Publications: Prof David Baker
Allen-Philbey K, Stephenson S, Doody G, MacDougall A, Aboulwafaali M, Ammoscato F, Andrews M, Gnanapavan S et al.
(
2024
)
.
Effects of cladribine on intrathecal and peripheral B and plasma cells
.
Clinical & Experimental Immunology
Ammoscato F, Wafa M, Skonieczna J, Bestwick J, Monero R, Andrews M, De Trane S, Holden D et al.
(
2024
)
.
Cladribine tablets in relapsing-remitting multiple sclerosis preferentially target B-cells
.
Clinical Immunology
vol.
269
,
Pingitore V, Pancholi J, Hornsby TW, Warne J, Pryce G, McCormick LJ, Hill J, Bhosale G et al.
(
2024
)
.
Delocalized quinolinium-macrocyclic peptides, an atypical chemotype for CNS penetration
.
Science Advances
vol.
10
,
(
28
)
Thomson A, Horne R, Chapman C, Bharadia T, Burke P, Colwell E, Harrington M, Boskovic B et al.
(
2024
)
.
Engaging a community to focus on upper limb function in people with multiple sclerosis: the ThinkHand campaign case study
.
Research Involvement and Engagement
vol.
10
,
(
1
)
Mistry N, Hobart J, Rog D, Muhlert N, Mathews J, Baker D, Giovannoni G
(
2024
)
.
Reconciling lesions, relapses and smouldering associated worsening: A unifying model for multiple sclerosis pathogenesis
.
Multiple Sclerosis and Related Disorders
vol.
88
,
Ammoscato F, Skonieczna J, Bestwick J, Holden D, Aboulwafa M, Andrews M, Turner B, Marta M et al.
(
2024
)
.
Prospective Longitudinal Study of Cladribine Tablets (CLADB Study) Demonstrates Sustained Reduction in Kappa Free Light Chains in Relapsing Multiple Sclerosis (RRMS) at 96 Weeks (P10-6.008)
.
Neurology
vol.
102
,
(
17_supplement_1
)
Zhang JZ, Nguyen WH, Greenwood N, Rose JC, Ong S-E, Maly DJ, Baker D
(
2024
)
.
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
.
Nature Biotechnology
vol.
42
,
(
12
)
1888
-
1898
.
Baker D, Church G
(
2024
)
.
Protein design meets biosecurity
.
Science
vol.
383
,
(
6681
)
349
-
349
.
Neunie OAM, Rabbani W, Baker D, Chambers ES, Pfeffer PE, Kang AS
(
2024
)
.
Immunogenicity of biologics used in the treatment of asthma
.
Human Antibodies
vol.
32
,
(
3
)
121
-
128
.
Baker D, Kang AS, Giovannoni G, Schmierer K
(
2023
)
.
Neutropenia following immune-depletion, notably CD20 targeting, therapies in multiple sclerosis
.
Multiple Sclerosis and Related Disorders
vol.
82
,
Allen-Philbey K, De Trane S, MacDougall A, Adams A, Bianchi L, Campion T, Giovannoni G, Gnanapavan S et al.
(
2023
)
.
Disease activity 4.5 years after starting cladribine: experience in 264 patients with multiple sclerosis
.
Therapeutic Advances in Neurological Disorders
vol.
16
,
Baker D
(
2023
)
.
Proteomic interrogation of the meninges reveals the molecular identities of structural components and regional distinctions along the CNS axis
.
Fluids and Barriers of the CNS
Dubuisson N, de Maere d'Aertrijcke O, Marta M, Gnanapavan S, Turner B, Baker D, Schmierer K, Giovannoni G et al.
(
2023
)
.
Anaesthetic management of people with multiple sclerosis
.
Multiple Sclerosis and Related Disorders
vol.
80
,
Seaton A, Baker D, Hedstrom AK, Alfredsson L, Schmierer K
(
2023
)
.
Organic solvents and Multiple Sclerosis: the doubled risk dilemma
.
Occupational Medicine
vol.
