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Research

Publications: Prof Rupert Pearse

Scheeren TWL, Bakker J, Kaufmann T, Annane D, Asfar P, Boerma EC, Cecconi M, Chew MS et al. ( 2021 ) . Current use of inotropes in circulatory shock . Annals of Intensive Care vol. 11 , ( 1 )
Mazzinari G, Serpa Neto A, Hemmes SNT, Hedenstierna G, Jaber S, Hiesmayr M, Hollmann MW, Mills GH et al. ( 2021 ) . The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a posthoc propensity score–weighted cohort analysis of the LAS VEGAS study . BMC Anesthesiology vol. 21 , ( 1 )
Prowle JR, Forni LG, Bell M, Chew MS, Edwards M, Grams ME, Grocott MPW, Liu KD et al. ( 2021 ) . Postoperative acute kidney injury in adult non-cardiac surgery: joint consensus report of the Acute Disease Quality Initiative and PeriOperative Quality Initiative . Nature Reviews Nephrology
Abbott TEF, Howell S, Pearse RM, Ackland GL ( 2021 ) . Mode of blood pressure monitoring and morbidity after noncardiac surgery: A prospective multicentre observational cohort study . European Journal of Anaesthesiology vol. 38 , ( 5 ) 468 - 476 .
Pearse RM, Ackland GL, Asai T, Hemmings HC ( 2021 ) . Preprints in perioperative medicine: immediacy for the greater good . British Journal of Anaesthesia vol. 126 , ( 5 ) 915 - 918 .
Cook TM, Kelly F, Pearse R, Nolan J ( 2021 ) . Anaesthesia research capacity: time for a rethink in light of the COVID-19 pandemic . Anaesthesia vol. 76 , ( 4 ) 574 - 575 .
Fowler A, Abbott TEF, Pearse RM ( 2021 ) . Can we safely continue to offer surgical treatments during the COVID-19 pandemic? . BMJ Quality and Safety vol. 30 , ( 4 ) 268 - 270 .
Wan YI, Bien Z, Apea VJ, Orkin CM, Dhairyawan R, Kirwan CJ, Pearse RM, Puthucheary ZA et al. ( 2021 ) . Acute Kidney Injury in COVID-19: multicentre prospective analysis of registry data . Clinical Kidney Journalsfab071- - sfab071- .
Robbins AJ, Fowler AJ, Haines RW, Pearse RM, Prowle JR, Puthucheary Z ( 2021 ) . Emergency hospital admissions associated with non-communicable diseases 1998-2018 in England, Wales and Scotland: an ecological study . Clinical Medicine vol. 21 , ( 2 ) e179 - e185 .
Wan YI, Patel A, Achary C, Hewson R, Phull M, Pearse RM ( 2021 ) . Postoperative infection and mortality following elective surgery in the International Surgical Outcomes Study (ISOS) . The British journal of surgery vol. 108 , ( 2 ) 220 - 227 .
Kluyts HL, Conradie W, Cloete E, Spijkerman S, Smith O, Alli A, Koto MZ, Montwedi OD et al. ( 2021 ) . Development of a Clinical Prediction Model for In-hospital Mortality from the South African Cohort of the African Surgical Outcomes Study . World Journal of Surgery vol. 45 , ( 2 ) 404 - 416 .
Fowler AJ, Dobbs TD, Wan YI, Laloo R, Hui S, Nepogodiev D, Bhangu A, Whitaker IS et al. ( 2021 ) . Resource requirements for reintroducing elective surgery during the COVID-19 pandemic: modelling study . The British journal of surgery vol. 108 , ( 1 ) 97 - 103 .
Apea VJ, Wan YI, Dhairyawan R, Puthucheary ZA, Pearse RM, Orkin CM, Prowle JR ( 2021 ) . Ethnicity and outcomes in patients hospitalised with COVID-19 infection in East London: an observational cohort study . BMJ Open vol. 11 , ( 1 ) e042140 - e042140 .
Gillies MA, Ghaffar S, Moppett IK, Docherty AB, Clarke S, Rea N, Stephen J, Keerie C et al. ( 2021 ) . A restrictive versus liberal transfusion strategy to prevent myocardial injury in patients undergoing surgery for fractured neck of femur: a feasibility randomised trial (RESULT-NOF) . British Journal of Anaesthesia vol. 126 , ( 1 ) 77 - 86 .
Wan YI, McGuckin D, Fowler AJ, Prowle JR, Pearse RM, Moonesinghe SR ( 2020 ) . Socioeconomic deprivation and long-term outcomes after elective surgery: analysis of prospective data from two observational studies . British Journal of Anaesthesia
Beattie WS, Lalu M, Bocock M, Feng S, Wijeysundera DN, Nagele P, Fleisher LA, Kurz A et al. ( 2020 ) . Systematic review and consensus definitions for the Standardized Endpoints in Perioperative Medicine (StEP) initiative: cardiovascular outcomes . British Journal of Anaesthesia
May S, Abbott TEF, Gutierrez Del Arroyo A, Reyes A, Martir G, Stephens RCM, Brealey D, Cuthbertson B et al. ( 2020 ) . MicroRNA signatures of perioperative myocardial injury after elective noncardiac surgery: a prospective observational mechanistic cohort study . British Journal of Anaesthesia vol. 125 , ( 5 ) 661 - 671 .
COVIDSurg Collaborative ( 2020 ) . Elective surgery cancellations due to the COVID-19 pandemic: global predictive modelling to inform surgical recovery plans . British Journal of Surgery
Apea V, Wan Y, Dhairyawan R, Puthucheary Z, Pearse R, Orkin C, Prowle J ( 2020 ) . Ethnicity and outcomes in patients hospitalised with COVID-19 infection in East London: an observational cohort study . medrxiv
Fowler AJ, Dobbs TD, Wan YI, Laloo R, Hui S, Nepogodiev D, Bhangu A, Whitaker IS et al. ( 2020 ) . Resource requirements for reintroducing elective surgery in England during the COVID-19 pandemic: a modelling study .
Mcnelly AS, Flower L, Stevens TJ, Fowler AJ, Pearse RM, Prowle J, Puthucheary ZA ( 2020 ) . Attitudes of multimorbid patients to surviving future acute illness and subsequent functional disability: A systematic review . medRxiv2020.06.03.20121293 - 2020.06.03.20121293 .
Fowler A, Dobbs T, Wan Y, Laloo R, Hui S, Nepogodiev D, Pearse RM, ABBOTT T ( 2020 ) . Estimated surgical requirements in England after COVID-19: a modelling study using hospital episode statistics .
