Publications: Prof Michele Bombardieri
Lendrem D, Mitchell S, McMeekin P, Gompels L, Hackett K, Bowman S, Price E, Pease CT et al.
(
2015
)
.
Do the EULAR Sjögren's syndrome outcome measures correlate with health status in primary Sjögren's syndrome?
.
Rheumatology (Oxford)
vol.
54
,
(
4
)
655
-
659
.
Kelly S, Bombardieri M, Humby F, Ng N, Marrelli A, Riahi S, DiCicco M, Mahto A et al.
(
2015
)
.
Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early Rheumatoid Arthritis: an observational study
.
Arthritis Res Ther
vol.
17
,
(
1
)
Kelly S, Bombardieri M, Humby F, Ng N, Marrelli A, Riahi S, DiCicco M, Mahto A et al.
(
2015
)
.
Angiogenic gene expression and vascular density are reflected in ultrasonographic features of synovitis in early rheumatoid arthritis: an observational study
.
Arthritis Research & Therapy
vol.
17
,
(
1
)
Kelly S, Humby F, Filer A, Ng N, Di Cicco M, Hands RE, Rocher V, Bombardieri M et al.
(
2015
)
.
Ultrasound-guided synovial biopsy: a safe, well-tolerated and reliable technique for obtaining high-quality synovial tissue from both large and small joints in early arthritis patients
.
Ann Rheum Dis
vol.
74
,
(
3
)
611
-
617
.
Nayar S, Campos J, Cloake T, Bowman S, Bombardieri M, Pitzalis C, Luther S, Buckley C et al.
(
2015
)
.
IL22 Regulates Autoantibody Production by Inducing Lymphoid Chemokine Expression in Tertiary Lymphoid Organs
.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
.
vol.
81
,
425
-
425
.
Murray-Brown W, Carlotti E, Floyd J, Sutcliffe N, Tappuni A, Vartoukian S, Fortune F, Mehr R et al.
(
2015
)
.
Next-Generation Sequencing Demonstrates Dynamic Recirculation of B Cell Clones in Ectopic Lymphoid Structures of Sjogren's Syndrome
.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
.
vol.
81
,
401
-
402
.
Astorri E, Croia C, Picarelli G, Sutcliffe N, Tappuni A, Bombardieri M, Priori R
(
2015
)
.
Routine Investigations for Circulating IgG4 and/or IgG4+Salivary Gland Histopathology Fail to Reveal Undiagnosed Cases of IgG4 Related Disease in Sicca Patients not Fulfilling the Diagnosis of Sjogren's Syndrome
.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
.
vol.
81
,
341
-
341
.
Astorri E, Nerviani A, Bombardieri M, Pitzalis C
(
2015
)
.
Towards a stratified targeted approach with biologic treatments in rheumatoid arthritis: role of synovial pathobiology
.
Current Pharmaceutical Design
vol.
21
,
(
17
)
2216
-
2224
.
Fisher B, Jonsson R, Daniels T, Bombardieri M, Morgan P, Brown R, Bowman S, Barone F
(
2015
)
.
Towards the Standardisation of Salivary Gland Histopathology for Use in the Diagnosis of Primary Sjogren's Syndrome and in Clinical Trials. Report of a Preliminary Workshop
.
SCANDINAVIAN JOURNAL OF IMMUNOLOGY
.
vol.
81
,
333
-
334
.
VARTOUKIAN SR, Tilakaratne W, Seoudi N, Bombardieri M, Bergmeier L, Tappuni A, Fortune F
(
2014
)
.
Dysregulation of the SOCS3-STAT3 pathway in the aetio-pathogenesis of Sjögren’s syndrome
.
Clinical and Experimental Immunology
vol.
177
,
(
3
)
618
-
629
.
Croia C, Astorri E, Murray-Brown W, Willis A, Brokstad KA, Sutcliffe N, Piper K, Jonsson R et al.
(
2014
)
.
Implication of Epstein-Barr virus infection in disease-specific autoreactive B cell activation in ectopic lymphoid structures of Sjögren's syndrome
.
Arthritis Rheumatol
vol.
66
,
(
9
)
2545
-
2557
.
Pitzalis C, Jones GW, Bombardieri M, Jones SA
(
2014
)
.
Ectopic lymphoid-like structures in infection, cancer and autoimmunity
.
Nat Rev Immunol
vol.
14
,
(
7
)
447
-
462
.
Ng N, Kelly S, Humby F, DiCicco M, Rocher V, Hands R, Bombardieri M, Pitzalis C
(
2014
)
.
OP0054 Ultrasound Synovitis Reflects Synovial Inflammation at A Histopathological Level
.
Annals of the Rheumatic Diseases
.
vol.
73
,
Corsiero E, Carlotti E, Pratesi F, Wardemann H, Robinson W, Migliorini P, Pitzalis C, Bombardieri M
(
2014
)
.
