Publications: Dr Muy-Teck Teh

Usman S, Waseem A, Teh MT, Tummala H, Ghaloum F, Yeudall WA ( 2024 ) . A single cysteine residue in vimentin regulates long non-coding RNA XIST to suppress epithelial-mesenchymal transition and stemness in breast cancer . eLife vol. 623301 ,

Pham T, Teh M-T, Chatzopoulou D, Holmes S, Coulthard P ( 2024 ) . Artificial Intelligence in Head and Neck Cancer: Innovations, Applications, and Future Directions . Current Oncology vol. 31 , ( 9 ) 5255 - 5290 .

Jamal A, Usman S, Teh M-T, Waseem A ( 2024 ) . Preparation and Use of shRNA for Knocking Down Specific Genes . Methods in Molecular Biology vol. 2849 , 55 - 72 .

Usman S, Bushaala A, Teh MT, Waseem A ( 2024 ) . Site-Directed Mutagenesis to Mutate Multiple Residues in a Single Reaction . Methods in Molecular Biology vol. 2849 , 123 - 133 .

Wan H, Teh M-T, Mastroianni G, Ahmad US ( 2023 ) . Comparative Transcriptome Analysis Identifies Desmoglein-3 as a Potential Oncogene in Oral Cancer Cells . Cells vol. 12 , ( 23 )

Teh M-T ( 2023 ) . Identification of multidrug chemoresistant genes in head and neck squamous cell carcinoma cells . Molecular Cancer

Perussolo J, Teh M-T, Gkranias N, Tiberi S, Petrie A, Cutino-Moguel M-T, Donos N ( 2023 ) . Efficacy of three antimicrobial mouthwashes in reducing SARS-CoV-2 viral load in the saliva of hospitalized patients: a randomized controlled pilot study . Scientific Reports vol. 13 , ( 1 )

Teh M-T ( 2023 ) . Methods for diagnosing cancer (Version 2 - USA) . no. 17628951 ,

Waseem A ( 2022 ) . Transcriptome Analysis Reveals Vimentin-Induced Disruption of Cell–Cell Associations Augments Breast Cancer Cell Migration . Cells

Usman S, Teh MT, Waseem A ( 2022 ) . Vimentin Mediated Downregulation of Intercelluar Associations Augments Cancer Cell Migration . https://www.per-iadr2020.com/docs/Abstract_Book.pdf . Conference: PER-IADR Oral Health Congress 2022 from: 17/09/2022 to: 15/09/2022 , 160 - 160 .

Usman S, Aldehlawi H, Nguyen TKN, Teh M-T, Waseem A ( 2022 ) . Impact of N-Terminal Tags on De Novo Vimentin Intermediate Filament Assembly . International Journal of Molecular Sciences vol. 23 , ( 11 ) 6349 - 6349 .

Teh M-T ( 2022 ) . Molecular Signatures of Tumour and Its Microenvironment for Precise Quantitative Diagnosis of Oral Squamous Cell Carcinoma: An International Multi-Cohort Diagnostic Validation Study . Cancers

Mech AM, Merteroglu M, Sealy IM, Teh M-T, White RJ, Havelange W, Brennan CH, Busch-Nentwich EM ( 2022 ) . Behavioral and Gene Regulatory Responses to Developmental Drug Exposures in Zebrafish . Frontiers in Psychiatry vol. 12 ,

Usman S, Teh MT, Waseem A ( 2021 ) . Free Head Domain of Vimentin Is Crucial For Filament Assembly . Conference: Cell Bio Virtual 2021 EMBO Meeting American Society of Cell Biology from: 10/12/2021 to: 01/12/2021 ,

Sapkota D, Sharma S, Søland TM, Braz‐Silva PH, Teh M ( 2021 ) . Expression profile of SARS‐CoV‐2 cellular entry proteins in normal oral mucosa and oral squamous cell carcinoma . Clinical and Experimental Dental Research

Usman S ( 2021 ) . Vimentin Is at the Heart of Epithelial Mesenchymal Transition (EMT) Mediated Metastasis . Cancers vol. 13 , ( 19 ) 4985 - 4985 .