Wan YI, Patel A, ABBOTT TEF, Achary C, Macdonald N, Duceppe E, Sessler DI, Szczeklik W et al. ( 2020 ) . Prospective observational study of postoperative infection and outcomes after noncardiac surgery: analysis of prospective data from the VISION cohort . British Journal of Anaesthesia
Bangash MN, Abbott TEF, Patel NSA, Hinds C, Thiemermann C, Pearse R ( 2020 ) . The Effect of β2-Adrenoceptor Agonists on Leucocyte-Endothelial Adhesion in a Rodent Model of Laparotomy and Endotoxemia . Frontiers in Immunology vol. 11 ,
Thomas S, Borges F, Bhandari M, de Beer J, Cuchí GU, Adili A, Winemaker M, Avram V et al. ( 2020 ) . Association between myocardial injury and cardiovascular outcomes of orthopaedic surgery: A vascular events in noncardiac surgery patients cohort evaluation (VISION) substudy . Journal of Bone and Joint Surgery - American Volume vol. 102 , ( 10 ) 880 - 888 .
Wan Y, Apea V, Dhairyawan R, Orkin C, Pearse RM, Prowle JR ( 2020 ) . ETHICAL: Ethnic Disparities In COVID-19 Admissions in east London .
Shaw S, Hughes G, Stephens T, Pearse R, Prowle J, Ashcroft RE, Avagliano E, Day J et al. ( 2020 ) . Understanding decision making about major surgery: protocol for a qualitative study of shared decision making by high-risk patients and their clinical teams . BMJ open vol. 10 , ( 5 )
ABBOTT T, Pearse R, Chew M ( 2020 ) . Prevention of postoperative pulmonary complications in the hypoxaemic patient - gathering the evidence for noninvasive respiratory support . European Journal of Anaesthesiology vol. 37 , ( 4 ) 263 - 263 .
Ackland GL, ABBOTT T, Jones TF, Leuwer M, Pearse R, Niebrzegowska E, Wragg A, Archbold A et al. ( 2020 ) . Early elevation in plasma high-sensitivity troponin T and morbidity after elective noncardiac surgery: prospective multicentre observational cohort study . British Journal of Anaesthesia
Duceppe E, Patel A, Chan MTV, Berwanger O, Ackland G, Kavsak PA, Rodseth R, Biccard B et al. ( 2020 ) . Preoperative n-terminal pro-b-type natriuretic peptide and cardiovascular events after noncardiac surgery: A cohort study . Annals of Internal Medicine vol. 172 , ( 2 ) 96 - 104 .
Fowler A, Prowle J, Pearse R, Cromwell D ( 2020 ) . Chronic disease within the NHS surgical population: An epidemiological study statistical analysis plan .
Turan A, Artis AS, Hanline C, Saha P, Maheshwari K, Kurz A, Devereaux PJ, Duceppe E et al. ( 2020 ) . Preoperative Vitamin D Concentration and Cardiac, Renal, and Infectious Morbidity after Noncardiac Surgery . Anesthesiology vol. 132 , ( 1 ) 121 - 130 .
Wan Y, McGuckin D, Fowler A, Prowle J, Pearse R, Moonesinghe R ( 2020 ) . Socioeconomic deprivation and surgical outcomes: ISOS and VISION-UK sub-study (Statistical Analysis Plan) .
Delisle M, Pradarelli JC, Panda N, Koritsanszky L, Sonnay Y, Lipsitz S, Pearse R, Harrison EM et al. ( 2020 ) . Variation in global uptake of the Surgical Safety Checklist . British Journal of Surgery vol. 107 , ( 2 ) e151 - e160 .
Wijeysundera D, Beattie WS, Hillis G, ABBOTT T, Shulman M, Ackland G, Mazer D, Myles P et al. ( 2019 ) . Integration of the Duke Activity Status Index into Preoperative Risk Evaluation: A Multicentre Prospective Cohort Study . British Journal of Anaesthesia
Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA et al. ( 2019 ) . Correction: Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies (PLoS ONE (2019) 14:8 (e0221277) DOI: 10.1371/journal.pone.0221277) . PLoS ONE vol. 14 , ( 12 )
Scheeren TWL, Bakker J, De Backer D, Annane D, Asfar P, Boerma EC, Cecconi M, Dubin A et al. ( 2019 ) . Current use of vasopressors in septic shock . Annals of Intensive Care vol. 9 , ( 1 )
Yang F, Walker S, Richardson G, Stephens T, Phull M, Thompson A, Pearse RM ( 2019 ) . Reply letter to: “A commentary on “cost-effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery, health economic evaluation” (int J Surg 2019; epub ahead of print)” . International Journal of Surgery vol. 72 , 252 - 253 .
Gillies MA, Ghaffar S, Harrison E, Haddow C, Smyth L, Walsh TS, Pearse RM, Lone NI ( 2019 ) . The association between ICU admission and emergency hospital readmission following emergency general surgery . Journal of the Intensive Care Society vol. 20 , ( 4 ) 316 - 326 .
Macdonald N, Pearse RM, Murray PT, Inzitari R, Doran P, Prowle JR ( 2019 ) . The role of goal-directed therapy in the prevention of acute kidney injury after major gastrointestinal surgery: Substudy of the OPTIMISE trial . European Journal of Anaesthesiology vol. 36 , ( 12 ) 924 - 932 .
Yang F, Walker S, Richardson G, Stephens T, Phull M, Thompson A, Pearse RM, Enhanced Peri-Operative Care for High-risk patients (EPOCH) trial group ( 2019 ) . Cost-effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery: Learning from 15,856 patients . International Journal of Surgery vol. 72 , 25 - 31 .
Peden CJ, Stephens T, Martin G, Kahan BC, Thomson A, Everingham K, Kocman D, Lourtie J et al. ( 2019 ) . A national quality improvement programme to improve survival after emergency abdominal surgery: the EPOCH stepped-wedge cluster RCT .
Biccard BM, Bishop D, Dyer RA, Pearse RM ( 2019 ) . Anaesthesia providers and maternal mortality in Africa – Authors' reply . The Lancet Global Health vol. 7 , ( 10 )
Murray D, Pearse RM, Quiney N ( 2019 ) . Towards a coordinated national strategy to improve survival after emergency laparotomy . British Journal of Anaesthesia vol. 123 , ( 4 ) 399 - 401 .
