Publications: Prof Julia Shelton
Diaz-Lopez RA, Wen PH, Shelton JC
(
2023
)
.
Influence of Taper surface topographies on contact deformation and stresses
.
Journal of the Mechanical Behavior of Biomedical Materials
vol.
148
,
Diaz-Lopez RA, Wen PH, Shelton JC
(
2022
)
.
Influence of taper design and loading on taper micromotion
.
Journal of the Mechanical Behavior of Biomedical Materials
vol.
128
,
Wu H, Wang Z, Liu S, Meng H, Liu S, Shelton JC, Thompson CL, Fu S et al.
(
2021
)
.
Sub-toxic levels of cobalt ions impair mechanostranduction via HDAC6-depedent primary cilia shortening
.
Biochem Biophys Res Commun
Xu J, Yang J, Chen J, Zhang X, Wu Y, Hart A, Nyga A, Shelton JC
(
2020
)
.
Activation of synovial fibroblasts from patients at revision of their metal-on-metal total hip arthroplasty
.
Particle and Fibre Toxicology
vol.
17
,
(
1
)
42
-
42
.
Di Federico E, Bader DL, Shelton JC
(
2020
)
.
3D models of chondrocytes within biomimetic scaffolds: Effects of cell deformation from loading regimens
.
Clinical Biomechanics
Fu S, Meng H, Freer F, Kwon J, Shelton JC, Knight MM
(
2019
)
.
Sub-toxic levels of Co2+ are anti-inflammatory and protect cartilage from degradation caused by IL-1β
.
Clinical Biomechanics
vol.
79
,
VADGAMA PM
(
2019
)
.
An electrochemical study of acrylate bone adhesive permeability and selectivity change during in vitro ageing: a model approach to the study of biomaterials and membrane barriers
.
Analytica Chimica Acta
Rowson DT, Shelton JC, Screen HRC, Knight MM
(
2018
)
.
Mechanical loading induces primary cilia disassembly in tendon cells via TGFβ and HDAC6
.
Scientific Reports
vol.
8
,
(
1
)
Xu J, Nyga A, Li W, Zhang X, Gavara N, Knight MM, Shelton JC
(
2018
)
.
Cobalt ions stimulate a fibrotic response through matrix remodelling, fibroblast contraction and release of pro-fibrotic signals from macrophages
.
European Cells and Materials
vol.
36
,
142
-
155
.
SHELTON JC
(
2018
)
.
Prediction of taper performance using quasi static FE models: The influence of loading and taper clearance and trunnion length
.
Journal of Biomedical Materials Research: Part B - Applied Biomaterials
Xu J, Yang J, Nyga A, Ehteramyan M, Moraga A, Wu Y, Zeng L, Knight MM et al.
(
2018
)
.
Cobalt (II) ions and nanoparticles induce macrophage retention by ROS-mediated down-regulation of RhoA expression
.
Acta Biomater
vol.
72
,
434
-
446
.
SHELTON JC
(
2018
)
.
Cobalt (II) ions and nanoparticles induce macrophage retention by ROS-mediated downregulation of RhoA expression
.
Acta Biomaterialia
vol.
72
,
434
-
446
.
Clarke I, Shelton J, Bowsher J, Savisaar C, Donaldson T
(
2017
)
.
Simulator Study of MOM using Steep-cup Flexion - A Clinically Relevant Incorporation of Intermittent Edge-loading
.
Reconstructive Review
vol.
7
,
(
3
)
Di Federico E, SHELTON JC, Bader DL
(
2017
)
.
Complex mechanical conditioning of cell-seeded agarose constructs can influence chondrocyte biosynthetic activity
.
Biotechnology and Bioengineering
de Villiers D, Shelton JC
(
2016
)
.
Measurement outcomes from hip simulators
.
Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine
vol.
230
,
(
5
)
398
-
405
.
de Villiers D, Traynor A, Collins SN, Shelton JC
(
2015
)
.
The increase in cobalt release in metal-on-polyethylene hip bearings in tests with third body abrasives
.
Proceedings of the Institution of Mechanical Engineers Part H Journal of Engineering in Medicine
vol.
