Publications: Dr Jesmond Dalli

Dalli J, Kitch D, O'Brien MP, Hunt PW, Funderburg N, Moisi D, Gupta A, Brown TT et al. ( 2023 ) . Pro-inflammatory and pro-resolving lipid mediators of inflammation in HIV: effect of aspirin intervention . eBioMedicine vol. 89 ,

Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al. ( 2023 ) . Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis . JCI insight vol. 8 , ( 3 )

Perretti M, Dalli J ( 2023 ) . Resolution Pharmacology: Focus on Pro-Resolving Annexin A1 and Lipid Mediators for Therapeutic Innovation in Inflammation . Annual review of pharmacology and toxicology vol. 63 , 449 - 469 .

Rathod KS, Kapil V, Velmurugan S, Khambata RS, Siddique U, Khan S, Van Eijl S, Gee LC et al. ( 2023 ) . Erratum: Accelerated resolution of inflammation underlies sex differences in inflammatory responses in humans (J Clin Invest. (2017) 127: 1 (169–182) DOI: 10.1172/JCI89429) . Journal of Clinical Investigation vol. 133 , ( 2 )

Flak MB, Koenis DS, Gonzalez-Nunez M, Chopo-Pizarro A, Dalli J ( 2023 ) . Deletion of macrophage Gpr101 disrupts their phenotype and function dysregulating host immune responses in sterile and infectious inflammation . Biochemical Pharmacology vol. 207 ,

Díaz Del Campo LS, García-Redondo AB, Rodríguez C, Zaragoza C, Duro-Sánchez S, Palmas F, De Benito-Bueno A, Socuéllamos PG et al. ( 2023 ) . Resolvin D2 Attenuates Cardiovascular Damage in Angiotensin II-Induced Hypertension . Hypertension vol. 80 , ( 1 ) 84 - 96 .

Silva RA, Domingos R, Trujillo M, Filho A, Oliveira C, Baldini R, Dalli J, Netto L ( 2022 ) . LsfA, a 1-Cys Peroxiredoxin involved with Pseudomonas aeruginosa virulence: Structure, biochemical activity, and its influence in inflammation/resolution . Free Radical Biology and Medicine vol. 192 ,

Flak MB, Colas RA, Muñoz-Atienza E, Curtis MA, Dalli J, Pitzalis C ( 2022 ) . Corrigendum: Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis (JCI Insight (2019) 4:13 (e125191) DOI: 10.1172/jci.insight.125191) . JCI Insight vol. 7 , ( 20 )

Dalli J, Rodriguez A, Spur B, Serhan C ( 2022 ) . Structure elucidation and biological evaluations of sulfido-conjugated specialized pro-resolving mediators . Conference: Proceedings of 2022 AOCS Annual Meeting & Expo

Sips M, Gerlo S, De Clercq L, Gomez EA, Colas RA, Dalli J, Vandekerckhove L ( 2022 ) . Distinct immune profiles of HIV-infected subjects are linked to specific lipid mediator signature . Immunity, Inflammation and Disease vol. 10 , ( 6 )

Caravaca AS, Gallina AL, Tarnawski L, Shavva VS, Colas RA, Dalli J, Malin SG, Hult H et al. ( 2022 ) . Vagus nerve stimulation promotes resolution of inflammation by a mechanism that involves Alox15 and requires the α7nAChR subunit . Proceedings of the National Academy of Sciences of the United States of America vol. 119 , ( 22 )

Keogh A, Clarke J, Rabani R, Dalli J, Godson C, Curley G ( 2022 ) . Lipoxin A4 Mediates Mesenchymal Stromal Cell Therapeutic Effects in Sepsis . Conference: A101. DEFINING CELLULAR AND MOLECULAR IMMUNE MECHANISMS IN LUNG INFECTIONS, ARDS, AND SEPSISa2198 - a2198 .

Pistorius K, Ly L, Souza PR, Gomez EA, Koenis DS, Rodriguez AR, Foster J, Sosabowski J et al. ( 2022 ) . MCTR3 reprograms arthritic monocytes to upregulate Arginase-1 and exert pro-resolving and tissue-protective functions in experimental arthritis . eBioMedicine vol. 79 ,

Dalli J, Gomez E, Serhan C ( 2022 ) . Evidence for the presence and diagnostic utility of SPM in human peripheral blood .

Hamers A, Primus CP, Whitear C, Kumar NA, Masucci M, Montalvo Moreira SA, Rathod K, Chen J et al. ( 2022 ) . 20-hydroxyeicosatetraenoic acid (20-HETE) is a pivotal endogenous ligand for TRPV1-mediated neurogenic inflammation in the skin . British Journal of Pharmacology vol. 179 , ( 7 ) 1450 - 1469 .

Dyall SC, Balas L, Bazan NG, Brenna JT, Chiang N, da Costa Souza F, Dalli J, Durand T et al. ( 2022 ) . Polyunsaturated fatty acids and fatty acid-derived lipid mediators: Recent advances in the understanding of their biosynthesis, structures, and functions . Progress in Lipid Research vol. 86 ,

Mikroulis A, Ledri M, Ruffolo G, Palma E, Sperk G, Dalli J, Vezzani A, Kokaia M ( 2022 ) . Lipid mediator n-3 docosapentaenoic acid-derived protectin D1 enhances synaptic inhibition of hippocampal principal neurons by interaction with a G-protein-coupled receptor . FASEB Journal vol. 36 , ( 3 )

Kraft JD, Blomgran R, Bergström I, Soták M, Clark M, Rani A, Rajan MR, Dalli J et al. ( 2022 ) . Lipoxins modulate neutrophil oxidative burst, integrin expression and lymphatic transmigration differentially in human health and atherosclerosis . FASEB Journal vol. 36 , ( 3 )

Dalli J, Gomez EA, Jouvene CC ( 2022 ) . Utility of the Specialized Pro-Resolving Mediators as Diagnostic and Prognostic Biomarkers in Disease . Biomolecules vol. 12 , ( 3 )

de Matteis R, Flak MB, Gonzalez-Nunez M, Austin-Williams S, Palmas F, Colas RA, Dalli J ( 2022 ) . Aspirin activates resolution pathways to reprogram T cell and macrophage responses in colitis-associated colorectal cancer . Science Advances vol. 8 , ( 5 )

Reinertsen AF, Primdahl KG, De Matteis R, Dalli J, Hansen TV ( 2022 ) . Stereoselective Synthesis, Configurational Assignment and Biological Evaluations of the Lipid Mediator RvD2<inf>n-3 DPA</inf> . Chemistry - A European Journal vol. 28 , ( 7 )

Marques RM, Gonzalez-Nunez M, Walker ME, Gomez EA, Colas RA, Montero-Melendez T, Perretti M, Dalli J ( 2021 ) . Loss of 15-lipoxygenase disrupts T<inf>reg</inf> differentiation altering their pro-resolving functions . Cell Death and Differentiation vol. 28 , ( 11 ) 3140 - 3160 .

Piattini F, Matsushita M, Muri J, Bretscher P, Feng X, Freigang S, Dalli J, Schneider C et al. ( 2021 ) . Differential sensitivity of inflammatory macrophages and alternatively activated macrophages to ferroptosis . European Journal of Immunology vol. 51 , ( 10 ) 2417 - 2429 .

Beegun I, Koenis DS, Alusi G, Dalli J ( 2021 ) . Dysregulated Maresin Concentrations in Plasma and Nasal Secretions From Patients With Chronic Rhinosinusitis . Frontiers in Immunology vol. 12 ,

Palmas F, Clarke J, Colas RA, Gomez EA, Keogh A, Boylan M, McEvoy N, McElvaney OJ et al. ( 2021 ) . Dysregulated plasma lipid mediator profiles in critically ill COVID-19 patients . PLoS ONE vol. 16 , ( 8 August )

Koenis DS, Beegun I, Jouvene CC, Aguirre GA, Souza PR, Gonzalez-Nunez M, Ly L, Pistorius K et al. ( 2021 ) . Disrupted Resolution Mechanisms Favor Altered Phagocyte Responses in COVID-19 . Circulation ResearchE54 - E71 .

Rossaint J, Thomas K, Mersmann S, Skupski J, Margraf A, Tekath T, Jouvene CC, Dalli J et al. ( 2021 ) . Platelets orchestrate the resolution of pulmonary inflammation in mice by T reg cell repositioning and macrophage education . The Journal of experimental medicine vol. 218 , ( 7 )

Jagusch H, Werner M, Koenis D, Dalli J, Werz O, Pohnert G ( 2021 ) . 14,17,18-Trihydroxy-Eicosatetraenoic Acid: A Novel Pro-Resolving Lipid Mediator from Marine Microalgae . ACS Pharmacology and Translational Science vol. 4 , ( 3 ) 1188 - 1194 .

