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Research

Publications: Prof Michael Philpott

Chew EGY, Lim TC, Leong MF, Liu X, Sia YY, Leong ST, Yan-Jiang BC, Stoecklin C et al. ( 2022 ) . Observations that suggest a contribution of altered dermal papilla mitochondrial function to androgenetic alopecia . Experimental Dermatology vol. 31 , ( 6 ) 906 - 917 .
Nourinovin S, Navarro-Cia M, Rahman MM, Philpott MP, Abbasi QH, Alomainy A ( 2022 ) . Terahertz Metastructures for Noninvasive Biomedical Sensing and Characterization in Future Health Care [Bioelectromagnetics] . IEEE Antennas and Propagation Magazine vol. 64 , ( 2 ) 60 - 70 .
Nourinovin S, Rahman MM, Jones RC, Philpott MP, Alomainy A ( 2022 ) . Impact of Drug Treatment on the Electromagnetic Properties of Basal Cell Carcinoma Cancer in the Terahertz Band . 2022 16th European Conference on Antennas and Propagation, EuCAP 2022 .
Nourinovin S, Rahman MM, Philpott MP, Alomainy A ( 2022 ) . Terahertz Characterisation of Artificially Cultured Oral Cancer with Stem Cell Lines for Healthcare Applications . 2022 IEEE International Symposium on Medical Measurements and Applications, MeMeA 2022 - Conference Proceedings .
Figlak K, Williams G, Bertolini M, Paus R, Philpott MP ( 2021 ) . Human hair follicles operate an internal Cori cycle and modulate their growth via glycogen phosphorylase . Scientific Reports vol. 11 , ( 1 )
Rahman MM, Herath D, Bladen JC, Atkar R, Pirzado MS, Harwood C, Philpott MP, Neill GW ( 2021 ) . Differential expression of phosphorylated MEK and ERK correlates with aggressive BCC subtypes . Carcinogenesis vol. 42 , ( 7 ) 975 - 983 .
Philpott MP ( 2021 ) . Pigmentation: Watching hair turn grey . eLife vol. 10 ,
Tyler EJ, Gutierrez del Arroyo A, Hughes BK, Wallis R, Garbe JC, Stampfer MR, Koh J, Lowe R et al. ( 2021 ) . Early growth response 2 (EGR2) is a novel regulator of the senescence programme . Aging Cell vol. 20 , ( 3 )
Vootukuri RS, Philpott MP, Trigiante G ( 2020 ) . Fluorimetric ex vivo quantification of protease debriding efficacy on natural substrate . Wound Repair and Regeneration vol. 28 , ( 6 ) 844 - 847 .
Evans EA, Sayers SR, Kodji X, Xia Y, Shaikh M, Rizvi A, Frame J, Brain SD et al. ( 2020 ) . Psoriatic skin inflammation induces a pre-diabetic phenotype via the endocrine actions of skin secretome . Molecular Metabolism vol. 41 ,
Lara R, Adinolfi E, Harwood CA, Philpott M, Barden JA, Di Virgilio F, McNulty S ( 2020 ) . P2X7 in Cancer: From Molecular Mechanisms to Therapeutics . Frontiers in Pharmacology vol. 11 ,
Philpott M ( 2020 ) . A new model of human telogen-anagen transformation helps decipher Wnt signalling in the human hair cycle . Br J Dermatol vol. 182 , ( 5 ) 1084 - 1084 .
Borhan R, Lee J, Youssef G, Bensussan A, Philpott M ( 2019 ) . Différence de signature génétique moléculaire des cellules du derme papillaire entre le cuir chevelu alopécique et le cuir chevelu non alopécique dans les cultures cellulaires bidimensionnelle, tridimensionnelle et co-culture avec les cellules souches mésenchymateuses dérivées des adipocytes . Annales de Dermatologie et de Vénéréologie vol. 146 , ( 12 )
Fang L, Trigiante G, Crespo-Otero R, Philpott MP, Jones CR, Watkinson M ( 2019 ) . An alternative modular 'click-SNAr-click' approach to develop subcellular localised fluorescent probes to image mobile Zn2+  . Organic and Biomolecular Chemistry
Fang L, Trigiante G, Crespo-Otero R, Hawes CS, Philpott M, Jones CR, Watkinson M ( 2019 ) . Endoplasmic reticulum targeting fluorescent probes to image mobile Zn2+ . Chemical Science
Youssef G, Cottoms H, Piper K, Gammon L, Knowles O, Lunt SA, Mackenzie I, Philpott M et al. ( 2019 ) . 585 Identifying cancer stem cells in patient specimens through high-content imaging - biological insights and prognostic potential . Journal of Investigative Dermatology . vol. 139 ,
Figlak K, Paus R, Williams G, Philpott M ( 2019 ) . 597 Outer root sheath is able to synthesise glycogen from lactate-investigating glycogen metabolism in human hair follicles . Journal of Investigative Dermatology . vol. 139 ,
Reddy SV, Philpott M, Trigiante G ( 2019 ) . 612 Targeted hair follicle delivery of hydrophilic molecules . Journal of Investigative Dermatology vol. 139 , ( 9 )
Reddy SV, Philpott M, Trigiante G ( 2019 ) . Targeted hair follicle delivery of hydrophilic molecules . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 139 , S320 - S320 .
Hochfeld LM, Broadley D, Botchkareva NV, Philpott MP, Schoch S, Betz RC, Noethen MM, Heilmann-Heimbach S ( 2019 ) . Evidence for a functional interaction between WNT10A and EBF1 in the development of androgenetic alopecia (AGA) . EUROPEAN JOURNAL OF HUMAN GENETICS . vol. 27 , 95 - 96 .
Zhang R, Yang K, Yang B, AbuAli NA, Hayajneh M, Philpott M, Abbasi QH, Alomainy A ( 2019 ) . Dielectric and Double Debye Parameters of Artificial Normal Skin and Melanoma . Journal of Infrared, Millimeter, and Terahertz Waves vol. 40 , ( 6 ) 657 - 672 .
Shah KF, Davis M, Peplow A, DeAngelis Y, Philpott M ( 2019 ) . 899 HIF1A stabilisation in the ORS of human hair follicles promotes aerobic glycolysis and synthesis of angiogenic factors . Journal of Investigative Dermatology vol. 139 , ( 5 )
Shah KF, Davis M, Peplow A, DeAngelis Y, Philpott M ( 2019 ) . HIF1A stabilisation in the ORS of human hair follicles promotes aerobic glycolysis and synthesis of angiogenic factors . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 139 , S155 - S155 .