73
,
(
6
)
300
-
303
.
Dobson R
(
2023
)
.
Risk of COVID-19 in people with multiple sclerosis who are seronegative following vaccination
.
Multiple Sclerosis Journal
Baker D
(
2023
)
.
Neuroprotection in an
Experimental Model of Multiple
Sclerosis via Opening of Big
Conductance, Calcium-Activated
Potassium Channels
.
Pharmaceuticals
vol.
16
,
972
-
972
.
van Noort JM, Baker D, Kipp M, Amor S
(
2023
)
.
The pathogenesis of multiple sclerosis: a series of unfortunate events
.
Clinical & Experimental Immunology
vol.
214
,
(
1
)
1
-
17
.
Baker D, Forte E, Pryce G, Kang AS, James LK, Giovannoni G, Schmierer K
(
2022
)
.
The impact of sphingosine-1-phosphate receptor modulators on COVID-19 and SARS-CoV-2 vaccination
.
Multiple Sclerosis and Related Disorders
vol.
69
,
Baker D, Vainchtein ID
(
2022
)
.
Characterizing microglial gene expression in a model of secondary progressive MS
.
Glia
Licht‐Mayer S, Campbell GR, Mehta AR, McGill K, Symonds A, Al‐Azki S, Pryce G, Zandee S et al.
(
2022
)
.
Axonal response of mitochondria to demyelination and complex IV activity within demyelinated axons in experimental models of multiple sclerosis
.
Neuropathology and Applied Neurobiology
vol.
49
,
(
1
)
Schmierer K, Redha I, Hammond V, Baker D, Barkhof F, Hooper R, Rashid W, Singh-Curry V et al.
(
2022
)
.
152 AttackMS natalizumab for the treatment of people with inflammatory demyeli- nation suggestive of multiple sclerosis
.
Journal of Neurology Neurosurgery & Psychiatry
.
vol.
93
,
Schmierer K, Baker D, Nawaz T, Allen-Philbey K, Barkhof F, Chataway J, Hooper R, Mihaylova B et al.
(
2022
)
.
153 ChariotMS – cladribine to halt deterioration in people with advanced multiple sclerosis (pwAMS)
.
Journal of Neurology Neurosurgery & Psychiatry
.
vol.
93
,
K A-P, A S, T B, AC J, A M, S G, R D, G G et al.
(
2022
)
.
Did it hurt? COVID-19 vaccination experience in people with multiple sclerosis
.
Multiple Sclerosis and Related Disorders
vol.
65
,
Tallantyre EC, Scurr MJ, Vickaryous N, Richards A, Anderson V, Baker D, Chance R, Evangelou N et al.
(
2022
)
.
Response to COVID-19 booster vaccinations in seronegative people with multiple sclerosis
.
Multiple Sclerosis and Related Disorders
vol.
64
,
Baker D, MacDougall A, Kang AS, Schmierer K, Giovannoni G, Dobson R
(
2022
)
.
Seroconversion following COVID-19 vaccination: can we optimize protective response in CD20-treated individuals?
.
Clin Exp Immunol
vol.
207
,
(
3
)
263
-
271
.
Nutma E, Fancy N, Weinert M, Marzin MC, Tsartsalis S, Muirhead RCJ, Falk I, de Bruin J et al.
(
2022
)
.
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases
.
Allen-Philbey K, Marta M, Gnanapavan S, Baker D, Schmierer K
(
2022
)
.
Disease activity after cladribine immune reconstitution therapy: To repeat or to retreat? (P9-4.002)
.
Neurology
vol.
98
,
(
18_supplement
)
Guo L, Luong V, Gregson A, Baker D, Selwood D, Cordeiro MF
(
2022
)
.
VSN16S, an agonist of the cannabinoid receptor, reduces IOP profiles and exhibits neuroprotective properties in a rat model of glaucoma
.
Acta Ophthalmologica
vol.
100
,
(
S267
)
Ichimura Y, Baker D
(
2022
)
.
Acute Inhalational Injury
.