229
,
(
9
)
611
-
618
.
de Villiers D, Traynor A, Collins SN, Banfield S, Housden J, Shelton JC
(
2015
)
.
Chromium nitride coating for large diameter metal-on-polyethylene hip bearings under extreme adverse hip simulator conditions
.
Wear
vol.
328
,
363
-
368
.
Di Federico E, Bader DL, Shelton JC
(
2014
)
.
Design and validation of an in vitro loading system for the combined application of cyclic compression and shear to 3D chondrocytes-seeded agarose constructs
.
Med Eng Phys
vol.
36
,
(
4
)
534
-
540
.
Hothi HS, Busfield JJC, Shelton JC
(
2014
)
.
Deformation of uncemented metal acetabular cups following impaction: Experimental and finite element study
.
Computer Methods in Biomechanics and Biomedical Engineering
vol.
17
,
(
11
)
1261
-
1274
.
Screen HRC, Toorani S, Shelton JC
(
2013
)
.
Microstructural stress relaxation mechanics in functionally different tendons
.
Medical Engineering and Physics
vol.
35
,
(
1
)
96
-
102
.
Screen HRC, Toorani S, Shelton JC
(
2013
)
.
Microstructural stress relaxation mechanics in functionally different tendons
.
Med Eng Phys
vol.
35
,
(
1
)
96
-
102
.
Lu F, Royle M, Lali FV, Hart AJ, Collins S, Housden J, Shelton JC
(
2012
)
.
Simple isolation method for the bulk isolation of wear particles from metal on metal bearing surfaces generated in a hip simulator test
.
Journal of Materials Science: Materials in Medicine
vol.
23
,
(
4
)
891
-
901
.
Lu F, Royle M, Lali FV, Hart AJ, Collins S, Housden J, Shelton JC
(
2012
)
.
Simple isolation method for the bulk isolation of wear particles from metal on metal bearing surfaces generated in a hip simulator test
.
Journal of Materials Science: Materials in Medicine1
-
11
.
Morris B, Zou L, Royle M, Simpson D, Shelton JC
(
2011
)
.
Quantifying the wear of acetabular cups using coordinate metrology
.
Wear
vol.
271
,
(
7-8
)
1086
-
1092
.
Hothi HS, Busfield JJC, Shelton JC
(
2011
)
.
Explicit finite element modelling of the impaction of metal press-fit acetabular components
.
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
vol.
225
,
(
3
)
303
-
314
.
McConlogue T, Mueller J, Shelton J
(
2010
)
.
Challenges of developing engineering students' writing through peer assessment
.
Engineering Education 2010: Inspiring the Next Generation of Engineers, EE 2010
Maeda E, Fleischmann C, Mein CA, Shelton JC, Bader DL, Lee DA
(
2010
)
.
Functional analysis of tenocytes gene expression in tendon fascicles subjected to cyclic tensile strain
.
Connective Tissue Research
vol.
51
,
(
6
)
434
-
444
.
Maeda E, Shelton JC, Bader DL, Lee DA
(
2009
)
.
Effect of intermittent cyclic tensile strain on collagen synthesis by tenocytes in isolated fascicles
.
Journal of Biomechanical Science and Engineering
vol.
4
,
(
4
)
510
-
517
.
Angadji A, Royle M, Collins SN, Shelton JC
(
2009
)
.
Influence of cup orientation on the wear performance of metal-on-metal hip replacements
.
Proceedings of the Institution of Mechanical Engineers, Part H: Journal of Engineering in Medicine
vol.
223
,
(
4
)
449
-
457
.
Maeda E, Shelton JC, Bader DL, Lee DA
(
2009
)
.
Differential regulation of gene expression in isolated tendon fascicles exposed to cyclic tensile strain in vitro
.
Journal of Applied Physiology
vol.
106
,
(
2
)
506
-
512
.
Berry CC, Shelton JC, Lee DA
(
2009
)
.
Cell-generated forces influence the viability, metabolism and mechanical properties of fibroblast-seeded collagen gel constructs
.
J Tissue Eng Regen Med
vol.
