular interactions and signalling defects in lupus(1) . LUPUS vol. 17 , ( 3 ) 236 - 240 .
Flores-Borja F, Kabouridis PS, Jury EC, Isenberg DA, Mageed RA ( 2007 ) . Altered lipid raft-associated proximal signaling and translocation of CD45 tyrosine phosphatase in B lymphocytes from patients with systemic lupus erythematosus . Arthritis Rheum vol. 56 , ( 1 ) 291 - 302 .
Flores-Borja F, Kabouridis PS, Jury EC, Isenberg DA, Mageed RA ( 2006 ) . Lyn dericiency in B cells from patients with systemic lupus erythematosus: comment on the article by Flores-Borja et al - Reply . ARTHRITIS RHEUM vol. 54 , ( 6 ) 2037 - 2038 .
Flores-Borja F, Kabouridis PS, Jury EC, Isenberg DA, Mageed RA ( 2005 ) . Decreased Lyn expression and translocation to lipid raft signaling domains in B lymphocytes from patients with systemic lupus erythematosus . Arthritis Rheum vol. 52 , ( 12 ) 3955 - 3965 .
Renaudineau Y, Hillion S, Saraux A, Mageed RA, Youinou P ( 2005 ) . An alternative exon 1 of the CD5 gene regulates CD5 expression in human B lymphocytes . BLOOD vol. 106 , ( 8 ) 2781 - 2789 .
Flores-Borja F, Kabouridis PS, Jury E, Isenberg D, Mageed RA ( 2005 ) . Translocation of CD45 to lipid raft signalling domains and abnormal relocation during B-lymphocyte activation in SLE . RHEUMATOLOGY . vol. 44 , I17 - I17 .
Jury EC, Kabouridis PS, Flores-Borja F, Mageed RA, Isenberg DA ( 2004 ) . ALTERED LIPID RAFT EXPRESSION AND ASSOCIATED SIGNALLING IN T LYMPHOCYTES FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) . RHEUMATOLOGY . vol. 43 , 24 - 24 .
Flores-Borja F, Kabouridis PS, Jury E, Isenberg D, Mageed RA ( 2004 ) . ATYPICAL CO-LOCALISATION OF CD45 AND LYN TO LIPID RAFT SIGNALLING DOMAINS CORRELATES WITH B-LYMPHOCYTE HYPER RESPONSIVENESS IN PATIENTS WITH LUPUS . RHEUMATOLOGY . vol. 43 , 108 - 108 .
Kabouridis PS, MAGEED R, Flores-Borja F, Isenberg DA, Jury EC ( 2004 ) . Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus . Journal of Clinical Investigation vol. 113 , ( 8 ) 1176 - 1187 .
Jury EC, Kabouridis PS, Flores-Borja F, Mageed RA, Isenberg DA ( 2004 ) . Altered lipid raft-associated signaling and ganglioside expression in T lymphocytes from patients with systemic lupus erythematosus . J Clin Invest vol. 113 , ( 8 ) 1176 - 1187 .
Mackworth-Young CG, Harmer IJ, Mageed RA ( 2003 ) . The role of antigen in the selection of the human V3-23 immunoglobulin heavy chain variable region gene . Clin Exp Immunol vol. 134 , ( 3 ) 420 - 425 .
Jury EC, Kabouridis PS, Flores-Borja F, Mageed RA, Isenberg DA ( 2003 ) . Abnormal co-localisation of CD45 and lipid rafts is associated with reduced LCK expression in T cells from patients with SLE . ARTHRITIS AND RHEUMATISM . vol. 48 , S193 - S193 .
Mageed RA, Prud'homme GJ ( 2003 ) . Immunopathology and the gene therapy of lupus . GENE THER vol. 10 , ( 10 ) 861 - 874 .
Jury EC, Kabouridis PS, Abba A, Mageed RA, Isenberg DA ( 2003 ) . Increased ubiquitination and reduced expression of LCK in T lymphocytes from patients with systemic lupus erythematosus . ARTHRITIS RHEUM vol. 48 , ( 5 ) 1343 - 1354 .
Flores-Borja F, Kabouridis PS, Jury E, Isenberg D, Mageed RA ( 2003 ) . ANALYSIS OF LIPID RAFT-ASSOCIATED SIGNALLING MOLECULES IN B CELLS FROM NORMAL AND PATIENTS WITH SLE . RHEUMATOLOGY . vol. 42 , 72 - 73 .