Encyclopedia of Respiratory Medicine
,
Elsevier
Allen-Philbey K, Andrews M, Redha I, Papachatzaki M, Marta M, Gnanapavan S, Mathews J, Turner B et al.
(
2022
)
.
CLADRIPLAS: Does cladribine Target CNS plasma cells and reduce neuro-axonal damage in people with MS?
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
28
,
769
-
770
.
Vickaryous N, Rios F, Schalk L, Asardag AN, George K, Kang A, Baker D, Giovannoni G et al.
(
2022
)
.
COVID-19 humoral and T-cell mediated vaccination responses in people with multiple sclerosis
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
28
,
680
-
680
.
Upcott M, Tallantyre EC, Scurr MJ, Vickaryous N, Richards A, Anderson V, Baker D, Chance R et al.
(
2022
)
.
Humoral and T- cell response to multiple COVID-19 booster vaccinations in people with MS
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
28
,
365
-
366
.
Baker D
(
2021
)
.
CD19 B cell repopulation after ocrelizumab, alemtuzumab and cladribine: Implications for SARS-CoV-2 vaccinations in multiple sclerosis
.
Multiple Sclerosis and Related Disorders
Allen-Philbey K, De Trane S, Mao Z, Álvarez-González C, Mathews J, MacDougall A, Stennett A, Zhou X et al.
(
2021
)
.
Subcutaneous cladribine to treat multiple sclerosis: experience in 208 patients
.
Therapeutic Advances in Neurological Disorders
vol.
14
,
Smets I, Holden D, Bianchi L, Ammoscato F, Allen-Philbey K, Baker D, Turner B, Marta M et al.
(
2021
)
.
Factors contributing to CSF NfL reduction over time in those starting treatment for multiple sclerosis: An observational study
.
Multiple Sclerosis and Related Disorders
vol.
57
,
Rupnik M, Baker D, Selwood DL
(
2021
)
.
Oligodendrocytes, BK channels and the preservation of myelin
.
F1000Research
vol.
10
,
Dobson R, Baker D, Kang A, Schmierer K, Giovannoni G
(
2021
)
.
COVID-19 vaccine response in people with multiple sclerosis
.
Annals of Neurology
Marta M, Baker D, Creeke P, Pryce G, Gnanapavan S, Giovannoni G
(
2021
)
.
Antigen-specific tolerization in human autoimmunity: Inhibition of interferon-beta1a anti-drug antibodies in multiple sclerosis: A case report
.
Multiple Sclerosis and Related Disorders
vol.
56
,
Rupnik M, Baker D, Selwood DL
(
2021
)
.
Oligodendrocytes, BK channels and remyelination
.
F1000Research
vol.
10
,
Baker D, Asardag AN, Quinn OA, Efimov A, Kang AS
(
2021
)
.
Anti-drug antibodies to antibody-based therapeutics in multiple sclerosis
.
Hum Antibodies
Giovannoni G, Hawkes CH, Lechner-Scott J, Levy M, Yeh EA, Baker D
(
2021
)
.
COVID-19 vaccines and multiple sclerosis disease-modifying therapies
.
Multiple Sclerosis and Related Disorders
vol.
53
,
Patel V, Efimov A, Baker D, Kang AS
(
2021
)
.
Immunogenicity of biologics used in the treatment of moderate to severe psoriasis
.
Human Antibodies
vol.
29
,
(
3
)
171
-
178
.
Hurley MJ, Deacon RMJ, Chan AWE, Baker D, Selwood DL, Cogram P
(
2021
)
.
Reversal of behavioural phenotype by the cannabinoid-like compound VSN16R in fragile X syndrome mice
.
Brain
vol.
145
,
(
1
)
76
-
82
.
Bqain M, Efimov A, Baker D, Kang AS
(
2021
)
.
Immunogenicity of biologics used in the treatment of inflammatory bowel disease: A review
.
Human Antibodies
Baker D, Hadjicharalambous C, Gnanapavan S, Giovannoni G
(
2021
)
.
Can rheumatologists stop causing demyelinating disease?