Bladen JC, Wang J, Sangaralingam A, Moosajee M, Fitchett C, Chelala C, Beaconsfield M, O'Toole EA et al. ( 2018 ) . MicroRNA and transcriptome analysis in periocular Sebaceous Gland Carcinoma . Scientific Reports vol. 8 , ( 1 )
Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR, Hecker J, Javed A, Chew EGY et al. ( 2018 ) . GWAS meta-analysis yields novel insights into the biology of male-pattern baldness . EUROPEAN JOURNAL OF HUMAN GENETICS . vol. 26 , 761 - 762 .
Fang L, Trigiante G, Kousseff CJ, Crespo-Otero R, Philpott MP, Watkinson M ( 2018 ) . Biotin-tagged fluorescent sensor to visualize 'mobile' Zn2+ in cancer cells . Chem Commun (Camb)
Lee J, Bahta A, Bohgal R, Philpott M ( 2018 ) . Characterization of immortalized human balding and nonbalding dermal papilla cells . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E419 - E419 .
Milligan D, Newman J, Caley M, Wainwright L, Jenkins G, Philpott M, Bishop C ( 2018 ) . Development of a three-dimensional living skin equivalent to explore the influence of senescence on the skin ageing phenotype . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E420 - E420 .
Figlak K, Paus R, Philpott M ( 2018 ) . Dissecting the role of glycogen metabolism in human hair follicle biology . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E406 - E406 .
Shah K, Davis M, Philpott M ( 2018 ) . Hypoxia, hypoxia-inducible factor A and hair follicle metabolism . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E412 - E412 .
Vootukuri RS, Trigiante G, Philpott M ( 2018 ) . Novel biologically active proteases in Carica papaya ripe fruit extracts for medicinal use . BRITISH JOURNAL OF DERMATOLOGY . vol. 178 , E418 - E418 .
Rahman MM, Hazan A, Selway JL, Herath DS, Harwood CA, Pirzado MS, Atkar R, Kelsell DP et al. ( 2018 ) . A novel mechanism for activation of GLI1 by nuclear SMO that escapes anti-SMO inhibitors . Cancer Research vol. 78 , ( 10 ) 2577 - 2588 .
Kenny FN, Drymoussi Z, Delaine-Smith R, Kao AP, Laly AC, Knight MM, Philpott MP, Connelly JT ( 2018 ) . Tissue stiffening promotes keratinocyte proliferation through activation of epidermal growth factor signaling . Journal of Cell Science vol. 131 , ( 10 ) Article jcs215780 , 215780 - 215780 .
Evans E, Brain S, Philpott M, Caton P, Hannen R ( 2018 ) . 1005 The skin: A new player in the control of whole-body glucose homeostasis . Journal of Investigative Dermatology vol. 138 , ( 5 ) s170 - s170 .
Shah K, Davis M, Philpott M ( 2018 ) . 1328 HIF1A stabilisation in the human hair follicle promotes glycolysis . Journal of Investigative Dermatology vol. 138 , ( 5 )
Figlak K, Paus R, Philpott M ( 2018 ) . 1332 Understanding the role of glycogen metabolism in human hair follicle biology . Journal of Investigative Dermatology vol. 138 , ( 5 )
Hannen R, Leigh I, Philpott M ( 2018 ) . 717 Dysfunctional stress response in psoriatic keratinocytes . Journal of Investigative Dermatology . vol. 138 ,
Philpott MP ( 2018 ) . Culture of the human pilosebaceous unit, hair follicle and sebaceous gland . Experimental Dermatology vol. 27 , ( 5 ) 571 - 577 .
Hannen R, Leigh I, Philpott M ( 2018 ) . Dysfunctional stress response in psoriatic keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 138 , S122 - S122 .
Shah K, Davis M, Philpott M ( 2018 ) . HIF1A stabilisation in the human hair follicle promotes glycolysis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 138 , S226 - S226 .
Figlak K, Paus R, Philpott M ( 2018 ) . Understanding the role of glycogen metabolism in human hair follicle biology . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 138 , S226 - S226 .
Bladen JC, Moosajee M, Tracey-White D, Beaconsfield M, O’Toole EA, Philpott MP ( 2018 ) . Analysis of hedgehog signaling in periocular sebaceous carcinoma . Graefe's Archive for Clinical and Experimental Ophthalmology vol. 256 , ( 4 ) 853 - 860 .
Evans E, Kodji X, Sayers S, Xia Y, Brain S, Philpott M, Hannen R, Caton P ( 2018 ) . The skin: A novel regulator of whole-body glucose homeostasis . DIABETIC MEDICINE . vol. 35 , 53 - 54 .
Caton PW, Evans EA, Philpott MP, Hannen RF ( 2017 ) . Can the skin make you fat? A role for the skin in regulating adipose tissue function and whole-body glucose and lipid homeostasis . Current Opinion in Pharmacology vol. 37 , 59 - 64 .
Hannen RF, Asher S, Mannella V, Purdie K, Leigh I, Philpott M ( 2017 ) . 131 Stressed out keratinocytes, new insights into psoriasis lesion formation . Journal of Investigative Dermatology . vol. 137 ,
Figlak K, Paus R, Philpott M ( 2017 ) . 266 Glycogen metabolism and Cori cycle in human hair follicles . Journal of Investigative Dermatology . vol. 137 ,
Shah KF, Davis M, Philpott M ( 2017 ) . 280 Investigation into the role of HIF-1A stabilisation in hair follicle metabolism . Journal of Investigative Dermatology . vol. 137 ,
Vootukuri R, Trigiante G, Philpott M ( 2017 ) . 679 Wound Healing properties of OPAL A (patented Carica papaya fruit extract) . Journal of Investigative Dermatology . vol. 137 ,
Milligan D, Newman J, Caley M, Wainwright L, Jenkins G, Philpott M, Bishop C ( 2017 ) . 682 Development of a 3D living skin equivalent to explore the influence of senescence on the skin ageing phenotype . Journal of Investigative Dermatology . vol. 137 ,
Evans E, Kodji X, Sayers S, Brain S, Philpott M, Hannen R, Caton P ( 2017 ) . A novel skin-adipose tissue axis regulates pancreatic beta cell function . DIABETOLOGIA . vol. 60 , S12 - S12 .
Hannen R, Udeh-Momoh C, Upton J, Wright M, Michael A, Gulati A, Rajpopat S, Clayton N et al. ( 2017 ) . Dysfunctional Skin-Derived Glucocorticoid Synthesis Is a Pathogenic Mechanism of Psoriasis . Journal of Investigative Dermatology vol. 137 , ( 8 ) 1630 - 1637 .