Jury EC, Kabouridis PS, Flores-Borja F, Mageed RA, Isenberg DA ( 2003 ) . CD45 IS ABNORMALLY ASSOCIATED WITH LIPID RAFTS IN T LYMPHOCYTES FROM PATIENTS WITH SYSTEMIC LUPUS ERYTHEMATOSUS (SLE) . RHEUMATOLOGY . vol. 42 , 5 - 5 .
Williams RO, Ahmed S, Isenberg DA, Mageed RA ( 2003 ) . DEFICIENCY IN A-KINASE ANCHOR PROTEIN EXPRESSION IN PERIPHERAL BLOOD LEUKOCYTES FROM PATIENTS WITH SLE . RHEUMATOLOGY vol. 42 , 73 - 73 .
MAGEED R, Lydyard PM, Youinou P ( 2002 ) . B cells underpin lupus immunopathology . Lupus vol. 11 , ( 1 ) 1 - 3 .
Mageed RA, Zack DJ ( 2002 ) . Cross-reactivity and pathogenicity of anti-DNA autoantibodies in systemic lupus erythematosus . LUPUS . vol. 11 , 783 - 786 .
MAGEED R, Zack DJ ( 2002 ) . Cross-reactivity and pathogenicity of anti-DNA autoantibodies in systemic lupus erythematosus . Lupus vol. 11 , 783 - 786 .
MAGEED R, Ruzickova S, Zd'arsky E, Vencovsky J, Moyes SP, Hajeer A, Ollier WE, Maini RN et al. ( 2002 ) . Polymorphism in the immunoglobulin VH gene V1-69 affects susceptibility to rheumatoid arthritis in subjects lacking the HLA-DRB1 shared epitope . Rheumatology vol. 41 , 401 - 410 .
Mageed RA, Isenberg DA ( 2002 ) . Tumour necrosis factor alpha in systemic lupus erythematosus and anti-DNA autoantibody production . LUPUS vol. 11 , ( 12 ) 850 - 855 .
MAGEED R, Jarosova K, Ozen S, Nemcova D, Niederlova J, Ruzickova S, Ollier W, Vencovsky J ( 2001 ) . Higher Frequency of Allele 2 of the Interleukin-1 Receptor Antagonist Gene in Patients With Juvenile Idiopathic Arthritis . Arthritis and Rheumatism vol. 44 , ( 10 ) 2387 - 2391 .
MAGEED R, Mackworth-Young CG, Maziak BB, Wynn SL, Harmer IJ, Moyes SP, Bruggemann M ( 2001 ) . Rearrangement of the human heavy chain variable region gene V3-23 in transgenic mice generates antibodies reactive with a range of antigens on the basis of VHCDR3 and residues intrinsic to the heavy chain variable region . Clin Exp Immunol vol. 123 , 1 - 8 .
MAGEED R, Renaudineau Y, Pers JO, Kulikova N, Jamin C, Porakishvili N, Youinou P, Lydyard PM ( 2001 ) . Recent progress in the understanding of B-cell functions in autoimmunity . Scand J Immunol. vol. 54 , 30 - 38 .
MAGEED R, Mackworth-Young CG, Mason AN ( 2001 ) . The effects of a human IgM monoclonal anticardiolipin antibody on pregnancy in a transgenic mouse model . Lupus vol. 10 , 289 - 294 .
Suleyman S, Thompson KM, Mageed RA, Natvig JB ( 2000 ) . Molecular analysis of human immunoglobulin heavy chain variable region associated determinants recognized by anti-VH3 antibodies 7B4, B6 and D12 . Scandinavian Journal of Immunology vol. 52 , ( 4 ) 341 - 347 .
Lettesjö H, Burd GP, Mageed RA ( 2000 ) . CD4<sup>+</sup> T lymphocytes with constitutive CD40 ligand in preautommune (NZB × NZW)F<inf>1</inf> lupus-pro mice: Phenotype and possible role in autoreactivity . Journal of Immunology vol. 165 , ( 7 ) 4095 - 4104 .
Gharagozloo S, Sharifian RA, Mageed RA, Shokri F ( 2000 ) . Analysis of the expressed immunoglobulin variable region heavy chain gene products in paraproteins from Iranian patients with multiple myeloma . Pathology and Oncology Research vol. 6 , ( 3 ) 185 - 190 .