Cashmore R, Fowler A, Pearse R ( 2019 ) . Post-operative intensive care: is it really necessary? . Intensive Care Medicine
Haines R, Zolfaghari P, Wan Y, PUTHUCHEARY Z, Pearse R, Prowle J ( 2019 ) . Elevated urea to creatinine ratio provides a biochemical signature of muscle catabolism and persistent critical illness after major trauma . Intensive Care Medicine
Stephens TJ, Peden CJ, Haines R, Grocott MPW, Murray D, Cromwell D, Johnston C, Hare S et al. ( 2019 ) . Hospital-level evaluation of the effect of a national quality improvement programme: time-series analysis of registry data . BMJ Quality and Safety
Ackland GL, Abbott TEF, Minto G, Clark M, Owen T, Prabhu P, May SM, Reynolds JA et al. ( 2019 ) . Heart rate recovery and morbidity after noncardiac surgery: Planned secondary analysis of two prospective, multi-centre, blinded observational studies . PLoS ONE vol. 14 , ( 8 )
Stephens T, Pearse RM ( 2019 ) . Learning from the EPOCH trial (Editorial). What we have learnt from a trial of an intervention to improve survival following emergency laparotomy . Anaesthesia Critical Care and Pain Medicine vol. 38 , ( 4 ) 321 - 322 .
The Vascular Events in Noncardiac Surgery Patients Cohort Evaluation (VISION) Study Investigators ( 2019 ) . Association between complications and death within 30 days after noncardiac surgery . Canadian Medical Association Journal vol. 191 , ( 30 ) E830 - E837 .
Fowler AJ, ABBOTT T, PROWLE J, PEARSE R ( 2019 ) . Age of patients undergoing surgery . British Journal of Surgery
Haller G, Bampoe S, Cook T, Fleisher LA, Grocott MPW, Neuman M, Story D, Myles PS et al. ( 2019 ) . Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine initiative: clinical indicators . British Journal of Anaesthesia
Pearse R ( 2019 ) . Post-surgery mortality in Poland – Author's reply . The Lancet vol. 393 , ( 10185 ) 2034 - 2035 .
ABBOTT TEF, PEARSE RM, beattie S, Phull M, Beilstein C, Raj A, Grocott M, Cuthbertson B et al. ( 2019 ) . Chronotropic incompetence and myocardial injury after non-cardiac surgery: planned secondary analysis of a prospective observational international cohort study . BJA: British Journal of Anaesthesia vol. 123 , ( 1 ) 17 - 26 .
Kocman D, Stöckelová T, Pearse R, Martin G ( 2019 ) . Neither magic bullet nor a mere tool: negotiating multiple logics of the checklist in healthcare quality improvement . Sociology of Health and Illness vol. 41 , ( 4 ) 755 - 771 .
PEARSE RM, Peden C, STEPHENS T, Martin G, KAHAN B, Thomson A, Rivett K, Wells D et al. ( 2019 ) . Effectiveness of a national quality improvement programme to improve survival after emergency abdominal surgery: A stepped-wedge cluster randomised trial . Lancet
Wijeysundera DN, Cuthbertson BH, Pearse RM, Myles PS ( 2019 ) . Functional capacity and preoperative risk evaluation – Authors' reply . The Lancet vol. 393 , ( 10181 ) 1593 - 1594 .
Bishop D, Dyer RA, Maswime S, Rodseth RN, van Dyk D, Kluyts HL, Tumukunde JT, Madzimbamuto FD et al. ( 2019 ) . Maternal and neonatal outcomes after caesarean delivery in the African Surgical Outcomes Study: a 7-day prospective observational cohort study . The Lancet Global Health vol. 7 , ( 4 ) e513 - e522 .
Edwards MR, Forbes G, MacDonald N, Berdunov V, Mihaylova B, Dias P, Thomson A, Grocott MP et al. ( 2019 ) . Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery . BMJ Open vol. 9 , ( 1 ) e023455 - e023455 .
Ryan EG, Harrison EM, Pearse RM, Gates S ( 2019 ) . Perioperative haemodynamic therapy for major gastrointestinal surgery: The effect of a Bayesian approach to interpreting the findings of a randomised controlled trial . BMJ Open vol. 9 , ( 3 )
Manou-Stathopoulou V, Abbott TEF, May SM, Cuthbertson BH, Wijeysundera DN, Pearse RM, Ackland GL ( 2019 ) . Perioperative plasma cortisol levels and myocardial injury after non-cardiac surgery . British Journal of Anaesthesia . vol. 122 , e45 - e46 .
May SM, Abbott TEF, Del Arroyo AG, Cuthbertson BH, Wijeysundera DN, Pearse RM, Ackland GL ( 2019 ) . Serum microRNAs and perioperative myocardial injury . British Journal of Anaesthesia . vol. 122 ,
ABBOTT TEF, PEARSE R ( 2019 ) . Depth of Anesthesia and Postoperative Delirium . JAMA - Journal of the American Medical Association vol. 321 , ( 5 ) 459 - 460 .
Biais M, Pearse R ( 2019 ) . Perioperative haemodynamic therapy: Why are recommendations not being adopted? . Anaesthesia Critical Care and Pain Medicine vol. 38 , ( 1 ) 5 - 7 .
ABBOTT TEF, Greaves K, PEARSE RM, Writing committee for the International Surgical Outcomes Study (ISOS) group ( 2019 ) . Prospective observational cohort study on grading the severity of postoperative complications in global surgery research . British Journal of Surgery vol. 106 , e73 - e80 .
Abbott TEF, Pearse RM, Cuthbertson BH, Wijeysundera DN, Ackland GL ( 2019 ) . Cardiac vagal dysfunction and myocardial injury after non-cardiac surgery: a planned secondary analysis of the measurement of Exercise Tolerance before surgery study . British Journal of Anaesthesia
Wan Y, Patel A, Achary C, Hewson R, Phull M, Pearse R ( 2019 ) . International Surgical Outcomes Study (ISOS) sub-study: post-operative infection (Statistical Analysis Plan) .
Edwards MR, Pearse RM ( 2019 ) . Perioperative Haemodynamic Optimisation . Hemodynamic Monitoring ,
Miller TE, Pearse RM ( 2019 ) . Perioperative fluid management: moving toward more answers than questions-a commentary on the RELIEF study . Perioper Med (Lond) vol. 8 ,
Barnes J, Hunter J, Harris S, Shankar-Hari M, Diouf E, Jammer I, Kalkman C, Klein AA et al. ( 2019 ) . Systematic review and consensus definitions for the Standardised Endpoints in Perioperative Medicine (StEP) initiative: infection and sepsis . British Journal of Anaesthesia
Dutoit L, Kluyts HL, Gobin V, Sani CM, Zoumenou E, Omigbodun AO, Amanor-Boadu SD, Zimogo S et al. ( 2019 ) . The African surgical outcomes-2 (Asos-2) pilot trial, a mixed-methods implementation study . Southern African Journal of Anaesthesia and Analgesia vol. 25 , ( 1 ) 14 - 31 .
Shulman MA, Cuthbertson BH, Wijeysundera DN, Pearse RM, Thompson B, Torres E, Ambosta A, Wallace S et al. ( 2019 ) . Using the 6-minute walk test to predict disability-free survival after major surgery . British Journal of Anaesthesia vol. 122 , ( 1 ) 111 - 119 .