.
Multiple Sclerosis and Related Disorders
vol.
53
,
Dobson R, ALLEN-PHILBEY K, Giovannoni G, Baker D, Schmierer K
(
2021
)
.
Experience with the COVID-19 AstraZeneca vaccination in people with multiple sclerosis
.
Multiple Sclerosis and Related Disorders
Allen-Philbey K, De Trane S, Stennett A, Yildiz O, Adams A, Turner B, Marta M, Gnanapavan S et al.
(
2021
)
.
Cladribine personalised dosing for active multiple sclerosis: BartsMS cohort follow-up (2528)
.
Neurology
vol.
96
,
(
15_supplement
)
Schmierer K, Sørensen PS, Baker D
(
2021
)
.
Highly effective disease-modifying treatment as initial MS therapy
.
Current Opinion in Neurology
vol.
34
,
(
3
)
286
-
294
.
Smets I, Reyes S, Baker D, Giovannoni G
(
2021
)
.
Blunted vaccines responses after ocrelizumab highlight need for immunizations prior to treatment
.
Multiple Sclerosis and Related Disorders
vol.
50
,
Allen-Philbey K, De Trane S, Stennett A, Yildiz O, Adams A, Turner B, Marta M, Gnanapavan S et al.
(
2021
)
.
Cladribine Personalised Dosing to Treat Active Multiple Sclerosis - Follow-up in 250 patients
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
27
,
90
-
91
.
Allen-Philbey K, De Trane S, Stennett A, Yildiz O, Adams A, Turner B, Marta M, Gnanapavan S et al.
(
2021
)
.
Cladribine personalised dosing for active multiple sclerosis: BartsMS cohort follow-up
.
NEUROLOGY
.
vol.
96
,
Smets I, Holden D, Bianchi L, Ammoscato F, Allen-Philbey K, Baker D, Turner B, Marta M et al.
(
2021
)
.
Factors contributing to CSF NfL reduction over time in people with multiple sclerosis starting treatment: an observational study
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
27
,
514
-
515
.
Vickaryous N, Asardag AN, Chance R, Jones M, Bestwick J, Shah SN, George K, Schmierer K et al.
(
2021
)
.
Seroconversion following vaccination against SARS-CoV-2 in people with MS: impact of disease modifying therapy
.
MULTIPLE SCLEROSIS JOURNAL
vol.
27
,
(
2_SUPPL
)
775
-
776
.
Allen-Philbey K, De Trane S, Stennett A, Yildiz O, Adams A, Turner B, Marta M, Gnanapavan S et al.
(
2021
)
.
Up to 6 years follow-up of people with MS (n=250) receiving cladribine
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
27
,
546
-
547
.
Guo L, Luong V, Gregson A, Baker D, Selwood D, Cordeiro MF
(
2021
)
.
VSN16S, an agonist of the cannabinoid receptor, reduces IOP profiles and exhibits neuroprotective properties in a rat model of glaucoma
.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
.
vol.
62
,
Thomson A, Dobson R, Baker D, Giovannoni G
(
2020
)
.
Digesting science: Developing educational activities about multiple sclerosis, prevention and treatment to increase the confidence of affected families
.
Multiple Sclerosis and Related Disorders
vol.
47
,
Cunniffe N, Vuong KA, Ainslie D, Baker D, Beveridge J, Bickley S, Camilleri P, Craner M et al.
(
2020
)
.
Systematic approach to selecting licensed drugs for repurposing in the treatment of progressive multiple sclerosis
.
Journal of Neurology, Neurosurgery and Psychiatry
Amor S, Fernández Blanco L, Baker D
(
2020
)
.
Innate immunity during SARS-CoV-2: evasion strategies and activation trigger hypoxia and vascular damage
.
Clinical & Experimental Immunology
vol.
202
,
(
2
)
193
-
209
.
Mateo-Casas M, Reyes S, De Trane S, Edwards F, Espasandin M, Anjorin G, Baker D, Schmierer K et al.
(
2020
)
.