Chernajovsky Y, Dreja H, Daly G, Annenkov A, Gould D, Adams G, Croxford JL, Baker D et al. ( 2000 ) . Immuno- and genetic therapy in autoimmune diseases . Genes and Immunity vol. 1 , ( 5 ) 295 - 307 .
Williams DG, Moyes SP, Mageed RA ( 1999 ) . Rheumatoid factor isotype switch and somatic mutation variants within rheumatoid arthritis synovium . Immunology vol. 98 , ( 1 ) 123 - 136 .
Axford JS, Rees DHE, Mageed RA, Wordsworth P, Alavi A, Steere AC ( 1999 ) . Increased IgA rheumatoid factor and V(H)1 associated cross reactive idiotype expression in patients with Lyme arthritis and neuroborreliosis . Annals of the Rheumatic Diseases vol. 58 , ( 12 ) 757 - 761 .
Potter KN, Li Y, Mageed RA, Jefferis R, Capra JD ( 1999 ) . Molecular characterization of the V(H)1-specific variable region determinants recognized by anti-idiotypic monoclonal antibodies G6 and G8 . Scandinavian Journal of Immunology vol. 50 , ( 1 ) 14 - 20 .
Mason AN, Harmer IJ, Mageed RA, Mackworth-Young CG ( 1999 ) . The BH1 idiotype defines a population of anticardiolipin antibodies closely associated with the antiphospholipid syndrome . Lupus vol. 8 , ( 3 ) 234 - 239 .
Annenkov AE, Moyes SP, Eshhar Z, Mageed RA, Chernajovsky Y ( 1998 ) . Loss of original antigenic specificity in T cell hybridomas transduced with a chimeric receptor containing single-chain Fv of an anti-collagen antibody and FcεRI-signaling γ subunit . Journal of Immunology vol. 161 , ( 12 ) 6604 - 6613 .
Potter KN, Li Y, Mageed RA, Jefferis R, Capra JD ( 1998 ) . Anti-idiotypic antibody D12 and superantigen SPA both interact with human V(h)3-encoded antibodies on the external face of the heavy chain involving FR1, CDR2 and FR3 . Molecular Immunology vol. 35 , ( 18 ) 1179 - 1187 .
Melero J, Aguilera I, Mageed RA, Jefferis R, Tarragó D, Núñez-Roldán A, Sánchez B ( 1998 ) . The frequent expansion of a subpopulation of B cells that express RF- associated cross-reactive idiotypes: Evidence from analysis of a panel of autoreactive monoclonal antibodies . Scandinavian Journal of Immunology vol. 48 , ( 2 ) 152 - 158 .
Moyes SP, Maini RN, Mageed RA ( 1998 ) . Differential use of immunoglobulin light chain genes and B lymphocyte expansion at sites of disease in rheumatoid arthritis (RA) compared with circulating B lymphocytes . Clinical and Experimental Immunology vol. 113 , ( 2 ) 276 - 288 .
Hajeer AH, Lazarus M, Turner D, Mageed RA, Vencovsky J, Sinnott P, Hutchinson IV, Ollier WER ( 1998 ) . IL-10 gene promoter polymorphisms in rheumatoid arthritis . Scandinavian Journal of Rheumatology vol. 27 , ( 2 ) 142 - 145 .
Chernajovsky Y, Annenkov A, Herman C, Triantaphyllopoulos K, Gould D, Dreja H, Moyes SP, Croxford JL et al. ( 1998 ) . Gene therapy for rheumatoid arthritis. Theoretical considerations . Drugs and Aging vol. 12 , ( 1 ) 29 - 41 .
Abadi J, Friedman J, Mageed RA, Jefferis R, Rodriguez-Barradas MC, Pirofski LA ( 1998 ) . Human antibodies elicited by a pneumococcal vaccine express ldiotypic determinants indicative of V(H)3 gene segment usage . Journal of Infectious Diseases vol. 178 , ( 3 ) 707 - 716 .
Mageed RA, Adams G, Woodrow D, Podhajcer OL, Chernajovsky Y ( 1998 ) . Prevention of collagen-induced arthritis by gene delivery of soluble p75 tumour necrosis factor receptor . Gene Therapy vol. 5 , ( 12 ) 1584 - 1592 .
Gharagozloo S, Mageed RA, Stevenson FK, Shokri F ( 1997 ) . Analysis of immunoglobulin variable region heavy (VH) and light (VL) chain gene products in paraproteins isolated from Iranian patients with multiple myeloma . Immunology Letters vol. 56 , 323 - 324 .