Stephens TJ, Peden CJ, Pearse RM, Shaw SE, Abbott TEF, Jones EL, Kocman D, Martin G ( 2018 ) . Correction: Improving care at scale: Process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial). [Implement Sci. (2018), 13 (142)] DOI: 10.1186/s13012-018-0823-9 . Implementation Science vol. 13 , ( 1 )
Simonis FD, Barbas CSV, Artigas-Raventós A, Canet J, Determann RM, Anstey J, Hedenstierna G, Hemmes SNT et al. ( 2018 ) . Potentially modifiable respiratory variables contributing to outcome in ICU patients without ARDS: a secondary analysis of PRoVENT . Annals of Intensive Care vol. 8 , ( 1 )
Kluyts HL, le Manach Y, Munlemvo DM, Madzimbamuto F, Basenero A, Coulibaly Y, Rakotoarison S, Gobin V et al. ( 2018 ) . The ASOS Surgical Risk Calculator: development and validation of a tool for identifying African surgical patients at risk of severe postoperative complications . British Journal of Anaesthesia vol. 121 , ( 6 ) 1357 - 1363 .
Stephens TJ, Peden CJ, Pearse RM, Shaw SE, Abbott TEF, Jones E, Kocman D, Martin G et al. ( 2018 ) . Improving care at scale: Process evaluation of a multi-component quality improvement intervention to reduce mortality after emergency abdominal surgery (EPOCH trial) . Implementation Science vol. 13 , ( 1 )
Chaudery H, MacDonald N, Ahmad T, Chandra S, Tantri A, Sivasakthi V, Mansor M, Matos R et al. ( 2018 ) . Acute Kidney Injury and Risk of Death After Elective Surgery: Prospective Analysis of Data From an International Cohort Study . Anesth Analg
de Nadal M, Pérez-Hoyos S, Montejo-González JC, Pearse R, Aldecoa C ( 2018 ) . Intensive care admission and hospital mortality in the elderly after non-cardiac surgery . Medicina Intensiva vol. 42 , ( 8 ) 463 - 472 .
Fowler AJ, AHMAD T, ABBOTT T, TORRANCE H, PEARSE R, Wouters PF, De Hert S, Lobo SM et al. ( 2018 ) . Association of preoperative anaemia with postoperative morbidity and mortality: an observational cohort study in low-, middle-, and high-income countries . British Journal of Anaesthesia vol. 121 , ( 6 ) 1227 - 1235 .
Bloom B, Thomas S, Ahrensberg JM, Weaver R, Fowler A, Bestwick J, Harris T, Pearse R ( 2018 ) . A systematic review and meta-analysis of return to work after mild Traumatic brain injury . Brain Inj1 - 14 .
Ackland GL, Abbott TEF, Cain D, Edwards MR, Sultan P, Karmali SN, Fowler AJ, Whittle JR et al. ( 2018 ) . Preoperative systemic inflammation and perioperative myocardial injury: prospective observational multicentre cohort study of patients undergoing non-cardiac surgery . British Journal of Anaesthesia
TORRANCE H, LONGBOTTOM R, VIVIAN M, Lalabekyan B, ABBOTT TEF, ACKLAND GL, HINDS CJ, PEARSE RM et al. ( 2018 ) . Post-operative immune suppression is mediated via reversible, Interleukin-10 dependent pathways in circulating monocytes following major abdominal surgery . PLoS ONE vol. 13 , ( 9 )
Hewitt Smith A, Bulamba F, Olupot C, Musana F, Ochieng JP, Lipnick MS, Pearse RM ( 2018 ) . Surgical outcomes in eastern Uganda: A one-year cohort study . Southern African Journal of Anaesthesia and Analgesia vol. 24 , ( 5 ) 122 - 127 .
Greenberg L, Jairath V, Pearse R, Kahan BC ( 2018 ) . Prespecification of statistical analysis approaches in published clinical trial protocols was inadequate . Journal of Clinical Epidemiology vol. 101 , 53 - 60 .
Ackland GL, Abbott TF, Pearse RM, Investigators VEIN-CSPCE-U ( 2018 ) . Preoperative systemic inflammation and myocardial injury in non-cardiac surgery . British Journal of Anaesthesia . vol. 121 , e20 - e21 .
Gillies MA, Pearse R, Chew MS ( 2018 ) . Peri-operative goal-directed therapy . European Journal of Anaesthesiology vol. 35 , ( 7 ) 467 - 468 .
Pearse RM, Hopkins PM ( 2018 ) . Where audit meets science: role of reporting and recommendations guidelines in service evaluations . British Journal of Anaesthesia vol. 121 , ( 1 ) 118 - 120 .
Wijeysundera D, PEARSE R, shulman M, ABBOTT TEF, Torres E, Ambosta A, Bernard C, Granton J et al. ( 2018 ) . Assessment of functional capacity before major non-cardiac surgery: an international, prospective cohort study . Lancet vol. 391 , ( 10140 ) 2631 - 2640 .
WALKER S, ABBOTT TEF, Brown K, PEARSE R, ACKLAND G ( 2018 ) . Perioperative management of angiotensin-converting enzyme inhibitors and/or angiotensin receptor blockers: a survey of perioperative medicine practitioners . PeerJ
Lurati Buse G, Manns B, Lamy A, Guyatt G, Polanczyk CA, Chan MTV, Wang CY, Villar JC et al. ( 2018 ) . Troponin T monitoring to detect myocardial injury after noncardiac surgery: a cost–consequence analysis . Canadian Journal of Surgery vol. 61 , ( 3 ) 185 - 194 .
Walker S, Abbott T, Brown K, Pearse R, Ackland G ( 2018 ) . Contemporary perioperative management of ACE-inhibitors and angiotensin receptor blockers . British Journal of Anaesthesia . vol. 120 , e24 - e25 .
Vincent JL, Einav S, Pearse R, Jaber S, Kranke P, Overdyk FJ, Whitaker DK, Gordo F et al. ( 2018 ) . Improving detection of patient deterioration in the general hospital ward environment . European Journal of Anaesthesiology vol. 35 , ( 5 ) 325 - 333 .
Kahan BC, Morris TP, Harris E, Pearse R, Hooper R, Eldridge S ( 2018 ) . Re-randomization increased recruitment and provided similar treatment estimates as parallel designs in trials of febrile neutropenia . Journal of Clinical Epidemiology vol. 97 , 14 - 19 .