OP0266 Monoclonal Antibodies Derived from Single CD19+ Synovial B Cells of RA Patients with Tertiary Lymphoid Structures Display Preferential Immunoreactivity towards Citrullinated Proteins of Nets
.
Annals of the Rheumatic Diseases
.
vol.
73
,
Di Cicco M, Kelly S, Humby F, Ng N, Nerviani A, Rocher V, Hands R, Bombardieri M et al.
(
2014
)
.
SAT0048 Synovial Lymphocytic Aggregates Predict Clinical Response to Certolizumab Pegol in Rheumatoid Arthritis (Clinical and Pathological Response to Certolizumab-Pegol (Clip-Cert) Study)
.
Annals of the Rheumatic Diseases
.
vol.
73
,
Lucchesi D, Pitzalis C, Bombardieri M
(
2014
)
.
EBV and other viruses as triggers of tertiary lymphoid structures in primary Sjögren's syndrome
.
Expert Rev Clin Immunol
vol.
10
,
(
4
)
445
-
455
.
Corsiero E, Carlotti E, Wardemann H, Robinson W, Migliorini P, Pratesi F, Pitzalis C, Bombardieri M
(
2014
)
.
A1.31 Monoclonal antibodies from CD19+ synovial B cells of RA patients with tertiary lymphoid structures display a strong immunoreactivity towards citrullinated histones from neutrophils NETs
.
Annals of the Rheumatic Diseases
.
vol.
73
,
Corsiero E, Bombardieri M, Carlotti E, Pratesi F, Robinson W, Migliorini P, Pitzalis C
(
2014
)
.
Citrullinated histones from neutrophil extracellular traps (NETs) fuel ectopic germinal centre responses and ACPA production in rheumatoid joints
.
IMMUNOLOGY
vol.
143
,
43
-
43
.
Pontarini E, Lucchesi D, Bombardieri M, Mavilio D
(
2014
)
.
Recruitment and activation of NK cells regulates early immune responses to viral infection in the salivary glands of an inducible murine model of Sjogren-like disease
.
IMMUNOLOGY
vol.
143
,
93
-
93
.
Brown S, Coy NN, Pitzalis C, Emery P, Pavitt S, Gray J, Hulme C, Hall F et al.
(
2014
)
.
The TRACTISS Protocol: a randomised double blind placebo controlled clinical TRial of Anti-B-Cell Therapy In patients with primary Sjogren's Syndrome
.
BMC MUSCULOSKELETAL DISORDERS
vol.
15
,
Article
ARTN 21
,
Croia C, Serafini B, Bombardieri M, Kelly S, Humby F, Severa M, Rizzo F, Coccia EM et al.
(
2013
)
.
Epstein-Barr virus persistence and infection of autoreactive plasma cells in synovial lymphoid structures in rheumatoid arthritis
.
Ann Rheum Dis
vol.
72
,
(
9
)
1559
-
1568
.
Strollo R, Ponchel F, Malmström V, Rizzo P, Bombardieri M, Wenham CY, Landy R, Perret D et al.
(
2013
)
.
Autoantibodies to posttranslationally modified type II collagen as potential biomarkers for rheumatoid arthritis
.
Arthritis Rheum
vol.
65
,
(
7
)
1702
-
1712
.
Lendrem D, Mitchell S, McMeekin P, Bowman S, Price E, Pease CT, Emery P, Andrews J et al.
(
2013
)
.
Health-related utility values of patients with primary Sjögren's syndrome and its predictors
.
Annals of the Rheumatic Diseases
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M
(
2013
)
.
ACCUMULATION OF CIRCULATING AUTOREACTIVE NAIVE B CELLS REVEALS DEFECTS OF EARLY B-CELL TOLERANCE CHECKPOINTS IN PATIENTS WITH SJOGREN'S SYNDROME
.
RHEUMATOLOGY
.
vol.
52
,
159
-
159
.
Ng N, Humby F, Bombardieri M, Kelly S, Di Cicco M, Dadoun S, Hands R, Rocher V et al.
(
2013
)
.
CLINICAL, IMAGING AND HISTOLOGICAL CHARACTERISTICS OF PATIENTS WITH RHEUMATOID ARTHRITIS AT DIFFERENT STAGES OF DISEASE PROGRESSION
.
RHEUMATOLOGY
.
vol.
52
,
71
-
71
.
Kam NW, Filter A, Buckley C, Pitzalis C, Bombardieri M
(
2013
)
.
MEMBRANE-BOUND AND SOLUBLE BAFF EXPRESSION BY HUMAN RHEUMATOID FIBROBLAST-LIKE SYNOVIOCYTES IN RESPONSE TO TLR STIMULATION
.
RHEUMATOLOGY
.
vol.
52
,
80
-
80
.