Vencovský J, Maini RN, Ollier WE, Mageed RA ( 1997 ) . Immunoglobulin variable region (IgV) gene expression in rheumatoid factors from monozygotic twins with rheumatoid arthritis . Annals of the New York Academy of Sciences vol. 815 , 324 - 326 .
Mageed RA, Moyes SP, Thompson KM, Natvig JB ( 1997 ) . Molecular and Cellular Aspects of Human Rheumatoid Factor Production and Idiotypes . Idiotypes in Medicine: Autoimmunity, Infection and Cancer ,
Mageed RA, Børretzen M, Moves SP, Thompson KM, Natvig JB ( 1997 ) . Rheumatoid factor autoantibodies in health and disease . Annals of the New York Academy of Sciences vol. 815 , 296 - 311 .
Mageed RA, Moves SP, Vencovský J, Maini RN ( 1997 ) . Somatic mutation and CDR3 length of immunoglobulin lambda variable region genes in the synovium of patients with rheumatoid arthritis . Annals of the New York Academy of Sciences vol. 815 , 319 - 323 .
de Sá Oliveira GG, Izui S, Ravirajan CT, Mageed RA, Lydyard PM, Elson CJ, Barker RN ( 1996 ) . Diverse antigen specificity of erythrocyte-reactive monoclonal autoantibodies from NZB mice . Clin Exp Immunol vol. 105 , ( 2 ) 313 - 320 .
Moyes SP, Brown CM, Scott BB, Maini RN, Mageed RA ( 1996 ) . Analysis of V(κ) genes in rheumatoid arthritis (RA) synovial B lymphocytes provides evidence for both polyclonal activation and antigen- driven selection . Clinical and Experimental Immunology vol. 105 , ( 1 ) 89 - 98 .
Harmer IJ, Mageed RA, Kaminski A, Charles P, Brüggemann M, Mackworth-Young CG ( 1996 ) . Chimaeric monoclonal antibodies encoded by the human V<inf>H</inf>26 gene from naïve transgenic mice display a wide range of antigen-binding specificities . Immunology vol. 88 , ( 2 ) 174 - 182 .
Mageed RA ( 1996 ) . The RF antigen . Manual of Biological Markers of Disease ,
Macgregor AJ, Bamber S, Carthy D, Vencovsky J, Mageed RA, Ollier WER, Silman AJ ( 1995 ) . Heterogeneity of disease phenotype in monozygotic twins concordant for rheumatoid arthritis . Rheumatology vol. 34 , ( 3 ) 215 - 220 .
VENCOVSKY J, MAGEED RA, OLLIER WE, MAINI RN ( 1995 ) . Monozygotic Rheumatoid Arthritis Twin Pairs Express Similar Levels of Conserved Immunoglobulin V Gene in Polyclonal Rheumatoid Factors Irrespective of Disease Status . Scandinavian Journal of Immunology vol. 42 , ( 1 ) 147 - 157 .
MacGregor AJ, Ollier WER, Venkovsky J, Mageed RA, Carthy D, Silman AJ ( 1995 ) . Rheumatoid factor isotypes in monozygotic and dizygotic twins discordant for rheumatoid arthritis . Journal of Rheumatology vol. 22 , ( 12 ) 2203 - 2207 .
Brown CMS, Fitzgerald KJ, Moyes SP, Mageed RA, Williams DG, Maini RN ( 1995 ) . Sequence analysis of immunoglobulin heavy-chain variable region genes from the synovium of a rheumatoid arthritis patient shows little evidence of mutation but diverse CDR3 . Immunology vol. 84 , ( 3 ) 367 - 374 .
Mageed RA, Vencovsky J, Maini RN ( 1994 ) . Rheumatoid factors and germline genes in rheumatoid arthritis: Evidence of an intrinsic b-lymphocyte defect? . Rheumatology vol. 33 , ( 2 ) 105 - 107 .
SCOTT BB, SADIGH S, ANDREW EM, MAINI RN, MAGEED RA ( 1994 ) . Affinity Maturation and Isotype Switch in Clonally Related Anti‐Erythrocyte Autoantibodies . Scandinavian Journal of Immunology vol. 40 , ( 1 ) 16 - 21 .
Moazzeni M, Mosayyebi G, Stevenson FK, Abbot S, Mageed RA, Shokri F ( 1994 ) . Biased utilization of immunoglobulin variable region heavy‐ and light‐chain genes by the malignant CD5‐ B lymphocytes from patients with Burkitt's lymphoma . International Journal of Cancer vol. 58 , ( 2 ) 226 - 232 .
