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Research

Publications: Prof Adrian Martineau

Talaei M, Faustini S, Holt H, Jolliffe DA, Vivaldi G, Greenig M, Perdek N, Maltby S et al. ( 2022 ) . Determinants of pre-vaccination antibody responses to SARS-CoV-2: a population-based longitudinal study (COVIDENCE UK) . BMC Medicine vol. 20 , ( 1 )
Dzavakwa NV, Chisenga M, McHugh G, Filteau S, Gregson CL, Kasonka L, Kranzer K, Mabuda HB et al. ( 2022 ) . Vitamin D<inf>3</inf> and calcium carbonate supplementation for adolescents with HIV to reduce musculoskeletal morbidity and immunopathology (VITALITY trial): study protocol for a randomised placebo-controlled trial . Trials vol. 23 , ( 1 )
Martineau AR ( 2022 ) . Vitamin D in the prevention or treatment of COVID-19 . Proc Nutr Soc1 - 18 .
Marshall BG, Keyvani P, Martineau AR ( 2022 ) . A rare infective cause for recurrent exacerbations and poor asthma control - Mycobacterium kumamotonense . JRSM Open vol. 13 , ( 10 )
Holt H, Relton C, Talaei M, Symons J, Davies MR, Jolliffe DA, Vivaldi G, Tydeman F et al. ( 2022 ) . Cohort Profile: Longitudinal population-based study of COVID-19 in UK adults (COVIDENCE UK) . Int J Epidemiol
Jolliffe DA, Faustini SE, Holt H, Perdek N, Maltby S, Talaei M, Greenig M, Vivaldi G et al. ( 2022 ) . Determinants of Antibody Responses to SARS-CoV-2 Vaccines: Population-Based Longitudinal Study (COVIDENCE UK) . Vaccines vol. 10 , ( 10 ) 1601 - 1601 .
Vivaldi G, Jolliffe D, Tydeman F, Talaei M, Davies GA, Lyons RA, GRIFFITHS CJ, Kee F et al. ( 2022 ) . Risk factors for SARS-CoV-2 infection after primary vaccination with ChAdOx1 nCoV-19 or BNT1262b2 and after booster vaccination with BNT1262b2 or mRNA-1273: a population-based cohort study (COVIDENCE UK) . The Lancet Regional Health Europe
Martineau A ( 2022 ) . Behind the scenes at the Coronavit trial . BMJ vol. 378 ,
Jolliffe DA, Holt H, Greenig M, Talaei M, Perdek N, Pfeffer P, Vivaldi G, Maltby S et al. ( 2022 ) . Effect of a test-and-treat approach to vitamin D supplementation on risk of all cause acute respiratory tract infection and covid-19: Phase 3 randomised controlled trial (CORONAVIT) . The BMJ
Tydeman F, Pfeffer P, Vivaldi G, Holt H, Talaei M, Jolliffe D, Davies G, Lyons R et al. ( 2022 ) . Rebound in asthma exacerbations following relaxation of COVID-19 restrictions: a longitudinal population-based study (COVIDENCE UK) .
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young KS, Davies MR et al. ( 2022 ) . Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK) . Thorax vol. 77 , ( 9 ) 900 - 912 .
Jolliffe DA, Vivaldi G, Chambers ES, Cai W, Li W, Faustini SE, Gibbons JM, Pade C et al. ( 2022 ) . Vitamin D Supplementation Does Not Influence SARS-CoV-2 Vaccine Efficacy or Immunogenicity: Sub-Studies Nested within the CORONAVIT Randomised Controlled Trial . Nutrients vol. 14 , ( 18 )
Martineau AR, Cantorna MT ( 2022 ) . Vitamin D for COVID-19: where are we now? . Nature Reviews Immunology vol. 22 , ( 9 ) 529 - 530 .
Williamson AE, Tydeman F, Miners A, Pyper K, Martineau AR ( 2022 ) . Short-term and long-term impacts of COVID-19 on economic vulnerability: A population-based longitudinal study (COVIDENCE UK) . BMJ Open vol. 12 , ( 8 )
Evans RA, Leavy OC, Richardson M, Elneima O, McAuley HJC, Shikotra A, Singapuri A, Sereno M et al. ( 2022 ) . Clinical characteristics with inflammation profiling of long COVID and association with 1-year recovery following hospitalisation in the UK: a prospective observational study . The Lancet Respiratory Medicine vol. 10 , ( 8 ) 761 - 775 .
Vivaldi G, Jolliffe DA, Faustini S, Shields AM, Holt H, Perdek N, Talaei M, Tydeman F et al. ( 2022 ) . Correlation between post-vaccination anti-Spike antibody titres and protection against breakthrough SARS-CoV-2 infection: a population-based longitudinal study . J Infect Dis
Holt H, Relton C, Talaei M, Symons J, Davies M, Jolliffe D, Vivaldi G, Tydeman F et al. ( 2022 ) . Cohort Profile: Longitudinal population-based study of COVID-19 in UK adults (COVIDENCE UK) .
Lanham-New SA, Buttriss JL, Gibson-Moore H, Staines KA, Webb AR, Cashman KD, Hewison M, Martineau AR et al. ( 2022 ) . UK Nutrition Research Partnership ‘Hot Topic’ workshop: Vitamin D—A multi-disciplinary approach to (1) elucidate its role in human health and (2) develop strategies to improve vitamin D status in the UK population . Nutrition Bulletin vol. 47 , ( 2 ) 246 - 260 .
Calder PC, Berger MM, Gombart AF, McComsey GA, Martineau AR, Eggersdorfer M ( 2022 ) . Micronutrients to Support Vaccine Immunogenicity and Efficacy . Vaccines vol. 10 , ( 4 )
Stefanidis C, Bush A, Newby C, Nwokoro C, Liebeschuetz S, Skene IP, Griffiths CJ, Martineau AR ( 2022 ) . Vitamin D replacement in children with acute wheeze: a dose-escalation study . ERJ Open Research vol. 8 , ( 2 )
Jolliffe D, Holt H, Greenig M, Talaei M, Perdek N, Pfeffer P, Vivaldi G, Maltby S et al. ( 2022 ) . Vitamin D Supplements for Prevention of COVID-19 or other Acute Respiratory Infections: a Phase 3 Randomised Controlled Trial (CORONAVIT) .
Middelkoop K, Walker N, Stewart J, Delport C, Jolliffe DA, Nuttall J, Coussens AK, Naude CE et al. ( 2022 ) . Prevalence and Determinants of Vitamin D Deficiency in 1825 Cape Town Primary Schoolchildren: A Cross-Sectional Study . Nutrients vol. 14 , ( 6 )
Young KS, Purves KL, Hübel C, Davies MR, Thompson KN, Bristow S, Krebs G, Danese A et al. ( 2022 ) . Depression, anxiety and PTSD symptoms before and during the COVID-19 pandemic in the UK . Psychological Medicine
Butt MF, Younis S, Wu Z, Hadi SH, Latif A, Martineau AR ( 2021 ) . The relationship between seasonality, latitude and tuberculosis notifications in Pakistan . BMC Infectious Diseases vol. 21 , ( 1 )
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al. ( 2021 ) . Risk Factors for Developing COVID-19: A Population-Based Longitudinal Study (COVIDENCE UK) . Thorax
Burman M, Zenner D, Copas A, Goscé L, Haghparast-Bidgoli H, White P, Hickson V, Greyson O et al. ( 2021 ) . S39 Is the treatment of latent tuberculosis infection amongst recent migrants safe and effective in primary care? . Thorax vol. 76 , ( Suppl 2 ) a28 - a29 .
Evans RA, McAuley H, Harrison EM, Shikotra A, Singapuri A, Sereno M, Elneima O, Docherty AB et al. ( 2021 ) . Physical, cognitive, and mental health impacts of COVID-19 after hospitalisation (PHOSP-COVID): a UK multicentre, prospective cohort study . The Lancet Respiratory Medicine vol. 9 , ( 11 ) 1275 - 1287 .