Ponzoni L, Melzi G, Marabini L, Martini A, Petrillo G, Teh M-T, Torres-Perez JV, Morara S et al. ( 2021 ) . Conservation of mechanisms regulating emotional-like responses on spontaneous nicotine withdrawal in zebrafish and mammals . Progress in Neuro-Psychopharmacology and Biological Psychiatry vol. 111 ,

Teh M-T ( 2021 ) . Methods for diagnosing cancer (Version 2) . no. 1910444.7 ,

Usman S, Jamal A, Teh M-T, Waseem A ( 2021 ) . Major Molecular Signaling Pathways in Oral Cancer Associated With Therapeutic Resistance . Frontiers in Oral Health vol. 1 , 603160 - 603160 .

Ponzoni L, Teh MT, Torres-Perez JV, Brennan CH, Braida D, Sala M ( 2020 ) . Increased Response to 3,4-Methylenedioxymethamphetamine (MDMA) Reward and Altered Gene Expression in Zebrafish During Short- and Long-Term Nicotine Withdrawal . Molecular Neurobiology

Teh M-T ( 2020 ) . RASSF1A inhibits PDGFB-driven malignant phenotypes of nasopharyngeal carcinoma cells in a YAP1-dependent manner . Cell Death and Disease

Garcia Gonzalez J, Brock A, Parker M, Riley R, Joliffe D, SUDWARTS A, Teh M-T, Busch-Nentwich E et al. ( 2020 ) . Identification of Slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour . eLife

Aldehlawi H, Usman S, Lalli A, Ahmad F, WILLIAMS G, Teh M-T, Waseem A ( 2020 ) . Serum lipids, retinoic acid and phenol red differentially regulate expression of keratins K1, K10 and K2 in cultured keratinocytes . Scientific Reports vol. 10 , ( 4829 )

Teh M-T ( 2020 ) . A Novel Diagnostic Tool for Cancer Detection . Scientia

Uttagomol J, Ahmad US, Rehman A, Huang Y, Laly AC, Kang A, Soetaert J, Chance R et al. ( 2019 ) . Evidence for the Desmosomal Cadherin Desmoglein-3 in Regulating YAP and Phospho-YAP in Keratinocyte Responses to Mechanical Forces . International Journal of Molecular Sciences vol. 20 , ( 24 )

Teh M-T ( 2019 ) . The transcription factor FOXM1 regulates the balance between proliferation and aberrant differentiation in head and neck squamous cell carcinoma . Journal of Pathology

Yeung J-YS, Hutchison I, Waseem A, Teh M-T ( 2019 ) . qMIDS: A Digital Diagnostic Test for Oral Cancer . British Journal of Oral and Maxillofacial Surgery vol. 57 , ( 10 ) e86 - e87 .

Rehman A, Cai Y, Hünefeld C, Jedličková H, Huang Y, Teck Teh M, Sharif Ahmad U, Uttagomol J et al. ( 2019 ) . The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53 . Cell Death & Disease vol. 10 , ( 10 )

Teh M-T ( 2019 ) . Clinical correlation of opposing molecular signatures in head and neck squamous cell carcinoma . BMC Cancer

ALDEHLAWI H, Niemiec NA, AVISETTI DR, LALLI A, Teh M-T, WASEEM A ( 2019 ) . The monoclonal antibody EPR1614Y against the stem cell biomarker keratin K15 lacks specificity and reacts with other keratins . Scientific Reports vol. 9 , Article 1943 ,

TEH M ( 2018 ) . Transcriptome reprogramming by cancer exosomes: identification of novel molecular targets in matrix and immune modulation . Molecular Cancer

Pantazi E, Gemenetzidis E, Teh M-T, Reddy SV, Warnes G, Evagora C, Trigiante G, Philpott MP ( 2017 ) . GLI2 Is a Regulator of β-Catenin and Is Associated with Loss of E-Cadherin, Cell Invasiveness, and Long-Term Epidermal Regeneration . Journal of Investigative Dermatology vol. 137 , ( 8 ) 1719 - 1730 .

Parajuli H, Teh MT, Abrahamsen S, Christoffersen I, Neppelberg E, Lybak S, Osman T, Johannessen AC et al. ( 2016 ) . Integrin α11 is overexpressed by tumour stroma of head and neck squamous cell carcinoma and correlates positively with alpha smooth muscle actin expression . J Oral Pathol Med

TEH M, Wan HONG ( 2016 ) . Independent Evaluation of a FOXM1-based Quantitative Malignancy Diagnostic System (qMIDS) on Head and Neck Squamous Cell Carcinomas . Oncotarget vol. 7 , ( 34 ) 54555 - 54563 .