Di Cicco M, Humby F, Kelly S, Ng N, Hands R, Dadoun S, Buckley C, McInnes IB et al.
(
2013
)
.
SYNOVIAL LYMPHOCYTE AGGREGATES IN EARLY INFLAMMATORY ARTHRITIS: CORRELATION WITH DIAGNOSIS, DISEASE ACTIVITY AND ANTIBODY STATUS
.
RHEUMATOLOGY
.
vol.
52
,
29
-
29
.
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M
(
2013
)
.
ACCUMULATION OF CIRCULATING AUTOREACTIVE NAIVE B CELLS REVEAL DEFECTS OF EARLY B CELL TOLERANCE CHECKPOINTS IN PATIENTS WITH SJOGREN'S SYNDROME
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
72
,
792
-
792
.
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M
(
2013
)
.
Accumulation of Circulating Autoreactive Naive B Cells Reveal Defects of Early B Cell Tolerance Checkpoints in Patients with Sjogren's Syndrome
.
ANNALS OF THE RHEUMATIC DISEASES
.
vol.
72
,
A30
-
A31
.
Patel HB, Bombardieri M, Pitzalis C, Perretti M
(
2013
)
.
Activation of Melanocortin Receptor 3 as a new strategy to control experimental and rheumatoid arthritis
.
FASEB JOURNAL
.
vol.
27
,
Croia C, Serafini B, Tappuni A, Aloisi F, Sutcliffe N, Pitzalis C, Bombardieri M
(
2013
)
.
ECTOPIC LYMPHOID STRUCTURES SUPPORT EPSTEIN-BARR VIRUS PERSISTENCE AND AUTOREACTIVE PLASMA CELL INFECTION IN SJOGREN'S SYNDROME SALIVARY GLANDS
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
72
,
462
-
462
.
Ng W-F, Lendrem D, Mitchell S, Bowman S, Price E, Pease C, Emery P, Andrews J et al.
(
2013
)
.
EVALUATING HEALTH STATUS OF 620 PATIENTS WITH PRIMARY SJOGREN'S SYNDROME USING EQ-5D
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
71
,
466
-
466
.
Astorri E, Scrivo R, Bombardieri M, Picarelli G, Pecorella I, Porzia A, Valesini G, Priori R
(
2013
)
.
EXPRESSION OF FRACTALKINE IN SJOGREN'S SYNDROME PATIENTS: CELLULAR AND MOLECULAR CHARACTERIZATION OF CX3CL1 AND CX3CR1 IN SERA AND SALIVARY GLANDS
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
72
,
78
-
78
.
Ng W-F, Mitchell S, Lendrem D, Bowman S, Price E, Pease C, Emery P, Andrews J et al.
(
2013
)
.
HOW GOOD ARE THE EULAR SJOGREN'S SYNDROME DISEASE ACTIVITY INDEX (ESSDAI), AND EULAR SJOGREN'S SYNDROME PATIENTS REPORTED INDEX (ESSPRI) IN PREDICTING HEALTH STATUS IN PRIMARY SJOGREN'S SYNDROME?
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
71
,
553
-
554
.
Lucchesi D, Bombardieri M, Barone F, Nayar S, Proctor G, Buckley CD, Pitzalis C
(
2013
)
.
INDUCIBLE TERTIARY LYMPHOID STRUCTURES AND AUTOIMMUNITY IN A NOVEL MODEL OF SIALOADENITIS IN WILD-TYPE MICE
.
ANNALS OF THE RHEUMATIC DISEASES
.
vol.
72
,
A42
-
A42
.
Jones GW, Bombardieri M, Greenhill CJ, McLeod L, Rocher V, Williams AS, Pitzalis C, Jenkins BJ et al.
(
2013
)
.
Interleukin-27 as a novel antagonist of ectopic lymphoid-like structure development in early inflammatory arthritis
.
CYTOKINE
.
vol.
63
,
274
-
274
.
Murray-Brown W, Croia C, Sutcliffe N, Tappuni A, Vartoukian S, Fortune F, Pitzalis C, Bombardieri M
(
2013
)
.
LESIONAL IL-21 EXPRESSION CORRELATES WITH FUNCTIONAL GERMINAL CENTER FORMATION AND T FOLLICULAR HELPER CELL INFILTRATION IN THE SALIVARY GLANDS OF SJOGREN'S SYNDROME
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
72
,
77
-
77
.
Ng W-F, Miller A, Bowman S, Price E, Kitas G, Pease C, Emery P, Lanyon P et al.
(
2013
)
.
LEVEL OF PHYSICAL ACTIVITY IN PRIMARY SJOGREN'S SYNDROME AND ITS PREDICTORS
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
72
,
483
-
484
.
Murray-Brown W, Croia C, Sutcliffe N, Tappuni A, Pitzalis C, Bombardieri M
(
2013
)
.