Bater J, Bromage S, Jambal T, Tsendjav E, Lkhagvasuren E, Jutmann Y, Martineau AR, Ganmaa D ( 2021 ) . Prevalence and determinants of vitamin d deficiency in 9595 mongolian schoolchildren: A cross-sectional study . Nutrients vol. 13 , ( 11 )
Pham H, Waterhouse M, Baxter C, Romero B, McLeod D, Armstrong B, Ebeling P, English D et al. ( 2021 ) . 1378The effect of vitamin D supplementation on acute respiratory infection -analysis of the D-Health Trial . International Journal of Epidemiology vol. 50 , ( Supplement_1 )
Pham H, Waterhouse M, Baxter C, Romero B, McLeod D, Armstrong B, Ebeling P, English D et al. ( 2021 ) . The effect of vitamin D supplementation on acute respiratory infection -analysis of the D-Health Trial . INTERNATIONAL JOURNAL OF EPIDEMIOLOGY . vol. 50 ,
Bohrer AC, Castro E, Hu Z, Queiroz ATL, Tocheny CE, Assmann M, Sakai S, Nelson C et al. ( 2021 ) . Eosinophils are part of the granulocyte response in tuberculosis and promote host resistance in mice . Journal of Experimental Medicine vol. 218 , ( 10 )
Goletti D, Martineau AR ( 2021 ) . Pathogenesis and Immunology of Tuberculosis . Essential Tuberculosis ,
Raisi-Estabragh Z, Martineau A, Curtis E, Moon R, Darling A, Lanham-New S, Ward K, Cooper C et al. ( 2021 ) . Vitamin D and coronavirus disease 2019 (COVID-19): rapid evidence review . Aging Clinical and Experimental Research
Belay M, Tulu B, Younis S, Jolliffe DA, Tayachew D, Manwandu H, Abozen T, Tirfie EA et al. ( 2021 ) . Detection of Mycobacterium tuberculosis complex DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic tuberculosis contacts: an observational study . The Lancet Microbe vol. 2 , ( 6 ) e267 - e275 .
Burman M, Zenner D, Copas A, Goscé L, White P, Hickson V, Greyson O, Trathen D et al. ( 2021 ) . Is the Treatment of Latent Tuberculosis Infection Amongst Recent Migrants Safe and Effective in Primary Care? . Conference: D6. D006 CLINICAL AND TRANSLATIONAL ADVANCES IN TB AND NTMa1191 - a1191 .
Bird V, He FJ, Heritage P, Kelly P, MacGregor G, Martineau A, McCoy D, Montag D et al. ( 2021 ) . The United Kingdom's global health funding cuts will exacerbate inequities . Nat Microbiol
Belay M, Tulu B, Younis S, Jolliffe DA, Tayachew D, Manwandu H, Abozen T, Tirfie EA et al. ( 2021 ) . Detection of <i>M. tuberculosis</i> DNA in CD34-Positive Peripheral Blood Mononuclear Cells of Asymptomatic TB Contacts . The Lancet
Holt H, Talaei M, Greenig M, Zenner D, Symons J, Relton C, Young K, Davies M et al. ( 2021 ) . Risk factors for developing COVID-19: a population-based longitudinal study (COVIDENCE UK) .
Jolliffe D, Martineau A, GRIFFITHS C ( 2021 ) . Vitamin D supplementation to prevent acute respiratory infections: systematic review and meta-analysis of aggregate data from randomised controlled trials . Lancet Diabetes and Endocrinology
Bousquet J, Czarlewski W, Zuberbier T, Mullol J, Blain H, Cristol JP, De La Torre R, Pizarro Lozano N et al. ( 2021 ) . Potential Interplay between Nrf2, TRPA1, and TRPV1 in Nutrients for the Control of COVID-19 . International Archives of Allergy and Immunology vol. 182 , ( 4 ) 324 - 338 .
Tulu B, Zewede A, Belay M, Zeleke M, Girma M, Tegegn M, Ibrahim F, Jolliffe DA et al. ( 2021 ) . Epidemiology of Bovine Tuberculosis and Its Zoonotic Implication in Addis Ababa Milkshed, Central Ethiopia . Frontiers in Veterinary Science vol. 8 ,
Camargo CA, Toop L, Sluyter J, Lawes CMM, Waayer D, Khaw KT, Martineau AR, Scragg R ( 2021 ) . Effect of monthly vitamin d supplementation on preventing exacerbations of asthma or chronic obstructive pulmonary disease in older adults: Post hoc analysis of a randomized controlled trial . Nutrients vol. 13 , ( 2 ) 1 - 12 .
Holt H, Martineau A, Greenig M, Talaei M, Rajpoot S, Kayyale A, Rifai SE, Lloyd P et al. ( 2021 ) . S2 Vigorous exercise is protective against COVID-19: cross-sectional analysis of baseline data from 9,817 UK adults participating in the COVIDENCE UK study . Thorax . Conference: Predicting and stratifying COVID-19 using real world data vol. 76 , a4 - a4 .
Martineau A, Ameni G, Younis S, Jolliffe D, Mayito J, Abebe M, Huggett J, Reece S ( 2021 ) . S89 Detection of M. Tuberculosis DNA in CD34-positive peripheral blood mononuclear cells of asymptomatic TB contacts . Thorax . Conference: TB: still playing the long game vol. 76 , a54 - a55 .
Pham H, Waterhouse M, Baxter C, Duarte Romero B, McLeod DSA, Armstrong BK, Ebeling PR, English DR et al. ( 2021 ) . The effect of vitamin D supplementation on acute respiratory tract infection in older Australian adults: an analysis of data from the D-Health Trial . Lancet Diabetes and Endocrinology vol. 9 , ( 2 ) 69 - 81 .
Tulu B, Martineau HM, Zewude A, Desta F, Jolliffe DA, Abebe M, Balcha TT, Belay M et al. ( 2020 ) . Cellular and cytokine responses in the granulomas of asymptomatic cattle naturally infected with mycobacterium bovis in Ethiopia . Infection and Immunity vol. 88 , ( 12 )
Bousquet J, Cristol JP, Czarlewski W, Anto JM, Martineau A, Haahtela T, Fonseca SC, Iaccarino G et al. ( 2020 ) . Nrf2-interacting nutrients and COVID-19: time for research to develop adaptation strategies . Clinical and Translational Allergy vol. 10 , ( 1 )
Jolliffe DA, Camargo CA, Sluyter JD, Aglipay M, Aloia JF, Ganmaa D, Bergman P, Borzutzky A et al. ( 2020 ) . Vitamin D supplementation to prevent acute respiratory infections: systematic review and meta-analysis of aggregate data from randomised controlled trials . United States , Abstract: java.sql.Clob org.hibernate.engine.jdbc.WrappedClob java.io.Serializable ,
Chambers E, Vukmanovic-Stejic M, Turner C, Shih B, Trahair H, Pollara G, Tsaliki E, Rustin M et al. ( 2020 ) . Vitamin D3 replacement enhances antigen-specific immunity in older adults . Immunotherapy Advances Article ltaa008 , 1 - 1 .
Panagiotou G, Tee SA, Ihsan Y, Athar W, Marchitelli G, Kelly D, Boot CS, Stock N et al. ( 2020 ) . Original publication: Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalized with COVID-19 are associated with greater disease severity . Clinical Endocrinology vol. 93 , ( 5 ) 629 - 630 .
Ganmaa D, Gantsetseg G, Khulan D, Ariunzaya S, Delgereh B, Sumiya E, Amarsaikhan B, Martineau A ( 2020 ) . G582 Phase 3 randomised controlled trial of vitamin D supplementation in 8,851 mongolian schoolchildren . Archives of Disease in Childhood . Conference: Abstracts vol. 105 , a209 - a209 .
Panagiotou G, Tee SA, Ihsan Y, Athar W, Marchitelli G, Kelly D, Boot CS, Stock N et al. ( 2020 ) . Low serum 25-hydroxyvitamin D (25[OH]D) levels in patients hospitalized with COVID-19 are associated with greater disease severity . Clinical Endocrinology vol. 93 , ( 4 ) 508 - 511 .
Patterson B, Smith D, Telford A, Tana A, Johnstone D, Davidson R, Martineau AR ( 2020 ) . Vitamin D deficiency predicts latent TB reactivation independent of preventive therapy: A longitudinal study . International Journal of Tuberculosis and Lung Disease vol. 24 , ( 9 ) 916 - 921 .
Camargo CA, Martineau AR ( 2020 ) . Vitamin D to prevent COVID-19: recommendations for the design of clinical trials . FEBS Journal vol. 287 , ( 17 ) 3689 - 3692 .
Martineau AR, Forouhi NG ( 2020 ) . Vitamin D for COVID-19: a case to answer? . Lancet Diabetes and Endocrinology vol. 8 , ( 9 ) 735 - 736 .