TEH M ( 2016 ) . Oral Cancer Biomarkers: Is it a Meaningless Game? . Dentistry Open Journal vol. 3 , ( 1 ) Article 1 , e1 - e3 .

Sapkota D, Bruland O, Parajuli H, Osman T, Teh MT, Johannessen A, Costea D ( 2016 ) . S100A16 Functions as a Tumor Suppressor Protein in Oral Squamous Cell Carcinoma . International Journal of Radiation Oncology • Biology • Physics . vol. 94 , 944 - 945 .

Parker MO, Brock AJ, Sudwarts A, Teh M-T, Combe FJ, Brennan CH ( 2015 ) . Developmental role of acetylcholinesterase in impulse control in zebrafish . Frontiers in Behavioral Neuroscience vol. 9 ,

Sapkota D, Bruland O, Parajuli H, Osman TA, Teh M-T, Johannessen AC, Costea DE ( 2015 ) . S100A16 promotes differentiation and contributes to a less aggressive tumor phenotype in oral squamous cell carcinoma . BMC Cancer vol. 15 , ( 1 )

TEH M ( 2015 ) . Is Salivary Exosome the Answer to Early Detection of Oral Cancer? . Dentistry Open Journal vol. 2 , ( 2 ) e3 - e4 .

Teh M-T ( 2015 ) . Can Challenges of Oral Cancer Diagnosis be Resolved? . Dental Health Current Research vol. 01 , ( 01 )

Nguyen NT, Mackenzie I, Teh M, Waseem A ( 2015 ) . HOXA7 suppresses keratinocyte differentiation via PKC/AP-1 pathway . MOLECULAR BIOLOGY OF THE CELL . vol. 26 ,

Parker MO, Annan LV, Kanellopoulos AH, Brock AJ, Combe FJ, Baiamonte M, Teh MT, Brennan CH ( 2014 ) . The utility of zebrafish to study the mechanisms by which ethanol affects social behavior and anxiety during early brain development . Progress in Neuro-Psychopharmacology and Biological Psychiatry vol. 55 , 94 - 100 .

Parker MO, Evans AM-D, Brock AJ, Combe FJ, Teh M-T, Brennan CH ( 2014 ) . Moderate alcohol exposure during early brain development increases stimulus‐response habits in adulthood . Addiction Biology vol. 21 , ( 1 ) 49 - 60 .

Schmidt BL, Kuczynski J, Bhattacharya A, Huey B, Corby PM, Queiroz ELS, Nightingale K, Kerr AR et al. ( 2014 ) . Changes in Abundance of Oral Microbiota Associated with Oral Cancer . PLOS ONE vol. 9 , ( 6 )

Parker MO, Annan LV, Kanellopoulos AH, Brock AJ, Combe FJ, Baiamonte M, Teh M-T, Brennan CH ( 2014 ) . The utility of zebrafish to study the mechanisms by which ethanol affects social behavior and anxiety during early brain development . Progress in Neuro-Psychopharmacology and Biological Psychiatry vol. 55 , 94 - 100 .

Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T et al. ( 2014 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . Cell Death & Disease . vol. 5 , e1028 - e1028 .

Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T et al. ( 2014 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . Cell Death Dis vol. 5 , ( 1 )

Hwang S, Mahadevan S, Qadir F, Hutchison IL, Costea DE, Neppelberg E, Liavaag PG, Waseem A et al. ( 2013 ) . Identification of FOXM1-induced epigenetic markers for head and neck squamous cell carcinomas . Cancer vol. 119 , ( 24 ) 4249 - 4258 .

Bose A, Teh M-T, Mackenzie IC, Waseem A ( 2013 ) . Keratin K15 as a Biomarker of Epidermal Stem Cells . International Journal of Molecular Sciences vol. 14 , ( 10 ) 19385 - 19398 .

Teh M-T, Hutchison IL, Costea DE, Neppelberg E, Liavaag PG, Purdie K, Harwood C, Wan H et al. ( 2013 ) . Exploiting FOXM1-orchestrated molecular network for early squamous cell carcinoma diagnosis and prognosis . Int J Cancer vol. 132 , ( 9 ) 2095 - 2106 .