Pantazi E, Gemenetzidis E, Teh MT, Reddy SV, Warnes G, Evagora C, Trigiante G, Philpott MP ( 2017 ) . GLI2 Is a Regulator of β-Catenin and Is Associated with Loss of E-Cadherin, Cell Invasiveness, and Long-Term Epidermal Regeneration . Journal of Investigative Dermatology vol. 137 , ( 8 ) 1719 - 1730 .
PHILPOTT MP, Ojeh N, Tomic-Canic M, Akgül B, Navsaria H ( 2017 ) . In vitro skin models to study epithelial regeneration from the hair follicle . PLoS ONE
Heilmann-Heimbach S, Herold C, Hochfeld LM, Hillmer AM, Nyholt DR, Hecker J, Javed A, Chew EGY et al. ( 2017 ) . Meta-analysis identifies novel risk loci and yields systematic insights into the biology of male-pattern baldness . Nature Communications vol. 8 ,
Evans EA, Sayers SR, Philpott MP, Hannen RF, Caton PW ( 2017 ) . A novel skin-adipose tissue axis regulates pancreatic beta cell function . vol. 34 , is. Special Issue 1 , pp. 42 - 42 . Abstract: java.sql.Clob org.hibernate.engine.jdbc.WrappedClob java.io.Serializable ,
Hannen RF, Perez P, Lightman S, Philpott MP ( 2016 ) . Stabilising the Glucocorticoid Response in Psoriatic Skin . vol. 175 , pp. 45 - 45 .
Chopra N, Yang K, Upton J, Abbasi QH, Qaraqe K, Philpott M, ALOMAINY AHM ( 2016 ) . Fibroblasts Cell Number Density based Human Skin Characterization at THz for In-body Nanonetworks . Elsevier Nano Communication Networks
Chopra N, Upton J, Philpott M, Alomainy A, Abbasi QH, Qaraqe K ( 2016 ) . Characterization of volumetric change in collagen using THz time domain spectroscopy for in-body nanonetworks . Proceedings of the 3rd ACM International Conference on Nanoscale Computing and Communication, ACM NANOCOM 2016 .
Figlak K, Paus R, Philpott M ( 2016 ) . 204 Towards dissecting the role of glycogen metabolism in human hair follicle biology . Journal of Investigative Dermatology . vol. 136 ,
Chopra N, Yang K, Abbasi QH, Qaraqe KA, Philpott M, Alomainy A ( 2016 ) . THz time-domain spectroscopy of human skin tissue for in-body nanonetworks . IEEE Transactions on Terahertz Science and Technology vol. PP , ( 99 )
Reddy SV, Philpott MP, Trigiante G ( 2016 ) . Retaining in-gel zymographic activity of cysteine proteases via a cysteine supplemented running buffer . Electrophoresis
Akinduro O, Sully K, Patel A, Robinson DJ, Chikh A, McPhail G, Braun KM, Philpott MP et al. ( 2016 ) . Constitutive Autophagy and Nucleophagy during Epidermal Differentiation . Journal of Investigative Dermatology vol. 136 , ( 7 ) 1460 - 1470 .
Chew EGY, Tan JHJ, Bahta AW, Ho BS-Y, Liu X, Lim TC, Sia YY, Bigliardi PL et al. ( 2016 ) . Differential expression between human dermal papilla cells from balding and non-balding scalps reveals new candidate genes for androgenetic alopecia . Journal of Investigative Dermatology
Yang K, Chopra N, Upton J, Hao Y, Philpott M, Alomainy A, Abbasi QH, Qaraqe K ( 2015 ) . Characterising skin-based nano-networks for healthcare monitoring applications at THz . IEEE Antennas and Propagation Society, AP-S International Symposium (Digest) . vol. 2015-October , 199 - 200 .
Hannen R, Udeh-Momoh C, Upton J, Sevilla L, Lightman S, Perez P, Philpott M ( 2015 ) . Beyond the Adrenal Gland: The Essential Role of Skin-Synthesised Glucocorticoids in Health and Disease . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 135 , S8 - S8 .
Upton JH, Hannen RF, Bahta AW, Farjo N, Farjo B, Philpott MP ( 2015 ) . Oxidative stress-associated senescence in dermal papilla cells of men with androgenetic alopecia . Journal of Investigative Dermatology vol. 135 , ( 5 ) 1244 - 1252 .
Moore M, Philpott M, Bishop C ( 2015 ) . 52PA siRNA screen to re-activate senescence in basal-like breast cancer . Annals of Oncology vol. 26 , ( suppl_3 ) iii18 - iii18 .
Chopra N, Yang K, Upton J, Alomainy A, Philpott M, Hao Y ( 2015 ) . Understanding and characterizing nanonetworks for healthcare monitoring applications . Conference Proceedings - 2014 IEEE MTT-S International Microwave Workshop Series on: RF and Wireless Technologies for Biomedical and Healthcare Applications, IMWS-Bio 2014 .
Chopra N, Yang K, Philpott M, Alomainy A, Abbasi QH, Qaraqe K ( 2015 ) . Characterization of human skin using Thz time domain spectroscopy for in-body nanonetworks . EAI International Conference on Bio-inspired Information and Communications Technologies (BICT) .
Langan EA, Philpott MP, Kloepper JE, Paus R ( 2015 ) . Human hair follicle organ culture: Theory, application and perspectiDes . Experimental Dermatology vol. 24 , ( 12 ) 200 - 215 .
Hannen R, Udeh C, Rajpopat S, Perez P, Philpott M ( 2014 ) . Deficiency of the local cortisol stress response pathway in psoriatic skin . BRITISH JOURNAL OF DERMATOLOGY . vol. 171 , E170 - E171 .
Chew EG, Hillmer AM, Tan JH, Philpott MP, Bahta AW ( 2014 ) . Androgenetic Alopecia: Analysis of transcriptome differences between balding and non-balding human dermal papilla cells . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 134 , S67 - S67 .
Bladen J, Thaung C, Beaconsfield M, O'Toole E, Philpott M ( 2014 ) . Analysis of the Hedgehog signalling pathway in periocular sebaceous gland carcinoma . INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE . vol. 55 ,
Al-Nuaimi Y, Hardman JA, Bíró T, Haslam IS, Philpott MP, Tóth BI, Farjo N, Farjo B et al. ( 2014 ) . A meeting of two chronobiological systems: circadian proteins Period1 and BMAL1 modulate the human hair cycle clock . J Invest Dermatol vol. 134 , ( 3 ) 610 - 619 .