Jolliffe DA, Stefanidis C, Wang Z, Kermani NZ, Dimitrov V, White JH, McDonough JE, Janssens W et al. ( 2020 ) . Vitamin D Metabolism Is Dysregulated in Asthma and Chronic Obstructive Pulmonary Disease . American journal of respiratory and critical care medicine vol. 202 , ( 3 ) 371 - 382 .
Ganmaa D, Uyanga B, Zhou X, Gantsetseg G, Delgerekh B, Enkhmaa D, Khulan D, Ariunzaya S et al. ( 2020 ) . Vitamin D supplements for prevention of tuberculosis infection and disease . New England Journal of Medicine vol. 383 , ( 4 ) 359 - 368 .
Bhala N, Curry G, Martineau AR, Agyemang C, Bhopal R ( 2020 ) . Sharpening the global focus on ethnicity and race in the time of COVID-19 . The Lancet vol. 395 , ( 10238 ) 1673 - 1676 .
Peto J, Alwan NA, Godfrey KM, Burgess RA, Hunter DJ, Riboli E, Romer P, Buchan I et al. ( 2020 ) . Universal weekly testing as the UK COVID-19 lockdown exit strategy . The Lancet vol. 395 , ( 10234 ) 1420 - 1421 .
Ganmaa D, Sumiya E, Ankhbat M, Gantungalag G, Zhou X, Erdenetuya G, Martineau A ( 2020 ) . Vitamin D Supplementation and Respiratory Health Outcomes: A Phase 3 Randomized Trial of Vitamin D Supplementation in 8,851 Mongolian Schoolchildren . Conference: A19. TUBERCULOSIS SCIENCE HIGHLIGHTSa1053 - a1053 .
Alwan NA, Bhopal R, Burgess RA, Colburn T, Cuevas LE, Smith GD, Egger M, Eldridge S et al. ( 2020 ) . Evidence informing the UK's COVID-19 public health response must be transparent . The Lancet vol. 395 , ( 10229 ) 1036 - 1037 .
Garcia Gonzalez J, Brock A, Parker M, Riley R, Joliffe D, SUDWARTS A, Teh M-T, Busch-Nentwich E et al. ( 2020 ) . Identification of Slit3 as a locus affecting nicotine preference in zebrafish and human smoking behaviour . eLife
Roe J, Venturini C, Gupta RK, Gurry C, Chain BM, Sun Y, Southern J, Jackson C et al. ( 2020 ) . Blood transcriptomic stratification of short-term risk in contacts of tuberculosis . Clinical Infectious Diseases vol. 70 , ( 5 ) 731 - 737 .
Lone NM, Riaz S, Eusaph AZ, Mein CA, Wozniak EL, Xenakis T, Wu Z, Younis S et al. ( 2020 ) . Genotype-independent association between vitamin D deficiency and polycystic ovarian syndrome in Lahore, Pakistan . Scientific Reports vol. 10 , ( 1 )
Rake C, Gilham C, Bukasa L, Ostler R, Newton M, Wild JP, Aigret B, Hill M et al. ( 2020 ) . High-dose oral vitamin d supplementation and mortality in people aged 65–84 years: The vidal cluster feasibility rct of open versus double-blind individual randomisation . Health Technology Assessment vol. 24 , ( 10 ) 1 - 53 .
Taylor EH, Gandhi B, Marleen S, Hooper RL, Aquilina J, Martineau AR ( 2020 ) . Seasonal variation in fetal lateral cerebral ventricular diameter . Prenatal Diagnosis vol. 40 , ( 3 ) 390 - 392 .
Mayito J, Andia Biraro I, T Reece S, R Martineau A, P Kateete D ( 2020 ) . Detection of Mycobacterium tuberculosis DNA in CD34 + peripheral blood mononuclear cells of Ugandan adults with latent infection: a cross-sectional and nested prospective study . AAS Open Res vol. 3 ,
Burman M, Copas A, Zenner D, Hickson V, Gosce L, Trathen D, Ashcroft R, Martineau AR et al. ( 2019 ) . Protocol for a cluster randomised control trial evaluating the efficacy and safety of treatment for latent tuberculosis infection in recent migrants within primary care: the CATAPuLT trial . BMC Public Health vol. 19 , Article 1 , 1598 - 1598 .
Ganmaa D, Khudyakov P, Buyanjargal U, Jargalsaikhan B, Baigal D, Munkhjargal O, Yansan N, Bolormaa S et al. ( 2019 ) . Prevalence and Determinants of QuantiFERON-Diagnosed Tuberculosis Infection in 9810 Mongolian Schoolchildren . Clinical Infectious Diseases vol. 69 , ( 5 ) 813 - 819 .
Martineau AR, Thummel KE, Wang Z, Jolliffe DA, Boucher BJ, Griffin SJ, Forouhi NG, Hitman GA ( 2019 ) . Differential Effects of Oral Boluses of Vitamin D<inf>2</inf> vs Vitamin D<inf>3</inf> on Vitamin D Metabolism: A Randomized Controlled Trial . Journal of Clinical Endocrinology and Metabolism vol. 104 , ( 12 ) 5831 - 5839 .
Griffiths C, Stefanidis C, Martineau AR, NWOKORO C, BUSH A ( 2019 ) . Vitamin D for secondary prevention of acute wheeze attacks in preschool and school-age children . Thorax vol. 74 , ( 10 )
Ganmaa D, Khudyakov P, Buyanjargal U, Baigal D, Baatar M, Enkhamgalan N, Erdenebaatar S, Ochirbat B et al. ( 2019 ) . Risk factors for active tuberculosis in 938 QuantiFERON-positive schoolchildren in Mongolia: A community-based cross-sectional study . BMC Infectious Diseases vol. 19 , ( 1 )
Kim EW, De Leon A, Jiang Z, Radu RA, Martineau AR, Chan ED, Bai X, Su WL et al. ( 2019 ) . Vitamin A metabolism by dendritic cells triggers an antimicrobial response against Mycobacterium tuberculosis . mSphere vol. 4 , ( 3 )
Jolliffe DA, Greenberg L, Hooper RL, Mathyssen C, Rafiq R, De Jongh RT, Camargo CA, Griffiths CJ et al. ( 2019 ) . Vitamin D to prevent exacerbations of COPD: Systematic review and meta-analysis of individual participant data from randomised controlled trials . Thorax vol. 74 , ( 4 ) 337 - 345 .
Martineau AR, Cates CJ, Jolliffe D, Janssens W, Sheikh A, Griffiths CJ ( 2019 ) . Vitamin D for the management of chronic obstructive pulmonary disease . Cochrane Database of Systematic Reviews vol. 2019 , ( 3 )
Greiller CL, Suri R, Jolliffe DA, Kebadze T, Hirsman AG, Griffiths CJ, Johnston SL, Martineau AR ( 2019 ) . Vitamin D attenuates rhinovirus-induced expression of intercellular adhesion molecule-1 (ICAM-1) and platelet-activating factor receptor (PAFR) in respiratory epithelial cells . Journal of Steroid Biochemistry and Molecular Biology vol. 187 , 152 - 159 .
MARTINEAU AR ( 2019 ) . Vitamin D supplementation and musculoskeletal health . Lancet Diabetes and Endocrinology vol. 7 , ( 2 ) 86 - 87 .
Martineau AR, Jolliffe DA, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S, Ganmaa D et al. ( 2019 ) . Vitamin D supplementation to prevent acute respiratory infections: Individual participant data meta-analysis . Health Technology Assessment vol. 23 , ( 2 ) 1 - 44 .
Jolliffe DA, Ganmaa D, Wejse C, Raqib R, Haq MA, Salahuddin N, Daley PK, Ralph AP et al. ( 2018 ) . Adjunctive vitamin D in tuberculosis treatment: meta-analysis of individual participant data . Eur Respir J vol. 53 , ( 3 )
Parekh D, Dancer RCA, Scott A, D'Souza VK, Howells PA, Mahida RY, Tang JCY, Cooper MS et al. ( 2018 ) . Vitamin D to Prevent Lung Injury Following Esophagectomy-A Randomized, Placebo-Controlled Trial . Crit Care Med vol. 46 , ( 12 ) e1128 - e1135 .