Teh M-T ( 2012 ) . Cells brainwashed by FOXM1: do they have potential as biomarkers of cancer? . Biomark Med vol. 6 , ( 4 ) 499 - 501 .

Pitiyage GN, Lim KP, Gemenitzidis E, Teh M, Waseem A, Prime SS, Tilakaratne WM, Fortune F et al. ( 2012 ) . Increased secretion of tissue inhibitors of metalloproteinases 1 and 2 (TIMPs ‐1 and ‐2) in fibroblasts are early indictors of oral sub‐mucous fibrosis and ageing . Journal of Oral Pathology and Medicine vol. 41 , ( 6 ) 454 - 462 .

Teh MT ( 2012 ) . Methods for Diagnosing Cancer (Version 1) . no. PCT/GB2011/001130 ,

Teh M-T ( 2012 ) . FOXM1 coming of age: time for translation into clinical benefits? . Front Oncol vol. 2 ,

Teh M-T, Gemenetzidis E, Patel D, Tariq R, Nadir A, Bahta AW, Waseem A, Hutchison IL ( 2012 ) . FOXM1 induces a global methylation signature that mimics the cancer epigenome in head and neck squamous cell carcinoma . PLoS One vol. 7 , ( 3 )

Bose A, Teh M-T, Hutchison IL, Wan H, Leigh IM, Waseem A ( 2012 ) . Two mechanisms regulate keratin K15 expression in keratinocytes: role of PKC/AP-1 and FOXM1 mediated signalling . PLoS One vol. 7 , ( 6 )

TEH M ( 2011 ) . Chapter 14: Initiation of Human Tumourigenesis: Upregulation of FOXM1 Transcription Factor . Stem Cells and Cancer Stem Cells,Volume 3 , Editors: Hayat, MA , Springer Verlag

Teh M-T ( 2011 ) . Initiation of Human Tumourigenesis: Upregulation of FOXM1 Transcription Factor . Stem Cells and Cancer Stem Cells,Volume 3 , Springer Nature

( 2011 ) . Correction: Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1 . Cancer Research vol. 71 , ( 1 ) 290 - 290 .

Teh M-T, Parkinson EK, Thurlow JK, Liu F, Fortune F, Wan H ( 2011 ) . A molecular study of desmosomes identifies a desmoglein isoform switch in head and neck squamous cell carcinoma . J Oral Pathol Med vol. 40 , ( 1 ) 67 - 76 .

Gemenetzidis E, Costea DE, Parkinson EK, Waseem A, Wan H, Teh MT ( 2010 ) . Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1 . Cancer Research vol. 22 , ( 70 ) 9515 - 9526 .

Waseem A, Ali M, Odell EW, Fortune F, Teh M-T ( 2010 ) . Downstream targets of FOXM1: CEP55 and HELLS are cancer progression markers of head and neck squamous cell carcinoma . Oral Oncol vol. 46 , ( 7 ) 536 - 542 .

Wang HX, Teh MT, Ji YM, Patel V, Firouzabadian S, Patel AA, Gutkind JS, Yeudall WA ( 2010 ) . EPS8 upregulates FOXM1 expression, enhancing cell growth and motility . CARCINOGENESIS vol. 31 , ( 6 ) 1132 - 1141 .

Tsang S, Liu L, Teh M, Wheeler A, Piper K, Grose R, Hart I, Garrod D et al. ( 2010 ) . Novel role for human desmoglein 3 in regulating E-cadherin mediated adherens junctions through Src family kinase activation . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 130 , S33 - S33 .

Pantazi E, Trigiante G, Warnes G, Gemenetzidis E, Teh MT, Ikram M, Shan L, Lu YJ et al. ( 2010 ) . Overexpression of GLI2 in human keratinocytes results in resistance to ultraviolet B-induced apoptosis and increased chromosomal instability . BRITISH JOURNAL OF DERMATOLOGY . vol. 162 , 948 - 948 .