Severe lymphopenia after subcutaneous cladribine in a patient with multiple sclerosis: To vaccinate or not?
.
eNeurologicalSci
vol.
21
,
Jacobs B, Taylor T, Awad A, Baker D, Giovannoni G, Noyce A, Dobson R
(
2020
)
.
Summary-data-based mendelian randomisation prioritises potential druggable targets for Multiple Sclerosis
.
Brain Communications
Baker D, Roberts CAK, Pryce G, Kang AS, Marta M, Reyes S, Schmierer K, Giovannoni G et al.
(
2020
)
.
COVID-19 vaccine-readiness for anti-CD20-depleting therapy in autoimmune diseases
.
Clinical and Experimental Immunology
vol.
202
,
(
2
)
149
-
161
.
Petrova N, Nutma E, Carassiti D, Newman JR, Amor S, Altmann DR, Baker D, Schmierer K
(
2020
)
.
Synaptic Loss in Multiple Sclerosis Spinal Cord
.
Annals of Neurology
vol.
88
,
(
3
)
619
-
625
.
Baker D
(
2020
)
.
Enhanced axonal response of mitochondria to demyelination offers neuroprotection: implications for multiple sclerosis
.
Acta Neuropathologica
Saxena G, Moore JM, Jones M, Pryce G, Ali L, Leisegang GR, Vijay V, Loveless S et al.
(
2020
)
.
Detecting and predicting neutralization of alemtuzumab responses in MS
.
Neurology Neuroimmunology & Neuroinflammation
vol.
7
,
(
4
)
Baker D, Pryce G, James LK, Marta M, Schmierer K
(
2020
)
.
The ocrelizumab phase II extension trial suggests the potential to improve the risk:benefit balance in multiple sclerosis
.
Multiple Sclerosis and Related Disorders
Article
102279
,
102279
-
102279
.
Amor S, Baker D, Khoury SJ, Schmierer K, Giovanonni G
(
2020
)
.
SARS‐CoV‐2 and Multiple Sclerosis: Not All Immune Depleting DMTs are Equal or Bad
.
Annals of Neurology
vol.
87
,
(
6
)
794
-
797
.
Baker D, Amor S, Kang AS, Schmierer K, Giovannoni G
(
2020
)
.
The underpinning biology relating to multiple sclerosis disease modifying treatments during the COVID-19 pandemic
.
Multiple Sclerosis and Related Disorders
vol.
43
,
Mateo-Casas M, Reyes S, O'Toole EA, De Trane S, Yildiz O, Allen-Philbey K, Mathews J, Baker D et al.
(
2020
)
.
Severe skin reactions associated with cladribine in people with multiple sclerosis
.
Multiple Sclerosis and Related Disorders
.
vol.
43
,
Munger K, Kang A, Baker D, Goodman A, Samkoff L
(
2020
)
.
Alemtuzumab Depletion Failure and Neutralizing Anti-Drug Antibodies: a Case Report and Call for Monitoring (1347)
.
Neurology
vol.
94
,
(
15_supplement
)
Schmierer K, Baker D
(
2020
)
.
B cells and multiple sclerosis spinal cord pathology
.
Brain Pathology
vol.
30
,
(
4
)
730
-
731
.
Bertrand JA, Schicht M, Stamer WD, Baker D, Sherwood JM, Lütjen-Drecoll E, Selwood DL, Overby DR
(
2020
)
.
The beta(4)-Subunit of the Large-Conductance Potassium Ion Channel K(Ca)1.1 Regulates Outflow Facility in Mice
.
Investigative Ophthalmology and Visual Science
vol.
61
,
(
3
)
Ali L, SAXENA G, Jones M, Leisegang G, Gammon L, Gnanapavan S, Giovannoni G, Schmierer K et al.
(
2020
)
.
A cell-based assay for the detection of neutralizing antibodies against alemtuzumab
.
BioTechniques: the journal of laboratory technology for bioresearch
Baker D, Ali L, SAXENA G, Pryce G, Jones M, Schmierer K, Giovannoni G, Gnanapavan S et al.