MARTINEAU AR, Mayito J, Andia I, Belay M, JOLLIFFE DA, Kateete D, Reece S ( 2018 ) . Anatomic and Cellular Niches for Mycobacterium tuberculosis in Latent Tuberculosis Infection . Journal of Infectious Diseases Article 30376080 ,
Roth DE, Abrams SA, Aloia J, Bergeron G, Bourassa MW, Brown KH, Calvo MS, Cashman KD et al. ( 2018 ) . Global prevalence and disease burden of vitamin D deficiency: a roadmap for action in low-and middle-income countries . Annals of the New York Academy of Sciences vol. 1430 , ( 1 ) 44 - 79 .
Jolliffe DA, Greiller CL, Mein CA, Hoti M, Bakhsoliani E, Telcian AG, Simpson A, Barnes NC et al. ( 2018 ) . Vitamin D receptor genotype influences risk of upper respiratory infection . Br J Nutr1 - 10 .
Brighenti S, Bergman P, Martineau AR ( 2018 ) . Vitamin D and tuberculosis: where next? . Journal of Internal Medicine vol. 284 , ( 2 ) 145 - 162 .
Pilz S, März W, Cashman KD, Kiely ME, Whiting SJ, Holick MF, Grant WB, Pludowski P et al. ( 2018 ) . Rationale and Plan for Vitamin D Food Fortification: A Review and Guidance Paper . Frontiers in Endocrinology vol. 9 , 373 - 373 .
Martineau A ( 2018 ) . Vitamin D supplementation to prevent asthma exacerbations – Authors' reply . The Lancet Respiratory Medicine vol. 6 , ( 6 ) e26 - e27 .
Saleem J, Zakar R, Zakar MZ, Belay M, Rowe M, Timms PM, Scragg R, Martineau AR ( 2018 ) . High-dose Vitamin D 3 in the treatment of severe acute malnutrition: A multicenter double-blind randomized controlled trial . American Journal of Clinical Nutrition vol. 107 , ( 5 ) 725 - 733 .
MARTINEAU AR, Lowe D, DEMARET J ( 2018 ) . Differential effect of Viable Versus necrotic neutrophils on Mycobacterium tuberculosis growth and cytokine induction in Whole Blood . Frontiers in Immunology
Martineau AR, Jolliffe DA, Demaret J ( 2018 ) . Chapter 103 Vitamin D and Tuberculosis . Vitamin D ,
Chambers ES, Nanzer AM, Pfeffer PE, Richards DF, Martineau AR, Griffiths CJ, Corrigan CJ, Hawrylowicz CM ( 2018 ) . Dendritic cell phenotype in severe asthma reflects clinical responsiveness to glucocorticoids . Clinical and Experimental Allergy vol. 48 , ( 1 ) 13 - 22 .
Martineau A ( 2018 ) . Vitamin D and Respiratory Infections . ANNALS OF NUTRITION AND METABOLISM . vol. 73 , 191 - 192 .
Martineau AR, Jolliffe DA, Demaret J ( 2017 ) . Vitamin D and Tuberculosis . Vitamin D: Fourth Edition , vol. 2 ,
Jolliffe DA, Greenberg L, Hooper RL, Griffiths CJ, Camargo CA, Kerley CP, Jensen ME, Mauger D et al. ( 2017 ) . Vitamin D supplementation to prevent asthma exacerbations: a systematic review and meta-analysis of individual participant data . The Lancet Respiratory Medicine vol. 5 , ( 11 ) 881 - 890 .
Ganmaa D, Munkhzul B, Fawzi W, Spiegelman D, Willett WC, Bayasgalan P, Baasansuren E, Buyankhishig B et al. ( 2017 ) . High-Dose Vitamin D3 During Tuberculosis Treatment in Mongolia: A Randomised Controlled Trial . Am J Respir Crit Care Med
Balcells ME, Cerda J, Concha S, Hoyos-Bachiloglu R, Camargo CA, Martineau AR, Borzutzky A ( 2017 ) . Regional solar radiation is inversely correlated with incidence and severity of tuberculosis in Chile . Epidemiol Infect vol. 145 , ( 9 ) 1815 - 1823 .
Ganmaa D, Khudyakov P, Munkhjarga O, Jargalsaikhan B, Baigal D, Ochirbat B, Buyanjargal U, Martineau A ( 2017 ) . Risk factors for M. tuberculosis infection in vitamin D deficient Mongolian school children . FASEB JOURNAL . vol. 31 ,
MARTINEAU AR, JOLLIFFE DA, HOOPER RL, GREENBERG L, GRIFFITHS CJ ( 2017 ) . Vitamin D supplementation to prevent acute respiratory tract infections: systematic review and meta-analysis of individual participant data . BMJ
Coussens A, Naude C, Chaplin G, Noursadeghi M, Martineau A, Jablonski N, Wilkinson R ( 2017 ) . VITAMIN D FOR TREATMENT AND PREVENTION OF TB-HIV . BMJ Global Health vol. 2 , ( Suppl 2 )
Jolliffe DA, James WY, Hooper RL, Barnes NC, Greiller CL, Islam K, Bhowmik A, Timms PM et al. ( 2017 ) . Prevalence, determinants and clinical correlates of vitamin D deficiency in patients with Chronic Obstructive Pulmonary Disease in London, UK . Journal of Steroid Biochemistry and Molecular Biology
Martineau A, Jolliffe D, Hooper R, Greenberg L, Aloia J, Bergman P, Dubnov-Raz G, Esposito S et al. ( 2016 ) . S102 Vitamin d supplementation to prevent acute respiratory infections: systematic review and meta-analysis of individual participant data . Thorax . vol. 71 ,
Ganmaa D, Munkhsul B, Bromage S, Buyankhishig B, Martineau A ( 2016 ) . S113 High-dose vitamin D3 during intensive phase treatment of pulmonary tuberculosis in mongolia: a double-blind randomised controlled trial . Thorax . vol. 71 ,
Martineau A, Cates C, Urashima M, Jensen M, Griffiths A, Nurmatov U, Sheikh A, Griffiths C ( 2016 ) . S5 Vitamin d for the management of asthma: cochrane systematic review and meta-analysis . vol. 71 , is. Suppl 3 ,
Jolliffe DA, Kilpin K, MacLaughlin BD, Greiller CL, Hooper RL, Barnes NC, Timms PM, Rajakulasingam RK et al. ( 2016 ) . Prevalence, determinants and clinical correlates of vitamin D deficiency in adults with inhaled corticosteroid-treated asthma in London, UK . J Steroid Biochem Mol Biol
Jolliffe DA, Hanifa Y, Witt KD, Venton TR, Rowe M, Timms PM, Hyppönen E, Walton RT et al. ( 2016 ) . Environmental and genetic determinants of vitamin D status among older adults in London, UK . Journal of Steroid Biochemistry and Molecular Biology vol. 164 , 30 - 35 .
Bangani N, Nakiwala J, Martineau AR, Wilkinson RJ, Wilkinson KA, Lowe DM ( 2016 ) . HIV-1 Infection Impairs CD16 and CD35 Mediated Opsonophagocytosis of Mycobacterium tuberculosis by Human Neutrophils . JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES vol. 73 , ( 3 ) 263 - 267 .
Jolliffe DA, Walton RT, Griffiths CJ, Martineau AR ( 2016 ) . Single nucleotide polymorphisms in the vitamin D pathway associating with circulating concentrations of vitamin D metabolites and non-skeletal health outcomes: Review of genetic association studies . Journal of Steroid Biochemistry and Molecular Biology vol. 164 , 18 - 29 .
Roe JK, Thomas N, Gil E, Best K, Tsaliki E, Morris‑Jones S, Stafford S, Simpson N et al. ( 2016 ) . Blood transcriptomic diagnosis of pulmonary and extrapulmonary tuberculosis . JCI Insight vol. 1 , ( 16 )
Martineau AR, Cates CJ, Urashima M, Jensen M, Griffiths AP, Nurmatov U, Sheikh A, Griffiths CJ ( 2016 ) . Vitamin D for the management of asthma . Cochrane Database Syst Rev vol. 9 , CD011511 - CD011511 .
Martineau AR, Jolliffe DA, Hooper RL, Greenberg L, Aloia JF, Bergman P, Dubnov-Raz G, Esposito S et al. ( 2016 ) . Protective effects of vitamin D supplementation against acute respiratory infection are greatest in those with the lowest baseline vitamin D status . Conference: 1.13 Clinical Problems - Other
Bangani N, Nakiwala J, Martineau AR, Wilkinson RJ, Wilkinson KA, Lowe DM ( 2016 ) . HIV-1 infection impairs CD16 and CD35 mediated opsonophagocytosis of M.tuberculosis by human neutrophils . JAIDS Journal of Acquired Immune Deficiency Syndromes1 - 1 .