Teh M-T, Gemenetzidis E, Chaplin T, Young BD, Philpott MP ( 2010 ) . Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes . Mol Cancer vol. 9 ,

Tsang SM, Liu L, Teh M-T, Wheeler A, Grose R, Hart IR, Garrod DR, Fortune F et al. ( 2010 ) . Desmoglein 3, via an interaction with E-cadherin, is associated with activation of Src . PloS ONE vol. 5 , ( 12 )

Gemenetzidis E, Elena-Costea D, Parkinson EK, Waseem A, Wan H, Teh MT ( 2010 ) . Induction of Human Epithelial Stem/Progenitor Expansion by FOXM1 . Cancer Research vol. 70 , ( 22 ) Article N/A , 9515 - 9526 .

Pantazi E, Trigianti G, Warnes G, Gemenetzidis E, Teh MT, Philpott MP ( 2009 ) . Overexpression of GLI2 in human keratinocytes results in polyploidy and resistance to ultraviolet B-induced apoptosis . BRITISH JOURNAL OF DERMATOLOGY . vol. 160 , 908 - 908 .

Gemenetzidis E, Bose A, Riaz AM, Chaplin T, Young BD, Ali M, Sugden D, Thurlow JK et al. ( 2009 ) . FOXM1 upregulation is an early event in human squamous cell carcinoma and it is enhanced by nicotine during malignant transformation . PLoS One vol. 4 , ( 3 )

Teh MT, Tilakaratne WM, Chaplin T, Young BD, Ariyawardana A, Pitiyage G, Lalli A, Stewart JE et al. ( 2008 ) . Fingerprinting genomic instability in oral submucous fibrosis . J Oral Pathol Med vol. 37 , ( 7 ) 430 - 436 .

Tilakaratne WM, Iqbal Z, Teh MT, Ariyawardana A, Pitiyage G, Cruchley A, Stewart JE, Hagi-Pavli E et al. ( 2008 ) . Upregulation of HIF-1 alpha in malignant transformation of oral submucous fibrosis . J ORAL PATHOL MED vol. 37 , ( 6 ) 372 - 377 .

Lalli A, Tilakaratne WM, Ariyawardana A, Fitchett C, Leigh IM, Hagi-Pavli E, Cruchley AT, Parkinson EK et al. ( 2008 ) . An altered keratinocyte phenotype in oral submucous fibrosis: correlation of keratin K17 expression with disease severity . J ORAL PATHOL MED vol. 37 , ( 4 ) 211 - 220 .

Faust R, Garratt PJ, Perez MAT, Piccio VJD, Madsen C, Stenstrom A, Frolund B, Davidson K et al. ( 2007 ) . 7-Substituted-melatonin and 7-substituted-1-methylmelatonin analogues: Effect of substituents on potency and binding affinity . BIOORGAN MED CHEM vol. 15 , ( 13 ) 4543 - 4551 .

Purdie KJ, Lambert SR, Teh M-T, Chaplin T, Molloy G, Raghavan M, Kelsell DP, Leigh IM et al. ( 2007 ) . Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis . Genes Chromosomes Cancer vol. 46 , ( 7 ) 661 - 669 .

Purdie K, Lambert S, Teh M, Chaplin T, Molloy G, Raghavan M, Kelsell DP, Leigh IM et al. ( 2007 ) . Allelic imbalances and microdeletions affecting the PTPRD gene in cutaneous squamous cell carcinomas detected using single nucleotide polymorphism microarray analysis . BRITISH JOURNAL OF DERMATOLOGY . vol. 156 , 1100 - 1101 .

Tilakaratne W, Iqbal Z, Teh MT, Ariyawardana A, Pitiyage G, Cruchley A, Hagi-Pavli E, Lalli A et al. ( 2007 ) . P245 Up regulation of HIF-1a in the progression and malignant transformation of oral submucous fibrosis . Oral Oncology Supplement vol. 2 , ( 1 ) 204 - 205 .

Tilakaratne W, Iqball Z, Teh MT, Ariyawardana A, Pitiyage G, Cruchley A, Hagi-Pavli E, Lalli A et al. ( 2007 ) . Up regulation of HIF-1 alpha in the progression and malignant transformation of oral submucous fibrosis . ORAL ONCOLOGY . vol. 2 , 204 - 205 .