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao X, Ikram M, Teh M-T et al. ( 2014 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . Cell Death Dis vol. 5 ,
Sully K, Akinduro O, Philpott MP, Naeem AS, Harwood CA, Reeve VE, O'Shaughnessy RF, Byrne C ( 2013 ) . The mTOR inhibitor rapamycin opposes carcinogenic changes to epidermal Akt1/PKBα isoform signaling . Oncogene vol. 32 , ( 27 ) 3254 - 3262 .
Harrison W, Cochrane B, Neill G, Philpott M ( 2013 ) . The oncogenic GLI transcription factors facilitate keratinocyte survival and transformation upon exposure to genotoxic agents . Oncogene
Al-Nuaimi Y, Hardman JA, Haslam IS, Biro T, Toth BI, Farjo N, Farjo B, Philpott M et al. ( 2013 ) . A meeting of two chronobiological systems: Period1 and BMAL1 modulate the human hair cycle . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , 1416 - 1416 .
Akinduro O, Sully K, Chikh A, O'shaughnessy RF, Bergamaschi D, Harwood CA, Philpott MP, Byrne C ( 2013 ) . Constitutive autophagy as a terminal differentiation mechanism . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S127 - S127 .
Pantazi E, Gemenetzidis E, Trigiante G, Warnes G, Shan L, Mao E, Ikram M, Neill G et al. ( 2013 ) . GLI2 induces genomic instability in human keratinocytes by inhibiting apoptosis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S57 - S57 .
Rahman M, Selway J, Herath D, Hazan A, Roy A, Langlands K, Edmunds S, Kelsell D et al. ( 2013 ) . Gene expression profiling demonstrates that the effects of PTCH1 suppression are not fully reversed upon pharmacological inhibition of SMOOTHENED in human keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S68 - S68 .
Hannen R, Nikitorowicz-Buniak J, Stratton R, Ahmed A, Rajpopat S, Philpott M ( 2013 ) . Loss of the local cortisol stress response pathway contributes to the pathogenesis inflammatory skin diseases . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S116 - S116 .
Drymoussi Z, Lemonas P, Myers S, Philpott MP, Navsaria H ( 2013 ) . Matrix metalloproteinases 1, 2, 13 and 14 are differentially expressed in keloid scars compared to normal skin . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S250 - S250 .
Upton JH, Bahta A, Farjo N, Farjo B, Bhogal R, Philpott MP ( 2013 ) . Oxidative stress and cell senescence in androgenetic alopecia (AGA) . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , 1398 - 1398 .
Robles V, Philpott M, Navsaria H ( 2013 ) . Tissue engineering a 3-D functional model of the human eccrine sweat gland . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 133 , S77 - S77 .
Brocklehurst K, Philpott MP ( 2013 ) . Cysteine proteases: mode of action and role in epidermal differentiation . Cell Tissue Res vol. 351 , ( 2 ) 237 - 244 .
Philpott MP ( 2012 ) . Hair follicle culture .
Patel II, Harrison WJ, Kerns JG, Filik J, Wehbe K, Carmichael PL, Scott AD, Philpott MP et al. ( 2012 ) . Isolating stem cells in the inter-follicular epidermis employing synchrotron radiation-based Fourier-transform infrared microspectroscopy and focal plane array imaging . ANALYTICAL AND BIOANALYTICAL CHEMISTRY vol. 404 , ( 6-7 ) 1745 - 1758 .
Hannen R, Rajpopat S, Cerio R, Burrin J, Philpott M ( 2012 ) . Downregulation of the Intracrine Skin Glucocorticoid Pathway in Psoriasis . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 132 , S53 - S53 .
Herath D, Rahman M, Mancuso M, Panagou L, Atkar R, Pirzado M, Saran A, Harwood C et al. ( 2012 ) . Epidermal growth factor receptor signalling in basal cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 166 , e24 - e24 .
Rahman M, Herath D, Selway J, Roy A, Nadendla S, Kelsell D, Harwood C, Philpott M et al. ( 2012 ) . In vitro modelling of basal cell carcinoma reveals a novel PTCH1-GLI1 signalling axis that is unresponsive to Smoothened inhibitors in human keratinocytes . BRITISH JOURNAL OF DERMATOLOGY . vol. 166 , e29 - e29 .
Chikh A, Matin RNH, Senatore V, Hufbauer M, Lavery D, Raimondi C, Ostano P, Mello-Grand M et al. ( 2011 ) . iASPP/p63 autoregulatory feedback loop is required for the homeostasis of stratified epithelia . EMBO J vol. 30 , ( 20 ) 4261 - 4273 .
Ramot Y, Tiede S, Biro T, Abu Bakar MH, Sugawara K, Philpott MP, Harrison W, Pietila M et al. ( 2011 ) . Spermidine Promotes Human Hair Growth and Is a Novel Modulator of Human Epithelial Stem Cell Functions . PLOS ONE vol. 6 , ( 7 ) Article e22564 ,
Rahman MM, Kelsell DP, Philpott MP, Neill GW ( 2011 ) . In vitro modelling of basal cell carcinoma reveals a novel PTCH1-GLI1 signalling axis that is independent of SMOOTHENED in human keratinocytes . BRITISH JOURNAL OF DERMATOLOGY . vol. 164 , 907 - 908 .
Pirzado MS, Rahman MM, Cerio R, Neill GW, Philpott MP ( 2011 ) . Senescence in human basal cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 164 , 935 - 936 .
Herath D, Rahman MM, Panagou L, Pirzado M, Harwood C, Philpott MP, Neill GW ( 2011 ) . The tumour suppressor PTCH1 regulates EGFR signalling in human keratinocytes: implications for the treatment of basal cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 164 , 934 - 934 .
Ruge F, Glavini A, Gallimore AM, Richards HE, Thomas CP, O'Donnell VB, Philpott MP, Porter RM ( 2011 ) . Delineating Immune-Mediated Mechanisms Underlying Hair Follicle Destruction in the Mouse Mutant Defolliculated . J INVEST DERMATOL vol. 131 , ( 3 ) 572 - 579 .
Hannen RF, Michael AE, Jaulim A, Bhogal R, Burrin JM, Philpott MP ( 2011 ) . Steroid synthesis by primary human keratinocytes; implications for skin disease . Biochem Biophys Res Commun vol. 404 , ( 1 ) 62 - 67 .