Félix-Soriano E, Sáinz N, Gil-Iturbe E, Collantes M, Fernández-Galilea M, Castilla-Madrigal R, Ly L, Dalli J et al. ( 2021 ) . Changes in brown adipose tissue lipid mediator signatures with aging, obesity, and DHA supplementation in female mice . FASEB Journal vol. 35 , ( 6 )

Keogh A, Clarke J, Rabani R, Dalli J, Curley GF ( 2021 ) . Lipoxin A4 as a Mediator of Mesenchymal Stromal Cell Therapeutic Effects in Pulmonary Sepsis . Conference: TP4. TP004 ARDS, SEPSIS, AND TRANSPLANTATION MECHANISTIC STUDIESa1317 - a1317 .

Sokal DM, McSloy A, Donegà M, Kirk J, Colas RA, Dolezalova N, Gomez EA, Gupta I et al. ( 2021 ) . Splenic Nerve Neuromodulation Reduces Inflammation and Promotes Resolution in Chronically Implanted Pigs . Frontiers in Immunology vol. 12 ,

Sogorb-Esteve A, Colas RA, Dalli J, Rohrer JD ( 2021 ) . Differential Lipid Mediator Involvement in the Different Forms of Genetic Frontotemporal Dementia: Novel Insights into Neuroinflammation . Journal of Alzheimer's Disease vol. 84 , ( 1 ) 283 - 289 .

Gomez EA, Colas RA, Souza PR, Hands R, Lewis MJ, Bessant C, Pitzalis C, Dalli J ( 2020 ) . Blood pro-resolving mediators are linked with synovial pathology and are predictive of DMARD responsiveness in rheumatoid arthritis . Nature Communications vol. 11 , ( 1 )

Wood EG, Macdougall CE, Blythe H, Clément M, Colas RA, Dalli J, Marelli-Berg F, Longhi MP ( 2020 ) . HIF1α activation in dendritic cells under sterile conditions promotes an anti-inflammatory phenotype through accumulation of intracellular lipids . Scientific Reports vol. 10 , ( 1 )

Sobrino A, Walker ME, Colas RA, Dalli J ( 2020 ) . Protective activities of distinct omega-3 enriched oils are linked to their ability to upregulate specialized pro-resolving mediators . PLoS ONE vol. 15 , ( 12 December )

Colas R, Gomez E, Dalli J ( 2020 ) . Methodologies and Procedures Employed in the Identification and Quantitation of Lipid Mediators via LC-MS/MS .

Plebani R, Colas RA, Mattoscio D, Trerotola M, Gomez EA, Isopi E, Castagnozzi S, Dalli J et al. ( 2020 ) . CFTR ABLATION BY CRISPR/CAS9 IMPAIRS THE PRODUCTION OF PRO-RESOLVING LIPID MEDIATORS BY HUMAN AIRWAY EPITHELIAL CELLS . PEDIATRIC PULMONOLOGY . vol. 55 , S75 - S75 .

Souza PR, Walker ME, Goulding NJ, Dalli J, Perretti M, Norling LV ( 2020 ) . The GPR40 Agonist GW9508 Enhances Neutrophil Function to Aid Bacterial Clearance During E. coli Infections . Frontiers in Immunology vol. 11 , 573019 - 573019 .

Brancaleone V, Dalli J, d’Emmanuele di Villa Bianca R, Pace S ( 2020 ) . Editorial: Role of Blood Cells in Inflammatory and Vascular Disorders . Frontiers in Pharmacology vol. 11 ,

Chen J, Purvis GSD, Collotta D, Zoubi SA, Sugimoto MA, Cacace A, Martin L, Colas RA et al. ( 2020 ) . RvE1 Attenuates Polymicrobial Sepsis-Induced Cardiac Dysfunction and Enhances Bacterial Clearance . Frontiers in Immunology vol. 11 , 2080 - 2080 .

Schaller MS, Chen M, Colas RA, Sorrentino TA, Lazar AA, Grenon SM, Dalli J, Conte MS ( 2020 ) . Treatment with a marine oil supplement alters lipid mediators and leukocyte phenotype in healthy patients and those with peripheral artery disease . Journal of the American Heart Association vol. 9 , ( 15 )

Ruhanen H, Haridas PAN, Minicocci I, Taskinen JH, Palmas F, di Costanzo A, D'Erasmo L, Metso J et al. ( 2020 ) . ANGPTL3 deficiency alters the lipid profile and metabolism of cultured hepatocytes and human lipoproteins . Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids vol. 1865 , ( 7 )

Allen BL, Montague-Cardoso K, Simeoli R, Colas RA, Oggero S, Vilar B, McNaughton PA, Dalli J et al. ( 2020 ) . Imbalance of proresolving lipid mediators in persistent allodynia dissociated from signs of clinical arthritis . Pain

Fussbroich D, Colas RA, Eickmeier O, Trischler J, Jerkic SP, Zimmermann K, Göpel A, Schwenger T et al. ( 2020 ) . A combination of LCPUFA ameliorates airway inflammation in asthmatic mice by promoting pro-resolving effects and reducing adverse effects of EPA . Mucosal Immunology vol. 13 , ( 3 ) 481 - 492 .

Becares N, Härmälä S, China L, Colas RA, Maini AA, Bennet K, Skene SS, Shabir Z et al. ( 2020 ) . Immune Regulatory Mediators in Plasma from Patients With Acute Decompensation Are Associated With 3-Month Mortality . Clinical Gastroenterology and Hepatology vol. 18 , ( 5 ) 1207 - 1215.e6 .

Shivakoti R, Dalli J, Kadam D, Gaikwad S, Barthwal M, Colas RA, Mazzacuva F, Lokhande R et al. ( 2020 ) . Lipid mediators of inflammation and Resolution in individuals with tuberculosis and tuberculosis-Diabetes . Prostaglandins and Other Lipid Mediators vol. 147 ,

Pangopoulos MK, Nolsøe JMN, Antonsen SG, Colas RA, Dalli J, Aursnes M, Stenstrøm Y, Hansen TV ( 2020 ) . Enzymatic studies with 3-oxa n-3 DPA . Bioorganic Chemistry vol. 96 ,

Määttänen P, Lurz E, Botts SR, Wu RY, Robinson SC, Yeung CW, Colas R, Li B et al. ( 2020 ) . Plant- and Fish-Derived n-3 PUFAs Suppress Citrobacter Rodentium–Induced Colonic Inflammation . Molecular Nutrition and Food Research vol. 64 , ( 6 )

Wilcz-Villega E, Carter E, Ironside A, Xu R, Mataloni I, Holdsworth J, Jones W, Moreno Béjar R et al. ( 2020 ) . Macrophages induce malignant traits in mammary epithelium via IKKε/TBK1 kinases and the serine biosynthesis pathway . EMBO Molecular Medicine vol. 12 , ( 2 )

Flak MB, Koenis DS, Sobrino A, Smith J, Pistorius K, Palmas F, Dalli J ( 2020 ) . GPR101 mediates the pro-resolving actions of RvD5n-3 DPA in arthritis and infections . Journal of Clinical Investigation vol. 130 , ( 1 ) 359 - 373 .

Thau-Zuchman O, Ingram R, Harvey GG, Cooke T, Palmas F, Pallier PN, Brook J, Priestley JV et al. ( 2020 ) . A single injection of docosahexaenoic acid induces a pro-resolving lipid mediator profile in the injured tissue and a long-lasting reduction in neurological deficit after traumatic brain injury in mice . Journal of Neurotrauma vol. 37 , ( 1 ) 66 - 79 .

Souza PR, Marques RM, Gomez EA, Colas RA, De Matteis R, Zak A, Patel M, Collier DJ et al. ( 2019 ) . Enriched Marine Oil Supplements Increase Peripheral Blood Specialized Pro-Resolving Mediators Concentrations and Reprogram Host Immune Responses: A Randomized Double-Blind Placebo-Controlled Study . Circ Res

Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN et al. ( 2019 ) . Erratum to: Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1 n −3 DPA (Chemistry - A European Journal, (2019), 25, 6, (1476-1480), 10.1002/chem.201806029) . Chemistry - A European Journal vol. 25 , ( 66 )

Dakin SG, Colas RA, Wheway K, Watkins B, Appleton L, Rees J, Gwilym S, Little C et al. ( 2019 ) . Proresolving Mediators LXB4 and RvE1 Regulate Inflammation in Stromal Cells from Patients with Shoulder Tendon Tears . American Journal of Pathology vol. 189 , ( 11 ) 2258 - 2268 .

Colas RA, Nhat LTH, Thuong NTT, Gómez EA, Ly L, Thanh HH, Mai NTH, Phu NH et al. ( 2019 ) . Proresolving mediator profiles in cerebrospinal fluid are linked with disease severity and outcome in adults with tuberculous meningitis . FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 33 , ( 11 ) 13028 - 13039 .