Teh MT, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM et al. ( 2007 ) . Erratum: Role for WNT16B in human epidermal keratinocyte proliferation and differentiation (Journal of Cell Science vol. 120 (330-339)) . Journal of Cell Science vol. 120 , ( 5 )

Teh MT, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM et al. ( 2007 ) . Role for WNT16B in human epidermal keratinocyte proliferation and differentiation (vol 120, pg 330, 2007) . J CELL SCI vol. 120 , ( 5 ) 917 - 917 .

Teh M-T, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM et al. ( 2007 ) . Role for WNT16B in human epidermal keratinocyte proliferation and differentiation . J Cell Sci vol. 120 , ( Pt 2 ) 330 - 339 .

Blaydon DC, Ishii Y, O'Toole EA, Unsworth HC, Teh M-T, Rüschendorf F, Sinclair C, Hopsu-Havu VK et al. ( 2006 ) . The gene encoding R-spondin 4 (RSPO4), a secreted protein implicated in Wnt signaling, is mutated in inherited anonychia . Nat Genet vol. 38 , ( 11 ) 1245 - 1247 .

Blaydon DC, Ishii Y, O'Toole EA, Teh MT, Hopsu-Havu VK, Moss C, Ruschendorf F, Wajid M et al. ( 2006 ) . R-spondin 4 (RSPO4), a novel secreted protein implicated in Wnt signalling, is mutated in inherited anonychia . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 126 , 31 - 31 .

Tsotinis A, Vlachou M, Papahatjis DP, Calogeropoulou T, Nikas SP, Garratt PJ, Piccio V, Vonhoff S et al. ( 2006 ) . Mapping the melatonin receptor. 7. Subtype selective ligands based on beta-substituted N-acyl-5-methoxytryptamines and beta-substituted N-acyl-5-methoxy-1-methyltryptamines . J MED CHEM vol. 49 , ( 12 ) 3509 - 3519 .

Purdie K, Teh M, Harwood C, Young B, Proby C, Leigh I ( 2006 ) . Allelic imbalances and chromosome 9p microdeletion demonstrated in cutaneous squamous cell carcinomas using single nucleotide polymorphism microarray analysis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 126 , 18 - 18 .

Teh M-T, Blaydon D, Chaplin T, Foot NJ, Skoulakis S, Raghavan M, Harwood CA, Proby CM et al. ( 2005 ) . Genomewide single nucleotide polymorphism microarray mapping in basal cell carcinomas unveils uniparental disomy as a key somatic event . Cancer Res vol. 65 , ( 19 ) 8597 - 8603 .

Kelsell DP, Norgett EE, Unsworth H, Teh MT, Cullup T, Mein CA, Dopping-Hepenstal PJ, Kennedy CT et al. ( 2005 ) . Clinical and molecular features of Harlequin ichthyosis . BRITISH JOURNAL OF DERMATOLOGY . vol. 153 , 5 - 5 .

Kelsell DP, Norgett EE, Unsworth H, Teh M-T, Cullup T, Mein CA, Dopping-Hepenstal PJ, Dale BA et al. ( 2005 ) . Mutations in ABCA12 underlie the severe congenital skin disease harlequin ichthyosis . Am J Hum Genet vol. 76 , ( 5 ) 794 - 803 .

Teh M, Quinn AG, Philpott MP ( 2005 ) . FOXM1b activates DNA repair and suppresses UVB-induced apoptosis in human keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 124 , A17 - A17 .

Blaydon DC, Teh M, Foot NJ, Philpott MP, Harwood C, Proby C, Young BD, Kelsell DP ( 2005 ) . Genome-wide SNP microarray mapping in basal cell carcinomas unveils uniparental dismay as a key somatic event . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 124 , A20 - A20 .

Kelsell DP, Norgett E, Unsworth H, Teh M, Cullop T, Dale B, Leigh IM, Eady RA et al. ( 2005 ) . Mutations in ABCA12 underlie harlequin ichthyosis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 124 , A75 - A75 .

Teh MT, Quinn AG, Philpott MP ( 2005 ) . The Human forkhead transcription factor FOXM1B enhances DNA repair and suppresses UVB-induced apoptosis . BRITISH JOURNAL OF DERMATOLOGY . vol. 152 , 842 - 843 .

Sugden D, Davidson K, Hough KA, Teh M-T ( 2004 ) . Melatonin, melatonin receptors and melanophores: a moving story . Pigment Cell Res vol. 17 , ( 5 ) 454 - 460 .

