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Research

Publications: Dr Karin Hing

Zhou B, Jiang Y, Guo Q, Das A, Jorge Sobrido A, Hing K, Zayats A, Krause S ( 2022 ) . Photoelectrochemical Detection of Calcium Ions Based on Hematite Nanorod Sensors . ACS Applied Nano Materials
Kohnken-Sawall J, Rawlinson SCF, Hing KA ( 2022 ) . OSTEOGENIC ACTIVITY OF ACTIFUSE (TM) IS NOT ENHANCED BY PRE-ADSORBED BMP2 . TISSUE ENGINEERING PART A . vol. 28 , S42 - S42 .
Zhou B, Das A, Zhong M, Guo Q, Zhang DW, Hing KA, Sobrido AJ, Titirici MM et al. ( 2021 ) . Photoelectrochemical imaging system with high spatiotemporal resolution for visualizing dynamic cellular responses . Biosensors and Bioelectronics vol. 180 ,
Hexter AT, Hing KA, Haddad FS, Blunn G ( 2020 ) . Decellularized porcine xenograft for anterior cruciate ligament reconstruction: A histological study in sheep comparing cross-pin and cortical suspensory femoral fixation . Bone and Joint Research vol. 9 , ( 6 ) 293 - 301 .
Wu F, Zhou B, Wang J, Zhong M, Das A, Watkinson M, Hing K, Zhang D-W et al. ( 2019 ) . Photoelectrochemical Imaging System for the Mapping of Cell Surface Charges . Anal Chem
Mafina MK, Sullivan AC, Hing KA ( 2017 ) . Use of a fluorescent probe to monitor the enhanced affinity of rh-BMP-2 to silicated-calcium phosphate synthetic bone graft substitutes under competitive conditions . Materials Science and Engineering C vol. 80 , 207 - 212 .
Sriranganathan D, Chen X, Hing KA, Kanwal N, Hill RG ( 2017 ) . The effect of the incorporation of fluoride into strontium containing bioactive glasses . Journal of Non-Crystalline Solids vol. 457 , 25 - 30 .
Campion C, Hing KA ( 2016 ) . Porous Bone Graft Substitutes: When Less is More . Mechanobiology: Exploitation for Medical Benefit ,
Sriranganathan D, Kanwal N, Hing KA, Hill RG ( 2016 ) . Strontium substituted bioactive glasses for tissue engineered scaffolds: the importance of octacalcium phosphate . Journal of Materials Science: Materials in Medicine vol. 27 , ( 2 ) 1 - 10 .
Coathup MJ, Blunn GW, Campion C, Ho C-Y, Hing KA ( 2016 ) . The effect of increased microporosity on bone formation within silicate-substituted scaffolds in an ovine posterolateral spinal fusion model . J Biomed Mater Res B Appl Biomater vol. 105 , ( 4 ) 805 - 814 .
Hutchens SA, Campion C, Assad M, Chagnon M, Hing KA ( 2015 ) . Efficacy of silicate-substituted calcium phosphate with enhanced strut porosity as a standalone bone graft substitute and autograft extender in an ovine distal femoral critical defect model . J Mater Sci Mater Med vol. 27 , ( 1 ) 20 - 20 .
Shah FA, Brauer DS, Hill RG, Hing KA ( 2015 ) . Apatite formation of bioactive glasses is enhanced by low additions of fluoride but delayed in the presence of serum proteins . Materials Letters vol. 153 , 143 - 147 .
Shah FA, Brauer DS, Desai N, Hill RG, Hing KA ( 2014 ) . Fluoride-containing bioactive glasses and Bioglass<sup>®</sup> 45S5 form apatite in low pH cell culture medium . Materials Letters vol. 119 , 96 - 99 .
Shah FA, Brauer DS, Wilson RM, Hill RG, Hing KA ( 2014 ) . Influence of cell culture medium composition on in vitro dissolution behavior of a fluoride-containing bioactive glass . Journal of Biomedical Materials Research - Part A vol. 102 , ( 3 ) 647 - 654 .