Buggy DJ, Freeman J, Johnson MZ, Leslie K, Riedel B, Sessler DI, Kurz A, Gottumukkala V et al. ( 2018 ) . Systematic review and consensus definitions for standardised endpoints in perioperative medicine: postoperative cancer outcomes . British Journal of Anaesthesia
ABBOTT TEF, Fowler A, Pelosi P, Garna de Abru M, Moller A, Canet J, Creagh-Brown B, Mythen M et al. ( 2018 ) . A systematic review and consensus definitions for standardised end-points in perioperative medicine: pulmonary complications . British Journal of Anaesthesia
Wijeysundera DN, Pearse R, Shulman M, Abbott T, Grocott MP, Myles P, Cuthbertson B ( 2018 ) . ASSESSMENT OF FUNCTIONAL CAPACITY BEFORE MAJOR ELECTIVE NONCARDIAC SURGERY: AN INTERNATIONAL MULTICENTER PROSPECTIVE COHORT STUDY . ANESTHESIA AND ANALGESIA . vol. 126 , 585 - 587 .
Yeung J, Gillies MA, Pearse RM ( 2018 ) . Pragmatic trials in peri-operative medicine: why, when and how? . Anaesthesia
PROWLE JR ( 2018 ) . Acute Kidney Injury in Trauma Patients Admitted to Critical Care: Development and Validation of a Diagnostic Prediction Model . Scientific Reports
PEARSE RM ( 2018 ) . Perioperative patient outcomes in the African Surgical Outcomes Study: a 7-day prospective observational cohort study . Lancet
ackland GL, ABBOTT T, Pearse RM, Karmali S, Whittle J, Minto G ( 2018 ) . Arterial pulse pressure and postoperative morbidity in high-risk surgical patients . British Journal of Anaesthesia vol. 120 , ( 1 ) 94 - 100 .
Neto AS, Da Costa LGV, Hemmes SNT, Canet J, Hedenstierna G, Jaber S, Hiesmayr M, Hollmann MW et al. ( 2018 ) . The LAS VEGAS risk score for prediction of postoperative pulmonary complications: An observational study . European Journal of Anaesthesiology vol. 35 , ( 9 ) 691 - 701 .
ABBOTT T, Ahmad T, Phull M, Fowler A, Hewson R, Biccard B, Chew M, Gillies M et al. ( 2018 ) . The surgical safety checklist and patient outcomes after surgery: a prospective observational cohort study, systematic review and meta-analysis . British Journal of Anaesthesia vol. 120 , ( 1 ) 146 - 155 .
MacDonald N, Pearse RM ( 2017 ) . Are we close to the ideal intravenous fluid? . British Journal of Anaesthesia vol. 119 , i63 - i71 .
Moppett IK, Pearse RM ( 2017 ) . Evidence-based medicine: The clue is in the name . British Journal of Anaesthesia vol. 119 , ( 6 ) 1084 - 1086 .
ABBOTT T, pearse RM, Archbold RA, Ahmad T, Niebrzegowska E, Wragg A, Rodseth R, Devereaux PJ et al. ( 2017 ) . A Prospective International Multicentre Cohort Study of Intraoperative Heart Rate and Systolic Blood Pressure and Myocardial Injury After Noncardiac Surgery: Results of the VISION Study . Anesthesia and Analgesia vol. 126 , ( 6 ) 1936 - 1945 .
Vellinga NAR, Boerma EC, Koopmans M, Donati A, Dubin A, Shapiro NI, Pearse RM, van der Voort PHJ et al. ( 2017 ) . Mildly elevated lactate levels are associated with microcirculatory flow abnormalities and increased mortality: A microSOAP post hoc analysis . Critical Care vol. 21 , ( 1 )
Ghaffar S, Pearse RM, Gillies MA ( 2017 ) . ICU admission after surgery: Who benefits? . Current Opinion in Critical Care vol. 23 , ( 5 ) 424 - 429 .
Gillies MA, Sander M, Shaw A, Wijeysundera DN, Myburgh J, Aldecoa C, Jammer I, Lobo SM et al. ( 2017 ) . Current research priorities in perioperative intensive care medicine . Intensive Care Medicine vol. 43 , ( 9 ) 1173 - 1186 .
Szakmany T, Ditai J, Kirov M, Protsenko D, Osinaike B, Venara A, Demartines N, Hubner M et al. ( 2017 ) . In-hospital clinical outcomes after upper gastrointestinal surgery: Data from an international observational study . EJSO - European Journal of Surgical Oncology
Schultz MJ, Hemmes SNT, Neto AS, Binnekade JM, Canet J, Hedenstierna G, Jaber S, Hiesmayr M et al. ( 2017 ) . Epidemiology, practice of ventilation and outcome for patients at increased risk of postoperative pulmonary complications: LAS VEGAS - An observational study in 29 countries . European Journal of Anaesthesiology vol. 34 , ( 8 ) 492 - 507 .
Chaudery H, MacDonald N, Pearse RM, Prowle JR ( 2017 ) . Global Incidence and Associations of Acute Kidney Injury in the International Surgical Outcomes Study (ISOS) . vol. 119 , is. 2 , pp. E28 - E28 .
Ahmad T, Bouwman RA, Grigoras I, Aldecoa C, Hofer C, Hoeft A, Holt P, Fleisher LA et al. ( 2017 ) . Use of failure-to-rescue to identify international variation in postoperative care in low-, middle- and high-income countries: A 7-day cohort study of elective surgery . British Journal of Anaesthesia vol. 119 , ( 2 ) 258 - 266 .
ABBOTT T, Pearse R, Dobbs TD, Harrison EM, Gillies MA, Fowler AJ ( 2017 ) . Frequency of surgical treatment and related hospital procedures in the United Kingdom: A national ecological study using hospital episode statistics . British Journal Of Anaesthesia vol. 119 , ( 2 ) 249 - 257 .
ABBOTT T, pearse R, ahmad T, ackland G ( 2017 ) . Association between preoperative pulse pressure and perioperative myocardial injury: an international observational cohort study of patients undergoing non-cardiac surgery . British Journal Of Anaesthesia vol. 119 , ( 1 ) 78 - 86 .
ABBOTT T, Lee A, Pearse R, Ackland G, Minto G ( 2017 ) . Elevated preoperative heart rate is associated with cardiopulmonary and autonomic impairment in high-risk surgical patients . British Journal Of Anaesthesia vol. 119 , ( 1 ) 87 - 94 .
Martin GP, Kocman D, Stephens T, Peden CJ, Pearse RM, This study was carried out as part of a wider randomised controlled trial, EPOCH ( 2017 ) . Pathways to professionalism? Quality improvement, care pathways, and the interplay of standardisation and clinical autonomy . Sociol Health Illn
Gillies MA, Lone NI, Pearse RM, Haddow C, Smyth L, Parks RW, Walsh TS, Harrison EM ( 2017 ) . Effect of day of the week on short- and long-term mortality after emergency general surgery . British Journal of Surgery vol. 104 , ( 7 ) 936 - 945 .