Lesional Intereukin-21 Expression Correlates With Functional Germinal Center Formation and T Follicular Helper Cell Infiltration In The Salivary Glands Of Sjogren's Syndrome
.
ARTHRITIS AND RHEUMATISM
.
vol.
65
,
S634
-
S634
.
Bombardieri M, Rocher V, Mittereder N, Carlesso G, Herbst R, Sleeman M, Pitzalis C
(
2013
)
.
MAVRILIMUMAB REDUCES PRO-INFLAMMATORY CYTOKINES AND CD68 POSITIVE MACROPHAGES IN SYNOVIAL EXPLANTS FROM RHEUMATOID ARTHRITIS SUBJECTS ENGRAFTED INTO SCID/BEIGE MICE
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
72
,
156
-
157
.
Ng N, Humby F, Kelly S, Di Cicco M, Dadoun S, Bombardieri M, Hands R, Rocher V et al.
(
2013
)
.
RHEUMATOID ARTHRITIS PATIENT CHARACTERISTICS AT DIFFERENT THERAPEUTIC TIMEPOINTS
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
72
,
862
-
862
.
Corsiero E, Bombardieri M, Carlotti E, Wardemann H, Robinson WH, Pitzalis C
(
2013
)
.
Recombinant Monoclonal Antibodies Derived From Single CD19+Synovial B Cells Of RA Patients With Tertiary Lymphoid Structures Display a Strong Immunoreactivity Towards Citrullinated Histones
.
ARTHRITIS AND RHEUMATISM
.
vol.
65
,
S1127
-
S1128
.
Tarn J, Mitchell S, Bowman S, Price E, Pease C, Sutcliffe N, Emery P, Andrews J et al.
(
2013
)
.
SERUM CYTOKINE AND CHEMOKINE PROFILING IN PRIMARY SJOGREN'S SYNDROME
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
71
,
527
-
528
.
Di Cicco M, Dadoun S, Humby F, Kelly S, Ng N, Hands RE, Buckley C, McInnes I et al.
(
2013
)
.
SYNOVIAL ECTOPIC LYMPHOID-LIKE STRUCTURES ARE ASSOCIATED WITH DIAGNOSIS OF RHEUMATOID ARTHRITIS, DISEASE ACTIVITY AND ANTIBODY STATUS IN EARLY ARTHRITIS PATIENTS
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
72
,
192
-
192
.
Croia C, Serafini B, Bombardieri M, Kelly S, Humby F, Severa M, Rizzo F, Coccia EM et al.
(
2013
)
.
SYNOVIAL LYMPHOID STRUCTURES SUPPORT EPSTEIN-BARR VIRUS PERSISTENCE AND AUTOREACTIVE PLASMA CELL INFECTION IN RHEUMATOID ARTHRITIS
.
ANNALS OF THE RHEUMATIC DISEASES
.
vol.
72
,
A43
-
A44
.
Deidda S, Humby F, Kelly S, Di Cicco M, Ng N, Hands R, Bombardieri M, Pitzalis C
(
2013
)
.
SYNOVIAL SUBLINING MACROPHAGES: A SENSITIVE BIOMARKER FOR RESPONSE TO TREATMENT IN EARLY RA PATIENTS
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
72
,
583
-
584
.
Kam YNW, Filer A, Buckley CD, Pitzalis C, Bombardieri M
(
2013
)
.
Secretory Leukocyte Protease Inhibitor Released By Rheumatoid Synovial Fibroblasts Exerts a Negative Control Of BAFF-Dependent B Cell Activation In Vitro and In Vivo In The Collagen-Induced and Chimeric RA/SCID Arthritis Models
.
ARTHRITIS AND RHEUMATISM
.
vol.
65
,
S1029
-
S1029
.
Di Cicco M, Kelly S, Humby F, Ng N, Dadoun S, Hands R, Rocher V, Nerviani A et al.
(
2013
)
.
Synovial Ectopic Lymphoneogenesis Predicts Clinical Response To Certolizumab Pegol In Patients With Rheumatoid Arthritis
.
ARTHRITIS AND RHEUMATISM
.
vol.
65
,
S556
-
S556
.
Ciccia F, Rizzo A, Accardo-Palumbo A, Giardina A, Bombardieri M, Guggino G, Taverna S, Leo GD et al.
(
2012
)
.
Increased expression of interleukin-32 in the inflamed ileum of ankylosing spondylitis patients
.
Rheumatology (Oxford)
vol.
51
,
(
11
)
1966
-
1972
.
Bombardieri M, Barone F, Lucchesi D, Nayar S, van den Berg WB, Proctor G, Buckley CD, Pitzalis C
(
2012
)
.
Inducible tertiary lymphoid structures, autoimmunity, and exocrine dysfunction in a novel model of salivary gland inflammation in C57BL/6 mice
.