3
,
(
1
)
43
-
53
.
Angadji A, Grossmann H, Royle M, Collins SN, Shelton JC
(
2008
)
.
Affect of cup positioning on the wear performance and wear particles from metal-on-metal hip replacements
.
8th World Biomaterials Congress 2008
vol.
2
,
Toorani S, Shelton JC, Screen HRC
(
2008
)
.
Characterizing structure-function relationships in tendon
.
8th World Biomaterials Congress 2008
vol.
2
,
Maeda E, Shelton JC, Bader DL, Lee DA
(
2008
)
.
Collagen synthesis by tenocytes in fascicles subjected to intermittent cyclic strain
.
European Cells and Materials
vol.
16
,
(
SUPPL. 3
)
Schulz RM, Wüstneck N, Van Donkelaar CC, Shelton JC, Bader A
(
2008
)
.
Development and validation of a novel bioreactor system for load- and perfusion-controlled tissue engineering of chondrocyte-constructs
.
Biotechnology and Bioengineering
vol.
101
,
(
4
)
714
-
728
.
Mootanah R, Jarrett P, Ingle P, Cheah K, Dowell JK, Shelton JC
(
2008
)
.
Configuration of anchorage holes affects cemented fixation of the acetabular component in total hip replacement: an in vitro study
.
Technol Health Care
vol.
16
,
(
1
)
19
-
30
.
Mootanah R, Dowell JK, Cheah K, Ingle P, Shelton JC
(
2007
)
.
Configuration of anchorage holes affects fixation of the acetabular component in cemented total hip replacement--a finite element study
.
Comput Methods Biomech Biomed Engin
vol.
10
,
(
6
)
439
-
445
.
Maeda E, Shelton JC, Bader DL, Lee DA
(
2007
)
.
Time dependence of cyclic tensile strain on collagen production in tendon fascicles
.
Biochem Biophys Res Commun
vol.
362
,
(
2
)
399
-
404
.
Maeda E, Shelton JC, Bader DL, Lee DA
(
2007
)
.
Gene expressions in tendon fascicles subjected to cyclic tensile strain
.
TISSUE ENGINEERING
.
vol.
13
,
1701
-
1701
.
Toorani S, Shelton JC, Screen HRC
(
2007
)
.
The relationship between tendon composition, structure, and mechanical characteristics
.
TISSUE ENGINEERING
.
vol.
13
,
1765
-
1765
.
Screen HRC, Chhaya VH, Greenwald SE, Bader DL, Lee DA, Shelton JC
(
2006
)
.
The influence of swelling and matrix degradation on the microstructural integrity of tendon
.
Acta Biomater
vol.
2
,
(
5
)
505
-
513
.
Bowsher JG, Nevelos J, Williams PA, Shelton JC
(
2006
)
.
'Severe' wear challenge to 'as-cast' and 'double heat-treated' large-diameter metal-on-metal hip bearings
.
P I MECH ENG H
vol.
220
,
(
H2
)
135
-
143
.
Bowsher JG, Hussain A, Williams PA, Shelton JC
(
2006
)
.
Metal-on-metal hip simulator study of increased wear particle surface area due to 'severe' patient activity
.
Proc Inst Mech Eng H
vol.
220
,
(
2
)
279
-
287
.
Screen HRC, Bader DL, Shelton JC, Lee DA
(
2005
)
.
Cyclic mechanical conditioning of isolated tendon fascicles results in an upregulation of collagen production
.
Proceedings of the 2005 Summer Bioengineering Conference
vol.
2005
,
193
-
194
.
Screen HRC, Shelton JC, Bader DL, Lee DA
(
2005
)
.
Cyclic tensile strain upregulates collagen synthesis in isolated tendon fascicles
.
Biochem Biophys Res Commun
vol.
336
,
(
2
)
424
-
429
.
Screen HRC, Shelton JC, Chhaya VH, Kayser MV, Bader DL, Lee DA
(
2005
)
.
The influence of noncollagenous matrix components on the micromechanical environment of tendon fascicles
.
Ann Biomed Eng
vol.
33
,
(
8
)
1090
-
1099
.