Sadigh S, Scott BB, Mageed RA, Malcolm A, Andrew EM, Maini RN ( 1994 ) . Identification of hybridomas derived from mouse CD5<sup>+</sup> B lymphocytes by fluorescent staining for cytoplasmic CD5 expression . Immunology vol. 81 , ( 4 ) 558 - 563 .
MAGEED R ( 1994 ) . The RF antigen . Manual of Biological Markers of Disease , Editors: Venrooij, WJV, Maini, RN , vol. 1 , Kluwer Academic Publishers
SULEYMAN S, THOMPSON KM, FØRRE, SIOUD M, RANDEN I, MAGEED RA, NATVIG JB ( 1994 ) . Three New Cross‐Reacting Idiotopes as Markers for the Products of Two Distinct Human V<inf>H</inf>3 Genes Expressed in the Early Repertoire . Scandinavian Journal of Immunology vol. 40 , ( 6 ) 681 - 690 .
Shokri F, Mageed RA, Jefferis R ( 1993 ) . A quantitative elisa for measurement of rheumatoid factor associated cross-reactive idiotypes in serum from patients with rheumatic diseases . Rheumatology vol. 32 , ( 10 ) 862 - 869 .
Scott BB, Sadigh S, Stow M, Mageed RAK, Andrew EM, Maini RN ( 1993 ) . Anti-mouse red blood cell monoclonal antibodies use functionally rearranged genes from V(H) J558 family and are derived from the CD5<sup>-</sup> B-lymphocyte subpopulation . Immunology vol. 79 , ( 4 ) 568 - 573 .
Lydyard PM, Lamour A, MacKenzie LE, Jamin C, Mageed RA, Youinou P ( 1993 ) . CD5<sup>+</sup> B cells and the immune system . Immunology Letters vol. 38 , ( 2 ) 159 - 166 .
YOUINOU P, MACKENZIE LE, LAMOUR A, MAGEED RA, LYDYARD PM ( 1993 ) . Human CD5‐positive B Cells in lymphoid malignancy and connective tissue diseases . European Journal of Clinical Investigation vol. 23 , ( 3 ) 139 - 150 .
Shokri F, Mageed RA, Richardson P, Jefferis R ( 1993 ) . Immunophenotypic and idiotypic characterisation of the leukaemic B-cells from patients with prolymphocytic leukaemia: Evidence for a selective expression of immunoglobulin variable region (IGV) gene products . Leukemia Research vol. 17 , ( 8 ) 669 - 676 .
Shokri F, Mageed RA, Robert Maziak B, Talal N, Amos N, Williams BD, Jefferis R ( 1993 ) . Lymphoproliferation in primary sjögren's syndrome. evidence of selective expansion of a b cell subset characterized by the expression of cross‐reactive idiotypes . Arthritis &amp; Rheumatism vol. 36 , ( 8 ) 1128 - 1136 .
SHOKRI F, MAGEED RA, RICHARDSON P, JEFFERIS R ( 1993 ) . Modulation and High Frequency Expression of Autoantibody‐Associated Cross‐Reactive Idiotypes linked to the V<inf>h</inf>I Subgroup in CD5‐Expressing B Lymphocytes from Patients with Chronic Lymphocytic Leukaemia (B‐CLL) . Scandinavian Journal of Immunology vol. 37 , ( 6 ) 673 - 679 .
Scott BB, Sadigh S, Stow M, Mageed RAK, Andrew EM, Maini RN ( 1993 ) . Molecular mechanisms resulting in pathogenic anti-mouse erythrocyte antibodies in New Zealand black mice . Clinical and Experimental Immunology vol. 93 , ( 1 ) 26 - 33 .
Newkirk MM, Rauch J, Mageed RAK, Jefferis R, Posnett DN, Silverman GJ ( 1993 ) . Restricted immunoglobulin variable region gene usage by hybridoma rheumatoid factors from patients with systemic lupus erythematosus and rheumatoid arthritis . Molecular Immunology vol. 30 , ( 3 ) 255 - 263 .
DEANE M, MACKENZIE LE, STEVENSON FK, YOUINOU PY, LYDYARD PM, MAGEED RA ( 1993 ) . The Genetic Basis of Human Vh<sup>4</sup> Gene Family‐Associated Cross‐Reactive Idiotype Expression in CD5<sup>+</sup> and CD5<sup>‐</sup> Cord Blood B‐Lymphocyte Clones . Scandinavian Journal of Immunology vol. 38 , ( 4 ) 348 - 358 .