J Immunol
vol.
189
,
(
7
)
3767
-
3776
.
Croia C, Bombardieri M, Francesca A, Serafini B, Humby F, Kelly S, Migliorini P, Pitzalis C
(
2012
)
.
ANTI-VCA AND EBNA1 ANTIBODIES ARE PRODUCED IN THE RHEUMATOID SYNOVIUM IN THE PRESENCE OF ECTOPIC LYMPHOID STRUCTURES AND CORRELATE WITH ACPA PRODUCTION
.
RHEUMATOLOGY
.
vol.
51
,
43
-
43
.
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M
(
2012
)
.
Accumulation of circulating autoreactive naive B cells reveal defects of early B cell tolerance checkpoints in patients with Sjogren's syndrome
.
IMMUNOLOGY
.
vol.
137
,
327
-
327
.
Newton JL, Frith J, Powell D, Hackett K, Wilton K, Bowman S, Price E, Pease C et al.
(
2012
)
.
Autonomic symptoms are common and are associated with overall symptom burden and disease activity in primary Sjogren's syndrome
.
ANNALS OF THE RHEUMATIC DISEASES
vol.
71
,
(
12
)
1973
-
1979
.
Nayar S, Cloake T, Bombardieri M, Pitzalis C, Buckley C, Barone F
(
2012
)
.
ECTOPIC LYMPHONEOGENESIS IN A NOVEL MURINE MODEL OF SALIVARY GLANDS SIALOADENITIS IS CHARACTERIZED BY ASYNCHRONY IN THE LYMPHANGIOGENETIC AND ANGIOGENETIC PROGRAM
.
RHEUMATOLOGY
.
vol.
51
,
143
-
144
.
Lendrem D, Mitchell S, Bowman S, Price E, Pease CT, Emery P, Andrews J, Bombardieri M et al.
(
2012
)
.
EVALUATING HEALTH STATUS OF 620 PATIENTS WITH PRIMARY SJOGREN'S SYNDROME USING EQ-5D
.
RHEUMATOLOGY
.
vol.
51
,
171
-
171
.
Lendrem D, Mitchell S, Bowman S, Price E, Pease CT, Emery P, Andrews J, Bombardieri M et al.
(
2012
)
.
HOW GOOD ARE THE EULAR SJOGREN'S SYNDROME DISEASE ACTIVITY INDEX, AND EULAR SJOGREN'S SYNDROME PATIENTS REPORTED INDEX IN PREDICTING HEALTH STATUS IN PRIMARY SJOGREN'S SYNDROME?
.
RHEUMATOLOGY
.
vol.
51
,
176
-
176
.
Jones GW, Greenhill CJ, Williams AS, Nowell MA, Bombardieri M, Pitzalis C, Jenkins BJ, Jones SA
(
2012
)
.
IL-27 control of ectopic lymphoid structures in inflammatory arthritis
.
IMMUNOLOGY
.
vol.
137
,
44
-
44
.
Lucchesi D, Bombardieri M, Barone F, Nayar S, Proctor G, Buckley CD, Pitzalis C
(
2012
)
.
Inducible tertiary lymphoid structures formation in a novel model of sialoadenitis in wild-type mice is preceded by ectopic expression of lymphoid chemokines
.
IMMUNOLOGY
.
vol.
137
,
189
-
189
.
Murray-Brown W, Croia C, Sutcliffe N, Tappuni A, Vartoukian S, Fortune F, Pitzalis C, Bombardieri M
(
2012
)
.
Lesional IL-21 expression correlates with functional germinal center formation and T follicular helper cell infiltration in the salivary glands of Sjogren's syndrome
.
IMMUNOLOGY
.
vol.
137
,
491
-
491
.
Murray-Brown W, Priori R, Tappuni T, Vartoukian S, Seoudi N, Picarelli G, Fortune F, Valesini G et al.
(
2012
)
.
MONOCYTE-DERIVED IL-32 EXPRESSION CORRELATES WITH THE LEVEL OF INFLAMMATION IN SALIVARY GLANDS OF SJOGREN'S SYNDROME
.
RHEUMATOLOGY
.
vol.
51
,
176
-
176
.
Kam NW, Filer A, Buckley C, Bombardieri M, Pitzalis C
(
2012
)
.
Membrane-bound and soluble BAFF expression by human rheumatoid fibroblast-like synoviocytes in response to TLR stimulation
.
IMMUNOLOGY
.
vol.
137
,
583
-
584
.
Vila J, Mitchell S, Bowman S, Price E, Pease CT, Emery P, Andrews J, Bombardieri M et al.
(
2012
)
.
THE CLINICAL RELEVANCE OF ANTI-RO52 AND ANTI-RO60 IN PATIENTS IN THE UNITED KINGDOM PRIMARY SJOGREN'S SYNDROME REGISTRY (UKPSSR)
.