(
2020
)
.
The irony of humanization: Alemtuzumab the first, but one of the most immunogenic, humanized monoclonal antibodies
.
Frontiers in Immunology
vol.
11
,
(
124
)
Saxena GK, Theocharopoulos I, Aziz NT, Jones M, Gnanapavan S, Giovannoni G, Schmierer K, Garnett JA et al.
(
2020
)
.
GloBody Technology: Detecting Anti-Drug Antibody against VH/VL domains
.
Scientific Reports
vol.
10
,
(
1
)
Article
1860
,
Baker D, Pryce G, James LK, Marta M, Schmierer K
(
2020
)
.
The ocrelizumab phase II extension trial suggests the potential to improve the risk:benefit balance in multiple sclerosis
.
Multiple Sclerosis and Related Disorders2020.01.09.20016774
-
2020.01.09.20016774
.
Munger K, Kang A, Baker D, Goodman A, Samkoff L
(
2020
)
.
Alemtuzumab depletion failure and neutralizing anti-drug antibodies: a case report and call for monitoring
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
26
,
258
-
258
.
Baker DJ
(
2020
)
.
Artificial Ventilation, A Basic Clinical Guide
.
Springer Nature
Allen-Philbey K, De Trane S, Stennett A, Yildiz O, Adams A, Turner B, Marta M, Gnanapavan S et al.
(
2020
)
.
Cladribine personalised dosing to treat multiple sclerosis: observations in 208 patients
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
26
,
522
-
523
.
Lieberman D, Mangat H, Allen-Philbey K, Baker D, Barkhof F, Chandran S, Chapman C, Chataway J et al.
(
2020
)
.
Cladribine to halt deterioration in people with advanced multiple sclerosis (CHARIOTMS)
.
MULTIPLE SCLEROSIS JOURNAL
.
vol.
26
,
212
-
213
.
Yager P, Abe K, Anderson CE, Baker D, Belousov Y, Bishop J, Buser JR, Byrnes SA et al.
(
2020
)
.
Low-cost disposable point-of-care devices based on porous materials for rapid detection of pathogens
.
21st International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2017
.
97
-
100
.
Baker D, Pryce G, James LK, Schmierer K, Giovannoni G
(
2019
)
.
Failed B cell survival factor trials support the importance of memory B cells in multiple sclerosis
.
European Journal of Neurology
vol.
27
,
(
2
)
221
-
228
.
Farrell R, Baker D
(
2019
)
.
An expert opinion: Optimisation of pharmacological management of multiple sclerosis related spasticity
.
Advances in Clinical Neuroscience and Rehabilitation
vol.
18
,
(
5
)
17
-
19
.
Baker D, Amor S
(
2019
)
.
Autoimmune encephalomyelitis in NOD mice is not initially a progressive multiple sclerosis model
.
Annals of Clinical and Translational Neurology
Batcheller L, Baker D
(
2019
)
.
Cost of disease modifying therapies for multiple sclerosis: Is front-loading the answer?
.
Journal of the Neurological Sciences
vol.
404
,
19
-
28
.
Tabatabaee S, Baker D, Selwood DL, Whalley BJ, Stephens GJ
(
2019
)
.
The Cannabinoid-Like Compound, VSN16R, Acts on Large Conductance, Ca2+-Activated K+ Channels to Modulate Hippocampal CA1 Pyramidal Neuron Firing
.
Pharmaceuticals
vol.
12
,
(
3
)
Baker D, Jacobs BM, Gnanapavan S, Schmierer K, Giovannoni G
(
2019
)
.
Plasma cell and B cell-targeted treatments for use in advanced multiple sclerosis
.
Multiple Sclerosis and Related Disorders
vol.
35
,
19
-
25
.
Pryce G, Baker D
(
2019
)
.
CHAPTER 11 Cannabinoids as a Therapeutic Approach in Multiple Sclerosis
.