Nadendla SK, Hazan A, Ward M, Harper LJ, Moutasim K, Bianchi LS, Naase M, Ghali L et al. ( 2011 ) . GLI1 confers profound phenotypic changes upon LNCaP prostate cancer cells that include the acquisition of a hormone independent state . PLoS One vol. 6 , ( 5 )
Sully K, Akinduro OA, Philpott MP, Harwood CA, O'Shaughnessy RF, Byrne C ( 2011 ) . Rapamycin treatment increases mTORC2 activity and selectively activates the AKT1 isoform in epidermis by inhibition of the mTORC1-dependent feedback loop to IRS-1 . MOLECULAR BIOLOGY OF THE CELL . vol. 22 ,
Bahta AW, Farjo N, Farjo B, Philpott MP ( 2010 ) . Expression of p16INK4 alpha in balding scalp hair follicles suggests an increased susceptibility to premature senescence and a possible mechanism of androgenetic alopecia Hormones, Hair Growth and Pattern Hair Loss . EXPERIMENTAL DERMATOLOGY . vol. 19 , 571 - 571 .
Upton JH, Bahta A, Farjo N, Farjo B, Philpott MP ( 2010 ) . Senescence of male balding dermal papilla cells is associated with oxidative stress Hormones, Hair Growth and Pattern Hair Loss . EXPERIMENTAL DERMATOLOGY . vol. 19 , 570 - 570 .
Pantazi E, Trigiante G, Warnes G, Gemenetzidis E, Teh MT, Ikram M, Shan L, Lu YJ et al. ( 2010 ) . Overexpression of GLI2 in human keratinocytes results in resistance to ultraviolet B-induced apoptosis and increased chromosomal instability . BRITISH JOURNAL OF DERMATOLOGY . vol. 162 , 948 - 948 .
Singh M, Breuer J, Heseltine R, Cerio R, Millar J, Philpott MP, O'Toole EA ( 2010 ) . Varicella-zoster replication and its association with keratin 15 expression and Wnt signalling . BRITISH JOURNAL OF DERMATOLOGY . vol. 162 , 914 - 915 .
Teh M-T, Gemenetzidis E, Chaplin T, Young BD, Philpott MP ( 2010 ) . Upregulation of FOXM1 induces genomic instability in human epidermal keratinocytes . Mol Cancer vol. 9 ,
Al-Nuaimi Y, Kloepper JE, Philpott M, Toth BI, Watson RE, Gaspar E, Tiede S, Biro T et al. ( 2010 ) . Two chronobiological systems meet: Genes, proteins and microRNAs central to circadian rhythm control are differentially regulated during cyclic human hair follicle cycling . EXPERIMENTAL DERMATOLOGY . vol. 19 , 216 - 216 .
Al-Nuaimi Y, Philpott M, Kloepper J, Toth B, McKay I, Biro T, Paus R ( 2009 ) . A role for clock-related genes in human hair growth control? . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 129 , S67 - S67 .
Gore SM, Kasper M, Williams T, Regl G, Aberger F, Cerio R, Neill GW, Philpott MP ( 2009 ) . Neuronal differentiation in basal cell carcinoma: possible relationship to Hedgehog pathway activation? . J Pathol vol. 219 , ( 1 ) 61 - 68 .
Bianchi L, Philpott MP, Neill W ( 2009 ) . A potential paracrine mode of hedgehog signalling in basal cell carcinoma development . BRITISH JOURNAL OF DERMATOLOGY . vol. 160 , 926 - 927 .
Elliott JA, Navsaria H, Philpott MP ( 2009 ) . Modelling of basal cell carcinoma: culture and investigation of basal cell carcinoma-derived fibroblasts . BRITISH JOURNAL OF DERMATOLOGY . vol. 160 , 926 - 926 .
Ruge F, Glavini A, Philpott MP, Porter RM ( 2009 ) . Mutations in gasdermin suggest paracrine control of PPAR gamma is responsible for maintaining sebaceous gland differentiation . BRITISH JOURNAL OF DERMATOLOGY . vol. 160 , 922 - 923 .
Pantazi E, Trigianti G, Warnes G, Gemenetzidis E, Teh MT, Philpott MP ( 2009 ) . Overexpression of GLI2 in human keratinocytes results in polyploidy and resistance to ultraviolet B-induced apoptosis . BRITISH JOURNAL OF DERMATOLOGY . vol. 160 , 908 - 908 .
Singh M, Breuer J, Heseltine R, Millar J, Philpott MP, O'Toole EA ( 2009 ) . Varicella-zoster virus infection in skin shows prominent involvement of adnexal stem cell compartments . BRITISH JOURNAL OF DERMATOLOGY . vol. 160 , 904 - 904 .
Roosen GF, Westgate GE, Philpott M, Berretty PJM, Nuijs T ( 2008 ) . Temporary hair removal by low fluence photoepilation: Histological study on biopsies and cultured human hair follicles . LASER SURG MED vol. 40 , ( 8 ) 520 - 528 .
Bahta AW, Farjo N, Farjo B, Philpott MP ( 2008 ) . Premature senescence of balding dermal papilla cells in vitro is associated with p16(INK4a) expression . J Invest Dermatol vol. 128 , ( 5 ) 1088 - 1094 .
Hannen RF, Michael AE, Burrin J, Philpott M ( 2008 ) . Cortisol synthesis and regulation of proliferation in keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 128 , S139 - S139 .
Bahta AW, Farjo N, Farjo B, Philpott MP ( 2008 ) . Effect of oxygen on premature senescence of balding dermal papilla cells in vitro identifies oxidative stress as a potential mechanism of androgenetic alopecia . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 128 , S149 - S149 .
Williams TD, Ikram MS, Harrison WJ, Bianchi LS, Philpott MP, Neill GW ( 2008 ) . GLI1 induces characteristics of a senescent response in N/Tert-1 keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 128 , S33 - S33 .
Neill GW, Harrison WJ, Ikram MS, Williams TDL, Bianchi LS, Nadendla SK, Green JL, Ghali L et al. ( 2008 ) . GLI1 repression of ERK activity correlates with colony formation and impaired migration in human epidermal keratinocytes . Carcinogenesis vol. 29 , ( 4 ) 738 - 746 .
Neill GW, Harrison W, Ikram M, Williams T, Bianchi L, Nadendla S, O'Toole EA, Aberger F et al. ( 2008 ) . GLI1 repression of epidermal growth factor receptor extracellular signal-regulated kinase signalling may account for the poor metastatic potential of basal cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 158 , 884 - 884 .
Singh M, Breuer J, Cerio R, Millar J, Philpott MP, O'Toole EA ( 2008 ) . Immunohistochemical study of varicella-zoster virus infection in skin confirms prominent involvement of the follicular epithelium . BRITISH JOURNAL OF DERMATOLOGY . vol. 158 , 892 - 892 .