Castagna V, Olivares-Navarrete R, Schwartz Z, Boyan BD, Hing KA ( 2013 ) . HMSC proliferation and differentiation are dependent on chemistry and surface roughness of calcium phosphate bone substitutes . European Cells and Materials vol. 26 , ( SUPPL. 3 )
Campion CR, Ball SL, Clarke DL, Hing KA ( 2013 ) . Microstructure and chemistry affects apatite nucleation on calcium phosphate bone graft substitutes . Journal of Materials Science: Materials in Medicine vol. 24 , ( 3 ) 597 - 610 .
Mafina M-K, Hing KA, Sullivan AC ( 2013 ) . Development of novel fluorescent probes for the analysis of protein interactions under physiological conditions with medical devices . Langmuir vol. 29 , ( 5 ) 1420 - 1426 .
Hing KA ( 2013 ) . 8 Biomimetic bone regeneration . Biomimetic Biomaterials ,
Ghani Y, Coathup MJ, Hing KA, Blunn GW ( 2013 ) . Antibacterial effect of incorporating silver ions in electrochemically deposited hydroxyapatite coating: An experimental study . JRSM Short Rep vol. 4 , ( 9 )
Hing KA ( 2013 ) . Biomimetic bone regeneration . 207 - 237 .
Ruys A, Tampieri A, Sprio S, Ehrlich H, Rabiei R, Dastjerdi AK, Mirkhalaf M, Barthelat F et al. ( 2013 ) . Contributor contact details . Biomimetic Biomaterials ,
Campion R, Ball S, Clarke D, Hing K ( 2012 ) . Microstructure and chemistry affects the in vitro bioactivity of calcium phosphate bone graft substitutes . JOURNAL OF TISSUE ENGINEERING AND REGENERATIVE MEDICINE . vol. 6 , 232 - 232 .
Coathup MJ, Hing KA, Samizadeh S, Chan O, Fang YS, Campion C, Buckland T, Blunn GW ( 2012 ) . Effect of increased strut porosity of calcium phosphate bone graft substitute biomaterials on osteoinduction . Journal of Biomedical Materials Research - Part A vol. 100 A , ( 6 ) 1550 - 1555 .
Ghani Y, Coathup MJ, Hing KA, Blunn GW ( 2012 ) . Development of a hydroxyapatite coating containing silver for the prevention of peri-prosthetic infection . J Orthop Res vol. 30 , ( 3 ) 356 - 363 .
Ozad U, Parish A, Hing KA ( 2012 ) . Bioactivity And Bone Formation In Silicon-Substituted Hydroxyapatite . Sakarya University Journal of Science vol. 16 , ( 3 ) 170 - 177 .
Chan O, Coathup MJ, Nesbitt A, Ho CY, Hing KA, Buckland T, Campion C, Blunn GW ( 2012 ) . The effects of microporosity on osteoinduction of calcium phosphate bone graft substitute biomaterials . Acta Biomaterialia vol. 8 , ( 7 ) 2788 - 2794 .
Coathup MJ, Samizadeh S, Fang YS, Buckland T, Hing KA, Blunn GW ( 2011 ) . The osteoinductivity of silicate-substituted calcium phosphate . J Bone Joint Surg Am vol. 93 , ( 23 ) 2219 - 2226 .
Castagna V, Sullivan A, Hing K ( 2011 ) . Fibronectin adsorption to stoichiometric and silicate substituted hydroxyapatite sensitive to FN concentration and presence of serum proteins . 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials
Parish A, Davis G, Hing K ( 2011 ) . The quantitative and qualitative analysis bone ingrowth network quality of hydroxyapatite implants over time to investigate the process of internal bone growth via novel automated 3D image processing . 24th European Conference on Biomaterials - Annual Conference of the European Society for Biomaterials
Guth K, Campion C, Buckland T, Hing KA ( 2011 ) . Effects of serum protein on ionic exchange between culture medium and microporous hydroxyapatite and silicate-substituted hydroxyapatite . Journal of Materials Science: Materials in Medicine vol. 22 , ( 10 ) 2155 - 2164 .