Junaid K, Rehman A, Jolliffe DA, Saeed T, Wood K, Martineau AR ( 2016 ) . Vitamin D deficiency associates with susceptibility to tuberculosis in Pakistan, but polymorphisms in VDR, DBP and CYP2R1 do not . BMC Pulmonary Medicine vol. 16 , ( 1 )
Forouhi NG, Menon RK, Sharp SJ, Mannan N, Timms PM, Martineau AR, Rickard AP, Boucher BJ et al. ( 2016 ) . Effects of vitamin D<inf>2</inf> or D<inf>3</inf> supplementation on glycaemic control and cardiometabolic risk among people at risk of type 2 diabetes: Results of a randomized double-blind placebo-controlled trial . Diabetes, Obesity and Metabolism vol. 18 , ( 4 ) 392 - 400 .
Griffiths M, Goldring S, Griffiths C, Shaheen SO, Martineau A, Cross L, Robinson S, Warner JO et al. ( 2015 ) . Effects of pre-Natal Vitamin D supplementation with partial correction of Vitamin D deficiency on early life healthcare utilisation: A randomised controlled trial . PLoS ONE vol. 10 , ( 12 )
Pareek M, Innes J, Sridhar S, Grass L, Connell D, Woltmann G, Wiselka M, Martineau AR et al. ( 2015 ) . Vitamin D deficiency and TB disease phenotype . Thorax vol. 70 , ( 12 ) 1171 - 1180 .
Lowe DM, Bangani N, Goliath R, Kampmann B, Wilkinson KA, Wilkinson RJ, Martineau AR ( 2015 ) . Effect of antiretroviral therapy on HIV-mediated impairment of the neutrophil antimycobacterial response . Annals of the American Thoracic Society vol. 12 , ( 11 ) 1627 - 1637 .
Junaid K, Rehman A, Jolliffe DA, Wood K, Martineau AR ( 2015 ) . High prevalence of vitamin D deficiency among women of child-bearing age in Lahore Pakistan, associating with lack of sun exposure and illiteracy . BMC Women's Health vol. 15 , ( 1 )
Martineau AR, Hanifa Y, Witt KD, Barnes NC, Hooper RL, Patel M, Stevens N, Enayat Z et al. ( 2015 ) . Double-blind randomised controlled trial of vitamin D<inf>3</inf> supplementation for the prevention of acute respiratory infection in older adults and their carers (ViDiFlu) . Thorax vol. 70 , ( 10 ) 953 - 960 .
Chambers ES, Nanzer AM, Pfeffer PE, Richards DF, Timms PM, Martineau AR, Griffiths CJ, Corrigan CJ et al. ( 2015 ) . Distinct endotypes of steroid-resistant asthma characterized by IL-17A<sup>high</sup> and IFN-γ<sup>high</sup> immunophenotypes: Potential benefits of calcitriol . Journal of Allergy and Clinical Immunology vol. 136 , ( 3 ) 628 - 637.e4 .
James WY, Greiller C, MacLaughlin B, Barnes N, Rajakulasingam R, Bhowmik A, Choudhury A, Simcock D et al. ( 2015 ) . Peripheral blood eosinophilia predicts lower airway eosinophilia in asthma and COPD . Conference: 3.2 Airway Cell Biology and Immunopathology
Martineau AR ( 2015 ) . Vitamin D and tuberculosis . TROPICAL MEDICINE & INTERNATIONAL HEALTH vol. 20 , 78 - 78 .
Davies PDO, Martineau AR ( 2015 ) . Vitamin D and tuberculosis: More effective in prevention than treatment? . International Journal of Tuberculosis and Lung Disease vol. 19 , ( 8 )
Martineau AR, Hooper RL ( 2015 ) . Vitamin D supplementation in patients with COPD: Twitter discussions on behalf of the University of Toronto Respirology and Sleep Journal Club - Authors' Reply . The Lancet Respiratory Medicine vol. 3 , ( 8 ) e24 - e25 .
Junaid K, Rehman A, Saeed T, Jolliffe DA, Wood K, Martineau AR ( 2015 ) . Genotype-independent association between profound vitamin D deficiency and delayed sputum smear conversion in pulmonary tuberculosis . BMC Infectious Diseases vol. 15 , ( 1 )
Coussens AK, Wilkinson RJ, Martineau AR ( 2015 ) . Phenylbutyrate Is Bacteriostatic against Mycobacterium tuberculosis and Regulates the Macrophage Response to Infection, Synergistically with 25-Hydroxy-Vitamin D₃ . PLoS Pathogens vol. 11 , ( 7 )
Dancer RCA, Parekh D, Lax S, D'Souza V, Zheng S, Bassford CR, Park D, Bartis DG et al. ( 2015 ) . Vitamin D deficiency contributes directly to the acute respiratory distress syndrome (ARDS) . Thorax vol. 70 , ( 7 ) 617 - 624 .
Raftery T, Martineau AR, Greiller CL, Ghosh S, McNamara D, Bennett K, Meddings J, O’Sullivan M ( 2015 ) . Effects of vitamin D supplementation on intestinal permeability, cathelicidin and disease markers in Crohn’s disease: Results from a randomised double-blind placebo-controlled study . United European Gastroenterology Journal vol. 3 , ( 3 ) 294 - 302 .
Leber W, McMullen H, Marlin N, Bremner S, Boomla K, Kerry S, Martineau A, Griffi C et al. ( 2015 ) . Promotion of rapid testing for HIV in primary care (RHIVA2): A cluster-randomised controlled trial . The Lancet HIV vol. 2 , ( 6 ) e229 - e235 .
Greiller CL, Martineau AR ( 2015 ) . Modulation of the immune response to respiratory viruses by vitamin D . Nutrients vol. 7 , ( 6 ) 4240 - 4270 .
Martineau AR, MacLaughlin BD, Hooper RL, Barnes NC, Jolliffe DA, Greiller CL, Kilpin K, McLaughlin D et al. ( 2015 ) . Double-blind randomised placebo-controlled trial of bolus-dose vitamin D<inf>3</inf> supplementation in adults with asthma (ViDiAs) . Thorax vol. 70 , ( 5 ) 451 - 457 .
Leber W, McMullen H, Anderson J, Marlin N, Santos AC, Bremner S, Boomla K, Kerry S et al. ( 2015 ) . Promotion of rapid testing for HIV in primary care (RHIVA2): a cluster-randomised controlled trial . The Lancet HIV vol. 2 , ( 6 ) e229 - e235 .
Martineau AR ( 2015 ) . 'Curiouser and curiouser': The role of vitamin D in the prevention of acute respiratory infection . Acta Paediatrica, International Journal of Paediatrics vol. 104 , ( 4 ) 331 - 333 .
Martineau A, Takeda A, Nurmatov U, Sheikh A, Griffiths CJ ( 2015 ) . Vitamin D for the management of asthma . Cochrane Database of Systematic Reviews vol. 2015 , ( 3 )
Martineau AR, James WY, Hooper RL, Barnes NC, Jolliffe DA, Greiller CL, Islam K, McLaughlin D et al. ( 2015 ) . Vitamin D<inf>3</inf> supplementation in patients with chronic obstructive pulmonary disease (ViDiCO): A multicentre, double-blind, randomised controlled trial . The Lancet Respiratory Medicine vol. 3 , ( 2 ) 120 - 130 .
Kotta S, Gadhvi D, Jakeways N, Saeed M, Sohanpal R, Hull S, Famakin O, Martineau A et al. ( 2015 ) . Test me and treat me - Attitudes to vitamin D deficiency and supplementation: A qualitative study . BMJ Open vol. 5 , ( 7 )
Chambers ES, Nanzer AM, Pfeffer PE, Richards DF, Martineau AR, Griffiths CJ, Corrigan CJ, Hawrylowicz CM ( 2014 ) . Calcitriol restores glucocorticoid responsiveness in steroid resistant asthmatics through reduction of IL-17A . IMMUNOLOGY . vol. 143 , 50 - 50 .
Jolliffe D, Martineau A, James W, Islam K, Mein C, Timms P, Walton R, Griffiths C ( 2014 ) . M145 Prevalence And Determinants Of Vitamin D Deficiency In Patients With Chronic Obstructive Pulmonary Disease . Thorax . vol. 69 , a215 - a216 .