Russell LE, Tropel P, Philpott MP, Navsaria H ( 2008 ) . Mesenchymal control on keratinocyte phenotype . BRITISH JOURNAL OF DERMATOLOGY . vol. 158 , 903 - 903 .
Bahta AW, Farjo N, Farjo B, Philpott MP ( 2008 ) . Premature senescence of balding dermal papilla cells in vitro is associated with p16(INK4a) expression and identifies environmental stress as a potential mechanism of androgenetic alopecia . BRITISH JOURNAL OF DERMATOLOGY . vol. 158 , 880 - 880 .
Hannen RF, Michael AE, Burrin J, Philpott MP ( 2008 ) . StAR role for glucocorticoid synthesis in keratinocytes . BRITISH JOURNAL OF DERMATOLOGY . vol. 158 , 881 - 881 .
Singh M, Breuer J, Cerio R, Millar J, Philpott MP, O'Toole EA ( 2008 ) . Varicella zoster virus colocalizes within adnexal stem cell compartments of skin . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 128 , S194 - S194 .
Kloepper JE, Hendrix S, Bodó E, Tiede S, Humphries MJ, Philpott MP, Fässler R, Paus R ( 2008 ) . Functional role of beta 1 integrin-mediated signalling in the human hair follicle . Exp Cell Res vol. 314 , ( 3 ) 498 - 508 .
Neill W, Harrison WJ, Ikram MS, Williams TDL, Green JL, Ghali L, Frischauf AM, O'Toole EA et al. ( 2007 ) . Attenuation of EGFR-ERK signalling by GLI1 highlights a mechanism to promote the epithelial phenotype and may account for the poor metastatic potential of basal cell carcinoma . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 127 , S91 - S91 .
Russell LE, Harrison WJ, Bahta AW, Zouboulis CC, Burrin JM, Philpott MP ( 2007 ) . Characterization of liver X receptor expression and function in human skin and the pilosebaceous unit . Exp Dermatol vol. 16 , ( 10 ) 844 - 852 .
Hannen RF, Michael AE, Burrin JM, Philpott M ( 2007 ) . Human skin and keratinocytes express cholesterol transporters and primary keratinocytes are capable of metabolising progesterone into cortisol . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 127 , S60 - S60 .
Williams TDL, Harrison WJ, Ikram MS, Philpott M, Neill W ( 2007 ) . The oncogenic GLI (GLI1 and GLI2) transcription factors induce characteristics of cellular senescence in N/Tert-1 keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 127 , S92 - S92 .
Harrison WJ, Bull JJ, Seltmann H, Zouboulis CC, Philpott MP ( 2007 ) . Expression of lipogenic factors galectin-12, resistin, SREBP-1, and SCD in human sebaceous glands and cultured sebocytes . J Invest Dermatol vol. 127 , ( 6 ) 1309 - 1317 .
Blaydon DC, Philpott MP, Kelsell DP ( 2007 ) . R-spondins in cutaneous biology: Nails and cancer . Cell Cycle vol. 6 , ( 8 ) 895 - 897 .
Blaydon DC, Philpott MP, Kelsell DP ( 2007 ) . R-spondins in cutaneous biology: nails and cancer . Cell Cycle vol. 6 , ( 8 ) 895 - 897 .
Teh MT, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM et al. ( 2007 ) . Erratum: Role for WNT16B in human epidermal keratinocyte proliferation and differentiation (Journal of Cell Science vol. 120 (330-339)) . Journal of Cell Science vol. 120 , ( 5 )
Teh MT, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM et al. ( 2007 ) . Role for WNT16B in human epidermal keratinocyte proliferation and differentiation (vol 120, pg 330, 2007) . J CELL SCI vol. 120 , ( 5 ) 917 - 917 .
Teh M-T, Blaydon D, Ghali LR, Briggs V, Edmunds S, Pantazi E, Barnes MR, Leigh IM et al. ( 2007 ) . Role for WNT16B in human epidermal keratinocyte proliferation and differentiation . J Cell Sci vol. 120 , ( Pt 2 ) 330 - 339 .
Philpott MP ( 2007 ) . Antimicrobial peptides and acne . Acne and its Therapy ,
Gore S, Kasper M, Frischauf A, Aberger F, Grover R, Cerio R, Neill G, Philpott M ( 2006 ) . In vitro modelling of basal cell carcinoma . Journal of Plastic Reconstructive & Aesthetic Surgery vol. 59 , ( 9 ) s1 - s2 .
Kasper M, Schnidar H, Neill GW, Hanneder M, Klingler S, Blaas L, Schmid C, Hauser-Kronberger C et al. ( 2006 ) . Selective modulation of Hedgehog/GLI target gene expression by epidermal growth factor signaling in human keratinocytes . Mol Cell Biol vol. 26 , ( 16 ) 6283 - 6298 .
Williams T, Trigiante G, Philpott MP, Neill GW ( 2006 ) . Overexpression of the GLI oncoproteins induces characteristics of a senescent phenotype in keratinocytes . BRITISH JOURNAL OF DERMATOLOGY . vol. 155 , 243 - 243 .
Bahta A, Bull J, Farjo B, Farjo N, Philpott M ( 2006 ) . Senescence in cultured primary balding and non-balding dermal papilla cells their immortalisation and characterisation . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 126 , 97 - 97 .
Teh M-T, Blaydon D, Chaplin T, Foot NJ, Skoulakis S, Raghavan M, Harwood CA, Proby CM et al. ( 2005 ) . Genomewide single nucleotide polymorphism microarray mapping in basal cell carcinomas unveils uniparental disomy as a key somatic event . Cancer Res vol. 65 , ( 19 ) 8597 - 8603 .
Gore S, Williams T, Grover R, Abeger F, Frischauf A, Kasper M, Neill G, Cerio R et al. ( 2005 ) . Neuronal differentiation in basal cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 153 , 64 - 64 .
Bull JJ, Pelengaris S, Hendrix S, Chronnell CMT, Khan M, Philpott MP ( 2005 ) . Ectopic expression of c-Myc in the skin affects the hair growth cycle and causes an enlargement of the sebaceous gland . Br J Dermatol vol. 152 , ( 6 ) 1125 - 1133 .
Teh M, Quinn AG, Philpott MP ( 2005 ) . FOXM1b activates DNA repair and suppresses UVB-induced apoptosis in human keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 124 , A17 - A17 .