Campion CR, Chander C, Buckland T, Hing K ( 2011 ) . Increasing strut porosity in silicate-substituted calcium-phosphate bone graft substitutes enhances osteogenesis . Journal of Biomedical Materials Research - Part B Applied Biomaterials vol. 97 B , ( 2 ) 245 - 254 .
Parish AJB, Davis GR, Hing KA ( 2011 ) . Automated computation of 3D histomorphometry within implanted hydroxyapatite porous scaffolds . European Cells and Materials vol. 22 , ( SUPPL.2 )
Castagna V, Sullivan A, Hing KA ( 2011 ) . Behaviour of fibronectin on interaction with stoichiometric and silicate substituted hydroxyapatite bone graft substitiutes . European Cells and Materials vol. 22 , ( SUPPL.2 )
Mafina MK, Sullivan AC, Hing KA ( 2011 ) . Recording and evaluating the effect of silicon-substitution on protein adsorption/desorption to hydroxyapatite . European Cells and Materials vol. 22 , ( SUPPL.2 )
Hing K ( 2010 ) . Tissue engineering . MATER WORLD vol. 18 , ( 9 ) 28 - 30 .
Guth K, Campion C, Buckland T, Hing KA ( 2010 ) . Surface physiochemistry affects protein adsorption to stoichiometric and silicate-substituted microporous hydroxyapatites . Advanced Engineering Materials vol. 12 , ( 4 )
Guth K, Campion C, Buckland T, Hing KA ( 2010 ) . Effect of silicate-substitution on attachment and early development of human osteoblast-like cells seeded on microporous hydroxyapatite discs . Advanced Engineering Materials vol. 12 , ( 1-2 )
Mafina MK, Sullivan AC, Hing KA ( 2009 ) . Monitoring the effect of silicate substitution on protein adsorption/desorption to hydroxyapatite . European Cells and Materials vol. 18 , ( SUPPL. 2 )
HING KA, Bonfield W ( 2009 ) . foamed ceramics . no. US 12/216,710 ,
Samizadeh S, Amogbokpa J, Fang SC, Coathup MJ, Hing KA, Buckland T, Blunn GW ( 2008 ) . Osseoinduction by calcium phosphate bone substitutes is a function of chemical composition and structure . 8th World Biomaterials Congress 2008 vol. 2 ,
Hing KA ( 2008 ) . Biomaterials - Where biology, physics, chemistry, engineering and medicine meet . Journal of Physics: Conference Series vol. 105 , ( 1 )
Hing KA ( 2008 ) . Biomaterials - Where Biology, Physics, Chemistry, Engineering and Medicine meet . ENGINEERING AND PHYSICS - SYNERGY FOR SUCCESS . vol. 105 ,
Christophy C, Rashid N, Di Silvio L, Hing KA ( 2008 ) . Encouraging nature with ceramics: The roles of surface roughness and physio-chemistry on cell response to substituted apatites . CIMTEC 2008 - Proceedings of the 3rd International Conference on Smart Materials, Structures and Systems - Biomedical Applications of Smart Materials, Nanotechnology and Micro/Nano Engineering . vol. 57 , 22 - 30 .
Rashid N, Harding I, Buckland T, HING KA ( 2008 ) . Nano-scale manipulation of silicate-substituted apatite chemistry impacts surface charge, hydrophilicity, protein adsorption and cell attachment . International Journal of Nano and Biomaterials vol. 1 , ( 3 ) 299 - 319 .
Hing KA, Wilson LF, Buckland T ( 2007 ) . Comparative performance of three ceramic bone graft substitutes . Spine J vol. 7 , ( 4 ) 475 - 490 .
Mabilleau G, Xia Z, Hing KA, Buckland T, Sabokbar A ( 2007 ) . Osteoclastic responses to phase pure hydroxyapatite (HA) and silicon (SI)-substituted HA . TISSUE ENGINEERING . vol. 13 , 1388 - 1388 .