Mierau R, Gause A, Küppers R, Michels M, Mageed RA, Jefferis R, Genth E ( 1992 ) . A human monoclonal IgA rheumatoid factor using the V<inf>k</inf>IV light chain gene . Rheumatology International vol. 12 , ( 1 ) 23 - 31 .
ABDERRAZIK M, MOYNIER M, JEFFFRIS R, MAGEED RAK, COMBE B, SANY J, BROCHIER J ( 1992 ) . Analysis of Monoclonal Rheumatoid Factors obtained from the B‐Cell Repertoire in Rheumatoid Arthritis . Scandinavian Journal of Immunology vol. 35 , ( 2 ) 149 - 157 .
MACKENZIE LE, MAGEED RA, YOUINOU PY, YUKSEL B, JEFFERIS R, LYDYARD PM ( 1992 ) . Repertoire of CDS<sup>+</sup> and CD5<sup>−</sup> cord blood B cells: specificity and expression of V<inf>H</inf> I and V<inf>H</inf> III associated idiotopes . Clinical &amp; Experimental Immunology vol. 88 , ( 1 ) 107 - 111 .
LYDYARD PM, MacKENZIE LE, YOUINOU PY, DEANE M, JEFFERIS R, MAGEED RA ( 1992 ) . Specificity and Idiotope Expression of IgM Produced by CD5<sup>+</sup> and CD5<sup>−</sup> Cord Blood B‐Cell Clones . Annals of the New York Academy of Sciences vol. 651 , ( 1 ) 527 - 539 .
Macgregor AJ, Carthy D, Mageed R, Ollier WER, Siiman AJ ( 1991 ) . Lack of concordance for rheumatoid factor positivity ue. In a nationwide study of twins with rheumatoid arthritis . Rheumatology (United Kingdom) vol. 30 ,
Mageed RA, MacKenzie LE, Stevenson FK, Yuksel B, Shokri F, Robert Maziak B, Jefferis R, Lydyard PM ( 1991 ) . Selective expression of a V<inf>H</inf>IV subfamily of immunoglobulin genes in human CD5<sup>+</sup> B lymphocytes from cord blood . Journal of Experimental Medicine vol. 174 , ( 1 ) 109 - 113 .
MACKENZIE LE, YOUINOU PY, HICKS R, YUKSEL B, MAGEED RA, LYDYARD PM ( 1991 ) . Auto‐ and Polyreactivity of IgM from CD5<sup>+</sup> and CD5<sup>−</sup> Cord Blood B Cells . Scandinavian Journal of Immunology vol. 33 , ( 3 ) 329 - 335 .
Mageed RA, Kirwan JR, Thompson PW, McCarthy DA, Holborow EJ ( 1991 ) . Characterisation of the size and composition of circulating immune complexes in patients with rheumatoid arthritis . Annals of the Rheumatic Diseases vol. 50 , ( 4 ) 231 - 236 .
Shokri F, Mageed RA, Maziak BR, Jefferis R ( 1991 ) . Expression of V(H)III-associated cross-reactive idiotype on human B lymphocytes. Association with staphylococcal protein A binding and Staphylococcus aureus Cowan I stimulation . Journal of Immunology vol. 146 , ( 3 ) 936 - 940 .
DEACON EM, MATTHEWS JB, POTTS AJC, HAMBURGER J, MAGEED RA, JEFFERIS R ( 1991 ) . Expression of rheumatoid factor associated cross‐reactive idiotopes by glandular B cells in Sjögren's syndrome . Clinical &amp; Experimental Immunology vol. 83 , ( 2 ) 280 - 285 .
MAGEED RA, KIRWAN JR, HOLBOROW EJ ( 1991 ) . Localization of Circulating Immune Complexes from Patients with Rheumatoid Arthritis in Murine Spleen Germinal Centres . Scandinavian Journal of Immunology vol. 34 , ( 3 ) 323 - 331 .
SHOKRI F, MAGEED RAK, KITAS GD, KATSIKIS P, MOUTSOPOULOS HM, JEFFERIS R ( 1991 ) . Quantification of cross‐reactive idiotype‐positive rheumatoid factor produced in autoimmune rheumatic diseases. An indicator of clonality and B cell proliferative mechanisms . Clinical &amp; Experimental Immunology vol. 85 , ( 1 ) 20 - 27 .