Blaydon DC, Teh M, Foot NJ, Philpott MP, Harwood C, Proby C, Young BD, Kelsell DP ( 2005 ) . Genome-wide SNP microarray mapping in basal cell carcinomas unveils uniparental dismay as a key somatic event . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 124 , A20 - A20 .
Neill GW, Kasper M, Williams T, Ikram M, Ghali L, Green J, Quinn A, Frischauf A et al. ( 2005 ) . Gli1 co-operates with EGFR signalling to induce a neuronal phenotype in keratinocytes . BRITISH JOURNAL OF DERMATOLOGY . vol. 152 , 844 - 844 .
Gore S, Kasper M, Williams T, Frischauf A, Aberger F, Grover R, Cerio R, Neill G et al. ( 2005 ) . Novel in vitro modelling of basal cell carcinoma . BRITISH JOURNAL OF DERMATOLOGY . vol. 152 , 856 - 856 .
Teh MT, Quinn AG, Philpott MP ( 2005 ) . The Human forkhead transcription factor FOXM1B enhances DNA repair and suppresses UVB-induced apoptosis . BRITISH JOURNAL OF DERMATOLOGY . vol. 152 , 842 - 843 .
Harrison WJ, Bull JJ, Zouboulis CC, Philpott MP ( 2005 ) . The expression of early markers of adipocyte differentiation in sebaceous gland cells . BRITISH JOURNAL OF DERMATOLOGY . vol. 152 , 856 - 856 .
Philpott M ( 2005 ) . What is the pathogenesis of acne? Commentary 1 . EXP DERMATOL vol. 14 , ( 2 ) 150 - 150 .
Zouboulis CC, Eady EA, Philpott MP, Goldsmith LA, Orfanos CE, Cunliffe BWC, Rosenfield RL ( 2005 ) . What is the pathogenesis of acne? . Experimental Dermatology vol. 14 , ( 2 )
Regl G, Kasper M, Schnidar H, Eichberger T, Neill GW, Philpott MP, Esterbauer H, Hauser-Kronberger C et al. ( 2004 ) . Activation of the BCL2 promoter in response to Hedgehog/GLI signal transduction is predominantly mediated by GLI2 . Cancer Res vol. 64 , ( 21 ) 7724 - 7731 .
Ikram MS, Neill GW, Regl G, Eichberger T, Frischauf A-M, Aberger F, Quinn A, Philpott M ( 2004 ) . GLI2 is expressed in normal human epidermis and BCC and induces GLI1 expression by binding to its promoter . J Invest Dermatol vol. 122 , ( 6 ) 1503 - 1509 .
Eichberger T, Regl G, Ikram MS, Neill GW, Philpott MP, Aberger F, Frischauf A-M ( 2004 ) . FOXE1, a new transcriptional target of GLI2 is expressed in human epidermis and basal cell carcinoma . J Invest Dermatol vol. 122 , ( 5 ) 1180 - 1187 .
Neill G, Ikram MS, Green JL, Quinn AG, O'Toole E, Philpott MP ( 2004 ) . Gli1 co-operates with EGFR-Sre signalling to induce a fibroblastoid phenotype in primary keratinocytes . JOURNAL OF INVESTIGATIVE DERMATOLOGY . vol. 122 , A17 - A17 .
Regl G, Kasper M, Schnidar H, Eichberger T, Neill GW, Ikram MS, Quinn AG, Philpott MP et al. ( 2004 ) . The zinc-finger transcription factor GLI2 antagonizes contact inhibition and differentiation of human epidermal cells . Oncogene vol. 23 , ( 6 ) 1263 - 1274 .
Ghali L, Wong S-T, Tidman N, Quinn A, Philpott MP, Leigh IM ( 2004 ) . Epidermal and hair follicle progenitor cells express melanoma-associated chondroitin sulfate proteoglycan core protein . J Invest Dermatol vol. 122 , ( 2 ) 433 - 442 .
Philpott MP ( 2003 ) . Defensins and acne . Mol Immunol vol. 40 , ( 7 ) 457 - 462 .
Neill GW, Ghali LR, Green JL, Ikram MS, Philpott MP, Quinn AG ( 2003 ) . Loss of protein kinase Calpha expression may enhance the tumorigenic potential of Gli1 in basal cell carcinoma . Cancer Res vol. 63 , ( 15 ) 4692 - 4697 .
Randall VA, Sundberg JP, Philpott MP ( 2003 ) . Animal and in vitro models for the study of hair follicles . J Investig Dermatol Symp Proc . vol. 8 , 39 - 45 .
Müller FB, Müller-Röver S, Korge BP, Kapas S, Hinson JP, Philpott MP ( 2003 ) . Adrenomedullin: expression and possible role in human skin and hair growth . Br J Dermatol vol. 148 , ( 1 ) 30 - 38 .
Teh M-T, Wong S-T, Neill GW, Ghali LR, Philpott MP, Quinn AG ( 2002 ) . FOXM1 is a downstream target of Gli1 in basal cell carcinomas . Cancer Res vol. 62 , ( 16 ) 4773 - 4780 .
Neill GW, Green JL, Philpott MP, Quinn AG ( 2002 ) . Differential regulation of Gli1 activity by PKC isoforms . J INVEST DERMATOL vol. 119 , ( 1 ) 276 - 276 .
Bull JJ, Müller-Röver S, Chronnell CMT, Paus R, Philpott MP, McKay IA ( 2002 ) . Contrasting expression patterns of CCAAT/enhancer-binding protein transcription factors in the hair follicle and at different stages of the hair growth cycle . J Invest Dermatol vol. 118 , ( 1 ) 17 - 24 .
Chronnell CM, Ghali LR, Ali RS, Quinn AG, Holland DB, Bull JJ, Cunliffe WJ, McKay IA et al. ( 2001 ) . Human beta defensin-1 and -2 expression in human pilosebaceous units: upregulation in acne vulgaris lesions . J Invest Dermatol vol. 117 , ( 5 ) 1120 - 1125 .
Fletcher ST, Fentem JH, Basketter DA, Kelsell DP, Philpott M, Baker VA ( 2001 ) . Microarray and proteomic analysis of early gene regulation following exposure to skin irritants . TOXICOLOGY vol. 168 , ( 1 ) 101 - 102 .
Mueller-Roever S, Beckley C, Philpott M, Paus R ( 2001 ) . Integrin expression is hair cycle-dependent, and integrin blockers stimulate human hair growth in vitro . J INVEST DERMATOL vol. 117 , ( 2 ) 396 - 396 .