Screen HRC, Shelton JC, Bader DL, Lee DA
(
2005
)
.
Cyclic tensile strain upregulates collagen production in isolated tendon fascicles
.
INTERNATIONAL JOURNAL OF EXPERIMENTAL PATHOLOGY
.
vol.
86
,
A8
-
A9
.
Mulholland JW, Shelton JC, Luo XY
(
2005
)
.
Blood flow and damage by the roller pumps during cardiopulmonary bypass
.
J FLUID STRUCT
vol.
20
,
(
1
)
129
-
140
.
Bowsher JG, Hussain A, Williams P, Nevelos J, Shelton JC
(
2004
)
.
Effect of ion implantation on the tribology of metal-on-metal hip prostheses
.
J Arthroplasty
vol.
19
,
(
8 Suppl 3
)
107
-
111
.
Bader DL, Shelton JC, Lee DA, SCREEN HRC
(
2004
)
.
Local Strain Measurement within Tendon
.
Strain
vol.
40
,
(
4
)
157
-
163
.
Sawae Y, Shelton JC, Bader DL, Knight MM
(
2004
)
.
Confocal analysis of local and cellular strains in chondrocyte-agarose constructs subjected to mechanical shear
.
Ann Biomed Eng
vol.
32
,
(
6
)
860
-
870
.
Silwood CJL, Chikanza IC, Tanner KE, Shelton JC, Bowsher JG, Grootveld M
(
2004
)
.
Investigation of the molecular nature of low-molecular-mass cobalt(II) ions in isolated osteoarthritic knee-joint synovial fluid
.
FREE RADICAL RES
vol.
38
,
(
6
)
561
-
571
.
Screen HRC, Lee DA, Bader DL, Shelton JC
(
2004
)
.
An investigation into the effects of the hierarchical structure of tendon fascicles on micromechanical properties
.
Proc Inst Mech Eng H
vol.
218
,
(
2
)
109
-
119
.
Fisher J, SHELTON JC, Nevelos J
(
2004
)
.
Metallurgical Considerations in the Wear of Metal-Metal Hip Bearings
.
Hip International
vol.
14
,
1
-
10
.
Mootanah R, Ingle P, Cheah K, Dowell JK, Shelton JC
(
2004
)
.
Total hip replacement: Results of a postal survey of current practice on the cement fixation of the acetubular cup in the UK
.
HIP International
vol.
14
,
(
3
)
155
-
162
.
Chowdhury TT, Bader DL, Shelton JC, Lee DA
(
2003
)
.
Temporal regulation of chondrocyte metabolism in agarose constructs subjected to dynamic compression
.
Arch Biochem Biophys
vol.
417
,
(
1
)
105
-
111
.
Berry CC, Shelton JC, Bader DL, Lee DA
(
2003
)
.
Influence of external uniaxial cyclic strain on oriented fibroblast-seeded collagen gels
.
Tissue Eng
vol.
9
,
(
4
)
613
-
624
.
Bader DL, SHELTON JC, Knight MM, Sawae Y
(
2003
)
.
Confocal Analysis of Local and Cellular Strains in Chondrocyte - Agarose Constructs Subjected to Shear
.
J Biochemical Engineering ASME
Chowdhury TT, Shelton JC, Bader DL, LEE DA
(
2003
)
.
Control of mechanotrasduction processes in dynamically stimulated human and bovine chondrocytes cultured in agarose constructs
.
Internat. J. Artificial Organs
vol.
26
,
(
9
)
858
-
858
.
Berry CC, Cacou C, Lee DA, Bader DL, Shelton JC
(
2003
)
.
Dermal fibroblasts respond to mechanical conditioning in a strain profile dependent manner
.
Biorheology
vol.
40
,
(
1-3
)
337
-
345
.
Screen HRC, Lee DA, Bader DL, Shelton JC
(
2003
)
.
Development of a technique to determine strains in tendons using the cell nuclei
.
Biorheology
vol.
40
,
(
1-3
)
361
-
368
.
Shelton JC, Bader DL, Lee DA
(
2003
)
.
Mechanical conditioning influences the metabolic response of cell-seeded constructs
.