ABBOTT T, Pearse RM ( 2017 ) . Saving money: an ideal driver for improved perioperative care? . Anaesth Crit Care Pain Med vol. 36 , ( 3 ) 147 - 148 .
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Hewson R, Pearse RM ( 2012 ) . Inotropic Therapy . Encyclopedia of Intensive Care Medicine ,
Bangash MN, Pearse RM ( 2012 ) . Microcirculation . Encyclopedia of Intensive Care Medicine ,
Terblanche M, Kruger P, di Gangi S, Gearay S, Gilfeather L, Ferguson ND, Pearse R, Beale R et al. ( 2012 ) . Risk factors for acute organ failure in intensive care unit patients who receive respiratory support in the absence of non-respiratory organ failure: an international prospective cohort study . CRITICAL CARE vol. 16 , ( 2 ) Article ARTN R61 ,
Davenport R, Manson J, De'Ath H, Platton S, Coates A, Allard S, Hart D, Pearse R et al. ( 2011 ) . Functional definition and characterization of acute traumatic coagulopathy . Crit Care Med vol. 39 , ( 12 ) 2652 - 2658 .
Pearse R, Holt P, Grocott M ( 2011 ) . Authors' reply to Petros and colleagues . BMJ (Online) vol. 343 , ( 7833 )
Pearse RM, Holt PJE, Grocott MPW ( 2011 ) . Managing perioperative risk in patients undergoing elective non-cardiac surgery . BMJ vol. 343 ,
James S, Jhanji S, Niebrzegowska E, Tarrell T, Smith AV, Pearse R ( 2011 ) . PERI-OPERATIVE MICROVASCULAR FLOW AND CARDIO-PULMONARY EXERCISE TESTLNG IN HIGH RISK SURGICAL PATIENTS . INTENSIVE CARE MEDICINE . vol. 37 , S132 - S132 .
Kavsak PA, Walsh M, Srinathan S, Thorlacius L, Buse GL, Botto F, Pettit S, McQueen MJ et al. ( 2011 ) . High sensitivity troponin T concentrations in patients undergoing noncardiac surgery: A prospective cohort study . Clinical Biochemistry vol. 44 , ( 12 ) 1021 - 1024 .
Frith D, Baptista ML, Cohen M, Pearse R, Thiemermann C, Brohi K ( 2011 ) . Experimental acute traumatic coagulopathy is due to systemic activation of protein c during hypoperfusion . JOURNAL OF THROMBOSIS AND HAEMOSTASIS vol. 9 , 481 - 481 .
MacDonald N, Pearse RM ( 2011 ) . Peri-operative hemodynamic therapy: only large clinical trials can resolve our uncertainty . Crit Care vol. 15 , ( 3 )
Pearse RM, Rhodes A, Moreno R, Pelosi P, Spies C, Vallet B, Metnitz P, Bauer P et al. ( 2011 ) . EuSOS: European surgical outcomes study . Eur J Anaesthesiol vol. 28 , ( 6 ) 454 - 456 .
Davenport R, Manson J, De'Ath H, Platton S, Coates A, Allard S, Hart D, Pearse R et al. ( 2011 ) . Point of care diagnostics for the rapid identification of acute traumatic coagulopathy and prediction of massive trauma haemorrhage . BRITISH JOURNAL OF SURGERY . vol. 98 , 7 - 7 .
Pearse R, Holt P, Grocott M ( 2011 ) . Authors' reply to Petros and colleagues . BMJ vol. 343 ,
Frith D, Baptista ML, Cohen MJ, Pearse R, Thiemermann C, Brohi K ( 2011 ) . EXPERIMENTAL ACUTE TRAUMATIC COAGULOPATHY: INITIATED BY HYPOPERFUSION, MODULATED BY THE PROTEIN C PATHWAY . SHOCK vol. 36 , 16 - 17 .
Davenport R, Curry N, Manson J, De'Ath H, Coates A, Rourke C, Pearse R, Stanworth S et al. ( 2011 ) . Hemostatic effects of fresh frozen plasma may be maximal at red cell ratios of 1:2 . J Trauma vol. 70 , ( 1 ) 90 - 95 .
Correa T, Kindler R, Brandt S, Gorrasi J, Regueira T, Bracht H, Porta F, Takala J et al. ( 2011 ) . Impact of hepatic venous oxygen efflux and carotid blood flow on the difference between mixed and central venous oxygen saturation . Critical care (London, England) vol. 15 , ( Suppl 1 ) P35 - P35 .
Martin-Loeches I, Lisboa T, Rhodes A, Moreno RP, Silva E, Sprung C, Chiche JD, Barahona D et al. ( 2011 ) . Use of early corticosteroid therapy on ICU admission in patients affected by severe pandemic (H1N1)v influenza A infection . Intensive Care Medicine vol. 37 , ( 2 ) 272 - 283 .
Frith D, Stanworth S, Gaarder C, Maegele M, Goslings C, Johansson P, Allard S, Cohen M et al. ( 2010 ) . Acute traumatic coagulopathy is dependent upon injury load and shock . BRITISH JOURNAL OF SURGERY vol. 97 , 39 - 40 .
Martin-Loeches I, Lisboa T, Rhodes A, Moreno R, Silva E, Sprung C, Chiche J, Barahona D et al. ( 2010 ) . USE OF CORTICOSTEROID THERAPY IN PATIENTS AFFECTED BY SEVERE PANDEMIC (H1N1)V INFLUENZA A INFECTION . INTENSIVE CARE MEDICINE . vol. 36 , S319 - S319 .
Pearse RM ( 2010 ) . Another inconvenient truth: Meeting the challenge of preventing poor surgical outcomes . Current Opinion in Critical Care vol. 16 , ( 4 ) 337 - 338 .
Martin GS, Pearse R ( 2010 ) . Current Opinion in Critical Care: Editorial introductions . Current Opinion in Critical Care vol. 16 , ( 4 )
Rampal T, Jhanji S, Pearse RM ( 2010 ) . Using oxygen delivery targets to optimize resuscitation in critically ill patients . Curr Opin Crit Care vol. 16 , ( 3 ) 244 - 249 .
Spanos A, Jhanji S, Vivian-Smith A, Harris T, Pearse RM ( 2010 ) . EARLY MICROVASCULAR CHANGES IN SEPSIS AND SEVERE SEPSIS . SHOCK vol. 33 , ( 4 ) 387 - 391 .
Pearse RM ( 2010 ) . Water, taken in moderation, cannot hurt anybody (Mark Twain 1835-1910) . J PHYSIOL-LONDON vol. 588 , ( 2 ) 281 - 282 .
Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds CJ, Pearse RM ( 2010 ) . Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: a randomised controlled trial . Crit Care vol. 14 , ( 4 )
Grocott MPW, Pearse RM ( 2010 ) . Prognostic studies of perioperative risk: Robust methodology is needed . British Journal of Anaesthesia vol. 105 , ( 3 ) 243 - 245 .
Frith D, Cohen M, Pearse R, Thiemermann C, Brohi K ( 2010 ) . Rodent coagulation responses to trauma and haemorrhagic shock . INFLAMMATION RESEARCH . vol. 59 , S26 - S27 .
Pearse R, Bennett D, Hinds C ( 2009 ) . Dopexamine and survival: Areas of consistency . Anaesthesia vol. 64 , ( 11 )
Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds CJ, Pearse RM ( 2009 ) . A RANDOMISED CONTROLLED TRIAL OF THE EFFECTS OF POST-OPERATIVE HAEMODYNAMIC OPTIMISATION ON MICROVASCULAR FLOW, TISSUE OXYGENATION AND INFLAMMATORY MARKERS AFTER MAJOR ABDOMINAL SURGERY . INTENSIVE CARE MEDICINE . vol. 35 , 213 - 213 .
Shepherd SJ, Pearse RM ( 2009 ) . Role of Central and Mixed Venous Oxygen Saturation Measurement in Perioperative Care . ANESTHESIOLOGY vol. 111 , ( 3 ) 649 - 656 .
Powell-Tuck J, Gosling P, Lobo DN, Carlson GL, Allison SP, Gore M, Lewington AJ, Pearse RL et al. ( 2009 ) . Intravenous fluids in surgery: Authors of guideline respond . BMJ (Online) vol. 339 , ( 7715 )
Jhanji S, Pearse RM ( 2009 ) . The use of early intervention to prevent postoperative complications . Curr Opin Crit Care vol. 15 , ( 4 ) 349 - 354 .
Jhanji S, Stirling S, Patel N, Hinds CJ, Pearse RM ( 2009 ) . The effect of increasing doses of norepinephrine on tissue oxygenation and microvascular flow in patients with septic shock . Crit Care Med vol. 37 , ( 6 ) 1961 - 1966 .
Jhanji S, Lee C, Watson D, Hinds C, Pearse RM ( 2009 ) . Microvascular flow and tissue oxygenation after major abdominal surgery: association with post-operative complications . Intensive Care Med vol. 35 , ( 4 ) 671 - 677 .
Frith D, Chesebro B, Pittet JF, Cohen MJ, Thiemermann C, Pearse R, Brohi K ( 2009 ) . ACUTE TRAUMATIC COAGULOPATHY IS DRIVEN BY SYSTEMIC HYPOPERFUSION INDEPENDENT OF HYPOTENSION AND HAEMORRHAGE VOLUME . SHOCK . vol. 32 , 9 - 9 .
Maddison B, Wolff C, Findlay G, Radermacher P, Hinds C, Pearse RM ( 2009 ) . Comparison of three methods of extravascular lung water volume measurement in patients after cardiac surgery . Crit Care vol. 13 , ( 4 )
Jhanji S, Stirling S, Patel NSA, Hinds CJ, Pearse RM ( 2009 ) . EFFECT OF INCREASING DOSES OF NOREPINEPHRINE ON TISSUE OXYGENATION AND MICROVASCULAR PERFUSION IN SEPTIC SHOCK . SHOCK . vol. 32 , 2 - 2 .
Pearse RM ( 2009 ) . Extending the role of lactate measurement into the prehospital environment . Crit Care vol. 13 , ( 1 )
Morris CG, Pearse RM ( 2009 ) . Pro-con debate: We should not measure cardiac output in critical care . Media, War and Conflict vol. 10 , ( 1 ) 8 - 12 .
Powell-Tuck J, Allison SP, Gosling P, Lobo DN, Carlson GL, Gore M, Lewington AJ, Pearse RM et al. ( 2009 ) . Summary of the British Consensus Guidelines on Intravenous Fluid Therapy for Adult Surgical Patients (GIFTASUP) - For comment . Media, War and Conflict vol. 10 , ( 1 ) 13 - 15 .
Davenport R, Coates A, Allard S, Pasi J, MacCallum P, Stanworth S, Thiemermann C, Pearse R et al. ( 2009 ) . TRAUMA HAEMORRHAGE: EVOLVING ROLE OF ROTEM FOR PREDICTING TRANSFUSION REQUIREMENTS . SHOCK . vol. 32 , 15 - 15 .
Maddison B, Giudici R, Calzia E, Wolff C, Hinds C, Radermacher P, Pearse RM ( 2008 ) . Extravascular lung water volume measurement by a novel lithium-thermal indicator dilution method: comparison of three techniques to post-mortem gravimetry . Intensive Care Med vol. 34 , ( 11 ) 2106 - 2111 .
Jhanji S, Thomas B, Ely A, Watson D, Hinds CJ, Pearse RM ( 2008 ) . Mortality and utilisation of critical care resources amongst high-risk surgical patients in a large NHS trust . Anaesthesia vol. 63 , ( 7 ) 695 - 700 .
Pearse RM, Belsey JD, Cole JN, Bennett ED ( 2008 ) . Effect of dopexamine infusion on mortality following major surgery: Individual patient data meta-regression analysis of published clinical trials . CRIT CARE MED vol. 36 , ( 4 ) 1323 - 1329 .
Jhanji S, Dawson J, Pearse RM ( 2008 ) . Cardiac output monitoring: basic science and clinical application . Anaesthesia vol. 63 , ( 2 ) 172 - 181 .
Maddison B, Findlay G, Radermacher P, Hinds C, Pearse RM ( 2008 ) . Intrathoracic blood volume measurement: A comparison of transpulmonary lithium indicator dilution with indocyanine green indicator dilution . SHOCK . vol. 29 , 63 - 63 .
Maddison B, Wolff C, Findlay G, Calzia E, Hinds C, Pearse R ( 2008 ) . Intrathoracic blood volume measurement: comparison of transpulmonary lithium indicator dilution with indocyanine green indicator dilution . Critical care (London, England) vol. 12 , ( Suppl 2 ) P103 - P103 .
Jhanji S, Lee C, Watson D, Hinds CJ, Pearse RM ( 2008 ) . Tissue oxygenation and microvascular flow after major abdominal surgery . SHOCK . vol. 29 , 64 - 64 .
Frith D, Chesebro B, Patel N, Thiemermann C, Brohi K, Cohen M, Pearse R ( 2008 ) . Towards a mouse model for acute coagulopathy of trauma/shock . SHOCK . vol. 29 , 6 - 6 .
Maddison B, Best T, Pearse RM ( 2007 ) . Extravascular lung water measurement . Intensive Care Medicine: Annual Update 2007 ,
Pearse RM, Young JD ( 2007 ) . Steroids to prevent postextubation laryngeal oedema . Lancet vol. 369 , ( 9567 ) 1060 - 1061 .