Davies DJ, Faust R, Garratt PJ, Marivingt-Mounir C, Davidson K, Teh MT, Sugden D ( 2004 ) . Binding affinity and biological activity of oxygen and sulfur isosteres at melatonin receptors as a function of their hydrogen bonding capability . BIOORG CHEM vol. 32 , ( 1 ) 1 - 12 .

Teh M-T, Wong S-T, Neill GW, Ghali LR, Philpott MP, Quinn AG ( 2002 ) . FOXM1 is a downstream target of Gli1 in basal cell carcinomas . Cancer Res vol. 62 , ( 16 ) 4773 - 4780 .

Philpott MP, NEILL GW, Leigh IM, Quinn AG, Ghali LR, Wong ST, Teh MT ( 2002 ) . FOXM1 is a downstream target of Gli1 in basal cell carcinomas . Cancer Res. vol. 62 , ( 16 ) 4773 - 4780 .

Teh M-T, Sugden D ( 2002 ) . Desensitization of pigment granule aggregation in Xenopus leavis melanophores: melatonin degradation rather than receptor down-regulation is responsible . J Neurochem vol. 81 , ( 4 ) 719 - 727 .

Teh MT, Wong ST, Neill G, Ghali L, Philpott M, Quinn A ( 2002 ) . FOXM1 is a downstream target of hedgehog signalling in basal cell carcinomas (BCC) . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 119 , 742 - 742 .

Teh MT, Sugden D ( 2001 ) . An endogenous 5-HT7 receptor mediates pigment granule dispersion in Xenopus laevis melanophores . BRIT J PHARMACOL vol. 132 , ( 8 ) 1799 - 1808 .

Teh MT ( 2000 ) . Cellular and Molecular Studies on Pigment-Granule Translocation in Xenopus Melanophores . Supervisors: Sugden, DD , Presented at: King's College, University of London ,

Faust R, Garratt PJ, Jones R, Yeh LK, Tsotinis A, Panoussopoulou M, Calogeropoulou T, Teh MT et al. ( 2000 ) . Mapping the melatonin receptor. 6. Melatonin agonists and antagonists derived from 6H-isoindolo[2,1-a]indoles, 5,6-dihydroindolo[2,1-a]isoquinolines, and 6,7-dihydro-5H-benzo[c]azepino[2,1-a]indoles . J MED CHEM vol. 43 , ( 6 ) 1050 - 1061 .

Li PK, Sugden D, Teh MT, Chu GH, Witt-Enderby PA ( 1999 ) . Synthesis and studies of irreversible melatonin receptor ligands . ABSTR PAP AM CHEM S vol. 218 , U962 - U962 .

Sugden D, Yeh LK, Teh MT ( 1999 ) . Design of subtype selective melatonin receptor agonists and antagonists . REPRODUCTION NUTRITION DEVELOPMENT . vol. 39 , 335 - 344 .

Teh MT, Sugden D ( 1999 ) . The putative melatonin receptor antagonist GR128107 is a partial agonist on Xenopus laevis melanophores . BRIT J PHARMACOL vol. 126 , ( 5 ) 1237 - 1245 .

Teh MT, Sugden D ( 1998 ) . GR128107 is a partial melatonin receptor agonist on Xenopus laevis melanophores . BRIT J PHARMACOL vol. 125 , U39 - U39 .

Teh MT, Sugden D ( 1998 ) . Comparison of the structure-activity relationships of melatonin receptor agonists and antagonists: Lengthening the N-acyl side-chain has differing effects on potency on Xenopus melanophores . N-S ARCH PHARMACOL vol. 358 , ( 5 ) 522 - 528 .

Davies DJ, Garratt PJ, Tocher DA, Vonhoff S, Davies J, Teh MT, Sugden D ( 1998 ) . Mapping the melatonin receptor. 5. Melatonin agonists and antagonists derived from tetrahydrocyclopent[b]indoles, tetrahydrocarbazoles and hexahydrocyclohept[b]indoles . J MED CHEM vol. 41 , ( 4 ) 451 - 467 .

Sugden D, Pickering H, Teh MT, Garratt PJ ( 1997 ) . Melatonin receptor pharmacology: toward subtype specificity . BIOLOGY OF THE CELL . vol. 89 , 531 - 537 .