Holopainen M, Colas RA, Valkonen S, Tigistu-Sahle F, Hyvärinen K, Mazzacuva F, Lehenkari P, Käkelä R et al. ( 2019 ) . Polyunsaturated fatty acids modify the extracellular vesicle membranes and increase the production of proresolving lipid mediators of human mesenchymal stromal cells . Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids vol. 1864 , ( 10 ) 1350 - 1362 .

Nesman JI, Primdahl KG, Tungen JE, Palmas F, Dalli J, Hansen TV ( 2019 ) . Synthesis, structural confirmation, and biosynthesis of 22-OH-PD1<inf>n-3 DPA</inf>^† . Molecules vol. 24 , ( 18 )

Fosshaug LE, Colas RA, Anstensrud AK, Gregersen I, Nymo S, Sagen EL, Michelsen A, Vinge LE et al. ( 2019 ) . Early increase of specialized pro-resolving lipid mediators in patients with ST-elevation myocardial infarction . EBioMedicine vol. 46 , 264 - 273 .

Valkonen S, Holopainen M, Colas RA, Impola U, Dalli J, Käkelä R, Siljander PRM, Laitinen S ( 2019 ) . Lipid mediators in platelet concentrate and extracellular vesicles: Molecular mechanisms from membrane glycerophospholipids to bioactive molecules . Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids vol. 1864 , ( 8 ) 1168 - 1182 .

Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L et al. ( 2019 ) . Proresolving mediators counter inflammation in stromal cells from patients with Achilles tendon disease . INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY . vol. 100 , A15 - A15 .

Flak MB, Colas RA, Muñoz-Atienza E, Curtis MA, Dalli J, Pitzalis C ( 2019 ) . Inflammatory arthritis disrupts gut resolution mechanisms, promoting barrier breakdown by Porphyromonas gingivalis . JCI Insight vol. 4 , ( 13 )

Dakin SG, Colas RA, Newton J, Gwilym S, Jones N, Reid HAB, Wood S, Appleton L et al. ( 2019 ) . 15-Epi-LXA<inf>4</inf> and MaR1 counter inflammation in stromal cells from patients with Achilles tendinopathy and rupture . FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 33 , ( 7 ) 8043 - 8054 .

Colas RA, Thwaites GE, Thuong NT, Ly L, Phu NH, Ramakrishnan L, Mai NT, Dalli J ( 2019 ) . Pro-resolving mediator profiles and 5-lipoxygenase activity in cerebrospinal fluids correlate with disease severity and outcomes in adults with tuberculosis meningitis . BRITISH JOURNAL OF CLINICAL PHARMACOLOGY . vol. 85 , 1639 - 1639 .

Dakin SG, Colas RA, Dean BJF, Wheway K, Watkins B, Dalli J, Carr AJ ( 2019 ) . Tendon cells isolated from patients with persistent shoulder tendinopathy show dysregulated resolution responses . Translational Sports Medicine vol. 2 , ( 4 ) 173 - 176 .

Sordi R, Chiazza F, Collotta D, Migliaretti G, Colas RA, Vulliamy P, Brohi K, Dalli J et al. ( 2019 ) . Resolvin D1 Attenuates the Organ Injury Associated With Experimental Hemorrhagic Shock . Ann Surg

López-Vicario C, Titos E, Walker ME, Alcaraz-Quiles J, Casulleras M, Durán-Güell M, Flores-Costa R, Pérez-Romero N et al. ( 2019 ) . Leukocytes from obese individuals exhibit an impaired SPM signature . FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol. 33 , ( 6 ) 7072 - 7083 .

Colas R, Nhat LTH, Thuong NTT, Cifuentes EAG, Ly L, Thanh HH, Phu NH, Mai NTH et al. ( 2019 ) . Pro-Resolving Mediator Profiles And 5-Lipoxygenase Activity In Cerebrospinal Fluid Correlate with Disease Severity and Outcome in Adults with Tuberculous Meningitis .

Becares N, Maini AA, Colas RA, Dalli J, Gilroy DW, O’brien A ( 2019 ) . FRI-109-Increased plasma leukotriene B4 in decompensated cirrhosis associates with disease progression and leads to increased skin window neutrophil infiltration . Journal of Hepatology . vol. 70 ,

Dalli J, Serhan CN ( 2019 ) . Identification and structure elucidation of the pro-resolving mediators provides novel leads for resolution pharmacology . British Journal of Pharmacology vol. 176 , ( 8 ) 1024 - 1037 .

Dalli J, Pistorius K, Walker ME ( 2019 ) . Novel n-3 Docosapentaneoic Acid-Derived Pro-resolving Mediators Are Vasculoprotective and Mediate the Actions of Statins in Controlling Inflammation . Advances in Experimental Medicine and Biology vol. 1161 , 65 - 75 .

Sønderskov J, Tungen JE, Palmas F, Dalli J, Serhan CN, Stenstrøm Y, Vidar Hansen T ( 2019 ) . Stereoselective synthesis of MaR2<inf>n-3 DPA</inf> . Tetrahedron Letters

Tungen JE, Gerstmann L, Vik A, De Matteis R, Colas RA, Dalli J, Chiang N, Serhan CN et al. ( 2018 ) . Resolving Inflammation: Synthesis, Configurational Assignment, and Biological Evaluations of RvD1n-3 DPA . Chemistry vol. 25 , ( 6 ) 1476 - 1480 .

Serhan CN, Chiang N, Dalli J ( 2018 ) . New pro-resolving n-3 mediators bridge resolution of infectious inflammation to tissue regeneration . Mol Aspects Med vol. 64 , 1 - 17 .

Laguna-Fernandez A, Checa A, Carracedo M, Artiach G, Petri MH, Baumgartner R, Forteza MJ, Jiang X et al. ( 2018 ) . ERV1/ChemR23 Signaling Protects Against Atherosclerosis by Modifying Oxidized Low-Density Lipoprotein Uptake and Phagocytosis in Macrophages . Circulation vol. 138 , ( 16 ) 1693 - 1705 .

Frigerio F, Pasqualini G, Craparotta I, Marchini S, van Vliet EA, Foerch P, Vandenplas C, Leclercq K et al. ( 2018 ) . n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis . Brain vol. 141 , ( 11 ) 3130 - 3143 .

Dalli J, Colas R, de Souza PRS ( 2018 ) . Impaired Production and Diurnal Regulation of Vascular RvD(n-3) DPA Increases Systemic Inflammation and Cardiovascular Disease . AMERICAN JOURNAL OF PATHOLOGY . vol. 188 , 2409 - 2409 .

Chiang N, Riley IR, Dalli J, Rodriguez AR, Spur BW, Serhan CN ( 2018 ) . New maresin conjugates in tissue regeneration pathway counters leukotriene D4–stimulated vascular responses . The FASEB Journal vol. 32 , ( 7 ) 4043 - 4052 .

Chen J, Hamers AJP, Finsterbusch M, Massimo G, Zafar M, Corder R, Colas RA, Dalli J et al. ( 2018 ) . Endogenously generated arachidonate-derived ligands for TRPV1 induce cardiac protection in sepsis . FASEB Jfj201701303R - fj201701303R .

Pistorius K, Souza PR, De Matteis R, Austin-Williams S, Primdahl KG, Vik A, Mazzacuva F, Colas RA et al. ( 2018 ) . PDn-3 DPA Pathway Regulates Human Monocyte Differentiation and Macrophage Function . Cell Chem Biol vol. 25 , ( 6 ) 749 - 760.e9 .

China L, Maini A, Skene SS, Shabir Z, Sylvestre Y, Colas RA, Ly L, Becares Salles N et al. ( 2018 ) . Albumin Counteracts Immune-Suppressive Effects of Lipid Mediators in Patients With Advanced Liver Disease . Clinical Gastroenterology and Hepatology vol. 16 , ( 5 ) 738 - 747.e7 .

Colas RA, Ashton AW, Mukherjee S, Dalli J, Akide-Ndunge OB, Huang H, Desruisseaux MS, Guan F et al. ( 2018 ) . Trypanosoma cruzi produces the specialized proresolving mediators resolvin D1, resolvin D5, and resolvin E2 . Infection and Immunity vol. 86 , ( 4 )

Motwani MP, Colas RA, George MJ, Flint JD, Dalli J, Richard-Loendt A, De Maeyer RP, Serhan CN et al. ( 2018 ) . Pro-resolving mediators promote resolution in a human skin model of UV-killed Escherichia coli-driven acute inflammation . JCI insight vol. 3 , ( 6 )

Colas RA, Souza PR, Walker ME, Burton M, Zasłona Z, Curtis AM, Marques RM, Dalli J ( 2018 ) . Impaired production and diurnal regulation of vascular RvD <inf>n-3 DPA</inf> increase systemic inflammation and cardiovascular disease . Circulation Research vol. 122 , ( 6 ) 855 - 863 .