Jolliffe D, Martineau A, Maclaughlin B, Kiplin K, Timms P, Mein C, Walton R, Griffiths C ( 2014 ) . P48 Prevalence And Determinants Of Vitamin D Deficiency In Asthma Patients . Thorax . vol. 69 , a94 - a95 .
Martineau A, James W, Hooper R, Barnes N, Jolliffe D, Bhowmik A, Rajakulasingam R, Choudhury et al. ( 2014 ) . S104 Double-blind Multi-centre Randomised Controlled Trial Of Vitamin D3 Supplementation In Copd (vidico) . Thorax . vol. 69 , a55 - a56 .
Martineau A, MacLaughlin B, Hooper R, Barnes N, Jolliffe D, Choudhury, Rajakulasingam R, Bhowmik A et al. ( 2014 ) . S95 Double-blind Multi-centre Randomised Controlled Trial Of Vitamin D3 Supplementation In Adults With Inhaled Corticosteroid-treated Asthma (vidias) . Thorax . vol. 69 , a51 - a52 .
Cassidy JP, Martineau AR ( 2014 ) . Innate resistance to tuberculosis in man, cattle and laboratory animal models: nipping disease in the bud? . J Comp Pathol vol. 151 , ( 4 ) 291 - 308 .
Martineau AR ( 2014 ) . Design and analysis of clinical trials of nutrients: commentary . Nutr Rev vol. 72 , ( 5 )
Martineau A ( 2014 ) . The role of vitamin D in tuberculosis pathogenesis and treatment . International Journal of Infectious Diseases vol. 21 ,
Martineau AR, Khan K ( 2014 ) . Maternal vitamin D insufficiency is associated with adverse pregnancy and neonatal outcomes . Evid Based Med vol. 19 , ( 1 )
Martineau A, Jolliffe D ( 2014 ) . "Vitamin D and Human Health: from the Gamete to the Grave": Report on a meeting held at Queen Mary University of London, 23rd-25th April 2014 . Nutrients vol. 6 , ( 7 ) 2759 - 2919 .
Coussens AK, Martineau AR, Wilkinson RJ ( 2014 ) . Anti-Inflammatory and Antimicrobial Actions of Vitamin D in Combating TB/HIV . Scientifica (Cairo) vol. 2014 ,
Martineau A ( 2014 ) . Of Badgers and Men: Vitamin D and Immunity to mycobacteria . Journal of Comparative Pathology vol. 150 , ( 1 )
Nanzer AM, Chambers ES, Ryanna K, Freeman AT, Colligan G, Richards DF, Timms PM, Martineau AR et al. ( 2014 ) . The effects of calcitriol treatment in glucocorticoid-resistant asthma . Journal of Allergy and Clinical Immunology
Nanzer AM, Chambers ES, Richards DF, Martineau AR, Griffiths CJ, Corrigan C, Hawrylowicz CM ( 2013 ) . A ROLE FOR ACTIVE VITAMIN D IN STEROID RESISTANT ASTHMA PATIENTS WHO HAVE ENHANCED PRODUCTION OF IL-17A AND REDUCED IL-10 . THORAX . vol. 68 , A163 - A163 .
Martineau AR, Hanifa Y, Hooper RL, Witt KD, Patel M, Syed A, Jolliffe DA, Timms PM et al. ( 2013 ) . INCREASED RISK OF UPPER RESPIRATORY INFECTION WITH ADDITION OF INTERMITTENT BOLUS-DOSE VITAMIN D SUPPLEMENTATION TO A DAILY LOW-DOSE REGIMEN . THORAX . vol. 68 , A64 - A64 .
Lowe DM, Bandara AK, Packe GE, Barker RD, Wilkinson RJ, Griffiths CJ, Martineau AR ( 2013 ) . Neutrophilia independently predicts death in tuberculosis . Eur Respir J vol. 42 , ( 6 ) 1752 - 1757 .
Witt KD, Jolliffe DA, Wang Z, Thummel KE, Timms PM, Griffiths CJ, Martineau AR ( 2013 ) . VITAMIN D STATUS IMPROVES FOLLOWING RECOVERY FROM TUBERCULOSIS . THORAX . vol. 68 , A115 - A116 .
Leber W, McMullen H, Marlin N, Bremner S, Santos AC, Terris-Prestholt F, Boomla K, Ashcroft R et al. ( 2013 ) . Point-of-care HIV testing in primary care and early detection of HIV (RHIVA2): a cluster randomised controlled trial . LANCET . vol. 382 , 7 - 7 .
Menon RK, Rickard AP, Mannan N, Timms PM, Sharp SJ, Martineau A, Boucher BJ, Chowdhury TA et al. ( 2013 ) . The effects of vitamin D₂ or D₃ supplementation on glycaemic control and related metabolic parameters in people at risk of type 2 diabetes: protocol of a randomised double-blind placebo-controlled trial . BMC Public Health vol. 13 ,
Dancer R, Parekh D, Martineau A, Perkins G, Thickett D ( 2013 ) . Effects of high dose vitamin D supplementation in patients undergoing oesophagectomy . EUROPEAN RESPIRATORY JOURNAL vol. 42 ,
Rajan N, Alam J, Brugha R, Greiller C, James WY, Martineau A, Grigg J ( 2013 ) . In vivo macrophage phagocytosis of inhaled black carbon air pollution in COPD . EUROPEAN RESPIRATORY JOURNAL vol. 42 ,
James WY, Jolliffe D, Islam K, Greiller C, Martineau A ( 2013 ) . Safety and efficacy of sputum induction in COPD patients . EUROPEAN RESPIRATORY JOURNAL vol. 42 ,
Nanzer AM, Chambers ES, Ryanna K, Richards DF, Black C, Timms PM, Martineau AR, Griffiths CJ et al. ( 2013 ) . Enhanced production of IL-17A in patients with severe asthma is inhibited by 1α,25-dihydroxyvitamin D3 in a glucocorticoid-independent fashion . J Allergy Clin Immunol vol. 132 , ( 2 ) 297 - 304.e3 .
Kuan V, Martineau AR, Griffiths CJ, Hyppönen E, Walton R ( 2013 ) . DHCR7 mutations linked to higher vitamin D status allowed early human migration to northern latitudes . BMC Evol Biol vol. 13 ,
Jolliffe DA, Griffiths CJ, Martineau AR ( 2013 ) . Vitamin D in the prevention of acute respiratory infection: systematic review of clinical studies . J Steroid Biochem Mol Biol vol. 136 , 321 - 329 .
Briggs ADM, Kuan V, Greiller CL, Maclaughlin BD, Ramachandran M, Harris T, Timms PM, Venton TR et al. ( 2013 ) . Longitudinal study of vitamin D metabolites after long bone fracture . J Bone Miner Res vol. 28 , ( 6 ) 1301 - 1307 .
Parekh D, Dancer RCA, Lax S, Cooper MS, Martineau AR, Fraser WD, Tucker O, Alderson D et al. ( 2013 ) . Vitamin D to prevent acute lung injury following oesophagectomy (VINDALOO): study protocol for a randomised placebo controlled trial . TRIALS vol. 14 , Article ARTN 100 ,
Martineau AR, Jolliffe DA ( 2013 ) . Genetic variants modifying the influence of vitamin D . JAMA vol. 309 , ( 9 ) 872 - 873 .
Lowe DM, Bangani N, Mehta MR, Lang DM, Rossi AG, Wilkinson KA, Wilkinson RJ, Martineau AR ( 2013 ) . A novel assay of antimycobacterial activity and phagocytosis by human neutrophils . Tuberculosis (Edinb) vol. 93 , ( 2 ) 167 - 178 .
Finer S, Khan KS, Hitman GA, Griffiths C, Martineau A, Meads C ( 2013 ) . Inadequate Vitamin D Status in Pregnancy . Obstetric Anesthesia Digest vol. 33 , ( 1 )
Martineau AR ( 2013 ) . Vitamin D: an adjunct to antiretroviral therapy? . J Infect Dis vol. 207 , ( 3 ) 373 - 375 .
Raftery T, Martineau A, Greiller C, Lee CS, McNamara D, Ghosh S, Meddings J, O'sullivan M ( 2013 ) . Does vitamin D supplementation impact plasma cathelicidin, human beta defensin 2 and intestinal permeability in stable Crohn's disease? - Results from a randomised, double blind placebo controlled study . PROCEEDINGS OF THE NUTRITION SOCIETY vol. 72 , ( OCE3 ) E176 - E176 .
