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Research

Publications: Miss Belinda Nedjai

Adcock R, Nedjai B, Lorincz AT, Scibior-Bentkowska D, Banwait R, Torrez-Martinez N, Robertson M, Cuzick J et al. ( 2022 ) . DNA methylation testing with S5 for triage of high-risk HPV positive women . International Journal of Cancer vol. 151 , ( 7 ) 993 - 1004 .
Dickey BL, Nedjai B, Preece MD, Schell MJ, Boulware D, Whiting J, Sirak B, Abrahamsen M et al. ( 2022 ) . Methylation of HPV16 and EPB41L3 in oral gargles and the detection of early and late oropharyngeal cancer . Cancer Medicine vol. 11 , ( 20 ) 3735 - 3742 .
Banila C, Lorincz AT, Scibior-Bentkowska D, Clifford GM, Kumbi B, Beyene D, Wheeler CM, Cuschieri K et al. ( 2022 ) . Clinical performance of methylation as a biomarker for cervical carcinoma in situ and cancer diagnosis: A worldwide study . International Journal of Cancer vol. 150 , ( 2 ) 290 - 302 .
Humphrey HN, Diodato A, Isner JC, Walker E, Lacy-Colson J, Nedjai B, Daniels IR, McDermott FD et al. ( 2022 ) . An internal pilot study of a novel rectal mucocellular sampling device to allow next-generation sequencing for colorectal disease . Techniques in Coloproctology
Lehtinen M, Pimenoff VN, Nedjai B, Louvanto K, Verhoef L, Heideman DAM, El-Zein M, Widschwendter M et al. ( 2022 ) . Assessing the risk of cervical neoplasia in the post-HPV vaccination era . International Journal of Cancer
Hurt CN, Nedjai B, Alvarez-Mendoza C, Powell N, Tristram A, Jones S ( 2022 ) . Combined HPV 16 E2 and L1 methylation predict response to treatment with cidofovir and imiquimod in patients with vulval intraepithelial neoplasia . Cancer biomarkers : section A of Disease markers vol. 35 , ( 2 ) 143 - 153 .
Hernandez-Lopez R, Hermosillo L, Leon-Maldonado L, Velázquez-Cruz R, Torres-Ibarra L, Lazcano-Ponce E, Lorincz A, Wheeler CM et al. ( 2021 ) . Performance of an affordable urine selfsampling method for human papillomavirus detection in Mexican women . PLoS ONE vol. 16 , ( 7 July )
Nyitray AG, Schick V, Swartz MD, Giuliano AR, Fernandez ME, Deshmukh AA, Ridolfi TJ, Ajala C et al. ( 2021 ) . Rationale and design of the Prevent Anal Cancer Self-Swab Study: a protocol for a randomised clinical trial of home-based self-collection of cells for anal cancer screening . BMJ Open vol. 11 , ( 6 )
Cadman L, Reuter C, Jitlal M, Kleeman M, Austin J, Hollingworth T, Parberry AL, Ashdown-Barr L et al. ( 2021 ) . A randomized comparison of different vaginal self-sampling devices and urine for human papillomavirus testing-predictors 5.1 . Cancer Epidemiology Biomarkers and Prevention vol. 30 , ( 4 ) 661 - 668 .
Reuter C, Preece M, Banwait R, Boer S, Cuzick J, Lorincz A, Nedjai B ( 2021 ) . Consistency of the S5 DNA methylation classifier in formalin-fixed biopsies versus corresponding exfoliated cells for the detection of pre-cancerous cervical lesions . Cancer Medicine vol. 10 , ( 8 ) 2668 - 2679 .
Ramírez AT, Sánchez GI, Nedjai B, Agudelo MC, Brentnall A, Cuschieri K, Castañeda KM, Cuzick J et al. ( 2020 ) . Effective methylation triage of HPV positive women with abnormal cytology in a middle- 2 income country . International Journal of Cancer
Giuliano AR, Nedjai B, Lorincz AT, Schell MJ, Rahman S, Banwait R, Boulware D, Sirak B et al. ( 2020 ) . Methylation of HPV 16 and EPB41L3 in oral gargles: Associations with oropharyngeal cancer detection and tumor characteristics . International Journal of Cancer vol. 146 , ( 4 ) 1018 - 1030 .
Nedjai B, Hernández-López R, Lorincz A, Torres-Ibarra L, Reuter C, Scibior-Bentkowska D, Warman R, Mendiola-Pastrana I et al. ( 2019 ) . Methylation estimates the risk of precancer in HPV-infected women with discrepant results between cytology and HPV16/18 genotyping . Clinical Epigenetics
Banila C, Nedjai B, Reuter C, Cuschieri K, Clifford G, Lorincz A ( 2019 ) . 77 Cervical pre-cancer vs invasive cancer: molecular differentiation with potential of improving cervical cancer screening worldwide . International Journal of Gynecological Cancer . Conference: E-Poster discussions vol. 29 ,
Louvanto K, Aro K, Nedjai B, Bützow R, Jakobsson M, Kalliala I, Dillner J, Nieminen P et al. ( 2019 ) . Methylation in predicting progression of untreated high-grade cervical intraepithelial neoplasia . Clinical Infectious Diseases
Cuschieri K, Lorincz AT, Nedjai B ( 2019 ) . Human Papillomavirus Research: Where Should We Place Our Bets? . Acta Cytol vol. 63 , ( 2 ) 85 - 96 .