Mai NT, Dobbs N, Phu NH, Colas RA, Thao LT, Thuong NT, Nghia HD, Hanh NH et al. ( 2018 ) . A randomised double blind placebo controlled phase 2 trial of adjunctive aspirin for tuberculous meningitis in HIV-uninfected adults . eLife vol. 7 ,

Dalli J, Serhan CN ( 2018 ) . Immunoresolvents signaling molecules at intersection between the brain and immune system . Current Opinion in Immunology vol. 50 , 48 - 54 .

Dalli J, Colas RA, Walker ME, Serhan CN ( 2018 ) . Lipid Mediator Metabolomics Via LC-MS/MS Profiling and Analysis . Methods Mol Biol vol. 1730 , 59 - 72 .

Dalli J ( 2018 ) . Omega-3 Fatty Acids and Resolution of Inflammation . ANNALS OF NUTRITION AND METABOLISM . vol. 73 , 190 - 190 .

Sulciner ML, Serhan CN, Gilligan MM, Mudge DK, Chang J, Gartung A, Lehner KA, Bielenberg DR et al. ( 2018 ) . Resolvins suppress tumor growth and enhance cancer therapy . Journal of Experimental Medicine vol. 215 , ( 1 ) 115 - 140 .

Dalli J ( 2017 ) . Does promoting resolution instead of inhibiting inflammation represent the new paradigm in treating infections? . Molecular Aspects of Medicine vol. 58 , 12 - 20 .

Frigerio F, Colas R, Marchini S, van Vliet E, Foerch P, Aronica E, Perretti M, Dalli J et al. ( 2017 ) . PRORESOLVING ANTIINFLAMMATORY MECHANISMS ARE NOVEL POTENTIAL TARGETS AGAINST EPILEPTOGENESIS . EPILEPSIA . vol. 58 , S5 - S5 .

Dalli J, Serhan CN ( 2017 ) . Pro-Resolving Mediators in Regulating and Conferring Macrophage Function . Front Immunol vol. 8 , 1400 - 1400 .

Motwani MP, Newson J, Kwong S, Richard-Loendt A, Colas R, Dalli J, Gilroy DW ( 2017 ) . Prolonged immune alteration following resolution of acute inflammation in humans . PLoS One vol. 12 , ( 10 ) Article e0186964 , e0186964 - e0186964 .

Primdahl KG, Tungen JE, De Souza PRS, Colas RA, Dalli J, Hansen TV, Vik A ( 2017 ) . Stereocontrolled synthesis and investigation of the biosynthetic transformations of 16(S),17(S)-epoxy-PDn-3 DPA . Org Biomol Chem vol. 15 , ( 40 ) 8606 - 8613 .

Lee S, Nakahira K, Dalli J, Siempos II, Norris PC, Colas RA, Moon J-S, Shinohara M et al. ( 2017 ) . NLRP3 Inflammasome Deficiency Protects against Microbial Sepsis via Increased Lipoxin B4Synthesis . Am J Respir Crit Care Med vol. 196 , ( 6 ) 713 - 726 .

Dakin SG, Ly L, Colas RA, Oppermann U, Wheway K, Watkins B, Dalli J, Carr AJ ( 2017 ) . Increased 15-PGDH expression leads to dysregulated resolution responses in stromal cells from patients with chronic tendinopathy . Sci Rep vol. 7 , ( 1 ) 11009 - 11009 .

Walker ME, Souza PR, Colas RA, Dalli J ( 2017 ) . 13-Series resolvins mediate the leukocyte-platelet actions of atorvastatin and pravastatin in inflammatory arthritis . FASEB Journal vol. 31 , ( 8 ) 3636 - 3648 .

Reátegui E, Jalali F, Khankhel AH, Wong E, Cho H, Lee J, Serhan CN, Dalli J et al. ( 2017 ) . Microscale arrays for the profiling of start and stop signals coordinating human-neutrophil swarming . Nature Biomedical Engineering vol. 1 , ( 7 ) 0094 - 0094 .

Hansen TV, Dalli J, Serhan CN ( 2017 ) . The Novel Lipid Mediator PD1n-3DPA: An Overview of the Structural Elucidation, Synthesis, Biosynthesis and Bioactions . Prostaglandins and Other Lipid Mediators

PERRETTI M, Dalli J, Colas R, Federici Canova D, Gobbetti T ( 2017 ) . Protectin D1n-3 DPA and resolvin D5n-3 DPA are effectors of intestinal protection . Proceedings of the National Academy of Sciences of the United States of America vol. 114 , ( 15 ) 3963 - 3968 .

China L, Maini A, Colas R, Ly L, Dalli J, Gilroy D, O'Brien A, Infection ATTIREAP ( 2017 ) . Plasma lipid mediator (LM) profiling identifies hyper- and hypo-activated groups of patients with ACLF and targeted 20% human albumin solution infusion recalibrates abnormalities . JOURNAL OF HEPATOLOGY . Conference: Hepathology vol. 66 , S390 - S390 .

Perretti M, Di Filippo C, D'Amico M, Dalli J ( 2017 ) . Characterizing the anti-inflammatory and tissue protective actions of a novel Annexin A1 peptide . PLoS One vol. 12 , ( 4 ) Article 0175786 , e0175786 - e0175786 .

Norling LV, Ly L, Dalli J ( 2017 ) . Resolving inflammation by using nutrition therapy: roles for specialized proresolving mediators . Curr Opin Clin Nutr Metab Care vol. 20 , ( 2 ) 145 - 152 .

Rathod K, Kapil V, Velmurugan S, Khambata R, Siddique U, Khan S, Gee L, Bansal J et al. ( 2017 ) . Sex differences in the inflammatory response and inflammation-induced vascular dysfunction . LANCET . Conference: FASEB vol. 389 , 20 - 20 .

Dalli J, Colas RA, Arnardottir H, Serhan CN ( 2017 ) . Vagal Regulation of Group 3 Innate Lymphoid Cells and the Immunoresolvent PCTR1 Controls Infection Resolution . Immunity vol. 46 , ( 1 ) 92 - 105 .

Freire MO, Dalli J, Serhan CN, Van Dyke TE ( 2017 ) . Neutrophil resolvin e1 receptor expression and function in type 2 diabetes . Journal of Immunology vol. 198 , ( 2 ) 718 - 728 .

Perretti M, Cooper D, Dalli J, Norling LV ( 2017 ) . Immune resolution mechanisms in inflammatory arthritis . Nat Rev Rheumatol vol. 13 , ( 2 ) 87 - 99 .

China L, Maini A, Colas R, Ly L, Dalli J, Gilroy D, O’Brien A, Group ATM ( 2017 ) . FRI-054 Plasma lipid mediator (LM) profiling identifies hyper- and hypo-activated groups of patients with ACLF and targeted 20% human albumin solution infusion recalibrates abnormalities . Journal of Hepatology vol. 66 , ( 1 )

Dalli J, Serhan C ( 2017 ) . Macrophage proresolving mediators-the when and where . Myeloid Cells in Health and Disease: A Synthesis ,

Vik A, Dalli J, Hansen TV ( 2017 ) . Recent advances in the chemistry and biology of anti-inflammatory and specialized pro-resolving mediators biosynthesized from n-3 docosapentaenoic acid . Bioorganic and Medicinal Chemistry Letters vol. 27 , ( 11 ) 2259 - 2266 .

Tsoyi K, Hall SRR, Dalli J, Colas RA, Ghanta S, Ith B, Coronata A, Fredenburgh LE et al. ( 2016 ) . Carbon Monoxide Improves Efficacy of Mesenchymal Stromal Cells during Sepsis by Production of Specialized Proresolving Lipid Mediators∗ . Critical Care Medicine vol. 44 , ( 12 ) e1236 - e1245 .

Colas RA, Dalli J, Chiang N, Vlasakov I, Sanger JM, Riley IR, Serhan CN ( 2016 ) . Identification and Actions of the Maresin 1 Metabolome in Infectious Inflammation . J Immunol vol. 197 , ( 11 ) 4444 - 4452 .

AHLUWALIA A ( 2016 ) . Accelerated resolution underlies sex differences in the inflammatory response in human . Journal of Clinical Investigation vol. 127 , ( 1 ) 169 - 182 .

Primdahl KG, Aursnes M, Walker ME, Colas RA, Serhan CN, Dalli J, Hansen TV, Vik A ( 2016 ) . Synthesis of 13(R)-Hydroxy-7Z,10Z,13R,14E,16Z,19Z Docosapentaenoic Acid (13R-HDPA) and Its Biosynthetic Conversion to the 13-Series Resolvins . J Nat Prod vol. 79 , ( 10 ) 2693 - 2702 .

Titos E, Rius B, López-Vicario C, Alcaraz-Quiles J, Garća-Alonso V, Lopategi A, Dalli J, Lozano JJ et al. ( 2016 ) . Signaling and immunoresolving actions of resolvin d1 in inflamed human visceral adipose tissue . Journal of Immunology vol. 197 , ( 8 ) 3360 - 3370 .