Silman AJ, Ollier B, Mageed RA ( 1991 ) . Rheumatoid factor detection in the unaffected first degree relatives in families with multicase rheumatoid arthritis . Journal of Rheumatology vol. 18 , ( 4 ) 512 - 514 .
Mageed RAK, Goodall DM, Jefferis R ( 1990 ) . A highly conserved conformational idiotope on human IgM rheumatoid factor paraproteins of the Wa cross-reactive idiotype family defined by a monoclonal antibody . Rheumatology International vol. 10 , ( 2 ) 57 - 63 .
Brown CMS, Plater-Zyberk C, Mageed RA, Jefferis R, Maini RN ( 1990 ) . Analysis of immunoglobulins secreted by hybridomas derived from rheumatoid synovia . Clinical and Experimental Immunology vol. 80 , ( 3 ) 366 - 372 .
Thompson KM, Randen I, Natvig JB, Mageed RA, Jefferis R, Carson DA, Tighe H, Forre O ( 1990 ) . Human monoclonal rheumatoid factors derived from the polyclonal repertoire of rheumatoid synovial tissue: Incidence of cross‐reactive idiotopes and expression of V<inf>H</inf> and V<inf>ϰ</inf> subgroups . European Journal of Immunology vol. 20 , ( 4 ) 863 - 868 .
Natvig JB, Randen I, Thompson K, Forre O, Mageed RA, Jefferis R, Carson DA, Tighe H et al. ( 1990 ) . Probing of the rheumatoid factor (RF) V gene repertoire in rheumatoid arthritis (RA) by hybridoma clones . Clinical and Experimental Rheumatology vol. 8 , ( SUPPL. 5 ) 75 - 80 .
Shokri F, Mageed RA, Tunn E, Bacon PA, Jefferis R ( 1990 ) . Qualitative and quantitative expression of V(HI) associated cross reactive idiotopes within IgM rheumatoid factor from patients with early synovitis . Annals of the Rheumatic Diseases vol. 49 , ( 3 ) 150 - 154 .
Kondratowicz GM, Symmons DPM, Bacon PA, Mageed RAK, Jones EL ( 1990 ) . Rheumatoid lymphadenopathy: a morphological and immunohistochemical study . Journal of Clinical Pathology vol. 43 , ( 2 ) 106 - 113 .
LYDYARD PM, QUARTEY‐PAPAFIO RP, BRÖKER BM, MACKENZIE L, HAY FC, YOUINOU PY, JEFFERIS R, MAGEED RA ( 1990 ) . The Antibody Repertoire of Early Human B Cells: III. Expression of Cross‐Reactive Idiotopes Characteristic of Certain Rheumatoid Factors and Identifying V<inf>K</inf>III, V<inf>H</inf>I, and V<inf>H</inf>III Gene Family Products . Scandinavian Journal of Immunology vol. 32 , ( 6 ) 709 - 716 .
Crowley JJ, Mageed RA, Silverman GJ, Chen PP, Kozin F, Erger RA, Jefferis R, Carson DA ( 1990 ) . The incidence of a new human cross-reactive idiotype linked to subgroup V<inf>H</inf>III heavy chains . Molecular Immunology vol. 27 , ( 1 ) 87 - 94 .
Shokri F, Mageed RA, Jefferis R, Kitas GD, Katsikis P, Moutsopoulos HM ( 1989 ) . Monoclonal anti-cross-reactive idlotype antibodies as possible probes for lymphoprollferatlon in primary sjögren's syndrome . Rheumatology vol. 28 , ( 5 ) 458 - 459 .
MAGEED R, Venables PJ, Baboonian C, Horsfall AC, Halliday D, Maini RN, Teo CG, Millman G ( 1989 ) . The response of Epstein-Barr virus infection in Sjogren's syndrome . Sjogren's syndrome a model for understanding autoimmunity , Editors: Talal, N , Academic Press Ltd
Venables PJW, Baboonian C, Horsfall AC, Halliday D, Maini RN, Teo CG, Mageed R, Millman G ( 1989 ) . The response to Epstein-Barr virus infection in Sjögren's syndrome . Journal of Autoimmunity vol. 2 , ( 4 ) 439 - 448 .
Jefferis R, Mageed RA ( 1989 ) . The specificity and reactivity of rheumatoid factors with human IgG . Monographs in allergy vol. 26 , 45 - 60 .