RHEUMATOLOGY
.
vol.
51
,
35
-
35
.
DiCicco M, Humby F, Kelly S, Hands R, Buckley C, McInnes I, Taylor P, Bombardieri M et al.
(
2012
)
.
THE PATHOBIOLOGY OF EARLY ARTHRITIS COHORT: A PRELIMINARY ANALYSIS CORRELATING HISTOMORPHOLOGY AND DISEASE ACTIVITY
.
RHEUMATOLOGY
.
vol.
51
,
149
-
149
.
Marrelli A, Bombardieri M, Kelly S, Cipriani P, Giacomelli R, Pitzalis C
(
2011
)
.
DIGITAL IMAGE ANALYSIS FOR THE EVALUATION OF BLOOD VESSEL DENSITY IN RHEUMATOID SYNOVIUM: CORRELATION WITH QUANTITATIVE REAL-TIME PCR EXPRESSION OF ENDOTHELIAL ANTIGEN AND ANGIOGENIC GROWTH FACTORS
.
RHEUMATOLOGY
.
vol.
50
,
75
-
75
.
Croia C, Serafini B, Bombardieri M, Kelly S, Coccia EM, Severa M, Francesca A, Pitzalis C
(
2011
)
.
EBV INFECTION IN THE RHEUMATOID ARTHRITIS SYNOVIUM: RELATIONSHIP TO ECTOPIC LYMPHOID STRUCTURES AND CD8 T CELL ACTIVATION
.
RHEUMATOLOGY
.
vol.
50
,
75
-
75
.
Bombardieri M
(
2011
)
.
HOW WILL B-CELL BASIC SCIENCE RESEARCH DRIVE TREATMENT IN SJOGREN'S SYNDROME?
.
RHEUMATOLOGY
.
vol.
50
,
12
-
13
.
Astorri E, Bombardieri M, Gabba S, Peakman M, Pozzilli P, Pitzalis C
(
2011
)
.
EVOLUTION OF ECTOPIC LYMPHOID NEOGENESIS AND IN SITU AUTOANTIBODIES PRODUCTION IN AUTOIMMUNE DIABETIC NOD MICE: CELLULAR AND MOLECULAR CHARACTERISATION OF TERTIARY LYMPHOID STRUCTURES IN PANCREATIC ISLETS
.
ANNALS OF THE RHEUMATIC DISEASES
.
vol.
70
,
Bombardieri M, Kam YNW, Filer A, Buckley CD, Pitzalis C
(
2011
)
.
Aberrant Basal and TLR-Stimulated Expression of TSLP in Rheumatoid Synovial Fibroblasts
.
ARTHRITIS AND RHEUMATISM
.
vol.
63
,
S140
-
S140
.
Kam NW, Bombardieri M, Filer A, Buckley C, Pitzalis C
(
2011
)
.
Aberrant basal and TLR-stimulated expression of TSLP in rheumatoid synovial fibroblasts
.
IMMUNOLOGY
.
vol.
135
,
125
-
125
.
Corsiero E, Sutcliffe N, Wardemann H, Pitzalis C, Bombardieri M
(
2011
)
.
Analysis of recombinant monoclonal antibodies from single B cells reveals early defects of B cell tolerance checkpoints in patients with Sjogren's syndrome
.
IMMUNOLOGY
.
vol.
135
,
72
-
72
.
Croia C, Bombardieri M, Serafini B, Coccia EM, Severa M, Kelly S, Aloisi F, Pitzalis C
(
2011
)
.
EBV Infection In the Rheumatoid Synovium: Relationship with Ectopic Lymphoid Structures, In Situ Autoantobody Production and CD8 T Cell Activation
.
ARTHRITIS AND RHEUMATISM
.
vol.
63
,
S140
-
S140
.
Nayar S, Barone F, Choy P, Chang M-M, Bombardieri M, Lucchesi D, Pitzalis C, Buckley C
(
2011
)
.
Ectopic lymphoneogenesis in a novel murine model of salivary glands sialoadenitis is characterized by asynchrony in the lymphangiogenetic and angiogenetic program
.
IMMUNOLOGY
.
vol.
135
,
49
-
49
.
Bombardieri M, Lucchesi D, Barone F, Nayar S, Proctor G, Buckley CD, Pitzalis C
(
2011
)
.
Inducible functional tertiary lymphoid structures, autoimmunity and exocrine dysfunction in wild-type mouse salivary glands via local adenoviral delivery
.
IMMUNOLOGY
.
vol.
135
,
167
-
167
.
Bugatti S, Manzo A, Bombardieri M, Vitolo B, Humby F, Kelly S, Montecucco C, Pitzalis C
(
2011
)
.
Synovial Tissue Heterogeneity and Peripheral Blood Biomarkers
.
CURRENT RHEUMATOLOGY REPORTS
vol.
