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Research

Publications: Mrs Tatiana Novoselova

Romano LEL, Aw WY, Hixson KM, Novoselova TV, Havener TM, Howell S, Taylor-Blake B, Hall CL et al. ( 2022 ) . Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization . Cell Reports vol. 41 , ( 5 )
Sladen PE, Jovanovic K, Guarascio R, Ottaviani D, Salsbury G, Novoselova T, Chapple JP, Yu-Wai-Man P et al. ( 2022 ) . Modelling autosomal dominant optic atrophy associated with OPA1 variants in iPSC-derived retinal ganglion cells . Human Molecular Genetics vol. 31 , ( 20 ) 3478 - 3493 .
Sladen PE, Perdigão PRL, Salsbury G, Novoselova T, van der Spuy J, Chapple JP, Yu-Wai-Man P, Cheetham ME ( 2021 ) . CRISPR-Cas9 correction of OPA1 c.1334G>A: p.R445H restores mitochondrial homeostasis in dominant optic atrophy patient-derived iPSCs . Molecular Therapy - Nucleic Acids vol. 26 , 432 - 443 .
Novoselova TV, King PJ, Guasti L, Metherell LA, Clark AJL, Chan LF ( 2019 ) . ACTH signalling and adrenal development: lessons from mouse models . Endocrine Connections vol. -1 , ( aop ) r122 - r130 .
Maharaj A, Maudhoo A, Chan LF, Novoselova T, Prasad R, Metherell LA, Guasti L ( 2019 ) . Isolated glucocorticoid deficiency: Genetic causes and animal models . Journal of Steroid Biochemistry and Molecular Biology vol. 189 , 73 - 80 .
CHAPPLE JP, O'TOOLE S, WATSON D, NOVOSELOVA T, ROMANO L, KING PJ, BRADSHAW T, THOMPSON CL et al. ( 2019 ) . Oncometabolite induced primary cilia loss in pheochromocytoma . Endocrine-Related Cancer
Novoselova TV, Hussain M, King PJ, Guasti L, Metherell LA, Charalambous M, Clark AJL, Chan LF ( 2018 ) . MRAP deficiency impairs adrenal progenitor cell differentiation and gland zonation . The FASEB Journal vol. 32 , ( 11 ) 6186 - 6196 .
Novoselova TV, Chan LF, Clark AJL ( 2018 ) . Pathophysiology of melanocortin receptors and their accessory proteins . Best Pract Res Clin Endocrinol Metab vol. 32 , ( 2 ) 93 - 106 .
CHAN L ( 2016 ) . A central role for melanocortin-4 receptors in offspring hypertension arising from maternal obesity . Proceedings of the National Academy of Sciences of USA
Novoselova TV, Larder R, Rimmington D, Lelliott C, Wynn E, Gorrigan RJ, Tate P, Guasti L et al. ( 2016 ) . Loss of Mrap2 is associated with Sim 1 deficiency and increased circulating cholesterol . Journal of EndocrinologyJOE-16-0057 - JOE-16-0057 .
Chan LF, Campbell DC, Novoselova TV, Clark AJL, Metherell LA ( 2015 ) . Whole-Exome Sequencing in the Differential Diagnosis of Primary Adrenal Insufficiency in Children . Frontiers in Endocrinology vol. 6 ,
Novoselova TV, Rath SR, Carpenter K, Pachter N, Dickinson JE, Price G, Chan LF, Choong CS et al. ( 2015 ) . NNT Pseudoexon Activation as a Novel Mechanism for Disease in Two Siblings With Familial Glucocorticoid Deficiency . JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM vol. 100 , ( 2 ) E350 - E354 .
Novoselova T, Larder R, Rimmington D, Lelliott C, Wynn E, O'Rahilly S, Clark A, Logan D et al. ( 2014 ) . Melanocortin 2 receptor accessory protein 2 (Mrap2) regulates hypothalamic melanocortin-4-receptor trafficking in vivo . Endocrine Abstracts
Novoselova T, Spoudeas H, Huebner A, Cheetham T, Chan L, Metherell L ( 2014 ) . Varied clinical presentations of six patients with mutations in CYP11A1 encoding the cholesterol side-chain cleavage enzyme, P450scc . Endocrine Abstracts
Chan L, Novoselova T, Rath S, Carpenter K, Pachter N, Price G, Dickinson J, Choong C et al. ( 2014 ) . cDNA analysis reveals NNT pseudoexon activation in two siblings with familial glucocorticoid deficiency . Endocrine Abstracts
Asai M, Ramachandrappa S, Joachim M, Shen Y, Zhang R, Nuthalapati N, Ramanathan V, Strochlic DE et al. ( 2013 ) . Loss of function of the melanocortin 2 receptor accessory protein 2 is associated with mammalian obesity . Science vol. 341 , ( 6143 ) 275 - 278 .
Novoselova TV, Rose R-S, Marks HM, Sullivan JA ( 2013 ) . SUMOylation regulates the homologous to E6-AP carboxyl terminus (HECT) ubiquitin ligase Rsp5p . J Biol Chem vol. 288 , ( 15 ) 10308 - 10317 .
Novoselova TV, Jackson D, Campbell DC, Clark AJL, Chan LF ( 2013 ) . Melanocortin receptor accessory proteins in adrenal gland physiology and beyond . J Endocrinol vol. 217 , ( 1 ) R1 - 11 .
Novoselova TV, Zahira K, Rose R-S, Sullivan JA ( 2012 ) . Bul proteins, a nonredundant, antagonistic family of ubiquitin ligase regulatory proteins . Eukaryot Cell vol. 11 , ( 4 ) 463 - 470 .
Schwarz N, Novoselova TV, Wait R, Hardcastle AJ, Cheetham ME ( 2012 ) . The X-linked retinitis pigmentosa protein RP2 facilitates G protein traffic . Hum Mol Genet vol. 21 , ( 4 ) 863 - 873 .
Novoselova EG, Glushkova OV, Cherenkov DA, Parfenyuk SB, Novoselova TV, Lunin SM, Khrenov MO, Guzhova IV et al. ( 2006 ) . Production of heat shock proteins, cytokines, and nitric oxide in toxic stress . BIOCHEMISTRY-MOSCOW+ vol. 71 , ( 4 ) 376 - 383 .
Novoselova TV, Margulis BA, Novoselov SS, Sapozhnikov AM, van der Spuy J, Cheetham ME, Guzhova IV ( 2005 ) . Treatment with extracellular HSP70/HSC70 protein can reduce polyglutamine toxicity and aggregation . J Neurochem vol. 94 , ( 3 ) 597 - 606 .
Novoselov SS, Novoselova TV, Verbova MV, Margulis BA, Guzhova IV ( 2005 ) . [The balance between Hsp70 and its cochaperones Hdj1 and Bag1 determines its substrate-binding activity] . Tsitologiia vol. 47 , ( 3 ) 220 - 229 .
Novoselov SS, Novoselova TV, Moskaleva OS, Margulis BA, Guzhova IV ( 2004 ) . [Dynamics of chaperone complex Hdj1-Hsp70-Bag1 as a response of erythroleukemia K562 cells to heat stress] . Tsitologiia vol. 46 , ( 7 ) 620 - 627 .