Emerging Drugs and Targets for Multiple Sclerosis
,
Royal Society of Chemistry (RSC)
De Trane S, Mao Z, Alvarez-Gonzalez C, Allen-Philbey K, Yildiz O, Campion T, Adams A, Turner B et al.
(
2019
)
.
Cladribine to treat Relapsing and Progressive Multiple Sclerosis - experience in >200 patients (S26.008)
.
Neurology
vol.
92
,
(
15_supplement
)
Baker D, Pryce G, Herrod SS, Schmierer K
(
2019
)
.
Potential mechanisms of action related to the efficacy and safety of cladribine
.
Multiple Sclerosis and Related Disorders
vol.
30
,
176
-
186
.
Pryce G, Baker D
(
2019
)
.
CHAPTER 11: Cannabinoids as a Therapeutic Approach in Multiple Sclerosis
.
RSC Drug Discovery Series
,
vol.
2019-January
,
Day AL, Greisen P, Doyle L, Schena A, Stella N, Johnsson K, Baker D, Stoddard B
(
2018
)
.
Unintended specificity of an engineered ligand-binding protein facilitated by unpredicted plasticity of the protein fold
.
Protein Engineering Design and Selection
vol.
31
,
(
10
)
375
-
387
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O'Neill JK, Baker D, Turk JL
(
1992
)
.
Inhibition of chronic relapsing experimental allergic encephalomyelitis in the Biozzi AB/H mouse
.
Journal of Neuroimmunology
vol.
41
,
(
2
)
177
-
187
.
O'Neill JK, Baker D, Davison AN, Maggon KK, Jaffee BD, Turk JL
(
1992
)
.
Therapy of chronic relapsing experimental allergic encephalomyelitis and the role of the blood-brain barrier: elucidation by the action of Brequinar sodium
.
Journal of Neuroimmunology
vol.
38
,
(
1-2
)
53
-
62
.
Baker D, Davison AN
(
1991
)
.
Mechanisms of immune-mediated demyelinating disease of the central nervous system
.
Neurochemical Research
vol.
16
,
(
9
)
1067
-
1072
.
Butter C, O'Neill JK, Baker D, Gschmeissner SE, Turk JL
(
1991
)
.
An immunoelectron microscopical study of the expression of class II major histocompatibility complex during chronic relapsing experimental allergic encephalomyelitis in Biozzi AB/H mice
.
J Neuroimmunol
vol.
33
,
(
1
)
37
-
42
.
Butter C, Baker D, O'Neill JK, Turk JL
(
1991
)
.
Mononuclear cell trafficking and plasma protein extravasation into the CNS during chronic relapsing experimental allergic encephalomyelitis in Biozzi AB/H mice
.
J Neurol Sci
vol.
104
,
(
1
)
9
-
12
.
Baker D, O'Neill JK, Turk JL
(
1991
)
.
Cytokines in the central nervous system of mice during chronic relapsing experimental allergic encephalomyelitis
.
Cellular Immunology
vol.
134
,
(
2
)
505
-
510
.
O'Neill JK, Butter C, Baker D, Gschmeissner SE, Kraal G, Butcher EC, Turk JL
(
1991
)
.
Expression of vascular addressins and ICAM-1 by endothelial cells in the spinal cord during chronic relapsing experimental allergic encephalomyelitis in the Biozzi AB/H mouse
.
Immunology
vol.
72
,
(
4
)
520
-
525
.
Baker D, Kimber I, Ahmed K, Turk JL
(
1991
)
.
Antigen-specific and non-specific depression of proliferative responses induced during contact sensitivity in mice
.
International Journal of Experimental Pathology
vol.
72
,
(
1
)
55
-
65
.
Baker D, O'Neill JK, Amor S, Khamashta MA, Turk JL
(
1991
)
.
Inhibition of chronic relapsing experimental allergic encephalomyelitis in the mouse by the alkyl-lysophospholipid ET-18-OCH<inf>3</inf>
.
International Journal of Immunopharmacology
vol.
13
,
(
4
)
385
-
392
.
Watson CM, Davison AN, Baker D, O'Neill JK, Turk JL
(
1991
)
.