13
,
(
5
)
440
-
448
.
Patel HB, Bombardieri M, Sampaio ALF, D'Acquisto F, Gray M, Grieco P, Getting SJ, Pitzalis C et al.
(
2010
)
.
Anti-inflammatory and antiosteoclastogenesis properties of endogenous melanocortin receptor type 3 in experimental arthritis
.
FASEB J
vol.
24
,
(
12
)
4835
-
4843
.
Corsiero E, Bombardieri M, Humby F, Manzo A, Kelly S, Pitzalis C
(
2010
)
.
Characterization of inter follicular large B cells, a new subpopulation of B lymphocytes, in tertiary lymphoid organs in rheumatic autoimmune diseases
.
IMMUNOLOGY
.
vol.
131
,
33
-
33
.
Astorri E, Guglielmi C, Bombardieri M, Alessandri C, Buzzetti R, Maggi D, Valesini G, Pitzalis C et al.
(
2010
)
.
Circulating Reg1α proteins and autoantibodies to Reg1α proteins as biomarkers of β-cell regeneration and damage in type 1 diabetes
.
Horm Metab Res
vol.
42
,
(
13
)
955
-
960
.
Croia C, Serafini B, Bombardieri M, Kelly S, Coccia EM, Severa M, Aloisi F, Pitzalis C
(
2010
)
.
EBV infection in the rheumatoid arthritis synovium: relationship to tertiary lymphoid structures and CD8 T cell activation
.
IMMUNOLOGY
.
vol.
131
,
124
-
124
.
Astorri E, Bombardieri M, Gabba S, Peakman M, Pozzilli P, Pitzalis C
(
2010
)
.
Evolution of ectopic lymphoid neogenesis and in-situ autoantibodies production in autoimmune diabetic NOD mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic islet
.
IMMUNOLOGY
.
vol.
131
,
63
-
63
.
Ciccia F, Accardo-Palumbo A, Giardina A, Di Maggio P, Principato A, Bombardieri M, Rizzo A, Alessandro R et al.
(
2010
)
.
Expansion of Intestinal CD4+CD25(high) Treg Cells in Patients With Ankylosing Spondylitis A Putative Role for Interleukin-10 in Preventing Intestinal Th17 Response
.
ARTHRITIS RHEUM-US
vol.
62
,
(
12
)
3625
-
3634
.
Lucchesi D, Astorri E, Bombardieri M, Corsiero E, Barone F, Proctor G, Pitzalis C
(
2010
)
.
Molecular and cellular evolution of functional tertiary lymphoid structures in salivary glands of NOD mice
.
IMMUNOLOGY
.
vol.
131
,
59
-
59
.
Kam NW, Bombardieri M, Brentano F, Choi K, Kyburz D, Gay S, Mclnnes IB, Pitzalis C
(
2010
)
.
Rheumatoid synovial fibroblasts support AID expression and Ig class-switching in B cells via a Baff-dependent TLR3-stimulated pathway
.
IMMUNOLOGY
.
vol.
131
,
71
-
71
.
Ciccia F, Bombardieri M, Rizzo A, Principato A, Giardina AR, Raiata F, Peralta S, Ferrante A et al.
(
2010
)
.
Over-expression of paneth cell-derived anti-microbial peptides in the gut of patients with ankylosing spondylitis and subclinical intestinal inflammation
.
Rheumatology (Oxford)
vol.
49
,
(
11
)
2076
-
2083
.
Astorri E, Bombardieri M, Gabba S, Peakman M, Pozzilli P, Pitzalis C
(
2010
)
.
Evolution of ectopic lymphoid neogenesis and in situ autoantibody production in autoimmune nonobese diabetic mice: cellular and molecular characterization of tertiary lymphoid structures in pancreatic islets
.
J Immunol
vol.
185
,
(
6
)
3359
-
3368
.
Astorri E, Bombardieri M, Corsiero E, Gabba S, Barone F, Proctor G, Pitzalis C
(
2010
)
.
MOLECULAR AND CELLULAR EVOLUTION OF FUNCTIONAL TERTIARY LYMPHOID STRUCTURES IN SALIVARY GLANDS OF NOD MICE
.
RHEUMATOLOGY
.
vol.
49
,
I28
-
I28
.
Bombardieri M, Kam YNW, Brentano F, Choi K, Kyburz D, Gay S, McInnes IB, Pitzalis C
(
2010
)
.
RHEUMATOID SYNOVIAL FIBROBLASTS SUPPORT AID EXPRESSION AND IG CLASS-SWITCHING IN B CELLS VIA A BAFF-DEPENDENT TLR3-STIMULATED PATHWAY
.
RHEUMATOLOGY
.
vol.
49
,
I26
-
I27
.
Swales C, Mahoney DJ, Athanasou NA, Bombardieri M, Pitzalis C, Sharif O, Day AJ, Milner CM et al.