DALLI J ( 2016 ) . Maresin conjugates in tissue regeneration biosynthesis enzymes in human macrophages . Proceedings of the National Academy of Sciences of USA vol. 113 , ( 43 )

DALLI J, Colas RC ( 2016 ) . Human Sepsis Eicosanoid and Proresolving Lipid Mediator Temporal Profiles: Correlations With Survival and Clinical Outcomes . Critical Care Medicine

Abdulnour RE, Sham HP, Douda DN, Colas RA, Dalli J, Bai Y, Ai X, Serhan CN et al. ( 2016 ) . Aspirin-triggered resolvin D1 is produced during self-resolving gram-negative bacterial pneumonia and regulates host immune responses for the resolution of lung inflammation . Mucosal Immunology vol. 9 , ( 5 ) 1278 - 1287 .

DALLI JP ( 2016 ) . Proresolving lipid mediators resolvin D1, resolvin D2, and maresin 1 are critical in modulating T cell responses . Science Translational Medicine vol. 8 , ( 353 )

Arnardottir HH, Dalli J, Norling LV, Colas RA, Perretti M, Serhan CN ( 2016 ) . Resolvin D3 Is Dysregulated in Arthritis and Reduces Arthritic Inflammation . Journal of Immunology vol. 197 , ( 6 ) 2362 - 2368 .

Elajami TK, Colas RA, Dalli J, Chiang N, Serhan CN, Welty FK ( 2016 ) . Specialized proresolving lipid mediators in patients with coronary artery disease and their potential for clot remodeling . FASEB Journal vol. 30 , ( 8 ) 2792 - 2801 .

Colby JK, Abdulnour REE, Sham HP, Dalli J, Colas RA, Winkler JW, Hellmann J, Wong B et al. ( 2016 ) . Resolvin D3 and Aspirin-Triggered Resolvin D3 Are Protective for Injured Epithelia . American Journal of Pathology vol. 186 , ( 7 ) 1801 - 1813 .

Dalli J, Chiang N, Serhan C ( 2016 ) . AB0042 Identification of Sulfido-Conjugated Mediators That Promote Resolution of Infection and Organ Protection . Annals of the Rheumatic Diseases vol. 75 , ( Suppl 2 )

Norling L, Headland S, Dalli J, Arnardottir H, Jones H, Haworth O, Serhan C, Perretti M ( 2016 ) . PRO-RESOLVING AND CARTILAGE-PROTECTIVE ACTIONS OF RESOLVIN D1 IN INFLAMMATORY ARTHRITIS . ANNALS OF THE RHEUMATIC DISEASES . Conference: EULAR vol. 75 , 673 - 673 .

Arnardottir H, Orr SK, Dalli J, Serhan CN ( 2016 ) . Human milk proresolving mediators stimulate resolution of acute inflammation . Mucosal Immunology vol. 9 , ( 3 ) 757 - 766 .

Norling LV, Headland SE, Dalli J, Arnardottir HH, Haworth O, Jones HR, Irimia D, Serhan CN et al. ( 2016 ) . Proresolving and cartilage-protective actions of resolvin D1 in inflammatory arthritis . JCI Insight vol. 1 , ( 5 )

Dalli J ( 2016 ) . LIPID MEDIATORS AND THE RESOLUTION OF CHRONIC INFLAMMATION: IMPLICATIONS FOR ARTHRITIS THERAPY . OSTEOARTHRITIS AND CARTILAGE vol. 24 , S2 - S2 .

Ramon S, Dalli J, Sanger JM, Winkler JW, Aursnes M, Tungen JE, Hansen TV, Serhan CN ( 2016 ) . The protectin PCTR1 is produced by human M2 macrophages and enhances resolution of infectious inflammation . American Journal of Pathology vol. 186 , ( 4 ) 962 - 973 .

Wang CW, Colas RA, Dalli J, Arnardottir HH, Nguyen D, Hasturk H, Chiang N, Van Dyke TE et al. ( 2016 ) . Maresin 1 biosynthesis and proresolving anti-infective functions with human-localized aggressive periodontitis leukocytes . Infection and Immunity vol. 84 , ( 3 ) 658 - 665 .

Dalli J, Sanger JM, Rodriguez AR, Chiang N, Spur BW, Serhan CN ( 2016 ) . Identification and actions of a novel third maresin conjugate in tissue regeneration: MCTR3 . PLoS ONE vol. 11 , ( 2 )

Winkler JW, Orr SK, Dalli J, Cheng CYC, Sanger JM, Chiang N, Petasis NA, Serhan CN ( 2016 ) . Resolvin D4 stereoassignment and its novel actions in host protection and bacterial clearance . Scientific Reports vol. 6 ,

Cianci E, Recchiuti A, Trubiani O, Diomede F, Marchisio M, Miscia S, Colas RA, Dalli J et al. ( 2016 ) . Human periodontal stem cells release specialized proresolving mediators and carry immunomodulatory and prohealing properties regulated by lipoxins . Stem Cells Translational Medicine vol. 5 , ( 1 ) 20 - 32 .

Dalli J, Serhan C ( 2016 ) . Macrophage proresolving mediators-the when and where . Microbiology Spectrum vol. 4 , ( 3 )

Hansen TV, Dalli J, Serhan CN ( 2016 ) . Selective identification of specialized pro-resolving lipid mediators from their biosynthetic double di-oxygenation isomers . RSC Advances vol. 6 , ( 34 ) 28820 - 28829 .

Fiala M, Terrando N, Dalli J ( 2015 ) . Erratum: Specialized pro-resolving mediators from omega-3 fatty acids improve amyloid-β phagocytosis and regulate inflammation in patients with minor cognitive impairment (Journal of Alzheimer's Disease (2015) 48: 2 (293-301) DOI: 10.3233/JAD-150367) . Journal of Alzheimer's Disease vol. 49 , ( 4 )

Aursnes M, Tungen JE, Colas RA, Vlasakov I, Dalli J, Serhan CN, Hansen TV ( 2015 ) . Synthesis of the 16S,17S-Epoxyprotectin Intermediate in the Biosynthesis of Protectins by Human Macrophages . Journal of Natural Products vol. 78 , ( 12 ) 2924 - 2931 .

Fiala M, Terrando N, Dalli J ( 2015 ) . Specialized Pro-Resolving Mediators from Omega-3 Fatty Acids Improve Amyloid-β Phagocytosis and Regulate Inflammation in Patients with Minor Cognitive Impairment . Journal of Alzheimer's Disease vol. 48 , ( 2 ) 293 - 301 .

Dalli J, Chiang N, Serhan CN ( 2015 ) . Elucidation of novel 13-series resolvins that increase with atorvastatin and clear infections . Nature Medicine vol. 21 , ( 9 ) 1071 - 1075 .

Dalli J, Kraft BD, Colas RA, Shinohara M, Fredenburgh LE, Hess DR, Chiang N, Welty-Wolf K et al. ( 2015 ) . The regulation of proresolving lipid mediator profiles in baboon pneumonia by inhaled carbon monoxide . American Journal of Respiratory Cell and Molecular Biology vol. 53 , ( 3 ) 314 - 325 .

Chiang N, Dalli J, Colas RA, Serhan CN ( 2015 ) . Identification of resolvin D2 receptor mediating resolution of infections and organ protection . Journal of Experimental Medicine vol. 212 , ( 8 ) 1203 - 1217 .

Börgeson E, Johnson AMF, Lee YS, Till A, Syed GH, Ali-Shah ST, Guiry PJ, Dalli J et al. ( 2015 ) . Lipoxin A<inf>4</inf> Attenuates Obesity-Induced Adipose Inflammation and Associated Liver and Kidney Disease . Cell Metabolism vol. 22 , ( 1 ) 125 - 137 .

Kain V, Ingle KA, Colas RA, Dalli J, Prabhu SD, Serhan CN, Joshi M, Halade GV ( 2015 ) . Resolvin D1 activates the inflammation resolving response at splenic and ventricular site following myocardial infarction leading to improved ventricular function . Journal of Molecular and Cellular Cardiology vol. 84 , 24 - 35 .

Ramirez JL, De Almeida Oliveira G, Calvo E, Dalli J, Colas RA, Serhan CN, Ribeiro JM, Barillas-Mury C ( 2015 ) . A mosquito lipoxin/lipocalin complex mediates innate immune priming in Anopheles gambiae . Nature Communications vol. 6 ,

Dalli J, Ramon S, Norris PC, Colas RA, Serhan CN ( 2015 ) . Novel proresolving and tissue-regenerative resolvin and protectin sulfido-conjugated pathways . FASEB Journal vol. 29 , ( 5 ) 2120 - 2136 .