Nedjai B, Reuter C, Ahmad A, Banwait R, Warman R, Carton J, Boer S, Cuzick J et al. ( 2018 ) . Molecular progression to cervical precancer, epigenetic switch or sequential model? . International Journal of Cancer vol. 143 , ( 7 ) 1720 - 1730 .
Bagnati M, Ogunkolade BW, Marshall C, Tucci C, Hanna K, Jones TA, Bugliani M, Nedjai B et al. ( 2016 ) . Glucolipotoxicity initiates pancreatic β-cell death through TNFR5/CD40-mediated STAT1 and NF-κB activation . Cell Death and Disease vol. 7 , ( 8 )
Nedjai B, Viney JM, Li H, Hull C, Anderson CA, Horie T, Horuk R, Vaidehi N et al. ( 2015 ) . CXCR3 antagonist VUF10085 binds to an intrahelical site distinct from that of the broad spectrum antagonist TAK-779 . British Journal of Pharmacology vol. 172 , ( 7 ) 1822 - 1833 .
Turner MD, Nedjai B, Hurst T, Pennington DJ ( 2014 ) . Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease . Biochimica et Biophysica Acta - Molecular Cell Research vol. 1843 , ( 11 ) 2563 - 2582 .
Bybee A, Lachmann H, Omoyinmi E, Nedjai B, Woo P, Lane T, Savic S, Hawkins P et al. ( 2013 ) . PW02-031 - Genetic and clinical manifestations of CAPS . Pediatric Rheumatology vol. 11 , ( Suppl 1 )
Nedjai B, Li H, Stroke IL, Wise EL, Webb ML, Merritt JR, Henderson I, Klon AE et al. ( 2012 ) . Small molecule chemokine mimetics suggest a molecular basis for the observation that CXCL10 and CXCL11 are allosteric ligands of CXCR3 . British Journal of Pharmacology vol. 166 , ( 3 ) 912 - 923 .
Turner MD, Chaudhry A, Nedjai B ( 2012 ) . Tumour necrosis factor receptor trafficking dysfunction opens the TRAPS door to pro-inflammatory cytokine secretion . Bioscience Reports vol. 32 , ( 2 ) 105 - 112 .
Nedjai B, Hitman GA, Church LD, Minden K, Whiteford ML, McKee S, Stjernberg S, Pettersson T et al. ( 2011 ) . Differential cytokine secretion results from p65 and c-Rel NF-κB subunit signaling in peripheral blood mononuclear cells of TNF receptor-associated periodic syndrome patients . Cellular Immunology vol. 268 , ( 2 ) 55 - 59 .
Nedjai B, Quillinan N, Coughlan RJ, Church L, McDermott MF, Hitman GA, Turner MD ( 2010 ) . Lessons from anti-TNF biologics: infliximab failure in a TRAPS family with the T50M mutation in TNFRSF1A . Advances in Tnf Family Research; Proceedings from the 12th International TNF Conference, 2009. , Editors: Wallach, D, Kovalenko, A, Feldmann, M , vol. 691 , Springer ( New York ),
Hall SE, Mao A, Nicolaidou V, Finelli M, Wise EL, Nedjai B, Kanjanapangka J, Harirchian P et al. ( 2009 ) . Elucidation of binding sites of dual antagonists in the human chemokine receptors CCR2 and CCR5 . Molecular Pharmacology vol. 75 , ( 6 ) 1325 - 1336 .
Nedjai B, Hitman GA, Quillinan N, Coughlan RJ, Church L, McDermott MF, Turner MD ( 2009 ) . Proinflammatory action of the antiinflammatory drug infliximab in tumor necrosis factor receptor-associated periodic syndrome . Arthritis and Rheumatism vol. 60 , ( 2 ) 619 - 625 .
Churchman SM, Church LD, Savic S, Coulthard LR, Hayward B, Nedjai B, Turner MD, Mathews RJ et al. ( 2008 ) . A novel TNFRSF1A splice mutation associated with increased nuclear factor kappa appaB (NF-kappa B) transcription factor activation in patients with tumour necrosis factor receptor associated periodic syndrome (TRAPS) . ANN RHEUM DIS vol. 67 , ( 11 ) 1589 - 1595 .
Turner MD, Nedjai B, Hitman GA, McDermott M ( 2008 ) . Cell surface expression of TNFRI in tumor necrosis factor receptor-associated periodic syndrome: comment on the article by Nedjai et al - Reply . ARTHRITIS RHEUM vol. 58 , ( 7 ) 2214 - 2215 .
Nedjai B, Hitman G, Yousaf N, Chernajovsky Y, Stjernberg-Salmela S, Pettersson T, Ranki A, Hawkins P et al. ( 2008 ) . Abnormal TNFR1 cell surface expression and NF-kappaB activation in TNFR1-Associated Periodic Fever Syndrome (TRAPS) . CLIN EXP RHEUMATOL vol. 26 , ( 2 ) 182 - 182 .
Nedjai B, Hitman GA, Yousaf N, Chernajovsky Y, Stiernberg-Salmela S, Pettersson T, Ranki A, Hawkins PN et al. ( 2008 ) . Abnormal tumor necrosis factor receptor I cell surface expression and NF-kappa B activation in tumor necrosis factor receptor-associated periodic syndrome . ARTHRITIS RHEUM vol. 58 , ( 1 ) 273 - 283 .