Cells Tissues Organs
vol.
175
,
(
3
)
140
-
150
.
SCREEN HRC, Shelton JC, Bader DL, Lee DA
(
2003
)
.
The effects on non-collagenous matrix components on tendon fascicle micromechanics
.
Trans. Orthop. Res. Soc.
.
Conference:
49th Annual Meeting of the Orthopaedic Research Society
vol.
28
,
806
-
806
.
Chowdhury TT, LEE DA, Salter DM, Shelton JC, Bader DL
(
2003
)
.
alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta-stimulated human chondrocyte / agarose constructs and subjected to dynamic compression
.
Osteoarthritis Cartilage
vol.
11
,
(
Suppl 1
)
S2
-
S3
.
Chowdhury TT, LEE DA, Salter DM, Shelton JC, Bader DL
(
2003
)
.
alpha5beta1 integrin mediates mechanotransduction processes in TGFbeta3-stimulated human chondrocytes seeded in agarose constructs and subjected to dynamic compression
.
Tissue Engineering
.
Conference:
ETES
vol.
9
,
792
-
792
.
Kakunai S, Sakamoto T, Sakurai D, Aota Y, Shelton J
(
2002
)
.
Profile measurement of worn acetabular cup by holographic contouring
.
JSME INT J C-MECH SY
vol.
45
,
(
4
)
1028
-
1032
.
Berry CC, Shelton JC, Bader DL, Lee DA
(
2002
)
.
The influence of uniaxial cyclic strain on orientated fibroblast seeded collagen gels
.
Third Smith and Nephew International Symposium - Translating Tissue Engineering into Products
Mushipe MT, Revell PA, Shelton JC
(
2002
)
.
Cancellous bone repair using bovine trabecular bone matrix particulates
.
Biomaterials
vol.
23
,
(
2
)
365
-
370
.
Saadalla ME, Ahad N, Gibson IR, Shelton JC
(
2002
)
.
Comparison between commercial calcium phosphate bone cements
.
BIOCERAMICS 14
vol.
218-2
,
331
-
334
.
SHELTON JC, Revell PA, Mushipe MT
(
2002
)
.
Comparison of influence of cortical bone repair using autologous and Endobon particulates
.
J Mats Sci: Materials in Medicine
vol.
13
,
99
-
105
.
BADER DL, Shelton JC, Lee DA, Screen HRC
(
2002
)
.
Development of a technique to determine strains in tendons using the cell nuclei
.
Biorheology
vol.
40
,
361
-
368
.
SHELTON JC, Revell PA, Mushipe MT
(
2002
)
.
Enhancement of cancellous bone repair using particulates
.
Biomaterials
vol.
23
,
365
-
370
.
Bader DL, Shelton JC, Lee DA, SCREEN HRC
(
2002
)
.
Non-collagenous matrix components influence the micromechanical environment of tenocytes within tendon fascicles subjected to tensile strain
.
Eur. Cells Mat.
vol.
4:S1
,
41
-
42
.
Mushipe MT, Revell PA, Shelton JC
(
2002
)
.
The effects of bovine trabecular bone matrix particulates on cortical bone repair
.
J Mater Sci Mater Med
vol.
13
,
(
1
)
99
-
105
.
SCREEN HRC, Lee DA, Bader DL, Shelton JC
(
2002
)
.
The strain behaviour of tendon under tensile load, using cell nuclei as strain markers
.
Trans. Orthop. Res. Soc.
.
Conference:
48th Annual Meeting of the Orthopaedic Research Society
vol.
27
,
604
-
604
.
SHELTON JC, Bowsher JG
(
2001
)
.
A hip simulator study of the influence of patient activity level on the wear of crosslinked polyethylene under smooth and roughened femoral conditions
.
Wear
vol.
250
,
(
1-2
)
167
-
179
.
Bowsher JG, Shelton JC
(
2001
)
.
Hip simulator study of the influence of patient activity level on the wear of crosslinked polyethylene under smooth and roughened femoral conditions
.
WEAR
.
vol.
250
,
167
-
179
.
Ind TEJ, Shelton JC, Shepherd JH
(
2001
)
.