Bull JJ, Müller-Röver S, Patel SV, Chronnell CM, McKay IA, Philpott MP ( 2001 ) . Contrasting localization of c-Myc with other Myc superfamily transcription factors in the human hair follicle and during the hair growth cycle . J Invest Dermatol vol. 116 , ( 4 ) 617 - 622 .
Chronnell CMT, Ghali LR, Ali RS, Quinn AG, Holland DB, Bull JJ, Cunliffe WJ, McKay IA et al. ( 2001 ) . Human β defensin-1 and -2 expression in human pilosebaceous units: Upregulation in acne vulgaris lesions . Journal of Investigative Dermatology vol. 117 , ( 5 ) 1120 - 1125 .
Philpott MP, Kealey T ( 2000 ) . Cyclical changes in rat vibrissa follicles maintained in vitro . J INVEST DERMATOL vol. 115 , ( 6 ) 1152 - 1155 .
Philpott M ( 1999 ) . In vitro maintenance of isolated hair follicles: Current status and future development . Experimental Dermatology . vol. 8 , 317 - 319 .
Westgate GE, Tidman N, De Berker D, Blount MA, Philpott MP, Leigh IM ( 1997 ) . Characterization of LHTric-1, a new monospecific monoclonal antibody to the trichocyte keratin Ha1 . British Journal of Dermatology vol. 137 , ( 1 ) 24 - 30 .
Kealey T, Philpott M, Guy R ( 1997 ) . Human pilosebaceous culture . Methods in molecular biology (Clifton, N.J.) vol. 75 , 101 - 115 .
Kealey T, Philpott M, Guy R ( 1997 ) . The regulatory biology of the human pilosebaceous unit . Bailliere's Clinical Obstetrics and Gynaecology vol. 11 , ( 2 ) 205 - 227 .
Rudman SM, Philpott MP, Thomas GA, Kealey T ( 1997 ) . The role of IGF-I in human skin and its appendages: Morphogen as well as mitogen? . Journal of Investigative Dermatology vol. 109 , ( 6 ) 770 - 777 .
Philpott MP, Sanders DA, Bowen J, Kealey T ( 1996 ) . Effects of interleukins, colony-stimulating factor and tumour necrosis factor on human hair follicle growth in vitro: A possible role for interleukin-1 and tumour necrosis factor-α in alopecia areata . British Journal of Dermatology vol. 135 , ( 6 ) 942 - 948 .
Sanders DA, Fiddes I, Thompson DM, Philpott MP, Westgate GE, Kealey T ( 1996 ) . In the absence of streptomycin, minoxidil potentiates the mitogenic effects of fetal calf serum, insulin-like growth factor 1, and platelet-derived growth factor on NIH 3T3 fibroblasts in a K<sup>+</sup> channel-dependent fashion . Journal of Investigative Dermatology vol. 107 , ( 2 ) 229 - 234 .
Philpott MP, Sanders DA, Kealey T ( 1996 ) . Whole hair follicle culture . Dermatologic Clinics vol. 14 , ( 4 ) 595 - 607 .
Philpott MP, Sanders D, Kealey T ( 1995 ) . Cultured human hair follicles and growth factors . Journal of Investigative Dermatology . vol. 104 , 44 - 45 .
Philpott MP, Kealey T ( 1994 ) . Effects of EGF on the morphology and patterns of DNA synthesis in isolated human hair follicles . Journal of Investigative Dermatology vol. 102 , ( 2 ) 186 - 191 .
Philpott MP, Sanders DA, Kealey T ( 1994 ) . Effects of insulin and insulin-like growth factors on cultured human hair follicles: IGF-I at physiologic concentrations is an important regulator of hair follicle growth in vitro . Journal of Investigative Dermatology vol. 102 , ( 6 ) 857 - 861 .
Philpott MP, Sanders D, Westgate GE, Kealey T ( 1994 ) . Human hair growth in vitro: a model for the study of hair follicle biology . Journal of Dermatological Science vol. 7 , ( SUPPL. 1 )
Kealey T, Williams R, Philpott MP ( 1994 ) . The human hair follicle engages in glutaminolysis and aerobic glycolysis: Implications for skin, splanchnic and neoplastic metabolism . Skin Pharmacology and Physiology vol. 7 , ( 1-2 ) 41 - 46 .
SANDERS DA, PHILPOTT MP, NICOLLE FV, KEALEY T ( 1994 ) . The isolation and maintenance of the human pilosebaceous unit . British Journal of Dermatology vol. 131 , ( 2 ) 166 - 176 .
Williams R, Philpott MP, Kealey T ( 1993 ) . Metabolism of freshly isolated human hair follicles capable of hair elongation: A glutaminolytic, aerobic glycolytic tissue . Journal of Investigative Dermatology vol. 100 , ( 6 ) 834 - 840 .
Westgate GE, Gibson WT, Kealey T, Philpott MP ( 1993 ) . Prolonged maintenance of human hair follicles in vitro in a serum-free medium . British Journal of Dermatology vol. 129 , ( 4 ) 372 - 379 .
Philpott MP, Green MR, Kealey T ( 1992 ) . Rat hair follicle growth in vitro . British Journal of Dermatology vol. 127 , ( 6 ) 600 - 607 .
PHILPOTT MP, WESTGATE GE, KEALEY T ( 1991 ) . An in Vitro Model for the Study of Human Hair Growth . Annals of the New York Academy of Sciences vol. 642 , ( 1 ) 148 - 164 .
KEALEY T, WILLIAMS R, PHILPOTT MP ( 1991 ) . Intermediary Metabolism of the Human Hair Follicle . Annals of the New York Academy of Sciences vol. 642 , ( 1 ) 301 - 307 .
Philpott MP, Green MR, Kealey T ( 1990 ) . Human hair growth in vitro . Journal of Cell Science vol. 97 , ( 3 ) 463 - 471 .
Philpott MP, Kealey T ( 1990 ) . Metabolic studies on isolated hair follicles: Hair follicles engage in aerobic glycolysis and do not demonstrate the glucose fatty acid cycle . Journal of Investigative Dermatology vol. 96 , ( 6 ) 875 - 879 .
Barth JH, Ridden J, Philpott MP, Greenall MJ, Kealey T ( 1989 ) . Lipogenesis by isolated human apocrine sweat gland: Testosterone has no effect during long-term organ maintenance . Journal of Investigative Dermatology vol. 92 , ( 3 ) 333 - 336 .
Philpott M, Green MR, Kealey T ( 1989 ) . Studies on the biochemistry and morphology of freshly isolated and maintained rat hair follicles . Journal of Cell Science vol. 93 , ( 3 ) 409 - 418 .