Coussens AK, Wilkinson RJ, Nikolayevskyy V, Elkington PT, Hanifa Y, Islam K, Timms PM, Bothamley GH et al. ( 2013 ) . Ethnic variation in inflammatory profile in tuberculosis . PLoS Pathog vol. 9 , ( 7 )
Goldring ST, Griffiths CJ, Martineau AR, Robinson S, Yu C, Poulton S, Kirkby JC, Stocks J et al. ( 2013 ) . Prenatal vitamin d supplementation and child respiratory health: a randomised controlled trial . PLoS One vol. 8 , ( 6 )
Martineau AR, Investigators AT ( 2012 ) . Reply to Grey and Bolland: Findings of prespecified per-protocol analysis are valid . PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA vol. 109 , ( 51 ) E3529 - E3529 .
Martineau AR, Coussens AK, Nikolayevskyy V, Elkington PT, Bothamley GH, Packe GE, Darmalingam M, Drobniewski FA et al. ( 2012 ) . ETHNIC VARIATION IN INFLAMMATORY PROFILE IN TUBERCULOSIS . THORAX . vol. 67 , A4 - A4 .
Klassen K, Martineau AR, Wilkinson RJ, Hickson M ( 2012 ) . TENOFOVIR AND CALCIUM METABOLISM IN HIV-INFECTED ADULTS . OSTEOPOROSIS INTERNATIONAL . vol. 23 , S751 - S752 .
Jolliffe DA, Martineau AR, Griffiths CJ ( 2012 ) . VITAMIN D IN THE PREVENTION OF ACUTE RESPIRATORY INFECTION: A SYSTEMATIC REVIEW OF CLINICAL STUDIES . THORAX . vol. 67 , A71 - A72 .
Dancer R, Parekh D, Martineau A, Perkins G, Thickett ( 2012 ) . S75 High Dose Vitamin D Supplementation Improves Extravascular Lung Water Index and In-Vivo Treg and LL37 Responses Post-Oesophagectomy . Thorax vol. 67 , ( Suppl 2 ) a38 - a38 .
Martineau A ( 2012 ) . High dose vitamin D speeds recovery from tuberculosis . British Journal of Hospital Medicine vol. 73 , ( 10 ) 548 - 548 .
Coussens AK, Wilkinson RJ, Hanifa Y, Nikolayevskyy V, Elkington PT, Islam K, Timms PM, Venton TR et al. ( 2012 ) . Vitamin D accelerates resolution of inflammatory responses during tuberculosis treatment . Proc Natl Acad Sci U S A vol. 109 , ( 38 ) 15449 - 15454 .
James WY, Jolliffe D, Islam K, Maclaughlin B, Griffiths C, Gibbon M, Fenn J, Morrisey D et al. ( 2012 ) . Measurement of quadriceps strength in patients with COPD using a rig-supported handheld dynamometer . EUROPEAN RESPIRATORY JOURNAL . vol. 40 ,
James WY, Jolliffe D, Islam K, Griffiths C, Martineau A ( 2012 ) . Over-diagnosis of COPD in UK primary care . EUROPEAN RESPIRATORY JOURNAL . vol. 40 ,
Chambers ES, Nanzer AM, Richards DF, Ryanna K, Freeman AT, Timms PM, Martineau AR, Griffiths CJ et al. ( 2012 ) . Serum 25-dihydroxyvitamin D levels correlate with CD4(+)Foxp3(+) T-cell numbers in moderate/severe asthma . JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY vol. 130 , ( 2 ) 542 - 544 .
Martineau AR ( 2012 ) . Tuberculosis . Vitamin D and the Lung , Editors: Litonjua, AA , Humana PressInc
Martineau AR ( 2012 ) . Bolus-dose vitamin D and prevention of childhood pneumonia . Lancet vol. 379 , ( 9824 ) 1373 - 1375 .
Finer S, Khan KS, Hitman GA, Griffiths C, Martineau A, Meads C ( 2012 ) . Inadequate vitamin D status in pregnancy: evidence for supplementation . Acta Obstet Gynecol Scand vol. 91 , ( 2 ) 159 - 163 .
Martineau AR ( 2012 ) . Old wine in new bottles: vitamin D in the treatment and prevention of tuberculosis . Proc Nutr Soc vol. 71 , ( 1 ) 84 - 89 .
Shaheen SO, Martineau AR ( 2012 ) . Vitamin D and Chronic Obstructive Pulmonary Disease: Justified Optimism or False Hope? . AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE vol. 185 , ( 3 ) 239 - 241 .
Conesa-Botella A, Meintjes G, Coussens AK, van der Plas H, Goliath R, Schutz C, Moreno-Reyes R, Mehta M et al. ( 2012 ) . Corticosteroid Therapy, Vitamin D Status, and Inflammatory Cytokine Profile in the HIV-Tuberculosis Immune Reconstitution Inflammatory Syndrome . Clin Infect Dis vol. 55 , ( 7 ) 1004 - 1011 .
Lowe DM, Redford PS, Wilkinson RJ, O'Garra A, Martineau AR ( 2012 ) . Neutrophils in tuberculosis: friend or foe? . Trends Immunol vol. 33 , ( 1 ) 14 - 25 .
Mansbach JM, Piedra PA, Borregaard N, Martineau AR, Neuman MI, Espinola JA, Camargo CA ( 2012 ) . Serum cathelicidin level is associated with viral etiology and severity of bronchiolitis . J Allergy Clin Immunol vol. 130 , ( 4 )
Lavender TW, Martineau AR, Quinton R, Schwab U ( 2012 ) . Severe hypercalcaemia following vitamin D replacement for tuberculosis-associated hypovitaminosis D . INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE vol. 16 , ( 1 ) 140 - 140 .
Klassen K, Martineau AR, Wilkinson RJ, Cooke G, Courtney AP, Hickson M ( 2012 ) . The effect of tenofovir on vitamin D metabolism in HIV-infected adults is dependent on sex and ethnicity . PLoS One vol. 7 , ( 9 )
Nanzer AM, Chambers ES, Ryanna K, Richards DF, Freeman A, Martineau AR, Xystrakis E, Corrigan CJ et al. ( 2011 ) . Differential production of IL-17 expression in peripheral blood cultures of steroid refractory versus steroid sensitive asthmatics . IMMUNOLOGY . vol. 135 , 188 - 188 .
Nanzer AM, Chambers ES, Richards DF, Timms PM, Martineau AR, Corrigan CJ, Griffiths CJ, Hawrylowicz CM ( 2011 ) . Steroid refractory asthma patients express lower levels of the immunomodulatory transcription factor FoxP3 and have lower levels of serum vitamin D . CLINICAL AND EXPERIMENTAL ALLERGY . vol. 41 , 1840 - 1840 .
Mitchell K, Griffiths CJ, Martineau AR ( 2011 ) . Vitamin D and tuberculosis . Current Respiratory Medicine Reviews vol. 7 , ( 6 ) 435 - 439 .
Martineau AR, Nhamoyebonde S, Oni T, Rangaka MX, Marais S, Bangani N, Tsekela R, Bashe L et al. ( 2011 ) . Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa . Proc Natl Acad Sci U S A vol. 108 , ( 47 ) 19013 - 19017 .
Newton S, Martineau A, Kampmann B ( 2011 ) . A functional whole blood assay to measure viability of mycobacteria, using reporter-gene tagged BCG or M.Tb (BCGlux/M.Tb lux) . J Vis Exp ( 55 )
Martineau A, Griffiths C ( 2011 ) . Nutritional status and vitamin D-3 during antimicrobial treatment Reply . LANCET vol. 377 , ( 9775 ) 1408 - 1408 .
Fenn J, Martineau A, Yee JW, Islam K, Griffiths C, Maffulli N, Morrissey D ( 2011 ) . An evaluation of the relationship between vitamin d status and quadriceps strength in patients with copd: a cross sectional study . British Journal of Sports Medicine vol. 45 , ( 2 )
Martineau AR, Timms PM, Bothamley GH, Hanifa Y, Islam K, Claxton AP, Packe GE, Moore-Gillon JC et al. ( 2011 ) . High-dose vitamin D(3) during intensive-phase antimicrobial treatment of pulmonary tuberculosis: a double-blind randomised controlled trial . Lancet vol. 377 , ( 9761 ) 242 - 250 .