Serhan CN, Chiang N, Dalli J ( 2015 ) . The resolution code of acute inflammation: Novel pro-resolving lipid mediators in resolution . Seminars in Immunology vol. 27 , ( 3 ) 200 - 215 .

Amoruso A, Fresu LG, Dalli J, Miglietta D, Bardelli C, Canova DF, Perretti M, Brunelleschi S ( 2015 ) . Characterization of the anti-inflammatory properties of NCX 429, a dual-acting compound releasing nitric oxide and naproxen . Life Sciences vol. 126 , 28 - 36 .

Ramon S, Dalli J, Norris P, Colas R, Serhan C ( 2015 ) . Elucidation of Resolvin and Protectin Sulfido‐Conjugated Mediators: New Pro‐Resolving and Tissue Regenerative Pathways . The FASEB Journal vol. 29 , ( S1 )

Arnardottir H, Orr S, Dalli J, Serhan C ( 2015 ) . Human Milk Stimulates Resolution of Acute Inflammation . The FASEB Journal vol. 29 , ( S1 )

Dalli J, Chiang N, Serhan C ( 2015 ) . Novel Peptide‐Conjugated Maresins Stimulate Tissue Regeneration and Clearance of Infections in Planaria and Inflammatory Exudates . The FASEB Journal vol. 29 , ( S1 )

Winkler J, Orr S, Dalli J, Chiang N, Petasis N, Serhan C ( 2015 ) . Resolvin D4 Potent Antiiinflammatory Proresolving Actions Confirmed via Total Synthesis . The FASEB Journal vol. 29 , ( S1 )

Sulciner M, Mudge D, Ramon S, Dalli J, Kieran M, Huang S, Serhan C, Panigrahy D ( 2015 ) . Suppression of Cell Debris‐Stimulated Tumor Growth by Resolvin Mediated Clearance . The FASEB Journal vol. 29 , ( S1 )

Krishnamoorthy N, Burkett PR, Dalli J, Abdulnour REE, Colas R, Ramon S, Phipps RP, Petasis NA et al. ( 2015 ) . Cutting edge: Maresin-1 engages regulatory T cells to limit type 2 innate lymphoid cell activation and promote resolution of lung inflammation . Journal of Immunology vol. 194 , ( 3 ) 863 - 867 .

Serhan CN, Chiang N, Dalli J, Levy BD ( 2015 ) . Lipid mediators in the resolution of inflammation . Cold Spring Harbor Perspectives in Biology vol. 7 , ( 2 )

Orr SK, Colas RA, Dalli J, Chiang N, Serhan CN ( 2015 ) . Proresolving actions of a new resolvin D1 analog mimetic qualifies as an immunoresolvent . American Journal of Physiology - Lung Cellular and Molecular Physiology vol. 308 , ( 9 ) L904 - L911 .

Van Dyke TE, Hasturk H, Kantarci A, Freire MO, Nguyen D, Dalli J, Serhan CN ( 2015 ) . Proresolving nanomedicines activate bone regeneration in periodontitis . Journal of Dental Research vol. 94 , ( 1 ) 148 - 156 .

Serhan CN, Dalli J, Colas RA, Winkler JW, Chiang N ( 2015 ) . Protectins and maresins: New pro-resolving families of mediators in acute inflammation and resolution bioactive metabolome . Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids vol. 1851 , ( 4 ) 397 - 413 .

Croasdell A, Thatcher TH, Kottmann RM, Colas RA, Dalli J, Serhan CN, Sime PJ, Phipps RP ( 2015 ) . Resolvins attenuate inflammation and promote resolution in cigarette smokeexposed human macrophages . American Journal of Physiology - Lung Cellular and Molecular Physiology vol. 309 , ( 8 ) L888 - L901 .

Abdulnour REE, Dalli J, Colby JK, Krishnamoorthy N, Timmons JY, Tan SH, Colas RA, Petasis NA et al. ( 2014 ) . Maresin 1 biosynthesis during platelet-neutrophil interactions is organ-protective . Proceedings of the National Academy of Sciences of the United States of America vol. 111 , ( 46 ) 16526 - 16531 .

Shinohara M, Kibi M, Riley IR, Chiang N, Dalli J, Kraft BD, Piantadosi CA, Choi AMK et al. ( 2014 ) . Cell-Cell interactions and bronchoconstrictor eicosanoid reduction with inhaled carbon monoxide and resolvin D1 . American Journal of Physiology - Lung Cellular and Molecular Physiology vol. 307 , ( 10 ) L746 - L757 .

Dalli J, Chiang N, Serhan CN ( 2014 ) . Identification of 14-series sulfido-conjugated mediators that promote resolution of infection and organ protection . Proceedings of the National Academy of Sciences of the United States of America vol. 111 , ( 44 ) E4753 - E4761 .

Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV ( 2014 ) . Total synthesis of the anti-inflammatory and pro-resolving lipid mediator MaR1<inf>n-3 DPA</inf>utilizing an sp³-sp³Negishi cross-coupling reaction . Chemistry - A European Journal vol. 20 , ( 45 ) 14575 - 14578 .

Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV ( 2014 ) . Total synthesis of the anti-inflammatory and pro-resolving lipid mediator MaR1n-3 DPA utilizing an sp(3) -sp(3) Negishi cross-coupling reaction . Chemistry vol. 20 , ( 45 ) 14575 - 14578 .

Dalli J, Colas RA, Serhan CN ( 2014 ) . Erratum: Novel n-3 Immunoresolvents: Structures and Actions (Scientific Reports (2013) 3 DOI:10.1038/srep01940) . Scientific Reports vol. 4 ,

Tungen JE, Aursnes M, Vik A, Ramon S, Colas RA, Dalli J, Serhan CN, Hansen TV ( 2014 ) . Synthesis and anti-inflammatory and pro-resolving activities of 22-OH-PD1, a monohydroxylated metabolite of protectin D1 . Journal of Natural Products vol. 77 , ( 10 ) 2241 - 2247 .

Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV ( 2014 ) . Cover Picture: Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1n−3 DPA Utilizing an sp3–sp3 Negishi Cross‐Coupling Reaction (Chem. Eur. J. 45/2014) . Chemistry - A European Journal vol. 20 , ( 45 ) 14533 - 14533 .

Arnardottir HH, Dalli J, Colas RA, Shinohara M, Serhan CN ( 2014 ) . Aging delays resolution of acute inflammation in mice: Reprogramming the host response with novel nano-proresolving medicines . Journal of Immunology vol. 193 , ( 8 ) 4235 - 4244 .

Frediani JK, Jones DP, Tukvadze N, Uppal K, Sanikidze E, Kipiani M, Tran VT, Hebbar G et al. ( 2014 ) . Plasma metabolomics in human pulmonary tuberculosis disease: A pilot study . PLoS ONE vol. 9 , ( 10 )

Mudge D, Kieran MW, Bielenberg D, Benny O, Dalli J, Huang S, Serhan CN, Panigrahy D ( 2014 ) . Abstract 1170: Maresin 1: a potent endogenous anti-inflammatory and pro-resolving inhibitor of primary tumor growth and metastasis . Conference: Tumor Biology1170 - 1170 .

Sulciner ML, Mudge DK, Bielenberg DR, Benny O, Dalli J, Huang S, Serhan CN, Kieran MW et al. ( 2014 ) . Abstract 1664: Cancer progression: The failure to resolve . Conference: Immunology1664 - 1664 .

Tungen JE, Aursnes M, Dalli J, Arnardottir H, Serhan CN, Hansen TV ( 2014 ) . Total Synthesis of the Anti‐inflammatory and Pro‐resolving Lipid Mediator MaR1n−3 DPA Utilizing an sp3–sp3 Negishi Cross‐Coupling Reaction . Chemistry - A European Journal vol. 20 , ( 45 ) 14537 - 14537 .

Deng B, Wang CW, Arnardottir HH, Li Y, Cheng CYC, Dalli J, Serhan CN ( 2014 ) . Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages . PLoS ONE vol. 9 , ( 7 )

McCauley LK, Dalli J, Koh AJ, Chiang N, Serhan CN ( 2014 ) . Cutting edge: Parathyroid hormone facilitates macrophage efferocytosis in bone marrow via proresolving mediators resolvin d1 and resolvin D2 . Journal of Immunology vol. 193 , ( 1 ) 26 - 29 .

Colas RA, Shinohara M, Dalli J, Chiang N, Serhan CN ( 2014 ) . Identification and signature profiles for pro-resolving and inflammatory lipid mediators in human tissue . American Journal of Physiology - Cell Physiology vol. 307 , ( 1 )

Aursnes M, Tungen JE, Vik A, Dalli J, Hansen TV ( 2014 ) . ChemInform Abstract: Stereoselective Synthesis of Protectin D1: A Potent Antiinflammatory and Proresolving Lipid Mediator . ChemInform vol. 45 , ( 26 ) no - no .

Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M ( 2014 ) . 15. Neutrophils in GCA . Rheumatology (Oxford) vol. 53 , ( suppl 2 )

Serhan CN, Chiang N, Dalli J ( 2014 ) . Macrophages and the entrance of resolution phase lipid mediators . Macrophages: Biology and Role in the Pathology of Diseases ,

Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M ( 2014 ) . NEUTROPHILS IN GCA . RHEUMATOLOGY . vol. 53 , 9 - 9 .

Aursnes M, Tungen JE, Vik A, Colas R, Cheng CYC, Dalli J, Serhan CN, Hansen TV ( 2014 ) . Total synthesis of the lipid mediator PD1<inf>n-3 DPA</inf>: Configurational assignments and anti-inflammatory and pro-resolving actions . Journal of Natural Products vol. 77 , ( 4 ) 910 - 916 .

Headland S, Norling L, Patel H, Dalli J, Kelly S, Pitzalis C, Dell'Accio F, Perretti M ( 2014 ) . A novel mechanism for protecting the arthritic joint: microparticles deliver Annexin A1 into cartilage (146.8) . The FASEB Journal . vol. 28 ,

Frediani J, Jones D, Tukvadze N, Sanikidze E, Kipiani M, Uppal K, Kurani S, Hebbar G et al. ( 2014 ) . Plasma high‐resolution metabolomic profiling reveals upregulation of specific resolvins in patients with pulmonary tuberculosis (248.3) . The FASEB Journal vol. 28 , ( S1 )

Norling L, Headland S, Dalli J, Serhan C, Perretti M ( 2014 ) . Resolvin D1 protects from neutrophil mediated joint destruction in inflammatory arthritis (146.5) . The FASEB Journal . vol. 28 ,

Aursnes M, Tungen JE, Vik A, Dalli J, Hansen TV ( 2014 ) . Stereoselective synthesis of protectin D1: A potent anti-inflammatory and proresolving lipid mediator . Organic and Biomolecular Chemistry vol. 12 , ( 3 ) 432 - 437 .

Nadkarni S, Dalli J, Hollywood J, Mason JC, Dasgupta B, Perretti M ( 2014 ) . Investigational analysis reveals a potential role for neutrophils in giant-cell arteritis disease progression . Circulation Research vol. 114 , ( 2 ) 242 - 248 .

Dalli J, Norling LV, Montero-Melendez T, Canova DF, Lashin H, Pavlov AM, Sukhorukov GB, Hinds CJ et al. ( 2014 ) . Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis . EMBO Molecular Medicine vol. 6 , ( 1 ) 27 - 42 .

Mirakaj V, Dalli J, Granja T, Rosenberger P, Serhan CN ( 2014 ) . Vagus nerve controls resolution and pro-resolving mediators of inflammation . Journal of Experimental Medicine vol. 211 , ( 6 ) 1037 - 1048 .

Li Y, Dalli J, Chiang N, Baron RM, Quintana C, Serhan CN ( 2013 ) . Plasticity of leukocytic exudates in resolving acute inflammation is regulated by MicroRNA and proresolving mediators . Immunity vol. 39 , ( 5 ) 885 - 898 .

Divanovic S, Dalli J, Jorge-Nebert LF, Flick LM, Gálvez-Peralta M, Boespflug ND, Stankiewicz TE, Fitzgerald JM et al. ( 2013 ) . Contributions of the three CYP1 monooxygenases to pro-inflammatory and inflammation-resolution lipid mediator pathways . Journal of Immunology vol. 191 , ( 6 ) 3347 - 3357 .

Dalli J, Zhu M, Vlasenko NA, Deng B, Haeggström JZ, Petasis NA, Serhan CN ( 2013 ) . The novel 13S,14S-epoxy-maresinis converted by human macrophages to maresin 1 (MaR1), inhibits leukotriene A<inf>4</inf> hydrolase (LTA<inf>4</inf>H), and shifts macrophage phenotype . FASEB Journal vol. 27 , ( 7 ) 2573 - 2583 .

Sampaio ALF, Dalli J, Brancaleone V, D'Acquisto F, Perretti M, Wheatley C ( 2013 ) . Biphasic modulation of nos expression, protein and nitrite products by hydroxocobalamin underlies its protective effect in endotoxemic shock: Downstream regulation of COX-2, IL-1 β, TNF-α, IL-6, and HMGB1 expression . Mediators of Inflammation vol. 2013 ,

Chiang N, Shinohara M, Dalli J, Mirakaj V, Kibi M, Choi AMK, Serhan CN ( 2013 ) . Inhaled carbon monoxide accelerates resolution of inflammation via unique proresolving mediator-heme oxygenase-1 circuits . Journal of Immunology vol. 190 , ( 12 ) 6378 - 6388 .

Dalli J, Consalvo AP, Ray V, Filippo CD, D'Amico M, Mehta N, Perretti M ( 2013 ) . Proresolving and tissue-protective actions of annexin A1-based cleavage-resistant peptides are mediated by formyl peptide receptor 2/lipoxin A<inf>4</inf> receptor . Journal of Immunology vol. 190 , ( 12 ) 6478 - 6487 .

Dalli J, Colas RA, Serhan CN ( 2013 ) . Novel n-3 immunoresolvents: Structures and actions . Scientific Reports vol. 3 ,

Gao F, Dalli J, Claria J, Serhan CN ( 2013 ) . E. coli peritonitis initiates D‐series Resolvin‐metabolome . The FASEB Journal vol. 27 , ( S1 ) 822.9 - 822.9 .

Montero-Melendez T, Dalli J, Perretti M ( 2013 ) . Gene expression signature-based approach identifies a pro-resolving mechanism of action for histone deacetylase inhibitors . Cell Death and Differentiation vol. 20 , ( 4 ) 567 - 575 .

Shinohara M, Chiang N, Dalli J, Mirakaj V, Choi AMK, Serhan CN ( 2013 ) . Inhaled Carbon Monoxide Accelerates Resolution of Inflammation via Novel Pro‐resolving Mediators and Heme Oxygenase‐1 . The FASEB Journal vol. 27 , ( S1 ) 649.2 - 649.2 .

Dalli J, Karamnov S, Zhu M, Petasis N, Serhan CN ( 2013 ) . Maresin 1 a Novel Macrophage n‐3 Derived Mediator is a Potent Tissue Regenerative Immunoresolvent . The FASEB Journal vol. 27 , ( S1 ) 379.11 - 379.11 .

Perretti M, Dalli J, Norling LV, Melendez TM, Hinds C ( 2013 ) . Neutrophil Microparticles are heterogenous in content and function . The FASEB Journal . vol. 27 , 138.5 - 138.5 .

Dalli J, Serhan C ( 2013 ) . Pro‐Resolving Mediator Production by Human Phagocytes and their Transcellular Biosynthesis with Microparticles in Inflammation‐Resolution . The FASEB Journal vol. 27 , ( S1 ) 1168.4 - 1168.4 .

Li Y, Fredman G, Dalli J, Chiang N, Serhan CN ( 2013 ) . Temporal Regulation of Pro‐Resolving Mediators and MicroRNA in Self‐Limited versus Delayed Resolution of Acute Inflammation . The FASEB Journal vol. 27 , ( S1 ) 816.4 - 816.4 .

Dalli J, Winkler JW, Colas RA, Arnardottir H, Cheng CYC, Chiang N, Petasis NA, Serhan CN ( 2013 ) . Resolvin D3 and aspirin-triggered resolvin D3 are potent immunoresolvents . Chemistry and Biology vol. 20 , ( 2 ) 188 - 201 .

Dalli J, Montero-Melendez T, Norling LV, Yin X, Hinds C, Haskard D, Mayr M, Perretti M ( 2013 ) . Heterogeneity in neutrophil microparticles reveals distinct proteome and functional properties . Molecular and Cellular Proteomics vol. 12 , ( 8 ) 2205 - 2219 .

Norling LV, Dalli J ( 2013 ) . Microparticles are novel effectors of immunity . Current Opinion in Pharmacology vol. 13 , ( 4 ) 570 - 575 .

Jones CN, Dalli J, Dimisko L, Wong E, Serhan CN, Irimia D ( 2012 ) . Microfluidic chambers for monitoring leukocyte trafficking and humanized nano-proresolving medicines interactions . Proceedings of the National Academy of Sciences of the United States of America vol. 109 , ( 50 ) 20560 - 20565 .

Giera M, Ioan-Facsinay A, Toes R, Gao F, Dalli J, Deelder AM, Serhan CN, Mayboroda OA ( 2012 ) . Lipid and lipid mediator profiling of human synovial fluid in rheumatoid arthritis patients by means of LC-MS/MS . Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids vol. 1821 , ( 11 ) 1415 - 1424 .