De Carlos A, Lusquinos F, Pou J, Leon B, Perez-Amor M, Driessens FCM, Hing K, Best S et al. ( 2006 ) . In vitro testing of Nd : YAG laser processed calcium phosphate coatings . JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE . vol. 17 , 1153 - 1160 .
Hing KA, Revell PA, Smith N, Buckland T ( 2006 ) . Effect of silicon level on rate, quality and progression of bone healing within silicate-substituted porous hydroxyapatite scaffolds . Biomaterials vol. 27 , ( 29 ) 5014 - 5026 .
De Carlos A, Lusquinos F, Pou J, Leon B, Perez-Amor M, Driessens FCM, HING KA, Best S et al. ( 2006 ) . In vitro testing of Nd : YAG laser processed calcium phosphate coatings . Journal of Materials Science Materials in Medicine vol. 17 , ( 11 ) 1153 - 1160 .
Guth K, Buckland T, Hing KA ( 2006 ) . Silicon dissolution from microporous silicon substituted hydroxyapatite and its effect on osteoblast behaviour . BIOCERAMICS 18, PTS 1 AND 2 . Editors: Nakamura, T, Yamashita, K, Neo, M , vol. 309-311 , 117 - 120 .
Harding IS, Rashid N, Hing KA ( 2005 ) . Surface charge and the effect of excess calcium ions on the hydroxyapatite surface . Biomaterials vol. 26 , ( 34 ) 6818 - 6826 .
Mehta JS, Futter CE, Sandeman SR, Faragher RGAF, Hing KA, Tanner KE, Allan BDS ( 2005 ) . Hydroxyapatite promotes superior keratocyte adhesion and proliferation in comparison with current keratoprosthesis skirt materials . BRIT J OPHTHALMOL vol. 89 , ( 10 ) 1356 - 1362 .
Hing KA, Annaz B, Saeed S, Revell PA, Buckland T ( 2005 ) . Microporosity enhances bioactivity of synthetic bone graft substitutes . JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE . vol. 16 , 467 - 475 .
Hing KA ( 2005 ) . Bioceramic bone graft substitutes: Influence of porosity and chemistry . INT J APPL CERAM TEC vol. 2 , ( 3 ) 184 - 199 .
HING KA, Annaz B, Saeed S, Revell PA, Buckland T ( 2005 ) . Microporosity enhances bioactivity of synthetic bone graft substitutes . Journal of Materials Science Materials in Medicine vol. 16 , ( 5 ) 467 - 475 .
Hing KA ( 2004 ) . Bone repair in the twenty-first century: biology, chemistry or engineering? . Philos Trans A Math Phys Eng Sci vol. 362 , ( 1825 ) 2821 - 2850 .
Hing KA, Saeed S, Annaz B, Buckland T, Revell PA ( 2004 ) . Bone development is sensitive to silicon level in substituted apatites . Transactions - 7th World Biomaterials Congress
Rashid N, Harding I, Hing KA ( 2004 ) . Effect of silicate substitution on the surface charge of hydroxyapatite . Transactions - 7th World Biomaterials Congress
Saeed S, Hing K, Revell PA ( 2004 ) . HA activates T cells and causes inflammation in liver and spleen from rabbits following intraosseous implantation . Transactions - 7th World Biomaterials Congress
Hing KA, Saeed S, Annaz B, Buckland T, Revell PA ( 2004 ) . Microporosity enhances bioactivity of synthetic bone graft substitutes . Transactions - 7th World Biomaterials Congress
Annaz B, Hing KA, Kayser M, Buckland T, Di Silvio L ( 2004 ) . The role of microporosity in synthetic porous ceramics . Transactions - 7th World Biomaterials Congress
Annaz B, Hing KA, Kayser M, Buckland T, Di Silvio L ( 2004 ) . An ultrastructural study of cellular response to variation in porosity in phase-pure hydroxyapatite . J Microsc vol. 216 , ( Pt 2 ) 97 - 109 .
Annaz B, Hing KA, Kayser M, Buckland T, Di Silvio L ( 2004 ) . Porosity variation in hydroxyapatite and osteoblast morphology: a scanning electron microscopy study . J Microsc vol. 215 , ( Pt 1 ) 100 - 110 .