Lanham-New SA, Buttriss JL, Miles LM, Ashwell M, Berry JL, Boucher BJ, Cashman KD, Cooper C et al. ( 2011 ) . Proceedings of the rank forum on vitamin D . British Journal of Nutrition . vol. 105 , 144 - 156 .
MARTINEAU AR, NHAMOYEBONDE S, ONI T, RANGAKA MX, MARAIS S, BANGANI N, TSEKELA R, BASHE L et al. ( 2011 ) . Reciprocal seasonal variation in vitamin D status and tuberculosis notifications in Cape Town, South Africa . Proceedings of the National Academy of Sciences of USA vol. 108 , ( 47 ) 19013 - 19017 .
Martineau AR ( 2011 ) . Vitamin D and Respiratory Health . Current Respiratory Medicine Reviews vol. 7 , ( 6 ) 394 - 395 .
Coussens AK, Wilkinson RJ, Hanifa Y, Griffiths CJ, Martineau AR ( 2010 ) . Increased peripheral blood lymphocyte count and decreased serum concentrations of T cell chemoattractants in tuberculosis patients receiving high-dose vitamin D-3 supplementation . IMMUNOLOGY . vol. 131 , 74 - 75 .
Chun RF, Lauridsen AL, Suon L, Zella LA, Pike JW, Modlin RL, Martineau AR, Wilkinson RJ et al. ( 2010 ) . Vitamin D-binding protein directs monocyte responses to 25-hydroxy- and 1,25-dihydroxyvitamin D . J Clin Endocrinol Metab vol. 95 , ( 7 ) 3368 - 3376 .
Martineau AR, Leandro ACCS, Anderson ST, Newton SM, Wilkinson KA, Nicol MP, Pienaar SM, Skolimowska KH et al. ( 2010 ) . Association between Gc genotype and susceptibility to TB is dependent on vitamin D status . Eur Respir J vol. 35 , ( 5 ) 1106 - 1112 .
Coussens AK, Timms PM, Boucher BJ, Venton TR, Ashcroft AT, Skolimowska KH, Newton SM, Wilkinson KA et al. ( 2009 ) . 1 alpha,25-dihydroxyvitamin D-3 inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection . IMMUNOLOGY vol. 127 , ( 4 ) 539 - 548 .
Coussens A, Timms PM, Boucher BJ, Venton TR, Ashcroft AT, Skolimowska KH, Newton SM, Wilkinson KA et al. ( 2009 ) . 1α,25-dihydroxyvitamin D<inf>3</inf> inhibits matrix metalloproteinases induced by Mycobacterium tuberculosis infection . Immunology vol. 127 , ( 4 ) 539 - 548 .
Martineau AR, Griffiths CJ, Packe GE ( 2009 ) . Improved Vitamin D Status Despite Allocation to Placebo in a Tuberculosis Treatment Trial: Contamination Bias? . AM J RESP CRIT CARE vol. 180 , ( 2 ) 189 - 189 .
Wilkinson KA, Newton SM, Stewart GR, Martineau AR, Patel J, Sullivan SM, Herrmann JL, Neyrolles O et al. ( 2009 ) . Genetic determination of the effect of post-translational modification on the innate immune response to the 19 kDa lipoprotein of Mycobacterium tuberculosis . BMC MICROBIOL vol. 9 , Article 93 ,
Martineau AR, Nanzer AM, Satkunam KR, Packe GE, Rainbow SJ, Maunsell ZJ, Timms PM, Venton TR et al. ( 2009 ) . Influence of a single oral dose of vitamin D(2) on serum 25-hydroxyvitamin D concentrations in tuberculosis patients . Int J Tuberc Lung Dis vol. 13 , ( 1 ) 119 - 125 .
Nanzer AM, Satkunam KR, Packe GE, Rainbow SJ, Maunsell ZJ, Timms PM, Venton TR, Eldridge SM et al. ( 2008 ) . INFLUENCE OF A SINGLE ORAL DOSE OF VITAMIN D2 ON SERUM 25-HYDROXYVITAMIN D CONCENTRATIONS IN TUBERCULOSIS PATIENTS . THORAX . vol. 63 , A146 - A146 .
Bandara A, Bremner S, Barker RD, Packe G, Griffiths C, Martineau A ( 2008 ) . NEUTROPHILIA IN TUBERCULOSIS . THORAX . vol. 63 , A114 - A114 .
Martineau A, Newton S, Wilkinson K, Kampmann B, Hall B, Packe G, Davidson R, Griffiths C et al. ( 2008 ) . Neutrophil-mediated innate immune resistance to mycobacteria . J INFECTION vol. 56 , ( 4 ) 301 - 302 .
Martineau AR, Wilkinson RJ, Griffiths CJ ( 2008 ) . Vitamin D and tuberculosis incidence in Spain . AM J RESP CRIT CARE vol. 177 , ( 7 ) 799 - 799 .
Newton SM, Mackie SL, Martineau AR, Wilkinson KA, Kampmann B, Fisher C, Dutta S, Levin M et al. ( 2008 ) . Reduction of chemokine secretion in response to mycobacteria in infliximab-treated patients . CLIN VACCINE IMMUNOL vol. 15 , ( 3 ) 506 - 512 .
Martineau AR, Griffiths CJ, Wilkinson RJ ( 2008 ) . Vitamin D in the treatment and prevention of tuberculosis . Expert Review of Endocrinology and Metabolism vol. 3 , ( 2 ) 105 - 107 .
Martineau AR, Wilkinson KA, Newton SM, Floto RA, Norman AW, Skolimowska K, Davidson RN, Sørensen OE et al. ( 2007 ) . IFN-γ- and TNF-independent vitamin D-inducible human suppression of mycobacteria: The role of cathelicidin LL-37 (Journal of Immunology (2007) 178 (7190-7198)) . Journal of Immunology vol. 179 , ( 12 ) 8569 - 8570 .
Martineau AR, Wilkinson RJ, Wilkinson KA, Newton SM, Kampmann B, Hall BM, Packe GE, Davidson RN et al. ( 2007 ) . A single dose of vitamin D enhances immunity to mycobacteria . Am J Respir Crit Care Med vol. 176 , ( 2 ) 208 - 213 .
Martineau AR, Newton SM, Wilkinson KA, Kampmann B, Hall BM, Nawroly N, Packe GE, Davidson RN et al. ( 2007 ) . Neutrophil-mediated innate immune resistance to mycobacteria . J CLIN INVEST vol. 117 , ( 7 ) 1988 - 1994 .
Martineau AR, Wilkinson KA, Newton SM, Floto RA, Norman AW, Skolimowska K, Davidson RN, Sorensen OE et al. ( 2007 ) . IFN-gamma- and TNF-independent vitamin D-inducible human suppression of mycobacteria: The role of cathelicidin LL-37 . J IMMUNOL vol. 178 , ( 11 ) 7190 - 7198 .
Martineau AR, Wilkinson KA, Newton SM, Floto RA, Norman AW, Skolimowska K, Davidson RN, Sørensen OE et al. ( 2007 ) . IFN-γ- and TNF-independent vitamin D-inducible human suppression of mycobacteria: The role of cathelicidin LL-37 . Journal of Immunology vol. 178 , ( 11 ) 7190 - 7198 .
Griffiths C, Sturdy P, Brewin P, Bothamley G, Eldridge S, Martineau A, MacDonald M, Ramsay J et al. ( 2007 ) . Educational outreach to promote screening for tuberculosis in primary care: a cluster randomised controlled trial . Lancet vol. 369 , ( 9572 ) 1528 - 1534 .
Newton SM, Smith RJ, Wilkinson KA, Nicol MP, Garton NJ, Fandrich S, Staples KJ, Ziegler-Heitbrock L et al. ( 2007 ) . Gene Deletion Contributes to the Virulence of an Outbreak Strain of Mycobacterium Tuberculosis via Immune Subversion . Journal of Infection vol. 54 , ( 3 ) e188 - e189 .
Martineau AR, Newton SM, Hall BM, Wilkinson KA, Kampmann B, Davidson RN, Packe GE, Maunsell Z et al. ( 2007 ) . Vitamin D Supplementation Enhances Antimycobacterial Immunity in London Tuberculosis Contacts . Journal of Infection vol. 54 , ( 3 )
Martineau AR, Honecker FU, Wilkinson RJ, Griffiths CJ ( 2007 ) . Vitamin D in the treatment of pulmonary tuberculosis . J Steroid Biochem Mol Biol . vol. 103 , 793 - 798 .
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