Chen X, Barozzi I, Termanini A, Prosperini E, Recchiuti A, Dalli J, Mietton F, Matteoli G et al. ( 2012 ) . Requirement for the histone deacetylase Hdac3 for the inflammatory gene expression program in macrophages . Proceedings of the National Academy of Sciences of the United States of America vol. 109 , ( 42 )

Dalli J, Serhan CN ( 2012 ) . Specific lipid mediator signatures of human phagocytes: Microparticles stimulate macrophage efferocytosis and pro-resolving mediators . Blood vol. 120 , ( 15 )

Fredman G, Li Y, Dalli J, Chiang N, Serhan CN ( 2012 ) . Self-limited versus delayed resolution of acute inflammation: Temporal regulation of pro-resolving mediators and microRNA . Scientific Reports vol. 2 ,

Dalli J, Montero-Melendez T, McArthur S, Perretti M ( 2012 ) . Annexin A1 N-terminal derived peptide Ac2-26 exerts chemokinetic effects on human neutrophils . Frontiers in Pharmacology vol. 3 FEB ,

Cardini S, Dalli J, Fineschi S, Perretti M, Lungarella G, Lucattelli M ( 2012 ) . Genetic ablation of the Fpr1 gene confers protection from smoking-induced lung emphysema in mice . American Journal of Respiratory Cell and Molecular Biology vol. 47 , ( 3 ) 332 - 339 .

Clària J, Dalli J, Yacoubian S, Gao F, Serhan CN ( 2012 ) . Resolvin D1 and resolvin D2 govern local inflammatory tone in obese fat . Journal of Immunology vol. 189 , ( 5 ) 2597 - 2605 .

Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M ( 2012 ) . Resolvin D1 limits polymorphonuclear leukocyte recruitment to inflammatory loci: Receptor-dependent actions . Arteriosclerosis, Thrombosis, and Vascular Biology vol. 32 , ( 8 ) 1970 - 1978 .

Lucattelli M, Cardini S, Fineschi S, Dalli J, Perretti M, Lungarella G ( 2012 ) . FPR1 Blockade And Smoking-Induced Lung Emphysema In Mice . Conference: D80. EMPHYSEMA AND COPD: PATHOPHYSIOLOGYa6403 - a6403 .

Norling L, Dalli J, Flower R, Serhan C, Perretti M ( 2012 ) . RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS . RHEUMATOLOGY . vol. 51 , 47 - 48 .

Serhan CN, Dalli J, Karamnov S, Choi A, Park CK, Xu ZZ, Ji RR, Zhu M et al. ( 2012 ) . Macrophage proresolving mediator maresin 1 stimulates tissue regeneration and controls pain . FASEB Journal vol. 26 , ( 4 ) 1755 - 1765 .

Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M ( 2012 ) . Resolvin D1 limits PMN recruitment to inflammatory loci: receptor dependent bioactions . The FASEB Journal . vol. 26 , 835.17 - 835.17 .

Dalli J, Jones CP, Cavalcanti DM, Farsky SH, Perretti M, Rankin SM ( 2012 ) . Annexin A1 regulates neutrophil clearance by macrophages in the mouse bone marrow . FASEB Journal vol. 26 , ( 1 ) 387 - 396 .

Norling LV, Dalli J, Serhan CN, Perretti M ( 2011 ) . RESOLVIN D1 LIMITS PMN RECRUITMENT TO INFLAMMATORY LOCI: RECEPTOR DEPENDENT BIOACTIONS . INFLAMMATION RESEARCH . vol. 60 , 60 - 60 .

Brancaleone V, Dalli J, Bena S, Flower RJ, Cirino G, Perretti M ( 2011 ) . Evidence for an anti-inflammatory loop centered on polymorphonuclear leukocyte formyl peptide receptor 2/lipoxin A<inf>4</inf> receptor and operative in the inflamed microvasculature . Journal of Immunology vol. 186 , ( 8 ) 4905 - 4914 .

Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al. ( 2011 ) . Anti-inflammatory role of the murine formyl-peptide receptor 2: Ligand-specific effects on leukocyte responses and experimental in-flammation (The Journal of Immunology (2010) 184, (2611-2619)) . Journal of Immunology vol. 186 , ( 4 ) 2684 - 2685 .

Brown SM, Dalli J, Perretti M, Bush A, Davies JC, Lloyd CM ( 2011 ) . THE INFLAMMATORY RESOLUTION PROTEIN ANNEXIN A1 AND THE PAEDIATRIC CF AIRWAY . PEDIATRIC PULMONOLOGY265 - 266 .

Pederzoli-Ribeil M, Maione F, Cooper D, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F ( 2010 ) . Design and characterization of a cleavage-resistant Annexin A1 mutant to control inflammation in the microvasculature . Blood vol. 116 , ( 20 ) 4288 - 4296 .

Maderna P, Cottell DC, Toivonen T, Dufton N, Dalli J, Perretti M, Godson C ( 2010 ) . FPR2/ALX receptor expression and internalization are critical for lipoxin A4 and annexin-derived peptide-stimulated phagocytosis . FASEB J vol. 24 , ( 11 ) 4240 - 4249 .

Perretti M, Dalli J, Bolla M, Padron J ( 2010 ) . 561 THE CINOD NCX 429 INHIBITS MICROVASCULAR INFLAMMATION THROUGH ITS NO-RELEASING PROPERTIES . Osteoarthritis and Cartilage . vol. 18 ,

Renshaw D, Montero-Melendez T, Dalli J, Kamal A, Brancaleone V, D'Acquisto F, Cirino G, Perretti M ( 2010 ) . Downstream gene activation of the receptor ALX by the agonist annexin A1 . PLoS One vol. 5 , ( 9 )

Dalli J, Rosignoli G, Hayhoe RPG, Edelman A, Perretti M ( 2010 ) . CFTR Inhibition Provokes an Inflammatory Response Associated with an Imbalance of the Annexin A1 Pathway . AM J PATHOL vol. 177 , ( 1 ) 176 - 186 .

Dalli J, Rosignoli G, Hayhoe RPG, Edelman A, Perretti M ( 2010 ) . CFTR inhibition provokes an inflammatory response associated with an imbalance of the annexin A1 pathway . Am J Pathol vol. 177 , ( 1 ) 176 - 186 .

Norling LV, Dalli J, Flower RJ, Serhan CN, Perretti M ( 2010 ) . Resolvin D1 limits PMN recruitment to inflammatory loci: receptor dependent bioactions . FASEB JOURNAL vol. 24 ,

Pederzoli-Ribeil M, Maione F, Al-Kashi A, Dalli J, Perretti M, D'Acquisto F ( 2010 ) . "Super" Annexin-A1: a novel tool to regulate neutrophil-driven inflammation? . EUR J CLIN INVEST . vol. 40 , 47 - 47 .

Dufton N, Hannon R, Brancaleone V, Dalli J, Patel HB, Gray M, D'Acquisto F, Buckingham JC et al. ( 2010 ) . Anti-inflammatory role of the murine formyl-peptide receptor 2: ligand-specific effects on leukocyte responses and experimental inflammation . J Immunol vol. 184 , ( 5 ) 2611 - 2619 .

Brancaleone V, Dalli J, Perretti M ( 2010 ) . Mobilization of Annexin A1 in human polymorphonuclear leukocytes (PMN) . EUROPEAN JOURNAL OF CLINICAL INVESTIGATION . vol. 40 , 36 - 37 .

Perretti M, Dalli J ( 2009 ) . Exploiting the Annexin A1 pathway for the development of novel anti-inflammatory therapeutics . Br J Pharmacol vol. 158 , ( 4 ) 936 - 946 .

Gastardelo TS, Damazo AS, Dalli J, Flower RJ, Perretti M, Oliani SM ( 2009 ) . Functional and Ultrastructural Analysis of Annexin A1 and Its Receptor in Extravasating Neutrophils during Acute Inflammation . AM J PATHOL vol. 174 , ( 1 ) 177 - 183 .

Dalli J, Norling LV, Renshaw D, Cooper D, Leung K-Y, Perretti M ( 2008 ) . Annexin 1 mediates the rapid anti-inflammatory effects of neutrophil-derived microparticles . Blood vol. 112 , ( 6 ) 2512 - 2519 .

Gavins FNE, Dalli J, Flower RJ, Granger DN, Perretti M ( 2007 ) . Activation of the annexin 1 counter-regulatory circuit affords protection in the mouse brain microcirculation . FASEB J vol. 21 , ( 8 ) 1751 - 1758 .

Renshaw D, Dalli J, Kamal A, Perretti M ( 2006 ) . Disinct patterns of gene expression induced by annexin 1 activation of the ALXR receptor in HEK293 cells . FASEB JOURNAL . vol. 20 , A646 - A646 .

Renshaw D, Sawmynadan P, Dalli J, Perretti M ( 2006 ) . Glueocorticoid regulated expression of the anti-inflammatory receptor ALXR . FASEB JOURNAL . vol. 20 , A645 - A645 .