Hing KA, Best SM, Tanner KE, Bonfield W, Revell PA ( 2004 ) . Mediation of bone ingrowth in porous hydroxyapatite bone graft substitutes . J Biomed Mater Res A vol. 68 , ( 1 ) 187 - 200 .
HING KA, Tanner KE, Best SM, Bonfield W, Revell PA ( 2004 ) . Mediation of bone ingrowth in porous hydroxyaptite bone graft substitutes . Journal of Biomedical Materials Research vol. 68A , 187 - 200 .
Hing KA, Saeed S, Annaz B, Buckland T, Revell PA ( 2004 ) . Microporosity affects bioactivity of macroporous hydroxyapatite bone graft substitutes . BIOCERAMICS 16 . Editors: Barbosa, MA, Monteiro, FJ, Correia, R, Leon, B et al. , vol. 254-2 , 273 - 276 .
HING KA, Revell PA, McInness T, Damien E ( 2004 ) . Novel Bioceramic Foams For Bone Grafting . Journal of Bone & Joint Surgery - British Volume vol. 86-B Suppl I:II ,
Damien E, Hing K, Saeed S, Revell PA ( 2003 ) . A preliminary study on the enhancement of the osteointegration of a novel synthetic hydroxyapatite scaffold in vivo . J Biomed Mater Res A vol. 66 , ( 2 ) 241 - 246 .
Lusquiños F, De Carlos A, Pou J, Arias JL, Boutinguiza M, León B, Pérez-Amor M, Driessens FCM et al. ( 2003 ) . Calcium phosphate coatings obtained by Nd:YAG laser cladding: physicochemical and biologic properties . J Biomed Mater Res A vol. 64 , ( 4 ) 630 - 637 .
Patel N, Best SM, Bonfield W, Gibson IR, Hing KA, Damien E, Revell PA ( 2002 ) . A comparative study on the in vivo behavior of hydroxyapatite and silicon substituted hydroxyapatite granules . J Mater Sci Mater Med vol. 13 , ( 12 ) 1199 - 1206 .
Ke S, Gibson IR, Hing KA ( 2002 ) . Characterisation of mono- and biphasic calcium phosphates granules . BIOCERAMICS 14 . Editors: Brown, S, Clarke, I, Williams, P , vol. 218-2 , 625 - 628 .
Gibson IR, Hing KA, Revell PA, Santos JD, Best SM, Bonfield W ( 2002 ) . Enhanced in vivo response to silicate-substituted hydroxyapatite . BIOCERAMICS 14 . Editors: Brown, S, Clarke, I, Williams, P , vol. 218-2 , 203 - 206 .
Abdullah Y, Yusof MR, Besar I, Mustafa R, Hing KA ( 2002 ) . Fabrication of porous hydroxyapatite by foam technique . EURO CERAMICS VII, PT 1-3 . vol. 206-2 , 1543 - 1546 .
Patel N, Gibson IR, Hing KA, Best SM, Damien E, Revell PA, Bonfield W ( 2002 ) . The in vivo response of phase pure hydroxyapatite and carbonate substituted hydroxyapatite granules of varying size ranges . BIOCERAMICS 14 . Editors: Brown, S, Clarke, I, Williams, P , vol. 218-2 , 383 - 386 .
Damien E, MacInnes T, Hing K, Revell PA ( 2001 ) . Insulin like growth factor (IGF-I) increases the bioactivity of porous hydroxyapatite (PHA) in vivo in rabbits . J PATHOL vol. 193 , 6A - 6A .
Hing KA, Gibson IR, Revell PA, Best SM, Bonfield W ( 2000 ) . Influence of phase purity on the in vivo response to hydroxyapatite . BIOCERAMICS . Editors: Giannini, S, Moroni, A , vol. 192-1 , 373 - 376 .
Patel N, Best SM, Gibson IR, Ke S, Hing KA, Bonfield W ( 2000 ) . Preparation and characterisation of hydroxyapatite and carbonate substituted hydroxyapatite granules . BIOCERAMICS . Editors: Giannini, S, Moroni, A , vol. 192-1 , 7 - 10 .