Pearse RM, Dawson D, Fawcett J, Rhodes A, Grounds RM, Bennett D ( 2007 ) . The incidence of myocardial injury following post-operative Goal Directed Therapy . BMC Cardiovasc Disord vol. 7 ,
Belsey J, Pearse R, Cole J, Bennet D ( 2007 ) . An individual patient meta-analysis of clinical trials using dopexamine to increase oxygen delivery in high-risk surgical patients . Critical care (London, England) vol. 11 , ( Suppl 2 ) P315 - P315 .
Maddison B, Best T, Pearse RM ( 2007 ) . Extravascular Lung Water Measurement . Intensive Care Medicine , vol. 2007 ,
McGinley A, Pearse RM ( 2007 ) . Medical emergency teams: implementation and outcome measurement . Critical care (London, England) vol. 11 , ( 2 ) 307 - 307 .
Maddison B, Best T, Wolff C, Jones P, Hinds C, Pearse R ( 2007 ) . Transpulmonary lithium indicator dilution: a new method of intrathoracic blood volume measurement . Critical care (London, England) vol. 11 , ( Suppl 2 ) P295 - P295 .
Collinson PO, Wort S, Bruce H, Rhodes A, Pearse R, Bennett ED ( 2006 ) . Plasma DNA concentration as a predictor of mortality and sepsis in general intensive care patients . CLINICAL CHEMISTRY . vol. 52 , A12 - A12 .
Pearse RM, Harrison DA, James P, Watson D, Hinds C, Rhodes A, Grounds RM, Bennett ED ( 2006 ) . Identification and characterisation of the high-risk surgical population in the United Kingdom . Crit Care vol. 10 , ( 3 )
Pearse RM, Hinds CJ ( 2006 ) . Should we use central venous saturation to guide management in high-risk surgical patients? . Crit Care vol. 10 , ( 6 )
Wort SJ, Rhodes A, Thomas H, Pearse R, Collinson P, Bennett ED ( 2005 ) . The role of plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients . THORAX . vol. 60 , II116 - II116 .
Bates CJ, Pearse R ( 2005 ) . Use of hydrogen peroxide vapour for environmental control during a Serratia outbreak in a neonatal intensive care unit . J Hosp Infect vol. 61 , ( 4 ) 364 - 366 .
Jin DK, Young LM, Vincent L, Gelbshtein U, Pekle K, Lam G, Shido K, Cho HJ et al. ( 2005 ) . Multimodular analysis of angiogenic biomarkers in the primary treatment of multiple myeloma: Correlative studies of the BiRD trial . BLOOD . vol. 106 , 972A - 972A .
Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds RM, Bennett ED ( 2005 ) . Changes in central venous saturation after major surgery, and association with outcome . Critical care (London, England) vol. 9 , ( 6 )
Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds M, Bennnett D ( 2005 ) . Early goal directed therapy reduces morbidity and length of hospital stay following high-risk surgery . Critical care (London, England) vol. 9 , ( Suppl 1 ) P45 - P45 .
Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds RM, Bennett ED ( 2005 ) . Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial [ISRCTN38797445] . Critical care (London, England) vol. 9 , ( 6 )
Pearse RM, Rhodes A, Grounds RM ( 2004 ) . Clinical review: How to optimize management of high-risk surgical patients . Critical Care vol. 8 , ( 6 ) 503 - 507 .
Pearse RM ( 2004 ) . Equipment review . Critical Care vol. 8 , ( 3 ) 193 - 195 .
Pearse RM, Ikram K, Barry J ( 2004 ) . Equipment review: An appraisal of the LiDCO™ plus method of measuring cardiac output . Critical Care vol. 8 , ( 3 ) 190 - 193 .
Pearse R, Wort SJ ( 2004 ) . Acute respiratory distress syndrome (ARDS) . Clinical Intensive Care vol. 15 , ( 1 ) 37 - 42 .
Wort S, Rhodes A, Thomas H, Pearse R, Collinson P ( 2004 ) . Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients . Critical care (London, England) vol. 8 , ( Suppl 1 ) P187 - P187 .
Pearse R, Dawson D, Fawcett J, Wort S, Rhodes A, Grounds R ( 2004 ) . The relationship between central venous saturation and outcome following high-risk surgery . Critical care (London, England) vol. 8 , ( Suppl 1 ) P51 - P51 .
Pearse R, Wort SJ, Terblanche M, Rhodes A ( 2003 ) . Critical care clinical conundrums . Clinical Intensive Care vol. 14 , ( 3-4 ) 149 - 155 .
Pearse RM, Dawson D, Rhodes A, Grounds RM, Bennett ED ( 2003 ) . Low central venous saturation predicts post-operative mortality . INTENSIVE CARE MEDICINE . vol. 29 , S15 - S15 .
Dawson D, Pearse R, Rhodes A, Bennett D ( 2003 ) . Reliability of venous blood gas measurements in the recognition of the acutely ill patient . INTENSIVE CARE MEDICINE . vol. 29 , S178 - S178 .
Pearse RM, Draper A, Grounds RM ( 2003 ) . Non-invasive ventilation to avoid tracheal intubation in a patient with Guillain-Barré syndrome . British Journal of Anaesthesia vol. 91 , ( 6 ) 913 - 916 .
Pearse RM, Dana EC, Lanigan CJ, Pook JAR ( 2001 ) . Organisational failures in urgent and emergency surgery: A potential peri-operative risk factor . Anaesthesia vol. 56 , ( 7 ) 684 - 689 .
Pearse R ( 2001 ) . Inadequate pre-operative evaluation and preparation 1 . Anaesthesia vol. 56 , ( 4 )
Pearse RM, Mitra AV, Heymann TD ( 1999 ) . What the SHO really does . Journal of the Royal College of Physicians of London vol. 33 , ( 6 ) 553 - 556 .
Pearse R, Rajakulendran Y ( 1999 ) . Pre-operative fasting and administration of regular medications in adult patients presenting for elective surgery. Has the new evidence changed practice? . European Journal of Anaesthesiology vol. 16 , ( 8 ) 565 - 568 .
Lee CN, Vasilakis C, Kearney D, Pearse R, Millard PH ( 1998 ) . An analysis of admission, discharge and bed occupancy of stroke patients aged 65 and over in English hospitals . Health Care Management Science vol. 1 , ( 2 ) 151 - 157 .
Kelly RI, Pearse R, Bull RH, Leveque JL, de Rigal J, Mortimer PS ( 1995 ) . The effects of aging on the cutaneous microvasculature . Journal of the American Academy of Dermatology vol. 33 , ( 5 PART 1 ) 749 - 756 .