Influence of training on reliability of surgical knots
.
BRIT J OBSTET GYNAEC
vol.
108
,
(
10
)
1013
-
1016
.
Zou L, Samarawickrama DYD, Jovanovski V, Shelton JC
(
2001
)
.
Measurements of sequential impressions of acetabula cups from a total hip joint replacement using a non-contact measurement system
.
INTERNATIONAL JOURNAL OF MACHINE TOOLS & MANUFACTURE
vol.
41
,
(
13-14
)
2023
-
2030
.
Berry CC, Cacou C, Shelton JC, Bader DL, Lee DA
(
2000
)
.
Biological response of cyclic strain on developed cell seeded collagen gel model
.
Second Smith and Nephew International Symposium - Tissue Engineering 2000: Advances in Tissue Engineering, Biomaterials and Cell Signalling
Mulholland JW, Massey W, Shelton JC
(
2000
)
.
Investigation and quantification of the blood trauma caused by the combined dynamic forces experienced during cardiopulmonary bypass
.
Perfusion
vol.
15
,
(
6
)
485
-
494
.
Cacou C, Palmer D, Lee DA, Bader DL, Shelton JC
(
2000
)
.
A system for monitoring the response of uniaxial strain on cell seeded collagen gels
.
MED ENG PHYS
vol.
22
,
(
5
)
327
-
333
.
Mootanah R, Ingle P, Dowell J, Cheah K, Shelton JC
(
2000
)
.
Fixation of the acetabular cup in cemented total hip replacement: improving the anchorage hole profile using finite element method
.
Technol Health Care
vol.
8
,
(
6
)
343
-
355
.
Kobayashi E, Doi H, Yoneyama T, Hamanaka H, Gibson IR, Best SM, Shelton JC, Bonfield W
(
1998
)
.
Influence of aging heat treatment on mechanical properties of biomedical Ti-Zr based ternary alloys containing niobium
.
J Mater Sci Mater Med
vol.
9
,
(
11
)
625
-
630
.
Mo N, Shelton JC
(
1998
)
.
Laser speckle photography to measure surface displacements on cortical bone--verification of an automated analysis system
.
Med Eng Phys
vol.
20
,
(
8
)
594
-
601
.
Katz DM, Blatcher S, Shelton JC
(
1998
)
.
Quantification of holographic fringe data: comparison of intact and implanted femurs
.
Med Eng Phys
vol.
20
,
(
2
)
114
-
123
.
Kobayashi E, Doi H, Yoneyama T, Hamanaka H, Best SM, Shelton JC, Bonfield W
(
1996
)
.
Alloy-design of titanium-zirconium based alloys containing niobium as biomedical materials
.
Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
vol.
2
,
Gong F, Swain P, Kadirkamanathan S, Hepworth C, Laufer J, Shelton J, Mills T
(
1996
)
.
Cutting thread at flexible endoscopy
.
Gastrointest Endosc
vol.
44
,
(
6
)
667
-
674
.
Forrest DJ, Shelton JC, Gregson PJ
(
1996
)
.
Fatigue failure in a plasma sprayed hydroxyapatite coated titanium alloy
.
Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
vol.
1
,
McDougall I, Gregson PJ, Shelton JC
(
1996
)
.
Multiaxial fatigue testing of medical grade titanium alloy
.
Transactions of the Annual Meeting of the Society for Biomaterials in conjunction with the International Biomaterials Symposium
vol.
1
,
Horgan LF, Shelton JC, O'Riordan DC, Moore DP, Winslet MC, Davidson BR
(
1996
)
.
Strengths and weaknesses of laparoscopic and open mesh inguinal hernia repair: a randomized controlled experimental study
.
Br J Surg
vol.
83
,
(
10
)
1463
-
1467
.
Shelton JC, Loukota RA
(
1996
)
.
Pull-out strength of screws from cortical bone in the maxillo-facial region
.
J MATER SCI-MATER M
vol.
7
,
(
4
)
231
-
235
.
Kadirkamanathan SS, Shelton JC, Hepworth CC, Laufer JG, Swain CP
(
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