Huang J, Hing KA, Best SM, Lee DA, Silvio LD, Bonfield W ( 1999 ) . A COMPARATIVE STUDY OF VARIOUS ASSAYS FOR IN VITRO BIOCOMPATIBILITY ASSESSMENT OF EXPERIMENTAL ZIRCONIA . Conference: Bioceramics199 - 202 .
Hing KA, Merry JC, Gibson IR, Di-Silvio L, Best SM, Bonfield W ( 1999 ) . EFFECT OF CARBONATE CONTENT ON THE RESPONSE OF HUMAN OSTEOBLAST-LIKE CELLS TO CARBONATE SUBSTITUTED HYDROXYAPATITE . Conference: Bioceramics195 - 198 .
Parsons NS, Hing KA, Buckland T, Best SM, Bonfield W ( 1999 ) . PHYSICAL PROPERTIES OF A NOVEL GLASS-CERAMIC-REINFORCED HYRDROXYAPATITE COMPOSITE . Conference: Bioceramics413 - 416 .
Hing KA, Best SM, Tanner KE, Bonfield W, Revell PA ( 1999 ) . Quantification of bone ingrowth within bone-derived porous hydroxyapatite implants of varying density . J Mater Sci Mater Med vol. 10 , ( 10/11 ) 663 - 670 .
Hing KA, Best SM, Bonfield W ( 1999 ) . Characterization of porous hydroxyapatite . J Mater Sci Mater Med vol. 10 , ( 3 ) 135 - 145 .
Di Silvio L, Hing K, Bonfield W ( 1999 ) . Macroporous hydroxyapatites: Potential drug delivery systems . Proceedings of the Controlled Release Society ( 26 ) 1152 - 1153 .
Hing K, Knight M ( 1998 ) . Prize-winning peeks at the microscopic world .
Di Silvio L, Hing K, Bonfield W ( 1998 ) . A degradable drug delivery system for orthopaedic application . NEW BIOMEDICAL MATERIALS . Editors: Haris, PI, Chapman, D , vol. 16 , 125 - 129 .
Hing KA, Best SM, Tanner KE, Revell PA, Bonfield W ( 1998 ) . Histomorphological and biomechanical characterization of calcium phosphates in the osseous environment . Proc Inst Mech Eng H vol. 212 , ( 6 ) 437 - 451 .
Hing KA, Best SM, Tanner KE, Bonfield W, Revell PA ( 1997 ) . Biomechanical assessment of bone ingrowth in porous hydroxyapatite . J Mater Sci Mater Med vol. 8 , ( 12 ) 731 - 736 .
Lopes MA, Knowles JC, Hing KA, Santos JD, Monteiro FJ, Olsen I ( 1997 ) . Biological evaluation of glass reinforced hydroxyapatite by flow cytometry . BIOCERAMICS, VOL 10 . Editors: Sedel, L, Rey, C , 575 - 578 .
Hing KA, Di Silvio L, Gibson IR, Ohtsuki C, Jha LJ, Best SM, Bonfield W ( 1997 ) . Effect of fluoride substitution on the biocompatibility of hydroxyapatite . BIOCERAMICS, VOL 10 . Editors: Sedel, L, Rey, C , 19 - 22 .
Revell PA, Hing KA, Tanner KE, Best SM, Bonfield W ( 1997 ) . Osseointegration of porous hydroxyapatite . BONE GRAFT SUBSTITUTES AND GROWTH FACTORS . Editors: Schnettler, R, Markgraf, E , 28 - 30 .
Hing KA, Best SM, Revell PA, Tanner KE, Bonfield W ( 1996 ) . Histomorphometric and biomechanical assessment of bone ingrowth in porous hydroxyapatite . Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium vol. 2 ,
HING KA ( 1996 ) . Assessment of porous hydroxyapatite for bone replacement . Supervisors: Best, SM, Bonfield, W , Presented at: Queen Mary University of London ,