(
2010
)
.
TSG-6: AN AUTOCRINE REGULATOR OF INFLAMMATORY JOINT DISEASE?
.
RHEUMATOLOGY
.
vol.
49
,
I27
-
I27
.
Bombardieri M, Astorri E, Corsiero E, Gabba S, Barone F, Proctor G, Pitzalis C
(
2010
)
.
MOLECULAR AND CELLULAR EVOLUTION OF FUNCTIONAL TERTIARY LYMPHOID STRUCTURES IN SALIVARY GLANDS OF NOD MICE
.
ANNALS OF THE RHEUMATIC DISEASES
.
vol.
69
,
Manzo A, Bombardieri M, Humby F, Pitzalis C
(
2010
)
.
Secondary and ectopic lymphoid tissue responses in rheumatoid arthritis: from inflammation to autoimmunity and tissue damage/remodeling
.
IMMUNOL REV
vol.
233
,
267
-
285
.
Patel HB, Bombardieri M, Pitzalis C, Perretti M
(
2009
)
.
Activation of melanocortin receptor type 3 as a new strategy to control experimental and rheumatoid arthritis
.
EUR J CLIN INVEST
vol.
39
,
29
-
29
.
Bombardieri M, Ciccia F, Principato A, Tripodo C, Peralta S, Triolo G, Pitzalis C
(
2009
)
.
IL-23 OVEREXPRESSION AS IMMUNOLOGICAL SIGNATURE OF SUBCLINICAL INTESTINAL INFLAMMATION IN ANKYLOSING SPONDYLITIS
.
RHEUMATOLOGY
.
vol.
48
,
I6
-
I6
.
Humby F, Bombardieri M, Manzo A, Kelly S, Blades MC, Kirkham B, Spencer J, Pitzalis C
(
2009
)
.
Ectopic lymphoid structures support ongoing production of class-switched autoantibodies in rheumatoid synovium
.
PLoS Med
vol.
6
,
(
1
)
Guglielmi C, Astorri E, Portuesi R, Bombardieri M, Valorani M, Pozzilli P
(
2008
)
.
A diet rich in protein and poor in starch with reduced food intake prevents diabetes in the NOD moose: the significance of Reg gene expression in the pancreas
.
DIABETOLOGIA
vol.
51
,
S229
-
S229
.
Humby F, Bombardieri M, Antonio M, Blades M, Bruce K, Spencer J, Pitzalis C
(
2008
)
.
Ectopic lymphoid structures expressing AID drive self sustained in situ prodction of autoantibodies in rheumatoid synovium
.
ARTHRITIS AND RHEUMATISM
.
vol.
58
,
S633
-
S634
.
Bombardieri M, Barone F, Humby F, Morgan P, Challacombe S, Spencer J, Pitzalis C
(
2008
)
.
Activation-induced cytidine deaminase expression supports functionality of ectopic lymphoid neogenesis in patients with and animal models of Sjogren's syndrome
.
RHEUMATOLOGY
.
vol.
47
,
II85
-
II85
.
Humby F, Bombardieri M, Manzo A, Blades M, Kirkham B, Spencer J, Pitzalis C
(
2008
)
.
Activation-induced cytidine deaminase supports self sustained autoantibody production within RA synovium
.
RHEUMATOLOGY
.
vol.
47
,
II59
-
II59
.
Astorri E, Bombardieri M, Guglielmi C, Pitzalis C, Pozzilli P
(
2008
)
.
Beta cell regeneration in type 1 diabetes: the role of Reg genes in NOD mice
.
DIABETOLOGIA
vol.
51
,
S186
-
S186
.
Bombardieri M, Barone F, Humby F, Kelly S, McGurk M, Morgan P, Challacombe S, De Vita S et al.
(
2007
)
.
Activation-induced cytidine deaminase expression in follicular dendritic cell networks and interfollicular large B cells supports functionality of ectopic lymphoid neogenesis in autoimmune sialoadenitis and MALT lymphoma in Sjögren's syndrome
.
J Immunol
vol.
179
,
(
7
)
4929
-
4938
.
Bombardieri M, McInnes IB, Pitzalis C
(
2006
)
.
Interleukin-18 as a potential therapeutic target in chronic autoimmune/inflammatory conditions
.
Expert Opinion on Biological Therapy
vol.
7
,
(
1
)
31
-
40
.
Bombardieri M, Barone F, Carlucci F, Proctor G, van de Loo FA, van den Berg WB, Botto M, Valesini G et al.
(
2006
)
.
The IL-18/IL-18R axis is significantly up-regulated in submandibular glands in the nod mouse model of Sjogren's syndrome and is associated with an ongoing TH1-mediated inflammation
.
RHEUMATOLOGY
.
vol.
45
,
I156
-
I156
.