Jones VE, Puttick AH, Williamson EA, Mageed RA ( 1988 ) . A new assay uses monoclonal anti-Rh(D) antibodies to determine rheumatoid factor specificity: Reactivity to a monoclonal antibody of the Gm allotype G3m(21) is more frequent in rheumatoid patients negative for G3m(21) . Clinical and Experimental Immunology vol. 71 , ( 3 ) 451 - 458 .
Mageed RA, Carson DA, Jefferis R ( 1988 ) . Analysis of rheumatoid factor autoantibodies in patients with essential mixed cryoglobulinaemia and rheumatoid arthritis . Scandinavian Journal of Rheumatology vol. 17 , ( S75 ) 172 - 178 .
Silverman GJ, Goldfien RD, Chen P, Mageed RA, Jefferis R, Goni F, Frangione B, Fong S et al. ( 1988 ) . Idiotypic and subgroup analysis of human monoclonal rheumatoid factors. Implications for structural and genetic basis of autoantibodies in humans . Journal of Clinical Investigation vol. 82 , ( 2 ) 469 - 475 .
MAGEED RA, CARSON DA, JEFFERIS R ( 1988 ) . Immunogenic and Antigenic Epitopes of Immunoglobulins: XXIII. Idiotypy and Molecular Specificity of Human Rheumatoid Factors: Analysis of Cross‐Reactive Idiotype of Rheumatoid Factor Paraproteins from the Wa Idiotype Group in Relation to Their IgG Subclass Specificity . Scandinavian Journal of Immunology vol. 28 , ( 2 ) 233 - 240 .
Crowley JJ, Goldfien RD, Schrohenloher RE, Spiegelberg HL, Silverman GJ, Mageed RA, Jefferis R, Koopman WJ et al. ( 1988 ) . Incidence of three cross-reactive idiotypes on human rheumatoid factor paraproteins . Journal of Immunology vol. 140 , ( 10 ) 3411 - 3418 .
Jefferis R, Mageed RA ( 1988 ) . The epitope specificity and idiotypy of monoclonal rheumatoid factors . Scandinavian Journal of Rheumatology vol. 17 , ( S75 ) 89 - 92 .
Newkirk MM, Mageed RA, Jefferis R, Chen PP, Donald Capra J ( 1987 ) . Complete amino acid sequences of variable regions of two human IgM rheumatoid factors, bor and kas of the Wa idiotypic family, reveal restricted use of heavy and light chain variable and joining region gene segments . Journal of Experimental Medicine vol. 166 , ( 2 ) 550 - 564 .
Jose SA, Griffiths H, Lunec J, Mageed RA, Jefferis R ( 1987 ) . Immunogenic and antigenic epitopes of immunoglobulin-XX. Denaturation of human IgG3 by free radicals . Molecular Immunology vol. 24 , ( 11 ) 1145 - 1150 .
Mageed RA, Jefferis R ( 1987 ) . Molecular specificity and idiotypy of human rheumatoid factors . Monographs in allergy vol. 22 , 24 - 30 .
Kirk AP, O'Hara BP, Mageed RAK, McMahon MS, McCarthy D, Menashi S, Archer JR, Currey HL ( 1986 ) . Pepsinogen - An immunoglobulin binding artefact in 'collagen' preparations . Clinical and Experimental Immunology vol. 65 , ( 3 ) 671 - 678 .
Mageed RA, Dearlove M, Goodall DM, Jefferis R ( 1986 ) . Immunogenic and antigenic epitopes of immunoglobulins XVII-monoclonal antibodies reactive with common and restricted idiotopes to the heavy chain of human rheumatoid factors . Rheumatology International vol. 6 , ( 4 ) 179 - 183 .
Mageed RA, Walker MR, Jefferis R ( 1986 ) . Restricted light chain subgroup expression on human rheumatoid paraproteins determined by monoclonal antibodies . Immunology vol. 59 , ( 3 ) 473 - 478 .
Bourne JT, Kumar P, Huskisson EC, Mageed R, Unsworth DJ, Wojtulewski JA ( 1985 ) . Arthritis and coeliac disease . Annals of the Rheumatic Diseases vol. 44 , ( 9 ) 592 - 598 .
Church MK, Mageed RAK, Holgale ST ( 1983 ) . Human tonsillar mast cells: Characteristics of histamine secretion and methods of dispersion . International Archives of Allergy and Immunology vol. 72 , ( 2 ) 188 - 190 .