Suppression of demyelination by mitoxantrone
.
Int J Immunopharmacol
vol.
13
,
(
7
)
923
-
930
.
Wilcox CE, Ward AM, Evans A, Baker D, Rothlein R, Turk JL
(
1990
)
.
Endothelial cell expression of the intercellular adhesion molecule-1 (ICAM-1) in the central nervous system of guinea pigs during acute and chronic relapsing experimental allergic encephalomyelitis
.
J Neuroimmunol
vol.
30
,
(
1
)
43
-
51
.
Baker D, O'Neill JK, Gschmeissner SE, Wilcox CE, Butter C, Turk JL
(
1990
)
.
Induction of chronic relapsing experimental allergic encephalomyelitis in Biozzi mice
.
Journal of Neuroimmunology
vol.
28
,
(
3
)
261
-
270
.
Schäfer H, Baker D, Thiele B, Burger R
(
1990
)
.
Structure, cellular distribution, and functional characteristics of the guinea pig leucocyte common antigen
.
Cellular Immunology
vol.
128
,
(
2
)
370
-
384
.
Kimber I, Cumberbatch M, Bentley AN, Baker D
(
1990
)
.
Requirements for antigenic competition in contact sensitivity
.
Journal of Clinical and Laboratory Immunology
vol.
32
,
(
2
)
67
-
72
.
Butter C, Healey DG, Baker D, Turk JL
(
1989
)
.
A quantitative immunocytochemical study of the infiltrating lymphocytes in the spinal cord of guinea pigs with chronic relapsing experimental allergic encephalomyelitis
.
J Neuroimmunol
vol.
25
,
(
2-3
)
169
-
176
.
Wilcox CE, Healey DG, Baker D, Willoughby DA, Turk JL
(
1989
)
.
Presentation of myelin basic protein by normal guinea-pig brain endothelial cells and its relevance to experimental allergic encephalomyelitis
.
Immunology
vol.
67
,
(
4
)
435
-
440
.
Wilcox CE, Baker D, Butter C, Willoughby DA, Turk JL
(
1989
)
.
Differential expression of guinea pig class II major histocompatibility complex antigens on vascular endothelial cells in vitro and in experimental allergic encephalomyelitis
.
Cell Immunol
vol.
120
,
(
1
)
82
-
91
.
Kimber I, Shepherd CJ, Mitchell JA, Turk JL, Baker D
(
1989
)
.
Regulation of lymphocyte proliferation in contact sensitivity: homeostatic mechanisms and a possible explanation of antigenic competition
.
Immunology
vol.
66
,
(
4
)
577
-
582
.
Baker D, Kimber I, Turk JL
(
1989
)
.
Antigen-specific regulation of T lymphocyte proliferative responses to contact-sensitizing chemicals in the guinea pig
.
Cellular Immunology
vol.
119
,
(
1
)
153
-
159
.
Kraal G, Shiamatey-Koolma R, Hoffer M, Baker D, Scheper R
(
1988
)
.
Histochemical identification of guinea-pig macrophages by monoclonal antibody MR-1
.
Immunology
vol.
65
,
(
4
)
523
-
528
.
Baker D, Parker D, Healey DG, Turk JL
(
1987
)
.
Induction of sensitization and tolerance in contact sensitivity with haptenated epidermal cells in the guinea-pig
.
Immunology
vol.
62
,
(
4
)
659
-
664
.
Antoniou AV, Baker D, El-Sady E, Turk JL, Tan BTG, Scheper RJ
(
1987
)
.
Identification and quantitation of the expression of T cell surface markers during the development of chronic relapsing experimental allergic encephalomyelitis (CREAE) in the guinea pig
.
Journal of Neuroimmunology
vol.
14
,
(
3
)
293
-
303
.
BAKER D, PARKER DD, TURK JL
(
1985
)
.
Effect of depletion of epidermal dendritic cells on the induction of contact sensitivity in the guinea‐pig
.
British Journal of Dermatology
vol.
113
,
(
3
)
285
-
294
.